TreeWAS – Variant ID: rs12580543

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.271	0.729	0.000
C78.0 Secondary malignant neoplasm of lung	0.268	0.732	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.262	0.738	0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.261	0.739	0.000
C77.3 Axillary and upper limb lymph nodes	0.259	0.741	0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.255	0.745	0.000
C77.9 Lymph node, unspecified	0.246	0.754	0.000
C79 Secondary malignant neoplasm of other sites	0.240	0.760	0.000
C79.9 Secondary malignant neoplasm, unspecified site	0.230	0.770	0.000
C78.4 Secondary malignant neoplasm of small intestine	0.220	0.780	0.000
C77.2 Intra-abdominal lymph nodes	0.216	0.784	0.000
C78.7 Secondary malignant neoplasm of liver	0.214	0.786	0.000
C79.8 Secondary malignant neoplasm of other specified sites	0.212	0.788	0.000
C78.1 Secondary malignant neoplasm of mediastinum	0.211	0.789	0.000
C77.1 Intrathoracic lymph nodes	0.203	0.797	0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.202	0.798	0.000
C79.2 Secondary malignant neoplasm of skin	0.197	0.803	0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.196	0.804	0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.194	0.806	0.000
C77.8 Lymph nodes of multiple regions	0.191	0.809	0.000
C76 Malignant neoplasm of other and ill-defined sites	0.188	0.812	0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.173	0.827	0.000
C78.2 Secondary malignant neoplasm of pleura	0.169	0.831	0.000
C77.4 Inguinal and lower limb lymph nodes	0.162	0.838	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.152	0.848	0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.151	0.849	0.000
C79.6 Secondary malignant neoplasm of ovary	0.148	0.852	0.000
C76.8 Overlapping lesion of other and ill-defined sites	0.135	0.865	0.000
C76.7 Other ill-defined sites	0.135	0.865	0.000
C76.5 Lower limb	0.135	0.865	0.000
C76.4 Upper limb	0.135	0.865	0.000
C76.3 Pelvis	0.135	0.865	0.000
C76.2 Abdomen	0.135	0.865	0.000
C76.1 Thorax	0.135	0.865	0.000
C76.0 Head, face and neck	0.135	0.865	0.000
C80 Malignant neoplasm without specification of site	0.134	0.866	0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.130	0.870	0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.126	0.874	0.000
C77.0 Lymph nodes of head, face and neck	0.112	0.888	0.000
C77.5 Intrapelvic lymph nodes	0.108	0.892	0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.082	0.918	0.000
C80.0 Malignant neoplasm, primary site unknown, so stated	0.078	0.922	0.000
C80.9 Malignant neoplasm, unspecified	0.073	0.927	0.000
D05.1 Intraductal carcinoma in situ	0.000	0.991	0.009
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.000	0.992	0.008
Z50.9 Care involving use of rehabilitation procedure, unspecified	0.000	0.992	0.008
J44 Other chronic obstructive pulmonary disease	0.000	0.992	0.008
Z50 Care involving use of rehabilitation procedures	0.000	0.992	0.008
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.000	0.992	0.008
J44.9 Chronic obstructive pulmonary disease, unspecified	0.000	0.992	0.008
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.000	0.993	0.007
Z50.8 Care involving use of rehabilitation procedures	0.000	0.993	0.007
Z50.4 Psychotherapy, not elsewhere classified	0.000	0.993	0.007
J44.8 Other specified chronic obstructive pulmonary disease	0.000	0.993	0.007
Z50.5 Speech therapy	0.000	0.994	0.006
Z50.1 Other physical therapy	0.000	0.994	0.006
Z50.6 Orthoptic training	0.000	0.994	0.006
Z50.3 Drug rehabilitation	0.000	0.994	0.006
Z50.2 Alcohol rehabilitation	0.000	0.994	0.006
Z50.0 Cardiac rehabilitation	0.000	0.995	0.005
D05 Carcinoma in situ of breast	0.000	0.995	0.005
N20.1 Calculus of ureter	0.000	0.995	0.005
R05 Cough	0.000	0.995	0.005
E87.2 Acidosis	0.000	0.996	0.004
N20.0 Calculus of kidney	0.000	0.996	0.004
N30.9 Cystitis, unspecified	0.000	0.996	0.004
D05.0 Lobular carcinoma in situ	0.000	0.996	0.004
M19.91 Arthrosis, unspecified (Shoulder region)	0.004	0.996	0.000
D05.7 Other carcinoma in situ of breast	0.000	0.996	0.004
F31.9 Bipolar affective disorder, unspecified	0.004	0.996	0.000
N20 Calculus of kidney and ureter	0.000	0.996	0.004
D05.9 Carcinoma in situ of breast, unspecified	0.000	0.996	0.004
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.004	0.996	0.000
F31 Bipolar affective disorder	0.003	0.997	0.000
H16.9 Keratitis, unspecified	0.003	0.997	0.000
I95.9 Hypotension, unspecified	0.000	0.997	0.003
H33.3 Retinal breaks without detachment	0.003	0.997	0.000
H16 Keratitis	0.003	0.997	0.000
H16.0 Corneal ulcer	0.003	0.997	0.000
N30.2 Other chronic cystitis	0.000	0.997	0.003
K91.4 Colostomy and enterostomy malfunction	0.000	0.997	0.003
N30 Cystitis	0.000	0.997	0.003
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.003	0.997	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.003	0.997	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.003	0.997	0.000
L60.8 Other nail disorders	0.003	0.997	0.000
H18 Other disorders of cornea	0.003	0.997	0.000
H18.8 Other specified disorders of cornea	0.003	0.997	0.000
N20.9 Urinary calculus, unspecified	0.000	0.997	0.003
S61.8 Open wound of other parts of wrist and hand	0.003	0.997	0.000
N50.8 Other specified disorders of male genital organs	0.000	0.997	0.003
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.000	0.997	0.003
F31.8 Other bipolar affective disorders	0.003	0.997	0.000
F31.7 Bipolar affective disorder, currently in remission	0.003	0.997	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.003	0.997	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.003	0.997	0.000
H18.6 Keratoconus	0.003	0.997	0.000
N17.9 Acute renal failure, unspecified	0.000	0.997	0.003
F31.0 Bipolar affective disorder, current episode hypomanic	0.003	0.997	0.000
H18.2 Other corneal oedema	0.003	0.997	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.003	0.997	0.000
H33.2 Serous retinal detachment	0.003	0.997	0.000
S64.3 Injury of digital nerve of thumb	0.003	0.997	0.000
E87.7 Fluid overload	0.000	0.997	0.003
N30.8 Other cystitis	0.000	0.997	0.003
H16.8 Other keratitis	0.002	0.997	0.000
H16.4 Corneal neovascularisation	0.002	0.997	0.000
H16.3 Interstitial and deep keratitis	0.002	0.997	0.000
H16.2 Keratoconjunctivitis	0.002	0.997	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.002	0.997	0.000
I78.1 Naevus, nonneoplastic	0.000	0.997	0.003
N20.2 Calculus of kidney with calculus of ureter	0.000	0.997	0.002
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.002	0.997	0.000
H33 Retinal detachments and breaks	0.003	0.997	0.000
G35 Multiple sclerosis	0.003	0.997	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.997	0.003
K83.8 Other specified diseases of biliary tract	0.000	0.998	0.002
N30.4 Irradiation cystitis	0.000	0.998	0.002
H18.9 Disorder of cornea, unspecified	0.002	0.998	0.000
H18.7 Other corneal deformities	0.002	0.998	0.000
H18.3 Changes in corneal membranes	0.002	0.998	0.000
H18.1 Bullous keratopathy	0.002	0.998	0.000
H18.0 Corneal pigmentations and deposits	0.002	0.998	0.000
Z95.2 Presence of prosthetic heart valve	0.000	0.998	0.002
K91.0 Vomiting following gastro-intestinal surgery	0.000	0.998	0.002
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.998	0.002
E87.6 Hypokalaemia	0.000	0.998	0.002
H18.4 Corneal degeneration	0.002	0.998	0.000
N30.1 Interstitial cystitis (chronic)	0.000	0.998	0.002
N30.0 Acute cystitis	0.000	0.998	0.002
H20 Iridocyclitis	0.002	0.998	0.000
H21 Other disorders of iris and ciliary body	0.002	0.998	0.000
H18.5 Hereditary corneal dystrophies	0.002	0.998	0.000
H20.9 Iridocyclitis, unspecified	0.002	0.998	0.000
H54.4 Blindness, one eye	0.002	0.998	0.000
H33.1 Retinoschisis and retinal cysts	0.002	0.998	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.002	0.998	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.002	0.998	0.000
H17 Corneal scars and opacities	0.002	0.998	0.000
H15 Disorders of sclera	0.002	0.998	0.000
H33.0 Retinal detachment with retinal break	0.002	0.998	0.000
N80.1 Endometriosis of ovary	0.002	0.998	0.000
O32.1 Maternal care for breech presentation	0.000	0.998	0.002
H33.4 Traction detachment of retina	0.002	0.998	0.000
N30.3 Trigonitis	0.000	0.998	0.002
Z95.1 Presence of aortocoronary bypass graft	0.000	0.998	0.002
H02.3 Blepharochalasis	0.000	0.998	0.002
K91.9 Postprocedural disorder of digestive system, unspecified	0.000	0.998	0.002
K91.5 Postcholecystectomy syndrome	0.000	0.998	0.002
K91.2 Postsurgical malabsorption, not elsewhere classified	0.000	0.998	0.002
K91.1 Postgastric surgery syndromes	0.000	0.998	0.002
E87.3 Alkalosis	0.000	0.998	0.002
S64 Injury of nerves at wrist and hand level	0.002	0.998	0.000
K61.0 Anal abscess	0.002	0.998	0.000
H21.5 Other adhesions and disruptions of iris and ciliary body	0.002	0.998	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.002	0.998	0.000
E87.4 Mixed disorder of acid-base balance	0.000	0.998	0.002
S64.2 Injury of radial nerve at wrist and hand level	0.002	0.998	0.000
H21.0 Hyphaema	0.002	0.998	0.000
H20.2 Lens-induced iridocyclitis	0.002	0.998	0.000
H20.1 Chronic iridocyclitis	0.002	0.998	0.000
S30.0 Contusion of lower back and pelvis	0.002	0.998	0.000
C61 Malignant neoplasm of prostate	0.002	0.998	0.000
H21.9 Disorder of iris and ciliary body, unspecified	0.002	0.998	0.000
H21.4 Pupillary membranes	0.002	0.998	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.002	0.998	0.000
H21.2 Degeneration of iris and ciliary body	0.002	0.998	0.000
H33.5 Other retinal detachments	0.002	0.998	0.000
H15.9 Disorder of sclera, unspecified	0.002	0.998	0.000
H15.8 Other disorders of sclera	0.002	0.998	0.000
H15.1 Episcleritis	0.002	0.998	0.000
H15.0 Scleritis	0.002	0.998	0.000
H17.9 Corneal scar and opacity, unspecified	0.002	0.998	0.000
H17.8 Other corneal scars and opacities	0.002	0.998	0.000
H17.1 Other central corneal opacity	0.002	0.998	0.000
H17.0 Adherent leukoma	0.002	0.998	0.000
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere	0.002	0.998	0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.002	0.998	0.000
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
H19.1 Herpesviral keratitis and keratoconjunctivitis	0.002	0.998	0.000
H19.0 Scleritis and episcleritis in diseases classified elsewhere	0.002	0.998	0.000
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.002	0.998	0.000
H22.1 Iridocyclitis in other diseases classified elsewhere	0.002	0.998	0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
H20.0 Acute and subacute iridocyclitis	0.002	0.998	0.000
S64.1 Injury of median nerve at wrist and hand level	0.002	0.998	0.000
Z95.3 Presence of xenogenic heart valve	0.000	0.998	0.002
I78 Diseases of capillaries	0.000	0.998	0.002
E87.0 Hyperosmolality and hypernatraemia	0.000	0.998	0.002
H21.8 Other specified disorders of iris and ciliary body	0.002	0.998	0.000
S63.6 Sprain and strain of finger(s)	0.002	0.998	0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.000	0.998	0.002
G93.9 Disorder of brain, unspecified	0.002	0.998	0.000
K55.0 Acute vascular disorders of intestine	0.002	0.998	0.000
K91.3 Postoperative intestinal obstruction	0.000	0.998	0.002
E87.1 Hypo-osmolality and hyponatraemia	0.000	0.998	0.002
T40.2 Other opioids	0.000	0.998	0.002
G37 Other demyelinating diseases of central nervous system	0.002	0.998	0.000
H20.8 Other iridocyclitis	0.001	0.998	0.000
H54.9 Unspecified visual impairment (binocular)	0.002	0.998	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.998	0.002
S64.9 Injury of unspecified nerve at wrist and hand level	0.002	0.998	0.000
S64.8 Injury of other nerves at wrist and hand level	0.002	0.998	0.000
S64.7 Injury of multiple nerves at wrist and hand level	0.002	0.998	0.000
S64.0 Injury of ulnar nerve at wrist and hand level	0.002	0.998	0.000
H54 Blindness and low vision	0.002	0.998	0.000
I77.1 Stricture of artery	0.000	0.998	0.002
Z57.2 Occupational exposure to dust	0.002	0.998	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.002	0.998	0.000
D12.4 Descending colon	0.002	0.998	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.002	0.998	0.000
S30.1 Contusion of abdominal wall	0.002	0.998	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.002	0.998	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.002	0.998	0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.002	0.998	0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.998	0.002
S30 Superficial injury of abdomen, lower back and pelvis	0.002	0.998	0.000
I78.9 Disease of capillaries, unspecified	0.000	0.998	0.001
I78.8 Other diseases of capillaries	0.000	0.998	0.001
H02.4 Ptosis of eyelid	0.000	0.998	0.002
O16 Unspecified maternal hypertension	0.000	0.998	0.002
G37.5 Concentric sclerosis [Balo]	0.001	0.998	0.000
G37.4 Subacute necrotising myelitis	0.001	0.998	0.000
G37.2 Central pontine myelinolysis	0.001	0.998	0.000
G37.1 Central demyelination of corpus callosum	0.001	0.998	0.000
G37.0 Diffuse sclerosis	0.001	0.998	0.000
H54.0 Blindness, both eyes	0.001	0.998	0.000
K51.2 Ulcerative (chronic) proctitis	0.000	0.998	0.002
K74.3 Primary biliary cirrhosis	0.001	0.998	0.000
L60.3 Nail dystrophy	0.001	0.998	0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.001	0.998	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.998	0.001
H02.5 Other disorders affecting eyelid function	0.000	0.999	0.001
H54.6 Unqualified visual loss, one eye	0.001	0.999	0.000
H54.5 Low vision, one eye	0.001	0.999	0.000
H54.3 Unqualified visual loss, both eyes	0.001	0.999	0.000
H54.2 Low vision, both eyes	0.001	0.999	0.000
H54.1 Blindness, one eye, low vision, other eye	0.001	0.999	0.000
S65.0 Injury of ulnar artery at wrist and hand level	0.001	0.999	0.000
G96.0 Cerebrospinal fluid leak	0.001	0.999	0.000
G36 Other acute disseminated demyelination	0.001	0.999	0.000
I25.5 Ischaemic cardiomyopathy	0.001	0.999	0.000
K55.2 Angiodysplasia of colon	0.001	0.999	0.000
L60 Nail disorders	0.001	0.999	0.000
N50.0 Atrophy of testis	0.000	0.999	0.001
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.001	0.999	0.000
S30.2 Contusion of external genital organs	0.001	0.999	0.000
N50 Other disorders of male genital organs	0.000	0.999	0.001
F34.1 Dysthymia	0.001	0.999	0.000
F60.9 Personality disorder, unspecified	0.000	0.999	0.001
S64.4 Injury of digital nerve of other finger	0.001	0.999	0.000
S62.40 Multiple fractures of metacarpal bones (closed)	0.001	0.999	0.000
G96.1 Disorders of meninges, not elsewhere classified	0.001	0.999	0.000
S65 Injury of blood vessels at wrist and hand level	0.001	0.999	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.001	0.999	0.000
D86.1 Sarcoidosis of lymph nodes	0.001	0.999	0.000
K55.9 Vascular disorder of intestine, unspecified	0.001	0.999	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.000	0.999	0.001
S65.1 Injury of radial artery at wrist and hand level	0.001	0.999	0.000
K83 Other diseases of biliary tract	0.000	0.999	0.001
G36.9 Acute disseminated demyelination, unspecified	0.001	0.999	0.000
G36.8 Other specified acute disseminated demyelination	0.001	0.999	0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.001	0.999	0.000
G36.0 Neuromyelitis optica [Devic]	0.001	0.999	0.000
H54.7 Unspecified visual loss	0.001	0.999	0.000
S63.0 Dislocation of wrist	0.001	0.999	0.000
G96 Other disorders of central nervous system	0.001	0.999	0.000
K55 Vascular disorders of intestine	0.001	0.999	0.000
D25.9 Leiomyoma of uterus, unspecified	0.000	0.999	0.001
I71.0 Dissection of aorta [any part]	0.000	0.999	0.001
K22.4 Dyskinesia of oesophagus	0.001	0.999	0.000
L60.5 Yellow nail syndrome	0.001	0.999	0.000
L60.4 Beau's lines	0.001	0.999	0.000
L60.2 Onychogryphosis	0.001	0.999	0.000
L60.1 Onycholysis	0.001	0.999	0.000
N49.2 Inflammatory disorders of scrotum	0.001	0.999	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.999	0.001
N50.9 Disorder of male genital organs, unspecified	0.000	0.999	0.001
Q38.7 Pharyngeal pouch	0.001	0.999	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.000	0.999	0.001
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.000	0.999	0.001
S62.4 Multiple fractures of metacarpal bones	0.001	0.999	0.000
S63.1 Dislocation finger	0.001	0.999	0.000
S63.7 Sprain and strain of other and unspecified parts of hand	0.001	0.999	0.000
S63.5 Sprain and strain of wrist	0.001	0.999	0.000
S63.3 Traumatic rupture of ligament of wrist and carpus	0.001	0.999	0.000
S63.2 Multiple dislocations of fingers	0.001	0.999	0.000
S65.9 Injury of unspecified blood vessel at wrist and hand level	0.001	0.999	0.000
S65.8 Injury of other blood vessels at wrist and hand level	0.001	0.999	0.000
S65.7 Injury of multiple blood vessels at wrist and hand level	0.001	0.999	0.000
S65.5 Injury of blood vessel(s) of other finger	0.001	0.999	0.000
S65.4 Injury of blood vessel(s) of thumb	0.001	0.999	0.000
S65.3 Injury of deep palmar arch	0.001	0.999	0.000
S65.2 Injury of superficial palmar arch	0.001	0.999	0.000
K55.8 Other vascular disorders of intestine	0.001	0.999	0.000
K74.0 Hepatic fibrosis	0.001	0.999	0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.000	0.999	0.001
M24.23 Disorder of ligament (Forearm)	0.001	0.999	0.000
M99.53 Intervertebral disc stenosis of neural canal (Lumbar region)	0.001	0.999	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.001	0.999	0.000
I71 Aortic aneurysm and dissection	0.000	0.999	0.001
S62.50 Fracture of thumb (closed)	0.001	0.999	0.000
S72.00 Fracture of neck of femur (closed)	0.000	0.999	0.001
S82.20 Fracture of shaft of tibia (closed)	0.001	0.999	0.000
G90.2 Horner's syndrome	0.001	0.999	0.000
G96.9 Disorder of central nervous system, unspecified	0.001	0.999	0.000
G96.8 Other specified disorders of central nervous system	0.001	0.999	0.000
K55.1 Chronic vascular disorders of intestine	0.001	0.999	0.000
K83.9 Disease of biliary tract, unspecified	0.000	0.999	0.001
K83.5 Biliary cyst	0.000	0.999	0.001
K83.4 Spasm of sphincter of Oddi	0.000	0.999	0.001
K83.3 Fistula of bile duct	0.000	0.999	0.001
K83.2 Perforation of bile duct	0.000	0.999	0.001
L60.9 Nail disorder, unspecified	0.001	0.999	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.000	0.999	0.001
M24.26 Disorder of ligament (Lower leg)	0.001	0.999	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.001	0.999	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.999	0.001
L29.0 Pruritus ani	0.001	0.999	0.000
S62.5 Fracture of thumb	0.001	0.999	0.000
S62.41 Multiple fractures of metacarpal bones (open)	0.001	0.999	0.000
S63.11 Subluxation and dislocation of metacarpophalangeal joint of thumb	0.001	0.999	0.000
K61.3 Ischiorectal abscess	0.001	0.999	0.000
O32.9 Maternal care for malpresentation of foetus, unspecified	0.000	0.999	0.001
O32.6 Maternal care for compound presentation	0.000	0.999	0.001
O32.3 Maternal care for face, brow and chin presentation	0.000	0.999	0.001
O32.2 Maternal care for transverse and oblique lie	0.000	0.999	0.001
O47.0 False labour before 37 completed weeks of gestation	0.000	0.999	0.001
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.001	0.999	0.000
T81.3 Disruption of operation wound, not elsewhere classified	0.001	0.999	0.000
V18.0 Driver injured in nontraffic accident	0.000	0.999	0.001
S69 Other and unspecified injuries of wrist and hand	0.001	0.999	0.000
S60-S69 Injuries to the wrist and hand	0.001	0.999	0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.000	0.999	0.001
D86.9 Sarcoidosis, unspecified	0.001	0.999	0.000
D86.8 Sarcoidosis of other and combined sites	0.001	0.999	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.999	0.001
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.999	0.001
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.999	0.001
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.999	0.001
K74.6 Other and unspecified cirrhosis of liver	0.001	0.999	0.000
K83.1 Obstruction of bile duct	0.000	0.999	0.001
O32.8 Maternal care for other malpresentation of foetus	0.000	0.999	0.001
S69.9 Unspecified injury of wrist and hand	0.001	0.999	0.000
S62 Fracture at wrist and hand level	0.001	0.999	0.000
S72.10 Pertrochanteric fracture (closed)	0.000	0.999	0.001
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.999	0.001
L53.9 Erythematous condition, unspecified	0.001	0.999	0.000
G91.8 Other hydrocephalus	0.001	0.999	0.000
O32.4 Maternal care for high head at term	0.000	0.999	0.001
S62.6 Fracture of other finger	0.001	0.999	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.000	0.999	0.001
T42.4 Benzodiazepines	0.000	0.999	0.001
S68 Traumatic amputation of wrist and hand	0.001	0.999	0.000
S62.51 Fracture of thumb (open)	0.001	0.999	0.000
S72.20 Subtrochanteric fracture (closed)	0.000	0.999	0.001
G47.1 Disorders of excessive somnolence [hypersomnias]	0.001	0.999	0.000
G90.0 Idiopathic peripheral autonomic neuropathy	0.001	0.999	0.000
I72.3 Aneurysm of iliac artery	0.000	0.999	0.001
K29.5 Chronic gastritis, unspecified	0.000	0.999	0.001
S62.7 Multiple fractures of fingers	0.001	0.999	0.000
S62.1 Fracture of other carpal bone(s)	0.001	0.999	0.000
S68.0 Traumatic amputation of thumb (complete)(partial)	0.001	0.999	0.000
S69.8 Other specified injuries of wrist and hand	0.001	0.999	0.000
S69.7 Multiple injuries of wrist and hand	0.001	0.999	0.000
Z95.4 Presence of other heart-valve replacement	0.000	0.999	0.001
D86 Sarcoidosis	0.001	0.999	0.000
F34 Persistent mood [affective] disorders	0.001	0.999	0.000
N17 Acute renal failure	0.000	0.999	0.001
D04.6 Skin of upper limb, including shoulder	0.000	0.999	0.001
G91.1 Obstructive hydrocephalus	0.001	0.999	0.000
O12.0 Gestational oedema	0.000	0.999	0.001
K61 Abscess of anal and rectal regions	0.001	0.999	0.000
K74 Fibrosis and cirrhosis of liver	0.001	0.999	0.000
M47.86 Other spondylosis (Lumbar region)	0.000	0.999	0.001
D68.8 Other specified coagulation defects	0.000	0.999	0.001
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.000	0.999	0.001
N08.3 Glomerular disorders in diabetes mellitus	0.000	0.999	0.001
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.001	0.999	0.000
S68.8 Traumatic amputation of other parts of wrist and hand	0.001	0.999	0.000
S68.4 Traumatic amputation of hand at wrist level	0.001	0.999	0.000
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.001	0.999	0.000
S90.8 Other superficial injuries of ankle and foot	0.001	0.999	0.000
Z57.8 Occupational exposure to other risk-factors	0.001	0.999	0.000
G90 Disorders of autonomic nervous system	0.001	0.999	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.000	0.999	0.001
S62.11 Fracture of other carpal bone(s) (open)	0.001	0.999	0.000
S62.10 Fracture of other carpal bone(s) (closed)	0.001	0.999	0.000
S62.61 Fracture of other finger (open)	0.001	0.999	0.000
S62.60 Fracture of other finger (closed)	0.001	0.999	0.000
S62.71 Multiple fractures of fingers (open)	0.001	0.999	0.000
S62.70 Multiple fractures of fingers (closed)	0.001	0.999	0.000
C69.3 Choroid	0.001	0.999	0.000
D86.3 Sarcoidosis of skin	0.001	0.999	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.001	0.999	0.000
F34.9 Persistent mood [affective] disorder, unspecified	0.001	0.999	0.000
F34.8 Other persistent mood [affective] disorders	0.001	0.999	0.000
F34.0 Cyclothymia	0.001	0.999	0.000
K82.8 Other specified diseases of gallbladder	0.000	0.999	0.001
L29.2 Pruritus vulvae	0.001	0.999	0.000
N17.8 Other acute renal failure	0.000	0.999	0.001
N17.2 Acute renal failure with medullary necrosis	0.000	0.999	0.001
N17.1 Acute renal failure with acute cortical necrosis	0.000	0.999	0.001
N50.1 Vascular disorders of male genital organs	0.000	0.999	0.001
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.001	0.999	0.000
G90.8 Other disorders of autonomic nervous system	0.001	0.999	0.000
G90.4 Autonomic dysreflexia	0.001	0.999	0.000
G90.3 Multisystem degeneration	0.001	0.999	0.000
G90.1 Familial dysautonomia [Riley-Day]	0.001	0.999	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.999	0.001
K61.4 Intrasphincteric abscess	0.001	0.999	0.000
K61.2 Anorectal abscess	0.001	0.999	0.000
K61.1 Rectal abscess	0.001	0.999	0.000
K74.5 Biliary cirrhosis, unspecified	0.001	0.999	0.000
K74.4 Secondary biliary cirrhosis	0.001	0.999	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.001	0.999	0.000
K74.1 Hepatic sclerosis	0.001	0.999	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.001	0.999	0.000
X62.9 Unspecified place	0.000	0.999	0.001
O15 Eclampsia	0.000	0.999	0.001
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.000	0.999	0.001
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.999	0.001
G95.2 Cord compression, unspecified	0.001	0.999	0.000
K86.3 Pseudocyst of pancreas	0.000	0.999	0.001
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.001	0.999	0.000
S62.2 Fracture of first metacarpal bone	0.001	0.999	0.000
S72.0 Fracture of neck of femur	0.000	0.999	0.001
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.000	0.999	0.001
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.999	0.001
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.001	0.999	0.000
S62.21 Fracture of first metacarpal bone (open)	0.001	0.999	0.000
S72.01 Fracture of neck of femur (open)	0.000	0.999	0.001
D41.0 Kidney	0.000	0.999	0.001
D86.0 Sarcoidosis of lung	0.001	0.999	0.000
G93.2 Benign intracranial hypertension	0.001	0.999	0.000
M93.9 Osteochondropathy, unspecified	0.001	0.999	0.000
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.999	0.001
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.999	0.001
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.000	0.999	0.001
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.000	0.999	0.001
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.000	0.999	0.001
O15.9 Eclampsia, unspecified as to time period	0.000	0.999	0.001
O15.2 Eclampsia in the puerperium	0.000	0.999	0.001
O15.1 Eclampsia in labour	0.000	0.999	0.001
O15.0 Eclampsia in pregnancy	0.000	0.999	0.001
S62.8 Fracture of other and unspecified parts of wrist and hand	0.001	0.999	0.000
S62.3 Fracture of other metacarpal bone	0.001	0.999	0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.001	0.999	0.000
G91 Hydrocephalus	0.001	0.999	0.000
H02 Other disorders of eyelid	0.000	0.999	0.001
I77 Other disorders of arteries and arterioles	0.000	0.999	0.001
D00-D09 In situ neoplasms	0.000	0.999	0.001
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.001	0.999	0.000
S62.31 Fracture of other metacarpal bone (open)	0.001	0.999	0.000
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.001	0.999	0.000
S72.11 Pertrochanteric fracture (open)	0.000	0.999	0.001
C71.3 Parietal lobe	0.001	0.999	0.000
G91.3 Posttraumatic hydrocephalus, unspecified	0.001	0.999	0.000
G91.2 Normal-pressure hydrocephalus	0.001	0.999	0.000
G91.0 Communicating hydrocephalus	0.001	0.999	0.000
G97.1 Other reaction to spinal and lumbar puncture	0.001	0.999	0.000
H02.7 Other degenerative disorders of eyelid and periocular area	0.000	0.999	0.001
H02.2 Lagophthalmos	0.000	0.999	0.001
I77.5 Necrosis of artery	0.000	0.999	0.001
I77.4 Coeliac artery compression syndrome	0.000	0.999	0.001
I77.3 Arterial fibromuscular dysplasia	0.000	0.999	0.001
I77.2 Rupture of artery	0.000	0.999	0.001
I77.0 Arteriovenous fistula, acquired	0.000	0.999	0.001
K83.0 Cholangitis	0.000	0.999	0.001
O12.2 Gestational oedema with proteinuria	0.000	0.999	0.001
O14.9 Preeclampsia, unspecified	0.000	0.999	0.001
O14.2 HELLP syndrome	0.000	0.999	0.001
O32.0 Maternal care for unstable lie	0.000	0.999	0.001
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.000	0.999	0.001
S62.0 Fracture of navicular [scaphoid] bone of hand	0.001	0.999	0.000
S72.1 Pertrochanteric fracture	0.000	0.999	0.001
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.001	0.999	0.000
W19.2 School, other institution and public administrative area	0.000	0.999	0.001
D02 Carcinoma in situ of middle ear and respiratory system	0.000	0.999	0.001
D01 Carcinoma in situ of other and unspecified digestive organs	0.000	0.999	0.001
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.000	0.999	0.001
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.000	0.999	0.001
Q38 Other congenital malformations of tongue, mouth and pharynx	0.001	0.999	0.000
S67 Crushing injury of wrist and hand	0.001	0.999	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.000	0.999	0.001
S62.01 Fracture of navicular [scaphoid] bone of hand (open)	0.001	0.999	0.000
S72.21 Subtrochanteric fracture (open)	0.000	0.999	0.001
D00.2 Stomach	0.000	0.999	0.001
D00.1 Oesophagus	0.000	0.999	0.001
D00.0 Lip, oral cavity and pharynx	0.000	0.999	0.001
D01.9 Digestive organ, unspecified	0.000	0.999	0.001
D01.7 Other specified digestive organs	0.000	0.999	0.001
D01.5 Liver, gallbladder and bile ducts	0.000	0.999	0.001
D01.4 Other and unspecified parts of intestine	0.000	0.999	0.001
D01.3 Anus and anal canal	0.000	0.999	0.001
D01.2 Rectum	0.000	0.999	0.001
D01.1 Rectosigmoid junction	0.000	0.999	0.001
D01.0 Colon	0.000	0.999	0.001
D02.4 Respiratory system, unspecified	0.000	0.999	0.001
D02.3 Other parts of respiratory system	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations