TreeWAS – Variant ID: rs1264701

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	0.000	1.000
L40.9 Psoriasis, unspecified	0.000	1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.003	0.997
M06.9 Rheumatoid arthritis, unspecified	0.003	0.997
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.008	0.992
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.080	0.920
L40 Psoriasis	0.114	0.886
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.136	0.864
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.161	0.839
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.181	0.819
L40.5 Arthropathic psoriasis	0.185	0.815
L40.0 Psoriasis vulgaris	0.219	0.781
M06.98 Rheumatoid arthritis, unspecified (Other)	0.229	0.770
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.230	0.770
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.324	0.676
L40.8 Other psoriasis	0.330	0.670
L40.4 Guttate psoriasis	0.365	0.635
L40.2 Acrodermatitis continua	0.365	0.635
L40.1 Generalised pustular psoriasis	0.365	0.635
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.378	0.622
L40.3 Pustulosis palmaris et plantaris	0.415	0.585
K90 Intestinal malabsorption	0.486	0.514
E10 Insulin-dependent diabetes mellitus	0.506	0.494
E10.9 Without complications	0.508	0.492
E10-E14 Diabetes mellitus	0.512	0.488
E11 Non-insulin-dependent diabetes mellitus	0.514	0.486
M06 Other rheumatoid arthritis	0.516	0.484
E11.3 With ophthalmic complications	0.528	0.472
E11.5 With peripheral circulatory complications	0.557	0.443
E10.3 With ophthalmic complications	0.567	0.433
E11.0 With coma	0.572	0.428
K90.8 Other intestinal malabsorption	0.580	0.420
M06.0 Seronegative rheumatoid arthritis	0.587	0.413
E10.0 With coma	0.589	0.411
E13 Other specified diabetes mellitus	0.602	0.398
E53.8 Deficiency of other specified B group vitamins	0.608	0.392
E10.5 With peripheral circulatory complications	0.614	0.386
E11.1 With ketoacidosis	0.614	0.386
E11.4 With neurological complications	0.619	0.381
E10.1 With ketoacidosis	0.629	0.371
K90.3 Pancreatic steatorrhoea	0.631	0.368
K90.2 Blind loop syndrome, not elsewhere classified	0.631	0.368
K90.1 Tropical sprue	0.631	0.368
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.638	0.362
E10.8 With unspecified complications	0.638	0.362
E10.6 With other specified complications	0.640	0.360
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.643	0.357
E11.8 With unspecified complications	0.645	0.355
E10.7 With multiple complications	0.646	0.354
K90.9 Intestinal malabsorption, unspecified	0.649	0.351
E12 Malnutrition-related diabetes mellitus	0.650	0.350
E11.7 With multiple complications	0.651	0.348
E53 Deficiency of other B group vitamins	0.652	0.348
M06.8 Other specified rheumatoid arthritis	0.653	0.347
M06.2 Rheumatoid bursitis	0.653	0.347
M06.1 Adult-onset Still's disease	0.653	0.347
E13.9 Without complications	0.666	0.334
E11.6 With other specified complications	0.672	0.328
E50-E64 Other nutritional deficiencies	0.673	0.327
E10.4 With neurological complications	0.675	0.325
Chapter IV Endocrine, nutritional and metabolic diseases	0.679	0.321
E11.2 With renal complications	0.680	0.320
M06.4 Inflammatory polyarthropathy	0.688	0.312
E14 Unspecified diabetes mellitus	0.689	0.311
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.696	0.304
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.701	0.299
M06.08 Seronegative rheumatoid arthritis (Other)	0.704	0.296
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.704	0.296
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.704	0.296
M06.04 Seronegative rheumatoid arthritis (Hand)	0.704	0.296
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.704	0.296
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.704	0.296
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.704	0.296
E10.2 With renal complications	0.708	0.292
E13.8 With unspecified complications	0.714	0.286
E13.7 With multiple complications	0.714	0.286
E13.6 With other specified complications	0.714	0.286
E13.5 With peripheral circulatory complications	0.714	0.286
E13.4 With neurological complications	0.714	0.286
E13.3 With ophthalmic complications	0.714	0.286
E13.2 With renal complications	0.714	0.286
E13.1 With ketoacidosis	0.714	0.286
E13.0 With coma	0.714	0.286
E14.3 With ophthalmic complications	0.721	0.279
M06.3 Rheumatoid nodule	0.730	0.270
E12.9 Without complications	0.749	0.251
E12.8 With unspecified complications	0.749	0.251
E12.7 With multiple complications	0.749	0.251
E12.6 With other specified complications	0.749	0.251
E12.5 With peripheral circulatory complications	0.749	0.251
E12.4 With neurological complications	0.749	0.251
E12.3 With ophthalmic complications	0.749	0.251
E12.2 With renal complications	0.749	0.251
E12.1 With ketoacidosis	0.749	0.251
E12.0 With coma	0.749	0.251
E53.1 Pyridoxine deficiency	0.750	0.250
E53.0 Riboflavin deficiency	0.750	0.250
M06.19 Adult-onset Still's disease (Site unspecified)	0.751	0.249
M06.18 Adult-onset Still's disease (Other)	0.751	0.249
M06.17 Adult-onset Still's disease (Ankle and foot)	0.751	0.249
M06.16 Adult-onset Still's disease (Lower leg)	0.751	0.249
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.751	0.249
M06.14 Adult-onset Still's disease (Hand)	0.751	0.249
M06.13 Adult-onset Still's disease (Forearm)	0.751	0.249
M06.12 Adult-onset Still's disease (Upper arm)	0.751	0.249
M06.11 Adult-onset Still's disease (Shoulder region)	0.751	0.249
M06.10 Adult-onset Still's disease (Multiple sites)	0.751	0.249
M06.29 Rheumatoid bursitis (Site unspecified)	0.751	0.249
M06.28 Rheumatoid bursitis (Other)	0.751	0.249
M06.27 Rheumatoid bursitis (Ankle and foot)	0.751	0.249
M06.26 Rheumatoid bursitis (Lower leg)	0.751	0.249
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.751	0.249
M06.24 Rheumatoid bursitis (Hand)	0.751	0.249
M06.23 Rheumatoid bursitis (Forearm)	0.751	0.249
M06.22 Rheumatoid bursitis (Upper arm)	0.751	0.249
M06.21 Rheumatoid bursitis (Shoulder region)	0.751	0.249
M06.20 Rheumatoid bursitis (Multiple sites)	0.751	0.249
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.751	0.249
M06.88 Other specified rheumatoid arthritis (Other)	0.751	0.249
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.751	0.249
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.751	0.249
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.751	0.249
M06.84 Other specified rheumatoid arthritis (Hand)	0.751	0.249
M06.83 Other specified rheumatoid arthritis (Forearm)	0.751	0.249
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.751	0.249
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.751	0.249
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.751	0.249
E61 Deficiency of other nutrient elements	0.757	0.243
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.761	0.238
E14.4 With neurological complications	0.762	0.238
E64 Sequelae of malnutrition and other nutritional deficiencies	0.765	0.235
E63 Other nutritional deficiencies	0.765	0.235
E56 Other vitamin deficiencies	0.765	0.235
E50 Vitamin A deficiency	0.765	0.235
E60 Dietary zinc deficiency	0.765	0.235
E59 Dietary selenium deficiency	0.765	0.235
E54 Ascorbic acid deficiency	0.765	0.235
E52 Niacin deficiency [pellagra]	0.765	0.235
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.768	0.232
E14.1 With ketoacidosis	0.771	0.229
E51 Thiamine deficiency	0.773	0.227
M06.48 Inflammatory polyarthropathy (Other)	0.776	0.224
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.776	0.224
M06.46 Inflammatory polyarthropathy (Lower leg)	0.776	0.224
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.776	0.224
M06.44 Inflammatory polyarthropathy (Hand)	0.776	0.224
M06.43 Inflammatory polyarthropathy (Forearm)	0.776	0.224
M06.42 Inflammatory polyarthropathy (Upper arm)	0.776	0.224
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.776	0.224
E14.7 With multiple complications	0.777	0.223
E14.5 With peripheral circulatory complications	0.777	0.223
E14.0 With coma	0.777	0.223
E14.6 With other specified complications	0.778	0.222
E14.8 With unspecified complications	0.785	0.215
E40-E46 Malnutrition	0.786	0.214
L40-L45 Papulosquamous disorders	0.788	0.212
E58 Dietary calcium deficiency	0.790	0.210
E53.9 Vitamin B deficiency, unspecified	0.799	0.200
M06.39 Rheumatoid nodule (Site unspecified)	0.806	0.194
M06.38 Rheumatoid nodule (Other)	0.806	0.194
M06.36 Rheumatoid nodule (Lower leg)	0.806	0.194
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.806	0.194
M06.33 Rheumatoid nodule (Forearm)	0.806	0.194
M06.31 Rheumatoid nodule (Shoulder region)	0.806	0.194
M06.30 Rheumatoid nodule (Multiple sites)	0.806	0.194
M06.32 Rheumatoid nodule (Upper arm)	0.807	0.193
E61.1 Iron deficiency	0.810	0.190
E55 Vitamin D deficiency	0.815	0.185
E14.2 Withrenal complications	0.817	0.183
E65-E68 Obesity and other hyperalimentation	0.818	0.182
E61.9 Deficiency of nutrient element, unspecified	0.825	0.175
E61.8 Deficiency of other specified nutrient elements	0.825	0.175
E61.7 Deficiency of multiple nutrient elements	0.825	0.175
E61.6 Vanadium deficiency	0.825	0.175
E61.5 Molybdenum deficiency	0.825	0.175
E61.4 Chromium deficiency	0.825	0.175
E61.3 Manganese deficiency	0.825	0.175
E61.0 Copper deficiency	0.825	0.175
M06.37 Rheumatoid nodule (Ankle and foot)	0.829	0.171
E50.9 Vitamin A deficiency, unspecified	0.831	0.168
E50.8 Other manifestations of vitamin A deficiency	0.831	0.168
E50.7 Other ocular manifestations of vitamin A deficiency	0.831	0.168
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.831	0.168
E50.5 Vitamin A deficiency with night blindness	0.831	0.168
E50.4 Vitamin A deficiency with keratomalacia	0.831	0.168
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.831	0.168
E50.2 Vitamin A deficiency with corneal xerosis	0.831	0.168
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.831	0.168
E50.0 Vitamin A deficiency with conjunctival xerosis	0.831	0.168
E56.9 Vitamin deficiency, unspecified	0.831	0.168
E56.8 Deficiency of other vitamins	0.831	0.168
E56.1 Deficiency of vitamin K	0.831	0.168
E56.0 Deficiency of vitamin E	0.831	0.168
E63.9 Nutritional deficiency, unspecified	0.831	0.168
E63.8 Other specified nutritional deficiencies	0.831	0.168
E63.1 Imbalance of constituents of food intake	0.831	0.168
E63.0 Essential fatty acid [EFA] deficiency	0.831	0.168
E64.9 Sequelae of unspecified nutritional deficiency	0.831	0.168
E64.8 Sequelae of other nutritional deficiencies	0.831	0.168
E64.3 Sequelae of rickets	0.831	0.168
E64.2 Sequelae of vitamin C deficiency	0.831	0.168
E64.1 Sequelae of vitamin A deficiency	0.831	0.168
E64.0 Sequelae of protein-energy malnutrition	0.831	0.168
E16 Other disorders of pancreatic internal secretion	0.833	0.167
E15 Nondiabetic hypoglycaemic coma	0.834	0.166
E61.2 Magnesium deficiency	0.834	0.166
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.835	0.164
E51.9 Thiamine deficiency, unspecified	0.837	0.163
E51.8 Other manifestations of thiamine deficiency	0.837	0.163
E51.1 Beriberi	0.837	0.163
E00-E07 Disorders of thyroid gland	0.841	0.159
E51.2 Wernicke's encephalopathy	0.845	0.155
M06.34 Rheumatoid nodule (Hand)	0.846	0.154
E44 Protein-energy malnutrition of moderate and mild degree	0.846	0.153
E45 Retarded development following protein-energy malnutrition	0.846	0.153
E43 Unspecified severe protein-energy malnutrition	0.846	0.153
E42 Marasmic kwashiorkor	0.846	0.153
E41 Nutritional marasmus	0.846	0.153
E40 Kwashiorkor	0.846	0.153
L44 Other papulosquamous disorders	0.848	0.152
L41 Parapsoriasis	0.848	0.152
L45 Papulosquamous disorders in diseases classified elsewhere	0.848	0.152
O34.2 Maternal care due to uterine scar from previous surgery	0.850	0.150
E65 Localised adiposity	0.855	0.145
E16.0 Drug-induced hypoglycaemia without coma	0.856	0.143
E11.9 Without complications	0.857	0.143
L42 Pityriasis rosea	0.859	0.140
E04 Other non-toxic goitre	0.860	0.140
E46 Unspecified protein-energy malnutrition	0.863	0.137
E04.2 Non-toxic multinodular goitre	0.863	0.137
E55.0 Rickets, active	0.867	0.133
E67 Other hyperalimentation	0.869	0.130
E68 Sequelae of hyperalimentation	0.869	0.130
E20-E35 Disorders of other endocrine glands	0.872	0.128
E07 Other disorders of thyroid	0.874	0.125
E16.1 Other hypoglycaemia	0.878	0.122
M05-M14 Inflammatory polyarthropathies	0.880	0.120
E16.9 Disorder of pancreatic internal secretion, unspecified	0.880	0.120
E16.8 Other specified disorders of pancreatic internal secretion	0.880	0.120
E16.4 Abnormal secretion of gastrin	0.880	0.120
E16.3 Increased secretion of glucagon	0.880	0.120
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.886	0.114
E00 Congenital iodine-deficiency syndrome	0.886	0.114
E03 Other hypothyroidism	0.889	0.111
E04.0 Non-toxic diffuse goitre	0.890	0.110
E44.1 Mild protein-energy malnutrition	0.890	0.110
E44.0 Moderate protein-energy malnutrition	0.890	0.110
L41.9 Parapsoriasis, unspecified	0.891	0.109
L41.8 Other parapsoriasis	0.891	0.109
L41.5 Retiform parapsoriasis	0.891	0.109
L41.4 Large plaque parapsoriasis	0.891	0.109
L41.3 Small plaque parapsoriasis	0.891	0.109
L41.2 Lymphomatoid papulosis	0.891	0.109
L41.1 Pityriasis lichenoides chronica	0.891	0.109
L41.0 Pityriasis lichenoides et varioliformis acuta	0.891	0.109
L44.9 Papulosquamous disorder, unspecified	0.891	0.109
L44.8 Other specified papulosquamous disorders	0.891	0.109
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.891	0.109
L44.3 Lichen ruber moniliformis	0.891	0.109
L44.2 Lichen striatus	0.891	0.109
L44.1 Lichen nitidus	0.891	0.109
L44.0 Pityriasis rubra pilaris	0.891	0.109
E28 Ovarian dysfunction	0.892	0.108
E27 Other disorders of adrenal gland	0.894	0.106
E02 Subclinical iodine-deficiency hypothyroidism	0.897	0.103
E07.8 Other specified disorders of thyroid	0.897	0.103
M05 Seropositive rheumatoid arthritis	0.899	0.101
E27.1 Primary adrenocortical insufficiency	0.899	0.101
E04.8 Other specified non-toxic goitre	0.899	0.100
M07 Psoriatic and enteropathic arthropathies	0.901	0.098
E24 Cushing's syndrome	0.904	0.096
L43 Lichen planus	0.905	0.094
E67.8 Other specified hyperalimentation	0.906	0.094
E67.3 Hypervitaminosis D	0.906	0.094
E67.2 Megavitamin-B6 syndrome	0.906	0.094
E67.1 Hypercarotenaemia	0.906	0.094
E67.0 Hypervitaminosis A	0.906	0.094
M05.9 Seropositive rheumatoid arthritis, unspecified	0.908	0.092
E35 Disorders of endocrine glands in diseases classified elsewhere	0.908	0.092
E32 Diseases of thymus	0.908	0.092
E31 Polyglandular dysfunction	0.908	0.092
E30 Disorders of puberty, not elsewhere classified	0.908	0.092
E25 Adrenogenital disorders	0.908	0.092
E20 Hypoparathyroidism	0.910	0.090
E07.1 Dyshormogenetic goitre	0.910	0.090
E07.0 Hypersecretion of calcitonin	0.910	0.090
E28.3 Primary ovarian failure	0.910	0.090
E07.9 Disorder of thyroid, unspecified	0.912	0.088
E26 Hyperaldosteronism	0.913	0.087
M09 Juvenile arthritis in diseases classified elsewhere	0.913	0.086
M08 Juvenile arthritis	0.913	0.086
E03.9 Hypothyroidism, unspecified	0.913	0.087
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.914	0.086
E28.2 Polycystic ovarian syndrome	0.916	0.084
M12 Other specific arthropathies	0.916	0.084
M14 Arthropathies in other diseases classified elsewhere	0.916	0.084
M07.3 Other psoriatic arthropathies	0.917	0.083
E27.9 Disorder of adrenal gland, unspecified	0.917	0.082
E55.9 Vitamin D deficiency, unspecified	0.918	0.082
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.918	0.082
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.918	0.082
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.918	0.082
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.918	0.082
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.918	0.082
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.918	0.082
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.918	0.082
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.918	0.082
E03.8 Other specified hypothyroidism	0.919	0.081
E03.5 Myxoedema coma	0.920	0.080
E03.4 Atrophy of thyroid (acquired)	0.920	0.080
E03.3 Postinfectious hypothyroidism	0.920	0.080
E03.0 Congenital hypothyroidism with diffuse goitre	0.920	0.080
E23 Hypofunction and other disorders of pituitary gland	0.920	0.080
E27.4 Other and unspecified adrenocortical insufficiency	0.920	0.080
M07.39 Other psoriatic arthropathies (Site unspecified)	0.921	0.079
E34 Other endocrine disorders	0.922	0.078
E28.9 Ovarian dysfunction, unspecified	0.922	0.077
E28.8 Other ovarian dysfunction	0.922	0.077
E28.1 Androgen excess	0.922	0.077
E28.0 Oestrogen excess	0.922	0.077
E27.5 Adrenomedullary hyperfunction	0.923	0.076
E27.0 Other adrenocortical overactivity	0.923	0.076
E03.1 Congenital hypothyroidism without goitre	0.924	0.076
M10 Gout	0.925	0.075
E16.2 Hypoglycaemia, unspecified	0.926	0.073
M05.8 Other seropositive rheumatoid arthritis	0.927	0.073
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.927	0.073
M05.1 Rheumatoid lung disease	0.927	0.073
M05.0 Felty's syndrome	0.927	0.073
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.927	0.073
E24.9 Cushing's syndrome, unspecified	0.928	0.072
M07.6 Other enteropathic arthropathies	0.929	0.071
M07.5 Arthropathy in ulcerative colitis	0.929	0.071
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.929	0.071
M07.2 Psoriatic spondylitis	0.929	0.071
M07.1 Arthritis mutilans	0.929	0.071
M07.0 Distal interphalangeal psoriatic arthropathy	0.929	0.071
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.929	0.071
E24.2 Drug-induced Cushing's syndrome	0.930	0.070
E27.2 Addisonian crisis	0.931	0.069
E24.8 Other Cushing's syndrome	0.931	0.069
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.931	0.069
E24.3 Ectopic ACTH syndrome	0.931	0.069
E24.1 Nelson's syndrome	0.931	0.069
E24.0 Pituitary-dependent Cushing's disease	0.931	0.069
L43.3 Subacute (active) lichen planus	0.932	0.068
L43.2 Lichenoid drug reaction	0.932	0.068
L43.1 Bullous lichen planus	0.932	0.068
L43.0 Hypertrophic lichen planus	0.932	0.068
E29 Testicular dysfunction	0.933	0.066
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.934	0.066
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.934	0.066
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.934	0.066
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.934	0.066
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.934	0.066
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.934	0.066
M11 Other crystal arthropathies	0.934	0.066
E23.7 Disorder of pituitary gland, unspecified	0.934	0.066
E25.9 Adrenogenital disorder, unspecified	0.934	0.066
E25.8 Other adrenogenital disorders	0.934	0.066
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.934	0.066
E30.9 Disorder of puberty, unspecified	0.934	0.066
E30.8 Other disorders of puberty	0.934	0.066
E30.1 Precocious puberty	0.934	0.066
E30.0 Delayed puberty	0.934	0.066
E31.9 Polyglandular dysfunction, unspecified	0.934	0.066
E31.8 Other polyglandular dysfunction	0.934	0.066
E31.1 Polyglandular hyperfunction	0.934	0.066
E31.0 Autoimmune polyglandular failure	0.934	0.066
E32.9 Disease of thymus, unspecified	0.934	0.066
E32.8 Other diseases of thymus	0.934	0.066
E32.1 Abscess of thymus	0.934	0.066
E32.0 Persistent hyperplasia of thymus	0.934	0.066
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.934	0.066
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.934	0.066
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.934	0.066
E20.8 Other hypoparathyroidism	0.935	0.065
E20.1 Pseudohypoparathyroidism	0.935	0.065
E20.0 Idiopathic hypoparathyroidism	0.935	0.065
M07.36 Other psoriatic arthropathies (Lower leg)	0.936	0.064
E20.9 Hypoparathyroidism, unspecified	0.936	0.063
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.937	0.063
E22 Hyperfunction of pituitary gland	0.937	0.063
E26.9 Hyperaldosteronism, unspecified	0.937	0.063
E26.8 Other hyperaldosteronism	0.937	0.063
E26.1 Secondary hyperaldosteronism	0.937	0.063
M08.9 Juvenile arthritis, unspecified	0.938	0.062
M08.8 Other juvenile arthritis	0.938	0.062
M08.4 Pauciarticular juvenile arthritis	0.938	0.062
M08.3 Juvenile polyarthritis (seronegative)	0.938	0.062
M08.2 Juvenile arthritis with systemic onset	0.938	0.062
M08.1 Juvenile ankylosing spondylitis	0.938	0.062
M08.0 Juvenile rheumatoid arthritis	0.938	0.062
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.938	0.062
M09.2 Juvenile arthritis in ulcerative colitis	0.938	0.062
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.938	0.062
M09.0 Juvenile arthritis in psoriasis	0.938	0.062
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.939	0.061
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.939	0.061
E23.2 Diabetes insipidus	0.939	0.061
E27.3 Drug-induced adrenocortical insufficiency	0.939	0.060
M12.8 Other specific arthropathies, not elsewhere classified	0.940	0.060
M12.5 Traumatic arthropathy	0.940	0.060
M12.4 Intermittent hydrarthrosis	0.940	0.060
M12.1 Kaschin-Beck disease	0.940	0.060
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.940	0.060
M05.2 Rheumatoid vasculitis	0.940	0.060
M14.8 Arthropathies in other specified diseases classified elsewhere	0.940	0.060
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.940	0.060
M14.4 Arthropathy in amyloidosis	0.940	0.060
M14.3 Lipoid dermatoarthritis	0.940	0.060
M14.2 Diabetic arthropathy	0.940	0.060
M14.1 Crystal arthropathy in other metabolic disorders	0.940	0.060
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.940	0.060
L43.8 Other lichen planus	0.940	0.060
M07.38 Other psoriatic arthropathies (Other)	0.940	0.060
M07.33 Other psoriatic arthropathies (Forearm)	0.940	0.060
M07.32 Other psoriatic arthropathies (Upper arm)	0.940	0.060
M07.31 Other psoriatic arthropathies (Shoulder region)	0.940	0.060
E04.9 Non-toxic goitre, unspecified	0.940	0.059
M12.2 Villonodular synovitis (pigmented)	0.941	0.059
E04.1 Non-toxic single thyroid nodule	0.941	0.059
M12.3 Palindromic rheumatism	0.941	0.059
E34.0 Carcinoid syndrome	0.941	0.059
M10.0 Idiopathic gout	0.941	0.058
E26.0 Primary hyperaldosteronism	0.942	0.058
M14.6 Neuropathic arthropathy	0.942	0.057
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.942	0.057
E23.1 Drug-induced hypopituitarism	0.942	0.057
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.943	0.057
E23.6 Other disorders of pituitary gland	0.943	0.056
E34.9 Endocrine disorder, unspecified	0.943	0.056
O34 Maternal care for known or suspected abnormality of pelvic organs	0.944	0.056
E34.5 Androgen resistance syndrome	0.944	0.056
E34.4 Constitutional tall stature	0.944	0.056
E34.2 Ectopic hormone secretion, not elsewhere classified	0.944	0.056
E34.1 Other hypersecretion of intestinal hormones	0.944	0.056
M07.34 Other psoriatic arthropathies (Hand)	0.945	0.055
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.946	0.054
M10.4 Other secondary gout	0.946	0.054
M10.3 Gout due to impairment of renal function	0.946	0.054
M10.2 Drug-induced gout	0.946	0.054
M10.1 Lead-induced gout	0.946	0.054
M05.09 Felty's syndrome (Site unspecified)	0.947	0.052
M05.08 Felty's syndrome (Other)	0.947	0.052
M05.07 Felty's syndrome (Ankle and foot)	0.947	0.052
M05.06 Felty's syndrome (Lower leg)	0.947	0.052
M05.05 Felty's syndrome (Pelvic region and thigh)	0.947	0.052
M05.04 Felty's syndrome (Hand)	0.947	0.052
M05.03 Felty's syndrome (Forearm)	0.947	0.052
M05.02 Felty's syndrome (Upper arm)	0.947	0.052
M05.01 Felty's syndrome (Shoulder region)	0.947	0.052
M05.00 Felty's syndrome (Multiple sites)	0.947	0.052
M05.19 Rheumatoid lung disease (Site unspecified)	0.947	0.052
M05.18 Rheumatoid lung disease (Other)	0.947	0.052
M05.17 Rheumatoid lung disease (Ankle and foot)	0.947	0.052
M05.16 Rheumatoid lung disease (Lower leg)	0.947	0.052
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.947	0.052
M05.14 Rheumatoid lung disease (Hand)	0.947	0.052
M05.13 Rheumatoid lung disease (Forearm)	0.947	0.052
M05.12 Rheumatoid lung disease (Upper arm)	0.947	0.052
M05.11 Rheumatoid lung disease (Shoulder region)	0.947	0.052
M05.10 Rheumatoid lung disease (Multiple sites)	0.947	0.052
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.947	0.052
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.947	0.052
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.947	0.052
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.947	0.052
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.947	0.052
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.947	0.052
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.947	0.052
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.947	0.052
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.947	0.052
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.947	0.052
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.947	0.052
M05.88 Other seropositive rheumatoid arthritis (Other)	0.947	0.052
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.947	0.052
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.947	0.052
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.947	0.052
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.947	0.052
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.947	0.052
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.947	0.052
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.947	0.052
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.947	0.052
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.949	0.051
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.949	0.051
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.949	0.051
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.949	0.051
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.949	0.051
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.949	0.051
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.949	0.051
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm	0.949	0.051
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region	0.949	0.051
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)	0.949	0.051
M07.19 Arthritis mutilans (Site unspecified)	0.949	0.051
M07.18 Arthritis mutilans (Other)	0.949	0.051
M07.17 Arthritis mutilans (Ankle and foot)	0.949	0.051
M07.16 Arthritis mutilans (Lower leg)	0.949	0.051
M07.15 Arthritis mutilans (Pelvic region and thigh)	0.949	0.051
M07.14 Arthritis mutilans (Hand)	0.949	0.051
M07.13 Arthritis mutilans (Forearm)	0.949	0.051

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations