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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1256342
log Bayes Factor = 5.11543
Chromosome 1   position 21,876,492  (GRCh37) Explore rs1256342 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
N20.0 Calculus of kidney
1.000 0.000 0.000
N20 Calculus of kidney and ureter
1.000 0.000 0.000
N20.1 Calculus of ureter
0.999 0.001 0.000
N20.2 Calculus of kidney with calculus of ureter
0.956 0.044 0.000
N20.9 Urinary calculus, unspecified
0.766 0.234 0.000
N20-N23 Urolithiasis
0.726 0.274 0.000
N23 Unspecified renal colic
0.649 0.351 0.000
N21 Calculus of lower urinary tract
0.578 0.422 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.521 0.479 0.000
N21.1 Calculus in urethra
0.511 0.489 0.000
M54 Dorsalgia
0.000 0.583 0.417
N21.9 Calculus of lower urinary tract, unspecified
0.415 0.585 0.000
N21.8 Other lower urinary tract calculus
0.415 0.585 0.000
M54.9 Dorsalgia, unspecified
0.000 0.586 0.414
M54.5 Low back pain
0.000 0.590 0.410
M54.96 Dorsalgia, unspecified (Lumbar region)
0.000 0.605 0.395
M54.2 Cervicalgia
0.000 0.607 0.393
M54.56 Low back pain (Lumbar region)
0.000 0.616 0.384
M54.22 Cervicalgia (Cervical region)
0.000 0.620 0.380
M54.6 Pain in thoracic spine
0.000 0.625 0.375
N22.8 Calculus of urinary tract in other diseases classified elsewhere
0.373 0.626 0.000
N22.0 Calculus of urinary tract in schistosomiasis [bilharziasis]
0.373 0.626 0.000
M54.57 Low back pain (Lumbosacral region)
0.000 0.638 0.362
M54.99 Dorsalgia, unspecified (Site unspecified)
0.000 0.643 0.357
M54.4 Lumbago with sciatica
0.000 0.653 0.347
M54.64 Pain in thoracic spine (Thoracic region)
0.000 0.655 0.345
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.000 0.658 0.342
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.000 0.659 0.341
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.000 0.671 0.329
M54.94 Dorsalgia, unspecified (Thoracic region)
0.000 0.676 0.324
M54.55 Low back pain (Thoracolumbar region)
0.000 0.676 0.324
N21.0 Calculus in bladder
0.320 0.680 0.000
M54.0 Panniculitis affecting regions of neck and back
0.000 0.700 0.299
M54.49 Lumbago with sciatica (Site unspecified)
0.000 0.701 0.299
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.000 0.703 0.297
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.000 0.703 0.297
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.000 0.703 0.297
M54.50 Low back pain (Multiple sites in spine)
0.000 0.705 0.295
M54.3 Sciatica
0.000 0.705 0.295
M54.53 Low back pain-Cervicothoracic
0.000 0.706 0.294
M54.52 Low back pain-Cervical
0.000 0.706 0.294
M54.51 Low back pain-Occipit-atl-axl
0.000 0.706 0.294
M54.23 Cervicalgia (Cervicothoracic region)
0.000 0.706 0.293
M54.8 Other dorsalgia
0.000 0.708 0.292
M54.59 Low back pain (Site unspecified)
0.000 0.710 0.290
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.000 0.710 0.290
M54.1 Radiculopathy
0.000 0.716 0.284
M54.28 Cervicalgia-Sacral/sacrococ
0.000 0.718 0.282
M54.27 Cervicalgia-Lumbosacral
0.000 0.718 0.282
M54.26 Cervicalgia-Lumbar
0.000 0.718 0.282
M54.25 Cervicalgia-Thoracolumbar
0.000 0.718 0.282
M54.24 Cervicalgia-Thoracic
0.000 0.718 0.282
M54.21 Cervicalgia (Occipito-atlanto-axial region)
0.000 0.718 0.282
M54.20 Cervicalgia-Mult site
0.000 0.718 0.282
M54.47 Lumbago with sciatica (Lumbosacral region)
0.000 0.720 0.280
M54.54 Low back pain-Thoracic
0.000 0.721 0.279
M54.69 Pain in thoracic spine-Site unspe
0.000 0.731 0.269
M54.68 Pain in thoracic spine-Sacral/sacrococ
0.000 0.731 0.269
M54.67 Pain in thoracic spine-Lumbosacral
0.000 0.731 0.269
M54.66 Pain in thoracic spine-Lumbar
0.000 0.731 0.269
M54.65 Pain in thoracic spine (Thoracolumbar region)
0.000 0.731 0.269
M54.63 Pain in thoracic spine (Cervicothoracic region)
0.000 0.731 0.269
M54.62 Pain in thoracic spine-Cervical
0.000 0.731 0.269
M54.61 Pain in thoracic spine-Occipit-atl-axl
0.000 0.731 0.269
M54.60 Pain in thoracic spine (Multiple sites in spine)
0.000 0.731 0.269
M54.92 Dorsalgia, unspecified (Cervical region)
0.000 0.746 0.254
M54.12 Radiculopathy (Cervical region)
0.000 0.750 0.250
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)
0.000 0.751 0.249
M54.45 Lumbago with sciatica (Thoracolumbar region)
0.000 0.751 0.249
M54.44 Lumbago with sciatica-Thoracic
0.000 0.751 0.249
M54.43 Lumbago with sciatica-Cervicothoracic
0.000 0.751 0.249
M54.42 Lumbago with sciatica-Cervical
0.000 0.751 0.249
M54.41 Lumbago with sciatica-Occipit-atl-axl
0.000 0.751 0.249
M54.40 Lumbago with sciatica (Multiple sites in spine)
0.000 0.751 0.249
M54.39 Sciatica (Site unspecified)
0.000 0.757 0.243
M54.29 Cervicalgia-Site unspe
0.000 0.766 0.233
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.000 0.772 0.228
M54.09 Panniculitis affecting regions of neck and back (Site unspecified)
0.000 0.785 0.215
M54.08 Panniculitis affecting regions of neck and back (Sacral and sacrococcygeal region)
0.000 0.785 0.215
M54.07 Panniculitis affecting regions of neck and back (Lumbosacral region)
0.000 0.785 0.215
M54.06 Panniculitis affecting regions of neck and back (Lumbar region)
0.000 0.785 0.215
M54.05 Panniculitis affecting regions of neck and back (Thoracolumbar region)
0.000 0.785 0.215
M54.04 Panniculitis affecting regions of neck and back (Thoracic region)
0.000 0.785 0.215
M54.03 Panniculitis affecting regions of neck and back (Cervicothoracic region)
0.000 0.785 0.215
M54.02 Panniculitis affecting regions of neck and back (Cervical region)
0.000 0.785 0.215
M54.01 Panniculitis affecting regions of neck and back (Occipito-atlanto-axial region)
0.000 0.785 0.215
M54.00 Panniculitis affecting regions of neck and back (Multiple sites in spine)
0.000 0.785 0.215
M54.37 Sciatica (Lumbosacral region)
0.000 0.785 0.215
M54.35 Sciatica (Thoracolumbar region)
0.000 0.789 0.211
M54.34 Sciatica-Thoracic
0.000 0.789 0.211
M54.33 Sciatica-Cervicothoracic
0.000 0.789 0.211
M54.32 Sciatica-Cervical
0.000 0.789 0.211
M54.31 Sciatica-Occipit-atl-axl
0.000 0.789 0.211
M54.30 Sciatica (Multiple sites in spine)
0.000 0.789 0.211
M54.88 Other dorsalgia (Sacral and sacrococcygeal region)
0.000 0.790 0.209
M54.87 Other dorsalgia (Lumbosacral region)
0.000 0.790 0.209
M54.86 Other dorsalgia (Lumbar region)
0.000 0.790 0.209
M54.85 Other dorsalgia (Thoracolumbar region)
0.000 0.790 0.209
M54.84 Other dorsalgia (Thoracic region)
0.000 0.790 0.209
M54.83 Other dorsalgia (Cervicothoracic region)
0.000 0.790 0.209
M54.82 Other dorsalgia (Cervical region)
0.000 0.790 0.209
M54.81 Other dorsalgia (Occipito-atlanto-axial region)
0.000 0.790 0.209
M54.80 Other dorsalgia (Multiple sites in spine)
0.000 0.790 0.209
M54.19 Radiculopathy (Site unspecified)
0.000 0.791 0.209
M54.18 Radiculopathy (Sacral and sacrococcygeal region)
0.000 0.792 0.208
M54.15 Radiculopathy (Thoracolumbar region)
0.000 0.796 0.204
M54.14 Radiculopathy (Thoracic region)
0.000 0.796 0.204
M54.11 Radiculopathy (Occipito-atlanto-axial region)
0.000 0.796 0.204
M54.10 Radiculopathy (Multiple sites in spine)
0.000 0.796 0.204
M54.89 Other dorsalgia (Site unspecified)
0.000 0.798 0.202
M54.46 Lumbago with sciatica (Lumbar region)
0.000 0.802 0.198
M54.17 Radiculopathy (Lumbosacral region)
0.000 0.821 0.179
M54.16 Radiculopathy (Lumbar region)
0.000 0.835 0.165
M54.13 Radiculopathy (Cervicothoracic region)
0.000 0.842 0.157
M54.36 Sciatica (Lumbar region)
0.000 0.890 0.110
M25.51 Pain in joint (Shoulder region)
0.000 0.896 0.104
M25.5 Pain in joint
0.000 0.898 0.102
M25.53 Pain in joint (Forearm)
0.000 0.899 0.101
M25.55 Pain in joint (Pelvic region and thigh)
0.000 0.907 0.093
M25.54 Pain in joint (Hand)
0.000 0.909 0.091
M25.50 Pain in joint (Multiple sites)
0.000 0.910 0.090
M25.52 Pain in joint (Upper arm)
0.000 0.927 0.073
M25.56 Pain in joint (Lower leg)
0.000 0.929 0.071
M25.58 Pain in joint (Other)
0.000 0.930 0.070
M25.59 Pain in joint (Site unspecified)
0.000 0.934 0.066
M25.57 Pain in joint (Ankle and foot)
0.000 0.958 0.042
M50-M54 Other dorsopathies
0.000 0.966 0.034
M53 Other dorsopathies, not elsewhere classified
0.000 0.977 0.023
M53.9 Dorsopathy, unspecified
0.000 0.983 0.017
M53.8 Other specified dorsopathies
0.000 0.983 0.017
M53.2 Spinal instabilities
0.000 0.983 0.017
M53.1 Cervicobrachial syndrome
0.000 0.983 0.017
M53.0 Cervicocranial syndrome
0.000 0.983 0.017
M53.3 Sacrococcygeal disorders, not elsewhere classified
0.000 0.985 0.015
Y52.1 Calcium-channel blockers
0.014 0.986 0.000
Y52 Agents primarily affecting the cardiovascular system
0.014 0.986 0.000
M53.09 Cervicocranial syndrome-Site unspe
0.000 0.988 0.012
M53.08 Cervicocranial syndrome-Sacral/sacrococ
0.000 0.988 0.012
M53.07 Cervicocranial syndrome-Lumbosacral
0.000 0.988 0.012
M53.06 Cervicocranial syndrome-Lumbar
0.000 0.988 0.012
M53.05 Cervicocranial syndrome-Thoracolumbar
0.000 0.988 0.012
M53.04 Cervicocranial syndrome-Thoracic
0.000 0.988 0.012
M53.03 Cervicocranial syndrome (Cervicothoracic region)
0.000 0.988 0.012
M53.02 Cervicocranial syndrome (Cervical region)
0.000 0.988 0.012
M53.01 Cervicocranial syndrome (Occipito-atlanto-axial region)
0.000 0.988 0.012
M53.00 Cervicocranial syndrome (Multiple sites in spine)
0.000 0.988 0.012
M53.19 Cervicobrachial syndrome-Site unspe
0.000 0.988 0.012
M53.18 Cervicobrachial syndrome-Sacral/sacrococ
0.000 0.988 0.012
M53.17 Cervicobrachial syndrome-Lumbosacral
0.000 0.988 0.012
M53.16 Cervicobrachial syndrome-Lumbar
0.000 0.988 0.012
M53.15 Cervicobrachial syndrome-Thoracolumbar
0.000 0.988 0.012
M53.14 Cervicobrachial syndrome-Thoracic
0.000 0.988 0.012
M53.13 Cervicobrachial syndrome (Cervicothoracic region)
0.000 0.988 0.012
M53.12 Cervicobrachial syndrome (Cervical region)
0.000 0.988 0.012
M53.11 Cervicobrachial syndrome (Occipito-atlanto-axial region)
0.000 0.988 0.012
M53.10 Cervicobrachial syndrome (Multiple sites in spine)
0.000 0.988 0.012
M53.29 Spinal instabilities (Site unspecified)
0.000 0.988 0.012
M53.28 Spinal instabilities (Sacral and sacrococcygeal region)
0.000 0.988 0.012
M53.27 Spinal instabilities (Lumbosacral region)
0.000 0.988 0.012
M53.26 Spinal instabilities (Lumbar region)
0.000 0.988 0.012
M53.25 Spinal instabilities (Thoracolumbar region)
0.000 0.988 0.012
M53.24 Spinal instabilities (Thoracic region)
0.000 0.988 0.012
M53.23 Spinal instabilities (Cervicothoracic region)
0.000 0.988 0.012
M53.22 Spinal instabilities (Cervical region)
0.000 0.988 0.012
M53.21 Spinal instabilities (Occipito-atlanto-axial region)
0.000 0.988 0.012
M53.20 Spinal instabilities (Multiple sites in spine)
0.000 0.988 0.012
M53.89 Other specified dorsopathies (Site unspecified)
0.000 0.988 0.012
M53.88 Other specified dorsopathies (Sacral and sacrococcygeal region)
0.000 0.988 0.012
M53.87 Other specified dorsopathies (Lumbosacral region)
0.000 0.988 0.012
M53.86 Other specified dorsopathies (Lumbar region)
0.000 0.988 0.012
M53.85 Other specified dorsopathies (Thoracolumbar region)
0.000 0.988 0.012
M53.84 Other specified dorsopathies (Thoracic region)
0.000 0.988 0.012
M53.83 Other specified dorsopathies (Cervicothoracic region)
0.000 0.988 0.012
M53.82 Other specified dorsopathies (Cervical region)
0.000 0.988 0.012
M53.81 Other specified dorsopathies (Occipito-atlanto-axial region)
0.000 0.988 0.012
M53.80 Other specified dorsopathies (Multiple sites in spine)
0.000 0.988 0.012
M53.99 Dorsopathy, unspecified (Site unspecified)
0.000 0.988 0.012
M53.98 Dorsopathy, unspecified (Sacral and sacrococcygeal region)
0.000 0.988 0.012
M53.97 Dorsopathy, unspecified (Lumbosacral region)
0.000 0.988 0.012
M53.96 Dorsopathy, unspecified (Lumbar region)
0.000 0.988 0.012
M53.95 Dorsopathy, unspecified (Thoracolumbar region)
0.000 0.988 0.012
M53.94 Dorsopathy, unspecified (Thoracic region)
0.000 0.988 0.012
M53.93 Dorsopathy, unspecified (Cervicothoracic region)
0.000 0.988 0.012
M53.92 Dorsopathy, unspecified (Cervical region)
0.000 0.988 0.012
M53.91 Dorsopathy, unspecified (Occipito-atlanto-axial region)
0.000 0.988 0.012
M53.90 Dorsopathy, unspecified (Multiple sites in spine)
0.000 0.988 0.012
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.012 0.988 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.012 0.988 0.000
K83.0 Cholangitis
0.011 0.989 0.000
M53.39 Sacrococcygeal disorders, not elsewhere classified-Site uns
0.000 0.989 0.011
M53.37 Sacrococcygeal disorders, not elsewhere classified-Lumbosac
0.000 0.989 0.011
M53.36 Sacrococcygeal disorders, not elsewhere classified-Lumbar
0.000 0.989 0.011
M53.35 Sacrococcygeal disorders, not elsewhere classified-Thoracol
0.000 0.989 0.011
M53.34 Sacrococcygeal disorders, not elsewhere classified-Thoracic
0.000 0.989 0.011
M53.33 Sacrococcygeal disorders, not elsewhere classified-Cervicot
0.000 0.989 0.011
M53.32 Sacrococcygeal disorders, not elsewhere classified-Cervical
0.000 0.989 0.011
M53.31 Sacrococcygeal disorders, not elsewhere classified-Occipit-
0.000 0.989 0.011
M53.30 Sacrococcygeal disorders, not elsewhere classified-Mult sit
0.000 0.989 0.011
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.011 0.989 0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system
0.011 0.989 0.000
Y52.8 Antivaricose drugs, including sclerosing agents
0.010 0.990 0.000
Y52.7 Peripheral vasodilators
0.010 0.990 0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action
0.010 0.990 0.000
Y44 Agents primarily affecting blood constituents
0.010 0.990 0.000
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s
0.000 0.990 0.010
M51 Other intervertebral disk disorders
0.000 0.990 0.010
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.010 0.990 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.010 0.990 0.000
Y44.2 Anticoagulants
0.010 0.990 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.009 0.991 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.009 0.991 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.009 0.991 0.000
Y44.5 Thrombolytic drugs
0.008 0.991 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.008 0.991 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.008 0.992 0.000
M51.9 Intervertebral disk disorder, unspecified
0.000 0.992 0.008
Y49.0 Tricyclic and tetracyclic antidepressants
0.008 0.992 0.000
H66.9 Otitis media, unspecified
0.000 0.992 0.008
G81.9 Hemiplegia, unspecified
0.008 0.992 0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system
0.008 0.992 0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations
0.008 0.992 0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.008 0.992 0.000
Y46.4 Iminostilbenes
0.007 0.992 0.000
Y46.6 Other and unspecified antiepileptics
0.007 0.992 0.000
Y58 Bacterial vaccines
0.007 0.993 0.000
Y44.9 Other and unspecified agents affecting blood constituents
0.007 0.993 0.000
Y44.7 Plasma substitutes
0.007 0.993 0.000
Y44.6 Natural blood and blood products
0.007 0.993 0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]
0.007 0.993 0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants
0.007 0.993 0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations
0.007 0.993 0.000
M51.4 Schmorl's nodes
0.000 0.993 0.007
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.000 0.993 0.007
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.007 0.993 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.007 0.993 0.000
Y46.2 Hydantoin derivatives
0.007 0.993 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.007 0.993 0.000
Y59 Other and unspecified vaccines and biological substances
0.007 0.993 0.000
H54.4 Blindness, one eye
0.007 0.993 0.000
Y48 Anaesthetics and therapeutic gases
0.007 0.993 0.000
Y49.2 Other and unspecified antidepressants
0.007 0.993 0.000
Y57 Other and unspecified drugs and medicaments
0.007 0.993 0.000
M51.3 Other specified intervertebral disk degeneration
0.000 0.993 0.007
Y46.8 Antispasticity drugs
0.007 0.993 0.000
Y46.7 Anti-Parkinsonism drugs
0.007 0.993 0.000
Y46.5 Valproic acid
0.007 0.993 0.000
Y46.3 Deoxybarbiturates
0.007 0.993 0.000
Y46.1 Oxazolidinediones
0.007 0.993 0.000
Y46.0 Succinimides
0.007 0.993 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.007 0.993 0.000
Y49.9 Psychotropic drug, unspecified
0.006 0.993 0.000
Y49.8 Other psychotropic drugs, not elsewhere classified
0.006 0.993 0.000
Y49.7 Psychostimulants with abuse potential
0.006 0.993 0.000
Y49.6 Psychodysleptics [hallucinogens]
0.006 0.993 0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics
0.006 0.993 0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics
0.006 0.993 0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants
0.006 0.993 0.000
H54.9 Unspecified visual impairment (binocular)
0.007 0.993 0.000
N31.8 Other neuromuscular dysfunction of bladder
0.007 0.993 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.006 0.993 0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified
0.006 0.994 0.000
Y40 Systemic antibiotics
0.006 0.994 0.000
Y56.9 Topical agent, unspecified
0.006 0.994 0.000
Y56.8 Other topical agents
0.006 0.994 0.000
Y56.7 Dental drugs, topically applied
0.006 0.994 0.000
Y56.6 Otorhinolaryngological drugs and preparations
0.006 0.994 0.000
Y56.5 Ophthalmological drugs and preparations
0.006 0.994 0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.006 0.994 0.000
Y56.3 Emollients, demulcents and protectants
0.006 0.994 0.000
Y56.2 Local astringents and local detergents
0.006 0.994 0.000
Y56.1 Antipruritics
0.006 0.994 0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.006 0.994 0.000
Y53.7 Emetics
0.006 0.994 0.000
Y53.6 Antidiarrhoeal drugs
0.006 0.994 0.000
Y53.5 Digestants
0.006 0.994 0.000
Y53.3 Saline and osmotic laxatives
0.006 0.994 0.000
Y53.2 Stimulant laxatives
0.006 0.994 0.000
Y53.1 Other antacids and anti-gastric-secretion drugs
0.006 0.994 0.000
Y53.0 Histamine H2-receptor antagonists
0.006 0.994 0.000
H54 Blindness and low vision
0.006 0.994 0.000
Y42.7 Androgens and anabolic congeners
0.006 0.994 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.006 0.994 0.000
Y53.4 Other laxatives
0.006 0.994 0.000
G35 Multiple sclerosis
0.000 0.994 0.006
M25 Other joint disorders, not elsewhere classified
0.000 0.994 0.006
M50 Cervical disk disorders
0.000 0.994 0.006
Z46.6 Fitting and adjustment of urinary device
0.006 0.994 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.006 0.994 0.000
Y40.7 Antifungal antibiotics, systemically used
0.006 0.994 0.000
Y58.0 BCG vaccine
0.006 0.994 0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system
0.006 0.994 0.000
H54.7 Unspecified visual loss
0.006 0.994 0.000
M51.8 Other specified intervertebral disk disorders
0.000 0.994 0.006
Y40.6 Rifamycins
0.006 0.994 0.000
Y58.9 Other and unspecified bacterial vaccines
0.005 0.994 0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component
0.005 0.994 0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component
0.005 0.994 0.000
Y58.5 Diphtheria vaccine
0.005 0.994 0.000
Y58.4 Tetanus vaccine
0.005 0.994 0.000
Y58.3 Plague vaccine
0.005 0.994 0.000
Y58.2 Cholera vaccine
0.005 0.994 0.000
Y58.1 Typhoid and paratyphoid vaccine
0.005 0.994 0.000
M51.19 Lumbar and other intervertebral disc disorders with radiculopathy; site unspecified
0.000 0.994 0.005
M51.16 Intervertebral disc disorders w radiculopathy, lumbar region
0.000 0.994 0.005
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.000 0.994 0.005
Y50.9 Central nervous system stimulant, unspecified
0.005 0.994 0.000
Y50.8 Other central nervous system stimulants
0.005 0.994 0.000
Y50.2 Methylxanthines, not elsewhere classified
0.005 0.994 0.000
Y50.1 Opioid receptor antagonists
0.005 0.994 0.000
Y50.0 Analeptics
0.005 0.994 0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system
0.005 0.994 0.000
Y55.6 Antiasthmatics, not elsewhere classified
0.005 0.994 0.000
Y55.5 Anticommon cold drugs
0.005 0.994 0.000
Y55.4 Expectorants
0.005 0.994 0.000
Y55.3 Antitussives
0.005 0.994 0.000
Y55.2 Other and unspecified agents primarily acting on muscles
0.005 0.994 0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.005 0.994 0.000
Y55.0 Oxytocic drugs
0.005 0.994 0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified
0.005 0.994 0.000
I24.8 Other forms of acute ischaemic heart disease
0.005 0.995 0.000
Y49.5 Other antipsychotics and neuroleptics
0.005 0.995 0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified
0.005 0.995 0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.005 0.995 0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.005 0.995 0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified
0.005 0.995 0.000
Y51.1 Other parasympathomimetics [cholinergics]
0.005 0.995 0.000
Y51.0 Anticholinesterase agents
0.005 0.995 0.000
Y59.9 Vaccine or biological substance, unspecified
0.005 0.995 0.000
Y59.8 Other specified vaccines and biological substances
0.005 0.995 0.000
Y59.2 Protozoal vaccines
0.005 0.995 0.000
Y59.1 Rickettsial vaccines
0.005 0.995 0.000
Y59.0 Viral vaccines
0.005 0.995 0.000
Y57.9 Drug or medicament, unspecified
0.005 0.995 0.000
N90.9 Noninflammatory disorder of vulva and perineum, unspecified
0.000 0.995 0.005
Y57.8 Other drugs and medicaments
0.005 0.995 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.005 0.995 0.000
Y40.1 Cefalosporins and other -lactam antibiotics
0.005 0.995 0.000
Y57.6 Other diagnostic agents
0.005 0.995 0.000
Y48.5 Therapeutic gases
0.005 0.995 0.000
Y48.1 Parenteral anaesthetics
0.005 0.995 0.000
Y48.0 Inhaled anaesthetics
0.005 0.995 0.000
Y59.3 Immunoglobulin
0.005 0.995 0.000
H54.6 Unqualified visual loss, one eye
0.005 0.995 0.000
Y57.7 Vitamins, not elsewhere classified
0.005 0.995 0.000
Y57.4 Pharmaceutical excipients
0.005 0.995 0.000
Y57.3 Alcohol deterrents
0.005 0.995 0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified
0.005 0.995 0.000
Y57.1 Lipotropic drugs
0.005 0.995 0.000
Y57.0 Appetite depressants [anorectics]
0.005 0.995 0.000
Y48.2 Other and unspecified general anaesthetics
0.005 0.995 0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]
0.005 0.995 0.000
Y48.3 Local anaesthetics
0.005 0.995 0.000
C78.0 Secondary malignant neoplasm of lung
0.000 0.995 0.005
M50.9 Cervical disk disorder, unspecified
0.000 0.995 0.005
Y54.9 Mineral salts, not elsewhere classified
0.005 0.995 0.000
Y54.7 Agents affecting calcification
0.005 0.995 0.000
Y54.6 Electrolytic, caloric and water-balance agents
0.005 0.995 0.000
Y54.5 Other diuretics
0.005 0.995 0.000
Y54.2 Carbonic-anhydrase inhibitors
0.005 0.995 0.000
Y54.0 Mineralocorticoids
0.005 0.995 0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified
0.005 0.995 0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs
0.005 0.995 0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified
0.005 0.995 0.000
Y47.4 Bromine compounds
0.005 0.995 0.000
Y47.3 Paraldehyde
0.005 0.995 0.000
Y47.2 Chloral derivatives
0.005 0.995 0.000
Y47.0 Barbiturates, not elsewhere classified
0.005 0.995 0.000
Y42.2 Antithyroid drugs
0.005 0.995 0.000
Y54.4 Loop [high-ceiling] diuretics
0.005 0.995 0.000
M25.74 Osteophyte (Hand)
0.000 0.995 0.005
H54.1 Blindness, one eye, low vision, other eye
0.005 0.995 0.000
Y40.5 Aminoglycosides
0.005 0.995 0.000
Y40.4 Tetracyclines
0.005 0.995 0.000
Y40.2 Chloramphenicol group
0.005 0.995 0.000
Y48.4 Anaesthetic, unspecified
0.005 0.995 0.000
H54.5 Low vision, one eye
0.005 0.995 0.000
H54.3 Unqualified visual loss, both eyes
0.005 0.995 0.000
H54.2 Low vision, both eyes
0.005 0.995 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.000 0.995 0.005
M25.7 Osteophyte
0.000 0.995 0.005
Y42.9 Other and unspecified hormone antagonists
0.005 0.995 0.000
Y42.4 Oral contraceptives
0.005 0.995 0.000
Y42.1 Thyroid hormones and substitutes
0.005 0.995 0.000
J00 Acute nasopharyngitis [common cold]
0.005 0.995 0.000
Y40.0 Penicillins
0.005 0.995 0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum
0.000 0.995 0.005
N90.5 Atrophy of vulva
0.000 0.995 0.005
Y54.8 Agents affecting uric acid metabolism
0.005 0.995 0.000
M51.37 Other intervertebral disc degeneration, lumbosacral region
0.000 0.995 0.004
M25.2 Flail joint
0.000 0.995 0.004
M25.1 Fistula of joint
0.000 0.995 0.004
Y45.8 Other analgesics and antipyretics
0.005 0.995 0.000
G81 Hemiplegia
0.005 0.995 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.004 0.995 0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified
0.004 0.995 0.000
Y41.4 Anthelminthics
0.004 0.995 0.000
Y41.3 Other antiprotozoal drugs
0.004 0.995 0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa
0.004 0.995 0.000
Y41.1 Antimycobacterial drugs
0.004 0.995 0.000
Y41.0 Sulphonamides
0.004 0.995 0.000
Y41.5 Antiviral drugs
0.004 0.995 0.000
M25.76 Osteophyte (Lower leg)
0.000 0.996 0.004
M25.77 Osteophyte (Ankle and foot)
0.000 0.996 0.004
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.004 0.996 0.000
M25.3 Other instability of joint
0.000 0.996 0.004
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.004 0.996 0.000
Y54.3 Benzothiadiazine derivatives
0.004 0.996 0.000
M50.8 Other cervical disk disorders
0.000 0.996 0.004
C45.0 Mesothelioma of pleura
0.004 0.996 0.000
Y57.5 X-ray contrast media
0.004 0.996 0.000
H54.0 Blindness, both eyes
0.004 0.996 0.000
Y45.1 Salicylates
0.004 0.996 0.000
Y47.1 Benzodiazepines
0.004 0.996 0.000
I73.0 Raynaud's syndrome
0.000 0.996 0.004
N90.6 Hypertrophy of vulva
0.000 0.996 0.004
Y45.5 4-Aminophenol derivatives
0.004 0.996 0.000
M25.0 Haemarthrosis
0.000 0.996 0.004
M50.2 Other cervical disk displacement
0.000 0.996 0.004
Y45.4 Antirheumatics
0.004 0.996 0.000
C45.9 Mesothelioma, unspecified
0.004 0.996 0.000
G81.1 Spastic hemiplegia
0.004 0.996 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.004 0.996 0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm
0.004 0.996 0.000
Y40.3 Macrolides
0.004 0.996 0.000
C45 Mesothelioma
0.004 0.996 0.000
N90.3 Dysplasia of vulva, unspecified
0.000 0.996 0.004
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.004 0.996 0.000
M25.9 Joint disorder, unspecified
0.000 0.996 0.004
N90.7 Vulvar cyst
0.000 0.996 0.004
Y43 Primarily systemic agents
0.004 0.996 0.000
F05.9 Delirium, unspecified
0.004 0.996 0.000
H66 Suppurative and unspecified otitis media
0.000 0.996 0.004
K83 Other diseases of biliary tract
0.004 0.996 0.000
K83.9 Disease of biliary tract, unspecified
0.004 0.996 0.000
N90.2 Severe vulvar dysplasia, not elsewhere classified
0.000 0.996 0.004
N90.0 Mild vulvar dysplasia
0.000 0.996 0.004
M25.73 Osteophyte (Forearm)
0.000 0.996 0.004
M25.70 Osteophyte (Multiple sites)
0.000 0.996 0.004
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.000 0.996 0.004
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.004 0.996 0.000
N90.1 Moderate vulvar dysplasia
0.000 0.996 0.003
M25.19 Fistula of joint (Site unspecified)
0.000 0.996 0.003
M25.18 Fistula of joint (Other)
0.000 0.996 0.003
M25.17 Fistula of joint (Ankle and foot)
0.000 0.996 0.003
M25.16 Fistula of joint (Lower leg)
0.000 0.996 0.003
M25.15 Fistula of joint (Pelvic region and thigh)
0.000 0.996 0.003
M25.14 Fistula of joint (Hand)
0.000 0.996 0.003
M25.13 Fistula of joint (Forearm)
0.000 0.996 0.003
M25.12 Fistula of joint (Upper arm)
0.000 0.996 0.003
M25.11 Fistula of joint (Shoulder region)
0.000 0.996 0.003
M25.10 Fistula of joint (Multiple sites)
0.000 0.996 0.003
M25.29 Flail joint (Site unspecified)
0.000 0.996 0.003
M25.28 Flail joint (Other)
0.000 0.996 0.003
M25.27 Flail joint (Ankle and foot)
0.000 0.996 0.003
M25.26 Flail joint (Lower leg)
0.000 0.996 0.003
M25.25 Flail joint (Pelvic region and thigh)
0.000 0.996 0.003
M25.24 Flail joint (Hand)
0.000 0.996 0.003
M25.23 Flail joint (Forearm)
0.000 0.996 0.003
M25.22 Flail joint (Upper arm)
0.000 0.996 0.003
M25.21 Flail joint (Shoulder region)
0.000 0.996 0.003
M25.20 Flail joint (Multiple sites)
0.000 0.996 0.003
G81.0 Flaccid hemiplegia
0.003 0.996 0.000
L73.9 Follicular disorder, unspecified
0.000 0.996 0.004
M25.31 Other instability of joint (Shoulder region)
0.000 0.996 0.003
R94.3 Abnormal results of cardiovascular function studies
0.000 0.996 0.004
C45.7 Mesothelioma of other sites
0.003 0.996 0.000
Y83.4 Other reconstructive surgery
0.004 0.996 0.000
M25.36 Other instability of joint (Lower leg)
0.000 0.997 0.003
Y40.8 Other systemic antibiotics
0.003 0.997 0.000
M25.4 Effusion of joint
0.000 0.997 0.003
G96.0 Cerebrospinal fluid leak
0.000 0.997 0.003
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.000 0.997 0.003
M25.39 Other instability of joint (Site unspecified)
0.000 0.997 0.003
M25.38 Other instability of joint (Other)
0.000 0.997 0.003
M25.35 Other instability of joint (Pelvic region and thigh)
0.000 0.997 0.003
M25.32 Other instability of joint (Upper arm)
0.000 0.997 0.003
M25.30 Other instability of joint (Multiple sites)
0.000 0.997 0.003
Y43.1 Antineoplastic antimetabolites
0.003 0.997 0.000
Y45.2 Propionic acid derivatives
0.003 0.997 0.000
M25.79 Osteophyte (Site unspecified)
0.000 0.997 0.003
Y42.5 Other oestrogens and progestogens
0.003 0.997 0.000
M25.09 Haemarthrosis (Site unspecified)
0.000 0.997 0.003
M25.08 Haemarthrosis (Other)
0.000 0.997 0.003
M25.07 Haemarthrosis (Ankle and foot)
0.000 0.997 0.003
M25.05 Haemarthrosis (Pelvic region and thigh)
0.000 0.997 0.003
M25.04 Haemarthrosis (Hand)
0.000 0.997 0.003
M25.03 Haemarthrosis (Forearm)
0.000 0.997 0.003
M25.02 Haemarthrosis (Upper arm)
0.000 0.997 0.003
M25.01 Haemarthrosis (Shoulder region)
0.000 0.997 0.003
M25.00 Haemarthrosis (Multiple sites)
0.000 0.997 0.003
M25.37 Other instability of joint (Ankle and foot)
0.000 0.997 0.003
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.003 0.997 0.000
K36 Other appendicitis
0.000 0.997 0.003
M50.0 Cervical disk disorder with myelopathy
0.000 0.997 0.003
M25.8 Other specified joint disorders
0.000 0.997 0.003
R12 Heartburn
0.000 0.997 0.003
M25.33 Other instability of joint (Forearm)
0.000 0.997 0.003
S62.61 Fracture of other finger (open)
0.003 0.997 0.000
C18.2 Ascending colon
0.000 0.997 0.003
C45.2 Mesothelioma of pericardium
0.003 0.997 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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