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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1265053
log Bayes Factor = 138.53
Chromosome 6   position 31,079,889  (GRCh37) Explore rs1265053 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
L40 Psoriasis
0.998 0.002 0.000
E07 Other disorders of thyroid
0.000 0.003 0.997
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.004 0.996
E07.9 Disorder of thyroid, unspecified
0.000 0.005 0.995
L40.5 Arthropathic psoriasis
0.984 0.016 0.000
L40.0 Psoriasis vulgaris
0.983 0.017 0.000
E83.1 Disorders of iron metabolism
0.959 0.041 0.000
C61 Malignant neoplasm of prostate
0.869 0.131 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.149 0.851
L40.4 Guttate psoriasis
0.816 0.184 0.000
E03.8 Other specified hypothyroidism
0.000 0.192 0.808
L40.3 Pustulosis palmaris et plantaris
0.789 0.211 0.000
K90 Intestinal malabsorption
0.000 0.218 0.782
E06 Thyroiditis
0.000 0.226 0.774
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.241 0.759
L40.1 Generalised pustular psoriasis
0.736 0.264 0.000
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E10.9 Without complications
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.716 0.284 0.000
E07.1 Dyshormogenetic goitre
0.000 0.285 0.715
E07.0 Hypersecretion of calcitonin
0.000 0.285 0.715
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.288 0.712
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.289 0.711
E10 Insulin-dependent diabetes mellitus
0.000 0.295 0.705
E07.8 Other specified disorders of thyroid
0.000 0.295 0.705
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.304 0.696
E10-E14 Diabetes mellitus
0.000 0.318 0.682
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.319 0.681
E10.3 With ophthalmic complications
0.000 0.324 0.676
E06.3 Autoimmune thyroiditis
0.000 0.348 0.652
L40.8 Other psoriasis
0.644 0.356 0.000
E05.8 Other thyrotoxicosis
0.000 0.366 0.634
E06.5 Other chronic thyroiditis
0.000 0.379 0.621
K90.9 Intestinal malabsorption, unspecified
0.000 0.388 0.612
E10.2 With renal complications
0.000 0.392 0.608
E03.1 Congenital hypothyroidism without goitre
0.000 0.397 0.602
K90.8 Other intestinal malabsorption
0.000 0.410 0.590
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.413 0.587
K90.3 Pancreatic steatorrhoea
0.000 0.439 0.560
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.439 0.560
K90.1 Tropical sprue
0.000 0.439 0.560
E06.4 Drug-induced thyroiditis
0.000 0.445 0.555
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.445 0.555
E06.0 Acute thyroiditis
0.000 0.445 0.555
E06.1 Subacute thyroiditis
0.000 0.459 0.540
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E10.4 With neurological complications
0.000 0.488 0.512
E10.7 With multiple complications
0.000 0.491 0.509
E14 Unspecified diabetes mellitus
0.000 0.493 0.507
E20-E35 Disorders of other endocrine glands
0.000 0.503 0.497
E10.0 With coma
0.000 0.504 0.496
E12 Malnutrition-related diabetes mellitus
0.000 0.511 0.489
E40-E46 Malnutrition
0.000 0.527 0.473
E28 Ovarian dysfunction
0.000 0.536 0.464
E14.3 With ophthalmic complications
0.000 0.542 0.458
M35.0 Sicca syndrome [Sjogren]
0.000 0.543 0.457
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.565 0.435
E10.8 With unspecified complications
0.000 0.570 0.430
E23 Hypofunction and other disorders of pituitary gland
0.000 0.575 0.425
E28.3 Primary ovarian failure
0.000 0.576 0.424
E24 Cushing's syndrome
0.000 0.578 0.422
E10.6 With other specified complications
0.000 0.580 0.420
E13 Other specified diabetes mellitus
0.000 0.582 0.418
E14.5 With peripheral circulatory complications
0.000 0.597 0.403
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.603 0.397
E23.2 Diabetes insipidus
0.000 0.611 0.389
E10.1 With ketoacidosis
0.000 0.614 0.386
E28.2 Polycystic ovarian syndrome
0.000 0.615 0.385
E06.9 Thyroiditis, unspecified
0.000 0.621 0.378
E24.2 Drug-induced Cushing's syndrome
0.000 0.625 0.375
E14.1 With ketoacidosis
0.000 0.627 0.373
E14.8 With unspecified complications
0.000 0.627 0.373
E14.7 With multiple complications
0.000 0.636 0.364
E14.0 With coma
0.000 0.636 0.364
E21.3 Hyperparathyroidism, unspecified
0.000 0.637 0.363
E31 Polyglandular dysfunction
0.000 0.640 0.360
E14.6 With other specified complications
0.000 0.640 0.360
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.644 0.356
E32 Diseases of thymus
0.000 0.644 0.356
E30 Disorders of puberty, not elsewhere classified
0.000 0.644 0.356
E12.9 Without complications
0.000 0.649 0.350
E12.8 With unspecified complications
0.000 0.649 0.350
E12.7 With multiple complications
0.000 0.649 0.350
E12.6 With other specified complications
0.000 0.649 0.350
E12.5 With peripheral circulatory complications
0.000 0.649 0.350
E12.4 With neurological complications
0.000 0.649 0.350
E12.3 With ophthalmic complications
0.000 0.649 0.350
E12.2 With renal complications
0.000 0.649 0.350
E12.1 With ketoacidosis
0.000 0.649 0.350
E12.0 With coma
0.000 0.649 0.350
E14.2 Withrenal complications
0.000 0.651 0.349
E10.5 With peripheral circulatory complications
0.000 0.655 0.345
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.660 0.339
E45 Retarded development following protein-energy malnutrition
0.000 0.660 0.339
E43 Unspecified severe protein-energy malnutrition
0.000 0.660 0.339
E42 Marasmic kwashiorkor
0.000 0.660 0.339
E41 Nutritional marasmus
0.000 0.660 0.339
E40 Kwashiorkor
0.000 0.660 0.339
E14.4 With neurological complications
0.000 0.663 0.337
E20 Hypoparathyroidism
0.000 0.664 0.336
E28.9 Ovarian dysfunction, unspecified
0.000 0.667 0.333
E28.8 Other ovarian dysfunction
0.000 0.667 0.333
E28.1 Androgen excess
0.000 0.667 0.333
E28.0 Oestrogen excess
0.000 0.667 0.333
E23.7 Disorder of pituitary gland, unspecified
0.000 0.667 0.333
E23.6 Other disorders of pituitary gland
0.000 0.667 0.333
E26 Hyperaldosteronism
0.000 0.671 0.329
E13.3 With ophthalmic complications
0.000 0.674 0.325
E46 Unspecified protein-energy malnutrition
0.000 0.675 0.324
E15 Nondiabetic hypoglycaemic coma
0.000 0.688 0.312
E25 Adrenogenital disorders
0.000 0.689 0.310
E24.0 Pituitary-dependent Cushing's disease
0.000 0.690 0.310
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.695 0.305
E23.1 Drug-induced hypopituitarism
0.000 0.695 0.305
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.698 0.302
E24.3 Ectopic ACTH syndrome
0.000 0.698 0.302
E24.1 Nelson's syndrome
0.000 0.698 0.302
E13.8 With unspecified complications
0.000 0.700 0.300
E13.7 With multiple complications
0.000 0.700 0.300
E13.6 With other specified complications
0.000 0.700 0.300
E13.5 With peripheral circulatory complications
0.000 0.700 0.300
E13.4 With neurological complications
0.000 0.700 0.300
E13.2 With renal complications
0.000 0.700 0.300
E13.1 With ketoacidosis
0.000 0.700 0.300
E13.0 With coma
0.000 0.700 0.300
E50-E64 Other nutritional deficiencies
0.000 0.703 0.297
C60-C63 Malignant neoplasms of male genital organs
0.297 0.703 0.000
E24.8 Other Cushing's syndrome
0.000 0.704 0.296
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.704 0.296
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.705 0.295
E21.2 Other hyperparathyroidism
0.000 0.712 0.287
E29 Testicular dysfunction
0.000 0.713 0.287
E24.9 Cushing's syndrome, unspecified
0.000 0.720 0.280
L40-L45 Papulosquamous disorders
0.269 0.731 0.000
E21.4 Other specified disorders of parathyroid gland
0.000 0.734 0.266
E31.0 Autoimmune polyglandular failure
0.000 0.738 0.262
E16 Other disorders of pancreatic internal secretion
0.000 0.741 0.259
E31.9 Polyglandular dysfunction, unspecified
0.000 0.742 0.258
E31.8 Other polyglandular dysfunction
0.000 0.742 0.258
E31.1 Polyglandular hyperfunction
0.000 0.742 0.258
E30.9 Disorder of puberty, unspecified
0.000 0.744 0.255
E30.8 Other disorders of puberty
0.000 0.744 0.255
E30.1 Precocious puberty
0.000 0.744 0.255
E30.0 Delayed puberty
0.000 0.744 0.255
E32.9 Disease of thymus, unspecified
0.000 0.744 0.255
E32.8 Other diseases of thymus
0.000 0.744 0.255
E32.1 Abscess of thymus
0.000 0.744 0.255
E32.0 Persistent hyperplasia of thymus
0.000 0.744 0.255
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.744 0.255
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.744 0.255
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.744 0.255
E34 Other endocrine disorders
0.000 0.753 0.246
E44.1 Mild protein-energy malnutrition
0.000 0.756 0.243
E44.0 Moderate protein-energy malnutrition
0.000 0.756 0.243
E20.8 Other hypoparathyroidism
0.000 0.759 0.241
E20.1 Pseudohypoparathyroidism
0.000 0.759 0.241
E20.0 Idiopathic hypoparathyroidism
0.000 0.759 0.241
E65-E68 Obesity and other hyperalimentation
0.000 0.762 0.238
E26.9 Hyperaldosteronism, unspecified
0.000 0.764 0.236
E26.8 Other hyperaldosteronism
0.000 0.764 0.236
E26.1 Secondary hyperaldosteronism
0.000 0.764 0.236
C60 Malignant neoplasm of penis
0.230 0.770 0.000
E51 Thiamine deficiency
0.000 0.775 0.225
E25.9 Adrenogenital disorder, unspecified
0.000 0.777 0.223
E25.8 Other adrenogenital disorders
0.000 0.777 0.223
E58 Dietary calcium deficiency
0.000 0.778 0.222
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.779 0.221
E20.9 Hypoparathyroidism, unspecified
0.000 0.779 0.221
E56 Other vitamin deficiencies
0.000 0.780 0.220
E22 Hyperfunction of pituitary gland
0.000 0.783 0.217
L41 Parapsoriasis
0.214 0.785 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.787 0.213
E63 Other nutritional deficiencies
0.000 0.787 0.213
E50 Vitamin A deficiency
0.000 0.787 0.213
E60 Dietary zinc deficiency
0.000 0.787 0.213
E59 Dietary selenium deficiency
0.000 0.787 0.213
E52 Niacin deficiency [pellagra]
0.000 0.787 0.213
M35 Other systemic involvement of connective tissue
0.000 0.790 0.210
E26.0 Primary hyperaldosteronism
0.000 0.791 0.209
E29.8 Other testicular dysfunction
0.000 0.794 0.206
E29.0 Testicular hyperfunction
0.000 0.794 0.206
C63 Malignant neoplasm of other and unspecified male genital organs
0.205 0.795 0.000
E29.9 Testicular dysfunction, unspecified
0.000 0.798 0.202
E61 Deficiency of other nutrient elements
0.000 0.799 0.201
E34.8 Other specified endocrine disorders
0.000 0.799 0.201
L45 Papulosquamous disorders in diseases classified elsewhere
0.193 0.807 0.000
L44 Other papulosquamous disorders
0.192 0.808 0.000
E54 Ascorbic acid deficiency
0.000 0.810 0.190
E27 Other disorders of adrenal gland
0.000 0.810 0.190
E34.3 Short stature, not elsewhere classified
0.000 0.813 0.186
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.814 0.186
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.814 0.186
E16.4 Abnormal secretion of gastrin
0.000 0.814 0.186
E16.3 Increased secretion of glucagon
0.000 0.814 0.186
M35.7 Hypermobility syndrome
0.000 0.819 0.181
C60.9 Penis, unspecified
0.179 0.821 0.000
L42 Pityriasis rosea
0.179 0.821 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.823 0.177
E34.5 Androgen resistance syndrome
0.000 0.823 0.177
E34.4 Constitutional tall stature
0.000 0.823 0.177
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.823 0.177
E34.1 Other hypersecretion of intestinal hormones
0.000 0.823 0.177
C60.1 Glans penis
0.176 0.824 0.000
E13.9 Without complications
0.000 0.824 0.176
L41.1 Pityriasis lichenoides chronica
0.176 0.824 0.000
E51.2 Wernicke's encephalopathy
0.000 0.826 0.174
E67 Other hyperalimentation
0.000 0.829 0.171
E68 Sequelae of hyperalimentation
0.000 0.829 0.171
E16.1 Other hypoglycaemia
0.000 0.830 0.170
M35.1 Other overlap syndromes
0.000 0.832 0.168
C60.8 Overlapping lesion of penis
0.165 0.835 0.000
C60.2 Body of penis
0.165 0.835 0.000
E56.1 Deficiency of vitamin K
0.000 0.835 0.165
C62 Malignant neoplasm of testis
0.163 0.837 0.000
E51.9 Thiamine deficiency, unspecified
0.000 0.838 0.162
E51.8 Other manifestations of thiamine deficiency
0.000 0.838 0.162
E51.1 Beriberi
0.000 0.838 0.162
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.840 0.159
M35.2 Behcet's disease
0.000 0.841 0.159
E56.9 Vitamin deficiency, unspecified
0.000 0.842 0.158
E56.8 Deficiency of other vitamins
0.000 0.842 0.158
E56.0 Deficiency of vitamin E
0.000 0.842 0.158
E61.2 Magnesium deficiency
0.000 0.842 0.158
C60.0 Prepuce
0.157 0.843 0.000
M35.8 Other specified systemic involvement of connective tissue
0.000 0.844 0.156
E22.8 Other hyperfunction of pituitary gland
0.000 0.844 0.155
L41.9 Parapsoriasis, unspecified
0.154 0.846 0.000
L41.8 Other parapsoriasis
0.154 0.846 0.000
L41.5 Retiform parapsoriasis
0.154 0.846 0.000
L41.4 Large plaque parapsoriasis
0.154 0.846 0.000
L41.3 Small plaque parapsoriasis
0.154 0.846 0.000
L41.2 Lymphomatoid papulosis
0.154 0.846 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.154 0.846 0.000
E50.9 Vitamin A deficiency, unspecified
0.000 0.847 0.153
E50.8 Other manifestations of vitamin A deficiency
0.000 0.847 0.153
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.847 0.153
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.847 0.153
E50.5 Vitamin A deficiency with night blindness
0.000 0.847 0.153
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.847 0.153
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.847 0.153
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.847 0.153
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.847 0.153
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.847 0.153
E63.9 Nutritional deficiency, unspecified
0.000 0.847 0.153
E63.8 Other specified nutritional deficiencies
0.000 0.847 0.153
E63.1 Imbalance of constituents of food intake
0.000 0.847 0.153
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.847 0.153
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.847 0.153
E64.8 Sequelae of other nutritional deficiencies
0.000 0.847 0.153
E64.3 Sequelae of rickets
0.000 0.847 0.153
E64.2 Sequelae of vitamin C deficiency
0.000 0.847 0.153
E64.1 Sequelae of vitamin A deficiency
0.000 0.847 0.153
E64.0 Sequelae of protein-energy malnutrition
0.000 0.847 0.153
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.849 0.151
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.849 0.151
M35.5 Multifocal fibrosclerosis
0.000 0.849 0.151
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.849 0.151
E21.0 Primary hyperparathyroidism
0.000 0.851 0.149
E53 Deficiency of other B group vitamins
0.000 0.852 0.148
C63.9 Male genital organ, unspecified
0.147 0.853 0.000
C63.8 Overlapping lesion of male genital organs
0.147 0.853 0.000
C63.7 Other specified male genital organs
0.147 0.853 0.000
C63.1 Spermatic cord
0.147 0.853 0.000
C63.0 Epididymis
0.147 0.853 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.854 0.146
E61.9 Deficiency of nutrient element, unspecified
0.000 0.855 0.145
E61.8 Deficiency of other specified nutrient elements
0.000 0.855 0.145
E61.7 Deficiency of multiple nutrient elements
0.000 0.855 0.145
E61.6 Vanadium deficiency
0.000 0.855 0.145
E61.5 Molybdenum deficiency
0.000 0.855 0.145
E61.4 Chromium deficiency
0.000 0.855 0.145
E61.3 Manganese deficiency
0.000 0.855 0.145
E61.0 Copper deficiency
0.000 0.855 0.145
E55 Vitamin D deficiency
0.000 0.856 0.144
E29.1 Testicular hypofunction
0.000 0.856 0.144
E65 Localised adiposity
0.000 0.856 0.144
E23.0 Hypopituitarism
0.000 0.856 0.144
E27.1 Primary adrenocortical insufficiency
0.000 0.857 0.143
C63.2 Scrotum
0.140 0.860 0.000
L44.9 Papulosquamous disorder, unspecified
0.138 0.862 0.000
L44.8 Other specified papulosquamous disorders
0.138 0.862 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.138 0.862 0.000
L44.3 Lichen ruber moniliformis
0.138 0.862 0.000
L44.2 Lichen striatus
0.138 0.862 0.000
L44.1 Lichen nitidus
0.138 0.862 0.000
L44.0 Pityriasis rubra pilaris
0.137 0.863 0.000
E27.5 Adrenomedullary hyperfunction
0.000 0.864 0.136
E27.0 Other adrenocortical overactivity
0.000 0.864 0.136
E27.9 Disorder of adrenal gland, unspecified
0.000 0.865 0.135
E22.1 Hyperprolactinaemia
0.000 0.867 0.133
H00.1 Chalazion
0.131 0.869 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.870 0.130
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.872 0.128
E67.8 Other specified hyperalimentation
0.000 0.877 0.122
E67.3 Hypervitaminosis D
0.000 0.877 0.122
E67.2 Megavitamin-B6 syndrome
0.000 0.877 0.122
E67.1 Hypercarotenaemia
0.000 0.877 0.122
E67.0 Hypervitaminosis A
0.000 0.877 0.122
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.878 0.122
C83.3 Large cell (diffuse)
0.000 0.878 0.122
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.880 0.120
C62.0 Undescended testis
0.117 0.883 0.000
C85.1 B-cell lymphoma, unspecified
0.000 0.884 0.116
C62.1 Descended testis
0.113 0.886 0.000
E61.1 Iron deficiency
0.000 0.888 0.112
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.888 0.112
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.890 0.110
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.891 0.108
C81 Hodgkin's disease
0.000 0.892 0.108
E53.1 Pyridoxine deficiency
0.000 0.894 0.106
E53.0 Riboflavin deficiency
0.000 0.894 0.106
E55.0 Rickets, active
0.000 0.896 0.104
E27.2 Addisonian crisis
0.000 0.897 0.103
E53.9 Vitamin B deficiency, unspecified
0.000 0.897 0.103
C81.9 Hodgkin's disease, unspecified
0.000 0.897 0.103
E34.9 Endocrine disorder, unspecified
0.001 0.901 0.099
E34.0 Carcinoid syndrome
0.001 0.905 0.094
L43 Lichen planus
0.091 0.908 0.001
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.000 0.909 0.091
C81.2 Mixed cellularity
0.000 0.909 0.091
C83.7 Burkitt's tumour
0.000 0.909 0.091
C85.0 Lymphosarcoma
0.000 0.914 0.086
C81.0 Lymphocytic predominance
0.000 0.915 0.085
E14.9 Without complications
0.000 0.915 0.085
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.916 0.084
C81.1 Nodular sclerosis
0.000 0.917 0.083
C83.1 Small cleaved cell (diffuse)
0.000 0.917 0.083
E22.0 Acromegaly and pituitary gigantism
0.001 0.919 0.080
C83.6 Undifferentiated (diffuse)
0.000 0.920 0.080
C83.4 Immunoblastic (diffuse)
0.000 0.920 0.080
C83.2 Mixed small and large cell (diffuse)
0.000 0.920 0.080
C86 Other specified types of T/NK-cell lymphoma
0.000 0.921 0.079
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.921 0.079
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.000 0.922 0.077
C81.3 Lymphocytic depletion
0.000 0.922 0.077
C88 Malignant immunoproliferative diseases
0.000 0.923 0.077
C93 Monocytic leukaemia
0.000 0.924 0.076
C83.5 Lymphoblastic (diffuse)
0.000 0.924 0.076
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.924 0.075
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.925 0.075
C94 Other leukaemias of specified cell type
0.000 0.927 0.073
C62.9 Testis, unspecified
0.073 0.927 0.000
C81.7 Other Hodgkin's disease
0.000 0.928 0.072
C85.7 Other specified types of non-Hodgkin's lymphoma
0.000 0.929 0.071
C95 Leukaemia of unspecified cell type
0.000 0.929 0.071
E27.8 Other specified disorders of adrenal gland
0.001 0.931 0.069
H00 Hordeolum and chalazion
0.068 0.931 0.000
C92 Myeloid leukaemia
0.000 0.932 0.068
L43.3 Subacute (active) lichen planus
0.065 0.934 0.001
L43.2 Lichenoid drug reaction
0.065 0.934 0.001
L43.1 Bullous lichen planus
0.065 0.934 0.001
L43.0 Hypertrophic lichen planus
0.065 0.934 0.001
C92.1 Chronic myeloid leukaemia
0.000 0.934 0.066
E04 Other non-toxic goitre
0.000 0.936 0.064
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.000 0.937 0.062
K50.0 Crohn's disease of small intestine
0.062 0.938 0.000
C82.3 Follicular lymphoma grade IIIa
0.000 0.938 0.061
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.939 0.061
C84.0 Mycosis fungoides
0.000 0.940 0.060
E16.2 Hypoglycaemia, unspecified
0.000 0.942 0.058
C84.5 Other and unspecified T-cell lymphomas
0.000 0.942 0.058
C86.5 Angioimmunoblastic T-cell lymphoma
0.000 0.943 0.057
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.000 0.943 0.057
C86.4 Blastic NK-cell lymphoma
0.000 0.943 0.057
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.000 0.943 0.057
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.000 0.943 0.057
C86.1 Hepatosplenic T-cell lymphoma
0.000 0.943 0.057
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.000 0.943 0.057
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.000 0.943 0.057
C96.8 Histiocytic sarcoma
0.000 0.943 0.057
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.943 0.057
C96.6 Unifocal Langerhans-cell histiocytosis
0.000 0.943 0.057
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.000 0.943 0.057
C96.4 Sarcoma of dendritic cells (accessory cells)
0.000 0.943 0.057
C96.3 True histiocytic lymphoma
0.000 0.943 0.057
C96.2 Malignant mast cell tumour
0.000 0.943 0.057
C96.1 Malignant histiocytosis
0.000 0.943 0.057
C96.0 Letterer-Siwe disease
0.000 0.943 0.057
C82.2 Large cell, follicular
0.000 0.943 0.056
H00.0 Hordeolum and other deep inflammation of eyelid
0.056 0.944 0.000
C88.9 Malignant immunoproliferative disease, unspecified
0.000 0.945 0.055
C88.7 Other malignant immunoproliferative diseases
0.000 0.945 0.055
C88.3 Immunoproliferative small intestinal disease
0.000 0.945 0.055
C88.2 Gamma heavy chain disease
0.000 0.945 0.055
C88.1 Alpha heavy chain disease
0.000 0.945 0.055
K60.2 Anal fissure, unspecified
0.000 0.945 0.055
C93.9 Monocytic leukaemia, unspecified
0.000 0.945 0.054
C93.7 Other monocytic leukaemia
0.000 0.945 0.054
C93.3 Juvenile myelomonocytic leukaemia
0.000 0.945 0.054
C93.2 Subacute monocytic leukaemia
0.000 0.945 0.054
C93.0 Acute monocytic leukaemia
0.000 0.945 0.054
C84.9 Mature T/NK-cell lymphoma, unspecified
0.000 0.946 0.054
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.000 0.946 0.054
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.000 0.946 0.054
C84.3 Lymphoepithelioid lymphoma
0.000 0.946 0.054
C84.2 T-zone lymphoma
0.000 0.946 0.054
C84.1 Sezary's diease
0.000 0.946 0.054
C82.6 Cutaneous follicle centre lymphoma
0.000 0.946 0.054
C82.5 Diffuse follicle centre lymphoma
0.000 0.946 0.054
K50 Crohn's disease [regional enteritis]
0.054 0.946 0.000
K50.8 Other Crohn's disease
0.054 0.946 0.000
C95.9 Leukaemia, unspecified
0.000 0.947 0.053
C94.7 Other specified leukaemias
0.000 0.947 0.053
C94.5 Acute myelofibrosis
0.000 0.947 0.053
C94.4 Acute panmyelosis
0.000 0.947 0.053
C94.3 Mast cell leukaemia
0.000 0.947 0.053
C94.2 Acute megakaryoblastic leukaemia
0.000 0.947 0.053
C94.1 Chronic erythraemia
0.000 0.947 0.053
C94.0 Acute erythraemia and erythroleukaemia
0.000 0.947 0.053
L43.8 Other lichen planus
0.052 0.947 0.001
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.000 0.948 0.052
C93.1 Chronic monocytic leukaemia
0.000 0.948 0.052
C95.7 Other leukaemia of unspecified cell type
0.000 0.949 0.051
C95.2 Subacute leukaemia of unspecified cell type
0.000 0.949 0.051
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.000 0.949 0.051
C84.8 Cutaneous T-cell lymphoma, unspecified
0.000 0.950 0.050
K60 Fissure and fistula of anal and rectal regions
0.000 0.950 0.050
C95.1 Chronic leukaemia of unspecified cell type
0.000 0.950 0.050
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.000 0.951 0.049
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.000 0.951 0.049
C92.3 Myeloid sarcoma
0.000 0.951 0.049
C92.2 Subacute myeloid leukaemia
0.000 0.951 0.049
E53.8 Deficiency of other specified B group vitamins
0.000 0.951 0.049
K90-K93 Other diseases of the digestive system
0.000 0.951 0.049
C92.5 Acute myelomonocytic leukaemia
0.000 0.952 0.048
C82.4 Follicular lymphoma grade IIIb
0.000 0.952 0.048
C82.0 Small cleaved cell, follicular
0.000 0.952 0.047
K60.3 Anal fistula
0.000 0.952 0.048
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.000 0.953 0.047
K50.1 Crohn's disease of large intestine
0.047 0.953 0.000
K60.0 Acute anal fissure
0.000 0.953 0.047
E04.8 Other specified non-toxic goitre
0.000 0.954 0.046
C91 Lymphoid leukaemia
0.000 0.954 0.046
E83 Disorders of mineral metabolism
0.038 0.956 0.005
C95.0 Acute leukaemia of unspecified cell type
0.000 0.957 0.043
C92.9 Myeloid leukaemia, unspecified
0.000 0.957 0.043
C84.4 Peripheral T-cell lymphoma
0.000 0.957 0.043
C82.1 Mixed small cleaved and large cell, follicular
0.000 0.958 0.042
C88.0 Waldenstrom's macroglobulinaemia
0.000 0.958 0.042
K60.5 Anorectal fistula
0.000 0.959 0.041
C91.9 Lymphoid leukaemia, unspecified
0.000 0.960 0.040
E04.0 Non-toxic diffuse goitre
0.000 0.960 0.039
C83.0 Small cell (diffuse)
0.000 0.961 0.038
C92.4 Acute promyelocytic leukaemia
0.000 0.962 0.038
K60.4 Rectal fistula
0.000 0.962 0.038
M35.3 Polymyalgia rheumatica
0.000 0.964 0.036
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.965 0.035
Z51.3 Blood transfusion without reported diagnosis
0.000 0.965 0.035
E55.9 Vitamin D deficiency, unspecified
0.000 0.965 0.035
G63.2 Diabetic polyneuropathy
0.035 0.965 0.000
C92.7 Other myeloid leukaemia
0.001 0.967 0.033
C91.8 Mature B-cell leukaemia Burkitt-type
0.000 0.967 0.033
C91.7 Other lymphoid leukaemia
0.000 0.967 0.033
C91.6 Prolymphocytic leukaemia of T-cell type
0.000 0.967 0.033
C91.3 Prolymphocytic leukaemia
0.000 0.967 0.033
C91.2 Subacute lymphocytic leukaemia
0.000 0.967 0.033
C91.5 Adult T-cell leukaemia
0.000 0.967 0.033
E83.9 Disorder of mineral metabolism, unspecified
0.029 0.968 0.004
E83.8 Other disorders of mineral metabolism
0.028 0.968 0.004
E83.2 Disorders of zinc metabolism
0.028 0.968 0.004
E83.0 Disorders of copper metabolism
0.028 0.968 0.004
C90 Multiple myeloma and malignant plasma cell neoplasms
0.001 0.970 0.029
N05.2 Diffuse membranous glomerulonephritis
0.000 0.971 0.029
N05 Unspecified nephritic syndrome
0.000 0.972 0.028
N05.9 Unspecified
0.000 0.972 0.028
C91.4 Hairy-cell leukaemia
0.000 0.974 0.025
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.975 0.025
K93.1 Megacolon in Chagas' disease
0.000 0.975 0.025
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.975 0.025
Z85.4 Personal history of malignant neoplasm of genital organs
0.025 0.975 0.000
C91.0 Acute lymphoblastic leukaemia
0.000 0.976 0.024
N05.1 Focal and segmental glomerular lesions
0.000 0.976 0.024
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.977 0.023
C90.1 Plasma cell leukaemia
0.001 0.977 0.022
C92.0 Acute myeloid leukaemia
0.000 0.977 0.022
K50.9 Crohn's disease, unspecified
0.022 0.978 0.000
N05.6 Dense deposit disease
0.000 0.980 0.020
N05.4 Diffuse endocapillary proliferative glomerulonephritis
0.000 0.980 0.020
N05.0 Minor glomerular abnormality
0.000 0.980 0.020

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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