TreeWAS – Variant ID: rs12638075

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25.2 Old myocardial infarction	0.000	0.969	0.031
I25 Chronic ischaemic heart disease	0.000	0.974	0.026
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.977	0.023
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.977	0.023
I20-I25 Ischaemic heart diseases	0.000	0.979	0.021
I24 Other acute ischaemic heart diseases	0.000	0.981	0.019
I25.6 Silent myocardial ischaemia	0.000	0.981	0.019
I25.4 Coronary artery aneurysm	0.000	0.981	0.019
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.981	0.019
I25.5 Ischaemic cardiomyopathy	0.000	0.982	0.018
I21 Acute myocardial infarction	0.000	0.982	0.018
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.982	0.018
I25.3 Aneurysm of heart	0.000	0.982	0.018
I24.8 Other forms of acute ischaemic heart disease	0.000	0.982	0.018
R00.1 Bradycardia, unspecified	0.000	0.983	0.017
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.984	0.016
I21.9 Acute myocardial infarction, unspecified	0.000	0.984	0.016
I22 Subsequent myocardial infarction	0.000	0.985	0.015
I23 Certain current complications following acute myocardial infarction	0.000	0.985	0.015
I24.1 Dressler's syndrome	0.000	0.986	0.014
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.986	0.014
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.987	0.013
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.987	0.013
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.987	0.013
I20 Angina pectoris	0.000	0.988	0.012
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.989	0.011
I22.8 Subsequent myocardial infarction of other sites	0.000	0.989	0.011
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.989	0.011
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.989	0.011
I23.8 Other current complications following acute myocardial infarction	0.000	0.989	0.011
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.989	0.011
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.989	0.011
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.989	0.011
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.989	0.011
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.989	0.011
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.989	0.011
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.989	0.011
R00 Abnormalities of heart beat	0.000	0.989	0.011
R00.2 Palpitations	0.000	0.989	0.011
I20.8 Other forms of angina pectoris	0.000	0.990	0.009
I20.1 Angina pectoris with documented spasm	0.000	0.991	0.009
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.991	0.008
R00.8 Other and unspecified abnormalities of heart beat	0.000	0.992	0.008
I25.1 Atherosclerotic heart disease	0.000	0.992	0.008
I21.4 Acute subendocardial myocardial infarction	0.000	0.993	0.007
I20.9 Angina pectoris, unspecified	0.000	0.993	0.007
I20.0 Unstable angina	0.000	0.993	0.007
R04.0 Epistaxis	0.000	0.994	0.006
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.994	0.006
R00.0 Tachycardia, unspecified	0.000	0.995	0.005
R04 Haemorrhage from respiratory passages	0.000	0.995	0.005
Z13.9 Special screening examination, unspecified	0.000	0.996	0.004
I64 Stroke, not specified as haemorrhage or infarction	0.000	0.996	0.004
Z13 Special screening examination for other diseases and disorders	0.000	0.996	0.004
I63.9 Cerebral infarction, unspecified	0.000	0.996	0.004
R04.2 Haemoptysis	0.000	0.996	0.004
R04.9 Haemorrhage from respiratory passages, unspecified	0.000	0.996	0.003
R04.8 Haemorrhage from other sites in respiratory passages	0.000	0.996	0.003
R04.1 Haemorrhage from throat	0.000	0.996	0.003
I60-I69 Cerebrovascular diseases	0.000	0.997	0.003
Z08.0 Follow-up examination after surgery for malignant neoplasm	0.000	0.997	0.003
I63 Cerebral infarction	0.000	0.997	0.003
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.000	0.997	0.003
Z13.8 Special screening examination for other specified diseases and disorders	0.000	0.997	0.003
Z13.7 Special screening examination for congenital malformations, deformations and chromosomal abnormalities	0.000	0.997	0.003
Z13.5 Special screening examination for eye and ear disorders	0.000	0.997	0.003
Z13.4 Special screening examination for certain developmental disorders in childhood	0.000	0.997	0.003
Z13.3 Special screening examination for mental and behavioural disorders	0.000	0.997	0.003
Z13.2 Special screening examination for nutritional disorders	0.000	0.997	0.003
I67 Other cerebrovascular diseases	0.000	0.997	0.003
I62 Other nontraumatic intracranial haemorrhage	0.000	0.997	0.003
I67.9 Cerebrovascular disease, unspecified	0.000	0.997	0.003
Chapter IX Diseases of the circulatory system	0.000	0.997	0.003
H43.8 Other disorders of vitreous body	0.003	0.997	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.000	0.997	0.003
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.000	0.997	0.003
E80.4 Gilbert's syndrome	0.003	0.997	0.000
C43.7 Malignant melanoma of lower limb, including hip	0.003	0.997	0.000
I69 Sequelae of cerebrovascular disease	0.000	0.997	0.003
I61 Intracerebral haemorrhage	0.000	0.997	0.003
Z08 Follow-up examination after treatment for malignant neoplasm	0.000	0.997	0.003
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.000	0.997	0.002
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.000	0.997	0.002
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.000	0.997	0.002
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.000	0.997	0.002
Z13.1 Special screening examination for diabetes mellitus	0.000	0.997	0.002
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.997	0.002
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.000	0.997	0.003
I67.8 Other specified cerebrovascular diseases	0.000	0.997	0.002
I63.8 Other cerebral infarction	0.000	0.997	0.002
R07 Pain in throat and chest	0.000	0.997	0.003
R02 Gangrene, not elsewhere classified	0.000	0.997	0.002
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.000	0.997	0.002
K76.9 Liver disease, unspecified	0.000	0.997	0.002
Z13.83 Encounter for screening for respiratory disorder NEC	0.000	0.997	0.002
Z13.82 Encounter for screening for musculoskeletal disorder	0.000	0.997	0.002
I67.7 Cerebral arteritis, not elsewhere classified	0.000	0.997	0.002
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.000	0.997	0.002
I67.5 Moyamoya disease	0.000	0.997	0.002
I67.4 Hypertensive encephalopathy	0.000	0.997	0.002
I67.3 Progressive vascular leukoencephalopathy	0.000	0.997	0.002
I67.2 Cerebral atherosclerosis	0.000	0.997	0.002
I67.0 Dissection of cerebral arteries, nonruptured	0.000	0.997	0.002
Z12.1 Special screening examination for neoplasm of intestinal tract	0.000	0.997	0.002
Z09.2 Follow-up examination after chemotherapy for other conditions	0.000	0.998	0.002
Z48.8 Other specified surgical follow-up care	0.002	0.998	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.000	0.998	0.002
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.000	0.998	0.002
I62.1 Nontraumatic extradural haemorrhage	0.000	0.998	0.002
I60 Subarachnoid haemorrhage	0.000	0.998	0.002
I67.1 Cerebral aneurysm, nonruptured	0.000	0.998	0.002
I61.9 Intracerebral haemorrhage, unspecified	0.000	0.998	0.002
M54.22 Cervicalgia (Cervical region)	0.000	0.998	0.002
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.000	0.998	0.002
I95-I99 Other and unspecified disorders of the circulatory system	0.000	0.998	0.002
I00-I02 Acute rheumatic fever	0.000	0.998	0.002
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.000	0.998	0.002
I66.8 Occlusion and stenosis of other cerebral artery	0.000	0.998	0.002
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.000	0.998	0.002
I66.3 Occlusion and stenosis of cerebellar arteries	0.000	0.998	0.002
I66.2 Occlusion and stenosis of posterior cerebral artery	0.000	0.998	0.002
I66.1 Occlusion and stenosis of anterior cerebral artery	0.000	0.998	0.002
I66.0 Occlusion and stenosis of middle cerebral artery	0.000	0.998	0.002
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.000	0.998	0.002
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.000	0.998	0.002
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
I68.0 Cerebral amyloid angiopathy	0.000	0.998	0.002
Z08.7 Follow-up examination after combined treatment for malignant neoplasm	0.000	0.998	0.002
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.998	0.002
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.998	0.002
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.998	0.002
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.998	0.002
I61.8 Other intracerebral haemorrhage	0.000	0.998	0.002
I61.6 Intracerebral haemorrhage, multiple localised	0.000	0.998	0.002
I61.5 Intracerebral haemorrhage, intraventricular	0.000	0.998	0.002
I61.4 Intracerebral haemorrhage in cerebellum	0.000	0.998	0.002
I61.3 Intracerebral haemorrhage in brain stem	0.000	0.998	0.002
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.000	0.998	0.002
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.000	0.998	0.002
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm	0.000	0.998	0.002
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.998	0.002
Z13.6 Special screening examination for cardiovascular disorders	0.000	0.998	0.002
I69.3 Sequelae of cerebral infarction	0.000	0.998	0.002
K76.0 Fatty (change of) liver, not elsewhere classified	0.000	0.998	0.002
R07.0 Pain in throat	0.000	0.998	0.002
Z12 Special screening examination for neoplasms	0.000	0.998	0.002
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.998	0.002
R07.2 Precordial pain	0.000	0.998	0.002
R07.4 Chest pain, unspecified	0.000	0.998	0.002
R07.1 Chest pain on breathing	0.000	0.998	0.002
K76 Other diseases of liver	0.000	0.998	0.002
R03 Abnormal blood-pressure reading, without diagnosis	0.000	0.998	0.002
I34.0 Mitral (valve) insufficiency	0.000	0.998	0.002
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.000	0.998	0.002
I34 Nonrheumatic mitral valve disorders	0.000	0.998	0.002
I98 Other disorders of circulatory system in diseases classified elsewhere	0.000	0.998	0.002
I73.9 Peripheral vascular disease, unspecified	0.000	0.998	0.002
R01 Cardiac murmurs and other cardiac sounds	0.000	0.998	0.002
Z04.9 Examination and observation for unspecified reason	0.000	0.998	0.002
Z95.2 Presence of prosthetic heart valve	0.000	0.998	0.002
H43.1 Vitreous haemorrhage	0.002	0.998	0.000
I60.8 Other subarachnoid haemorrhage	0.000	0.998	0.002
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.000	0.998	0.002
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.000	0.998	0.002
I60.5 Subarachnoid haemorrhage from vertebral artery	0.000	0.998	0.002
I60.4 Subarachnoid haemorrhage from basilar artery	0.000	0.998	0.002
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.000	0.998	0.002
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.000	0.998	0.002
H43 Disorders of vitreous body	0.002	0.998	0.000
I34.1 Mitral (valve) prolapse	0.000	0.998	0.002
Z04 Examination and observation for other reasons	0.000	0.998	0.002
Z00-Z13 Persons encountering health services for examination and investigation	0.000	0.998	0.002
Z95.8 Presence of other cardiac and vascular implants and grafts	0.000	0.998	0.002
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.998	0.002
T90.2 Sequelae of fracture of skull and facial bones	0.002	0.998	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.000	0.998	0.002
I65.8 Occlusion and stenosis of other precerebral artery	0.000	0.998	0.002
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.000	0.998	0.002
I65.1 Occlusion and stenosis of basilar artery	0.000	0.998	0.002
I65.0 Occlusion and stenosis of vertebral artery	0.000	0.998	0.002
I02 Rheumatic chorea	0.000	0.998	0.002
I01 Rheumatic fever with heart involvement	0.000	0.998	0.002
I00 Rheumatic fever without mention of heart involvement	0.000	0.998	0.002
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.998	0.002
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.000	0.998	0.002
I98.2 Oesophageal varices in diseases classified elsewhere	0.000	0.998	0.002
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.998	0.002
I95.1 Orthostatic hypotension	0.000	0.998	0.002
K76.8 Other specified diseases of liver	0.000	0.998	0.002
Z95 Presence of cardiac and vascular implants and grafts	0.000	0.998	0.002
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.998	0.002
I30-I52 Other forms of heart disease	0.000	0.998	0.002
I49.9 Cardiac arrhythmia, unspecified	0.000	0.998	0.002
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm	0.000	0.998	0.002
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.000	0.998	0.002
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.000	0.998	0.002
I38 Endocarditis, valve unspecified	0.000	0.998	0.002
Z12.9 Special screening examination for neoplasm, unspecified	0.000	0.998	0.002
Z12.8 Special screening examination for neoplasm of other sites	0.000	0.998	0.002
Z12.6 Special screening examination for neoplasm of bladder	0.000	0.998	0.002
Z12.4 Special screening examination for neoplasm of cervix	0.000	0.998	0.002
Z12.3 Special screening examination for neoplasm of breast	0.000	0.998	0.002
Z12.2 Special screening examination for neoplasm of respiratory organs	0.000	0.998	0.002
Z12.0 Special screening examination for neoplasm of stomach	0.000	0.998	0.002
I95 Hypotension	0.000	0.998	0.002
K76.6 Portal hypertension	0.000	0.998	0.002
I99 Other and unspecified disorders of circulatory system	0.000	0.998	0.002
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.000	0.998	0.002
I05-I09 Chronic rheumatic heart diseases	0.000	0.998	0.002
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.998	0.002
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.000	0.998	0.002
I34.8 Other nonrheumatic mitral valve disorders	0.000	0.998	0.002
I34.2 Nonrheumatic mitral (valve) stenosis	0.000	0.998	0.002
K76.7 Hepatorenal syndrome	0.000	0.998	0.002
K76.5 Hepatic veno-occlusive disease	0.000	0.998	0.002
K76.4 Peliosis hepatis	0.000	0.998	0.002
K76.3 Infarction of liver	0.000	0.998	0.002
K76.2 Central haemorrhagic necrosis of liver	0.000	0.998	0.002
K76.1 Chronic passive congestion of liver	0.000	0.998	0.002
Z04.8 Examination and observation for other specified reasons	0.000	0.998	0.002
S12.10 Fracture of second cervical vertebra (closed)	0.002	0.998	0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.000	0.998	0.002
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.000	0.998	0.002
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.000	0.998	0.002
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
I98.0 Cardiovascular syphilis	0.000	0.998	0.002
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.000	0.998	0.002
R01.2 Other cardiac sounds	0.000	0.998	0.001
R01.0 Benign and innocent cardiac murmurs	0.000	0.998	0.001
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension	0.000	0.998	0.002
Z95.4 Presence of other heart-valve replacement	0.000	0.998	0.002
R39.8 Other and unspecified symptoms and signs involving the urinary system	0.002	0.998	0.000
Z95.0 Presence of cardiac pacemaker	0.000	0.998	0.002
H43.9 Disorder of vitreous body, unspecified	0.002	0.998	0.000
H43.2 Crystalline deposits in vitreous body	0.002	0.998	0.000
H43.0 Vitreous prolapse	0.002	0.998	0.000
Z04.6 General psychiatric examination, requested by authority	0.000	0.998	0.002
Z04.5 Examination and observation following other inflicted injury	0.000	0.998	0.002
Z04.4 Examination and observation following alleged rape and seduction	0.000	0.998	0.002
Z04.2 Examination and observation following work accident	0.000	0.998	0.002
Z04.0 Blood-alcohol and blood-drug test	0.000	0.998	0.002
Z95.1 Presence of aortocoronary bypass graft	0.000	0.998	0.002
I73 Other peripheral vascular diseases	0.000	0.998	0.002
Z04.3 Examination and observation following other accident	0.000	0.998	0.002
Z10 Routine general health check-up of defined subpopulation	0.000	0.998	0.002
Z12.5 Special screening examination for neoplasm of prostate	0.000	0.998	0.001
R06 Abnormalities of breathing	0.000	0.998	0.002
I97.9 Postprocedural disorder of circulatory system, unspecified	0.000	0.998	0.001
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.998	0.001
I97.2 Postmastectomy lymphoedema syndrome	0.000	0.998	0.001
I97.1 Other functional disturbances following cardiac surgery	0.000	0.998	0.001
I97.0 Postcardiotomy syndrome	0.000	0.998	0.001
R07.3 Other chest pain	0.000	0.998	0.002
Y86 Sequelae of other accidents	0.002	0.998	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.000	0.998	0.001
I01.8 Other acute rheumatic heart disease	0.000	0.998	0.001
I01.2 Acute rheumatic myocarditis	0.000	0.998	0.001
I01.1 Acute rheumatic endocarditis	0.000	0.998	0.001
I01.0 Acute rheumatic pericarditis	0.000	0.998	0.001
I02.9 Rheumatic chorea without heart involvement	0.000	0.998	0.001
I02.0 Rheumatic chorea with heart involvement	0.000	0.998	0.001
I83.1 Varicose veins of lower extremities with inflammation	0.002	0.998	0.000
C43 Malignant melanoma of skin	0.002	0.998	0.000
T90 Sequelae of injuries of head	0.002	0.998	0.000
I44.1 Atrioventricular block, second degree	0.000	0.998	0.002
I52 Other heart disorders in diseases classified elsewhere	0.000	0.998	0.001
I49 Other cardiac arrhythmias	0.000	0.998	0.002
I48 Atrial fibrillation and flutter	0.000	0.998	0.001
I43 Cardiomyopathy in diseases classified elsewhere	0.000	0.998	0.001
I41 Myocarditis in diseases classified elsewhere	0.000	0.998	0.001
I40 Acute myocarditis	0.000	0.998	0.001
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.000	0.998	0.001
I37 Pulmonary valve disorders	0.000	0.998	0.001
I36 Nonrheumatic tricuspid valve disorders	0.000	0.998	0.001
I33 Acute and subacute endocarditis	0.000	0.998	0.001
I32 Pericarditis in diseases classified elsewhere	0.000	0.998	0.001
I77 Other disorders of arteries and arterioles	0.000	0.998	0.002
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms	0.000	0.998	0.002
I51.9 Heart disease, unspecified	0.000	0.998	0.002
I51 Complications and ill-defined descriptions of heart disease	0.000	0.998	0.002
I44 Atrioventricular and left bundle-branch block	0.000	0.998	0.002
I31 Other diseases of pericardium	0.000	0.998	0.002
C43.6 Malignant melanoma of upper limb, including shoulder	0.002	0.998	0.000
I95.8 Other hypotension	0.000	0.998	0.001
I95.2 Hypotension due to drugs	0.000	0.998	0.001
I95.0 Idiopathic hypotension	0.000	0.998	0.001
Z04.1 Examination and observation following transport accident	0.000	0.998	0.001
R09.0 Asphyxia	0.000	0.998	0.001
I09 Other rheumatic heart diseases	0.000	0.998	0.001
I06 Rheumatic aortic valve diseases	0.000	0.998	0.001
I05 Rheumatic mitral valve diseases	0.000	0.998	0.001
I28 Other diseases of pulmonary vessels	0.000	0.998	0.001
M43.17 Spondylolisthesis (Lumbosacral region)	0.001	0.998	0.000
S52.60 Fracture of lower end of both ulna and radius (closed)	0.000	0.998	0.001
G47.3 Sleep apnoea	0.000	0.998	0.002
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.998	0.001
I72 Other aneurysm	0.000	0.998	0.001
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.000	0.998	0.001
I77.1 Stricture of artery	0.000	0.998	0.001
I70 Atherosclerosis	0.000	0.998	0.001
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.000	0.998	0.001
C43.3 Malignant melanoma of other and unspecified parts of face	0.001	0.998	0.000
I73.8 Other specified peripheral vascular diseases	0.000	0.998	0.001
I73.1 Thromboangiitis obliterans [Buerger]	0.000	0.998	0.001
R09.3 Abnormal sputum	0.000	0.998	0.001
Z10.8 Routine general health check-up of other defined subpopulations	0.000	0.998	0.001
Z10.3 Routine general health check-up of sports teams	0.000	0.998	0.001
Z10.2 Routine general health check-up of armed forces	0.000	0.998	0.001
Z10.1 Routine general health check-up of inhabitants of institutions	0.000	0.998	0.001
Z10.0 Occupational health examination	0.000	0.998	0.001
I27 Other pulmonary heart diseases	0.000	0.998	0.001
H43.3 Other vitreous opacities	0.001	0.999	0.000
R06.7 Sneezing	0.000	0.999	0.001
R06.6 Hiccough	0.000	0.999	0.001
R06.3 Periodic breathing	0.000	0.999	0.001
R06.1 Stridor	0.000	0.999	0.001
T93.2 Sequelae of other fractures of lower limb	0.001	0.999	0.000
W22.9 Unspecified place	0.001	0.999	0.000
I46 Cardiac arrest	0.000	0.999	0.001
I30 Acute pericarditis	0.000	0.999	0.001
I78 Diseases of capillaries	0.000	0.999	0.001
I31.9 Disease of pericardium, unspecified	0.000	0.999	0.001
T90.9 Sequelae of unspecified injury of head	0.001	0.999	0.000
I07 Rheumatic tricuspid valve diseases	0.000	0.999	0.001
C43.9 Malignant melanoma of skin, unspecified	0.001	0.999	0.000
C43.8 Overlapping malignant melanoma of skin	0.001	0.999	0.000
C43.4 Malignant melanoma of scalp and neck	0.001	0.999	0.000
C43.2 Malignant melanoma of ear and external auricular canal	0.001	0.999	0.000
C43.1 Malignant melanoma of eyelid, including canthus	0.001	0.999	0.000
C43.0 Malignant melanoma of lip	0.001	0.999	0.000
F10.1 Harmful use	0.000	0.999	0.001
I49.5 Sick sinus syndrome	0.000	0.999	0.001
S12.1 Fracture of second cervical vertebra	0.001	0.999	0.000
T90.8 Sequelae of other specified injuries of head	0.001	0.999	0.000
T90.5 Sequelae of intracranial injury	0.001	0.999	0.000
T90.4 Sequelae of injury of eye and orbit	0.001	0.999	0.000
T90.3 Sequelae of injury of cranial nerves	0.001	0.999	0.000
T90.1 Sequelae of open wound of head	0.001	0.999	0.000
T90.0 Sequelae of superficial injury of head	0.001	0.999	0.000
Z01.8 Other specified special examinations	0.000	0.999	0.001
H44.2 Degenerative myopia	0.001	0.999	0.000
I32.8 Pericarditis in other diseases classified elsewhere	0.000	0.999	0.001
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.999	0.001
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.000	0.999	0.001
I33.9 Acute endocarditis, unspecified	0.000	0.999	0.001
I33.0 Acute and subacute infective endocarditis	0.000	0.999	0.001
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.000	0.999	0.001
I36.8 Other nonrheumatic tricuspid valve disorders	0.000	0.999	0.001
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.000	0.999	0.001
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.000	0.999	0.001
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.000	0.999	0.001
I37.9 Pulmonary valve disorder, unspecified	0.000	0.999	0.001
I37.8 Other pulmonary valve disorders	0.000	0.999	0.001
I37.2 Pulmonary valve stenosis with insufficiency	0.000	0.999	0.001
I37.1 Pulmonary valve insufficiency	0.000	0.999	0.001
I37.0 Pulmonary valve stenosis	0.000	0.999	0.001
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.000	0.999	0.001
I39.4 Multiple valve disorders in diseases classified elsewhere	0.000	0.999	0.001
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.000	0.999	0.001
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.000	0.999	0.001
I39.1 Aortic valve disorders in diseases classified elsewhere	0.000	0.999	0.001
I39.0 Mitral valve disorders in diseases classified elsewhere	0.000	0.999	0.001
I40.9 Acute myocarditis, unspecified	0.000	0.999	0.001
I40.8 Other acute myocarditis	0.000	0.999	0.001
I40.1 Isolated myocarditis	0.000	0.999	0.001
I40.0 Infective myocarditis	0.000	0.999	0.001
I41.8 Myocarditis in other diseases classified elsewhere	0.000	0.999	0.001
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.999	0.001
I41.1 Myocarditis in viral diseases classified elsewhere	0.000	0.999	0.001
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.000	0.999	0.001
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.000	0.999	0.001
I43.2 Cardiomyopathy in nutritional diseases	0.000	0.999	0.001
I43.1 Cardiomyopathy in metabolic diseases	0.000	0.999	0.001
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.000	0.999	0.001
I44.6 Other and unspecified fascicular block	0.000	0.999	0.001
I44.5 Left posterior fascicular block	0.000	0.999	0.001
I44.4 Left anterior fascicular block	0.000	0.999	0.001
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.000	0.999	0.001
I48.4 Atypical atrial flutter	0.000	0.999	0.001
I48.3 Typical atrial flutter	0.000	0.999	0.001
I48.2 Chronic atrial fibrillation	0.000	0.999	0.001
I48.1 Persistent atrial fibrillation	0.000	0.999	0.001
I48.0 Paroxysmal atrial fibrillation	0.000	0.999	0.001
I49.2 Junctional premature depolarisation	0.000	0.999	0.001
I49.1 Atrial premature depolarisation	0.000	0.999	0.001
I51.6 Cardiovascular disease, unspecified	0.000	0.999	0.001
I51.5 Myocardial degeneration	0.000	0.999	0.001
I51.4 Myocarditis, unspecified	0.000	0.999	0.001
I51.3 Intracardiac thrombosis, not elsewhere classified	0.000	0.999	0.001
I51.2 Rupture of papillary muscle, not elsewhere classified	0.000	0.999	0.001
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.000	0.999	0.001
I51.0 Cardiac septal defect, acquired	0.000	0.999	0.001
I52.8 Other heart disorders in other diseases classified elsewhere	0.000	0.999	0.001
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.999	0.001
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.000	0.999	0.001
I77.8 Other specified disorders of arteries and arterioles	0.000	0.999	0.001
I77.6 Arteritis, unspecified	0.000	0.999	0.001
I77.5 Necrosis of artery	0.000	0.999	0.001
I77.4 Coeliac artery compression syndrome	0.000	0.999	0.001
I77.3 Arterial fibromuscular dysplasia	0.000	0.999	0.001
I77.2 Rupture of artery	0.000	0.999	0.001
I77.0 Arteriovenous fistula, acquired	0.000	0.999	0.001
R09.2 Respiratory arrest	0.000	0.999	0.001
Z09.4 Follow-up examination after treatment of fracture	0.000	0.999	0.001
Z09.3 Follow-up examination after psychotherapy	0.000	0.999	0.001
Z09.1 Follow-up examination after radiotherapy for other conditions	0.000	0.999	0.001
I31.8 Other specified diseases of pericardium	0.000	0.999	0.001
I31.2 Haemopericardium, not elsewhere classified	0.000	0.999	0.001
I31.1 Chronic constrictive pericarditis	0.000	0.999	0.001
I31.0 Chronic adhesive pericarditis	0.000	0.999	0.001
I44.0 Atrioventricular block, first degree	0.000	0.999	0.001
I49.0 Ventricular fibrillation and flutter	0.000	0.999	0.001
R06.2 Wheezing	0.000	0.999	0.001
R09.1 Pleurisy	0.000	0.999	0.001
I05.9 Mitral valve disease, unspecified	0.000	0.999	0.001
I05.8 Other mitral valve diseases	0.000	0.999	0.001
I05.2 Mitral stenosis with insufficiency	0.000	0.999	0.001
I05.1 Rheumatic mitral insufficiency	0.000	0.999	0.001
I05.0 Mitral stenosis	0.000	0.999	0.001
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.999	0.001
I06.8 Other rheumatic aortic valve diseases	0.000	0.999	0.001
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.999	0.001
I06.1 Rheumatic aortic insufficiency	0.000	0.999	0.001
I06.0 Rheumatic aortic stenosis	0.000	0.999	0.001
I09.9 Rheumatic heart disease, unspecified	0.000	0.999	0.001
I09.8 Other specified rheumatic heart diseases	0.000	0.999	0.001
I09.2 Chronic rheumatic pericarditis	0.000	0.999	0.001
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.999	0.001
I09.0 Rheumatic myocarditis	0.000	0.999	0.001
I28.9 Disease of pulmonary vessels, unspecified	0.000	0.999	0.001
I28.8 Other specified diseases of pulmonary vessels	0.000	0.999	0.001
I28.1 Aneurysm of pulmonary artery	0.000	0.999	0.001
I28.0 Arteriovenous fistula of pulmonary vessels	0.000	0.999	0.001
I65.2 Occlusion and stenosis of carotid artery	0.000	0.999	0.001
I77.9 Disorder of arteries and arterioles, unspecified	0.000	0.999	0.001
R06.5 Mouth breathing	0.000	0.999	0.001
M81.99 Osteoporosis, unspecified (Site unspecified)	0.001	0.999	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.001	0.999	0.000
H04.5 Stenosis and insufficiency of lachrymal passages	0.000	0.999	0.001
H91.9 Hearing loss, unspecified	0.000	0.999	0.001
I72.9 Aneurysm of unspecified site	0.000	0.999	0.001
I72.8 Aneurysm of other specified arteries	0.000	0.999	0.001
I72.6 Aneurysm and dissection of vertebral artery	0.000	0.999	0.001
I72.5 Aneurysm and dissection of other precerebral arteries	0.000	0.999	0.001
I72.4 Aneurysm of artery of lower extremity	0.000	0.999	0.001
I72.3 Aneurysm of iliac artery	0.000	0.999	0.001
I72.2 Aneurysm of renal artery	0.000	0.999	0.001
I72.1 Aneurysm of artery of upper extremity	0.000	0.999	0.001
I72.0 Aneurysm of carotid artery	0.000	0.999	0.001
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.999	0.001
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.999	0.001
I79.1 Aortitis in diseases classified elsewhere	0.000	0.999	0.001
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.000	0.999	0.001
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.001	0.999	0.000
Z11 Special screening examination for infectious and parasitic diseases	0.000	0.999	0.001
S62.61 Fracture of other finger (open)	0.001	0.999	0.000
I27.0 Primary pulmonary hypertension	0.000	0.999	0.001
I44.2 Atrioventricular block, complete	0.000	0.999	0.001
I70.9 Generalised and unspecified atherosclerosis	0.000	0.999	0.001
I70.8 Atherosclerosis of other arteries	0.000	0.999	0.001
I70.1 Atherosclerosis of renal artery	0.000	0.999	0.001
I70.0 Atherosclerosis of aorta	0.000	0.999	0.001
K70.9 Alcoholic liver disease, unspecified	0.000	0.999	0.001
Z01.9 Special examination, unspecified	0.000	0.999	0.001
Z01.7 Laboratory examination	0.000	0.999	0.001
Z01.3 Examination of blood pressure	0.000	0.999	0.001
Z01.2 Dental examination	0.000	0.999	0.001
Z01.1 Examination of ears and hearing	0.000	0.999	0.001
Z01.0 Examination of eyes and vision	0.000	0.999	0.001
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.000	0.999	0.001
M81.98 Osteoporosis, unspecified (Other)	0.001	0.999	0.000
I27.9 Pulmonary heart disease, unspecified	0.000	0.999	0.001
I27.8 Other specified pulmonary heart diseases	0.000	0.999	0.001
I27.1 Kyphoscoliotic heart disease	0.000	0.999	0.001
M81.9 Osteoporosis, unspecified	0.001	0.999	0.000
R01.1 Cardiac murmur, unspecified	0.001	0.999	0.001
I42 Cardiomyopathy	0.000	0.999	0.001
I35 Nonrheumatic aortic valve disorders	0.000	0.999	0.001
T98 Sequelae of other and unspecified effects of external causes	0.001	0.999	0.000
Z02 Examination and encounter for administrative purposes	0.000	0.999	0.001
M43.16 Spondylolisthesis (Lumbar region)	0.001	0.999	0.000
I30.8 Other forms of acute pericarditis	0.000	0.999	0.001
I30.1 Infective pericarditis	0.000	0.999	0.001
I30.0 Acute nonspecific idiopathic pericarditis	0.000	0.999	0.001
I44.3 Other and unspecified atrioventricular block	0.000	0.999	0.001
I46.1 Sudden cardiac death, so described	0.000	0.999	0.001
I49.8 Other specified cardiac arrhythmias	0.000	0.999	0.001
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.999	0.001
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.001	0.999	0.000
S22.40 Multiple fractures of ribs (closed)	0.001	0.999	0.000
S62.30 Fracture of other metacarpal bone (closed)	0.001	0.999	0.000
I07.9 Tricuspid valve disease, unspecified	0.000	0.999	0.001
I07.8 Other tricuspid valve diseases	0.000	0.999	0.001
I07.2 Tricuspid stenosis with insufficiency	0.000	0.999	0.001
I07.0 Tricuspid stenosis	0.000	0.999	0.001
I46.9 Cardiac arrest, unspecified	0.000	0.999	0.001
I51.7 Cardiomegaly	0.000	0.999	0.001
I78.9 Disease of capillaries, unspecified	0.000	0.999	0.001
I78.8 Other diseases of capillaries	0.000	0.999	0.001
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations