TreeWAS – Variant ID: rs12595161

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I30-I52 Other forms of heart disease	0.000	0.883	0.117
I51.7 Cardiomegaly	0.000	0.883	0.117
I51 Complications and ill-defined descriptions of heart disease	0.000	0.884	0.116
I50 Heart failure	0.000	0.887	0.113
I34 Nonrheumatic mitral valve disorders	0.000	0.891	0.109
I50.0 Congestive heart failure	0.000	0.891	0.109
I44 Atrioventricular and left bundle-branch block	0.000	0.894	0.106
I34.0 Mitral (valve) insufficiency	0.000	0.899	0.101
I49 Other cardiac arrhythmias	0.000	0.899	0.101
I50.9 Heart failure, unspecified	0.000	0.899	0.101
I33 Acute and subacute endocarditis	0.000	0.900	0.100
I44.2 Atrioventricular block, complete	0.000	0.902	0.098
I51.8 Other ill-defined heart diseases	0.000	0.903	0.097
I46 Cardiac arrest	0.000	0.907	0.093
I31 Other diseases of pericardium	0.000	0.908	0.092
I30 Acute pericarditis	0.000	0.910	0.090
I36 Nonrheumatic tricuspid valve disorders	0.000	0.912	0.088
I44.0 Atrioventricular block, first degree	0.000	0.912	0.088
I51.9 Heart disease, unspecified	0.000	0.912	0.088
I45 Other conduction disorders	0.000	0.913	0.087
I33.0 Acute and subacute infective endocarditis	0.000	0.913	0.087
I38 Endocarditis, valve unspecified	0.000	0.913	0.087
I34.1 Mitral (valve) prolapse	0.000	0.914	0.086
I49.9 Cardiac arrhythmia, unspecified	0.000	0.915	0.085
I44.1 Atrioventricular block, second degree	0.000	0.915	0.085
I52 Other heart disorders in diseases classified elsewhere	0.000	0.916	0.084
I48 Atrial fibrillation and flutter	0.000	0.916	0.084
I43 Cardiomyopathy in diseases classified elsewhere	0.000	0.916	0.084
I41 Myocarditis in diseases classified elsewhere	0.000	0.916	0.084
I40 Acute myocarditis	0.000	0.916	0.084
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.000	0.916	0.084
I32 Pericarditis in diseases classified elsewhere	0.000	0.916	0.084
I49.4 Other and unspecified premature depolarisation	0.000	0.916	0.084
I51.5 Myocardial degeneration	0.000	0.917	0.083
I51.3 Intracardiac thrombosis, not elsewhere classified	0.000	0.917	0.083
I51.2 Rupture of papillary muscle, not elsewhere classified	0.000	0.917	0.083
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.000	0.917	0.083
I46.9 Cardiac arrest, unspecified	0.000	0.917	0.083
I37 Pulmonary valve disorders	0.000	0.918	0.082
I49.0 Ventricular fibrillation and flutter	0.000	0.920	0.080
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.000	0.922	0.078
I34.8 Other nonrheumatic mitral valve disorders	0.000	0.922	0.078
I34.2 Nonrheumatic mitral (valve) stenosis	0.000	0.922	0.078
I49.3 Ventricular premature depolarisation	0.000	0.922	0.078
I31.3 Pericardial effusion (noninflammatory)	0.000	0.923	0.077
I44.6 Other and unspecified fascicular block	0.000	0.923	0.076
I44.5 Left posterior fascicular block	0.000	0.923	0.076
I44.4 Left anterior fascicular block	0.000	0.923	0.076
I51.6 Cardiovascular disease, unspecified	0.000	0.924	0.076
I51.4 Myocarditis, unspecified	0.000	0.926	0.074
I49.2 Junctional premature depolarisation	0.000	0.927	0.072
I44.3 Other and unspecified atrioventricular block	0.000	0.928	0.072
I51.0 Cardiac septal defect, acquired	0.000	0.928	0.072
I33.9 Acute endocarditis, unspecified	0.000	0.928	0.072
I30.9 Acute pericarditis, unspecified	0.000	0.930	0.070
I45.5 Other specified heart block	0.000	0.930	0.069
I49.1 Atrial premature depolarisation	0.000	0.931	0.069
I49.5 Sick sinus syndrome	0.000	0.932	0.068
I45.6 Preexcitation syndrome	0.000	0.932	0.068
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.000	0.932	0.067
I46.1 Sudden cardiac death, so described	0.000	0.933	0.067
I45.1 Other and unspecified right bundle-branch block	0.000	0.934	0.066
I31.8 Other specified diseases of pericardium	0.000	0.934	0.066
I31.2 Haemopericardium, not elsewhere classified	0.000	0.934	0.066
I31.1 Chronic constrictive pericarditis	0.000	0.934	0.066
I31.0 Chronic adhesive pericarditis	0.000	0.934	0.066
I45.9 Conduction disorder, unspecified	0.000	0.934	0.065
I30.8 Other forms of acute pericarditis	0.000	0.935	0.065
I30.1 Infective pericarditis	0.000	0.935	0.065
I30.0 Acute nonspecific idiopathic pericarditis	0.000	0.935	0.065
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.000	0.936	0.063
I36.8 Other nonrheumatic tricuspid valve disorders	0.000	0.936	0.063
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.000	0.936	0.063
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.000	0.936	0.063
I45.4 Nonspecific intraventricular block	0.000	0.937	0.063
I45.0 Right fascicular block	0.000	0.937	0.063
I32.8 Pericarditis in other diseases classified elsewhere	0.000	0.939	0.060
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.939	0.060
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.000	0.939	0.060
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.000	0.939	0.060
I39.4 Multiple valve disorders in diseases classified elsewhere	0.000	0.939	0.060
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.000	0.939	0.060
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.000	0.939	0.060
I39.1 Aortic valve disorders in diseases classified elsewhere	0.000	0.939	0.060
I39.0 Mitral valve disorders in diseases classified elsewhere	0.000	0.939	0.060
I40.9 Acute myocarditis, unspecified	0.000	0.939	0.060
I40.8 Other acute myocarditis	0.000	0.939	0.060
I40.1 Isolated myocarditis	0.000	0.939	0.060
I40.0 Infective myocarditis	0.000	0.939	0.060
I41.8 Myocarditis in other diseases classified elsewhere	0.000	0.939	0.060
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.939	0.060
I41.1 Myocarditis in viral diseases classified elsewhere	0.000	0.939	0.060
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.000	0.939	0.060
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.000	0.939	0.060
I43.2 Cardiomyopathy in nutritional diseases	0.000	0.939	0.060
I43.1 Cardiomyopathy in metabolic diseases	0.000	0.939	0.060
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.000	0.939	0.060
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.000	0.939	0.060
I48.4 Atypical atrial flutter	0.000	0.939	0.060
I48.3 Typical atrial flutter	0.000	0.939	0.060
I48.2 Chronic atrial fibrillation	0.000	0.939	0.060
I48.1 Persistent atrial fibrillation	0.000	0.939	0.060
I48.0 Paroxysmal atrial fibrillation	0.000	0.939	0.060
I52.8 Other heart disorders in other diseases classified elsewhere	0.000	0.939	0.060
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.939	0.060
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.000	0.939	0.060
I45.2 Bifascicular block	0.000	0.940	0.060
I31.9 Disease of pericardium, unspecified	0.000	0.940	0.060
I37.9 Pulmonary valve disorder, unspecified	0.000	0.941	0.059
I37.8 Other pulmonary valve disorders	0.000	0.941	0.059
I37.2 Pulmonary valve stenosis with insufficiency	0.000	0.941	0.059
I37.0 Pulmonary valve stenosis	0.000	0.941	0.059
I47 Paroxysmal tachycardia	0.000	0.942	0.058
I45.3 Trifascicular block	0.000	0.942	0.058
I49.8 Other specified cardiac arrhythmias	0.000	0.943	0.057
I37.1 Pulmonary valve insufficiency	0.000	0.943	0.056
I42 Cardiomyopathy	0.000	0.945	0.055
I44.7 Left bundle-branch block, unspecified	0.000	0.947	0.053
I45.8 Other specified conduction disorders	0.000	0.947	0.053
I46.0 Cardiac arrest with successful resuscitation	0.000	0.950	0.050
I50.1 Left ventricular failure	0.000	0.956	0.044
I42.2 Other hypertrophic cardiomyopathy	0.000	0.959	0.041
I47.0 Reentry ventricular arrhythmia	0.000	0.959	0.041
I47.9 Paroxysmal tachycardia, unspecified	0.000	0.960	0.040
I42.7 Cardiomyopathy due to drugs and other external agents	0.000	0.961	0.039
I42.6 Alcoholic cardiomyopathy	0.000	0.961	0.039
I42.5 Other restrictive cardiomyopathy	0.000	0.961	0.039
I42.4 Endocardial fibroelastosis	0.000	0.961	0.039
I42.3 Endomyocardial (eosinophilic) disease	0.000	0.961	0.039
I47.2 Ventricular tachycardia	0.000	0.962	0.038
I35 Nonrheumatic aortic valve disorders	0.000	0.962	0.038
I42.8 Other cardiomyopathies	0.000	0.963	0.036
I42.9 Cardiomyopathy, unspecified	0.000	0.963	0.037
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.964	0.036
I47.1 Supraventricular tachycardia	0.000	0.969	0.031
I35.8 Other aortic valve disorders	0.000	0.971	0.029
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.974	0.026
I42.0 Dilated cardiomyopathy	0.000	0.975	0.025
I35.9 Aortic valve disorder, unspecified	0.000	0.975	0.025
I35.1 Aortic (valve) insufficiency	0.000	0.977	0.022
E66.9 Obesity, unspecified	0.000	0.984	0.016
E66.8 Other obesity	0.000	0.985	0.015
E66 Obesity	0.000	0.985	0.015
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.989	0.011
E66.1 Drug-induced obesity	0.000	0.989	0.011
E66.0 Obesity due to excess calories	0.000	0.989	0.011
E65-E68 Obesity and other hyperalimentation	0.000	0.992	0.008
I35.0 Aortic (valve) stenosis	0.000	0.992	0.007
L40.5 Arthropathic psoriasis	0.000	0.992	0.008
J31.0 Chronic rhinitis	0.007	0.993	0.000
L40.9 Psoriasis, unspecified	0.000	0.993	0.007
E65 Localised adiposity	0.000	0.994	0.006
E67 Other hyperalimentation	0.000	0.994	0.006
E68 Sequelae of hyperalimentation	0.000	0.994	0.006
L40 Psoriasis	0.000	0.994	0.006
E03.9 Hypothyroidism, unspecified	0.000	0.994	0.006
J32.9 Chronic sinusitis, unspecified	0.006	0.994	0.000
K31.7 Polyp of stomach and duodenum	0.000	0.994	0.006
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.005	0.994	0.000
J32 Chronic sinusitis	0.005	0.995	0.000
E03 Other hypothyroidism	0.000	0.995	0.005
J32.0 Chronic maxillary sinusitis	0.005	0.995	0.000
E67.8 Other specified hyperalimentation	0.000	0.995	0.005
E67.3 Hypervitaminosis D	0.000	0.995	0.005
E67.2 Megavitamin-B6 syndrome	0.000	0.995	0.005
E67.1 Hypercarotenaemia	0.000	0.995	0.005
E67.0 Hypervitaminosis A	0.000	0.995	0.005
L40.8 Other psoriasis	0.000	0.995	0.005
L40.4 Guttate psoriasis	0.000	0.995	0.005
L40.3 Pustulosis palmaris et plantaris	0.000	0.995	0.005
L40.2 Acrodermatitis continua	0.000	0.995	0.005
L40.1 Generalised pustular psoriasis	0.000	0.995	0.005
L40.0 Psoriasis vulgaris	0.000	0.995	0.005
J36 Peritonsillar abscess	0.005	0.995	0.000
E00-E07 Disorders of thyroid gland	0.000	0.996	0.004
J30-J39 Other diseases of upper respiratory tract	0.004	0.996	0.000
J31.2 Chronic pharyngitis	0.004	0.996	0.000
J31.1 Chronic nasopharyngitis	0.004	0.996	0.000
J32.4 Chronic pansinusitis	0.004	0.996	0.000
C32.0 Glottis	0.004	0.996	0.000
J32.3 Chronic sphenoidal sinusitis	0.004	0.996	0.000
J32.1 Chronic frontal sinusitis	0.004	0.996	0.000
E03.8 Other specified hypothyroidism	0.000	0.996	0.004
E03.5 Myxoedema coma	0.000	0.996	0.004
E03.4 Atrophy of thyroid (acquired)	0.000	0.996	0.004
E03.3 Postinfectious hypothyroidism	0.000	0.996	0.004
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.996	0.004
E03.1 Congenital hypothyroidism without goitre	0.000	0.996	0.004
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.996	0.004
J35.8 Other chronic diseases of tonsils and adenoids	0.004	0.996	0.000
J32.2 Chronic ethmoidal sinusitis	0.004	0.996	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.996	0.004
J35 Chronic diseases of tonsils and adenoids	0.004	0.996	0.000
J39 Other diseases of upper respiratory tract	0.004	0.996	0.000
J32.8 Other chronic sinusitis	0.003	0.996	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.996	0.004
E05.9 Thyrotoxicosis, unspecified	0.000	0.996	0.004
E20-E35 Disorders of other endocrine glands	0.000	0.997	0.003
H43.8 Other disorders of vitreous body	0.000	0.997	0.003
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.997	0.003
E00 Congenital iodine-deficiency syndrome	0.000	0.997	0.003
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.997	0.003
E27 Other disorders of adrenal gland	0.000	0.997	0.003
E06 Thyroiditis	0.000	0.997	0.003
E27.1 Primary adrenocortical insufficiency	0.000	0.997	0.003
J37 Chronic laryngitis and laryngotracheitis	0.003	0.997	0.000
C32.9 Larynx, unspecified	0.003	0.997	0.000
E23 Hypofunction and other disorders of pituitary gland	0.000	0.997	0.003
C32 Malignant neoplasm of larynx	0.003	0.997	0.000
E04 Other non-toxic goitre	0.000	0.997	0.003
E53.8 Deficiency of other specified B group vitamins	0.000	0.997	0.003
E50-E64 Other nutritional deficiencies	0.000	0.997	0.003
E07 Other disorders of thyroid	0.000	0.997	0.003
E53 Deficiency of other B group vitamins	0.000	0.997	0.003
J39.2 Other diseases of pharynx	0.003	0.997	0.000
J39.8 Other specified diseases of upper respiratory tract	0.003	0.997	0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.000	0.997	0.003
E23.0 Hypopituitarism	0.000	0.997	0.003
E22 Hyperfunction of pituitary gland	0.000	0.997	0.003
E05.8 Other thyrotoxicosis	0.000	0.997	0.003
E05.5 Thyroid crisis or storm	0.000	0.997	0.003
E05.4 Thyrotoxicosis factitia	0.000	0.997	0.003
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.997	0.003
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.997	0.003
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.997	0.003
J35.9 Chronic disease of tonsils and adenoids, unspecified	0.003	0.997	0.000
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids	0.003	0.997	0.000
J35.2 Hypertrophy of adenoids	0.003	0.997	0.000
J35.1 Hypertrophy of tonsils	0.003	0.997	0.000
R50.0 Fever with chills	0.003	0.997	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.997	0.003
E29 Testicular dysfunction	0.000	0.997	0.003
J39.9 Disease of upper respiratory tract, unspecified	0.003	0.997	0.000
J39.3 Upper respiratory tract hypersensitivity reaction, site unspecified	0.003	0.997	0.000
J39.1 Other abscess of pharynx	0.003	0.997	0.000
J39.0 Retropharyngeal and parapharyngeal abscess	0.003	0.997	0.000
Z88.2 Personal history of allergy to sulphonamides	0.000	0.997	0.003
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.997	0.003
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.997	0.003
E04.1 Non-toxic single thyroid nodule	0.000	0.997	0.003
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.997	0.003
E34 Other endocrine disorders	0.000	0.997	0.003
E32 Diseases of thymus	0.000	0.997	0.003
E31 Polyglandular dysfunction	0.000	0.997	0.003
E30 Disorders of puberty, not elsewhere classified	0.000	0.997	0.003
E25 Adrenogenital disorders	0.000	0.997	0.003
E24 Cushing's syndrome	0.000	0.997	0.003
E20 Hypoparathyroidism	0.000	0.997	0.003
E04.2 Non-toxic multinodular goitre	0.000	0.997	0.003
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.000	0.997	0.003
C32.1 Supraglottis	0.003	0.997	0.000
E06.3 Autoimmune thyroiditis	0.000	0.997	0.003
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.003	0.997	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.997	0.003
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.997	0.002
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.997	0.002
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.997	0.002
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.997	0.002
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.997	0.002
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.997	0.002
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.997	0.002
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.997	0.002
E40-E46 Malnutrition	0.000	0.997	0.003
E27.9 Disorder of adrenal gland, unspecified	0.000	0.997	0.002
E27.5 Adrenomedullary hyperfunction	0.000	0.997	0.002
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.997	0.002
E27.2 Addisonian crisis	0.000	0.997	0.002
E27.0 Other adrenocortical overactivity	0.000	0.997	0.002
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.003	0.997	0.000
Z88.6 Personal history of allergy to analgesic agent	0.000	0.997	0.003
E06.5 Other chronic thyroiditis	0.000	0.997	0.002
E06.4 Drug-induced thyroiditis	0.000	0.997	0.002
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.997	0.002
E06.1 Subacute thyroiditis	0.000	0.997	0.002
E06.0 Acute thyroiditis	0.000	0.997	0.002
M25.57 Pain in joint (Ankle and foot)	0.003	0.997	0.000
E27.8 Other specified disorders of adrenal gland	0.000	0.997	0.002
E23.2 Diabetes insipidus	0.000	0.997	0.002
J37.1 Chronic laryngotracheitis	0.002	0.997	0.000
R26.8 Other and unspecified abnormalities of gait and mobility	0.003	0.997	0.000
E23.7 Disorder of pituitary gland, unspecified	0.000	0.997	0.002
E23.6 Other disorders of pituitary gland	0.000	0.997	0.002
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.997	0.002
E23.1 Drug-induced hypopituitarism	0.000	0.997	0.002
C32.8 Overlapping lesion of larynx	0.002	0.997	0.000
C32.3 Laryngeal cartilage	0.002	0.997	0.000
C32.2 Subglottis	0.002	0.997	0.000
D22.5 Melanocytic naevi of trunk	0.000	0.997	0.003
K83.8 Other specified diseases of biliary tract	0.003	0.997	0.000
E04.8 Other specified non-toxic goitre	0.000	0.997	0.002
E04.0 Non-toxic diffuse goitre	0.000	0.997	0.002
E29.1 Testicular hypofunction	0.000	0.997	0.002
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances	0.000	0.997	0.002
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.997	0.002
E63 Other nutritional deficiencies	0.000	0.997	0.002
E56 Other vitamin deficiencies	0.000	0.997	0.002
E51 Thiamine deficiency	0.000	0.997	0.002
E50 Vitamin A deficiency	0.000	0.997	0.002
E60 Dietary zinc deficiency	0.000	0.997	0.002
E59 Dietary selenium deficiency	0.000	0.997	0.002
E58 Dietary calcium deficiency	0.000	0.997	0.002
E54 Ascorbic acid deficiency	0.000	0.997	0.002
E52 Niacin deficiency [pellagra]	0.000	0.997	0.002
E07.8 Other specified disorders of thyroid	0.000	0.997	0.002
E07.1 Dyshormogenetic goitre	0.000	0.997	0.002
E07.0 Hypersecretion of calcitonin	0.000	0.997	0.002
J37.0 Chronic laryngitis	0.002	0.997	0.000
N85.2 Hypertrophy of uterus	0.002	0.997	0.000
E06.9 Thyroiditis, unspecified	0.000	0.998	0.002
E53.9 Vitamin B deficiency, unspecified	0.000	0.998	0.002
E53.1 Pyridoxine deficiency	0.000	0.998	0.002
E53.0 Riboflavin deficiency	0.000	0.998	0.002
E28 Ovarian dysfunction	0.000	0.998	0.002
J38.3 Other diseases of vocal cords	0.002	0.998	0.000
E26 Hyperaldosteronism	0.000	0.998	0.002
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.998	0.002
E22.8 Other hyperfunction of pituitary gland	0.000	0.998	0.002
E22.1 Hyperprolactinaemia	0.000	0.998	0.002
J38.2 Nodules of vocal cords	0.002	0.998	0.000
J38.5 Laryngeal spasm	0.002	0.998	0.000
R50.9 Fever, unspecified	0.002	0.998	0.000
Z88.4 Personal history of allergy to anaesthetic agent	0.000	0.998	0.002
E29.9 Testicular dysfunction, unspecified	0.000	0.998	0.002
E29.8 Other testicular dysfunction	0.000	0.998	0.002
E29.0 Testicular hyperfunction	0.000	0.998	0.002
Z88.1 Personal history of allergy to other antibiotic agents	0.000	0.998	0.002
E55 Vitamin D deficiency	0.000	0.998	0.002
E61 Deficiency of other nutrient elements	0.000	0.998	0.002
J30 Vasomotor and allergic rhinitis	0.002	0.998	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.998	0.002
E20.9 Hypoparathyroidism, unspecified	0.000	0.998	0.002
E20.8 Other hypoparathyroidism	0.000	0.998	0.002
E20.1 Pseudohypoparathyroidism	0.000	0.998	0.002
E20.0 Idiopathic hypoparathyroidism	0.000	0.998	0.002
E24.9 Cushing's syndrome, unspecified	0.000	0.998	0.002
E24.8 Other Cushing's syndrome	0.000	0.998	0.002
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.998	0.002
E24.3 Ectopic ACTH syndrome	0.000	0.998	0.002
E24.2 Drug-induced Cushing's syndrome	0.000	0.998	0.002
E24.1 Nelson's syndrome	0.000	0.998	0.002
E24.0 Pituitary-dependent Cushing's disease	0.000	0.998	0.002
E25.9 Adrenogenital disorder, unspecified	0.000	0.998	0.002
E25.8 Other adrenogenital disorders	0.000	0.998	0.002
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.998	0.002
E30.9 Disorder of puberty, unspecified	0.000	0.998	0.002
E30.8 Other disorders of puberty	0.000	0.998	0.002
E30.1 Precocious puberty	0.000	0.998	0.002
E30.0 Delayed puberty	0.000	0.998	0.002
E31.9 Polyglandular dysfunction, unspecified	0.000	0.998	0.002
E31.8 Other polyglandular dysfunction	0.000	0.998	0.002
E31.1 Polyglandular hyperfunction	0.000	0.998	0.002
E31.0 Autoimmune polyglandular failure	0.000	0.998	0.002
E32.9 Disease of thymus, unspecified	0.000	0.998	0.002
E32.8 Other diseases of thymus	0.000	0.998	0.002
E32.1 Abscess of thymus	0.000	0.998	0.002
E32.0 Persistent hyperplasia of thymus	0.000	0.998	0.002
E34.9 Endocrine disorder, unspecified	0.000	0.998	0.002
E34.8 Other specified endocrine disorders	0.000	0.998	0.002
E34.5 Androgen resistance syndrome	0.000	0.998	0.002
E34.4 Constitutional tall stature	0.000	0.998	0.002
E34.3 Short stature, not elsewhere classified	0.000	0.998	0.002
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.998	0.002
E34.1 Other hypersecretion of intestinal hormones	0.000	0.998	0.002
E34.0 Carcinoid syndrome	0.000	0.998	0.002
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.998	0.002
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.998	0.002
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.998	0.002
J35.0 Chronic tonsillitis	0.002	0.998	0.000
J38.6 Stenosis of larynx	0.002	0.998	0.000
E15 Nondiabetic hypoglycaemic coma	0.000	0.998	0.002
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.998	0.002
E45 Retarded development following protein-energy malnutrition	0.000	0.998	0.002
E43 Unspecified severe protein-energy malnutrition	0.000	0.998	0.002
E42 Marasmic kwashiorkor	0.000	0.998	0.002
E41 Nutritional marasmus	0.000	0.998	0.002
E40 Kwashiorkor	0.000	0.998	0.002
E07.9 Disorder of thyroid, unspecified	0.000	0.998	0.002
E22.0 Acromegaly and pituitary gigantism	0.000	0.998	0.002
Z88.3 Personal history of allergy to other anti-infective agents	0.000	0.998	0.002
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.000	0.998	0.002
G95.2 Cord compression, unspecified	0.002	0.998	0.000
G95.8 Other specified diseases of spinal cord	0.002	0.998	0.000
K83.0 Cholangitis	0.002	0.998	0.000
E50.9 Vitamin A deficiency, unspecified	0.000	0.998	0.002
E50.8 Other manifestations of vitamin A deficiency	0.000	0.998	0.002
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.998	0.002
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.998	0.002
E50.5 Vitamin A deficiency with night blindness	0.000	0.998	0.002
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.998	0.002
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.998	0.002
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.998	0.002
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.998	0.002
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.998	0.002
E51.9 Thiamine deficiency, unspecified	0.000	0.998	0.002
E51.8 Other manifestations of thiamine deficiency	0.000	0.998	0.002
E51.2 Wernicke's encephalopathy	0.000	0.998	0.002
E51.1 Beriberi	0.000	0.998	0.002
E56.9 Vitamin deficiency, unspecified	0.000	0.998	0.002
E56.8 Deficiency of other vitamins	0.000	0.998	0.002
E56.1 Deficiency of vitamin K	0.000	0.998	0.002
E56.0 Deficiency of vitamin E	0.000	0.998	0.002
E63.9 Nutritional deficiency, unspecified	0.000	0.998	0.002
E63.8 Other specified nutritional deficiencies	0.000	0.998	0.002
E63.1 Imbalance of constituents of food intake	0.000	0.998	0.002
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.998	0.002
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.998	0.002
E64.8 Sequelae of other nutritional deficiencies	0.000	0.998	0.002
E64.3 Sequelae of rickets	0.000	0.998	0.002
E64.2 Sequelae of vitamin C deficiency	0.000	0.998	0.002
E64.1 Sequelae of vitamin A deficiency	0.000	0.998	0.002
E64.0 Sequelae of protein-energy malnutrition	0.000	0.998	0.002
K83 Other diseases of biliary tract	0.002	0.998	0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock	0.002	0.998	0.000
D22.1 Melanocytic naevi of eyelid, including canthus	0.000	0.998	0.002
E26.9 Hyperaldosteronism, unspecified	0.000	0.998	0.002
E26.8 Other hyperaldosteronism	0.000	0.998	0.002
E26.1 Secondary hyperaldosteronism	0.000	0.998	0.002
E28.9 Ovarian dysfunction, unspecified	0.000	0.998	0.002
E28.8 Other ovarian dysfunction	0.000	0.998	0.002
E28.3 Primary ovarian failure	0.000	0.998	0.002
E28.1 Androgen excess	0.000	0.998	0.002
E28.0 Oestrogen excess	0.000	0.998	0.002
G95.9 Disease of spinal cord, unspecified	0.002	0.998	0.000
H43 Disorders of vitreous body	0.000	0.998	0.002
E16 Other disorders of pancreatic internal secretion	0.000	0.998	0.002
E46 Unspecified protein-energy malnutrition	0.000	0.998	0.002
H43.3 Other vitreous opacities	0.000	0.998	0.002
J38.4 Oedema of larynx	0.002	0.998	0.000
Z88.5 Personal history of allergy to narcotic agent	0.000	0.998	0.002
G95 Other diseases of spinal cord	0.002	0.998	0.000
R50 Fever of unknown origin	0.002	0.998	0.000
M25.77 Osteophyte (Ankle and foot)	0.002	0.998	0.000
E55.0 Rickets, active	0.000	0.998	0.002
E61.9 Deficiency of nutrient element, unspecified	0.000	0.998	0.002
E61.8 Deficiency of other specified nutrient elements	0.000	0.998	0.002
E61.7 Deficiency of multiple nutrient elements	0.000	0.998	0.002
E61.6 Vanadium deficiency	0.000	0.998	0.002
E61.5 Molybdenum deficiency	0.000	0.998	0.002
E61.4 Chromium deficiency	0.000	0.998	0.002
E61.3 Manganese deficiency	0.000	0.998	0.002
E61.2 Magnesium deficiency	0.000	0.998	0.002
E61.0 Copper deficiency	0.000	0.998	0.002
D22.6 Melanocytic naevi of upper limb, including shoulder	0.000	0.998	0.002
Z88.0 Personal history of allergy to penicillin	0.000	0.998	0.002
J30.2 Other seasonal allergic rhinitis	0.002	0.998	0.000
J30.0 Vasomotor rhinitis	0.002	0.998	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.998	0.002
E21.4 Other specified disorders of parathyroid gland	0.000	0.998	0.002
E21.2 Other hyperparathyroidism	0.000	0.998	0.002
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.998	0.002
C73 Malignant neoplasm of thyroid gland	0.002	0.998	0.000
J34 Other disorders of nose and nasal sinuses	0.002	0.998	0.000
E44.1 Mild protein-energy malnutrition	0.000	0.998	0.002
E44.0 Moderate protein-energy malnutrition	0.000	0.998	0.002
K83.1 Obstruction of bile duct	0.002	0.998	0.000
Z88.7 Personal history of allergy to serum and vaccine	0.000	0.998	0.002
G95.1 Vascular myelopathies	0.002	0.998	0.000
J30.4 Allergic rhinitis, unspecified	0.002	0.998	0.000
J34.0 Abscess, furuncle and carbuncle of nose	0.002	0.998	0.000
J38.7 Other diseases of larynx	0.002	0.998	0.000
E26.0 Primary hyperaldosteronism	0.000	0.998	0.001
J38.0 Paralysis of vocal cords and larynx	0.002	0.998	0.000
E10.3 With ophthalmic complications	0.002	0.998	0.000
E28.2 Polycystic ovarian syndrome	0.000	0.998	0.001
K83.9 Disease of biliary tract, unspecified	0.002	0.998	0.000
K83.5 Biliary cyst	0.002	0.998	0.000
K83.4 Spasm of sphincter of Oddi	0.002	0.998	0.000
K83.3 Fistula of bile duct	0.002	0.998	0.000
K83.2 Perforation of bile duct	0.002	0.998	0.000
D22 Melanocytic naevi	0.000	0.998	0.002
E10.1 With ketoacidosis	0.002	0.998	0.000
D22.7 Melanocytic naevi of lower limb, including hip	0.000	0.998	0.002
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.998	0.002
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.998	0.002
E16.4 Abnormal secretion of gastrin	0.000	0.998	0.002
E16.3 Increased secretion of glucagon	0.000	0.998	0.002
E16.1 Other hypoglycaemia	0.000	0.998	0.002
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.998	0.002
H43.9 Disorder of vitreous body, unspecified	0.000	0.998	0.002
H43.2 Crystalline deposits in vitreous body	0.000	0.998	0.002
H43.0 Vitreous prolapse	0.000	0.998	0.002
S32.00 Fracture of lumbar vertebra (closed)	0.000	0.998	0.002
E55.9 Vitamin D deficiency, unspecified	0.000	0.998	0.002
E61.1 Iron deficiency	0.000	0.998	0.001
F20.0 Paranoid schizophrenia	0.002	0.998	0.000
J30.3 Other allergic rhinitis	0.001	0.998	0.000
J33 Nasal polyp	0.002	0.998	0.000
S82.20 Fracture of shaft of tibia (closed)	0.000	0.998	0.002
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.000	0.998	0.002
G95.0 Syringomyelia and syringobulbia	0.002	0.998	0.000
J38.1 Polyp of vocal cord and larynx	0.001	0.998	0.000
R50.2 Drug-induced fever	0.002	0.998	0.000
R50.1 Persistent fever	0.002	0.998	0.000
K31 Other diseases of stomach and duodenum	0.000	0.998	0.002
L40-L45 Papulosquamous disorders	0.000	0.998	0.002
J93.1 Other spontaneous pneumothorax	0.002	0.998	0.000
E21.3 Hyperparathyroidism, unspecified	0.000	0.998	0.001
D63.0 Anaemia in neoplastic disease	0.002	0.998	0.000
E10.4 With neurological complications	0.002	0.998	0.000
E21.0 Primary hyperparathyroidism	0.000	0.998	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations