TreeWAS – Variant ID: rs12599426

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K50.0 Crohn's disease of small intestine	0.000	0.975	0.025
K50.9 Crohn's disease, unspecified	0.000	0.984	0.016
K50 Crohn's disease [regional enteritis]	0.000	0.985	0.014
G35 Multiple sclerosis	0.000	0.991	0.009
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.007	0.993	0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.007	0.993	0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.007	0.993	0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.007	0.993	0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.006	0.994	0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.006	0.994	0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.006	0.994	0.000
T83.0 Mechanical complication of urinary (indwelling) catheter	0.006	0.994	0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.006	0.994	0.000
K50.1 Crohn's disease of large intestine	0.000	0.994	0.006
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.994	0.006
N32.0 Bladder-neck obstruction	0.006	0.994	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.006	0.994	0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.006	0.994	0.000
K50.8 Other Crohn's disease	0.001	0.994	0.005
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.006	0.994	0.000
G37 Other demyelinating diseases of central nervous system	0.000	0.994	0.006
Q66.8 Other congenital deformities of feet	0.006	0.994	0.000
T83.3 Mechanical complication of intra-uterine contraceptive device	0.005	0.995	0.000
T83.2 Mechanical complication of graft of urinary organ	0.005	0.995	0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.005	0.995	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.000	0.995	0.005
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.005	0.995	0.000
O70.0 First degree perineal laceration during delivery	0.000	0.995	0.005
Q66 Congenital deformities of feet	0.005	0.995	0.000
Z90.2 Acquired absence of lung [part of]	0.005	0.995	0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.005	0.995	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.995	0.005
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.004	0.996	0.000
G36 Other acute disseminated demyelination	0.000	0.996	0.004
G37.8 Other specified demyelinating diseases of central nervous system	0.000	0.996	0.004
G37.5 Concentric sclerosis [Balo]	0.000	0.996	0.004
G37.4 Subacute necrotising myelitis	0.000	0.996	0.004
G37.2 Central pontine myelinolysis	0.000	0.996	0.004
G37.1 Central demyelination of corpus callosum	0.000	0.996	0.004
G37.0 Diffuse sclerosis	0.000	0.996	0.004
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.004	0.996	0.000
N36.8 Other specified disorders of urethra	0.004	0.996	0.000
Q78 Other osteochondrodysplasias	0.004	0.996	0.000
Q74 Other congenital malformations of limb(s)	0.004	0.996	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.004	0.996	0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.004	0.996	0.000
G25.8 Other specified extrapyramidal and movement disorders	0.000	0.996	0.004
M41.9 Scoliosis, unspecified	0.004	0.996	0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.004	0.996	0.000
Q78.0 Osteogenesis imperfecta	0.004	0.996	0.000
O70.2 Third degree perineal laceration during delivery	0.000	0.996	0.004
Q66.9 Congenital deformity of feet, unspecified	0.004	0.996	0.000
Q66.7 Pes cavus	0.004	0.996	0.000
Q66.6 Other congenital valgus deformities of feet	0.004	0.996	0.000
Q66.5 Congenital pes planus	0.004	0.996	0.000
Q66.4 Talipes calcaneovalgus	0.004	0.996	0.000
Q66.3 Other congenital varus deformities of feet	0.004	0.996	0.000
Q66.2 Metatarsus varus	0.004	0.996	0.000
Q66.1 Talipes calcaneovarus	0.004	0.996	0.000
Q66.0 Talipes equinovarus	0.004	0.996	0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.004	0.996	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.004	0.996	0.000
Q76 Congenital malformations of spine and bony thorax	0.004	0.996	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.004	0.996	0.000
H36.0 Diabetic retinopathy	0.000	0.996	0.004
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.003	0.996	0.000
O70 Perineal laceration during delivery	0.000	0.996	0.004
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.003	0.997	0.000
Q75 Other congenital malformations of skull and face bones	0.003	0.997	0.000
Q73 Reduction defects of unspecified limb	0.003	0.997	0.000
Q72 Reduction defects of lower limb	0.003	0.997	0.000
Q71 Reduction defects of upper limb	0.003	0.997	0.000
Q70 Syndactyly	0.003	0.997	0.000
Q69 Polydactyly	0.003	0.997	0.000
Q68 Other congenital musculoskeletal deformities	0.003	0.997	0.000
G36.9 Acute disseminated demyelination, unspecified	0.000	0.997	0.003
G36.8 Other specified acute disseminated demyelination	0.000	0.997	0.003
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.000	0.997	0.003
G36.0 Neuromyelitis optica [Devic]	0.000	0.997	0.003
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.003	0.997	0.000
Q65 Congenital deformities of hip	0.003	0.997	0.000
Q74.9 Unspecified congenital malformation of limb(s)	0.003	0.997	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.003	0.997	0.000
Q74.3 Arthrogryposis multiplex congenita	0.003	0.997	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.003	0.997	0.000
Q74.1 Congenital malformation of knee	0.003	0.997	0.000
Q78.9 Osteochondrodysplasia, unspecified	0.003	0.997	0.000
Q78.8 Other specified osteochondrodysplasias	0.003	0.997	0.000
Q78.6 Multiple congenital exostoses	0.003	0.997	0.000
Q78.5 Metaphyseal dysplasia	0.003	0.997	0.000
Q78.4 Enchondromatosis	0.003	0.997	0.000
Q78.3 Progressive diaphyseal dysplasia	0.003	0.997	0.000
Q78.2 Osteopetrosis	0.003	0.997	0.000
Q78.1 Polyostotic fibrous dysplasia	0.003	0.997	0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.003	0.997	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.003	0.997	0.000
M41.94 Scoliosis, unspecified (Thoracic region)	0.003	0.997	0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.003	0.997	0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.003	0.997	0.000
M41.92 Scoliosis, unspecified (Cervical region)	0.003	0.997	0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.003	0.997	0.000
S92.30 Fracture of metatarsal bone (closed)	0.003	0.997	0.000
Q79.6 Ehlers-Danlos syndrome	0.003	0.997	0.000
Z80.4 Family history of malignant neoplasm of genital organs	0.003	0.997	0.000
C43.6 Malignant melanoma of upper limb, including shoulder	0.003	0.997	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.003	0.997	0.000
Q76.8 Other congenital malformations of bony thorax	0.003	0.997	0.000
Q76.7 Congenital malformation of sternum	0.003	0.997	0.000
Q76.6 Other congenital malformations of ribs	0.003	0.997	0.000
Q76.5 Cervical rib	0.003	0.997	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.003	0.997	0.000
Q76.2 Congenital spondylolisthesis	0.003	0.997	0.000
Q76.1 Klippel-Feil syndrome	0.003	0.997	0.000
O41.0 Oligohydramnios	0.003	0.997	0.000
Q76.0 Spina bifida occulta	0.003	0.997	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.003	0.997	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.003	0.997	0.000
Q79.5 Other congenital malformations of abdominal wall	0.003	0.997	0.000
Q79.4 Prune belly syndrome	0.003	0.997	0.000
Q79.3 Gastroschisis	0.003	0.997	0.000
Q79.2 Exomphalos	0.003	0.997	0.000
Q79.1 Other congenital malformations of diaphragm	0.003	0.997	0.000
Q79.0 Congenital diaphragmatic hernia	0.003	0.997	0.000
S92.00 Fracture of calcaneus (closed)	0.003	0.997	0.000
O70.3 Fourth degree perineal laceration during delivery	0.000	0.997	0.003
Q68.8 Other specified congenital musculoskeletal deformities	0.003	0.997	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.003	0.997	0.000
Q68.4 Congenital bowing of tibia and fibula	0.003	0.997	0.000
Q68.3 Congenital bowing of femur	0.003	0.997	0.000
Q68.2 Congenital deformity of knee	0.003	0.997	0.000
Q68.1 Congenital deformity of hand	0.003	0.997	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.003	0.997	0.000
Q69.9 Polydactyly, unspecified	0.003	0.997	0.000
Q69.2 Accessory toe(s)	0.003	0.997	0.000
Q69.1 Accessory thumb(s)	0.003	0.997	0.000
Q69.0 Accessory finger(s)	0.003	0.997	0.000
Q70.9 Syndactyly, unspecified	0.003	0.997	0.000
Q70.4 Polysyndactyly	0.003	0.997	0.000
Q70.3 Webbed toes	0.003	0.997	0.000
Q70.2 Fused toes	0.003	0.997	0.000
Q70.1 Webbed fingers	0.003	0.997	0.000
Q70.0 Fused fingers	0.003	0.997	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.003	0.997	0.000
Q71.8 Other reduction defects of upper limb(s)	0.003	0.997	0.000
Q71.6 Lobster-claw hand	0.003	0.997	0.000
Q71.5 Longitudinal reduction defect of ulna	0.003	0.997	0.000
Q71.4 Longitudinal reduction defect of radius	0.003	0.997	0.000
Q71.3 Congenital absence of hand and finger(s)	0.003	0.997	0.000
Q71.2 Congenital absence of both forearm and hand	0.003	0.997	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.003	0.997	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.003	0.997	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.003	0.997	0.000
Q72.8 Other reduction defects of lower limb(s)	0.003	0.997	0.000
Q72.7 Split foot	0.003	0.997	0.000
Q72.6 Longitudinal reduction defect of fibula	0.003	0.997	0.000
Q72.5 Longitudinal reduction defect of tibia	0.003	0.997	0.000
Q72.4 Longitudinal reduction defect of femur	0.003	0.997	0.000
Q72.3 Congenital absence of foot and toe(s)	0.003	0.997	0.000
Q72.2 Congenital absence of both lower leg and foot	0.003	0.997	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.003	0.997	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.003	0.997	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.003	0.997	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.003	0.997	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.003	0.997	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.003	0.997	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.003	0.997	0.000
Q75.5 Oculomandibular dysostosis	0.003	0.997	0.000
Q75.4 Mandibulofacial dysostosis	0.003	0.997	0.000
Q75.3 Macrocephaly	0.003	0.997	0.000
Q75.2 Hypertelorism	0.003	0.997	0.000
Q75.1 Craniofacial dysostosis	0.003	0.997	0.000
Q75.0 Craniosynostosis	0.003	0.997	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.003	0.997	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.003	0.997	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.003	0.997	0.000
Q77.6 Chondroectodermal dysplasia	0.003	0.997	0.000
Q77.5 Diastrophic dysplasia	0.003	0.997	0.000
Q77.4 Achondroplasia	0.003	0.997	0.000
Q77.3 Chondrodysplasia punctata	0.003	0.997	0.000
Q77.2 Short rib syndrome	0.003	0.997	0.000
Q77.1 Thanatophoric short stature	0.003	0.997	0.000
Q77.0 Achondrogenesis	0.003	0.997	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.003	0.997	0.000
O70.1 Second degree perineal laceration during delivery	0.000	0.997	0.003
S82.30 Fracture of lower end of tibia (closed)	0.003	0.997	0.000
Q65.9 Congenital deformity of hip, unspecified	0.003	0.997	0.000
Q65.6 Unstable hip	0.003	0.997	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.003	0.997	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.003	0.997	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.003	0.997	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.003	0.997	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.003	0.997	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.003	0.997	0.000
Q67.8 Other congenital deformities of chest	0.003	0.997	0.000
Q67.7 Pectus carinatum	0.003	0.997	0.000
Q67.6 Pectus excavatum	0.003	0.997	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.003	0.997	0.000
Q67.3 Plagiocephaly	0.003	0.997	0.000
Q67.2 Dolichocephaly	0.003	0.997	0.000
Q67.1 Compression facies	0.003	0.997	0.000
Q67.0 Facial asymmetry	0.003	0.997	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.003	0.997	0.000
Q54.0 Hypospadias, balanic	0.003	0.997	0.000
S92.3 Fracture of metatarsal bone	0.003	0.997	0.000
G25.0 Essential tremor	0.000	0.997	0.003
Q67.5 Congenital deformity of spine	0.002	0.997	0.000
Q65.8 Other congenital deformities of hip	0.002	0.997	0.000
S92.0 Fracture of calcaneus	0.003	0.997	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.003	0.997	0.000
Q54 Hypospadias	0.003	0.997	0.000
S72.00 Fracture of neck of femur (closed)	0.003	0.997	0.000
M84.0 Malunion of fracture	0.003	0.997	0.000
G25 Other extrapyramidal and movement disorders	0.000	0.997	0.003
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.002	0.997	0.000
E11.3 With ophthalmic complications	0.000	0.997	0.003
M96.0 Pseudarthrosis after fusion or arthrodesis	0.003	0.997	0.000
S92 Fracture of foot, except ankle	0.002	0.997	0.000
Q50-Q56 Congenital malformations of genital organs	0.002	0.997	0.000
S83.2 Tear of meniscus, current	0.000	0.998	0.002
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.000	0.998	0.002
M84.07 Malunion of fracture (Ankle and foot)	0.002	0.998	0.000
S02.50 Fracture of tooth (closed)	0.002	0.998	0.000
S92.1 Fracture of talus	0.002	0.998	0.000
O70.9 Perineal laceration during delivery, unspecified	0.000	0.998	0.002
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.002	0.998	0.000
R77.8 Other specified abnormalities of plasma proteins	0.002	0.998	0.000
M84 Disorders of continuity of bone	0.002	0.998	0.000
M84.04 Malunion of fracture (Hand)	0.002	0.998	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.002	0.998	0.000
S82.10 Fracture of upper end of tibia (closed)	0.002	0.998	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.002	0.998	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.002	0.998	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.002	0.998	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.002	0.998	0.000
R77.1 Abnormality of globulin	0.002	0.998	0.000
M84.03 Malunion of fracture (Forearm)	0.002	0.998	0.000
S92.10 Fracture of talus (closed)	0.002	0.998	0.000
Q54.9 Hypospadias, unspecified	0.002	0.998	0.000
Q55 Other congenital malformations of male genital organs	0.002	0.998	0.000
M84.02 Malunion of fracture (Upper arm)	0.002	0.998	0.000
S92.31 Fracture of metatarsal bone (open)	0.002	0.998	0.000
M84.01 Malunion of fracture (Shoulder region)	0.002	0.998	0.000
S62.61 Fracture of other finger (open)	0.000	0.998	0.002
S92.01 Fracture of calcaneus (open)	0.002	0.998	0.000
Q52 Other congenital malformations of female genitalia	0.002	0.998	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.002	0.998	0.000
Q54.8 Other hypospadias	0.002	0.998	0.000
Q54.4 Congenital chordee	0.002	0.998	0.000
Q54.3 Hypospadias, perineal	0.002	0.998	0.000
Q54.2 Hypospadias, penoscrotal	0.002	0.998	0.000
Q54.1 Hypospadias, penile	0.002	0.998	0.000
S92.5 Fracture of other toe	0.002	0.998	0.000
S40.0 Contusion of shoulder and upper arm	0.002	0.998	0.000
Q53 Undescended testicle	0.002	0.998	0.000
M84.09 Malunion of fracture (Site unspecified)	0.002	0.998	0.000
M84.08 Malunion of fracture (Other)	0.002	0.998	0.000
M84.06 Malunion of fracture (Lower leg)	0.002	0.998	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.002	0.998	0.000
M84.00 Malunion of fracture (Multiple sites)	0.002	0.998	0.000
Q80-Q89 Other congenital malformations	0.002	0.998	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.002	0.998	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.002	0.998	0.000
G25.6 Drug-induced tics and other tics of organic origin	0.000	0.998	0.002
G25.5 Other chorea	0.000	0.998	0.002
G25.4 Drug-induced chorea	0.000	0.998	0.002
G25.2 Other specified forms of tremor	0.000	0.998	0.002
G25.1 Drug-induced tremor	0.000	0.998	0.002
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.002	0.998	0.000
S82.3 Fracture of lower end of tibia	0.002	0.998	0.000
D23.7 Skin of lower limb, including hip	0.002	0.998	0.000
S92.9 Fracture of foot, unspecified	0.002	0.998	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.002	0.998	0.000
Q51 Congenital malformations of uterus and cervix	0.002	0.998	0.000
R77 Other abnormalities of plasma proteins	0.002	0.998	0.000
S92.7 Multiple fractures of foot	0.002	0.998	0.000
Q55.2 Other congenital malformations of testis and scrotum	0.002	0.998	0.000
S92.4 Fracture of great toe	0.002	0.998	0.000
M25.96 Joint disorder, unspecified (Lower leg)	0.002	0.998	0.000
M41 Scoliosis	0.002	0.998	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.000	0.998	0.002
Q85 Phakomatoses, not elsewhere classified	0.002	0.998	0.000
G25.9 Extrapyramidal and movement disorder, unspecified	0.000	0.998	0.002
Z80.9 Family history of malignant neoplasm, unspecified	0.002	0.998	0.000
S92.11 Fracture of talus (open)	0.002	0.998	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.002	0.998	0.000
M84.9 Disorder of continuity of bone, unspecified	0.002	0.998	0.000
M84.8 Other disorders of continuity of bone	0.002	0.998	0.000
M84.3 Stress fracture, not elsewhere classified	0.002	0.998	0.000
M84.2 Delayed union of fracture	0.002	0.998	0.000
Q52.5 Fusion of labia	0.002	0.998	0.000
Q82 Other congenital malformations of skin	0.002	0.998	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.002	0.998	0.000
Q35-Q37 Cleft lip and cleft palate	0.002	0.998	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.002	0.998	0.000
L43.9 Lichen planus, unspecified	0.000	0.998	0.002
S82.1 Fracture of upper end of tibia	0.002	0.998	0.000
S92.2 Fracture of other tarsal bone(s)	0.002	0.998	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.002	0.998	0.000
M84.4 Pathological fracture, not elsewhere classified	0.002	0.998	0.000
S82.00 Fracture of patella (closed)	0.002	0.998	0.000
Z80.8 Family history of malignant neoplasm of other organs or systems	0.002	0.998	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.002	0.998	0.000
Q60-Q64 Congenital malformations of the urinary system	0.002	0.998	0.000
Q55.9 Congenital malformation of male genital organ, unspecified	0.002	0.998	0.000
Q55.8 Other specified congenital malformations of male genital organs	0.002	0.998	0.000
Q55.6 Other congenital malformations of penis	0.002	0.998	0.000
Q55.5 Congenital absence and aplasia of penis	0.002	0.998	0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.002	0.998	0.000
Q55.3 Atresia of vas deferens	0.002	0.998	0.000
Q55.1 Hypoplasia of testis and scrotum	0.002	0.998	0.000
Q55.0 Absence and aplasia of testis	0.002	0.998	0.000
S92.51 Fracture of other toe (open)	0.002	0.998	0.000
Q53.1 Undescended testicle, unilateral	0.002	0.998	0.000
S92.50 Fracture of other toe (closed)	0.002	0.998	0.000
J38.1 Polyp of vocal cord and larynx	0.000	0.998	0.002
Q85.9 Phakomatosis, unspecified	0.002	0.998	0.000
R77.9 Abnormality of plasma protein, unspecified	0.002	0.998	0.000
Q52.9 Congenital malformation of female genitalia, unspecified	0.002	0.998	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.002	0.998	0.000
Q52.7 Other congenital malformations of vulva	0.002	0.998	0.000
Q52.6 Congenital malformation of clitoris	0.002	0.998	0.000
Q52.4 Other congenital malformations of vagina	0.002	0.998	0.000
Q52.3 Imperforate hymen	0.002	0.998	0.000
Q52.2 Congenital rectovaginal fistula	0.002	0.998	0.000
Q52.1 Doubling of vagina	0.002	0.998	0.000
Q52.0 Congenital absence of vagina	0.002	0.998	0.000
Q18 Other congenital malformations of face and neck	0.002	0.998	0.000
Q12 Congenital lens malformations	0.002	0.998	0.000
Q53.9 Undescended testicle, unspecified	0.002	0.998	0.000
Q53.2 Undescended testicle, bilateral	0.002	0.998	0.000
Q53.0 Ectopic testis	0.002	0.998	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.002	0.998	0.000
T18.1 Foreign body in oesophagus	0.000	0.998	0.002
Q17 Other congenital malformations of ear	0.002	0.998	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.002	0.998	0.000
Q15 Other congenital malformations of eye	0.002	0.998	0.000
Q14 Congenital malformations of posterior segment of eye	0.002	0.998	0.000
Q13 Congenital malformations of anterior segment of eye	0.002	0.998	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.002	0.998	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.002	0.998	0.000
Q84 Other congenital malformations of integument	0.002	0.998	0.000
Q81 Epidermolysis bullosa	0.002	0.998	0.000
Q80 Congenital ichthyosis	0.002	0.998	0.000
Q82.8 Other specified congenital malformations of skin	0.002	0.998	0.000
Q83 Congenital malformations of breast	0.002	0.998	0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.002	0.998	0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.002	0.998	0.000
S92.91 Fracture of foot, unspecified (open)	0.002	0.998	0.000
S92.90 Fracture of foot, unspecified (closed)	0.002	0.998	0.000
H57.1 Ocular pain	0.000	0.998	0.002
Q10.0 Congenital ptosis	0.002	0.998	0.000
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.002	0.998	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.002	0.998	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.002	0.998	0.000
Q51.6 Embryonic cyst of cervix	0.002	0.998	0.000
Q51.5 Agenesis and aplasia of cervix	0.002	0.998	0.000
Q51.4 Unicornate uterus	0.002	0.998	0.000
Q51.2 Other doubling of uterus	0.002	0.998	0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.002	0.998	0.000
Q51.0 Agenesis and aplasia of uterus	0.002	0.998	0.000
Q56.4 Indeterminate sex, unspecified	0.002	0.998	0.000
Q56.3 Pseudohermaphroditism, unspecified	0.002	0.998	0.000
Q56.2 Female pseudohermaphroditism, not elsewhere classified	0.002	0.998	0.000
Q56.1 Male pseudohermaphroditism, not elsewhere classified	0.002	0.998	0.000
Q56.0 Hermaphroditism, not elsewhere classified	0.002	0.998	0.000
R77.2 Abnormality of alphafetoprotein	0.002	0.998	0.000
R77.0 Abnormality of albumin	0.002	0.998	0.000
S92.71 Multiple fractures of foot (open)	0.002	0.998	0.000
S92.70 Multiple fractures of foot (closed)	0.002	0.998	0.000
I51.8 Other ill-defined heart diseases	0.002	0.998	0.000
Z01.4 Gynaecological examination (general)(routine)	0.002	0.998	0.000
S92.40 Fracture of great toe (closed)	0.002	0.998	0.000
Q51.3 Bicornate uterus	0.002	0.998	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.002	0.998	0.000
S82.0 Fracture of patella	0.002	0.998	0.000
S82.31 Fracture of lower end of tibia (open)	0.002	0.998	0.000
M41.5 Other secondary scoliosis	0.002	0.998	0.000
M41.4 Neuromuscular scoliosis	0.002	0.998	0.000
M41.3 Thoracogenic scoliosis	0.002	0.998	0.000
M41.2 Other idiopathic scoliosis	0.002	0.998	0.000
M41.1 Juvenile idiopathic scoliosis	0.002	0.998	0.000
M41.0 Infantile idiopathic scoliosis	0.002	0.998	0.000
S83.7 Injury to multiple structures of knee	0.000	0.998	0.002
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.000	0.998	0.002
S83.3 Tear of articular cartilage of knee, current	0.000	0.998	0.002
S83.1 Dislocation of knee	0.000	0.998	0.002
S83.0 Dislocation of patella	0.000	0.998	0.002
S40 Superficial injury of shoulder and upper arm	0.002	0.998	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.002	0.998	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.998	0.002
Q87.4 Marfan's syndrome	0.002	0.998	0.000
Q00-Q07 Congenital malformations of the nervous system	0.001	0.998	0.000
Q85.8 Other phakomatoses, not elsewhere classified	0.001	0.998	0.000
Q85.1 Tuberous sclerosis	0.001	0.998	0.000
Q63 Other congenital malformations of kidney	0.002	0.998	0.000
Z80 Family history of malignant neoplasm	0.002	0.998	0.000
S92.41 Fracture of great toe (open)	0.001	0.998	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.000	0.998	0.002
Q34 Other congenital malformations of respiratory system	0.001	0.998	0.000
Q33 Congenital malformations of lung	0.001	0.998	0.000
Q32 Congenital malformations of trachea and bronchus	0.001	0.998	0.000
Q31 Congenital malformations of larynx	0.001	0.998	0.000
Q30 Congenital malformations of nose	0.001	0.998	0.000
Q37 Cleft palate with cleft lip	0.001	0.998	0.000
Q36 Cleft lip	0.001	0.998	0.000
Q35 Cleft palate	0.001	0.998	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.001	0.998	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.001	0.998	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.001	0.998	0.000
Q96 Turner's syndrome	0.001	0.998	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.001	0.998	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.001	0.998	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.001	0.998	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.001	0.998	0.000
Q90 Down's syndrome	0.001	0.998	0.000
M84.29 Delayed union of fracture (Site unspecified)	0.001	0.998	0.000
M84.28 Delayed union of fracture (Other)	0.001	0.998	0.000
M84.27 Delayed union of fracture (Ankle and foot)	0.001	0.998	0.000
M84.26 Delayed union of fracture (Lower leg)	0.001	0.998	0.000
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.001	0.998	0.000
M84.24 Delayed union of fracture (Hand)	0.001	0.998	0.000
M84.23 Delayed union of fracture (Forearm)	0.001	0.998	0.000
M84.22 Delayed union of fracture (Upper arm)	0.001	0.998	0.000
M84.21 Delayed union of fracture (Shoulder region)	0.001	0.998	0.000
M84.20 Delayed union of fracture (Multiple sites)	0.001	0.998	0.000
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.001	0.998	0.000
M84.38 Stress fracture, not elsewhere classified (Other)	0.001	0.998	0.000
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.001	0.998	0.000
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.001	0.998	0.000
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.001	0.998	0.000
M84.34 Stress fracture, not elsewhere classified (Hand)	0.001	0.998	0.000
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.001	0.998	0.000
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.001	0.998	0.000
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.001	0.998	0.000
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.001	0.998	0.000
M84.89 Other disorders of continuity of bone (Site unspecified)	0.001	0.998	0.000
M84.88 Other disorders of continuity of bone (Other)	0.001	0.998	0.000
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.001	0.998	0.000
M84.86 Other disorders of continuity of bone (Lower leg)	0.001	0.998	0.000
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.001	0.998	0.000
M84.84 Other disorders of continuity of bone (Hand)	0.001	0.998	0.000
M84.83 Other disorders of continuity of bone (Forearm)	0.001	0.998	0.000
M84.82 Other disorders of continuity of bone (Upper arm)	0.001	0.998	0.000
M84.81 Other disorders of continuity of bone (Shoulder region)	0.001	0.998	0.000
M84.80 Other disorders of continuity of bone (Multiple sites)	0.001	0.998	0.000
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.001	0.998	0.000
M84.98 Disorder of continuity of bone, unspecified (Other)	0.001	0.998	0.000
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.001	0.998	0.000
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.001	0.998	0.000
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.001	0.998	0.000
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.001	0.998	0.000
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.001	0.998	0.000
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.001	0.998	0.000
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.001	0.998	0.000
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.001	0.998	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.001	0.998	0.000
E10.3 With ophthalmic complications	0.000	0.998	0.002
M41.8 Other forms of scoliosis	0.001	0.998	0.000
Q82.9 Congenital malformation of skin, unspecified	0.001	0.998	0.000
Q82.5 Congenital nonneoplastic naevus	0.001	0.998	0.000
Q82.4 Ectodermal dysplasia (anhidrotic)	0.001	0.998	0.000
Q82.3 Incontinentia pigmenti	0.001	0.998	0.000
Q82.2 Mastocytosis	0.001	0.998	0.000
Q82.1 Xeroderma pigmentosum	0.001	0.998	0.000
Q82.0 Hereditary lymphoedema	0.001	0.998	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.002	0.998	0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.001	0.998	0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.001	0.998	0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.001	0.998	0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.001	0.998	0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.001	0.998	0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.001	0.998	0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.001	0.998	0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.001	0.998	0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.001	0.998	0.000
S82.11 Fracture of upper end of tibia (open)	0.001	0.998	0.000
H60.9 Otitis externa, unspecified	0.002	0.998	0.000
Q10.7 Congenital malformation of orbit	0.001	0.998	0.000
Q10.6 Other congenital malformations of lachrymal apparatus	0.001	0.998	0.000
Q10.5 Congenital stenosis and stricture of lachrymal duct	0.001	0.998	0.000
Q10.4 Absence and agenesis of lachrymal apparatus	0.001	0.998	0.000
Q10.3 Other congenital malformations of eyelid	0.001	0.998	0.000
Q10.2 Congenital entropion	0.001	0.998	0.000
Q10.1 Congenital ectropion	0.001	0.998	0.000
H36 Retinal disorders in diseases classified elsewhere	0.000	0.998	0.002
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.001	0.998	0.000
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.001	0.998	0.000
Q87.3 Congenital malformation syndromes involving early overgrowth	0.001	0.998	0.000
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.001	0.998	0.000
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.001	0.998	0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.001	0.998	0.000
Q64 Other congenital malformations of urinary system	0.001	0.998	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.001	0.998	0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
S82.21 Fracture of shaft of tibia (open)	0.002	0.998	0.000
Q12.0 Congenital cataract	0.001	0.998	0.000
B07 Viral warts	0.000	0.998	0.002
M84.48 Pathological fracture, not elsewhere classified (Other)	0.001	0.998	0.000
J86.9 Pyothorax without fistula	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations