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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1265064
log Bayes Factor = 138.406
Chromosome 6   position 31,077,732  (GRCh37) Explore rs1265064 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E07 Other disorders of thyroid
0.000 0.001 0.999
E07.9 Disorder of thyroid, unspecified
0.000 0.001 0.999
L40 Psoriasis
0.999 0.001 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.005 0.995
L40.0 Psoriasis vulgaris
0.987 0.013 0.000
L40.5 Arthropathic psoriasis
0.982 0.018 0.000
E83.1 Disorders of iron metabolism
0.979 0.021 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.141 0.859
K90 Intestinal malabsorption
0.000 0.142 0.858
L40.4 Guttate psoriasis
0.836 0.164 0.000
E03.8 Other specified hypothyroidism
0.000 0.176 0.824
L40.3 Pustulosis palmaris et plantaris
0.810 0.190 0.000
E06 Thyroiditis
0.000 0.213 0.787
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.235 0.765
K90.9 Intestinal malabsorption, unspecified
0.000 0.238 0.762
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.239 0.761
E07.8 Other specified disorders of thyroid
0.000 0.251 0.749
E10.9 Without complications
0.000 0.253 0.747
E10 Insulin-dependent diabetes mellitus
0.000 0.263 0.737
L40.1 Generalised pustular psoriasis
0.730 0.270 0.000
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E10.3 With ophthalmic complications
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E07.1 Dyshormogenetic goitre
0.000 0.283 0.716
E07.0 Hypersecretion of calcitonin
0.000 0.283 0.716
L40.2 Acrodermatitis continua
0.716 0.284 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.284 0.716
C83.3 Large cell (diffuse)
0.000 0.286 0.714
E10-E14 Diabetes mellitus
0.000 0.292 0.708
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.295 0.705
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.301 0.699
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.303 0.697
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.307 0.693
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.310 0.690
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.312 0.688
C81 Hodgkin's disease
0.000 0.320 0.680
E06.3 Autoimmune thyroiditis
0.000 0.321 0.679
E05.8 Other thyrotoxicosis
0.000 0.327 0.673
C85.1 B-cell lymphoma, unspecified
0.000 0.332 0.668
C61 Malignant neoplasm of prostate
0.668 0.332 0.000
L40.8 Other psoriasis
0.662 0.338 0.000
K90.8 Other intestinal malabsorption
0.000 0.347 0.653
C81.9 Hodgkin's disease, unspecified
0.000 0.349 0.651
E10.2 With renal complications
0.000 0.355 0.645
E06.5 Other chronic thyroiditis
0.000 0.366 0.634
M35.0 Sicca syndrome [Sjogren]
0.000 0.376 0.624
K90.3 Pancreatic steatorrhoea
0.000 0.385 0.615
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.385 0.615
K90.1 Tropical sprue
0.000 0.385 0.615
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.389 0.611
E03.1 Congenital hypothyroidism without goitre
0.000 0.392 0.608
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.000 0.398 0.602
C81.2 Mixed cellularity
0.000 0.425 0.575
E06.4 Drug-induced thyroiditis
0.000 0.436 0.564
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.436 0.564
E06.0 Acute thyroiditis
0.000 0.436 0.564
C81.1 Nodular sclerosis
0.000 0.436 0.564
C83.7 Burkitt's tumour
0.000 0.448 0.552
E06.1 Subacute thyroiditis
0.000 0.448 0.552
E14 Unspecified diabetes mellitus
0.000 0.451 0.549
E10.4 With neurological complications
0.000 0.456 0.544
C81.0 Lymphocytic predominance
0.000 0.460 0.540
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.463 0.537
E10.7 With multiple complications
0.000 0.465 0.535
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
C83.1 Small cleaved cell (diffuse)
0.000 0.491 0.509
E12 Malnutrition-related diabetes mellitus
0.000 0.492 0.508
E14.3 With ophthalmic complications
0.000 0.494 0.506
E10.0 With coma
0.000 0.495 0.505
C83.6 Undifferentiated (diffuse)
0.000 0.500 0.500
C83.4 Immunoblastic (diffuse)
0.000 0.500 0.500
C83.2 Mixed small and large cell (diffuse)
0.000 0.500 0.500
C86 Other specified types of T/NK-cell lymphoma
0.000 0.501 0.499
C85.0 Lymphosarcoma
0.000 0.503 0.497
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.505 0.495
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.000 0.512 0.487
C81.3 Lymphocytic depletion
0.000 0.512 0.487
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.515 0.485
C88 Malignant immunoproliferative diseases
0.000 0.515 0.485
E40-E46 Malnutrition
0.000 0.519 0.481
C93 Monocytic leukaemia
0.000 0.520 0.480
C83.5 Lymphoblastic (diffuse)
0.000 0.527 0.473
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.537 0.463
C94 Other leukaemias of specified cell type
0.000 0.538 0.461
E10.8 With unspecified complications
0.000 0.540 0.460
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.540 0.460
C95 Leukaemia of unspecified cell type
0.000 0.542 0.458
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.543 0.457
C81.7 Other Hodgkin's disease
0.000 0.543 0.456
C82.3 Follicular lymphoma grade IIIa
0.000 0.548 0.451
E10.6 With other specified complications
0.000 0.554 0.446
E20-E35 Disorders of other endocrine glands
0.000 0.564 0.436
E13 Other specified diabetes mellitus
0.000 0.566 0.433
E14.5 With peripheral circulatory complications
0.000 0.574 0.426
E28 Ovarian dysfunction
0.000 0.581 0.419
C82.2 Large cell, follicular
0.000 0.593 0.407
E14.1 With ketoacidosis
0.000 0.593 0.407
E10.5 With peripheral circulatory complications
0.000 0.599 0.401
E28.3 Primary ovarian failure
0.000 0.602 0.398
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.000 0.604 0.396
E14.7 With multiple complications
0.000 0.606 0.394
E14.0 With coma
0.000 0.606 0.394
E14.8 With unspecified complications
0.000 0.609 0.391
C82.6 Cutaneous follicle centre lymphoma
0.000 0.615 0.385
C82.5 Diffuse follicle centre lymphoma
0.000 0.615 0.385
E14.2 Withrenal complications
0.000 0.619 0.381
E14.6 With other specified complications
0.000 0.624 0.376
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.000 0.626 0.374
E14.4 With neurological complications
0.000 0.631 0.369
E24 Cushing's syndrome
0.000 0.633 0.367
E12.9 Without complications
0.000 0.636 0.364
E12.8 With unspecified complications
0.000 0.636 0.364
E12.7 With multiple complications
0.000 0.636 0.364
E12.6 With other specified complications
0.000 0.636 0.364
E12.5 With peripheral circulatory complications
0.000 0.636 0.364
E12.4 With neurological complications
0.000 0.636 0.364
E12.3 With ophthalmic complications
0.000 0.636 0.364
E12.2 With renal complications
0.000 0.636 0.364
E12.1 With ketoacidosis
0.000 0.636 0.364
E12.0 With coma
0.000 0.636 0.364
C85.7 Other specified types of non-Hodgkin's lymphoma
0.000 0.636 0.364
C84.0 Mycosis fungoides
0.000 0.637 0.363
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.000 0.638 0.361
C86.5 Angioimmunoblastic T-cell lymphoma
0.000 0.638 0.361
E23 Hypofunction and other disorders of pituitary gland
0.000 0.639 0.361
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.000 0.642 0.357
C86.4 Blastic NK-cell lymphoma
0.000 0.642 0.357
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.000 0.642 0.357
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.000 0.642 0.357
C86.1 Hepatosplenic T-cell lymphoma
0.000 0.642 0.357
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.000 0.642 0.357
C95.9 Leukaemia, unspecified
0.000 0.644 0.355
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.000 0.645 0.355
C96.8 Histiocytic sarcoma
0.000 0.645 0.355
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.645 0.355
C96.6 Unifocal Langerhans-cell histiocytosis
0.000 0.645 0.355
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.000 0.645 0.355
C96.4 Sarcoma of dendritic cells (accessory cells)
0.000 0.645 0.355
C96.3 True histiocytic lymphoma
0.000 0.645 0.355
C96.2 Malignant mast cell tumour
0.000 0.645 0.355
C96.1 Malignant histiocytosis
0.000 0.645 0.355
C96.0 Letterer-Siwe disease
0.000 0.645 0.355
E06.9 Thyroiditis, unspecified
0.000 0.646 0.353
C88.9 Malignant immunoproliferative disease, unspecified
0.000 0.652 0.348
C88.7 Other malignant immunoproliferative diseases
0.000 0.652 0.348
C88.3 Immunoproliferative small intestinal disease
0.000 0.652 0.348
C88.2 Gamma heavy chain disease
0.000 0.652 0.348
C88.1 Alpha heavy chain disease
0.000 0.652 0.348
E28.2 Polycystic ovarian syndrome
0.000 0.654 0.346
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.655 0.345
E45 Retarded development following protein-energy malnutrition
0.000 0.655 0.345
E43 Unspecified severe protein-energy malnutrition
0.000 0.655 0.345
E42 Marasmic kwashiorkor
0.000 0.655 0.345
E41 Nutritional marasmus
0.000 0.655 0.345
E40 Kwashiorkor
0.000 0.655 0.345
C93.9 Monocytic leukaemia, unspecified
0.000 0.656 0.344
C93.7 Other monocytic leukaemia
0.000 0.656 0.344
C93.3 Juvenile myelomonocytic leukaemia
0.000 0.656 0.344
C93.2 Subacute monocytic leukaemia
0.000 0.656 0.344
C93.0 Acute monocytic leukaemia
0.000 0.656 0.344
C82.4 Follicular lymphoma grade IIIb
0.000 0.657 0.343
C84.5 Other and unspecified T-cell lymphomas
0.000 0.658 0.341
E13.3 With ophthalmic complications
0.000 0.660 0.339
E10.1 With ketoacidosis
0.000 0.666 0.334
C92 Myeloid leukaemia
0.000 0.666 0.334
E23.2 Diabetes insipidus
0.000 0.666 0.334
E15 Nondiabetic hypoglycaemic coma
0.000 0.668 0.332
C94.7 Other specified leukaemias
0.000 0.669 0.331
C94.5 Acute myelofibrosis
0.000 0.669 0.331
C94.4 Acute panmyelosis
0.000 0.669 0.331
C94.3 Mast cell leukaemia
0.000 0.669 0.331
C94.2 Acute megakaryoblastic leukaemia
0.000 0.669 0.331
C94.1 Chronic erythraemia
0.000 0.669 0.331
C94.0 Acute erythraemia and erythroleukaemia
0.000 0.669 0.331
C93.1 Chronic monocytic leukaemia
0.000 0.671 0.329
C95.7 Other leukaemia of unspecified cell type
0.000 0.671 0.328
C95.2 Subacute leukaemia of unspecified cell type
0.000 0.671 0.328
C82.0 Small cleaved cell, follicular
0.000 0.672 0.328
E24.2 Drug-induced Cushing's syndrome
0.000 0.672 0.328
C84.9 Mature T/NK-cell lymphoma, unspecified
0.000 0.672 0.328
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.000 0.672 0.328
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.000 0.672 0.328
C84.3 Lymphoepithelioid lymphoma
0.000 0.672 0.328
C84.2 T-zone lymphoma
0.000 0.672 0.328
C84.1 Sezary's diease
0.000 0.672 0.328
E46 Unspecified protein-energy malnutrition
0.000 0.680 0.320
E31 Polyglandular dysfunction
0.000 0.683 0.317
E50-E64 Other nutritional deficiencies
0.000 0.684 0.316
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.687 0.313
E32 Diseases of thymus
0.000 0.687 0.313
E30 Disorders of puberty, not elsewhere classified
0.000 0.687 0.313
E13.8 With unspecified complications
0.000 0.689 0.311
E13.7 With multiple complications
0.000 0.689 0.311
E13.6 With other specified complications
0.000 0.689 0.311
E13.5 With peripheral circulatory complications
0.000 0.689 0.311
E13.4 With neurological complications
0.000 0.689 0.311
E13.2 With renal complications
0.000 0.689 0.311
E13.1 With ketoacidosis
0.000 0.689 0.311
E13.0 With coma
0.000 0.689 0.311
C91 Lymphoid leukaemia
0.000 0.694 0.306
C95.1 Chronic leukaemia of unspecified cell type
0.000 0.694 0.306
C84.8 Cutaneous T-cell lymphoma, unspecified
0.000 0.695 0.305
C82.1 Mixed small cleaved and large cell, follicular
0.000 0.695 0.304
C92.1 Chronic myeloid leukaemia
0.000 0.697 0.303
E28.9 Ovarian dysfunction, unspecified
0.000 0.700 0.300
E28.8 Other ovarian dysfunction
0.000 0.700 0.300
E28.1 Androgen excess
0.000 0.700 0.300
E28.0 Oestrogen excess
0.000 0.700 0.300
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.000 0.702 0.298
E16 Other disorders of pancreatic internal secretion
0.000 0.710 0.290
E26 Hyperaldosteronism
0.000 0.715 0.285
E20 Hypoparathyroidism
0.000 0.717 0.283
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.718 0.282
C95.0 Acute leukaemia of unspecified cell type
0.000 0.721 0.278
E23.7 Disorder of pituitary gland, unspecified
0.000 0.724 0.276
L40-L45 Papulosquamous disorders
0.275 0.725 0.000
E24.0 Pituitary-dependent Cushing's disease
0.000 0.728 0.272
E23.6 Other disorders of pituitary gland
0.000 0.733 0.267
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.737 0.263
E24.3 Ectopic ACTH syndrome
0.000 0.737 0.263
E24.1 Nelson's syndrome
0.000 0.737 0.263
C91.9 Lymphoid leukaemia, unspecified
0.000 0.739 0.261
E25 Adrenogenital disorders
0.000 0.740 0.260
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.741 0.259
E23.1 Drug-induced hypopituitarism
0.000 0.741 0.259
C88.0 Waldenstrom's macroglobulinaemia
0.000 0.742 0.258
M35 Other systemic involvement of connective tissue
0.000 0.743 0.257
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.745 0.255
E24.8 Other Cushing's syndrome
0.000 0.752 0.248
E44.1 Mild protein-energy malnutrition
0.000 0.753 0.247
E44.0 Moderate protein-energy malnutrition
0.000 0.753 0.247
C83.0 Small cell (diffuse)
0.000 0.756 0.243
E24.9 Cushing's syndrome, unspecified
0.000 0.758 0.241
E51 Thiamine deficiency
0.000 0.759 0.240
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.000 0.761 0.239
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.000 0.761 0.239
C92.3 Myeloid sarcoma
0.000 0.761 0.239
C92.2 Subacute myeloid leukaemia
0.000 0.761 0.239
C84.4 Peripheral T-cell lymphoma
0.000 0.761 0.238
E58 Dietary calcium deficiency
0.000 0.763 0.237
E21.3 Hyperparathyroidism, unspecified
0.000 0.765 0.235
C92.5 Acute myelomonocytic leukaemia
0.000 0.765 0.235
E29 Testicular dysfunction
0.000 0.765 0.235
E56 Other vitamin deficiencies
0.000 0.765 0.235
E65-E68 Obesity and other hyperalimentation
0.000 0.767 0.233
E31.0 Autoimmune polyglandular failure
0.000 0.769 0.231
E31.9 Polyglandular dysfunction, unspecified
0.000 0.773 0.227
E31.8 Other polyglandular dysfunction
0.000 0.773 0.227
E31.1 Polyglandular hyperfunction
0.000 0.773 0.227
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.773 0.226
E63 Other nutritional deficiencies
0.000 0.773 0.226
E50 Vitamin A deficiency
0.000 0.773 0.226
E60 Dietary zinc deficiency
0.000 0.773 0.226
E59 Dietary selenium deficiency
0.000 0.773 0.226
E52 Niacin deficiency [pellagra]
0.000 0.773 0.226
L41 Parapsoriasis
0.225 0.775 0.000
E30.9 Disorder of puberty, unspecified
0.000 0.775 0.224
E30.8 Other disorders of puberty
0.000 0.775 0.224
E30.1 Precocious puberty
0.000 0.775 0.224
E30.0 Delayed puberty
0.000 0.775 0.224
E32.9 Disease of thymus, unspecified
0.000 0.775 0.224
E32.8 Other diseases of thymus
0.000 0.775 0.224
E32.1 Abscess of thymus
0.000 0.775 0.224
E32.0 Persistent hyperplasia of thymus
0.000 0.775 0.224
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.775 0.224
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.775 0.224
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.775 0.224
C91.5 Adult T-cell leukaemia
0.000 0.779 0.221
C91.8 Mature B-cell leukaemia Burkitt-type
0.000 0.780 0.220
C91.7 Other lymphoid leukaemia
0.000 0.780 0.220
C91.6 Prolymphocytic leukaemia of T-cell type
0.000 0.780 0.220
C91.3 Prolymphocytic leukaemia
0.000 0.780 0.220
C91.2 Subacute lymphocytic leukaemia
0.000 0.780 0.220
C60-C63 Malignant neoplasms of male genital organs
0.219 0.781 0.000
E34 Other endocrine disorders
0.001 0.781 0.218
M35.7 Hypermobility syndrome
0.000 0.781 0.219
E61 Deficiency of other nutrient elements
0.000 0.784 0.216
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.786 0.214
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.789 0.211
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.792 0.208
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.792 0.208
E16.4 Abnormal secretion of gastrin
0.000 0.792 0.208
E16.3 Increased secretion of glucagon
0.000 0.792 0.208
E22 Hyperfunction of pituitary gland
0.000 0.794 0.206
E21.2 Other hyperparathyroidism
0.000 0.795 0.205
E26.9 Hyperaldosteronism, unspecified
0.000 0.795 0.205
E26.8 Other hyperaldosteronism
0.000 0.795 0.205
E26.1 Secondary hyperaldosteronism
0.000 0.795 0.205
E20.8 Other hypoparathyroidism
0.000 0.797 0.203
E20.1 Pseudohypoparathyroidism
0.000 0.797 0.203
E20.0 Idiopathic hypoparathyroidism
0.000 0.797 0.203
E54 Ascorbic acid deficiency
0.000 0.797 0.203
C90 Multiple myeloma and malignant plasma cell neoplasms
0.001 0.797 0.202
C92.9 Myeloid leukaemia, unspecified
0.000 0.797 0.203
H00.1 Chalazion
0.199 0.801 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.197 0.802 0.000
L44 Other papulosquamous disorders
0.196 0.803 0.000
M35.2 Behcet's disease
0.000 0.804 0.196
M35.8 Other specified systemic involvement of connective tissue
0.000 0.808 0.192
E21.4 Other specified disorders of parathyroid gland
0.000 0.810 0.190
C92.4 Acute promyelocytic leukaemia
0.000 0.811 0.189
L41.1 Pityriasis lichenoides chronica
0.189 0.811 0.000
E51.2 Wernicke's encephalopathy
0.000 0.813 0.187
E25.9 Adrenogenital disorder, unspecified
0.000 0.813 0.186
E25.8 Other adrenogenital disorders
0.000 0.813 0.186
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.815 0.185
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.815 0.185
M35.5 Multifocal fibrosclerosis
0.000 0.815 0.185
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.815 0.185
E16.1 Other hypoglycaemia
0.000 0.816 0.184
C91.4 Hairy-cell leukaemia
0.000 0.817 0.183
C92.7 Other myeloid leukaemia
0.000 0.818 0.181
M35.1 Other overlap syndromes
0.000 0.819 0.181
E34.8 Other specified endocrine disorders
0.000 0.820 0.180
L42 Pityriasis rosea
0.180 0.820 0.000
E26.0 Primary hyperaldosteronism
0.000 0.823 0.177
E13.9 Without complications
0.000 0.823 0.177
E56.1 Deficiency of vitamin K
0.000 0.823 0.177
E20.9 Hypoparathyroidism, unspecified
0.000 0.826 0.174
E51.9 Thiamine deficiency, unspecified
0.000 0.827 0.173
E51.8 Other manifestations of thiamine deficiency
0.000 0.827 0.173
E51.1 Beriberi
0.000 0.827 0.173
E61.2 Magnesium deficiency
0.000 0.829 0.171
E29.8 Other testicular dysfunction
0.000 0.831 0.169
E29.0 Testicular hyperfunction
0.000 0.831 0.169
E56.9 Vitamin deficiency, unspecified
0.000 0.831 0.168
E56.8 Deficiency of other vitamins
0.000 0.831 0.168
E56.0 Deficiency of vitamin E
0.000 0.831 0.168
E67 Other hyperalimentation
0.000 0.833 0.167
E68 Sequelae of hyperalimentation
0.000 0.833 0.167
C60 Malignant neoplasm of penis
0.166 0.834 0.000
C91.0 Acute lymphoblastic leukaemia
0.000 0.834 0.166
E29.9 Testicular dysfunction, unspecified
0.000 0.834 0.166
E34.3 Short stature, not elsewhere classified
0.000 0.834 0.166
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.837 0.163
E50.9 Vitamin A deficiency, unspecified
0.000 0.837 0.162
E50.8 Other manifestations of vitamin A deficiency
0.000 0.837 0.162
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.837 0.162
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.837 0.162
E50.5 Vitamin A deficiency with night blindness
0.000 0.837 0.162
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.837 0.162
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.837 0.162
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.837 0.162
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.837 0.162
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.837 0.162
E63.9 Nutritional deficiency, unspecified
0.000 0.837 0.162
E63.8 Other specified nutritional deficiencies
0.000 0.837 0.162
E63.1 Imbalance of constituents of food intake
0.000 0.837 0.162
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.837 0.162
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.837 0.162
E64.8 Sequelae of other nutritional deficiencies
0.000 0.837 0.162
E64.3 Sequelae of rickets
0.000 0.837 0.162
E64.2 Sequelae of vitamin C deficiency
0.000 0.837 0.162
E64.1 Sequelae of vitamin A deficiency
0.000 0.837 0.162
E64.0 Sequelae of protein-energy malnutrition
0.000 0.837 0.162
L41.9 Parapsoriasis, unspecified
0.161 0.838 0.000
L41.8 Other parapsoriasis
0.161 0.838 0.000
L41.5 Retiform parapsoriasis
0.161 0.838 0.000
L41.4 Large plaque parapsoriasis
0.161 0.838 0.000
L41.3 Small plaque parapsoriasis
0.161 0.838 0.000
L41.2 Lymphomatoid papulosis
0.161 0.838 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.161 0.838 0.000
E27 Other disorders of adrenal gland
0.000 0.839 0.161
E55 Vitamin D deficiency
0.000 0.842 0.158
C90.1 Plasma cell leukaemia
0.001 0.842 0.157
E34.5 Androgen resistance syndrome
0.001 0.843 0.157
E34.4 Constitutional tall stature
0.001 0.843 0.157
E34.2 Ectopic hormone secretion, not elsewhere classified
0.001 0.843 0.157
E34.1 Other hypersecretion of intestinal hormones
0.001 0.843 0.157
E14.9 Without complications
0.000 0.844 0.156
E61.9 Deficiency of nutrient element, unspecified
0.000 0.845 0.155
E61.8 Deficiency of other specified nutrient elements
0.000 0.845 0.155
E61.7 Deficiency of multiple nutrient elements
0.000 0.845 0.155
E61.6 Vanadium deficiency
0.000 0.845 0.155
E61.5 Molybdenum deficiency
0.000 0.845 0.155
E61.4 Chromium deficiency
0.000 0.845 0.155
E61.3 Manganese deficiency
0.000 0.845 0.155
E61.0 Copper deficiency
0.000 0.845 0.155
C63 Malignant neoplasm of other and unspecified male genital organs
0.151 0.849 0.000
E53 Deficiency of other B group vitamins
0.000 0.851 0.149
E22.8 Other hyperfunction of pituitary gland
0.000 0.852 0.148
L44.9 Papulosquamous disorder, unspecified
0.141 0.859 0.000
L44.8 Other specified papulosquamous disorders
0.141 0.859 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.141 0.859 0.000
L44.3 Lichen ruber moniliformis
0.141 0.859 0.000
L44.2 Lichen striatus
0.141 0.859 0.000
L44.1 Lichen nitidus
0.141 0.859 0.000
C90.3 Solitary plasmacytoma
0.001 0.859 0.140
L44.0 Pityriasis rubra pilaris
0.140 0.860 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.860 0.139
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.001 0.866 0.133
E65 Localised adiposity
0.000 0.867 0.133
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.867 0.132
C60.9 Penis, unspecified
0.128 0.872 0.000
C60.1 Glans penis
0.126 0.873 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.877 0.123
C62 Malignant neoplasm of testis
0.121 0.879 0.000
E61.1 Iron deficiency
0.000 0.879 0.121
E67.8 Other specified hyperalimentation
0.000 0.880 0.120
E67.3 Hypervitaminosis D
0.000 0.880 0.120
E67.2 Megavitamin-B6 syndrome
0.000 0.880 0.120
E67.1 Hypercarotenaemia
0.000 0.880 0.120
E67.0 Hypervitaminosis A
0.000 0.880 0.120
C60.8 Overlapping lesion of penis
0.119 0.880 0.000
C60.2 Body of penis
0.119 0.880 0.000
E27.9 Disorder of adrenal gland, unspecified
0.000 0.883 0.117
C92.0 Acute myeloid leukaemia
0.000 0.883 0.117
E27.5 Adrenomedullary hyperfunction
0.000 0.885 0.115
E27.0 Other adrenocortical overactivity
0.000 0.885 0.115
E55.0 Rickets, active
0.000 0.886 0.113
C60.0 Prepuce
0.113 0.887 0.000
E22.1 Hyperprolactinaemia
0.000 0.888 0.111
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.890 0.110
H00 Hordeolum and chalazion
0.109 0.891 0.000
C63.9 Male genital organ, unspecified
0.108 0.892 0.000
C63.8 Overlapping lesion of male genital organs
0.108 0.892 0.000
C63.7 Other specified male genital organs
0.108 0.892 0.000
C63.1 Spermatic cord
0.108 0.892 0.000
C63.0 Epididymis
0.108 0.892 0.000
E53.1 Pyridoxine deficiency
0.000 0.893 0.107
E53.0 Riboflavin deficiency
0.000 0.893 0.107
C63.2 Scrotum
0.102 0.898 0.000
E53.9 Vitamin B deficiency, unspecified
0.000 0.900 0.100
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.901 0.099
E23.0 Hypopituitarism
0.000 0.902 0.098
E29.1 Testicular hypofunction
0.000 0.903 0.097
L43 Lichen planus
0.093 0.907 0.000
E34.9 Endocrine disorder, unspecified
0.001 0.908 0.091
H00.0 Hordeolum and other deep inflammation of eyelid
0.091 0.909 0.000
C62.0 Undescended testis
0.087 0.913 0.000
E22.0 Acromegaly and pituitary gigantism
0.000 0.914 0.086
E27.2 Addisonian crisis
0.000 0.916 0.084
C62.1 Descended testis
0.083 0.916 0.000
M35.3 Polymyalgia rheumatica
0.000 0.917 0.083
C90.2 Plasmacytoma, extramedullary
0.002 0.919 0.080
E34.0 Carcinoid syndrome
0.001 0.924 0.075
C91.1 Chronic lymphocytic leukaemia
0.000 0.925 0.075
K60.2 Anal fissure, unspecified
0.000 0.929 0.071
E16.2 Hypoglycaemia, unspecified
0.000 0.932 0.068
L43.3 Subacute (active) lichen planus
0.067 0.933 0.000
L43.2 Lichenoid drug reaction
0.067 0.933 0.000
L43.1 Bullous lichen planus
0.067 0.933 0.000
L43.0 Hypertrophic lichen planus
0.067 0.933 0.000
E21.0 Primary hyperparathyroidism
0.000 0.934 0.066
E27.8 Other specified disorders of adrenal gland
0.000 0.935 0.065
K60 Fissure and fistula of anal and rectal regions
0.000 0.937 0.063
E04 Other non-toxic goitre
0.000 0.939 0.060
K60.0 Acute anal fissure
0.000 0.940 0.059
N05.2 Diffuse membranous glomerulonephritis
0.000 0.942 0.058
C62.9 Testis, unspecified
0.058 0.942 0.000
N05.9 Unspecified
0.000 0.943 0.057
N05 Unspecified nephritic syndrome
0.000 0.943 0.057
K60.5 Anorectal fistula
0.000 0.943 0.057
K60.3 Anal fistula
0.000 0.945 0.055
K90-K93 Other diseases of the digestive system
0.000 0.947 0.053
E83 Disorders of mineral metabolism
0.046 0.947 0.007
L43.8 Other lichen planus
0.051 0.948 0.000
K60.4 Rectal fistula
0.000 0.951 0.049
N05.1 Focal and segmental glomerular lesions
0.000 0.952 0.048
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.953 0.047
E53.8 Deficiency of other specified B group vitamins
0.000 0.954 0.046
E55.9 Vitamin D deficiency, unspecified
0.000 0.955 0.045
E04.8 Other specified non-toxic goitre
0.000 0.956 0.043
Z51.3 Blood transfusion without reported diagnosis
0.000 0.957 0.043
N05.6 Dense deposit disease
0.000 0.959 0.041
N05.4 Diffuse endocapillary proliferative glomerulonephritis
0.000 0.959 0.041
N05.0 Minor glomerular abnormality
0.000 0.959 0.041
N05.3 Diffuse mesangial proliferative glomerulonephritis
0.000 0.960 0.040
E83.9 Disorder of mineral metabolism, unspecified
0.035 0.960 0.005
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.962 0.038
E83.8 Other disorders of mineral metabolism
0.033 0.962 0.005
E83.2 Disorders of zinc metabolism
0.033 0.962 0.005
E83.0 Disorders of copper metabolism
0.033 0.962 0.005
N05.8 Other
0.000 0.962 0.038
N05.7 Diffuse crescentic glomerulonephritis
0.000 0.962 0.038
E04.0 Non-toxic diffuse goitre
0.000 0.963 0.037
S72.30 Fracture of shaft of femur (closed)
0.032 0.968 0.000
S72.3 Fracture of shaft of femur
0.030 0.970 0.000
S72 Fracture of femur
0.028 0.972 0.000
K50.0 Crohn's disease of small intestine
0.028 0.972 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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