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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1264420
log Bayes Factor = 25.6351
Chromosome 6   position 30,575,603  (GRCh37) Explore rs1264420 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.001 0.999
L40.0 Psoriasis vulgaris
0.000 0.076 0.924
L40.8 Other psoriasis
0.000 0.160 0.840
L40.1 Generalised pustular psoriasis
0.000 0.175 0.825
K90 Intestinal malabsorption
0.000 0.270 0.730
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.316 0.684
L40.3 Pustulosis palmaris et plantaris
0.000 0.351 0.648
E11 Non-insulin-dependent diabetes mellitus
0.000 0.395 0.605
E10-E14 Diabetes mellitus
0.000 0.395 0.605
E11.9 Without complications
0.000 0.396 0.604
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.422 0.578
E20-E35 Disorders of other endocrine glands
0.000 0.431 0.569
E11.6 With other specified complications
0.000 0.434 0.566
E23 Hypofunction and other disorders of pituitary gland
0.000 0.435 0.565
K90.8 Other intestinal malabsorption
0.000 0.442 0.558
E50-E64 Other nutritional deficiencies
0.000 0.447 0.553
E14 Unspecified diabetes mellitus
0.000 0.454 0.546
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.454 0.546
E24 Cushing's syndrome
0.000 0.455 0.545
E61 Deficiency of other nutrient elements
0.000 0.467 0.533
E10 Insulin-dependent diabetes mellitus
0.000 0.473 0.527
E23.7 Disorder of pituitary gland, unspecified
0.000 0.476 0.524
K90.3 Pancreatic steatorrhoea
0.000 0.477 0.523
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.477 0.523
K90.1 Tropical sprue
0.000 0.477 0.523
E61.1 Iron deficiency
0.000 0.479 0.521
E21.3 Hyperparathyroidism, unspecified
0.000 0.485 0.515
E23.2 Diabetes insipidus
0.000 0.485 0.515
E11.0 With coma
0.000 0.493 0.507
E10.3 With ophthalmic complications
0.000 0.494 0.506
E11.5 With peripheral circulatory complications
0.000 0.498 0.502
E53 Deficiency of other B group vitamins
0.000 0.505 0.495
E23.0 Hypopituitarism
0.000 0.510 0.490
E11.1 With ketoacidosis
0.000 0.511 0.489
E13 Other specified diabetes mellitus
0.000 0.514 0.486
E24.9 Cushing's syndrome, unspecified
0.000 0.525 0.475
E11.2 With renal complications
0.000 0.527 0.473
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.528 0.472
E24.0 Pituitary-dependent Cushing's disease
0.000 0.529 0.471
E24.2 Drug-induced Cushing's syndrome
0.000 0.538 0.462
E53.8 Deficiency of other specified B group vitamins
0.000 0.543 0.457
E23.6 Other disorders of pituitary gland
0.000 0.552 0.448
E10.2 With renal complications
0.000 0.557 0.443
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.559 0.441
E11.7 With multiple complications
0.000 0.566 0.434
E12 Malnutrition-related diabetes mellitus
0.000 0.566 0.433
E14.3 With ophthalmic complications
0.000 0.567 0.433
E14.4 With neurological complications
0.000 0.568 0.432
E14.8 With unspecified complications
0.000 0.570 0.430
E25 Adrenogenital disorders
0.000 0.576 0.423
E14.5 With peripheral circulatory complications
0.000 0.576 0.423
E14.1 With ketoacidosis
0.000 0.578 0.422
E10.1 With ketoacidosis
0.000 0.580 0.420
E10.9 Without complications
0.000 0.582 0.418
E00-E07 Disorders of thyroid gland
0.000 0.587 0.413
K90.9 Intestinal malabsorption, unspecified
0.000 0.590 0.410
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.590 0.410
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.592 0.408
E32 Diseases of thymus
0.000 0.592 0.408
E30 Disorders of puberty, not elsewhere classified
0.000 0.592 0.408
E14.2 Withrenal complications
0.000 0.592 0.407
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.595 0.405
E23.1 Drug-induced hypopituitarism
0.000 0.595 0.405
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.596 0.404
E13.9 Without complications
0.000 0.603 0.397
E56 Other vitamin deficiencies
0.000 0.603 0.397
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.603 0.397
E63 Other nutritional deficiencies
0.000 0.603 0.397
E50 Vitamin A deficiency
0.000 0.603 0.397
E60 Dietary zinc deficiency
0.000 0.603 0.397
E59 Dietary selenium deficiency
0.000 0.603 0.397
E52 Niacin deficiency [pellagra]
0.000 0.603 0.397
E51 Thiamine deficiency
0.000 0.605 0.395
E21.4 Other specified disorders of parathyroid gland
0.000 0.605 0.395
E14.7 With multiple complications
0.000 0.608 0.392
E14.0 With coma
0.000 0.608 0.392
E21.2 Other hyperparathyroidism
0.000 0.608 0.392
E24.8 Other Cushing's syndrome
0.000 0.609 0.391
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.609 0.391
E24.3 Ectopic ACTH syndrome
0.000 0.609 0.391
E24.1 Nelson's syndrome
0.000 0.609 0.391
E14.6 With other specified complications
0.000 0.611 0.388
E61.9 Deficiency of nutrient element, unspecified
0.000 0.618 0.382
E61.8 Deficiency of other specified nutrient elements
0.000 0.618 0.382
E61.7 Deficiency of multiple nutrient elements
0.000 0.618 0.382
E61.6 Vanadium deficiency
0.000 0.618 0.382
E61.5 Molybdenum deficiency
0.000 0.618 0.382
E61.4 Chromium deficiency
0.000 0.618 0.382
E61.3 Manganese deficiency
0.000 0.618 0.382
E61.0 Copper deficiency
0.000 0.618 0.382
E21.0 Primary hyperparathyroidism
0.000 0.619 0.381
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.622 0.378
E31 Polyglandular dysfunction
0.000 0.623 0.377
E58 Dietary calcium deficiency
0.000 0.625 0.375
E14.9 Without complications
0.000 0.628 0.372
E40-E46 Malnutrition
0.000 0.633 0.367
E20 Hypoparathyroidism
0.000 0.636 0.364
E10.0 With coma
0.000 0.638 0.362
E10.7 With multiple complications
0.000 0.640 0.360
E65-E68 Obesity and other hyperalimentation
0.000 0.642 0.358
E26 Hyperaldosteronism
0.000 0.643 0.357
E13.3 With ophthalmic complications
0.000 0.645 0.355
E53.1 Pyridoxine deficiency
0.000 0.645 0.355
E53.0 Riboflavin deficiency
0.000 0.645 0.355
E61.2 Magnesium deficiency
0.000 0.651 0.349
E13.8 With unspecified complications
0.000 0.651 0.349
E13.7 With multiple complications
0.000 0.651 0.349
E13.6 With other specified complications
0.000 0.651 0.349
E13.5 With peripheral circulatory complications
0.000 0.651 0.349
E13.4 With neurological complications
0.000 0.651 0.349
E13.2 With renal complications
0.000 0.651 0.349
E13.1 With ketoacidosis
0.000 0.651 0.349
E13.0 With coma
0.000 0.651 0.349
E10.4 With neurological complications
0.000 0.654 0.346
E53.9 Vitamin B deficiency, unspecified
0.000 0.656 0.344
E16 Other disorders of pancreatic internal secretion
0.000 0.657 0.343
E54 Ascorbic acid deficiency
0.000 0.660 0.340
E11.8 With unspecified complications
0.000 0.661 0.339
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.670 0.330
E55 Vitamin D deficiency
0.000 0.681 0.319
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.681 0.319
E22 Hyperfunction of pituitary gland
0.000 0.683 0.316
E15 Nondiabetic hypoglycaemic coma
0.000 0.683 0.316
E10.8 With unspecified complications
0.000 0.687 0.312
E12.9 Without complications
0.000 0.689 0.311
E12.8 With unspecified complications
0.000 0.689 0.311
E12.7 With multiple complications
0.000 0.689 0.311
E12.6 With other specified complications
0.000 0.689 0.311
E12.5 With peripheral circulatory complications
0.000 0.689 0.311
E12.4 With neurological complications
0.000 0.689 0.311
E12.3 With ophthalmic complications
0.000 0.689 0.311
E12.2 With renal complications
0.000 0.689 0.311
E12.1 With ketoacidosis
0.000 0.689 0.311
E12.0 With coma
0.000 0.689 0.311
E25.9 Adrenogenital disorder, unspecified
0.000 0.696 0.304
E25.8 Other adrenogenital disorders
0.000 0.696 0.304
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.703 0.296
E00 Congenital iodine-deficiency syndrome
0.000 0.703 0.296
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.706 0.294
E30.9 Disorder of puberty, unspecified
0.000 0.707 0.293
E30.8 Other disorders of puberty
0.000 0.707 0.293
E30.1 Precocious puberty
0.000 0.707 0.293
E30.0 Delayed puberty
0.000 0.707 0.293
E32.9 Disease of thymus, unspecified
0.000 0.707 0.293
E32.8 Other diseases of thymus
0.000 0.707 0.293
E32.1 Abscess of thymus
0.000 0.707 0.293
E32.0 Persistent hyperplasia of thymus
0.000 0.707 0.293
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.707 0.293
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.707 0.293
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.707 0.293
E05.5 Thyroid crisis or storm
0.000 0.710 0.290
E05.4 Thyrotoxicosis factitia
0.000 0.710 0.290
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.710 0.290
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.710 0.290
E29 Testicular dysfunction
0.000 0.712 0.287
E56.1 Deficiency of vitamin K
0.000 0.714 0.285
E56.9 Vitamin deficiency, unspecified
0.000 0.715 0.285
E56.8 Deficiency of other vitamins
0.000 0.715 0.285
E56.0 Deficiency of vitamin E
0.000 0.715 0.285
E50.9 Vitamin A deficiency, unspecified
0.000 0.715 0.284
E50.8 Other manifestations of vitamin A deficiency
0.000 0.715 0.284
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.715 0.284
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.715 0.284
E50.5 Vitamin A deficiency with night blindness
0.000 0.715 0.284
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.715 0.284
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.715 0.284
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.715 0.284
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.715 0.284
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.715 0.284
E63.9 Nutritional deficiency, unspecified
0.000 0.715 0.284
E63.8 Other specified nutritional deficiencies
0.000 0.715 0.284
E63.1 Imbalance of constituents of food intake
0.000 0.715 0.284
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.715 0.284
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.715 0.284
E64.8 Sequelae of other nutritional deficiencies
0.000 0.715 0.284
E64.3 Sequelae of rickets
0.000 0.715 0.284
E64.2 Sequelae of vitamin C deficiency
0.000 0.715 0.284
E64.1 Sequelae of vitamin A deficiency
0.000 0.715 0.284
E64.0 Sequelae of protein-energy malnutrition
0.000 0.715 0.284
E51.9 Thiamine deficiency, unspecified
0.000 0.716 0.283
E51.8 Other manifestations of thiamine deficiency
0.000 0.716 0.283
E51.1 Beriberi
0.000 0.716 0.283
E51.2 Wernicke's encephalopathy
0.000 0.718 0.282
E05.8 Other thyrotoxicosis
0.000 0.722 0.278
E28 Ovarian dysfunction
0.000 0.725 0.275
E31.9 Polyglandular dysfunction, unspecified
0.000 0.729 0.271
E31.8 Other polyglandular dysfunction
0.000 0.729 0.271
E31.1 Polyglandular hyperfunction
0.000 0.729 0.271
E22.0 Acromegaly and pituitary gigantism
0.000 0.730 0.270
E10.6 With other specified complications
0.000 0.731 0.269
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.737 0.263
E45 Retarded development following protein-energy malnutrition
0.000 0.737 0.263
E43 Unspecified severe protein-energy malnutrition
0.000 0.737 0.263
E42 Marasmic kwashiorkor
0.000 0.737 0.263
E41 Nutritional marasmus
0.000 0.737 0.263
E40 Kwashiorkor
0.000 0.737 0.263
E20.8 Other hypoparathyroidism
0.000 0.739 0.261
E20.1 Pseudohypoparathyroidism
0.000 0.739 0.261
E20.0 Idiopathic hypoparathyroidism
0.000 0.739 0.261
E67 Other hyperalimentation
0.000 0.743 0.257
E68 Sequelae of hyperalimentation
0.000 0.743 0.257
E16.1 Other hypoglycaemia
0.000 0.744 0.256
E26.8 Other hyperaldosteronism
0.000 0.744 0.256
E26.1 Secondary hyperaldosteronism
0.000 0.744 0.256
E26.9 Hyperaldosteronism, unspecified
0.000 0.750 0.250
E65 Localised adiposity
0.000 0.753 0.247
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.754 0.246
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.754 0.246
E16.4 Abnormal secretion of gastrin
0.000 0.754 0.246
E16.3 Increased secretion of glucagon
0.000 0.754 0.246
E31.0 Autoimmune polyglandular failure
0.000 0.760 0.240
E34 Other endocrine disorders
0.001 0.762 0.237
E83 Disorders of mineral metabolism
0.209 0.769 0.021
E55.0 Rickets, active
0.000 0.771 0.229
E05.9 Thyrotoxicosis, unspecified
0.000 0.771 0.229
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.773 0.227
E22.8 Other hyperfunction of pituitary gland
0.000 0.773 0.227
E20.9 Hypoparathyroidism, unspecified
0.000 0.783 0.217
E46 Unspecified protein-energy malnutrition
0.000 0.785 0.215
E66 Obesity
0.000 0.785 0.215
E03 Other hypothyroidism
0.000 0.785 0.215
E26.0 Primary hyperaldosteronism
0.000 0.787 0.213
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.787 0.213
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.787 0.213
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.787 0.213
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.787 0.213
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.787 0.213
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.787 0.213
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.787 0.213
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.787 0.213
E06 Thyroiditis
0.000 0.787 0.212
E29.8 Other testicular dysfunction
0.000 0.793 0.206
E29.0 Testicular hyperfunction
0.000 0.793 0.206
E07 Other disorders of thyroid
0.000 0.802 0.198
E28.9 Ovarian dysfunction, unspecified
0.000 0.803 0.197
E28.8 Other ovarian dysfunction
0.000 0.803 0.197
E28.1 Androgen excess
0.000 0.803 0.197
E28.0 Oestrogen excess
0.000 0.803 0.197
E10.5 With peripheral circulatory complications
0.001 0.811 0.189
E44.1 Mild protein-energy malnutrition
0.000 0.811 0.189
E44.0 Moderate protein-energy malnutrition
0.000 0.811 0.189
E16.2 Hypoglycaemia, unspecified
0.000 0.812 0.188
E67.8 Other specified hyperalimentation
0.000 0.815 0.184
E67.3 Hypervitaminosis D
0.000 0.815 0.184
E67.2 Megavitamin-B6 syndrome
0.000 0.815 0.184
E67.1 Hypercarotenaemia
0.000 0.815 0.184
E67.0 Hypervitaminosis A
0.000 0.815 0.184
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.817 0.183
E70-E90 Metabolic disorders
0.003 0.821 0.176
E83.3 Disorders of phosphorus metabolism
0.172 0.822 0.006
E03.8 Other specified hypothyroidism
0.000 0.823 0.177
E22.1 Hyperprolactinaemia
0.000 0.825 0.174
E83.9 Disorder of mineral metabolism, unspecified
0.160 0.826 0.014
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.827 0.173
E28.3 Primary ovarian failure
0.000 0.827 0.172
E29.9 Testicular dysfunction, unspecified
0.000 0.829 0.171
E34.5 Androgen resistance syndrome
0.001 0.829 0.170
E34.4 Constitutional tall stature
0.001 0.829 0.170
E34.3 Short stature, not elsewhere classified
0.001 0.829 0.170
E34.2 Ectopic hormone secretion, not elsewhere classified
0.001 0.829 0.170
E34.1 Other hypersecretion of intestinal hormones
0.001 0.829 0.170
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.832 0.168
E83.8 Other disorders of mineral metabolism
0.150 0.834 0.016
E83.2 Disorders of zinc metabolism
0.150 0.834 0.016
E83.0 Disorders of copper metabolism
0.150 0.834 0.016
E06.5 Other chronic thyroiditis
0.000 0.835 0.165
E66.8 Other obesity
0.000 0.843 0.157
E34.9 Endocrine disorder, unspecified
0.000 0.844 0.155
E66.0 Obesity due to excess calories
0.000 0.845 0.155
E66.1 Drug-induced obesity
0.000 0.845 0.154
E03.5 Myxoedema coma
0.000 0.846 0.154
E03.4 Atrophy of thyroid (acquired)
0.000 0.846 0.154
E03.3 Postinfectious hypothyroidism
0.000 0.846 0.154
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.846 0.154
E06.4 Drug-induced thyroiditis
0.000 0.847 0.152
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.847 0.152
E06.1 Subacute thyroiditis
0.000 0.847 0.152
E06.0 Acute thyroiditis
0.000 0.847 0.152
E55.9 Vitamin D deficiency, unspecified
0.000 0.848 0.152
E27 Other disorders of adrenal gland
0.000 0.851 0.149
E78.2 Mixed hyperlipidaemia
0.000 0.851 0.149
E29.1 Testicular hypofunction
0.000 0.853 0.147
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.854 0.146
E34.8 Other specified endocrine disorders
0.001 0.854 0.145
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.001 0.855 0.144
E78.1 Pure hyperglyceridaemia
0.000 0.858 0.142
E07.1 Dyshormogenetic goitre
0.000 0.858 0.142
E07.0 Hypersecretion of calcitonin
0.000 0.858 0.142
L40-L45 Papulosquamous disorders
0.000 0.859 0.141
E06.9 Thyroiditis, unspecified
0.000 0.859 0.141
E07.8 Other specified disorders of thyroid
0.000 0.861 0.139
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.002 0.863 0.135
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.864 0.136
E87.2 Acidosis
0.000 0.866 0.134
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.867 0.133
E78.0 Pure hypercholesterolaemia
0.000 0.868 0.132
E87.7 Fluid overload
0.000 0.868 0.132
E84 Cystic fibrosis
0.002 0.868 0.130
E79 Disorders of purine and pyrimidine metabolism
0.002 0.869 0.129
E77 Disorders of glycoprotein metabolism
0.002 0.871 0.127
E76 Disorders of glycosaminoglycan metabolism
0.002 0.871 0.127
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.002 0.871 0.127
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.002 0.871 0.127
E78.8 Other disorders of lipoprotein metabolism
0.000 0.872 0.128
E72 Other disorders of amino-acid metabolism
0.002 0.873 0.125
E78.6 Lipoprotein deficiency
0.000 0.874 0.126
E88 Other metabolic disorders
0.001 0.874 0.125
E11.4 With neurological complications
0.000 0.877 0.123
E03.1 Congenital hypothyroidism without goitre
0.000 0.877 0.122
E70 Disorders of aromatic amino-acid metabolism
0.002 0.879 0.119
E89.3 Postprocedural hypopituitarism
0.000 0.880 0.120
E78.4 Other hyperlipidaemia
0.000 0.880 0.120
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.883 0.117
E28.2 Polycystic ovarian syndrome
0.000 0.886 0.114
E27.9 Disorder of adrenal gland, unspecified
0.000 0.889 0.111
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.890 0.109
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.892 0.108
E27.5 Adrenomedullary hyperfunction
0.000 0.893 0.107
E27.0 Other adrenocortical overactivity
0.000 0.893 0.107
E73 Lactose intolerance
0.002 0.893 0.105
E75.5 Other lipid storage disorders
0.001 0.893 0.105
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.894 0.106
E74 Other disorders of carbohydrate metabolism
0.002 0.896 0.102
E78.3 Hyperchylomicronaemia
0.000 0.897 0.103
A08.4 Viral intestinal infection, unspecified
0.000 0.897 0.103
E88.8 Other specified metabolic disorders
0.001 0.897 0.102
E89.2 Postprocedural hypoparathyroidism
0.000 0.898 0.102
L44 Other papulosquamous disorders
0.000 0.899 0.101
L41 Parapsoriasis
0.000 0.899 0.101
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.899 0.101
E83.4 Disorders of magnesium metabolism
0.091 0.901 0.008
E75.6 Lipid storage disorder, unspecified
0.001 0.902 0.097
E75.4 Neuronal ceroid lipofuscinosis
0.001 0.902 0.097
E75.3 Sphingolipidosis, unspecified
0.001 0.902 0.097
E75.2 Other sphingolipidosis
0.001 0.902 0.097
E75.1 Other gangliosidosis
0.001 0.902 0.097
E75.0 GM2 gangliosidosis
0.001 0.902 0.097
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.001 0.902 0.098
E84.9 Cystic fibrosis, unspecified
0.001 0.902 0.097
E87.4 Mixed disorder of acid-base balance
0.000 0.902 0.097
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.001 0.903 0.096
E88.2 Lipomatosis, not elsewhere classified
0.001 0.903 0.096
E34.0 Carcinoid syndrome
0.001 0.904 0.095
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.904 0.095
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.904 0.095
E89.5 Postprocedural testicular hypofunction
0.000 0.904 0.095
E89.1 Postprocedural hypoinsulinaemia
0.000 0.904 0.095
E84.8 Cystic fibrosis with other manifestations
0.002 0.905 0.093
E84.1 Cystic fibrosis with intestinal manifestations
0.002 0.905 0.093
E84.0 Cystic fibrosis with pulmonary manifestations
0.002 0.905 0.093
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.002 0.906 0.093
E79.8 Other disorders of purine and pyrimidine metabolism
0.002 0.906 0.093
E79.1 Lesch-Nyhan syndrome
0.002 0.906 0.093
E71.3 Disorders of fatty-acid metabolism
0.002 0.907 0.091
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.002 0.907 0.091
E71.1 Other disorders of branched-chain amino-acid metabolism
0.002 0.907 0.091
E71.0 Maple-syrup-urine disease
0.002 0.907 0.091
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.002 0.907 0.091
E76.8 Other disorders of glucosaminoglycan metabolism
0.002 0.907 0.091
E76.3 Mucopolysaccharidosis, unspecified
0.002 0.907 0.091
E76.2 Other mucopolysaccharidoses
0.002 0.907 0.091
E76.1 Mucopolysaccharidosis, type II
0.002 0.907 0.091
E76.0 Mucopolysaccharidosis, type I
0.002 0.907 0.091
E77.9 Disorder of glycoprotein metabolism, unspecified
0.002 0.907 0.091
E77.8 Other disorders of glycoprotein metabolism
0.002 0.907 0.091
E77.1 Defects in glycoprotein degradation
0.002 0.907 0.091
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.002 0.907 0.091
E72.9 Disorder of amino-acid metabolism, unspecified
0.002 0.909 0.090
E72.8 Other specified disorders of amino-acid metabolism
0.002 0.909 0.090
E72.5 Disorders of glycine metabolism
0.002 0.909 0.090
E72.4 Disorders of ornithine metabolism
0.002 0.909 0.090
E72.3 Disorders of lysine and hydroxylysine metabolism
0.002 0.909 0.090
E72.2 Disorders of urea cycle metabolism
0.002 0.909 0.090
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.002 0.909 0.090
E86 Volume depletion
0.000 0.909 0.091
E72.0 Disorders of amino-acid transport
0.002 0.910 0.088
E88.3 Tumour lysis syndrome
0.001 0.910 0.089
E88.9 Metabolic disorder, unspecified
0.001 0.911 0.088
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.002 0.913 0.085
E70.8 Other disorders of aromatic amino-acid metabolism
0.002 0.913 0.085
E70.2 Disorders of tyrosine metabolism
0.002 0.913 0.085
E70.1 Other hyperphenylalaninaemias
0.002 0.913 0.085
E70.0 Classical phenylketonuria
0.002 0.913 0.085
E11.3 With ophthalmic complications
0.000 0.915 0.085
E88.1 Lipodystrophy, not elsewhere classified
0.001 0.919 0.081
E89.4 Postprocedural ovarian failure
0.001 0.920 0.080
E70.3 Albinism
0.002 0.921 0.078
E78.5 Hyperlipidaemia, unspecified
0.000 0.923 0.077
E73.8 Other lactose intolerance
0.002 0.923 0.075
E73.1 Secondary lactase deficiency
0.002 0.923 0.075
E73.0 Congenital lactase deficiency
0.002 0.923 0.075
E87.6 Hypokalaemia
0.000 0.924 0.076
E74.9 Disorder of carbohydrate metabolism, unspecified
0.002 0.925 0.073
E74.8 Other specified disorders of carbohydrate metabolism
0.002 0.925 0.073
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.002 0.925 0.073
E74.2 Disorders of galactose metabolism
0.002 0.925 0.073
E74.1 Disorders of fructose metabolism
0.002 0.925 0.073
E85 Amyloidosis
0.003 0.927 0.070
L41.9 Parapsoriasis, unspecified
0.000 0.927 0.073
L41.8 Other parapsoriasis
0.000 0.927 0.073
L41.5 Retiform parapsoriasis
0.000 0.927 0.073
L41.4 Large plaque parapsoriasis
0.000 0.927 0.073
L41.3 Small plaque parapsoriasis
0.000 0.927 0.073
L41.2 Lymphomatoid papulosis
0.000 0.927 0.073
L41.1 Pityriasis lichenoides chronica
0.000 0.927 0.073
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.927 0.073
L44.9 Papulosquamous disorder, unspecified
0.000 0.927 0.073
L44.8 Other specified papulosquamous disorders
0.000 0.927 0.073
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.927 0.073
L44.3 Lichen ruber moniliformis
0.000 0.927 0.073
L44.2 Lichen striatus
0.000 0.927 0.073
L44.1 Lichen nitidus
0.000 0.927 0.073
L44.0 Pityriasis rubra pilaris
0.000 0.927 0.073
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.927 0.072
E74.0 Glycogen storage disease
0.002 0.929 0.069
E87.3 Alkalosis
0.000 0.938 0.062
E06.3 Autoimmune thyroiditis
0.000 0.938 0.061
L43 Lichen planus
0.000 0.939 0.061
E04 Other non-toxic goitre
0.000 0.940 0.060
E27.2 Addisonian crisis
0.001 0.942 0.057
E74.3 Other disorders of intestinal carbohydrate absorption
0.002 0.942 0.056
E27.8 Other specified disorders of adrenal gland
0.001 0.944 0.055
E73.9 Lactose intolerance, unspecified
0.002 0.945 0.053
L42 Pityriasis rosea
0.001 0.946 0.053
A08 Viral and other specified intestinal infections
0.000 0.947 0.053
E85.2 Heredofamilial amyloidosis, unspecified
0.002 0.947 0.051
E85.1 Neuropathic heredofamilial amyloidosis
0.002 0.947 0.051
E85.0 Nonneuropathic heredofamilial amyloidosis
0.002 0.947 0.051
E07.9 Disorder of thyroid, unspecified
0.000 0.949 0.051
E85.8 Other amyloidosis
0.002 0.949 0.049
E27.1 Primary adrenocortical insufficiency
0.001 0.951 0.049
E85.4 Organ-limited amyloidosis
0.002 0.952 0.046
E04.0 Non-toxic diffuse goitre
0.000 0.954 0.046
L43.3 Subacute (active) lichen planus
0.000 0.956 0.044
L43.2 Lichenoid drug reaction
0.000 0.956 0.044
L43.1 Bullous lichen planus
0.000 0.956 0.044
L43.0 Hypertrophic lichen planus
0.000 0.956 0.044
E80 Disorders of porphyrin and bilirubin metabolism
0.003 0.956 0.041
E04.8 Other specified non-toxic goitre
0.000 0.956 0.043
K90-K93 Other diseases of the digestive system
0.000 0.957 0.043
E85.3 Secondary systemic amyloidosis
0.002 0.957 0.041
L43.8 Other lichen planus
0.000 0.959 0.041
A08.3 Other viral enteritis
0.000 0.959 0.041
A08.1 Acute gastro-enteropathy due to Norwalk agent
0.000 0.960 0.040
A08.5 Other specified intestinal infections
0.000 0.962 0.038
A08.2 Adenoviral enteritis
0.000 0.962 0.038
A08.0 Rotaviral enteritis
0.000 0.962 0.038
E85.9 Amyloidosis, unspecified
0.002 0.965 0.032
E80.7 Disorder of bilirubin metabolism, unspecified
0.002 0.968 0.030
E80.5 Crigler-Najjar syndrome
0.002 0.968 0.030
E80.3 Defects of catalase and peroxydase
0.002 0.968 0.030
E80.0 Hereditary erythropoietic porphyria
0.002 0.968 0.030
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.969 0.031
E87.0 Hyperosmolality and hypernatraemia
0.000 0.969 0.030
E80.6 Other disorders of bilirubin metabolism
0.002 0.971 0.027
E04.9 Non-toxic goitre, unspecified
0.000 0.972 0.028
E80.2 Other porphyria
0.002 0.973 0.025
E83.5 Disorders of calcium metabolism
0.014 0.974 0.012
E80.1 Porphyria cutanea tarda
0.003 0.977 0.020
N18.5 Chronic kidney disease, stage 5
0.000 0.977 0.023
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.977 0.022
K93.1 Megacolon in Chagas' disease
0.000 0.977 0.022
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.977 0.022
E87.5 Hyperkalaemia
0.000 0.982 0.018
N18 Chronic renal failure
0.000 0.983 0.017
N18.0 End-stage renal disease
0.000 0.984 0.016
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.984 0.016
E89.0 Postprocedural hypothyroidism
0.000 0.985 0.015
E66.9 Obesity, unspecified
0.000 0.985 0.015
E87.1 Hypo-osmolality and hyponatraemia
0.000 0.985 0.014
N18.4 Chronic kidney disease, stage 4
0.000 0.986 0.014
M07.3 Other psoriatic arthropathies
0.000 0.987 0.013
N18.1 Chronic kidney disease, stage 1
0.000 0.987 0.013
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.988 0.012
E80.4 Gilbert's syndrome
0.002 0.988 0.010
L43.9 Lichen planus, unspecified
0.000 0.988 0.012
E04.1 Non-toxic single thyroid nodule
0.000 0.988 0.012
N18.9 Chronic renal failure, unspecified
0.000 0.989 0.011
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.989 0.011
M50.1 Cervical disk disorder with radiculopathy
0.000 0.989 0.011
N18.3 Chronic kidney disease, stage 3
0.000 0.989 0.011
N18.8 Other chronic renal failure
0.000 0.989 0.011
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.989 0.010
N18.2 Chronic kidney disease, stage 2
0.000 0.990 0.010
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.990 0.010
M07.38 Other psoriatic arthropathies (Other)
0.000 0.990 0.010
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.990 0.010
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.990 0.010
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.990 0.010
M70.65 Trochanteric bursitis-Pelvic/Thigh
0.000 0.990 0.010
Z99.2 Dependence on renal dialysis
0.000 0.991 0.009
W13.9 Unspecified place
0.000 0.991 0.009
L30.9 Dermatitis, unspecified
0.009 0.991 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.991 0.008

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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