TreeWAS – Variant ID: rs12564445

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M24.16 Other articular cartilage disorders (Lower leg)	0.078	0.922	0.000
M24.1 Other articular cartilage disorders	0.078	0.922	0.000
M24 Other specific joint derangements	0.073	0.927	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.070	0.930	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.067	0.933	0.000
M24.2 Disorder of ligament	0.065	0.935	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.064	0.936	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.063	0.937	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.063	0.937	0.000
M24.6 Ankylosis of joint	0.061	0.939	0.000
M24.7 Protrusio acetabuli	0.058	0.941	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.057	0.942	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.056	0.944	0.000
M24.18 Other articular cartilage disorders (Other)	0.056	0.944	0.000
M24.14 Other articular cartilage disorders (Hand)	0.056	0.944	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.056	0.944	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.056	0.944	0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.056	0.944	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.055	0.945	0.000
M24.28 Disorder of ligament (Other)	0.055	0.945	0.000
M24.23 Disorder of ligament (Forearm)	0.054	0.946	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.054	0.946	0.000
M24.9 Joint derangement, unspecified	0.052	0.948	0.000
M24.5 Contracture of joint	0.052	0.948	0.000
M24.21 Disorder of ligament (Shoulder region)	0.052	0.948	0.000
M24.26 Disorder of ligament (Lower leg)	0.051	0.949	0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.050	0.950	0.000
M24.67 Ankylosis of joint (Ankle and foot)	0.049	0.951	0.000
M24.75 Protrusio acetabuli-Pelvic/thigh	0.048	0.952	0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.048	0.952	0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.048	0.952	0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.048	0.952	0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.048	0.952	0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.048	0.952	0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.048	0.952	0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.048	0.952	0.000
M24.29 Disorder of ligament (Site unspecified)	0.047	0.953	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.047	0.953	0.000
M24.22 Disorder of ligament (Upper arm)	0.047	0.953	0.000
M24.20 Disorder of ligament (Multiple sites)	0.047	0.953	0.000
M24.66 Ankylosis of joint (Lower leg)	0.046	0.954	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.046	0.954	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.046	0.954	0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.045	0.955	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.045	0.955	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.045	0.955	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.045	0.955	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.045	0.955	0.000
Z88.2 Personal history of allergy to sulphonamides	0.045	0.955	0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.044	0.955	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.044	0.956	0.000
M24.69 Ankylosis of joint (Site unspecified)	0.044	0.956	0.000
M24.68 Ankylosis of joint (Other)	0.044	0.956	0.000
M24.64 Ankylosis of joint (Hand)	0.044	0.956	0.000
M24.63 Ankylosis of joint (Forearm)	0.044	0.956	0.000
M24.62 Ankylosis of joint (Upper arm)	0.044	0.956	0.000
M24.61 Ankylosis of joint (Shoulder region)	0.044	0.956	0.000
M24.60 Ankylosis of joint (Multiple sites)	0.044	0.956	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.044	0.956	0.000
M24.24 Disorder of ligament (Hand)	0.043	0.957	0.000
M24.79 Protrusio acetabuli-Site unspec	0.042	0.958	0.000
M24.78 Protrusio acetabuli-Other	0.042	0.958	0.000
M24.77 Protrusio acetabuli-Ankle/foot	0.042	0.958	0.000
M24.76 Protrusio acetabuli-Lower leg	0.042	0.958	0.000
M24.74 Protrusio acetabuli-Hand	0.042	0.958	0.000
M24.73 Protrusio acetabuli-Forearm	0.042	0.958	0.000
M24.72 Protrusio acetabuli-Upper arm	0.042	0.958	0.000
M24.71 Protrusio acetabuli-Shldr region	0.042	0.958	0.000
M24.70 Protrusio acetabuli-Mult sites	0.042	0.958	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.042	0.958	0.000
M24.54 Contracture of joint (Hand)	0.041	0.959	0.000
M24.0 Loose body in joint	0.041	0.959	0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.040	0.959	0.000
M24.99 Joint derangement, unspecified (Site unspecified)	0.038	0.962	0.000
M24.98 Joint derangement, unspecified (Other)	0.038	0.962	0.000
M24.97 Joint derangement, unspecified (Ankle and foot)	0.038	0.962	0.000
M24.96 Joint derangement, unspecified (Lower leg)	0.038	0.962	0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.038	0.962	0.000
M24.94 Joint derangement, unspecified (Hand)	0.038	0.962	0.000
M24.93 Joint derangement, unspecified (Forearm)	0.038	0.962	0.000
M24.92 Joint derangement, unspecified (Upper arm)	0.038	0.962	0.000
M24.91 Joint derangement, unspecified (Shoulder region)	0.038	0.962	0.000
M24.90 Joint derangement, unspecified (Multiple sites)	0.038	0.962	0.000
M24.59 Contracture of joint (Site unspecified)	0.037	0.963	0.000
M24.58 Contracture of joint (Other)	0.037	0.963	0.000
M24.57 Contracture of joint (Ankle and foot)	0.037	0.963	0.000
M24.55 Contracture of joint (Pelvic region and thigh)	0.037	0.963	0.000
M24.53 Contracture of joint (Forearm)	0.037	0.963	0.000
M24.52 Contracture of joint (Upper arm)	0.037	0.963	0.000
M24.50 Contracture of joint (Multiple sites)	0.037	0.963	0.000
M24.51 Contracture of joint (Shoulder region)	0.034	0.965	0.000
M24.56 Contracture of joint (Lower leg)	0.034	0.966	0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.032	0.968	0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.032	0.968	0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.032	0.968	0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.032	0.968	0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.032	0.968	0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.032	0.968	0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.032	0.968	0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.032	0.968	0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.032	0.968	0.000
M24.01 Loose body in joint (Shoulder region)	0.031	0.969	0.000
M24.03 Loose body in joint (Forearm)	0.030	0.969	0.000
M24.09 Loose body in joint (Site unspecified)	0.029	0.970	0.000
M24.08 Loose body in joint (Other)	0.029	0.970	0.000
M24.06 Loose body in joint-Lower leg	0.029	0.970	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.029	0.970	0.000
M24.04 Loose body in joint (Hand)	0.029	0.970	0.000
M24.00 Loose body in joint (Multiple sites)	0.029	0.970	0.000
M24.02 Loose body in joint (Upper arm)	0.026	0.974	0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.023	0.976	0.000
K75.0 Abscess of liver	0.023	0.977	0.000
I78.1 Naevus, nonneoplastic	0.000	0.980	0.020
K70 Alcoholic liver disease	0.020	0.980	0.000
M24.07 Loose body in joint (Ankle and foot)	0.020	0.980	0.000
K74 Fibrosis and cirrhosis of liver	0.019	0.981	0.000
K75 Other inflammatory liver diseases	0.019	0.981	0.000
K70-K77 Diseases of liver	0.019	0.981	0.000
K70.4 Alcoholic hepatic failure	0.018	0.982	0.000
K74.3 Primary biliary cirrhosis	0.018	0.982	0.000
K70.1 Alcoholic hepatitis	0.018	0.982	0.000
K74.5 Biliary cirrhosis, unspecified	0.018	0.982	0.000
K74.6 Other and unspecified cirrhosis of liver	0.017	0.983	0.000
K70.3 Alcoholic cirrhosis of liver	0.017	0.983	0.000
K75.4 Autoimmune hepatitis	0.016	0.984	0.000
K70.0 Alcoholic fatty liver	0.016	0.984	0.000
Y43.3 Other antineoplastic drugs	0.015	0.985	0.000
K70.9 Alcoholic liver disease, unspecified	0.015	0.985	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.014	0.986	0.000
K71 Toxic liver disease	0.014	0.986	0.000
K74.4 Secondary biliary cirrhosis	0.014	0.986	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.014	0.986	0.000
K74.1 Hepatic sclerosis	0.014	0.986	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.014	0.986	0.000
K75.2 Nonspecific reactive hepatitis	0.014	0.986	0.000
K75.1 Phlebitis of portal vein	0.014	0.986	0.000
F45.8 Other somatoform disorders	0.014	0.986	0.000
K77 Liver disorders in diseases classified elsewhere	0.014	0.986	0.000
K73 Chronic hepatitis, not elsewhere classified	0.013	0.986	0.000
K74.0 Hepatic fibrosis	0.012	0.987	0.000
K35.9 Acute appendicitis, unspecified	0.012	0.988	0.000
K72 Hepatic failure, not elsewhere classified	0.012	0.988	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.011	0.989	0.000
K73.9 Chronic hepatitis, unspecified	0.011	0.989	0.000
K75.9 Inflammatory liver disease, unspecified	0.010	0.989	0.000
K71.9 Toxic liver disease, unspecified	0.010	0.989	0.000
K71.8 Toxic liver disease with other disorders of liver	0.010	0.989	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.010	0.989	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.010	0.989	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.010	0.989	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.010	0.989	0.000
K71.2 Toxic liver disease with acute hepatitis	0.010	0.989	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.010	0.989	0.000
K71.0 Toxic liver disease with cholestasis	0.010	0.989	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.010	0.990	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.010	0.990	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.010	0.990	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.010	0.990	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.010	0.990	0.000
K72.9 Hepatic failure, unspecified	0.010	0.990	0.000
K72.1 Chronic hepatic failure	0.009	0.991	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.009	0.991	0.000
F45 Somatoform disorders	0.009	0.991	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.008	0.992	0.000
Y57.9 Drug or medicament, unspecified	0.008	0.992	0.000
K75.8 Other specified inflammatory liver diseases	0.007	0.992	0.000
I78 Diseases of capillaries	0.000	0.993	0.007
F45.4 Persistent somatoform pain disorder	0.007	0.993	0.000
F45.9 Somatoform disorder, unspecified	0.007	0.993	0.000
F45.0 Somatisation disorder	0.007	0.993	0.000
Y57 Other and unspecified drugs and medicaments	0.007	0.993	0.000
F45.2 Hypochondriacal disorder	0.006	0.994	0.000
F45.1 Undifferentiated somatoform disorder	0.006	0.994	0.000
Y43 Primarily systemic agents	0.006	0.994	0.000
I78.8 Other diseases of capillaries	0.000	0.994	0.006
F45.3 Somatoform autonomic dysfunction	0.006	0.994	0.000
O69.1 Labour and delivery complicated by cord around neck, with compression	0.006	0.994	0.000
I78.9 Disease of capillaries, unspecified	0.000	0.994	0.005
Y57.8 Other drugs and medicaments	0.006	0.994	0.000
Y57.5 X-ray contrast media	0.005	0.995	0.000
K72.0 Acute and subacute hepatic failure	0.005	0.995	0.000
Y57.6 Other diagnostic agents	0.005	0.995	0.000
Y57.7 Vitamins, not elsewhere classified	0.005	0.995	0.000
Y57.4 Pharmaceutical excipients	0.005	0.995	0.000
Y57.3 Alcohol deterrents	0.005	0.995	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.005	0.995	0.000
Y57.1 Lipotropic drugs	0.005	0.995	0.000
Y57.0 Appetite depressants [anorectics]	0.005	0.995	0.000
K66.0 Peritoneal adhesions	0.005	0.995	0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess	0.005	0.995	0.000
Y43.9 Primarily systemic agent, unspecified	0.004	0.995	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.004	0.995	0.000
Y43.6 Enzymes, not elsewhere classified	0.004	0.995	0.000
Y43.5 Acidifying and alkalising agents	0.004	0.995	0.000
Y43.2 Antineoplastic natural products	0.004	0.995	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.995	0.004
E13.9 Without complications	0.000	0.996	0.004
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.004	0.996	0.000
F48.0 Neurasthenia	0.004	0.996	0.000
Y43.0 Antiallergic and antiemetic drugs	0.004	0.996	0.000
S02.4 Fracture of malar and maxillary bones	0.004	0.996	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.004	0.996	0.000
Y44 Agents primarily affecting blood constituents	0.004	0.996	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.004	0.996	0.000
Y52 Agents primarily affecting the cardiovascular system	0.004	0.996	0.000
F48 Other neurotic disorders	0.004	0.996	0.000
Y43.4 Immunosuppressive agents	0.004	0.996	0.000
N83.0 Follicular cyst of ovary	0.000	0.996	0.004
F05.9 Delirium, unspecified	0.004	0.996	0.000
Y54.5 Other diuretics	0.004	0.996	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.004	0.996	0.000
M93.9 Osteochondropathy, unspecified	0.004	0.996	0.000
Y44.5 Thrombolytic drugs	0.004	0.996	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.004	0.996	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.004	0.996	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.004	0.996	0.000
Y52.1 Calcium-channel blockers	0.004	0.996	0.000
K35.1 Acute appendicitis with peritoneal abscess	0.004	0.996	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.003	0.996	0.000
M92.6 Juvenile osteochondrosis of tarsus	0.003	0.996	0.000
Y58 Bacterial vaccines	0.003	0.996	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.003	0.996	0.000
T84.1 Mechanical complication of internal fixation device of bones of limb	0.003	0.997	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.003	0.997	0.000
Y54.3 Benzothiadiazine derivatives	0.003	0.997	0.000
O69.9 Labour and delivery complicated by cord complication, unspecified	0.003	0.997	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.003	0.997	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.003	0.997	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.003	0.997	0.000
Y59 Other and unspecified vaccines and biological substances	0.003	0.997	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.003	0.997	0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified	0.003	0.997	0.000
C15.5 Lower third of oesophagus	0.003	0.997	0.000
Y54.4 Loop [high-ceiling] diuretics	0.003	0.997	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.003	0.997	0.000
Y49.2 Other and unspecified antidepressants	0.003	0.997	0.000
M93 Other osteochondropathies	0.003	0.997	0.000
M92 Other juvenile osteochondrosis	0.003	0.997	0.000
O69.2 Labour and delivery complicated by other cord entanglement	0.003	0.997	0.000
Y54.9 Mineral salts, not elsewhere classified	0.003	0.997	0.000
Y54.7 Agents affecting calcification	0.003	0.997	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.003	0.997	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.003	0.997	0.000
Y54.0 Mineralocorticoids	0.003	0.997	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.003	0.997	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.003	0.997	0.000
Y44.7 Plasma substitutes	0.003	0.997	0.000
Y44.6 Natural blood and blood products	0.003	0.997	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.003	0.997	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.003	0.997	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.003	0.997	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.003	0.997	0.000
F44 Dissociative [conversion] disorders	0.003	0.997	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.003	0.997	0.000
Y52.7 Peripheral vasodilators	0.003	0.997	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.003	0.997	0.000
F48.9 Neurotic disorder, unspecified	0.003	0.997	0.000
F48.8 Other specified neurotic disorders	0.003	0.997	0.000
F48.1 Depersonalisation-derealisation syndrome	0.003	0.997	0.000
M50.0 Cervical disk disorder with myelopathy	0.000	0.997	0.003
O69.8 Labour and delivery complicated by other cord complications	0.003	0.997	0.000
Y46.4 Iminostilbenes	0.003	0.997	0.000
M90.78 Fracture of bone in neoplastic disease (Other)	0.003	0.997	0.000
Y54.8 Agents affecting uric acid metabolism	0.003	0.997	0.000
O69.0 Labour and delivery complicated by prolapse of cord	0.003	0.997	0.000
K66 Other disorders of peritoneum	0.003	0.997	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.003	0.997	0.000
O69.5 Labour and delivery complicated by vascular lesion of cord	0.003	0.997	0.000
O69.4 Labour and delivery complicated by vasa praevia	0.003	0.997	0.000
O69.3 Labour and delivery complicated by short cord	0.003	0.997	0.000
E21.0 Primary hyperparathyroidism	0.003	0.997	0.000
K35 Acute appendicitis	0.003	0.997	0.000
Y46.7 Anti-Parkinsonism drugs	0.003	0.997	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.003	0.997	0.000
Y49.9 Psychotropic drug, unspecified	0.003	0.997	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
Y49.7 Psychostimulants with abuse potential	0.003	0.997	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.003	0.997	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.003	0.997	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.003	0.997	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.003	0.997	0.000
S72.10 Pertrochanteric fracture (closed)	0.003	0.997	0.000
K66.1 Haemoperitoneum	0.003	0.997	0.000
Y43.1 Antineoplastic antimetabolites	0.002	0.997	0.001
Y47.1 Benzodiazepines	0.003	0.997	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.003	0.997	0.000
Y58.0 BCG vaccine	0.003	0.997	0.000
R17 Unspecified jaundice	0.003	0.997	0.000
Y49.5 Other antipsychotics and neuroleptics	0.003	0.997	0.000
N32.9 Bladder disorder, unspecified	0.003	0.997	0.000
K76 Other diseases of liver	0.003	0.997	0.000
F44.5 Dissociative convulsions	0.003	0.997	0.000
Y46.6 Other and unspecified antiepileptics	0.003	0.997	0.000
M91-M94 Chondropathies	0.003	0.997	0.000
Y41.5 Antiviral drugs	0.003	0.997	0.000
M90.7 Fracture of bone in neoplastic disease	0.003	0.997	0.000
M92.7 Juvenile osteochondrosis of metatarsus	0.003	0.997	0.000
Y46.8 Antispasticity drugs	0.003	0.997	0.000
Y46.5 Valproic acid	0.003	0.997	0.000
Y46.3 Deoxybarbiturates	0.003	0.997	0.000
Y46.1 Oxazolidinediones	0.003	0.997	0.000
Y46.0 Succinimides	0.003	0.997	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.003	0.997	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.003	0.997	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.003	0.997	0.000
Y47.4 Bromine compounds	0.003	0.997	0.000
Y47.3 Paraldehyde	0.003	0.997	0.000
Y47.2 Chloral derivatives	0.003	0.997	0.000
Y47.0 Barbiturates, not elsewhere classified	0.003	0.997	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.003	0.997	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.003	0.997	0.000
Y58.9 Other and unspecified bacterial vaccines	0.003	0.997	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.003	0.997	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.003	0.997	0.000
Y58.5 Diphtheria vaccine	0.003	0.997	0.000
Y58.4 Tetanus vaccine	0.003	0.997	0.000
Y58.3 Plague vaccine	0.003	0.997	0.000
Y58.2 Cholera vaccine	0.003	0.997	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.003	0.997	0.000
Y53.2 Stimulant laxatives	0.003	0.997	0.000
M90.76 Fracture of bone in neoplastic disease (Lower leg)	0.003	0.997	0.000
F44.0 Dissociative amnesia	0.003	0.997	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.000	0.997	0.003
G81.9 Hemiplegia, unspecified	0.003	0.997	0.000
Y50.9 Central nervous system stimulant, unspecified	0.002	0.997	0.000
Y50.8 Other central nervous system stimulants	0.002	0.997	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.002	0.997	0.000
Y50.1 Opioid receptor antagonists	0.002	0.997	0.000
Y50.0 Analeptics	0.002	0.997	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.002	0.997	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.002	0.997	0.000
Y55.5 Anticommon cold drugs	0.002	0.997	0.000
Y55.4 Expectorants	0.002	0.997	0.000
Y55.3 Antitussives	0.002	0.997	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.002	0.997	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.002	0.997	0.000
Y55.0 Oxytocic drugs	0.002	0.997	0.000
F05 Delirium, not induced by alcohol and other psychoactive substances	0.003	0.997	0.000
N83.3 Acquired atrophy of ovary and Fallopian tube	0.000	0.997	0.003
F43 Reaction to severe stress, and adjustment disorders	0.003	0.997	0.000
K76.7 Hepatorenal syndrome	0.003	0.997	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.003	0.997	0.000
Y41.4 Anthelminthics	0.003	0.997	0.000
Y41.3 Other antiprotozoal drugs	0.003	0.997	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.003	0.997	0.000
Y41.1 Antimycobacterial drugs	0.003	0.997	0.000
M94 Other disorders of cartilage	0.003	0.997	0.000
Y59.9 Vaccine or biological substance, unspecified	0.002	0.997	0.000
Y59.8 Other specified vaccines and biological substances	0.002	0.997	0.000
Y59.2 Protozoal vaccines	0.002	0.997	0.000
Y59.1 Rickettsial vaccines	0.002	0.997	0.000
Y59.0 Viral vaccines	0.002	0.997	0.000
M94.96 Disorder of cartilage, unspecified (Lower leg)	0.003	0.997	0.000
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.003	0.997	0.000
M92.5 Juvenile osteochondrosis of tibia and fibula	0.002	0.997	0.000
M92.1 Juvenile osteochondrosis of radius and ulna	0.002	0.997	0.000
M92.9 Juvenile osteochondrosis, unspecified	0.002	0.997	0.000
M92.8 Other specified juvenile osteochondrosis	0.002	0.997	0.000
M92.4 Juvenile osteochondrosis of patella	0.002	0.997	0.000
M92.3 Other juvenile osteochondrosis of upper limb	0.002	0.997	0.000
M92.2 Juvenile osteochondrosis of hand	0.002	0.997	0.000
M92.0 Juvenile osteochondrosis of humerus	0.002	0.997	0.000
M94.9 Disorder of cartilage, unspecified	0.003	0.997	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.997	0.000
M93.8 Other specified osteochondropathies	0.002	0.997	0.000
M93.2 Osteochondritis dissecans	0.002	0.997	0.000
M93.1 Kienbock's disease of adults	0.002	0.997	0.000
M93.0 Slipped upper femoral epiphysis (nontraumatic)	0.002	0.997	0.000
Y41.0 Sulphonamides	0.002	0.997	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.997	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.997	0.000
Y53.7 Emetics	0.002	0.997	0.000
Y53.6 Antidiarrhoeal drugs	0.002	0.997	0.000
Y53.5 Digestants	0.002	0.997	0.000
Y53.3 Saline and osmotic laxatives	0.002	0.997	0.000
Y53.0 Histamine H2-receptor antagonists	0.002	0.997	0.000
Y56.9 Topical agent, unspecified	0.002	0.997	0.000
Y56.8 Other topical agents	0.002	0.997	0.000
Y56.7 Dental drugs, topically applied	0.002	0.997	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.002	0.997	0.000
Y56.5 Ophthalmological drugs and preparations	0.002	0.997	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.002	0.997	0.000
Y56.3 Emollients, demulcents and protectants	0.002	0.997	0.000
Y56.2 Local astringents and local detergents	0.002	0.997	0.000
Y56.1 Antipruritics	0.002	0.997	0.000
F44.8 Other dissociative [conversion] disorders	0.002	0.997	0.000
F44.7 Mixed dissociative [conversion] disorders	0.002	0.997	0.000
F44.6 Dissociative anaesthesia and sensory loss	0.002	0.997	0.000
F44.3 Trance and possession disorders	0.002	0.997	0.000
F44.2 Dissociative stupor	0.002	0.997	0.000
F44.1 Dissociative fugue	0.002	0.997	0.000
Y59.3 Immunoglobulin	0.002	0.997	0.000
F44.4 Dissociative motor disorders	0.002	0.997	0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.000	0.997	0.003
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.002	0.997	0.000
Z43.1 Attention to gastrostomy	0.003	0.997	0.000
H34.8 Other retinal vascular occlusions	0.000	0.997	0.003
E10.5 With peripheral circulatory complications	0.000	0.997	0.002
N02.9 Unspecified	0.000	0.998	0.002
F40 Phobic anxiety disorders	0.002	0.998	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
F43.0 Acute stress reaction	0.002	0.998	0.000
Y48 Anaesthetics and therapeutic gases	0.002	0.998	0.000
F05.0 Delirium not superimposed on dementia, so described	0.002	0.998	0.000
M90.72 Fracture of bone in neoplastic disease (Upper arm)	0.002	0.998	0.000
Y46.2 Hydantoin derivatives	0.002	0.998	0.000
Y40 Systemic antibiotics	0.002	0.998	0.000
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified	0.000	0.998	0.002
M91 Juvenile osteochondrosis of hip and pelvis	0.002	0.998	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.002	0.998	0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance	0.002	0.998	0.000
E13 Other specified diabetes mellitus	0.000	0.998	0.002
F42 Obsessive-compulsive disorder	0.002	0.998	0.000
K66.9 Disorder of peritoneum, unspecified	0.002	0.998	0.000
K76.5 Hepatic veno-occlusive disease	0.002	0.998	0.000
K76.4 Peliosis hepatis	0.002	0.998	0.000
K76.3 Infarction of liver	0.002	0.998	0.000
K76.2 Central haemorrhagic necrosis of liver	0.002	0.998	0.000
K76.1 Chronic passive congestion of liver	0.002	0.998	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.002	0.998	0.000
F05.1 Delirium superimposed on dementia	0.002	0.998	0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.002	0.998	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.998	0.000
M90.79 Fracture of bone in neoplastic disease (Site unspecified)	0.002	0.998	0.000
M90.77 Fracture of bone in neoplastic disease (Ankle and foot)	0.002	0.998	0.000
M90.74 Fracture of bone in neoplastic disease (Hand)	0.002	0.998	0.000
M90.73 Fracture of bone in neoplastic disease (Forearm)	0.002	0.998	0.000
M90.71 Fracture of bone in neoplastic disease (Shoulder region)	0.002	0.998	0.000
M90.70 Fracture of bone in neoplastic disease (Multiple sites)	0.002	0.998	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.002	0.998	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.002	0.998	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.002	0.998	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.002	0.998	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.002	0.998	0.000
Y51.0 Anticholinesterase agents	0.002	0.998	0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.000	0.998	0.002
J92.9 Pleural plaque without asbestos	0.002	0.998	0.000
Y40.4 Tetracyclines	0.002	0.998	0.000
Z57.2 Occupational exposure to dust	0.000	0.998	0.002
F40.9 Phobic anxiety disorder, unspecified	0.002	0.998	0.000
F43.9 Reaction to severe stress, unspecified	0.002	0.998	0.000
F43.8 Other reactions to severe stress	0.002	0.998	0.000
F44.9 Dissociative [conversion] disorder, unspecified	0.002	0.998	0.000
K66.8 Other specified disorders of peritoneum	0.002	0.998	0.000
Y53.4 Other laxatives	0.002	0.998	0.000
M94.8 Other specified disorders of cartilage	0.002	0.998	0.000
M94.3 Chondrolysis	0.002	0.998	0.000
M94.1 Relapsing polychondritis	0.002	0.998	0.000
M94.0 Chondrocostal junction syndrome [Tietze]	0.002	0.998	0.000
E10.4 With neurological complications	0.000	0.998	0.002
Y44.2 Anticoagulants	0.002	0.998	0.000
H18.1 Bullous keratopathy	0.002	0.998	0.000
M92.10 Juvenile osteochondrosis of radius and ulna, unspecified arm	0.002	0.998	0.000
M92.51 Juvenile osteochondrosis of tibia and fibula, right leg	0.002	0.998	0.000
M92.50 Juvenile osteochondrosis of tibia and fibula, unspecified leg	0.002	0.998	0.000
M93.26 Osteochondritis dissecans knee	0.002	0.998	0.000
M93.86 Other specified osteochondropathies, lower leg	0.002	0.998	0.000
M94.99 Disorder of cartilage, unspecified (Site unspecified)	0.002	0.998	0.000
M94.98 Disorder of cartilage, unspecified (Other)	0.002	0.998	0.000
M94.97 Disorder of cartilage, unspecified (Ankle and foot)	0.002	0.998	0.000
M94.95 Disorder of cartilage, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M94.94 Disorder of cartilage, unspecified (Hand)	0.002	0.998	0.000
M94.93 Disorder of cartilage, unspecified (Forearm)	0.002	0.998	0.000
M94.92 Disorder of cartilage, unspecified (Upper arm)	0.002	0.998	0.000
M94.91 Disorder of cartilage, unspecified (Shoulder region)	0.002	0.998	0.000
M94.90 Disorder of cartilage, unspecified (Multiple sites)	0.002	0.998	0.000
H18.5 Hereditary corneal dystrophies	0.002	0.998	0.000
S52.80 Fracture of other parts of forearm (closed)	0.000	0.998	0.002
D47.1 Chronic myeloproliferative disease	0.000	0.998	0.002
F40.8 Other phobic anxiety disorders	0.002	0.998	0.000
F40.1 Social phobias	0.002	0.998	0.000
F43.1 Posttraumatic stress disorder	0.002	0.998	0.000
M91.1 Juvenile osteochondrosis of head of femur [Legg-Calve-Perthes]	0.002	0.998	0.000
M94.2 Chondromalacia	0.002	0.998	0.000
M94.81 Other specified disorders of cartilage (Shoulder region)	0.002	0.998	0.000
F05.8 Other delirium	0.002	0.998	0.000
Y48.5 Therapeutic gases	0.002	0.998	0.000
Y48.1 Parenteral anaesthetics	0.002	0.998	0.000
Y48.0 Inhaled anaesthetics	0.002	0.998	0.000
F30.0 Hypomania	0.002	0.998	0.000
U80.8 Agent resistant to other penicillin-related antibiotic	0.002	0.998	0.000
Y40.7 Antifungal antibiotics, systemically used	0.002	0.998	0.000
Y40.6 Rifamycins	0.002	0.998	0.000
Y40.2 Chloramphenicol group	0.002	0.998	0.000
Y40.0 Penicillins	0.002	0.998	0.000
G81.1 Spastic hemiplegia	0.002	0.998	0.000
M91.9 Juvenile osteochondrosis of hip and pelvis, unspecified	0.002	0.998	0.000
M91.8 Other juvenile osteochondrosis of hip and pelvis	0.002	0.998	0.000
M91.3 Pseudocoxalgia	0.002	0.998	0.000
M91.2 Coxa plana	0.002	0.998	0.000
M91.0 Juvenile osteochondrosis of pelvis	0.002	0.998	0.000
M94.86 Other specified disorders of cartilage (Lower leg)	0.002	0.998	0.000
E13.8 With unspecified complications	0.000	0.998	0.002
E13.7 With multiple complications	0.000	0.998	0.002
E13.6 With other specified complications	0.000	0.998	0.002
E13.5 With peripheral circulatory complications	0.000	0.998	0.002
E13.4 With neurological complications	0.000	0.998	0.002
E13.3 With ophthalmic complications	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations