TreeWAS – Variant ID: rs12600691

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter IX Diseases of the circulatory system	1.000	0.000
Chapter II Neoplasms	1.000	0.000
# Top node	1.000	0.000
I30-I52 Other forms of heart disease	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.998	0.002
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.997	0.003
C15-C26 Malignant neoplasms of digestive organs	0.992	0.008
I42 Cardiomyopathy	0.990	0.010
D37-D48 Neoplasms of uncertain or unknown behaviour	0.990	0.010
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.990	0.010
I50 Heart failure	0.985	0.015
Chapter XX External causes of morbidity and mortality	0.984	0.016
I50.0 Congestive heart failure	0.970	0.030
I51 Complications and ill-defined descriptions of heart disease	0.970	0.030
M80-M85 Disorders of bone density and structure	0.968	0.032
C18 Malignant neoplasm of colon	0.965	0.035
C79 Secondary malignant neoplasm of other sites	0.965	0.035
I70-I79 Diseases of arteries, arterioles and capillaries	0.965	0.035
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.964	0.036
C78.7 Secondary malignant neoplasm of liver	0.959	0.041
Chapter VI Diseases of the nervous system	0.953	0.047
W20-W49 Exposure to inanimate mechanical forces	0.949	0.051
I95-I99 Other and unspecified disorders of the circulatory system	0.948	0.052
I34 Nonrheumatic mitral valve disorders	0.939	0.061
M20-M25 Other joint disorders	0.939	0.061
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.930	0.070
I51.8 Other ill-defined heart diseases	0.927	0.073
M81 Osteoporosis without pathological fracture	0.925	0.075
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.923	0.077
C18.7 Sigmoid colon	0.923	0.077
I95 Hypotension	0.919	0.081
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.915	0.085
I95.1 Orthostatic hypotension	0.910	0.090
I34.0 Mitral (valve) insufficiency	0.908	0.092
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.905	0.095
T15-T19 Effects of foreign body entering through natural orifice	0.905	0.095
M05-M14 Inflammatory polyarthropathies	0.905	0.095
T20-T25 Burns and corrosions of external body surface, specified by site	0.904	0.096
I42.1 Obstructive hypertrophic cardiomyopathy	0.903	0.097
I71 Aortic aneurysm and dissection	0.903	0.097
S60-S69 Injuries to the wrist and hand	0.901	0.099
C79.9 Secondary malignant neoplasm, unspecified site	0.900	0.100
I42.9 Cardiomyopathy, unspecified	0.899	0.101
C78.0 Secondary malignant neoplasm of lung	0.898	0.102
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.895	0.105
M81.9 Osteoporosis, unspecified	0.894	0.106
C19 Malignant neoplasm of rectosigmoid junction	0.894	0.106
C15 Malignant neoplasm of oesophagus	0.893	0.107
S00-S09 Injuries to the head	0.891	0.108
T66-T78 Other and unspecified effects of external causes	0.892	0.108
G90-G99 Other disorders of the nervous system	0.888	0.112
C64-C68 Malignant neoplasms of urinary tract	0.888	0.112
W29 Contact with other powered hand tools and household machinery	0.887	0.113
I42.0 Dilated cardiomyopathy	0.887	0.113
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.887	0.113
I27 Other pulmonary heart diseases	0.883	0.117
Chapter XXI Factors influencing health status and contact with health services	0.880	0.120
M06 Other rheumatoid arthritis	0.873	0.127
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.872	0.128
I30 Acute pericarditis	0.871	0.129
C18.0 Caecum	0.870	0.130
Z40-Z54 Persons encountering health services for specific procedures and health care	0.869	0.131
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.869	0.131
M25 Other joint disorders, not elsewhere classified	0.868	0.132
G70-G73 Diseases of myoneural junction and muscle	0.868	0.132
S50-S59 Injuries to the elbow and forearm	0.868	0.132
Y40 Systemic antibiotics	0.866	0.134
S80-S89 Injuries to the knee and lower leg	0.864	0.136
Z51 Other medical care	0.864	0.136
G40-G47 Episodic and paroxysmal disorders	0.860	0.140
M81.90 Osteoporosis, unspecified (Multiple sites)	0.860	0.140
Z51.1 Chemotherapy session for neoplasm	0.858	0.142
G00-G09 Inflammatory diseases of the central nervous system	0.855	0.145
D48.1 Connective and other soft tissue	0.854	0.146
C64 Malignant neoplasm of kidney, except renal pelvis	0.850	0.150
G95 Other diseases of spinal cord	0.850	0.150
C78.1 Secondary malignant neoplasm of mediastinum	0.847	0.153
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.845	0.155
W29.9 Unspecified place	0.843	0.157
I50.1 Left ventricular failure	0.842	0.158
M86-M90 Other osteopathies	0.838	0.162
M45-M49 Spondylopathies	0.838	0.162
S32 Fracture of lumbar spine and pelvis	0.836	0.164
M06.9 Rheumatoid arthritis, unspecified	0.832	0.168
C16 Malignant neoplasm of stomach	0.832	0.168
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.831	0.169
M24 Other specific joint derangements	0.827	0.173
D00-D09 In situ neoplasms	0.825	0.174
M65-M68 Disorders of synovium and tendon	0.825	0.175
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.824	0.176
C79.8 Secondary malignant neoplasm of other specified sites	0.820	0.180
Y41 Other systemic anti-infectives and antiparasitics	0.818	0.182
I51.9 Heart disease, unspecified	0.815	0.185
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.815	0.185
M25.8 Other specified joint disorders	0.815	0.185
I74 Arterial embolism and thrombosis	0.815	0.185
T79-T79 Certain early complications of trauma	0.814	0.186
Z51.8 Other specified medical care	0.814	0.186
Y57 Other and unspecified drugs and medicaments	0.813	0.187
I46 Cardiac arrest	0.812	0.187
Z43 Attention to artificial openings	0.811	0.189
C92 Myeloid leukaemia	0.811	0.189
T18 Foreign body in alimentary tract	0.811	0.189
S20-S29 Injuries to the thorax	0.807	0.193
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.807	0.193
Y43 Primarily systemic agents	0.806	0.194
I27.0 Primary pulmonary hypertension	0.804	0.196
Q80-Q89 Other congenital malformations	0.804	0.196
S01 Open wound of head	0.803	0.197
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.802	0.198
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.800	0.200
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.799	0.201
I33 Acute and subacute endocarditis	0.798	0.202
W44 Foreign body entering into or through eye or natural orifice	0.797	0.203
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.795	0.205
M84 Disorders of continuity of bone	0.795	0.205
Z53 Persons encountering health services for specifie procedures, not carried out	0.794	0.206
T68 Hypothermia	0.793	0.207
S90-S99 Injuries to the ankle and foot	0.792	0.208
S32.0 Fracture of lumbar vertebra	0.791	0.209
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.791	0.209
M34 Systemic sclerosis	0.790	0.210
I27.2 Other secondary pulmonary hypertension	0.789	0.211
C15.9 Oesophagus, unspecified	0.789	0.211
S06 Intracranial injury	0.788	0.211
M21 Other acquired deformities of limbs	0.785	0.215
V10-V19 Pedal cyclist injured in transport accident	0.784	0.216
D37.1 Stomach	0.784	0.216
S09 Other and unspecified injuries of head	0.784	0.216
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.783	0.217
D47.3 Essential (haemorrhagic) thrombocythaemia	0.781	0.219
S81 Open wound of lower leg	0.781	0.219
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.780	0.219
C90 Multiple myeloma and malignant plasma cell neoplasms	0.780	0.220
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.780	0.220
I45 Other conduction disorders	0.777	0.222
C23 Malignant neoplasm of gallbladder	0.777	0.223
M85 Other disorders of bone density and structure	0.776	0.224
C81 Hodgkin's disease	0.776	0.224
T31 Burns classified according to extent of body surface involved	0.776	0.224
D47.2 Monoclonal gammopathy	0.775	0.225
Y40.0 Penicillins	0.774	0.226
Z53.0 Procedure not carried out because of contraindication	0.773	0.227
T36-T50 Poisoning by drugs, medicaments and biological substances	0.772	0.228
D70-D77 Other diseases of blood and blood-forming organs	0.771	0.229
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.770	0.230
G45 Transient cerebral ischaemic attacks and related syndromes	0.770	0.230
V40-V49 Car occupant injured in transport accident	0.770	0.230
G70 Myasthenia gravis and other myoneural disorders	0.769	0.231
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.768	0.232
I42.2 Other hypertrophic cardiomyopathy	0.768	0.232
S66 Injury of muscle and tendon at wrist and hand level	0.767	0.233
S52 Fracture of forearm	0.767	0.233
T20 Burn and corrosion of head and neck	0.765	0.235
S32.00 Fracture of lumbar vertebra (closed)	0.760	0.240
Y44 Agents primarily affecting blood constituents	0.759	0.241
M50-M54 Other dorsopathies	0.759	0.241
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.758	0.242
I42.6 Alcoholic cardiomyopathy	0.757	0.243
G95.8 Other specified diseases of spinal cord	0.756	0.244
Z51.0 Radiotherapy session	0.754	0.246
C16.0 Cardia	0.753	0.247
X50-X57 Overexertion, travel and privation	0.751	0.249
S01.8 Open wound of other parts of head	0.750	0.250
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.750	0.250
M60-M63 Disorders of muscles	0.750	0.250
I36 Nonrheumatic tricuspid valve disorders	0.749	0.250
M31 Other necrotising vasculopathies	0.749	0.251
M40-M43 Deforming dorsopathies	0.749	0.251
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.746	0.254
C17 Malignant neoplasm of small intestine	0.746	0.254
M25.7 Osteophyte	0.745	0.255
I77 Other disorders of arteries and arterioles	0.744	0.256
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.743	0.257
C51-C58 Malignant neoplasms of female genital organs	0.743	0.257
Z43.3 Attention to colostomy	0.741	0.259
W49 Exposure to other and unspecified inanimate mechanical forces	0.741	0.259
D03 Melanoma in situ	0.740	0.260
M91-M94 Chondropathies	0.738	0.262
M33 Dermatopolymyositis	0.737	0.263
S61 Open wound of wrist and hand	0.737	0.263
G95.1 Vascular myelopathies	0.736	0.264
C18.3 Hepatic flexure	0.736	0.264
T23 Burn and corrosion of wrist and hand	0.734	0.266
G40 Epilepsy	0.733	0.267
M81.98 Osteoporosis, unspecified (Other)	0.733	0.267
Y51 Drugs primarily affecting the autonomic nervous system	0.733	0.267
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.732	0.268
Chapter VII Diseases of the eye and adnexa	0.731	0.269
X40-X49 Accidental poisoning by and exposure to noxious substances	0.729	0.271
X20-X29 Contact with venomous animals and plants	0.729	0.271
C78.2 Secondary malignant neoplasm of pleura	0.729	0.271
W21 Striking against or struck by sports equipment	0.729	0.271
I47 Paroxysmal tachycardia	0.728	0.272
D72 Other disorders of white blood cells	0.728	0.272
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.728	0.272
Z46 Fitting and adjustment of other devices	0.727	0.273
M54 Dorsalgia	0.727	0.273
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.726	0.274
I31 Other diseases of pericardium	0.726	0.274
M46 Other inflammatory spondylopathies	0.724	0.276
S62 Fracture at wrist and hand level	0.724	0.276
M45 Ankylosing spondylitis	0.724	0.276
C18.4 Transverse colon	0.724	0.276
I30.1 Infective pericarditis	0.724	0.276
D47.1 Chronic myeloproliferative disease	0.723	0.277
D37.5 Rectum	0.723	0.277
C15.5 Lower third of oesophagus	0.722	0.278
M65 Synovitis and tenosynovitis	0.722	0.278
C95 Leukaemia of unspecified cell type	0.721	0.279
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.721	0.279
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.720	0.280
Chapter XXII Codes for special purposes	0.720	0.280
T17 Foreign body in respiratory tract	0.719	0.281
G91 Hydrocephalus	0.717	0.283
G01 Meningitis in bacterial diseases classified elsewhere	0.717	0.283
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
I52 Other heart disorders in diseases classified elsewhere	0.717	0.283
I48 Atrial fibrillation and flutter	0.717	0.283
I43 Cardiomyopathy in diseases classified elsewhere	0.717	0.283
I41 Myocarditis in diseases classified elsewhere	0.717	0.283
I40 Acute myocarditis	0.717	0.283
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.717	0.283
I37 Pulmonary valve disorders	0.717	0.283
I32 Pericarditis in diseases classified elsewhere	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.717	0.283
I05-I09 Chronic rheumatic heart diseases	0.717	0.283
I51.7 Cardiomegaly	0.716	0.284
I42.8 Other cardiomyopathies	0.716	0.284
Z40 Prophylactic surgery	0.716	0.284
C76 Malignant neoplasm of other and ill-defined sites	0.716	0.284
G45.9 Transient cerebral ischaemic attack, unspecified	0.716	0.284
I30.9 Acute pericarditis, unspecified	0.716	0.284
W00-W19 Falls	0.715	0.285
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.715	0.285
S01.1 Open wound of eyelid and periocular area	0.715	0.285
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.713	0.287
C18.9 Colon, unspecified	0.712	0.288
M05 Seropositive rheumatoid arthritis	0.711	0.289
D80-D89 Certain disorders involving the immune mechanism	0.711	0.289
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.711	0.289
C21 Malignant neoplasm of anus and anal canal	0.711	0.289
Y43.3 Other antineoplastic drugs	0.711	0.289
M23 Internal derangement of knee	0.710	0.290
I42.7 Cardiomyopathy due to drugs and other external agents	0.710	0.290
I42.5 Other restrictive cardiomyopathy	0.710	0.290
I42.4 Endocardial fibroelastosis	0.710	0.290
I42.3 Endomyocardial (eosinophilic) disease	0.710	0.290
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.710	0.290
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.710	0.290
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.710	0.290
X58-X59 Accidental exposure to other and unspecified factors	0.709	0.291
Z43.0 Attention to tracheostomy	0.709	0.291
T31.0 Burns involving less than 10% of body surface	0.709	0.291
S09.9 Unspecified injury of head	0.707	0.293
G80-G83 Cerebral palsy and other paralytic syndromes	0.706	0.294
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.705	0.295
Y35-Y36 Legal intervention and operations of war	0.705	0.295
Y10-Y34 Event of undetermined intent	0.705	0.295
Y00-Y09 Assault	0.705	0.295
X85-X99 Assault	0.705	0.295
X30-X39 Exposure to forces of nature	0.705	0.295
X10-X19 Contact with heat and hot substances	0.705	0.295
X00-X09 Exposure to smoke, fire and flames	0.705	0.295
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.705	0.295
W75-W84 Other accidental threats to breathing	0.705	0.295
W65-W74 Accidental drowning and submersion	0.705	0.295
W50-W64 Exposure to animate mechanical forces	0.705	0.295
V98-V99 Other and unspecified transport accidents	0.705	0.295
V95-V97 Air and space transport accidents	0.705	0.295
V90-V94 Water transport accidents	0.705	0.295
V70-V79 Bus occupant injured in transport accident	0.705	0.295
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.705	0.295
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.705	0.295
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.705	0.295
V01-V09 Pedestrian injured in transport accident	0.705	0.295
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.705	0.295
I46.0 Cardiac arrest with successful resuscitation	0.704	0.296
C18.5 Splenic flexure	0.703	0.297
D06 Carcinoma in situ of cervix uteri	0.702	0.298
Z51.5 Palliative care	0.702	0.298
S27 Injury of other and unspecified intrathoracic organs	0.701	0.299
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.701	0.299
I82 Other venous embolism and thrombosis	0.700	0.300
C92.1 Chronic myeloid leukaemia	0.700	0.300
Chapter VIII Diseases of the ear and mastoid process	0.700	0.300
S10-S19 Injuries to the neck	0.699	0.301
D48.7 Other specified sites	0.699	0.301
I51.0 Cardiac septal defect, acquired	0.699	0.301
H30-H36 Disorders of choroid and retina	0.699	0.301
T93 Sequelae of injuries of lower limb	0.698	0.302
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.698	0.302
S51 Open wound of forearm	0.698	0.302
G70.0 Myasthenia gravis	0.698	0.302
M25.6 Stiffness of joint, not elsewhere classified	0.697	0.303
I51.6 Cardiovascular disease, unspecified	0.697	0.303
D72.8 Other specified disorders of white blood cells	0.697	0.303
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.697	0.303
Q38-Q45 Other congenital malformations of the digestive system	0.696	0.304
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.696	0.304
I73 Other peripheral vascular diseases	0.696	0.304
D48.0 Bone and articular cartilage	0.696	0.304
I51.5 Myocardial degeneration	0.695	0.305
I51.4 Myocarditis, unspecified	0.695	0.305
I51.3 Intracardiac thrombosis, not elsewhere classified	0.695	0.305
I51.2 Rupture of papillary muscle, not elsewhere classified	0.695	0.305
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.695	0.305
S81.0 Open wound of knee	0.695	0.305
T18.5 Foreign body in anus and rectum	0.695	0.305
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.695	0.305
Z44 Fitting and adjustment of external prosthetic device	0.694	0.306
M83 Adult osteomalacia	0.694	0.306
M82 Osteoporosis in diseases classified elsewhere	0.694	0.306
S64 Injury of nerves at wrist and hand level	0.694	0.306
G96 Other disorders of central nervous system	0.692	0.308
C18.8 Overlapping lesion of colon	0.692	0.308
C66 Malignant neoplasm of ureter	0.692	0.308
T78 Adverse effects, not elsewhere classified	0.692	0.308
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.692	0.308
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.692	0.308
Y59 Other and unspecified vaccines and biological substances	0.691	0.309
Y58 Bacterial vaccines	0.691	0.309
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.691	0.309
Y53 Agents primarily affecting the gastro-intestinal system	0.691	0.309
Y50 Central nervous system stimulants, not elsewhere classified	0.691	0.309
Y49 Psychotropic drugs, not elsewhere classified	0.691	0.309
Y48 Anaesthetics and therapeutic gases	0.691	0.309
Y47 Sedatives, hypnotics and antianxiety drugs	0.691	0.309
Y46 Antiepileptics and anti-Parkinsonism drugs	0.691	0.309
Y40.9 Systemic antibiotic, unspecified	0.690	0.310
C78.4 Secondary malignant neoplasm of small intestine	0.689	0.310
W44.0 Home	0.689	0.311
X60-X84 Intentional self-harm	0.688	0.312
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.687	0.313
Y57.9 Drug or medicament, unspecified	0.687	0.313
M86 Osteomyelitis	0.685	0.314
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.685	0.315
M24.5 Contracture of joint	0.684	0.316
W22 Striking against or struck by other objects	0.683	0.316
M00-M03 Infectious arthropathies	0.683	0.317
M24.2 Disorder of ligament	0.682	0.318
G72 Other myopathies	0.681	0.318
T79 Certain early complications of trauma, not elsewhere classified	0.681	0.318
S31 Open wound of abdomen, lower back and pelvis	0.681	0.319
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.681	0.319
C79.6 Secondary malignant neoplasm of ovary	0.680	0.319
W46 Contact with hypodermic needle	0.680	0.320
W45 Foreign body or object entering through skin	0.680	0.320
W43 Exposure to vibration	0.680	0.320
W42 Exposure to noise	0.680	0.320
W41 Exposure to high-pressure jet	0.680	0.320
W40 Explosion of other materials	0.680	0.320
W39 Discharge of firework	0.680	0.320
W38 Explosion and rupture of other specified pressurised devices	0.680	0.320
W37 Explosion and rupture of pressurised tyre, pipe or hose	0.680	0.320
W36 Explosion and rupture of gas cylinder	0.680	0.320
W35 Explosion and rupture of boiler	0.680	0.320
W34 Discharge from other and unspecified firearms	0.680	0.320
W33 Rifle, shotgun and larger firearm discharge	0.680	0.320
W32 Handgun discharge	0.680	0.320
W31 Contact with other and unspecified machinery	0.680	0.320
W30 Contact with agricultural machinery	0.680	0.320
W28 Contact with powered lawn mower	0.680	0.320
W27 Contact with nonpowered hand tool	0.680	0.320
W26 Contact with knife, sword or dagger	0.680	0.320
W24 Contact with lifting and transmission devices, not elsewhere classified	0.680	0.320
W23 Caught, crushed, jammed or pinched in or between objects	0.680	0.320
W20 Struck by thrown, projected or falling object	0.680	0.320
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.679	0.321
V20-V29 Motorcycle rider injured in transport accident	0.679	0.321
C79.7 Secondary malignant neoplasm of adrenal gland	0.679	0.321
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.678	0.322
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.678	0.322
M84.1 Nonunion of fracture [pseudarthrosis]	0.678	0.322
I70 Atherosclerosis	0.677	0.323
M06.3 Rheumatoid nodule	0.676	0.324
D44.3 Pituitary gland	0.676	0.324
S52.8 Fracture of other parts of forearm	0.675	0.325
C90.0 Multiple myeloma	0.675	0.325
M06.0 Seronegative rheumatoid arthritis	0.675	0.325
Q60-Q64 Congenital malformations of the urinary system	0.674	0.326
I34.8 Other nonrheumatic mitral valve disorders	0.674	0.326
I34.2 Nonrheumatic mitral (valve) stenosis	0.674	0.326
C80 Malignant neoplasm without specification of site	0.674	0.326
D46 Myelodysplastic syndromes	0.674	0.326
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.673	0.327
M32 Systemic lupus erythematosus	0.673	0.327
M30 Polyarteritis nodosa and related conditions	0.673	0.327
I98 Other disorders of circulatory system in diseases classified elsewhere	0.673	0.327
G95.0 Syringomyelia and syringobulbia	0.673	0.327
T91 Sequelae of injuries of neck and trunk	0.672	0.328
C50-C50 Malignant neoplasm of breast	0.671	0.329
M80 Osteoporosis with pathological fracture	0.670	0.330
G71 Primary disorders of muscles	0.668	0.332
M25.9 Joint disorder, unspecified	0.668	0.332
M81.4 Drug-induced osteoporosis	0.668	0.332
S61.9 Open wound of wrist and hand, part unspecified	0.667	0.333
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.667	0.333
C94 Other leukaemias of specified cell type	0.667	0.333
C93 Monocytic leukaemia	0.667	0.333
C88 Malignant immunoproliferative diseases	0.667	0.333
C86 Other specified types of T/NK-cell lymphoma	0.667	0.333
C84 Peripheral and cutaneous T-cell lymphomas	0.667	0.333
M25.86 Other specified joint disorders (Lower leg)	0.667	0.333
D38.1 Trachea, bronchus and lung	0.666	0.334
T18.9 Foreign body in alimentary tract, part unspecified	0.666	0.334
G95.9 Disease of spinal cord, unspecified	0.666	0.334
C81.9 Hodgkin's disease, unspecified	0.665	0.335
S32.7 Multiple fractures of lumbar spine and pelvis	0.665	0.335
M25.83 Other specified joint disorders (Forearm)	0.665	0.335
M89 Other disorders of bone	0.664	0.336
S05 Injury of eye and orbit	0.664	0.336
M25.74 Osteophyte (Hand)	0.663	0.336
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.663	0.337
M81.8 Other osteoporosis	0.663	0.337
M81.6 Localised osteoporosis [Lequesne]	0.663	0.337
M81.5 Idiopathic osteoporosis	0.663	0.337
M81.3 Postsurgical malabsorption osteoporosis	0.663	0.337
M81.2 Osteoporosis of disuse	0.663	0.337
M81.1 Postoophorectomy osteoporosis	0.663	0.337
M81.0 Postmenopausal osteoporosis	0.663	0.337
I44 Atrioventricular and left bundle-branch block	0.663	0.337
H34 Retinal vascular occlusions	0.663	0.337
V80-V89 Other land transport accidents	0.662	0.338
I28 Other diseases of pulmonary vessels	0.662	0.338
M06.4 Inflammatory polyarthropathy	0.661	0.339
C18.1 Appendix	0.660	0.340
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.660	0.340
S83.2 Tear of meniscus, current	0.660	0.340
I95.8 Other hypotension	0.659	0.341
I95.0 Idiopathic hypotension	0.659	0.341
S81.9 Open wound of lower leg, part unspecified	0.659	0.341
I38 Endocarditis, valve unspecified	0.658	0.342
S68 Traumatic amputation of wrist and hand	0.658	0.342
S06.6 Traumatic subarachnoid haemorrhage	0.658	0.342
C18.6 Descending colon	0.657	0.343
M34.8 Other forms of systemic sclerosis	0.657	0.343
G04 Encephalitis, myelitis and encephalomyelitis	0.656	0.343
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.656	0.344
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.656	0.344
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.656	0.344
D47.4 Osteomyelofibrosis	0.656	0.344
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.656	0.344
Y52 Agents primarily affecting the cardiovascular system	0.655	0.344
C49 Malignant neoplasm of other connective and soft tissue	0.655	0.345
C02 Malignant neoplasm of other and unspecified parts of tongue	0.654	0.346
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.654	0.346
M54.5 Low back pain	0.654	0.346
G41 Status epilepticus	0.654	0.346
M25.87 Other specified joint disorders (Ankle and foot)	0.653	0.347
I33.0 Acute and subacute infective endocarditis	0.653	0.347
S60 Superficial injury of wrist and hand	0.653	0.347
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons	0.653	0.347
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.653	0.347
I78 Diseases of capillaries	0.652	0.348
G06 Intracranial and intraspinal abscess and granuloma	0.651	0.349
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.651	0.349
Z43.1 Attention to gastrostomy	0.649	0.351
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.649	0.351
D48.4 Peritoneum	0.649	0.351
D48.3 Retroperitoneum	0.649	0.351
D48.2 Peripheral nerves and autonomic nervous system	0.649	0.351
T19 Foreign body in genito-urinary tract	0.649	0.351
T15 Foreign body on external eye	0.649	0.351
T16 Foreign body in ear	0.649	0.351
D39.1 Ovary	0.649	0.351
M14 Arthropathies in other diseases classified elsewhere	0.648	0.351
M12 Other specific arthropathies	0.648	0.351
M09 Juvenile arthritis in diseases classified elsewhere	0.648	0.351
M08 Juvenile arthritis	0.648	0.351
T25 Burn and corrosion of ankle and foot	0.648	0.352
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.648	0.352
T21 Burn and corrosion of trunk	0.648	0.352
C26 Malignant neoplasm of other and ill-defined digestive organs	0.648	0.352
T14 Injury of unspecified body region	0.648	0.352
C45 Mesothelioma	0.647	0.352
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.647	0.352
I71.8 Aortic aneurysm of unspecified site, ruptured	0.647	0.353
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.647	0.353
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.647	0.353
I71.3 Abdominal aortic aneurysm, ruptured	0.647	0.353
I71.1 Thoracic aortic aneurysm, ruptured	0.647	0.353
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.647	0.353
S65 Injury of blood vessels at wrist and hand level	0.646	0.354
Z43.8 Attention to other artificial openings	0.646	0.354
S06.5 Traumatic subdural haemorrhage	0.645	0.355
M66 Spontaneous rupture of synovium and tendon	0.645	0.355
I74.8 Embolism and thrombosis of other arteries	0.644	0.356
I72 Other aneurysm	0.644	0.356
H34.8 Other retinal vascular occlusions	0.644	0.356
T20.1 Burn of first degree of head and neck	0.644	0.356
S92 Fracture of foot, except ankle	0.643	0.357
M46.9 Inflammatory spondylopathy, unspecified	0.643	0.357
I45.9 Conduction disorder, unspecified	0.642	0.358

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations