TreeWAS – Variant ID: rs12589060

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.055	0.945	0.000
Q66 Congenital deformities of feet	0.050	0.950	0.000
Q54 Hypospadias	0.049	0.951	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.049	0.951	0.000
Q66.8 Other congenital deformities of feet	0.048	0.952	0.000
Q54.0 Hypospadias, balanic	0.048	0.952	0.000
Q50-Q56 Congenital malformations of genital organs	0.047	0.953	0.000
J33.8 Other polyp of sinus	0.000	0.954	0.046
Q54.9 Hypospadias, unspecified	0.045	0.955	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.045	0.955	0.000
Q66.3 Other congenital varus deformities of feet	0.043	0.957	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.043	0.957	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.043	0.957	0.000
Q74 Other congenital malformations of limb(s)	0.042	0.958	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.041	0.959	0.000
Q80-Q89 Other congenital malformations	0.041	0.959	0.000
Q66.2 Metatarsus varus	0.041	0.959	0.000
Q54.1 Hypospadias, penile	0.040	0.960	0.000
Q87.4 Marfan's syndrome	0.040	0.960	0.000
Q25 Congenital malformations of great arteries	0.040	0.960	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.039	0.961	0.000
Q66.0 Talipes equinovarus	0.039	0.961	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.038	0.962	0.000
T45.5 Anticoagulants	0.038	0.962	0.000
Q65 Congenital deformities of hip	0.037	0.963	0.000
Q66.9 Congenital deformity of feet, unspecified	0.037	0.963	0.000
Q51 Congenital malformations of uterus and cervix	0.037	0.963	0.000
Q66.6 Other congenital valgus deformities of feet	0.036	0.963	0.000
Q28 Other congenital malformations of circulatory system	0.036	0.964	0.000
Q66.5 Congenital pes planus	0.036	0.964	0.000
Q66.4 Talipes calcaneovalgus	0.036	0.964	0.000
Q66.1 Talipes calcaneovarus	0.036	0.964	0.000
Q54.4 Congenital chordee	0.035	0.964	0.000
Q54.3 Hypospadias, perineal	0.035	0.964	0.000
Q54.2 Hypospadias, penoscrotal	0.035	0.964	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.035	0.965	0.000
Q68 Other congenital musculoskeletal deformities	0.035	0.965	0.000
Q35-Q37 Cleft lip and cleft palate	0.035	0.965	0.000
Q70 Syndactyly	0.035	0.965	0.000
Q75 Other congenital malformations of skull and face bones	0.035	0.965	0.000
Q73 Reduction defects of unspecified limb	0.035	0.965	0.000
Q72 Reduction defects of lower limb	0.035	0.965	0.000
Q71 Reduction defects of upper limb	0.035	0.965	0.000
Q69 Polydactyly	0.035	0.965	0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.035	0.965	0.000
Q23 Congenital malformations of aortic and mitral valves	0.035	0.965	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.035	0.965	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.035	0.965	0.000
Q25.6 Stenosis of pulmonary artery	0.035	0.965	0.000
Q66.7 Pes cavus	0.035	0.965	0.000
Q79.6 Ehlers-Danlos syndrome	0.035	0.965	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.035	0.965	0.000
Q89 Other congenital malformations, not elsewhere classified	0.035	0.965	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.035	0.965	0.000
Q27 Other congenital malformations of peripheral vascular system	0.034	0.966	0.000
Q55 Other congenital malformations of male genital organs	0.034	0.966	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.034	0.966	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.034	0.966	0.000
Q25.1 Coarctation of aorta	0.034	0.966	0.000
Q54.8 Other hypospadias	0.034	0.966	0.000
Q76 Congenital malformations of spine and bony thorax	0.034	0.966	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.034	0.966	0.000
Q79.0 Congenital diaphragmatic hernia	0.033	0.967	0.000
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.033	0.967	0.000
Q51.3 Bicornate uterus	0.033	0.967	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.033	0.967	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.033	0.967	0.000
T45.0 Antiallergic and antiemetic drugs	0.033	0.967	0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.032	0.968	0.000
Q74.1 Congenital malformation of knee	0.032	0.968	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.032	0.968	0.000
Q26 Congenital malformations of great veins	0.032	0.968	0.000
Q53 Undescended testicle	0.032	0.968	0.000
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.031	0.969	0.000
Q25.0 Patent ductus arteriosus	0.031	0.969	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.031	0.969	0.000
Q79.5 Other congenital malformations of abdominal wall	0.031	0.969	0.000
Q79.4 Prune belly syndrome	0.031	0.969	0.000
Q79.3 Gastroschisis	0.031	0.969	0.000
Q79.2 Exomphalos	0.031	0.969	0.000
Q79.1 Other congenital malformations of diaphragm	0.031	0.969	0.000
T45.2 Vitamins, not elsewhere classified	0.031	0.969	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.031	0.969	0.000
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.030	0.969	0.000
Q74.9 Unspecified congenital malformation of limb(s)	0.030	0.969	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.030	0.969	0.000
Q74.3 Arthrogryposis multiplex congenita	0.030	0.969	0.000
Q52 Other congenital malformations of female genitalia	0.030	0.970	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.030	0.970	0.000
Q78 Other osteochondrodysplasias	0.030	0.970	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.030	0.970	0.000
T39.0 Salicylates	0.030	0.970	0.000
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.030	0.970	0.000
Q87.3 Congenital malformation syndromes involving early overgrowth	0.030	0.970	0.000
Q23.0 Congenital stenosis of aortic valve	0.030	0.970	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.029	0.970	0.000
Q84 Other congenital malformations of integument	0.029	0.970	0.000
Q81 Epidermolysis bullosa	0.029	0.970	0.000
Q80 Congenital ichthyosis	0.029	0.970	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.029	0.971	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.029	0.971	0.000
Q89.2 Congenital malformations of other endocrine glands	0.029	0.971	0.000
Q25.3 Stenosis of aorta	0.029	0.971	0.000
T45.4 Iron and its compounds	0.029	0.971	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.029	0.971	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.029	0.971	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.029	0.971	0.000
T42.1 Iminostilbenes	0.029	0.971	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.029	0.971	0.000
Q25.8 Other congenital malformations of great arteries	0.029	0.971	0.000
Q25.5 Atresia of pulmonary artery	0.029	0.971	0.000
Q25.2 Atresia of aorta	0.029	0.971	0.000
Q22.1 Congenital pulmonary valve stenosis	0.029	0.971	0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.029	0.971	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.028	0.971	0.000
T39.4 Antirheumatics, not elsewhere classified	0.028	0.972	0.000
T39.2 Pyrazolone derivatives	0.028	0.972	0.000
Q83 Congenital malformations of breast	0.028	0.972	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.028	0.972	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.028	0.972	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.028	0.972	0.000
Q23.3 Congenital mitral insufficiency	0.028	0.972	0.000
Q35 Cleft palate	0.028	0.972	0.000
Q65.9 Congenital deformity of hip, unspecified	0.027	0.972	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.027	0.973	0.000
T45.8 Other primarily systemic and haematological agents	0.027	0.973	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.027	0.973	0.000
T45.6 Fibrinolysis-affecting drugs	0.027	0.973	0.000
T45.3 Enzymes, not elsewhere classified	0.027	0.973	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.027	0.973	0.000
Q27.1 Congenital renal artery stenosis	0.027	0.973	0.000
Q25.4 Other congenital malformations of aorta	0.027	0.973	0.000
Q65.6 Unstable hip	0.027	0.973	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.027	0.973	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.027	0.973	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.027	0.973	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.027	0.973	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.027	0.973	0.000
Q67.6 Pectus excavatum	0.027	0.973	0.000
Q51.4 Unicornate uterus	0.027	0.973	0.000
Q89.3 Situs inversus	0.027	0.973	0.000
Q65.8 Other congenital deformities of hip	0.027	0.973	0.000
Q27.3 Peripheral arteriovenous malformation	0.027	0.973	0.000
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.026	0.973	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.026	0.973	0.000
Q51.6 Embryonic cyst of cervix	0.026	0.973	0.000
Q51.5 Agenesis and aplasia of cervix	0.026	0.973	0.000
Q51.0 Agenesis and aplasia of uterus	0.026	0.973	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.026	0.974	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.026	0.974	0.000
Q28.1 Other malformations of precerebral vessels	0.026	0.974	0.000
T42.3 Barbiturates	0.026	0.974	0.000
Q37 Cleft palate with cleft lip	0.026	0.974	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.026	0.974	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.026	0.974	0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.026	0.974	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.026	0.974	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.025	0.974	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.025	0.974	0.000
Q68.4 Congenital bowing of tibia and fibula	0.025	0.974	0.000
Q68.3 Congenital bowing of femur	0.025	0.974	0.000
Q68.2 Congenital deformity of knee	0.025	0.974	0.000
Q68.1 Congenital deformity of hand	0.025	0.974	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.025	0.974	0.000
Q70.3 Webbed toes	0.025	0.974	0.000
Q36 Cleft lip	0.025	0.974	0.000
Q70.9 Syndactyly, unspecified	0.025	0.974	0.000
Q70.4 Polysyndactyly	0.025	0.974	0.000
Q70.2 Fused toes	0.025	0.974	0.000
Q70.1 Webbed fingers	0.025	0.974	0.000
Q70.0 Fused fingers	0.025	0.974	0.000
Q69.9 Polydactyly, unspecified	0.025	0.974	0.000
Q69.2 Accessory toe(s)	0.025	0.974	0.000
Q69.1 Accessory thumb(s)	0.025	0.974	0.000
Q69.0 Accessory finger(s)	0.025	0.974	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.025	0.974	0.000
Q71.8 Other reduction defects of upper limb(s)	0.025	0.974	0.000
Q71.6 Lobster-claw hand	0.025	0.974	0.000
Q71.5 Longitudinal reduction defect of ulna	0.025	0.974	0.000
Q71.4 Longitudinal reduction defect of radius	0.025	0.974	0.000
Q71.3 Congenital absence of hand and finger(s)	0.025	0.974	0.000
Q71.2 Congenital absence of both forearm and hand	0.025	0.974	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.025	0.974	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.025	0.974	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.025	0.974	0.000
Q72.8 Other reduction defects of lower limb(s)	0.025	0.974	0.000
Q72.7 Split foot	0.025	0.974	0.000
Q72.6 Longitudinal reduction defect of fibula	0.025	0.974	0.000
Q72.5 Longitudinal reduction defect of tibia	0.025	0.974	0.000
Q72.4 Longitudinal reduction defect of femur	0.025	0.974	0.000
Q72.3 Congenital absence of foot and toe(s)	0.025	0.974	0.000
Q72.2 Congenital absence of both lower leg and foot	0.025	0.974	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.025	0.974	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.025	0.974	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.025	0.974	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.025	0.974	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.025	0.974	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.025	0.974	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.025	0.974	0.000
Q75.5 Oculomandibular dysostosis	0.025	0.974	0.000
Q75.4 Mandibulofacial dysostosis	0.025	0.974	0.000
Q75.3 Macrocephaly	0.025	0.974	0.000
Q75.2 Hypertelorism	0.025	0.974	0.000
Q75.1 Craniofacial dysostosis	0.025	0.974	0.000
Q75.0 Craniosynostosis	0.025	0.974	0.000
Q55.6 Other congenital malformations of penis	0.025	0.975	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.025	0.975	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.025	0.975	0.000
Q23.4 Hypoplastic left heart syndrome	0.025	0.975	0.000
Q23.2 Congenital mitral stenosis	0.025	0.975	0.000
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.025	0.975	0.000
Q50.3 Other congenital malformations of ovary	0.025	0.975	0.000
Q50.2 Congenital torsion of ovary	0.025	0.975	0.000
Q50.1 Developmental ovarian cyst	0.025	0.975	0.000
Q50.0 Congenital absence of ovary	0.025	0.975	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.025	0.975	0.000
Q22.5 Ebstein's anomaly	0.025	0.975	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.025	0.975	0.000
Q53.9 Undescended testicle, unspecified	0.025	0.975	0.000
Q89.9 Congenital malformation, unspecified	0.025	0.975	0.000
Q89.8 Other specified congenital malformations	0.025	0.975	0.000
Q89.7 Multiple congenital malformations, not elsewhere classified	0.025	0.975	0.000
Q89.4 Conjoined twins	0.025	0.975	0.000
Q89.1 Congenital malformations of adrenal gland	0.025	0.975	0.000
Q89.0 Congenital malformations of spleen	0.025	0.975	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.025	0.975	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.025	0.975	0.000
Q22.6 Hypoplastic right heart syndrome	0.025	0.975	0.000
Q22.4 Congenital tricuspid stenosis	0.025	0.975	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.025	0.975	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.025	0.975	0.000
Q22.0 Pulmonary valve atresia	0.025	0.975	0.000
Q55.0 Absence and aplasia of testis	0.025	0.975	0.000
Q27.4 Congenital phlebectasia	0.025	0.975	0.000
Q27.2 Other congenital malformations of renal artery	0.025	0.975	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.025	0.975	0.000
Q12 Congenital lens malformations	0.025	0.975	0.000
Q55.9 Congenital malformation of male genital organ, unspecified	0.025	0.975	0.000
Q55.8 Other specified congenital malformations of male genital organs	0.025	0.975	0.000
Q55.5 Congenital absence and aplasia of penis	0.025	0.975	0.000
Q55.3 Atresia of vas deferens	0.025	0.975	0.000
Q55.1 Hypoplasia of testis and scrotum	0.025	0.975	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.025	0.975	0.000
T42.2 Succinimides and oxazolidinediones	0.025	0.975	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.024	0.975	0.000
Q76.8 Other congenital malformations of bony thorax	0.024	0.975	0.000
Q76.7 Congenital malformation of sternum	0.024	0.975	0.000
Q76.6 Other congenital malformations of ribs	0.024	0.975	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.024	0.975	0.000
Q76.2 Congenital spondylolisthesis	0.024	0.975	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.024	0.975	0.000
Q56.4 Indeterminate sex, unspecified	0.024	0.976	0.000
Q56.3 Pseudohermaphroditism, unspecified	0.024	0.976	0.000
Q56.2 Female pseudohermaphroditism, not elsewhere classified	0.024	0.976	0.000
Q56.1 Male pseudohermaphroditism, not elsewhere classified	0.024	0.976	0.000
Q56.0 Hermaphroditism, not elsewhere classified	0.024	0.976	0.000
T38.1 Thyroid hormones and substitutes	0.024	0.976	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.024	0.976	0.000
T36 Poisoning by systemic antibiotics	0.024	0.976	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.024	0.976	0.000
Q51.2 Other doubling of uterus	0.024	0.976	0.000
Q67.8 Other congenital deformities of chest	0.024	0.976	0.000
Q67.7 Pectus carinatum	0.024	0.976	0.000
Q67.3 Plagiocephaly	0.024	0.976	0.000
Q67.2 Dolichocephaly	0.024	0.976	0.000
Q67.1 Compression facies	0.024	0.976	0.000
Q67.0 Facial asymmetry	0.024	0.976	0.000
O42.9 Premature rupture of membranes, unspecified	0.023	0.977	0.000
Q78.2 Osteopetrosis	0.023	0.977	0.000
T47.2 Stimulant laxatives	0.023	0.977	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.023	0.977	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.023	0.977	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.023	0.977	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.023	0.977	0.000
Q77.6 Chondroectodermal dysplasia	0.023	0.977	0.000
Q77.5 Diastrophic dysplasia	0.023	0.977	0.000
Q77.3 Chondrodysplasia punctata	0.023	0.977	0.000
Q77.2 Short rib syndrome	0.023	0.977	0.000
Q77.1 Thanatophoric short stature	0.023	0.977	0.000
Q77.0 Achondrogenesis	0.023	0.977	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.023	0.977	0.000
Q26.8 Other congenital malformations of great veins	0.023	0.977	0.000
Q26.6 Portal vein-hepatic artery fistula	0.023	0.977	0.000
Q26.5 Anomalous portal venous connexion	0.023	0.977	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.023	0.977	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.023	0.977	0.000
Q26.1 Persistent left superior vena cava	0.023	0.977	0.000
Q26.0 Congenital stenosis of vena cava	0.023	0.977	0.000
Q76.0 Spina bifida occulta	0.023	0.977	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.023	0.977	0.000
Q00-Q07 Congenital malformations of the nervous system	0.023	0.977	0.000
Q55.2 Other congenital malformations of testis and scrotum	0.023	0.977	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.023	0.977	0.000
Q53.0 Ectopic testis	0.023	0.977	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.023	0.977	0.000
Q76.5 Cervical rib	0.023	0.977	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.023	0.977	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.023	0.977	0.000
Q52.4 Other congenital malformations of vagina	0.022	0.977	0.000
Q23.1 Congenital insufficiency of aortic valve	0.023	0.977	0.000
Q35.9 Cleft palate, unspecified	0.022	0.978	0.000
T47.0 Histamine H(2)-receptor antagonists	0.022	0.978	0.000
Q17 Other congenital malformations of ear	0.022	0.978	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.022	0.978	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.022	0.978	0.000
Q20.6 Isomerism of atrial appendages	0.022	0.978	0.000
Q20.5 Discordant atrioventricular connexion	0.022	0.978	0.000
Q20.4 Double inlet ventricle	0.022	0.978	0.000
Q20.3 Discordant ventriculoarterial connexion	0.022	0.978	0.000
Q20.2 Double outlet left ventricle	0.022	0.978	0.000
Q20.1 Double outlet right ventricle	0.022	0.978	0.000
Q20.0 Common arterial trunk	0.022	0.978	0.000
Q28.3 Other malformations of cerebral vessels	0.022	0.978	0.000
Q50.5 Embryonic cyst of broad ligament	0.022	0.978	0.000
Q60-Q64 Congenital malformations of the urinary system	0.022	0.978	0.000
Q52.9 Congenital malformation of female genitalia, unspecified	0.022	0.978	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.022	0.978	0.000
Q52.7 Other congenital malformations of vulva	0.022	0.978	0.000
Q52.6 Congenital malformation of clitoris	0.022	0.978	0.000
Q52.3 Imperforate hymen	0.022	0.978	0.000
Q52.2 Congenital rectovaginal fistula	0.022	0.978	0.000
Q52.0 Congenital absence of vagina	0.022	0.978	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.022	0.978	0.000
Q13 Congenital malformations of anterior segment of eye	0.022	0.978	0.000
Q78.9 Osteochondrodysplasia, unspecified	0.021	0.978	0.000
Q78.8 Other specified osteochondrodysplasias	0.021	0.978	0.000
Q78.6 Multiple congenital exostoses	0.021	0.978	0.000
Q78.5 Metaphyseal dysplasia	0.021	0.978	0.000
Q78.4 Enchondromatosis	0.021	0.978	0.000
Q78.3 Progressive diaphyseal dysplasia	0.021	0.978	0.000
Q78.1 Polyostotic fibrous dysplasia	0.021	0.978	0.000
Q83.8 Other congenital malformations of breast	0.022	0.978	0.000
T47.4 Other laxatives	0.022	0.978	0.000
Q34 Other congenital malformations of respiratory system	0.022	0.978	0.000
Q33 Congenital malformations of lung	0.022	0.978	0.000
Q32 Congenital malformations of trachea and bronchus	0.022	0.978	0.000
Q15 Other congenital malformations of eye	0.021	0.978	0.000
Q18 Other congenital malformations of face and neck	0.021	0.978	0.000
Q80.9 Congenital ichthyosis, unspecified	0.021	0.979	0.000
Q80.8 Other congenital ichthyosis	0.021	0.979	0.000
Q80.4 Harlequin foetus	0.021	0.979	0.000
Q80.3 Congenital bullous ichthyosiform erythroderma	0.021	0.979	0.000
Q80.2 Lamellar ichthyosis	0.021	0.979	0.000
Q80.1 X-linked ichthyosis	0.021	0.979	0.000
Q80.0 Ichthyosis vulgaris	0.021	0.979	0.000
Q81.9 Epidermolysis bullosa, unspecified	0.021	0.979	0.000
Q81.8 Other epidermolysis bullosa	0.021	0.979	0.000
Q81.2 Epidermolysis bullosa dystrophica	0.021	0.979	0.000
Q81.1 Epidermolysis bullosa letalis	0.021	0.979	0.000
Q81.0 Epidermolysis bullosa simplex	0.021	0.979	0.000
Q84.9 Congenital malformation of integument, unspecified	0.021	0.979	0.000
Q84.8 Other specified congenital malformations of integument	0.021	0.979	0.000
Q84.6 Other congenital malformations of nails	0.021	0.979	0.000
Q84.5 Enlarged and hypertrophic nails	0.021	0.979	0.000
Q84.4 Congenital leukonychia	0.021	0.979	0.000
Q84.3 Anonychia	0.021	0.979	0.000
Q84.2 Other congenital malformations of hair	0.021	0.979	0.000
Q84.1 Congenital morphological disturbances of hair, not elsewhere classified	0.021	0.979	0.000
Q84.0 Congenital alopecia	0.021	0.979	0.000
Q86.8 Other congenital malformation syndromes due to known exogenous causes	0.021	0.979	0.000
Q86.2 Dysmorphism due to warfarin	0.021	0.979	0.000
Q86.1 Foetal hydantoin syndrome	0.021	0.979	0.000
Q86.0 Foetal alcohol syndrome (dysmorphic)	0.021	0.979	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.021	0.979	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.021	0.979	0.000
T47.7 Emetics	0.021	0.979	0.000
T47.6 Antidiarrhoeal drugs	0.021	0.979	0.000
T47.5 Digestants	0.021	0.979	0.000
T47.3 Saline and osmotic laxatives	0.021	0.979	0.000
Q30 Congenital malformations of nose	0.021	0.979	0.000
Q82 Other congenital malformations of skin	0.021	0.979	0.000
Q43 Other congenital malformations of intestine	0.021	0.979	0.000
Q14 Congenital malformations of posterior segment of eye	0.021	0.979	0.000
Q52.1 Doubling of vagina	0.021	0.979	0.000
Q12.0 Congenital cataract	0.021	0.979	0.000
Q53.2 Undescended testicle, bilateral	0.020	0.979	0.000
Q83.9 Congenital malformation of breast, unspecified	0.020	0.979	0.000
Q83.2 Absent nipple	0.020	0.979	0.000
Q83.0 Congenital absence of breast with absent nipple	0.020	0.979	0.000
Q53.1 Undescended testicle, unilateral	0.020	0.980	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.020	0.980	0.000
T37.5 Antiviral drugs	0.020	0.980	0.000
T37.4 Anthelminthics	0.020	0.980	0.000
T37.3 Other antiprotozoal drugs	0.020	0.980	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.020	0.980	0.000
T37.1 Antimycobacterial drugs	0.020	0.980	0.000
T37.0 Sulphonamides	0.020	0.980	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.020	0.980	0.000
Q35.8 (Cleft palate, unspecified, bilateral)	0.020	0.980	0.000
Q35.7 Cleft uvula	0.020	0.980	0.000
Q35.6 Cleft palate, medial	0.020	0.980	0.000
Q35.5 Cleft hard palate with cleft soft palate	0.020	0.980	0.000
Q35.4 (Cleft hard palate with cleft soft palate, bilateral)	0.020	0.980	0.000
Q35.3 Cleft soft palate	0.020	0.980	0.000
Q35.2 (Cleft soft palate, bilateral)	0.020	0.980	0.000
Q35.1 Cleft hard palate	0.020	0.980	0.000
Q35.0 (Cleft hard palate, bilateral)	0.020	0.980	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.020	0.980	0.000
T38.9 Other and unspecified hormone antagonists	0.020	0.980	0.000
T38.7 Androgens and anabolic congeners	0.020	0.980	0.000
T38.5 Other oestrogens and progestogens	0.020	0.980	0.000
T38.4 Oral contraceptives	0.020	0.980	0.000
T38.2 Antithyroid drugs	0.020	0.980	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.020	0.980	0.000
Q77.4 Achondroplasia	0.020	0.980	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.020	0.980	0.000
Q39 Congenital malformations of oesophagus	0.020	0.980	0.000
Q31 Congenital malformations of larynx	0.020	0.980	0.000
Q37.9 Unspecified cleft palate with unilateral cleft lip	0.019	0.980	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.019	0.980	0.000
Q83.3 Accessory nipple	0.019	0.981	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.019	0.981	0.000
H11.3 Conjunctival haemorrhage	0.019	0.981	0.000
Q76.1 Klippel-Feil syndrome	0.019	0.981	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.019	0.981	0.000
Q83.1 Accessory breast	0.019	0.981	0.000
Q37.8 Unspecified cleft palate with bilateral cleft lip	0.019	0.981	0.000
Q37.5 Cleft hard and soft palate with unilateral cleft lip	0.019	0.981	0.000
Q37.4 Cleft hard and soft palate with bilateral cleft lip	0.019	0.981	0.000
Q37.3 Cleft soft palate with unilateral cleft lip	0.019	0.981	0.000
Q37.2 Cleft soft palate with bilateral cleft lip	0.019	0.981	0.000
Q37.1 Cleft hard palate with unilateral cleft lip	0.019	0.981	0.000
Q37.0 Cleft hard palate with bilateral cleft lip	0.019	0.981	0.000
T49.9 Topical agent, unspecified	0.019	0.981	0.000
T49.8 Other topical agents	0.019	0.981	0.000
T49.7 Dental drugs, topically applied	0.019	0.981	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.019	0.981	0.000
T49.5 Ophthalmological drugs and preparations	0.019	0.981	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.019	0.981	0.000
T49.3 Emollients, demulcents and protectants	0.019	0.981	0.000
T49.2 Local astringents and local detergents	0.019	0.981	0.000
T49.1 Antipruritics	0.019	0.981	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.018	0.981	0.000
Q52.5 Fusion of labia	0.018	0.981	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.019	0.981	0.000
Q36.9 Cleft lip, unilateral	0.018	0.981	0.000
Q36.1 Cleft lip, medial	0.018	0.981	0.000
Q36.0 Cleft lip, bilateral	0.018	0.981	0.000
T38.0 Glucocorticoids and synthetic analogues	0.018	0.981	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.019	0.981	0.000
T41.5 Therapeutic gases	0.018	0.981	0.000
T41.4 Anaesthetic, unspecified	0.018	0.981	0.000
T41.3 Local anaesthetics	0.018	0.981	0.000
T41.2 Other and unspecified general anaesthetics	0.018	0.981	0.000
T41.1 Intravenous anaesthetics	0.018	0.981	0.000
T41.0 Inhaled anaesthetics	0.018	0.981	0.000
T48.5 Anti-common-cold drugs	0.018	0.982	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.018	0.982	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.018	0.982	0.000
Q12.9 Congenital lens malformation, unspecified	0.018	0.982	0.000
Q12.8 Other congenital lens malformations	0.018	0.982	0.000
Q12.4 Spherophakia	0.018	0.982	0.000
Q12.3 Congenital aphakia	0.018	0.982	0.000
Q12.2 Coloboma of lens	0.018	0.982	0.000
Q12.1 Congenital displaced lens	0.018	0.982	0.000
Q06 Other congenital malformations of spinal cord	0.018	0.982	0.000
Q18.0 Sinus, fistula and cyst of branchial cleft	0.018	0.982	0.000
Q24 Other congenital malformations of heart	0.018	0.982	0.000
T36.0 Penicillins	0.018	0.982	0.000
Q67.5 Congenital deformity of spine	0.018	0.982	0.000
T42.0 Hydantoin derivatives	0.018	0.982	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.018	0.982	0.000
T48.4 Expectorants	0.018	0.982	0.000
T48.3 Antitussives	0.018	0.982	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.018	0.982	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.018	0.982	0.000
T48.0 Oxytocic drugs	0.018	0.982	0.000
Q82.5 Congenital nonneoplastic naevus	0.018	0.982	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.017	0.982	0.000
Q43.8 Other specified congenital malformations of intestine	0.017	0.982	0.000
T36.9 Systemic antibiotic, unspecified	0.017	0.982	0.000
T36.8 Other systemic antibiotics	0.017	0.982	0.000
T36.7 Antifungal antibiotics, systemically used	0.017	0.982	0.000
T36.6 Rifamycins	0.017	0.982	0.000
T36.5 Aminoglycosides	0.017	0.982	0.000
T36.2 Chloramphenicol group	0.017	0.982	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.017	0.982	0.000
T46.1 Calcium-channel blockers	0.017	0.983	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.017	0.983	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.017	0.983	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.017	0.983	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.017	0.983	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.017	0.983	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.017	0.983	0.000
Q01 Encephalocele	0.017	0.983	0.000
Q00 Anencephaly and similar malformations	0.017	0.983	0.000
Q02 Microcephaly	0.017	0.983	0.000
T39.1 4-Aminophenol derivatives	0.017	0.983	0.000
Q43.1 Hirschsprung's disease	0.017	0.983	0.000
Q17.5 Prominent ear	0.017	0.983	0.000
T36.4 Tetracyclines	0.016	0.983	0.000
Q40 Other congenital malformations of upper alimentary tract	0.016	0.983	0.000
Q45 Other congenital malformations of digestive system	0.016	0.984	0.000
T36.3 Macrolides	0.016	0.984	0.000
Q17.9 Congenital malformation of ear, unspecified	0.016	0.984	0.000
Q17.8 Other specified congenital malformations of ear	0.016	0.984	0.000
Q17.4 Misplaced ear	0.016	0.984	0.000
Q17.3 Other misshapen ear	0.016	0.984	0.000
Q17.2 Microtia	0.016	0.984	0.000
Q17.1 Macrotia	0.016	0.984	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations