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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1264539
log Bayes Factor = 24.7934
Chromosome 6   position 30,388,701  (GRCh37) Explore rs1264539 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
G35 Multiple sclerosis
0.982 0.018 0.000
E10.9 Without complications
0.000 0.024 0.976
G35-G37 Demyelinating diseases of the central nervous system
0.973 0.027 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.029 0.971
G20-G26 Extrapyramidal and movement disorders
0.969 0.031 0.000
G25 Other extrapyramidal and movement disorders
0.964 0.036 0.000
G24 Dystonia
0.958 0.042 0.000
Chapter VI Diseases of the nervous system
0.958 0.042 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.957 0.043 0.000
E10.3 With ophthalmic complications
0.000 0.048 0.952
M06.9 Rheumatoid arthritis, unspecified
0.000 0.079 0.921
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.086 0.914
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.089 0.911
E10.2 With renal complications
0.000 0.123 0.877
G24.8 Other dystonia
0.875 0.125 0.000
G90-G99 Other disorders of the nervous system
0.874 0.126 0.000
E10.1 With ketoacidosis
0.000 0.136 0.864
G37 Other demyelinating diseases of central nervous system
0.861 0.139 0.000
G24.9 Dystonia, unspecified
0.854 0.146 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.148 0.852
G99 Other disorders of nervous system in diseases classified elsewhere
0.845 0.155 0.000
G93 Other disorders of brain
0.824 0.176 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.180 0.820
G24.3 Spasmodic torticollis
0.819 0.181 0.000
G25.5 Other chorea
0.812 0.187 0.000
G93.4 Encephalopathy, unspecified
0.812 0.188 0.000
E10.4 With neurological complications
0.000 0.190 0.810
G99.2 Myelopathy in diseases classified elsewhere
0.807 0.193 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.804 0.196 0.000
G24.0 Drug-induced dystonia
0.798 0.202 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.208 0.792
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.208 0.792
G20 Parkinson's disease
0.789 0.211 0.000
G25.1 Drug-induced tremor
0.779 0.221 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.237 0.763
G96 Other disorders of central nervous system
0.761 0.239 0.000
E10.0 With coma
0.000 0.241 0.759
G24.5 Blepharospasm
0.750 0.250 0.000
G30-G32 Other degenerative diseases of the nervous system
0.746 0.254 0.000
K90 Intestinal malabsorption
0.000 0.266 0.734
G21 Secondary Parkinsonism
0.723 0.277 0.000
G25.3 Myoclonus
0.716 0.284 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.285 0.715
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.710 0.290 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.706 0.294 0.000
G23 Other degenerative diseases of basal ganglia
0.703 0.297 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.298 0.702
G93.8 Other specified disorders of brain
0.699 0.301 0.000
G36 Other acute disseminated demyelination
0.698 0.302 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.694 0.305 0.000
G22 Parkinsonism in diseases classified elsewhere
0.694 0.305 0.000
G25.6 Drug-induced tics and other tics of organic origin
0.691 0.309 0.000
G25.4 Drug-induced chorea
0.691 0.309 0.000
G25.2 Other specified forms of tremor
0.691 0.309 0.000
G24.4 Idiopathic orofacial dystonia
0.687 0.313 0.000
G24.2 Idiopathic nonfamilial dystonia
0.687 0.313 0.000
G24.1 Idiopathic familial dystonia
0.687 0.313 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.681 0.319 0.000
G25.9 Extrapyramidal and movement disorder, unspecified
0.662 0.338 0.000
E10.8 With unspecified complications
0.000 0.340 0.660
G96.0 Cerebrospinal fluid leak
0.650 0.350 0.000
E10-E14 Diabetes mellitus
0.000 0.355 0.645
G92 Toxic encephalopathy
0.627 0.373 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.375 0.625
G40-G47 Episodic and paroxysmal disorders
0.623 0.377 0.000
G93.3 Postviral fatigue syndrome
0.620 0.380 0.000
G37.5 Concentric sclerosis [Balo]
0.618 0.382 0.000
G37.4 Subacute necrotising myelitis
0.618 0.382 0.000
G37.2 Central pontine myelinolysis
0.618 0.382 0.000
G37.1 Central demyelination of corpus callosum
0.618 0.382 0.000
G37.0 Diffuse sclerosis
0.618 0.382 0.000
G96.1 Disorders of meninges, not elsewhere classified
0.614 0.386 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.609 0.391 0.000
G25.0 Essential tremor
0.607 0.393 0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere
0.606 0.394 0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere
0.606 0.394 0.000
E10.7 With multiple complications
0.000 0.395 0.605
K90.9 Intestinal malabsorption, unspecified
0.000 0.400 0.600
E10.6 With other specified complications
0.000 0.403 0.596
G00-G09 Inflammatory diseases of the central nervous system
0.594 0.406 0.000
G97.8 Other postprocedural disorders of nervous system
0.592 0.408 0.000
G93.7 Reye's syndrome
0.591 0.409 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.580 0.419 0.000
G93.6 Cerebral oedema
0.580 0.420 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.579 0.421 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.575 0.425 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.569 0.431 0.000
K90.8 Other intestinal malabsorption
0.000 0.435 0.565
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.565 0.435 0.000
E10.5 With peripheral circulatory complications
0.000 0.439 0.561
G31.2 Degeneration of nervous system due to alcohol
0.553 0.447 0.000
E13 Other specified diabetes mellitus
0.000 0.448 0.552
G21.1 Other drug-induced secondary Parkinsonism
0.548 0.452 0.000
G96.9 Disorder of central nervous system, unspecified
0.546 0.454 0.000
G93.5 Compression of brain
0.544 0.456 0.000
G41 Status epilepticus
0.539 0.461 0.000
G40 Epilepsy
0.536 0.464 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.535 0.465 0.000
G96.8 Other specified disorders of central nervous system
0.534 0.466 0.000
G93.2 Benign intracranial hypertension
0.531 0.469 0.000
G46.7 Other lacunar syndromes
0.530 0.470 0.000
K90.3 Pancreatic steatorrhoea
0.000 0.473 0.526
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.473 0.526
K90.1 Tropical sprue
0.000 0.473 0.526
E03.9 Hypothyroidism, unspecified
0.000 0.477 0.523
G21.9 Secondary Parkinsonism, unspecified
0.519 0.481 0.000
G21.8 Other secondary Parkinsonism
0.519 0.481 0.000
G21.4 Vascular parkinsonism
0.519 0.481 0.000
G21.3 Postencephalitic Parkinsonism
0.519 0.481 0.000
G21.2 Secondary Parkinsonism due to other external agents
0.519 0.481 0.000
G21.0 Malignant neuroleptic syndrome
0.519 0.481 0.000
G23.8 Other specified degenerative diseases of basal ganglia
0.512 0.488 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.488 0.511
G30 Alzheimer's disease
0.511 0.489 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.492 0.508
E03 Other hypothyroidism
0.000 0.493 0.507
G31.9 Degenerative disease of nervous system, unspecified
0.506 0.494 0.000
G23.9 Degenerative disease of basal ganglia, unspecified
0.504 0.496 0.000
G23.3 Multiple system atrophy, cerebellar type
0.504 0.496 0.000
G23.2 Striatonigral degeneration
0.504 0.496 0.000
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]
0.504 0.496 0.000
G23.0 Hallervorden-Spatz disease
0.504 0.496 0.000
E00-E07 Disorders of thyroid gland
0.000 0.497 0.503
G36.9 Acute disseminated demyelination, unspecified
0.500 0.499 0.000
G36.8 Other specified acute disseminated demyelination
0.500 0.499 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.500 0.499 0.000
G36.0 Neuromyelitis optica [Devic]
0.500 0.499 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.494 0.506 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.492 0.508 0.000
G97.9 Postprocedural disorder of nervous system, unspecified
0.488 0.511 0.000
G97.2 Intracranial hypotension following ventricular shunting
0.488 0.511 0.000
E13.9 Without complications
0.000 0.514 0.486
G94 Other disorders of brain in diseases classified elsewhere
0.479 0.521 0.000
G41.9 Status epilepticus, unspecified
0.470 0.530 0.000
E14 Unspecified diabetes mellitus
0.000 0.534 0.466
E12 Malnutrition-related diabetes mellitus
0.000 0.537 0.462
G03 Meningitis due to other and unspecified causes
0.462 0.538 0.000
E50-E64 Other nutritional deficiencies
0.000 0.541 0.459
G06 Intracranial and intraspinal abscess and granuloma
0.458 0.541 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.457 0.542 0.000
E07 Other disorders of thyroid
0.000 0.553 0.447
G97.1 Other reaction to spinal and lumbar puncture
0.444 0.556 0.000
G11 Hereditary ataxia
0.439 0.561 0.000
G97.0 Cerebrospinal fluid leak from spinal puncture
0.438 0.562 0.000
G31.1 Senile degeneration of brain, not elsewhere classified
0.436 0.563 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.426 0.574 0.000
G43 Migraine
0.422 0.578 0.000
G31.0 Circumscribed brain atrophy
0.419 0.581 0.000
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere
0.419 0.581 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.417 0.583 0.000
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere
0.415 0.584 0.000
G14 Postpolio syndrome
0.415 0.584 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.590 0.410
G46.4 Cerebellar stroke syndrome
0.409 0.591 0.000
G95 Other diseases of spinal cord
0.408 0.591 0.000
G46.8 Other vascular syndromes of brain in cerebrovascular diseases
0.408 0.592 0.000
G46.6 Pure sensory lacunar syndrome
0.408 0.592 0.000
G46.5 Pure motor lacunar syndrome
0.408 0.592 0.000
G46.3 Brain stem stroke syndrome
0.408 0.592 0.000
G46.2 Posterior cerebral artery syndrome
0.408 0.592 0.000
G46.1 Anterior cerebral artery syndrome
0.408 0.592 0.000
G46.0 Middle cerebral artery syndrome
0.408 0.592 0.000
G41.0 Grand mal status epilepticus
0.408 0.592 0.000
G30.8 Other Alzheimer's disease
0.408 0.592 0.000
G40.5 Special epileptic syndromes
0.407 0.593 0.000
E14.3 With ophthalmic complications
0.000 0.593 0.407
G10 Huntington's disease
0.406 0.593 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.595 0.405
G04 Encephalitis, myelitis and encephalomyelitis
0.403 0.597 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.603 0.397
E13.8 With unspecified complications
0.000 0.604 0.396
E13.7 With multiple complications
0.000 0.604 0.396
E13.6 With other specified complications
0.000 0.604 0.396
E13.5 With peripheral circulatory complications
0.000 0.604 0.396
E13.4 With neurological complications
0.000 0.604 0.396
E13.3 With ophthalmic complications
0.000 0.604 0.396
E13.2 With renal complications
0.000 0.604 0.396
E13.1 With ketoacidosis
0.000 0.604 0.396
E13.0 With coma
0.000 0.604 0.396
E61 Deficiency of other nutrient elements
0.000 0.612 0.388
G30.0 Alzheimer's disease with early onset
0.388 0.612 0.000
G41.8 Other status epilepticus
0.387 0.613 0.000
G41.2 Complex partial status epilepticus
0.387 0.613 0.000
G41.1 Petit mal status epilepticus
0.387 0.613 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.384 0.615 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.384 0.616 0.000
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere
0.383 0.616 0.000
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere
0.383 0.616 0.000
G00 Bacterial meningitis, not elsewhere classified
0.375 0.625 0.000
E06 Thyroiditis
0.000 0.626 0.374
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.373 0.627 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.373 0.627 0.000
E03.8 Other specified hypothyroidism
0.000 0.628 0.372
G06.2 Extradural and subdural abscess, unspecified
0.371 0.629 0.000
L40.9 Psoriasis, unspecified
0.370 0.630 0.000
G40.8 Other epilepsy
0.369 0.631 0.000
E55 Vitamin D deficiency
0.000 0.631 0.369
E14.8 With unspecified complications
0.000 0.632 0.368
E53 Deficiency of other B group vitamins
0.000 0.632 0.368
G03.9 Meningitis, unspecified
0.368 0.632 0.000
G30.1 Alzheimer's disease with late onset
0.367 0.633 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.365 0.634 0.000
G40.9 Epilepsy, unspecified
0.365 0.635 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.364 0.636 0.000
E03.5 Myxoedema coma
0.000 0.636 0.364
E03.4 Atrophy of thyroid (acquired)
0.000 0.636 0.364
E03.3 Postinfectious hypothyroidism
0.000 0.636 0.364
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.636 0.364
E14.1 With ketoacidosis
0.000 0.637 0.363
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.639 0.361
E00 Congenital iodine-deficiency syndrome
0.000 0.639 0.361
G43.8 Other migraine
0.359 0.641 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.354 0.646 0.000
E61.1 Iron deficiency
0.000 0.646 0.354
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere
0.353 0.647 0.000
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere
0.353 0.647 0.000
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere
0.353 0.647 0.000
G06.1 Intraspinal abscess and granuloma
0.349 0.651 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.345 0.655 0.000
G94.8 Other specified disorders of brain in diseases classified elsewhere
0.343 0.656 0.000
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere
0.343 0.656 0.000
E07.8 Other specified disorders of thyroid
0.000 0.657 0.343
E16 Other disorders of pancreatic internal secretion
0.000 0.659 0.341
E58 Dietary calcium deficiency
0.000 0.663 0.337
E14.7 With multiple complications
0.000 0.666 0.334
E14.6 With other specified complications
0.000 0.666 0.334
E14.2 Withrenal complications
0.000 0.666 0.334
E14.0 With coma
0.000 0.666 0.334
G11.1 Early-onset cerebellar ataxia
0.333 0.666 0.000
E12.9 Without complications
0.000 0.668 0.332
E12.8 With unspecified complications
0.000 0.668 0.332
E12.7 With multiple complications
0.000 0.668 0.332
E12.6 With other specified complications
0.000 0.668 0.332
E12.5 With peripheral circulatory complications
0.000 0.668 0.332
E12.4 With neurological complications
0.000 0.668 0.332
E12.3 With ophthalmic complications
0.000 0.668 0.332
E12.2 With renal complications
0.000 0.668 0.332
E12.1 With ketoacidosis
0.000 0.668 0.332
E12.0 With coma
0.000 0.668 0.332
G03.8 Meningitis due to other specified causes
0.331 0.668 0.000
G03.2 Benign recurrent meningitis [Mollaret]
0.331 0.668 0.000
G03.1 Chronic meningitis
0.331 0.668 0.000
G03.0 Nonpyogenic meningitis
0.331 0.668 0.000
G04.8 Other encephalitis, myelitis and encephalomyelitis
0.331 0.669 0.000
G70-G73 Diseases of myoneural junction and muscle
0.329 0.670 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.671 0.329
E63 Other nutritional deficiencies
0.000 0.671 0.329
E51 Thiamine deficiency
0.000 0.671 0.329
E50 Vitamin A deficiency
0.000 0.671 0.329
E60 Dietary zinc deficiency
0.000 0.671 0.329
E59 Dietary selenium deficiency
0.000 0.671 0.329
E54 Ascorbic acid deficiency
0.000 0.671 0.329
E52 Niacin deficiency [pellagra]
0.000 0.671 0.329
G11.4 Hereditary spastic paraplegia
0.327 0.673 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.325 0.675 0.000
G95.0 Syringomyelia and syringobulbia
0.324 0.676 0.000
E07.1 Dyshormogenetic goitre
0.000 0.680 0.320
E07.0 Hypersecretion of calcitonin
0.000 0.680 0.320
E14.4 With neurological complications
0.000 0.680 0.320
E56 Other vitamin deficiencies
0.000 0.683 0.317
G43.0 Migraine without aura [common migraine]
0.315 0.685 0.000
G11.8 Other hereditary ataxias
0.315 0.685 0.000
G11.3 Cerebellar ataxia with defective DNA repair
0.315 0.685 0.000
G11.2 Late-onset cerebellar ataxia
0.315 0.685 0.000
G11.0 Congenital nonprogressive ataxia
0.315 0.685 0.000
G95.2 Cord compression, unspecified
0.312 0.688 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.691 0.309
G44 Other headache syndromes
0.308 0.692 0.000
G11.9 Hereditary ataxia, unspecified
0.308 0.692 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.693 0.307
E14.5 With peripheral circulatory complications
0.000 0.695 0.305
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.305 0.695 0.000
E55.9 Vitamin D deficiency, unspecified
0.000 0.696 0.304
G43.3 Complicated migraine
0.303 0.697 0.000
G43.2 Status migrainosus
0.303 0.697 0.000
E53.8 Deficiency of other specified B group vitamins
0.000 0.701 0.299
L40 Psoriasis
0.299 0.701 0.000
G13.8 Systemic atrophy primarily affecting central nervous system in other diseases classified elsewhere
0.298 0.702 0.000
G13.2 Systemic atrophy primarily affecting central nervous system in myxoedema
0.298 0.702 0.000
G13.1 Other systemic atrophy primarily affecting central nervous system in neoplastic disease
0.298 0.702 0.000
G13.0 Paraneoplastic neuromyopathy and neuropathy
0.298 0.702 0.000
E03.1 Congenital hypothyroidism without goitre
0.000 0.702 0.298
E15 Nondiabetic hypoglycaemic coma
0.000 0.706 0.294
E06.3 Autoimmune thyroiditis
0.000 0.706 0.294
G94.1 Hydrocephalus in neoplastic disease
0.293 0.707 0.000
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified
0.289 0.711 0.000
G04.1 Tropical spastic paraplegia
0.289 0.711 0.000
G04.0 Acute disseminated encephalitis
0.289 0.711 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.711 0.289
E40-E46 Malnutrition
0.000 0.712 0.288
G64 Other disorders of peripheral nervous system
0.288 0.712 0.000
G06.0 Intracranial abscess and granuloma
0.287 0.712 0.000
G60 Hereditary and idiopathic neuropathy
0.286 0.714 0.000
G00.2 Streptococcal meningitis
0.284 0.716 0.000
G43.1 Migraine with aura [classical migraine]
0.280 0.720 0.000
E16.1 Other hypoglycaemia
0.000 0.720 0.280
G12 Spinal muscular atrophy and related syndromes
0.279 0.720 0.001
E61.9 Deficiency of nutrient element, unspecified
0.000 0.722 0.278
E61.8 Deficiency of other specified nutrient elements
0.000 0.722 0.278
E61.7 Deficiency of multiple nutrient elements
0.000 0.722 0.278
E61.6 Vanadium deficiency
0.000 0.722 0.278
E61.5 Molybdenum deficiency
0.000 0.722 0.278
E61.4 Chromium deficiency
0.000 0.722 0.278
E61.3 Manganese deficiency
0.000 0.722 0.278
E61.0 Copper deficiency
0.000 0.722 0.278
L40.5 Arthropathic psoriasis
0.276 0.724 0.000
G94.2 Hydrocephalus in other diseases classified elsewhere
0.272 0.727 0.001
M06 Other rheumatoid arthritis
0.000 0.728 0.272
E53.9 Vitamin B deficiency, unspecified
0.000 0.729 0.271
G00.8 Other bacterial meningitis
0.269 0.731 0.000
G00.3 Staphylococcal meningitis
0.269 0.731 0.000
G00.0 Haemophilus meningitis
0.269 0.731 0.000
E06.5 Other chronic thyroiditis
0.000 0.732 0.268
E06.4 Drug-induced thyroiditis
0.000 0.732 0.268
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.732 0.268
E06.1 Subacute thyroiditis
0.000 0.732 0.268
E06.0 Acute thyroiditis
0.000 0.732 0.268
G50-G59 Nerve, nerve root and plexus disorders
0.267 0.733 0.000
G57 Mononeuropathies of lower limb
0.266 0.734 0.000
E55.0 Rickets, active
0.000 0.736 0.264
E53.1 Pyridoxine deficiency
0.000 0.736 0.264
E53.0 Riboflavin deficiency
0.000 0.736 0.264
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere
0.262 0.738 0.000
G02.1 Meningitis in mycoses
0.262 0.738 0.000
G00.1 Pneumococcal meningitis
0.262 0.738 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.741 0.259
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.741 0.259
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.741 0.259
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.741 0.259
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.741 0.259
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.741 0.259
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.741 0.259
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.741 0.259
G83 Other paralytic syndromes
0.257 0.743 0.000
E24 Cushing's syndrome
0.000 0.744 0.256
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.748 0.252
G57.8 Other mononeuropathies of lower limb
0.252 0.748 0.000
G82 Paraplegia and tetraplegia
0.251 0.749 0.000
E06.9 Thyroiditis, unspecified
0.000 0.750 0.250
G95.8 Other specified diseases of spinal cord
0.246 0.754 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.246 0.754 0.000
L40.3 Pustulosis palmaris et plantaris
0.245 0.754 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.755 0.244
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.755 0.244
E16.4 Abnormal secretion of gastrin
0.000 0.755 0.244
E16.3 Increased secretion of glucagon
0.000 0.755 0.244
G30.9 Alzheimer's disease, unspecified
0.238 0.762 0.000
G57.6 Lesion of plantar nerve
0.237 0.763 0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.236 0.763 0.000
E50.9 Vitamin A deficiency, unspecified
0.000 0.764 0.236
E50.8 Other manifestations of vitamin A deficiency
0.000 0.764 0.236
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.764 0.236
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.764 0.236
E50.5 Vitamin A deficiency with night blindness
0.000 0.764 0.236
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.764 0.236
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.764 0.236
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.764 0.236
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.764 0.236
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.764 0.236
E51.9 Thiamine deficiency, unspecified
0.000 0.764 0.236
E51.8 Other manifestations of thiamine deficiency
0.000 0.764 0.236
E51.2 Wernicke's encephalopathy
0.000 0.764 0.236
E51.1 Beriberi
0.000 0.764 0.236
E63.9 Nutritional deficiency, unspecified
0.000 0.764 0.236
E63.8 Other specified nutritional deficiencies
0.000 0.764 0.236
E63.1 Imbalance of constituents of food intake
0.000 0.764 0.236
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.764 0.236
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.764 0.236
E64.8 Sequelae of other nutritional deficiencies
0.000 0.764 0.236
E64.3 Sequelae of rickets
0.000 0.764 0.236
E64.2 Sequelae of vitamin C deficiency
0.000 0.764 0.236
E64.1 Sequelae of vitamin A deficiency
0.000 0.764 0.236
E64.0 Sequelae of protein-energy malnutrition
0.000 0.764 0.236
E21.3 Hyperparathyroidism, unspecified
0.000 0.767 0.233
E22 Hyperfunction of pituitary gland
0.000 0.771 0.229
E56.9 Vitamin deficiency, unspecified
0.000 0.772 0.227
E56.8 Deficiency of other vitamins
0.000 0.772 0.227
E56.0 Deficiency of vitamin E
0.000 0.772 0.227
E61.2 Magnesium deficiency
0.000 0.773 0.227
G44.3 Chronic posttraumatic headache
0.225 0.775 0.000
L40.8 Other psoriasis
0.225 0.775 0.000
G82.1 Spastic paraplegia
0.222 0.778 0.000
E24.9 Cushing's syndrome, unspecified
0.000 0.778 0.222
G44.1 Vascular headache, not elsewhere classified
0.221 0.779 0.000
G60.8 Other hereditary and idiopathic neuropathies
0.221 0.779 0.000
G44.4 Drug-induced headache, not elsewhere classified
0.220 0.780 0.000
E28 Ovarian dysfunction
0.000 0.782 0.218
G44.2 Tension-type headache
0.217 0.783 0.000
G57.1 Meralgia paraesthetica
0.217 0.783 0.000
E56.1 Deficiency of vitamin K
0.000 0.784 0.216
G95.1 Vascular myelopathies
0.215 0.784 0.000
L40.4 Guttate psoriasis
0.214 0.786 0.000
L40.2 Acrodermatitis continua
0.214 0.786 0.000
L40.1 Generalised pustular psoriasis
0.214 0.786 0.000
G57.5 Tarsal tunnel syndrome
0.212 0.788 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.788 0.212
G60.0 Hereditary motor and sensory neuropathy
0.209 0.790 0.000
G57.0 Lesion of sciatic nerve
0.209 0.791 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.793 0.207
E32 Diseases of thymus
0.000 0.793 0.207
E31 Polyglandular dysfunction
0.000 0.793 0.207
E30 Disorders of puberty, not elsewhere classified
0.000 0.793 0.207
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.793 0.206
E45 Retarded development following protein-energy malnutrition
0.000 0.793 0.206
E43 Unspecified severe protein-energy malnutrition
0.000 0.793 0.206
E42 Marasmic kwashiorkor
0.000 0.793 0.206
E41 Nutritional marasmus
0.000 0.793 0.206
E40 Kwashiorkor
0.000 0.793 0.206
G60.9 Hereditary and idiopathic neuropathy, unspecified
0.205 0.794 0.000
G60.3 Idiopathic progressive neuropathy
0.205 0.794 0.000
G60.2 Neuropathy in association with hereditary ataxia
0.205 0.794 0.000
G60.1 Refsum's disease
0.205 0.794 0.000
G52 Disorders of other cranial nerves
0.203 0.797 0.000
G00.9 Bacterial meningitis, unspecified
0.202 0.797 0.000
G02.0 Meningitis in viral diseases classified elsewhere
0.201 0.798 0.001
G12.9 Spinal muscular atrophy, unspecified
0.200 0.799 0.001
G12.8 Other spinal muscular atrophies and related syndromes
0.200 0.799 0.001
G12.1 Other inherited spinal muscular atrophy
0.200 0.799 0.001
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]
0.200 0.799 0.001
G90 Disorders of autonomic nervous system
0.199 0.799 0.002
G83.2 Monoplegia of upper limb
0.200 0.800 0.000
E24.2 Drug-induced Cushing's syndrome
0.000 0.801 0.199
G93.9 Disorder of brain, unspecified
0.197 0.802 0.001
M06.2 Rheumatoid bursitis
0.000 0.805 0.195
M06.1 Adult-onset Still's disease
0.000 0.805 0.195
G83.4 Cauda equina syndrome
0.194 0.806 0.000
E24.0 Pituitary-dependent Cushing's disease
0.000 0.807 0.193
G91 Hydrocephalus
0.190 0.808 0.001
G57.4 Lesion of medial popliteal nerve
0.191 0.809 0.000
G57.2 Lesion of femoral nerve
0.191 0.809 0.000
G93.0 Cerebral cysts
0.188 0.810 0.002
M06.8 Other specified rheumatoid arthritis
0.000 0.811 0.189
G70 Myasthenia gravis and other myoneural disorders
0.188 0.812 0.000
G57.9 Mononeuropathy of lower limb, unspecified
0.187 0.813 0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.186 0.814 0.000
E29 Testicular dysfunction
0.000 0.814 0.186
E65-E68 Obesity and other hyperalimentation
0.000 0.815 0.185
G83.5 Locked-in syndrome
0.184 0.815 0.000
G83.3 Monoplegia, unspecified
0.184 0.815 0.000
G83.0 Diplegia of upper limbs
0.184 0.815 0.000
G83.8 Other specified paralytic syndromes
0.184 0.816 0.000
E24.8 Other Cushing's syndrome
0.000 0.816 0.184
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.816 0.184
E24.3 Ectopic ACTH syndrome
0.000 0.816 0.184
E24.1 Nelson's syndrome
0.000 0.816 0.184
E25 Adrenogenital disorders
0.000 0.817 0.182
E21.4 Other specified disorders of parathyroid gland
0.000 0.819 0.181
E21.2 Other hyperparathyroidism
0.000 0.819 0.181
G80 Infantile cerebral palsy
0.180 0.819 0.001
G83.1 Monoplegia of lower limb
0.180 0.820 0.000
G82.3 Flaccid tetraplegia
0.180 0.820 0.000
G82.0 Flaccid paraplegia
0.180 0.820 0.000
G71 Primary disorders of muscles
0.179 0.820 0.000
E20 Hypoparathyroidism
0.000 0.821 0.179
E23 Hypofunction and other disorders of pituitary gland
0.000 0.821 0.179
G58 Other mononeuropathies
0.178 0.822 0.000
G95.9 Disease of spinal cord, unspecified
0.176 0.824 0.000
G63.8 Polyneuropathy in other diseases classified elsewhere
0.176 0.824 0.000
G63.6 Polyneuropathy in other musculoskeletal disorders
0.176 0.824 0.000
G63.5 Polyneuropathy in systemic connective tissue disorders
0.176 0.824 0.000
G63.4 Polyneuropathy in nutritional deficiency
0.176 0.824 0.000
G63.3 Polyneuropathy in other endocrine and metabolic diseases
0.176 0.824 0.000
G63.1 Polyneuropathy in neoplastic disease
0.176 0.824 0.000
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere
0.176 0.824 0.000
G57.3 Lesion of lateral popliteal nerve
0.175 0.825 0.000
E22.0 Acromegaly and pituitary gigantism
0.000 0.827 0.173
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.827 0.173
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.827 0.173
M06.4 Inflammatory polyarthropathy
0.000 0.828 0.172
E22.1 Hyperprolactinaemia
0.000 0.829 0.171
G44.8 Other specified headache syndromes
0.170 0.830 0.000
G73.7 Myopathy other diseases classified elsewhere
0.170 0.830 0.000
G73.6 Myopathy in metabolic diseases
0.170 0.830 0.000
G73.5 Myopathy in endocrine diseases
0.170 0.830 0.000
G73.4 Myopathy in infectious and parasitic diseases classified elsewhere
0.170 0.830 0.000
G73.3 Myasthenic syndromes in other diseases classified elsewhere
0.170 0.830 0.000
G73.2 Other myasthenic syndromes in neoplastic disease
0.170 0.830 0.000
G73.1 Eaton-Lambert syndrome
0.170 0.830 0.000
G73.0 Myasthenic syndromes in endocrine diseases
0.170 0.830 0.000
G43.9 Migraine, unspecified
0.169 0.831 0.000
E28.2 Polycystic ovarian syndrome
0.000 0.832 0.168
G82.4 Spastic tetraplegia
0.165 0.835 0.000
G44.0 Cluster headache syndrome
0.165 0.835 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.836 0.164
E22.8 Other hyperfunction of pituitary gland
0.000 0.836 0.164
G52.8 Disorders of other specified cranial nerves
0.162 0.838 0.000
E26 Hyperaldosteronism
0.000 0.842 0.158
G82.5 Tetraplegia, unspecified
0.157 0.843 0.000
E28.9 Ovarian dysfunction, unspecified
0.000 0.843 0.157
E28.8 Other ovarian dysfunction
0.000 0.843 0.157
E28.1 Androgen excess
0.000 0.843 0.157
E28.0 Oestrogen excess
0.000 0.843 0.157
E28.3 Primary ovarian failure
0.000 0.843 0.157
M06.3 Rheumatoid nodule
0.000 0.843 0.156
M06.0 Seronegative rheumatoid arthritis
0.000 0.845 0.155
G81 Hemiplegia
0.154 0.845 0.000
G63.2 Diabetic polyneuropathy
0.154 0.846 0.000
G83.9 Paralytic syndrome, unspecified
0.152 0.847 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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