TreeWAS – Variant ID: rs12536985

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter IX Diseases of the circulatory system	1.000	0.000
# Top node	1.000	0.000
Chapter XXI Factors influencing health status and contact with health services	1.000	0.000
I30-I52 Other forms of heart disease	1.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	1.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000
Chapter XIV Diseases of the genitourinary system	1.000	0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	1.000	0.000
I20-I25 Ischaemic heart diseases	0.999	0.001
Chapter V Mental and behavioural disorders	0.999	0.001
I50 Heart failure	0.999	0.001
M20-M25 Other joint disorders	0.998	0.002
N17-N19 Renal failure	0.996	0.004
I50.1 Left ventricular failure	0.996	0.004
M25 Other joint disorders, not elsewhere classified	0.995	0.005
I25 Chronic ischaemic heart disease	0.991	0.009
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.988	0.012
Z92 Personal history of medical treatment	0.987	0.013
M25.5 Pain in joint	0.986	0.014
Z70-Z76 Persons encountering health services in other circumstances	0.986	0.014
Chapter VII Diseases of the eye and adnexa	0.986	0.014
Z92.2 Personal history of long-term (current) use of other medicaments	0.984	0.016
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.983	0.017
M15-M19 Arthrosis	0.982	0.018
N80-N98 Noninflammatory disorders of female genital tract	0.979	0.021
Chapter XII Diseases of the skin and subcutaneous tissue	0.975	0.025
Chapter VI Diseases of the nervous system	0.972	0.028
M19 Other arthrosis	0.967	0.033
I42 Cardiomyopathy	0.965	0.035
Chapter XX External causes of morbidity and mortality	0.963	0.037
Z72 Problems related to lifestyle	0.958	0.042
E10-E14 Diabetes mellitus	0.958	0.042
Z95 Presence of cardiac and vascular implants and grafts	0.956	0.044
I25.1 Atherosclerotic heart disease	0.956	0.044
Z86 Personal history of certain other diseases	0.955	0.045
E70-E90 Metabolic disorders	0.954	0.046
E65-E68 Obesity and other hyperalimentation	0.953	0.047
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.952	0.048
F40-F48 Neurotic, stress-related and somatoform disorders	0.951	0.049
N19 Unspecified renal failure	0.950	0.050
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.948	0.052
R20 Disturbances of skin sensation	0.946	0.054
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.944	0.056
Chapter I Certain infectious and parasitic diseases	0.943	0.057
N18 Chronic renal failure	0.941	0.059
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.935	0.065
I51 Complications and ill-defined descriptions of heart disease	0.928	0.072
F30-F39 Mood [affective] disorders	0.924	0.076
I50.0 Congestive heart failure	0.923	0.077
M25.55 Pain in joint (Pelvic region and thigh)	0.921	0.079
N17 Acute renal failure	0.919	0.081
I20 Angina pectoris	0.918	0.082
M19.9 Arthrosis, unspecified	0.917	0.083
Z98 Other postsurgical states	0.915	0.085
N81 Female genital prolapse	0.912	0.088
N10-N16 Renal tubulo-interstitial diseases	0.908	0.092
Z95.1 Presence of aortocoronary bypass graft	0.908	0.092
M19.0 Primary arthrosis of other joints	0.908	0.092
E00-E07 Disorders of thyroid gland	0.907	0.093
I25.8 Other forms of chronic ischaemic heart disease	0.904	0.096
Z96 Presence of other functional implants	0.902	0.098
F00-F09 Organic, including symptomatic, mental disorders	0.901	0.099
E66 Obesity	0.901	0.099
E87 Other disorders of fluid, electrolyte and acid-base balance	0.901	0.099
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.900	0.100
N70-N77 Inflammatory diseases of female pelvic organs	0.898	0.102
I70-I79 Diseases of arteries, arterioles and capillaries	0.897	0.103
I22 Subsequent myocardial infarction	0.896	0.104
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.895	0.105
R50-R69 General symptoms and signs	0.892	0.108
E10 Insulin-dependent diabetes mellitus	0.892	0.108
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.892	0.108
R20.2 Paraesthesia of skin	0.891	0.109
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.889	0.111
M22 Disorders of patella	0.889	0.111
N86 Erosion and ectropion of cervix uteri	0.889	0.111
I25.2 Old myocardial infarction	0.888	0.112
Z98.0 Intestinal bypass and anastomosis status	0.888	0.112
M25.54 Pain in joint (Hand)	0.888	0.112
Z86.7 Personal history of diseases of the circulatory system	0.887	0.113
L20-L30 Dermatitis and eczema	0.886	0.114
M20 Acquired deformities of fingers and toes	0.886	0.114
I31 Other diseases of pericardium	0.886	0.114
M25.7 Osteophyte	0.885	0.115
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.885	0.115
Z72.1 Alcohol use	0.883	0.117
M19.94 Arthrosis, unspecified (Hand)	0.877	0.123
N81.6 Rectocele	0.877	0.123
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.877	0.123
E50-E64 Other nutritional deficiencies	0.876	0.124
I42.9 Cardiomyopathy, unspecified	0.876	0.124
M16 Coxarthrosis [arthrosis of hip]	0.875	0.125
Z72.0 Tobacco use	0.873	0.127
L00-L08 Infections of the skin and subcutaneous tissue	0.872	0.128
R22.3 Localised swelling, mass and lump, upper limb	0.871	0.129
I20.0 Unstable angina	0.871	0.129
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.869	0.131
N88 Other noninflammatory disorders of cervix uteri	0.868	0.132
E40-E46 Malnutrition	0.867	0.133
Z95.8 Presence of other cardiac and vascular implants and grafts	0.867	0.133
F40 Phobic anxiety disorders	0.863	0.137
N17.9 Acute renal failure, unspecified	0.863	0.137
R63 Symptoms and signs concerning food and fluid intake	0.861	0.139
I46 Cardiac arrest	0.860	0.140
F41 Other anxiety disorders	0.860	0.140
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.859	0.141
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.859	0.141
M50-M54 Other dorsopathies	0.857	0.142
I95-I99 Other and unspecified disorders of the circulatory system	0.857	0.143
E87.2 Acidosis	0.856	0.144
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.856	0.144
Chapter VIII Diseases of the ear and mastoid process	0.855	0.145
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.854	0.146
Z96.6 Presence of orthopaedic joint implants	0.853	0.147
Z86.4 Personal history of psychoactive substance abuse	0.851	0.149
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.850	0.150
F31 Bipolar affective disorder	0.848	0.152
G40-G47 Episodic and paroxysmal disorders	0.845	0.155
N94 Pain and other conditions associated with female genital organs and menstrual cycle	0.844	0.156
L60-L75 Disorders of skin appendages	0.843	0.157
S00-S09 Injuries to the head	0.841	0.159
E66.9 Obesity, unspecified	0.840	0.160
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.840	0.160
H53-H54 Visual disturbances and blindness	0.838	0.162
G70-G73 Diseases of myoneural junction and muscle	0.837	0.163
I24 Other acute ischaemic heart diseases	0.836	0.164
F99-F99 Unspecified mental disorder	0.835	0.165
G50-G59 Nerve, nerve root and plexus disorders	0.833	0.167
M25.56 Pain in joint (Lower leg)	0.833	0.167
A30-A49 Other bacterial diseases	0.832	0.168
R63.4 Abnormal weight loss	0.832	0.168
H55-H59 Other disorders of eye and adnexa	0.831	0.169
S70-S79 Injuries to the hip and thigh	0.831	0.169
N85 Other noninflammatory disorders of uterus, except cervix	0.831	0.169
Z89 Acquired absence of limb	0.829	0.171
M25.57 Pain in joint (Ankle and foot)	0.826	0.174
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.825	0.175
R60 Oedema, not elsewhere classified	0.825	0.175
E05 Thyrotoxicosis [hyperthyroidism]	0.825	0.175
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.825	0.175
S80-S89 Injuries to the knee and lower leg	0.824	0.176
N92 Excessive, frequent and irregular menstruation	0.822	0.178
I49 Other cardiac arrhythmias	0.820	0.179
N60-N64 Disorders of breast	0.820	0.180
R26 Abnormalities of gait and mobility	0.820	0.180
L50-L54 Urticaria and erythema	0.820	0.180
E11 Non-insulin-dependent diabetes mellitus	0.819	0.181
L30 Other dermatitis	0.817	0.183
I51.7 Cardiomegaly	0.817	0.183
I05-I09 Chronic rheumatic heart diseases	0.815	0.185
M05-M14 Inflammatory polyarthropathies	0.815	0.185
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.812	0.188
M19.90 Arthrosis, unspecified (Multiple sites)	0.812	0.188
I42.8 Other cardiomyopathies	0.812	0.188
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.811	0.189
M19.99 Arthrosis, unspecified (Site unspecified)	0.808	0.192
I10-I15 Hypertensive diseases	0.808	0.192
M22.4 Chondromalacia patellae	0.807	0.193
M65-M68 Disorders of synovium and tendon	0.807	0.193
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.807	0.193
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.806	0.194
R25 Abnormal involuntary movements	0.805	0.195
G90-G99 Other disorders of the nervous system	0.804	0.196
R20.8 Other and unspecified disturbances of skin sensation	0.802	0.198
Z00-Z13 Persons encountering health services for examination and investigation	0.802	0.198
L08 Other local infections of skin and subcutaneous tissue	0.801	0.199
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.801	0.199
F10 Mental and behavioural disorders due to use of alcohol	0.800	0.200
F40.2 Specific (isolated) phobias	0.800	0.200
R58 Haemorrhage, not elsewhere classified	0.797	0.203
M25.59 Pain in joint (Site unspecified)	0.796	0.204
I73 Other peripheral vascular diseases	0.794	0.206
H10-H13 Disorders of conjunctiva	0.794	0.206
N85.2 Hypertrophy of uterus	0.794	0.206
H43-H45 Disorders of vitreous body and globe	0.793	0.206
Z03 Medical observation and evaluation for suspected diseases and conditions	0.792	0.208
F33 Recurrent depressive disorder	0.790	0.209
N88.8 Other specified noninflammatory disorders of cervix uteri	0.790	0.210
N89 Other noninflammatory disorders of vagina	0.790	0.210
Z90 Acquired absence of organs, not elsewhere classified	0.789	0.211
N94.8 Other specified conditions associated with female genital organs and menstrual cycle	0.789	0.211
F20 Schizophrenia	0.788	0.212
W00-W19 Falls	0.787	0.213
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.785	0.215
B95-B98 Bacterial, viral and other infectious agents	0.785	0.215
N18.3 Chronic kidney disease, stage 3	0.784	0.216
R60.0 Localised oedema	0.784	0.216
I22.9 Subsequent myocardial infarction of unspecified site	0.784	0.216
I21 Acute myocardial infarction	0.784	0.216
R22.4 Localised swelling, mass and lump, lower limb	0.784	0.216
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.783	0.217
R41 Other symptoms and signs involving cognitive functions and awareness	0.783	0.217
E03 Other hypothyroidism	0.782	0.218
E65 Localised adiposity	0.782	0.218
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.781	0.219
M25.8 Other specified joint disorders	0.781	0.219
I42.0 Dilated cardiomyopathy	0.780	0.220
E53 Deficiency of other B group vitamins	0.780	0.220
Z73 Problems related to life-management difficulty	0.780	0.220
E78.0 Pure hypercholesterolaemia	0.779	0.221
G40 Epilepsy	0.778	0.222
N18.9 Chronic renal failure, unspecified	0.777	0.222
Chapter XXII Codes for special purposes	0.776	0.224
F05 Delirium, not induced by alcohol and other psychoactive substances	0.774	0.226
E05.9 Thyrotoxicosis, unspecified	0.772	0.228
I51.8 Other ill-defined heart diseases	0.772	0.228
E46 Unspecified protein-energy malnutrition	0.772	0.228
N18.2 Chronic kidney disease, stage 2	0.771	0.229
R54 Senility	0.771	0.229
I25.5 Ischaemic cardiomyopathy	0.771	0.229
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.770	0.230
H04 Disorders of lachrymal system	0.770	0.230
Z86.6 Personal history of diseases of the nervous system and sense organs	0.769	0.231
L30.9 Dermatitis, unspecified	0.768	0.232
R22.1 Localised swelling, mass and lump, neck	0.768	0.232
R44 Other symptoms and signs involving general sensations and perceptions	0.768	0.232
T15-T19 Effects of foreign body entering through natural orifice	0.767	0.233
M20.5 Other deformities of toe(s) (acquired)	0.764	0.236
B25-B34 Other viral diseases	0.764	0.236
E10.9 Without complications	0.764	0.236
Z71.9 Counselling, unspecified	0.764	0.236
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.763	0.237
Z97 Presence of other devices	0.762	0.238
N76 Other inflammation of vagina and vulva	0.761	0.239
D60-D64 Aplastic and other anaemias	0.761	0.239
M40-M43 Deforming dorsopathies	0.761	0.239
Z03.8 Observation for other suspected diseases and conditions	0.759	0.241
Z86.1 Personal history of infectious and parasitic diseases	0.759	0.241
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.758	0.242
E10.5 With peripheral circulatory complications	0.758	0.242
Z71.1 Person with feared complaint in whom no diagnosis is made	0.756	0.244
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.755	0.245
M19.04 Primary arthrosis of other joints (Hand)	0.754	0.246
H90-H95 Other disorders of ear	0.753	0.247
R80 Isolated proteinuria	0.753	0.247
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.750	0.249
I31.3 Pericardial effusion (noninflammatory)	0.749	0.251
M80-M85 Disorders of bone density and structure	0.747	0.253
N70 Salpingitis and oophoritis	0.746	0.254
Z99.1 Dependence on respirator	0.746	0.254
N18.4 Chronic kidney disease, stage 4	0.746	0.254
N87 Dysplasia of cervix uteri	0.746	0.254
M25.76 Osteophyte (Lower leg)	0.745	0.255
I46.0 Cardiac arrest with successful resuscitation	0.745	0.255
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.744	0.256
N72 Inflammatory disease of cervix uteri	0.744	0.256
E66.8 Other obesity	0.743	0.257
I30 Acute pericarditis	0.743	0.257
N18.5 Chronic kidney disease, stage 5	0.743	0.257
I42.2 Other hypertrophic cardiomyopathy	0.743	0.257
R18 Ascites	0.742	0.258
I73.9 Peripheral vascular disease, unspecified	0.741	0.259
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.740	0.260
M19.02 Primary arthrosis of other joints (Upper arm)	0.740	0.260
Y84.8 Other medical procedures	0.740	0.260
R22.2 Localised swelling, mass and lump, trunk	0.740	0.260
I20.8 Other forms of angina pectoris	0.739	0.261
M19.01 Primary arthrosis of other joints (Shoulder region)	0.738	0.262
M54 Dorsalgia	0.737	0.263
F60-F69 Disorders of adult personality and behaviour	0.737	0.263
M21 Other acquired deformities of limbs	0.737	0.263
Z93 Artificial opening status	0.737	0.263
Z95.0 Presence of cardiac pacemaker	0.737	0.263
M20.2 Hallux rigidus	0.736	0.264
I31.9 Disease of pericardium, unspecified	0.736	0.264
Chapter II Neoplasms	0.736	0.264
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.736	0.264
S72 Fracture of femur	0.736	0.264
M45-M49 Spondylopathies	0.735	0.264
R30-R39 Symptoms and signs involving the urinary system	0.735	0.265
L72 Follicular cysts of skin and subcutaneous tissue	0.734	0.266
E06 Thyroiditis	0.734	0.266
N81.1 Cystocele	0.733	0.267
H52 Disorders of refraction and accommodation	0.733	0.267
M25.51 Pain in joint (Shoulder region)	0.733	0.267
N00-N08 Glomerular diseases	0.732	0.268
M16.1 Other primary coxarthrosis	0.732	0.268
Y60-Y69 Misadventures to patients during surgical and medical care	0.731	0.269
H46-H48 Disorders of optic nerve and visual pathways	0.731	0.269
M25.75 Osteophyte (Pelvic region and thigh)	0.731	0.269
I22.1 Subsequent myocardial infarction of inferior wall	0.730	0.270
N81.3 Complete uterovaginal prolapse	0.730	0.270
E87.5 Hyperkalaemia	0.729	0.271
R82 Other abnormal findings in urine	0.728	0.272
S06 Intracranial injury	0.728	0.272
N11 Chronic tubulo-interstitial nephritis	0.728	0.272
S00 Superficial injury of head	0.727	0.273
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.727	0.273
Z99.3 Dependence on wheelchair	0.727	0.273
Z72.2 Drug use	0.727	0.273
Z90.1 Acquired absence of breast(s)	0.727	0.273
M31 Other necrotising vasculopathies	0.726	0.274
B35-B49 Mycoses	0.726	0.274
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.725	0.275
M25.53 Pain in joint (Forearm)	0.724	0.276
I51.9 Heart disease, unspecified	0.724	0.276
I42.1 Obstructive hypertrophic cardiomyopathy	0.723	0.277
M24 Other specific joint derangements	0.722	0.278
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.721	0.279
H57 Other disorders of eye and adnexa	0.721	0.279
F10.2 Dependence syndrome	0.720	0.280
F43 Reaction to severe stress, and adjustment disorders	0.720	0.280
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.719	0.281
Y52 Agents primarily affecting the cardiovascular system	0.719	0.281
N92.4 Excessive bleeding in the premenopausal period	0.719	0.281
E78.5 Hyperlipidaemia, unspecified	0.718	0.282
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.717	0.282
F99 Mental disorder, not otherwise specified	0.717	0.283
F80-F89 Disorders of psychological development	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
I52 Other heart disorders in diseases classified elsewhere	0.717	0.283
I48 Atrial fibrillation and flutter	0.717	0.283
I43 Cardiomyopathy in diseases classified elsewhere	0.717	0.283
I41 Myocarditis in diseases classified elsewhere	0.717	0.283
I40 Acute myocarditis	0.717	0.283
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.717	0.283
I37 Pulmonary valve disorders	0.717	0.283
I36 Nonrheumatic tricuspid valve disorders	0.717	0.283
I33 Acute and subacute endocarditis	0.717	0.283
I32 Pericarditis in diseases classified elsewhere	0.717	0.283
M91-M94 Chondropathies	0.717	0.283
M60-M63 Disorders of muscles	0.717	0.283
M00-M03 Infectious arthropathies	0.717	0.283
R95-R99 Ill-defined and unknown causes of mortality	0.717	0.283
Z84 Family history of other conditions	0.717	0.283
Z81 Family history of mental and behavioural disorders	0.717	0.283
I72 Other aneurysm	0.717	0.283
I23 Certain current complications following acute myocardial infarction	0.717	0.283
H50 Other strabismus	0.717	0.283
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.716	0.283
F70-F79 Mental retardation	0.716	0.283
E14 Unspecified diabetes mellitus	0.717	0.283
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.716	0.284
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.716	0.284
M34 Systemic sclerosis	0.716	0.284
M33 Dermatopolymyositis	0.716	0.284
M32 Systemic lupus erythematosus	0.716	0.284
M30 Polyarteritis nodosa and related conditions	0.716	0.284
Z94 Transplanted organ and tissue status	0.716	0.284
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.715	0.285
F10.1 Harmful use	0.714	0.286
L03 Cellulitis	0.713	0.287
M25.9 Joint disorder, unspecified	0.713	0.287
M25.6 Stiffness of joint, not elsewhere classified	0.713	0.287
M25.3 Other instability of joint	0.713	0.287
M25.2 Flail joint	0.713	0.287
M25.1 Fistula of joint	0.713	0.287
M25.0 Haemarthrosis	0.713	0.287
R32 Unspecified urinary incontinence	0.713	0.287
I45 Other conduction disorders	0.713	0.287
N13 Obstructive and reflux uropathy	0.712	0.288
A41 Other septicaemia	0.712	0.288
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.711	0.289
M86-M90 Other osteopathies	0.711	0.289
E53.8 Deficiency of other specified B group vitamins	0.711	0.289
I25.6 Silent myocardial ischaemia	0.711	0.289
I25.4 Coronary artery aneurysm	0.711	0.289
I25.3 Aneurysm of heart	0.711	0.289
I25.0 Atherosclerotic cardiovascular disease, so described	0.711	0.289
E10.4 With neurological complications	0.710	0.290
S10-S19 Injuries to the neck	0.709	0.291
M35 Other systemic involvement of connective tissue	0.709	0.291
N85.4 Malposition of uterus	0.709	0.291
Z90.7 Acquired absence of genital organ(s)	0.708	0.292
Z92.9 Personal history of medical treatment, unspecified	0.708	0.292
Z92.8 Personal history of other medical treatment	0.708	0.292
Z92.5 Personal history of rehabilitation measures	0.708	0.292
Z92.0 Personal history of contraception	0.708	0.292
M25.4 Effusion of joint	0.708	0.292
M25.58 Pain in joint (Other)	0.707	0.293
M25.52 Pain in joint (Upper arm)	0.707	0.293
Z76 Persons encountering health services in other circumstances	0.707	0.293
Z70 Counselling related to sexual attitude, behaviour and orientation	0.707	0.293
R25.1 Tremor, unspecified	0.707	0.293
S81 Open wound of lower leg	0.707	0.293
R57 Shock, not elsewhere classified	0.706	0.294
Z03.4 Observation for suspected myocardial infarction	0.705	0.295
M15 Polyarthrosis	0.704	0.296
I49.9 Cardiac arrhythmia, unspecified	0.703	0.297
Y95 Nosocomial condition	0.702	0.298
L72.1 Trichilemmal cyst	0.702	0.298
N98 Complications associated with artificial fertilisation	0.702	0.298
N91 Absent, scanty and rare menstruation	0.702	0.298
N82 Fistulae involving female genital tract	0.702	0.298
N96 Habitual aborter	0.702	0.298
G70 Myasthenia gravis and other myoneural disorders	0.702	0.298
I34 Nonrheumatic mitral valve disorders	0.702	0.298
H54 Blindness and low vision	0.702	0.298
G40.9 Epilepsy, unspecified	0.701	0.299
G55.2 Nerve root and plexus compressions in spondylosis	0.701	0.299
E16 Other disorders of pancreatic internal secretion	0.700	0.300
Z96.1 Presence of intraocular lens	0.700	0.300
I12 Hypertensive renal disease	0.700	0.300
R45 Symptoms and signs involving emotional state	0.700	0.300
L10-L14 Bullous disorders	0.699	0.301
Q38-Q45 Other congenital malformations of the digestive system	0.699	0.301
L40-L45 Papulosquamous disorders	0.698	0.302
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.698	0.302
R27 Other lack of coordination	0.697	0.302
Z99.8 Dependence on other enabling machines and devices	0.697	0.303
G00-G09 Inflammatory diseases of the central nervous system	0.697	0.303
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.697	0.303
G30-G32 Other degenerative diseases of the nervous system	0.696	0.303
G63 Polyneuropathy in diseases classified elsewhere	0.696	0.304
Z29 Need for other prophylactic measures	0.696	0.304
N80 Endometriosis	0.695	0.305
F33.9 Recurrent depressive disorder, unspecified	0.695	0.305
E87.6 Hypokalaemia	0.695	0.305
M19.92 Arthrosis, unspecified (Upper arm)	0.694	0.306
Z11 Special screening examination for infectious and parasitic diseases	0.694	0.306
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.694	0.306
G93 Other disorders of brain	0.694	0.306
M19.8 Other specified arthrosis	0.693	0.307
M19.2 Other secondary arthrosis	0.693	0.307
M19.1 Posttraumatic arthrosis of other joints	0.693	0.307
Z74 Problems related to care-provider dependency	0.693	0.307
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.693	0.307
E03.9 Hypothyroidism, unspecified	0.693	0.307
I42.7 Cardiomyopathy due to drugs and other external agents	0.692	0.308
I42.6 Alcoholic cardiomyopathy	0.692	0.308
I42.5 Other restrictive cardiomyopathy	0.692	0.308
I42.4 Endocardial fibroelastosis	0.692	0.308
I42.3 Endomyocardial (eosinophilic) disease	0.692	0.308
M20.1 Hallux valgus (acquired)	0.692	0.308
M51 Other intervertebral disk disorders	0.692	0.308
F25 Schizoaffective disorders	0.691	0.309
M19.09 Primary arthrosis of other joints (Site unspecified)	0.691	0.309
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.691	0.309
Y35-Y36 Legal intervention and operations of war	0.691	0.309
Y10-Y34 Event of undetermined intent	0.691	0.309
Y00-Y09 Assault	0.691	0.309
X85-X99 Assault	0.691	0.309
X60-X84 Intentional self-harm	0.691	0.309
X58-X59 Accidental exposure to other and unspecified factors	0.691	0.309
X50-X57 Overexertion, travel and privation	0.691	0.309
X40-X49 Accidental poisoning by and exposure to noxious substances	0.691	0.309
X30-X39 Exposure to forces of nature	0.691	0.309
X20-X29 Contact with venomous animals and plants	0.691	0.309
X10-X19 Contact with heat and hot substances	0.691	0.309
X00-X09 Exposure to smoke, fire and flames	0.691	0.309
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.691	0.309
W75-W84 Other accidental threats to breathing	0.691	0.309
W65-W74 Accidental drowning and submersion	0.691	0.309
W50-W64 Exposure to animate mechanical forces	0.691	0.309
V98-V99 Other and unspecified transport accidents	0.691	0.309
V95-V97 Air and space transport accidents	0.691	0.309
V90-V94 Water transport accidents	0.691	0.309
V80-V89 Other land transport accidents	0.691	0.309
V70-V79 Bus occupant injured in transport accident	0.691	0.309
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.691	0.309
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.691	0.309
V40-V49 Car occupant injured in transport accident	0.691	0.309
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.691	0.309
V01-V09 Pedestrian injured in transport accident	0.691	0.309
M16.3 Other dysplastic coxarthrosis	0.691	0.309
Y57 Other and unspecified drugs and medicaments	0.690	0.310
R81 Glycosuria	0.690	0.310
R15 Faecal incontinence	0.690	0.310
H60-H62 Diseases of external ear	0.689	0.311
V20-V29 Motorcycle rider injured in transport accident	0.689	0.311
W20-W49 Exposure to inanimate mechanical forces	0.687	0.312
H25-H28 Disorders of lens	0.687	0.313
E88 Other metabolic disorders	0.687	0.313
Z72.9 Problem related to lifestyle, unspecified	0.687	0.313
Z72.8 Other problems related to lifestyle	0.687	0.313
Z72.6 Gambling and betting	0.687	0.313
Z72.5 High-risk sexual behaviour	0.687	0.313
Z72.4 Inappropriate diet and eating habits	0.687	0.313
Z72.3 Lack of physical exercise	0.687	0.313
G61 Inflammatory polyneuropathy	0.687	0.313
E13 Other specified diabetes mellitus	0.687	0.313
E12 Malnutrition-related diabetes mellitus	0.687	0.313
Z95.3 Presence of xenogenic heart valve	0.686	0.314
M19.98 Arthrosis, unspecified (Other)	0.685	0.315
E85 Amyloidosis	0.684	0.316
E84 Cystic fibrosis	0.684	0.316
E79 Disorders of purine and pyrimidine metabolism	0.684	0.316
E77 Disorders of glycoprotein metabolism	0.684	0.316
E76 Disorders of glycosaminoglycan metabolism	0.684	0.316
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.684	0.316
E74 Other disorders of carbohydrate metabolism	0.684	0.316
E73 Lactose intolerance	0.684	0.316
E72 Other disorders of amino-acid metabolism	0.684	0.316
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.684	0.316
E70 Disorders of aromatic amino-acid metabolism	0.684	0.316
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.684	0.316
E83 Disorders of mineral metabolism	0.684	0.316
E67 Other hyperalimentation	0.683	0.316
E68 Sequelae of hyperalimentation	0.683	0.316
E11.2 With renal complications	0.683	0.317
M25.77 Osteophyte (Ankle and foot)	0.683	0.317
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.683	0.317
M16.0 Primary coxarthrosis, bilateral	0.683	0.317
H90 Conductive and sensorineural hearing loss	0.683	0.317
R29.4 Clicking hip	0.682	0.317
R29.3 Abnormal posture	0.682	0.317
R29.2 Abnormal reflex	0.682	0.317
R29.1 Meningismus	0.682	0.317

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations