TreeWAS – Variant ID: rs12543318

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
O03.9 Complete or unspecified, without complication	0.000	0.991	0.009
I20.0 Unstable angina	0.008	0.992	0.000
K91.4 Colostomy and enterostomy malfunction	0.008	0.992	0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.000	0.992	0.008
O03 Spontaneous abortion	0.000	0.993	0.007
O03.4 Incomplete, without complication	0.000	0.993	0.007
O03.3 Incomplete, with other and unspecified complications	0.000	0.994	0.006
O03.1 Incomplete, complicated by delayed or excessive haemorrhage	0.000	0.994	0.006
S22.40 Multiple fractures of ribs (closed)	0.000	0.994	0.006
S92 Fracture of foot, except ankle	0.006	0.994	0.000
O03.7 Complete or unspecified, complicated by embolism	0.000	0.995	0.005
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.000	0.995	0.005
O03.2 Incomplete, complicated by embolism	0.000	0.995	0.005
O03.0 Incomplete, complicated by genital tract and pelvic infection	0.000	0.995	0.005
S92.5 Fracture of other toe	0.005	0.995	0.000
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg	0.000	0.995	0.005
S92.4 Fracture of great toe	0.005	0.995	0.000
S92.0 Fracture of calcaneus	0.005	0.995	0.000
K52.8 Other specified non-infective gastro-enteritis and colitis	0.005	0.995	0.000
S92.7 Multiple fractures of foot	0.005	0.995	0.000
S92.40 Fracture of great toe (closed)	0.005	0.995	0.000
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.000	0.995	0.005
S92.00 Fracture of calcaneus (closed)	0.005	0.995	0.000
X49.9 Unspecified place	0.000	0.995	0.005
S92.51 Fracture of other toe (open)	0.005	0.995	0.000
O03.8 Complete or unspecified, with other and unspecified complications	0.000	0.995	0.005
S92.70 Multiple fractures of foot (closed)	0.005	0.995	0.000
S92.50 Fracture of other toe (closed)	0.005	0.995	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.005	0.995	0.000
S92.1 Fracture of talus	0.005	0.995	0.000
C90.0 Multiple myeloma	0.005	0.995	0.000
S90-S99 Injuries to the ankle and foot	0.005	0.995	0.000
S93.0 Dislocation of ankle joint	0.005	0.995	0.000
S93.1 Dislocation of toe(s)	0.004	0.996	0.000
S22.4 Multiple fractures of ribs	0.000	0.996	0.004
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods	0.004	0.996	0.000
S92.10 Fracture of talus (closed)	0.004	0.996	0.000
S92.9 Fracture of foot, unspecified	0.004	0.996	0.000
G44.2 Tension-type headache	0.000	0.996	0.004
S97 Crushing injury of ankle and foot	0.004	0.996	0.000
S92.41 Fracture of great toe (open)	0.004	0.996	0.000
S92.01 Fracture of calcaneus (open)	0.004	0.996	0.000
S91 Open wound of ankle and foot	0.004	0.996	0.000
N36.0 Urethral fistula	0.004	0.996	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.004	0.996	0.000
S92.2 Fracture of other tarsal bone(s)	0.004	0.996	0.000
N36.2 Urethral caruncle	0.004	0.996	0.000
S99 Other and unspecified injuries of ankle and foot	0.004	0.996	0.000
S92.71 Multiple fractures of foot (open)	0.004	0.996	0.000
S93.4 Sprain and strain of ankle	0.004	0.996	0.000
S93.5 Sprain and strain of toe(s)	0.004	0.996	0.000
N36.9 Urethral disorder, unspecified	0.004	0.996	0.000
S92.3 Fracture of metatarsal bone	0.004	0.996	0.000
S95 Injury of blood vessels at ankle and foot level	0.004	0.996	0.000
S94 Injury of nerves at ankle and foot level	0.004	0.996	0.000
S98 Traumatic amputation of ankle and foot	0.003	0.996	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.004	0.996	0.000
S90 Superficial injury of ankle and foot	0.003	0.996	0.000
S92.11 Fracture of talus (open)	0.003	0.996	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.003	0.997	0.000
R16.1 Splenomegaly, not elsewhere classified	0.000	0.997	0.003
N36 Other disorders of urethra	0.003	0.997	0.000
S22.41 Multiple fractures of ribs (open)	0.000	0.997	0.003
Q54.0 Hypospadias, balanic	0.003	0.997	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.003	0.997	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.003	0.997	0.000
Q54 Hypospadias	0.003	0.997	0.000
Q54.9 Hypospadias, unspecified	0.003	0.997	0.000
S97.1 Crushing injury of toe(s)	0.003	0.997	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.000	0.997	0.003
S92.91 Fracture of foot, unspecified (open)	0.003	0.997	0.000
M13.90 Arthritis, unspecified (Multiple sites)	0.003	0.997	0.000
K56.2 Volvulus	0.003	0.997	0.000
S91.2 Open wound of toe(s) with damage to nail	0.003	0.997	0.000
R16.2 Hepatomegaly with splenomegaly, not elsewhere classified	0.000	0.997	0.003
S91.0 Open wound of ankle	0.003	0.997	0.000
S97.0 Crushing injury of ankle	0.003	0.997	0.000
S90.0 Contusion of ankle	0.003	0.997	0.000
S91.3 Open wound of other parts of foot	0.003	0.997	0.000
G44 Other headache syndromes	0.000	0.997	0.003
N36.3 Prolapsed urethral mucosa	0.003	0.997	0.000
G44.0 Cluster headache syndrome	0.000	0.997	0.003
S22.0 Fracture of thoracic vertebra	0.000	0.997	0.003
S91.7 Multiple open wounds of ankle and foot	0.003	0.997	0.000
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.000	0.997	0.003
S92.21 Fracture of other tarsal bone(s) (open)	0.003	0.997	0.000
S92.90 Fracture of foot, unspecified (closed)	0.003	0.997	0.000
S99.9 Unspecified injury of ankle and foot	0.003	0.997	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.000	0.997	0.003
G44.1 Vascular headache, not elsewhere classified	0.000	0.997	0.003
S99.8 Other specified injuries of ankle and foot	0.003	0.997	0.000
I20.1 Angina pectoris with documented spasm	0.003	0.997	0.000
S91.1 Open wound of toe(s) without damage to nail	0.003	0.997	0.000
S99.7 Multiple injuries of ankle and foot	0.003	0.997	0.000
I84.4 External haemorrhoids with other complications	0.003	0.997	0.000
S90.8 Other superficial injuries of ankle and foot	0.003	0.997	0.000
S93.40 Sprain of unspecified ligament of ankle	0.003	0.997	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.003	0.997	0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances	0.000	0.997	0.003
S92.31 Fracture of metatarsal bone (open)	0.003	0.997	0.000
M71.2 Synovial cyst of popliteal space [Baker]	0.000	0.997	0.003
S94.9 Injury of unspecified nerve at ankle and foot level	0.003	0.997	0.000
S94.8 Injury of other nerves at ankle and foot level	0.003	0.997	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.003	0.997	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.003	0.997	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.003	0.997	0.000
S94.1 Injury of medial plantar nerve	0.003	0.997	0.000
S94.0 Injury of lateral plantar nerve	0.003	0.997	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.003	0.997	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.003	0.997	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.003	0.997	0.000
S95.2 Injury of dorsal vein of foot	0.003	0.997	0.000
S95.1 Injury of plantar artery of foot	0.003	0.997	0.000
S95.0 Injury of dorsal artery of foot	0.003	0.997	0.000
Z36.0 Antenatal screening for chromosomal anomalies	0.003	0.997	0.000
J35.1 Hypertrophy of tonsils	0.000	0.997	0.003
Q54.1 Hypospadias, penile	0.003	0.997	0.000
S90.1 Contusion of toe(s) without damage to nail	0.003	0.997	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.003	0.997	0.000
S98.3 Traumatic amputation of other parts of foot	0.003	0.997	0.000
S98.2 Traumatic amputation of two or more toes	0.003	0.997	0.000
S98.0 Traumatic amputation of foot at ankle level	0.003	0.997	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.003	0.997	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.003	0.997	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.003	0.997	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.003	0.997	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.003	0.997	0.000
S90.2 Contusion of toe(s) with damage to nail	0.003	0.997	0.000
S98.1 Traumatic amputation of one toe	0.003	0.997	0.000
Z56.6 Other physical and mental strain related to work	0.000	0.997	0.003
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.000	0.997	0.003
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.003	0.997	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.003	0.997	0.000
X41.9 Unspecified place	0.003	0.997	0.000
Q54.8 Other hypospadias	0.003	0.997	0.000
D73.0 Hyposplenism	0.000	0.997	0.003
C90.2 Plasmacytoma, extramedullary	0.003	0.997	0.000
Q54.4 Congenital chordee	0.003	0.997	0.000
Q54.3 Hypospadias, perineal	0.003	0.997	0.000
Q54.2 Hypospadias, penoscrotal	0.003	0.997	0.000
G44.3 Chronic posttraumatic headache	0.000	0.997	0.003
J30.1 Allergic rhinitis due to pollen	0.000	0.997	0.003
S90.3 Contusion of other and unspecified parts of foot	0.002	0.997	0.000
X49.6 Industrial and construction area	0.000	0.997	0.002
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.000	0.997	0.003
Y83.9 Surgical procedure, unspecified	0.000	0.997	0.003
I20 Angina pectoris	0.003	0.997	0.000
S22.01 Fracture of thoracic vertebra (open)	0.000	0.997	0.002
S22.3 Fracture of rib	0.000	0.998	0.002
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.002	0.998	0.000
Q25 Congenital malformations of great arteries	0.002	0.998	0.000
R00.0 Tachycardia, unspecified	0.002	0.998	0.000
S22.9 Fracture of bony thorax, part unspecified	0.000	0.998	0.002
S22.8 Fracture of other parts of bony thorax	0.000	0.998	0.002
S92.20 Fracture of other tarsal bone(s) (closed)	0.002	0.998	0.000
G44.4 Drug-induced headache, not elsewhere classified	0.000	0.998	0.002
C90.3 Solitary plasmacytoma	0.002	0.998	0.000
R16.0 Hepatomegaly, not elsewhere classified	0.000	0.998	0.002
X49.4 Street and highway	0.000	0.998	0.002
X49.0 Home	0.000	0.998	0.002
X49.8 Other specified place	0.000	0.998	0.002
X49.7 Farm	0.000	0.998	0.002
X49.5 Trade and service area	0.000	0.998	0.002
X49.3 Sports and athletics area	0.000	0.998	0.002
X49.2 School, other institution and public administrative area	0.000	0.998	0.002
X49.1 Residential institution	0.000	0.998	0.002
Q50-Q56 Congenital malformations of genital organs	0.002	0.998	0.000
M71.29 Synovial cyst of popliteal space [Baker]-Site unspec	0.000	0.998	0.002
M71.28 Synovial cyst of popliteal space [Baker]-Other	0.000	0.998	0.002
M71.27 Synovial cyst of popliteal space [Baker]-Ankle/Foot	0.000	0.998	0.002
M71.25 Synovial cyst of popliteal space [Baker]-Pelvic/Thigh	0.000	0.998	0.002
M71.24 Synovial cyst of popliteal space [Baker]-Hand	0.000	0.998	0.002
M71.23 Synovial cyst of popliteal space [Baker]-Forearm	0.000	0.998	0.002
M71.22 Synovial cyst of popliteal space [Baker]-Upper arm	0.000	0.998	0.002
M71.21 Synovial cyst of popliteal space [Baker]-Shldr region	0.000	0.998	0.002
M71.20 Synovial cyst of popliteal space [Baker]-Mult sites	0.000	0.998	0.002
Z97.4 Presence of external hearing-aid	0.000	0.998	0.002
S22.1 Multiple fractures of thoracic spine	0.000	0.998	0.002
Q24.5 Malformation of coronary vessels	0.002	0.998	0.000
Q25.4 Other congenital malformations of aorta	0.002	0.998	0.000
S27.3 Other injuries of lung	0.000	0.998	0.002
G44.8 Other specified headache syndromes	0.000	0.998	0.002
Z36 Antenatal screening	0.002	0.998	0.000
N36.1 Urethral diverticulum	0.002	0.998	0.000
N28.0 Ischaemia and infarction of kidney	0.000	0.998	0.002
Q25.0 Patent ductus arteriosus	0.002	0.998	0.000
C90.1 Plasma cell leukaemia	0.002	0.998	0.000
Q66 Congenital deformities of feet	0.002	0.998	0.000
Q25.3 Stenosis of aorta	0.002	0.998	0.000
S22.5 Flail chest	0.000	0.998	0.002
Q55 Other congenital malformations of male genital organs	0.002	0.998	0.000
Q53 Undescended testicle	0.002	0.998	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.002	0.998	0.000
Q25.1 Coarctation of aorta	0.002	0.998	0.000
Q66.0 Talipes equinovarus	0.002	0.998	0.000
N75.1 Abscess of Bartholin's gland	0.000	0.998	0.002
S92.30 Fracture of metatarsal bone (closed)	0.002	0.998	0.000
S01.0 Open wound of scalp	0.002	0.998	0.000
S27 Injury of other and unspecified intrathoracic organs	0.000	0.998	0.002
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.002	0.998	0.000
Q66.9 Congenital deformity of feet, unspecified	0.002	0.998	0.000
S22.31 Fracture of rib (open)	0.000	0.998	0.002
Q25.6 Stenosis of pulmonary artery	0.002	0.998	0.000
Q52 Other congenital malformations of female genitalia	0.002	0.998	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.002	0.998	0.000
S22.30 Fracture of rib (closed)	0.000	0.998	0.002
Q25.9 Congenital malformation of great arteries, unspecified	0.002	0.998	0.000
Q25.8 Other congenital malformations of great arteries	0.002	0.998	0.000
Q25.5 Atresia of pulmonary artery	0.002	0.998	0.000
Q25.2 Atresia of aorta	0.002	0.998	0.000
R00.8 Other and unspecified abnormalities of heart beat	0.002	0.998	0.000
S22.81 Fracture of other parts of bony thorax (open)	0.000	0.998	0.002
S22.80 Fracture of other parts of bony thorax (closed)	0.000	0.998	0.002
S22.91 Fracture of bony thorax, part unspecified (open)	0.000	0.998	0.002
S22.90 Fracture of bony thorax, part unspecified (closed)	0.000	0.998	0.002
Q18 Other congenital malformations of face and neck	0.002	0.998	0.000
Q18.0 Sinus, fistula and cyst of branchial cleft	0.002	0.998	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.002	0.998	0.000
X49.09 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances; Home; During unspecified activity	0.000	0.998	0.002
X49.48 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances; Street and highway;While engaged in other specified activities	0.000	0.998	0.002
Q53.2 Undescended testicle, bilateral	0.002	0.998	0.000
S27.2 Traumatic heamopneumothorax	0.000	0.998	0.002
Q66.3 Other congenital varus deformities of feet	0.002	0.998	0.000
Q89.2 Congenital malformations of other endocrine glands	0.000	0.998	0.002
S27.0 Traumatic pneumothorax	0.000	0.998	0.002
Q24 Other congenital malformations of heart	0.002	0.998	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.002	0.998	0.000
S22.11 Multiple fractures of thoracic spine (open)	0.000	0.998	0.002
Q53.1 Undescended testicle, unilateral	0.002	0.998	0.000
S27.31 Other injuries of lung (with open wound into thoracic cavity)	0.000	0.998	0.002
N34.3 Urethral syndrome, unspecified	0.000	0.998	0.002
Q23.0 Congenital stenosis of aortic valve	0.002	0.998	0.000
Q23 Congenital malformations of aortic and mitral valves	0.002	0.998	0.000
Q55.0 Absence and aplasia of testis	0.002	0.998	0.000
Q66.6 Other congenital valgus deformities of feet	0.002	0.998	0.000
Z36.5 Antenatal screening for isoimmunisation	0.002	0.998	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.000	0.998	0.002
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.000	0.998	0.002
Q18.1 Preauricular sinus and cyst	0.002	0.998	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.002	0.998	0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.002	0.998	0.000
Q55.2 Other congenital malformations of testis and scrotum	0.002	0.998	0.000
S22.2 Fracture of sternum	0.000	0.998	0.002
S90.9 Superficial injury of ankle and foot, unspecified	0.002	0.998	0.000
Q28 Other congenital malformations of circulatory system	0.002	0.998	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.002	0.998	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.002	0.998	0.000
Q55.6 Other congenital malformations of penis	0.002	0.998	0.000
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.000	0.998	0.002
Q66.5 Congenital pes planus	0.002	0.998	0.000
Q66.4 Talipes calcaneovalgus	0.002	0.998	0.000
Q66.1 Talipes calcaneovarus	0.002	0.998	0.000
R45.2 Unhappiness	0.002	0.998	0.000
R45.0 Nervousness	0.002	0.998	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.002	0.998	0.000
S22.51 Flail chest (open)	0.000	0.998	0.002
Q52.4 Other congenital malformations of vagina	0.002	0.998	0.000
Q55.9 Congenital malformation of male genital organ, unspecified	0.002	0.998	0.000
Q55.8 Other specified congenital malformations of male genital organs	0.002	0.998	0.000
Q55.5 Congenital absence and aplasia of penis	0.002	0.998	0.000
Q55.3 Atresia of vas deferens	0.002	0.998	0.000
Q55.1 Hypoplasia of testis and scrotum	0.002	0.998	0.000
Q53.0 Ectopic testis	0.002	0.998	0.000
Q66.2 Metatarsus varus	0.002	0.998	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.000	0.998	0.002
D47.4 Osteomyelofibrosis	0.000	0.998	0.002
Q24.8 Other specified congenital malformations of heart	0.002	0.998	0.000
Q66.7 Pes cavus	0.002	0.998	0.000
D47.1 Chronic myeloproliferative disease	0.000	0.998	0.002
Q52.5 Fusion of labia	0.002	0.998	0.000
Z36.1 Antenatal screening for raised alphafetoprotein level	0.002	0.998	0.000
Z89.5 Acquired absence of leg at or below knee	0.002	0.998	0.000
M81.20 Osteoporosis of disuse (Multiple sites)	0.000	0.998	0.002
O69.2 Labour and delivery complicated by other cord entanglement	0.000	0.998	0.002
Q28.2 Arteriovenous malformation of cerebral vessels	0.002	0.998	0.000
Q53.9 Undescended testicle, unspecified	0.002	0.998	0.000
Q67.5 Congenital deformity of spine	0.002	0.998	0.000
S27.9 Injury of unspecified intrathoracic organ	0.000	0.998	0.002
S27.7 Multiple injuries of intrathoracic organs	0.000	0.998	0.002
S27.6 Injury of pleura	0.000	0.998	0.002
S27.5 Injury of thoracic trachea	0.000	0.998	0.002
S27.4 Injury of bronchus	0.000	0.998	0.002
C48.0 Retroperitoneum	0.002	0.998	0.000
N92.5 Other specified irregular menstruation	0.000	0.998	0.002
Q16 Congenital malformations of ear causing impairment of hearing	0.002	0.998	0.000
Q26 Congenital malformations of great veins	0.002	0.998	0.000
Q68 Other congenital musculoskeletal deformities	0.002	0.998	0.000
I44.2 Atrioventricular block, complete	0.002	0.998	0.000
K75.9 Inflammatory liver disease, unspecified	0.000	0.998	0.002
M53.3 Sacrococcygeal disorders, not elsewhere classified	0.002	0.998	0.000
Q52.9 Congenital malformation of female genitalia, unspecified	0.002	0.998	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.002	0.998	0.000
Q52.7 Other congenital malformations of vulva	0.002	0.998	0.000
Q52.6 Congenital malformation of clitoris	0.002	0.998	0.000
Q52.3 Imperforate hymen	0.002	0.998	0.000
Q52.2 Congenital rectovaginal fistula	0.002	0.998	0.000
Q52.0 Congenital absence of vagina	0.002	0.998	0.000
R40.2 Coma, unspecified	0.002	0.998	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.002	0.998	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.002	0.998	0.000
Q70 Syndactyly	0.002	0.998	0.000
C22.1 Intrahepatic bile duct carcinoma	0.002	0.998	0.000
Q18.9 Congenital malformation of face and neck, unspecified	0.002	0.998	0.000
Q18.8 Other specified congenital malformations of face and neck	0.002	0.998	0.000
Q18.7 Microcheilia	0.002	0.998	0.000
Q18.6 Macrocheilia	0.002	0.998	0.000
Q18.5 Microstomia	0.002	0.998	0.000
Q18.4 Macrostomia	0.002	0.998	0.000
Q18.3 Webbing of neck	0.002	0.998	0.000
Q18.2 Other branchial cleft malformations	0.002	0.998	0.000
Q14 Congenital malformations of posterior segment of eye	0.002	0.998	0.000
Q75 Other congenital malformations of skull and face bones	0.002	0.998	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.002	0.998	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.002	0.998	0.000
D73 Diseases of spleen	0.000	0.998	0.002
S20-S29 Injuries to the thorax	0.000	0.998	0.002
I15.1 Hypertension secondary to other renal disorders	0.002	0.998	0.000
K27.7 Chronic without haemorrhage or perforation	0.000	0.998	0.002
Q28.3 Other malformations of cerebral vessels	0.002	0.998	0.000
Q52.1 Doubling of vagina	0.002	0.998	0.000
Q79.1 Other congenital malformations of diaphragm	0.002	0.998	0.000
Q76 Congenital malformations of spine and bony thorax	0.002	0.998	0.000
Q73 Reduction defects of unspecified limb	0.002	0.998	0.000
Q72 Reduction defects of lower limb	0.002	0.998	0.000
Q71 Reduction defects of upper limb	0.002	0.998	0.000
Q69 Polydactyly	0.002	0.998	0.000
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.000	0.998	0.002
D73.8 Other diseases of spleen	0.000	0.998	0.002
Q16.9 Congenital malformation of ear causing impairment of hearing, unspecified	0.002	0.998	0.000
Q23.1 Congenital insufficiency of aortic valve	0.002	0.998	0.000
Q24.6 Congenital heart block	0.002	0.998	0.000
Q24.4 Congenital subaortic stenosis	0.001	0.998	0.000
Q24.3 Pulmonary infundibular stenosis	0.001	0.998	0.000
Q24.2 Cor triatriatum	0.001	0.998	0.000
Q24.1 Levocardia	0.001	0.998	0.000
Q56.4 Indeterminate sex, unspecified	0.001	0.998	0.000
Q56.3 Pseudohermaphroditism, unspecified	0.001	0.998	0.000
Q56.2 Female pseudohermaphroditism, not elsewhere classified	0.001	0.998	0.000
Q56.1 Male pseudohermaphroditism, not elsewhere classified	0.001	0.998	0.000
Q56.0 Hermaphroditism, not elsewhere classified	0.001	0.998	0.000
Q66.8 Other congenital deformities of feet	0.002	0.998	0.000
Q85.9 Phakomatosis, unspecified	0.002	0.998	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.000	0.998	0.002
D73.4 Cyst of spleen	0.000	0.998	0.002
K61.3 Ischiorectal abscess	0.002	0.998	0.000
O75.8 Other specified complications of labour and delivery	0.000	0.998	0.002
Q82.2 Mastocytosis	0.002	0.998	0.000
Z36.2 Other antenatal screening based on amniocentesis	0.002	0.998	0.000
Z56.3 Stressful work schedule	0.000	0.998	0.002
Q22 Congenital malformations of pulmonary and tricuspid valves	0.002	0.998	0.000
S21 Open wound of thorax	0.000	0.998	0.002
M53.39 Sacrococcygeal disorders, not elsewhere classified-Site uns	0.002	0.998	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.002	0.998	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.002	0.998	0.000
Q23.4 Hypoplastic left heart syndrome	0.002	0.998	0.000
Q23.2 Congenital mitral stenosis	0.002	0.998	0.000
S27.8 Injury of other specified intrathoracic organs	0.000	0.998	0.001
Q17 Other congenital malformations of ear	0.002	0.998	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.002	0.998	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.002	0.998	0.000
S21.2 Open wound of back wall of thorax	0.000	0.998	0.002
Q13 Congenital malformations of anterior segment of eye	0.001	0.998	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.002	0.998	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.002	0.998	0.000
S22.21 Fracture of sternum (open)	0.000	0.998	0.001
M92.6 Juvenile osteochondrosis of tarsus	0.002	0.998	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.001	0.998	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.001	0.998	0.000
Q28.1 Other malformations of precerebral vessels	0.001	0.998	0.000
S27.1 Traumatic haemothorax	0.000	0.998	0.002
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.002	0.998	0.000
N73.9 Female pelvic inflammatory disease, unspecified	0.000	0.998	0.002
Q14.1 Congenital malformation of retina	0.001	0.998	0.000
Q67.8 Other congenital deformities of chest	0.001	0.998	0.000
Q67.7 Pectus carinatum	0.001	0.998	0.000
Q67.3 Plagiocephaly	0.001	0.998	0.000
Q67.2 Dolichocephaly	0.001	0.998	0.000
Q67.1 Compression facies	0.001	0.998	0.000
Q67.0 Facial asymmetry	0.001	0.998	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.001	0.998	0.000
R45.6 Physical violence	0.002	0.998	0.000
S24 Injury of nerves and spinal cord at thorax level	0.000	0.998	0.002
J98.9 Respiratory disorder, unspecified	0.000	0.998	0.002
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.001	0.998	0.000
H60.9 Otitis externa, unspecified	0.000	0.998	0.002
Q77.4 Achondroplasia	0.001	0.998	0.000
K27 Peptic ulcer, site unspecified	0.000	0.998	0.002
Q15 Other congenital malformations of eye	0.001	0.998	0.000
Q65 Congenital deformities of hip	0.002	0.998	0.000
N34.2 Other urethritis	0.000	0.998	0.002
Q27.8 Other specified congenital malformations of peripheral vascular system	0.001	0.998	0.000
Q50.5 Embryonic cyst of broad ligament	0.001	0.998	0.000
Q70.3 Webbed toes	0.001	0.998	0.000
Q12 Congenital lens malformations	0.001	0.998	0.000
Q74 Other congenital malformations of limb(s)	0.001	0.998	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.000	0.998	0.001
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.001	0.998	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.001	0.998	0.000
S22.50 Flail chest (closed)	0.000	0.998	0.001
S27.41 Injury of bronchus (with open wound into thoracic cavity)	0.000	0.998	0.001
S27.40 Injury of bronchus (without open wound into thoracic cavity)	0.000	0.998	0.001
S27.51 Injury of thoracic trachea (with open wound into thoracic cavity)	0.000	0.998	0.001
S27.50 Injury of thoracic trachea (without open wound into thoracic cavity)	0.000	0.998	0.001
S27.61 Injury of pleura (with open wound into thoracic cavity)	0.000	0.998	0.001
S27.60 Injury of pleura (without open wound into thoracic cavity)	0.000	0.998	0.001
S27.71 Multiple injuries of intrathoracic organs (with open wound into thoracic cavity)	0.000	0.998	0.001
S27.70 Multiple injuries of intrathoracic organs (without open wound into thoracic cavity)	0.000	0.998	0.001
S27.91 Injury of unspecified intrathoracic organ (with open wound into thoracic cavity)	0.000	0.998	0.001
S27.90 Injury of unspecified intrathoracic organ (without open wound into thoracic cavity)	0.000	0.998	0.001
D73.9 Disease of spleen, unspecified	0.000	0.998	0.001
Q16.5 Congenital malformation of inner ear	0.001	0.998	0.000
Q16.4 Other congenital malformations of middle ear	0.001	0.998	0.000
Q16.3 Congenital malformation of ear ossicles	0.001	0.998	0.000
Q16.2 Absence of eustachian tube	0.001	0.998	0.000
Q16.1 Congenital absence, atresia and stricture of auditory canal (external)	0.001	0.998	0.000
Q16.0 Congenital absence of (ear) auricle	0.001	0.998	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.001	0.998	0.000
Q75.4 Mandibulofacial dysostosis	0.001	0.998	0.000
S24.1 Other and unspecified injuries of thoracic spinal cord	0.000	0.998	0.001
Z01.5 Diagnostic skin and sensitisation tests	0.000	0.998	0.002
Z81.8 Family history of other mental and behavioural disorders	0.002	0.998	0.000
Q78 Other osteochondrodysplasias	0.001	0.998	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.001	0.998	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.000	0.998	0.002
M53.37 Sacrococcygeal disorders, not elsewhere classified-Lumbosac	0.001	0.998	0.000
M53.36 Sacrococcygeal disorders, not elsewhere classified-Lumbar	0.001	0.998	0.000
M53.35 Sacrococcygeal disorders, not elsewhere classified-Thoracol	0.001	0.998	0.000
M53.34 Sacrococcygeal disorders, not elsewhere classified-Thoracic	0.001	0.998	0.000
M53.33 Sacrococcygeal disorders, not elsewhere classified-Cervicot	0.001	0.998	0.000
M53.32 Sacrococcygeal disorders, not elsewhere classified-Cervical	0.001	0.998	0.000
M53.31 Sacrococcygeal disorders, not elsewhere classified-Occipit-	0.001	0.998	0.000
M53.30 Sacrococcygeal disorders, not elsewhere classified-Mult sit	0.001	0.998	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.001	0.998	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.001	0.998	0.000
Q20.6 Isomerism of atrial appendages	0.001	0.998	0.000
Q20.5 Discordant atrioventricular connexion	0.001	0.998	0.000
Q20.4 Double inlet ventricle	0.001	0.998	0.000
Q20.3 Discordant ventriculoarterial connexion	0.001	0.998	0.000
Q20.2 Double outlet left ventricle	0.001	0.998	0.000
Q20.1 Double outlet right ventricle	0.001	0.998	0.000
Q20.0 Common arterial trunk	0.001	0.998	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.001	0.998	0.000
Q26.8 Other congenital malformations of great veins	0.001	0.998	0.000
Q26.6 Portal vein-hepatic artery fistula	0.001	0.998	0.000
Q26.5 Anomalous portal venous connexion	0.001	0.998	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.001	0.998	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.001	0.998	0.000
Q26.1 Persistent left superior vena cava	0.001	0.998	0.000
Q26.0 Congenital stenosis of vena cava	0.001	0.998	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.001	0.998	0.000
Q68.4 Congenital bowing of tibia and fibula	0.001	0.998	0.000
Q68.3 Congenital bowing of femur	0.001	0.998	0.000
Q68.2 Congenital deformity of knee	0.001	0.998	0.000
Q68.1 Congenital deformity of hand	0.001	0.998	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.001	0.998	0.000
Q70.9 Syndactyly, unspecified	0.001	0.998	0.000
Q70.4 Polysyndactyly	0.001	0.998	0.000
Q70.2 Fused toes	0.001	0.998	0.000
Q70.1 Webbed fingers	0.001	0.998	0.000
Q70.0 Fused fingers	0.001	0.998	0.000
Q76.5 Cervical rib	0.001	0.998	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.001	0.998	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.001	0.998	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.001	0.998	0.000
Q77.6 Chondroectodermal dysplasia	0.001	0.998	0.000
Q77.5 Diastrophic dysplasia	0.001	0.998	0.000
Q77.3 Chondrodysplasia punctata	0.001	0.998	0.000
Q77.2 Short rib syndrome	0.001	0.998	0.000
Q77.1 Thanatophoric short stature	0.001	0.998	0.000
Q77.0 Achondrogenesis	0.001	0.998	0.000
Q89 Other congenital malformations, not elsewhere classified	0.001	0.998	0.001
Z56 Problems related to employment and unemployment	0.000	0.998	0.001
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.001	0.998	0.000
C67.4 Posterior wall of bladder	0.000	0.998	0.002
D73.5 Infarction of spleen	0.000	0.998	0.001
H49.0 Third [oculomotor] nerve palsy	0.002	0.998	0.000
K65.9 Peritonitis, unspecified	0.000	0.998	0.002
Q14.9 Congenital malformation of posterior segment of eye, unspecified	0.001	0.998	0.000
Q14.8 Other congenital malformations of posterior segment of eye	0.001	0.998	0.000
Q14.3 Congenital malformation of choroid	0.001	0.998	0.000
Q14.2 Congenital malformation of optic disk	0.001	0.998	0.000
Q14.0 Congenital malformation of vitreous humour	0.001	0.998	0.000
Q23.3 Congenital mitral insufficiency	0.001	0.998	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.001	0.998	0.000
Q74.1 Congenital malformation of knee	0.001	0.998	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.001	0.998	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.001	0.998	0.000
Q75.5 Oculomandibular dysostosis	0.001	0.998	0.000
Q75.3 Macrocephaly	0.001	0.998	0.000
Q75.2 Hypertelorism	0.001	0.998	0.000
Q75.1 Craniofacial dysostosis	0.001	0.998	0.000
Q75.0 Craniosynostosis	0.001	0.998	0.000
Q76.0 Spina bifida occulta	0.001	0.998	0.000
Z36.9 Antenatal screening, unspecified	0.002	0.998	0.000
C23 Malignant neoplasm of gallbladder	0.002	0.998	0.000
Q27 Other congenital malformations of peripheral vascular system	0.001	0.998	0.000
Q82 Other congenital malformations of skin	0.001	0.998	0.000
D73.3 Abscess of spleen	0.000	0.998	0.001
D73.2 Chronic congestive splenomegaly	0.000	0.998	0.001
M16.7 Other secondary coxarthrosis	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations