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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1265086
log Bayes Factor = 127.923
Chromosome 6   position 31,109,882  (GRCh37) Explore rs1265086 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
M45.X9 Ankylosing spondylitis (Site unspecified)
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.001 0.999
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.005 0.995
C83.3 Large cell (diffuse)
0.000 0.005 0.995
C85.1 B-cell lymphoma, unspecified
0.000 0.006 0.994
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.006 0.994
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.007 0.993
D64.9 Anaemia, unspecified
0.000 0.012 0.988
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.013 0.987
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.015 0.985
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.030 0.970
L40.0 Psoriasis vulgaris
0.000 0.046 0.954
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.065 0.935
E10 Insulin-dependent diabetes mellitus
0.000 0.069 0.931
E10-E14 Diabetes mellitus
0.000 0.071 0.929
E10.9 Without complications
0.000 0.080 0.920
E10.3 With ophthalmic complications
0.000 0.103 0.897
M45 Ankylosing spondylitis
0.862 0.138 0.000
K75 Other inflammatory liver diseases
0.000 0.144 0.856
K75.4 Autoimmune hepatitis
0.000 0.154 0.846
E03.8 Other specified hypothyroidism
0.000 0.155 0.845
E40-E46 Malnutrition
0.000 0.158 0.842
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.000 0.158 0.842
E10.1 With ketoacidosis
0.000 0.158 0.842
K75.8 Other specified inflammatory liver diseases
0.000 0.159 0.841
C82.3 Follicular lymphoma grade IIIa
0.000 0.162 0.838
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.000 0.166 0.834
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.173 0.827
D64 Other anaemias
0.000 0.174 0.826
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.177 0.823
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.177 0.823
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.823 0.177 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.820 0.180 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.187 0.813
K70-K77 Diseases of liver
0.000 0.193 0.807
C82.2 Large cell, follicular
0.000 0.198 0.802
K75.9 Inflammatory liver disease, unspecified
0.000 0.205 0.795
L40.1 Generalised pustular psoriasis
0.000 0.218 0.782
E46 Unspecified protein-energy malnutrition
0.000 0.225 0.775
C82.0 Small cleaved cell, follicular
0.000 0.227 0.773
K73 Chronic hepatitis, not elsewhere classified
0.000 0.234 0.766
E20-E35 Disorders of other endocrine glands
0.000 0.235 0.765
K74 Fibrosis and cirrhosis of liver
0.000 0.239 0.761
E06 Thyroiditis
0.000 0.240 0.760
D60-D64 Aplastic and other anaemias
0.000 0.241 0.759
L40.8 Other psoriasis
0.000 0.241 0.759
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.244 0.756
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.244 0.756
E07 Other disorders of thyroid
0.000 0.246 0.754
E16 Other disorders of pancreatic internal secretion
0.000 0.250 0.749
E10.6 With other specified complications
0.000 0.252 0.748
L40.4 Guttate psoriasis
0.000 0.258 0.742
D62 Acute posthaemorrhagic anaemia
0.000 0.278 0.722
K74.0 Hepatic fibrosis
0.000 0.280 0.720
C88 Malignant immunoproliferative diseases
0.000 0.281 0.719
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.282 0.718
K72 Hepatic failure, not elsewhere classified
0.000 0.282 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.285 0.715
D61 Other aplastic anaemias
0.000 0.285 0.715
E14 Unspecified diabetes mellitus
0.000 0.285 0.715
E24 Cushing's syndrome
0.000 0.285 0.715
C83.7 Burkitt's tumour
0.000 0.286 0.714
C85.0 Lymphosarcoma
0.000 0.286 0.714
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.288 0.712
C83.6 Undifferentiated (diffuse)
0.000 0.288 0.712
C83.4 Immunoblastic (diffuse)
0.000 0.288 0.712
C83.2 Mixed small and large cell (diffuse)
0.000 0.288 0.712
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.288 0.712
C86 Other specified types of T/NK-cell lymphoma
0.000 0.290 0.710
C82.6 Cutaneous follicle centre lymphoma
0.000 0.292 0.708
C82.5 Diffuse follicle centre lymphoma
0.000 0.292 0.708
M45.X2 Ankylosing spondylitis (Cervical region)
0.700 0.300 0.000
C81 Hodgkin's disease
0.000 0.307 0.693
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.310 0.689
C84.5 Other and unspecified T-cell lymphomas
0.000 0.316 0.684
E10.8 With unspecified complications
0.000 0.318 0.682
E21.3 Hyperparathyroidism, unspecified
0.000 0.318 0.682
K71 Toxic liver disease
0.000 0.322 0.678
C84.8 Cutaneous T-cell lymphoma, unspecified
0.000 0.323 0.677
K73.9 Chronic hepatitis, unspecified
0.000 0.326 0.674
D61.9 Aplastic anaemia, unspecified
0.000 0.328 0.672
C83.5 Lymphoblastic (diffuse)
0.000 0.331 0.669
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.332 0.668
E12 Malnutrition-related diabetes mellitus
0.000 0.334 0.666
C94 Other leukaemias of specified cell type
0.000 0.339 0.660
E10.0 With coma
0.000 0.340 0.660
E14.3 With ophthalmic complications
0.000 0.340 0.660
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.343 0.657
E16.2 Hypoglycaemia, unspecified
0.000 0.354 0.646
E06.3 Autoimmune thyroiditis
0.000 0.356 0.644
K74.3 Primary biliary cirrhosis
0.000 0.357 0.643
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.357 0.643
K72.0 Acute and subacute hepatic failure
0.000 0.358 0.642
K75.0 Abscess of liver
0.000 0.360 0.640
E10.7 With multiple complications
0.000 0.362 0.638
E24.9 Cushing's syndrome, unspecified
0.000 0.366 0.634
E03.1 Congenital hypothyroidism without goitre
0.000 0.372 0.628
K90 Intestinal malabsorption
0.000 0.375 0.625
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.000 0.378 0.622
E24.0 Pituitary-dependent Cushing's disease
0.000 0.379 0.621
C82.4 Follicular lymphoma grade IIIb
0.000 0.380 0.620
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.618 0.382 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.618 0.382 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.618 0.382 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.618 0.382 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.618 0.382 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.618 0.382 0.000
K75.2 Nonspecific reactive hepatitis
0.000 0.386 0.614
K75.1 Phlebitis of portal vein
0.000 0.386 0.614
E10.2 With renal complications
0.000 0.390 0.610
E13 Other specified diabetes mellitus
0.000 0.392 0.608
I83 Varicose veins of lower extremities
0.607 0.393 0.000
C61 Malignant neoplasm of prostate
0.604 0.396 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.396 0.604
E45 Retarded development following protein-energy malnutrition
0.000 0.396 0.604
E43 Unspecified severe protein-energy malnutrition
0.000 0.396 0.604
E42 Marasmic kwashiorkor
0.000 0.396 0.604
E41 Nutritional marasmus
0.000 0.396 0.604
E40 Kwashiorkor
0.000 0.396 0.604
C83.1 Small cleaved cell (diffuse)
0.000 0.401 0.599
E28 Ovarian dysfunction
0.000 0.403 0.597
C84.0 Mycosis fungoides
0.000 0.404 0.595
C93 Monocytic leukaemia
0.000 0.407 0.593
E10.5 With peripheral circulatory complications
0.000 0.407 0.593
E15 Nondiabetic hypoglycaemic coma
0.000 0.407 0.593
D64.4 Congenital dyserythropoietic anaemia
0.000 0.408 0.592
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.408 0.592
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.408 0.592
M45.X6 Ankylosing spondylitis (Lumbar region)
0.592 0.408 0.000
L40.3 Pustulosis palmaris et plantaris
0.000 0.409 0.591
C84.9 Mature T/NK-cell lymphoma, unspecified
0.000 0.410 0.590
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.000 0.410 0.590
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.000 0.410 0.590
C84.3 Lymphoepithelioid lymphoma
0.000 0.410 0.590
C84.2 T-zone lymphoma
0.000 0.410 0.590
C84.1 Sezary's diease
0.000 0.410 0.590
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.410 0.590
C82.1 Mixed small cleaved and large cell, follicular
0.000 0.414 0.586
E06.5 Other chronic thyroiditis
0.000 0.414 0.586
L40-L45 Papulosquamous disorders
0.000 0.415 0.585
K71.0 Toxic liver disease with cholestasis
0.000 0.415 0.585
K74.6 Other and unspecified cirrhosis of liver
0.000 0.420 0.580
C81.1 Nodular sclerosis
0.000 0.421 0.579
K77 Liver disorders in diseases classified elsewhere
0.000 0.421 0.578
D64.0 Hereditary sideroblastic anaemia
0.000 0.424 0.576
E07.8 Other specified disorders of thyroid
0.000 0.427 0.573
E23 Hypofunction and other disorders of pituitary gland
0.000 0.427 0.573
I83.0 Varicose veins of lower extremities with ulcer
0.566 0.434 0.000
E14.5 With peripheral circulatory complications
0.000 0.437 0.563
E25 Adrenogenital disorders
0.000 0.438 0.562
E26 Hyperaldosteronism
0.000 0.438 0.562
K72.9 Hepatic failure, unspecified
0.000 0.438 0.562
D61.0 Constitutional aplastic anaemia
0.000 0.439 0.561
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.439 0.561
E14.1 With ketoacidosis
0.000 0.444 0.556
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.445 0.555
D64.3 Other sideroblastic anaemias
0.000 0.448 0.552
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.450 0.549
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.450 0.549
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.451 0.548
E32 Diseases of thymus
0.000 0.451 0.548
E31 Polyglandular dysfunction
0.000 0.451 0.548
E30 Disorders of puberty, not elsewhere classified
0.000 0.451 0.548
C85.7 Other specified types of non-Hodgkin's lymphoma
0.000 0.451 0.548
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.453 0.547
E07.9 Disorder of thyroid, unspecified
0.000 0.454 0.546
K74.4 Secondary biliary cirrhosis
0.000 0.454 0.546
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.454 0.546
E06.4 Drug-induced thyroiditis
0.000 0.455 0.545
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.455 0.545
E06.0 Acute thyroiditis
0.000 0.455 0.545
C81.9 Hodgkin's disease, unspecified
0.000 0.456 0.544
E07.1 Dyshormogenetic goitre
0.000 0.459 0.541
E07.0 Hypersecretion of calcitonin
0.000 0.459 0.541
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.463 0.537
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.463 0.537
E16.4 Abnormal secretion of gastrin
0.000 0.463 0.537
E16.3 Increased secretion of glucagon
0.000 0.463 0.537
E24.2 Drug-induced Cushing's syndrome
0.000 0.466 0.534
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.529 0.471 0.000
E28.2 Polycystic ovarian syndrome
0.000 0.472 0.528
K74.5 Biliary cirrhosis, unspecified
0.000 0.474 0.526
L43 Lichen planus
0.000 0.476 0.524
E16.1 Other hypoglycaemia
0.000 0.478 0.522
D61.1 Drug-induced aplastic anaemia
0.000 0.481 0.519
C88.9 Malignant immunoproliferative disease, unspecified
0.000 0.485 0.515
C88.7 Other malignant immunoproliferative diseases
0.000 0.485 0.515
C88.3 Immunoproliferative small intestinal disease
0.000 0.485 0.515
C88.2 Gamma heavy chain disease
0.000 0.485 0.515
C88.1 Alpha heavy chain disease
0.000 0.485 0.515
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
C92 Myeloid leukaemia
0.000 0.486 0.513
D61.8 Other specified aplastic anaemias
0.000 0.487 0.513
D61.3 Idiopathic aplastic anaemia
0.000 0.487 0.513
D61.2 Aplastic anaemia due to other external agents
0.000 0.487 0.513
E14.7 With multiple complications
0.000 0.487 0.513
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.487 0.512
E24.3 Ectopic ACTH syndrome
0.000 0.487 0.512
E24.1 Nelson's syndrome
0.000 0.487 0.512
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.000 0.489 0.511
C96.8 Histiocytic sarcoma
0.000 0.489 0.511
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.489 0.511
C96.6 Unifocal Langerhans-cell histiocytosis
0.000 0.489 0.511
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.000 0.489 0.511
C96.4 Sarcoma of dendritic cells (accessory cells)
0.000 0.489 0.511
C96.3 True histiocytic lymphoma
0.000 0.489 0.511
C96.2 Malignant mast cell tumour
0.000 0.489 0.511
C96.1 Malignant histiocytosis
0.000 0.489 0.511
C96.0 Letterer-Siwe disease
0.000 0.489 0.511
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.000 0.491 0.509
C86.4 Blastic NK-cell lymphoma
0.000 0.491 0.509
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.000 0.491 0.509
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.000 0.491 0.509
C86.1 Hepatosplenic T-cell lymphoma
0.000 0.491 0.509
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.000 0.491 0.509
C86.5 Angioimmunoblastic T-cell lymphoma
0.000 0.493 0.507
E14.4 With neurological complications
0.000 0.494 0.506
K71.1 Toxic liver disease with hepatic necrosis
0.000 0.499 0.501
E14.6 With other specified complications
0.000 0.501 0.499
E14.0 With coma
0.000 0.501 0.499
D64.8 Other specified anaemias
0.000 0.501 0.499
E05.8 Other thyrotoxicosis
0.001 0.502 0.498
E24.8 Other Cushing's syndrome
0.000 0.502 0.498
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.502 0.498
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.000 0.503 0.497
C81.3 Lymphocytic depletion
0.000 0.503 0.497
E14.8 With unspecified complications
0.000 0.505 0.495
K72.1 Chronic hepatic failure
0.000 0.507 0.493
C84.4 Peripheral T-cell lymphoma
0.000 0.507 0.492
C95 Leukaemia of unspecified cell type
0.000 0.509 0.490
E23.2 Diabetes insipidus
0.000 0.511 0.489
E27 Other disorders of adrenal gland
0.000 0.511 0.489
K71.8 Toxic liver disease with other disorders of liver
0.000 0.514 0.486
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver
0.000 0.514 0.486
K71.5 Toxic liver disease with chronic active hepatitis
0.000 0.514 0.486
K71.4 Toxic liver disease with chronic lobular hepatitis
0.000 0.514 0.486
K71.3 Toxic liver disease with chronic persistent hepatitis
0.000 0.514 0.486
K71.2 Toxic liver disease with acute hepatitis
0.000 0.514 0.486
K71.6 Toxic liver disease with hepatitis, not elsewhere classified
0.000 0.515 0.485
L43.9 Lichen planus, unspecified
0.000 0.518 0.482
E06.1 Subacute thyroiditis
0.000 0.520 0.480
E20 Hypoparathyroidism
0.000 0.522 0.478
E12.9 Without complications
0.000 0.522 0.478
E12.8 With unspecified complications
0.000 0.522 0.478
E12.7 With multiple complications
0.000 0.522 0.478
E12.6 With other specified complications
0.000 0.522 0.478
E12.5 With peripheral circulatory complications
0.000 0.522 0.478
E12.4 With neurological complications
0.000 0.522 0.478
E12.3 With ophthalmic complications
0.000 0.522 0.478
E12.2 With renal complications
0.000 0.522 0.478
E12.1 With ketoacidosis
0.000 0.522 0.478
E12.0 With coma
0.000 0.522 0.478
E21.4 Other specified disorders of parathyroid gland
0.000 0.523 0.477
E21.0 Primary hyperparathyroidism
0.000 0.525 0.475
K71.9 Toxic liver disease, unspecified
0.000 0.526 0.474
C94.7 Other specified leukaemias
0.000 0.526 0.473
C94.5 Acute myelofibrosis
0.000 0.526 0.473
C94.4 Acute panmyelosis
0.000 0.526 0.473
C94.3 Mast cell leukaemia
0.000 0.526 0.473
C94.2 Acute megakaryoblastic leukaemia
0.000 0.526 0.473
C94.1 Chronic erythraemia
0.000 0.526 0.473
C94.0 Acute erythraemia and erythroleukaemia
0.000 0.526 0.473
C91 Lymphoid leukaemia
0.000 0.527 0.473
K90.9 Intestinal malabsorption, unspecified
0.000 0.528 0.472
E21.2 Other hyperparathyroidism
0.000 0.529 0.471
E10.4 With neurological complications
0.000 0.531 0.469
E14.2 Withrenal complications
0.000 0.535 0.465
E06.9 Thyroiditis, unspecified
0.000 0.543 0.456
K90.3 Pancreatic steatorrhoea
0.000 0.552 0.448
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.552 0.448
K90.1 Tropical sprue
0.000 0.552 0.448
C81.0 Lymphocytic predominance
0.000 0.558 0.441
C92.1 Chronic myeloid leukaemia
0.000 0.559 0.441
E13.3 With ophthalmic complications
0.000 0.562 0.437
E23.6 Other disorders of pituitary gland
0.000 0.563 0.437
E23.7 Disorder of pituitary gland, unspecified
0.000 0.564 0.436
E13.8 With unspecified complications
0.000 0.564 0.436
E13.7 With multiple complications
0.000 0.564 0.436
E13.6 With other specified complications
0.000 0.564 0.436
E13.5 With peripheral circulatory complications
0.000 0.564 0.436
E13.4 With neurological complications
0.000 0.564 0.436
E13.2 With renal complications
0.000 0.564 0.436
E13.1 With ketoacidosis
0.000 0.564 0.436
E13.0 With coma
0.000 0.564 0.436
E44.1 Mild protein-energy malnutrition
0.000 0.567 0.433
E44.0 Moderate protein-energy malnutrition
0.000 0.567 0.433
C81.2 Mixed cellularity
0.000 0.571 0.428
E28.9 Ovarian dysfunction, unspecified
0.000 0.572 0.428
E28.8 Other ovarian dysfunction
0.000 0.572 0.428
E28.1 Androgen excess
0.000 0.572 0.428
E28.0 Oestrogen excess
0.000 0.572 0.428
C93.9 Monocytic leukaemia, unspecified
0.000 0.574 0.425
C93.7 Other monocytic leukaemia
0.000 0.574 0.425
C93.3 Juvenile myelomonocytic leukaemia
0.000 0.574 0.425
C93.2 Subacute monocytic leukaemia
0.000 0.574 0.425
C93.0 Acute monocytic leukaemia
0.000 0.574 0.425
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.000 0.578 0.421
C90 Multiple myeloma and malignant plasma cell neoplasms
0.000 0.578 0.421
C91.9 Lymphoid leukaemia, unspecified
0.000 0.578 0.422
D60.9 Acquired pure red cell aplasia, unspecified
0.000 0.580 0.420
L44 Other papulosquamous disorders
0.000 0.580 0.420
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.580 0.420
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.583 0.417
E26.0 Primary hyperaldosteronism
0.000 0.585 0.415
K77.8 Liver disorders in other diseases classified elsewhere
0.000 0.585 0.415
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere
0.000 0.585 0.415
C81.7 Other Hodgkin's disease
0.000 0.585 0.414
E27.9 Disorder of adrenal gland, unspecified
0.000 0.587 0.413
K74.1 Hepatic sclerosis
0.000 0.588 0.412
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.589 0.411
E23.1 Drug-induced hypopituitarism
0.000 0.589 0.411
E26.9 Hyperaldosteronism, unspecified
0.000 0.595 0.405
E25.9 Adrenogenital disorder, unspecified
0.000 0.597 0.403
E25.8 Other adrenogenital disorders
0.000 0.597 0.403
E26.8 Other hyperaldosteronism
0.000 0.597 0.403
E26.1 Secondary hyperaldosteronism
0.000 0.597 0.403
D60.8 Other acquired pure red cell aplasias
0.000 0.597 0.402
D60.1 Transient acquired pure red cell aplasia
0.000 0.597 0.402
D60.0 Chronic acquired pure red cell aplasia
0.000 0.597 0.402
E27.1 Primary adrenocortical insufficiency
0.000 0.606 0.394
E30.9 Disorder of puberty, unspecified
0.000 0.606 0.393
E30.8 Other disorders of puberty
0.000 0.606 0.393
E30.1 Precocious puberty
0.000 0.606 0.393
E30.0 Delayed puberty
0.000 0.606 0.393
E31.9 Polyglandular dysfunction, unspecified
0.000 0.606 0.393
E31.8 Other polyglandular dysfunction
0.000 0.606 0.393
E31.1 Polyglandular hyperfunction
0.000 0.606 0.393
E31.0 Autoimmune polyglandular failure
0.000 0.606 0.393
E32.9 Disease of thymus, unspecified
0.000 0.606 0.393
E32.8 Other diseases of thymus
0.000 0.606 0.393
E32.1 Abscess of thymus
0.000 0.606 0.393
E32.0 Persistent hyperplasia of thymus
0.000 0.606 0.393
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.606 0.393
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.606 0.393
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.606 0.393
L42 Pityriasis rosea
0.000 0.610 0.390
L41 Parapsoriasis
0.000 0.610 0.390
L43.3 Subacute (active) lichen planus
0.000 0.624 0.376
L43.2 Lichenoid drug reaction
0.000 0.624 0.376
L43.1 Bullous lichen planus
0.000 0.624 0.376
L43.0 Hypertrophic lichen planus
0.000 0.624 0.376
E13.9 Without complications
0.000 0.625 0.375
K90.8 Other intestinal malabsorption
0.000 0.629 0.371
C92.9 Myeloid leukaemia, unspecified
0.000 0.631 0.369
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.000 0.632 0.368
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.000 0.632 0.368
C92.3 Myeloid sarcoma
0.000 0.632 0.368
C92.2 Subacute myeloid leukaemia
0.000 0.632 0.368
L43.8 Other lichen planus
0.000 0.632 0.368
E83 Disorders of mineral metabolism
0.367 0.633 0.000
C92.5 Acute myelomonocytic leukaemia
0.000 0.642 0.358
C95.7 Other leukaemia of unspecified cell type
0.000 0.648 0.351
C95.2 Subacute leukaemia of unspecified cell type
0.000 0.648 0.351
E27.5 Adrenomedullary hyperfunction
0.000 0.649 0.350
E27.0 Other adrenocortical overactivity
0.000 0.649 0.350
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.657 0.343
E20.8 Other hypoparathyroidism
0.000 0.657 0.343
E20.1 Pseudohypoparathyroidism
0.000 0.657 0.343
E20.0 Idiopathic hypoparathyroidism
0.000 0.657 0.343
C90.3 Solitary plasmacytoma
0.000 0.657 0.343
C91.8 Mature B-cell leukaemia Burkitt-type
0.000 0.661 0.339
C91.7 Other lymphoid leukaemia
0.000 0.661 0.339
C91.6 Prolymphocytic leukaemia of T-cell type
0.000 0.661 0.339
C91.3 Prolymphocytic leukaemia
0.000 0.661 0.339
C91.2 Subacute lymphocytic leukaemia
0.000 0.661 0.339
C91.5 Adult T-cell leukaemia
0.000 0.664 0.336
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.665 0.335
K70 Alcoholic liver disease
0.000 0.667 0.333
E83.3 Disorders of phosphorus metabolism
0.331 0.669 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.675 0.325
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.001 0.680 0.319
C92.4 Acute promyelocytic leukaemia
0.000 0.687 0.313
C90.1 Plasma cell leukaemia
0.000 0.688 0.312
E27.2 Addisonian crisis
0.000 0.691 0.309
C95.1 Chronic leukaemia of unspecified cell type
0.001 0.692 0.307
E28.3 Primary ovarian failure
0.000 0.693 0.307
C93.1 Chronic monocytic leukaemia
0.001 0.694 0.306
C88.0 Waldenstrom's macroglobulinaemia
0.001 0.695 0.304
L44.9 Papulosquamous disorder, unspecified
0.000 0.699 0.301
L44.8 Other specified papulosquamous disorders
0.000 0.699 0.301
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.699 0.301
L44.3 Lichen ruber moniliformis
0.000 0.699 0.301
L44.2 Lichen striatus
0.000 0.699 0.301
L44.1 Lichen nitidus
0.000 0.699 0.301
L44.0 Pityriasis rubra pilaris
0.000 0.699 0.301
Z85.4 Personal history of malignant neoplasm of genital organs
0.299 0.701 0.000
C95.9 Leukaemia, unspecified
0.001 0.702 0.297
E29 Testicular dysfunction
0.002 0.703 0.295
C95.0 Acute leukaemia of unspecified cell type
0.001 0.706 0.293
E83.9 Disorder of mineral metabolism, unspecified
0.293 0.707 0.000
K70.4 Alcoholic hepatic failure
0.000 0.711 0.289
E34 Other endocrine disorders
0.001 0.712 0.287
L41.9 Parapsoriasis, unspecified
0.000 0.720 0.279
L41.8 Other parapsoriasis
0.000 0.720 0.279
L41.5 Retiform parapsoriasis
0.000 0.720 0.279
L41.4 Large plaque parapsoriasis
0.000 0.720 0.279
L41.3 Small plaque parapsoriasis
0.000 0.720 0.279
L41.2 Lymphomatoid papulosis
0.000 0.720 0.279
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.720 0.279
E22 Hyperfunction of pituitary gland
0.000 0.727 0.273
E20.9 Hypoparathyroidism, unspecified
0.000 0.728 0.272
E65-E68 Obesity and other hyperalimentation
0.000 0.728 0.272
E83.8 Other disorders of mineral metabolism
0.263 0.737 0.000
E83.2 Disorders of zinc metabolism
0.263 0.737 0.000
E83.0 Disorders of copper metabolism
0.263 0.737 0.000
C92.7 Other myeloid leukaemia
0.001 0.742 0.257
L41.1 Pityriasis lichenoides chronica
0.000 0.750 0.249
K70.0 Alcoholic fatty liver
0.000 0.750 0.249
C92.0 Acute myeloid leukaemia
0.000 0.755 0.245
C83.0 Small cell (diffuse)
0.002 0.755 0.243
D63.1 Anaemia in other chronic diseases classified elsewhere
0.000 0.759 0.241
C91.4 Hairy-cell leukaemia
0.000 0.769 0.231
E34.3 Short stature, not elsewhere classified
0.001 0.776 0.223
C91.0 Acute lymphoblastic leukaemia
0.000 0.777 0.223
C90.2 Plasmacytoma, extramedullary
0.000 0.784 0.216
K70.1 Alcoholic hepatitis
0.000 0.784 0.216
E29.8 Other testicular dysfunction
0.001 0.787 0.212
E29.0 Testicular hyperfunction
0.001 0.787 0.212
E34.5 Androgen resistance syndrome
0.001 0.793 0.206
E34.4 Constitutional tall stature
0.001 0.793 0.206
E34.2 Ectopic hormone secretion, not elsewhere classified
0.001 0.793 0.206
E34.1 Other hypersecretion of intestinal hormones
0.001 0.793 0.206
I83.1 Varicose veins of lower extremities with inflammation
0.200 0.800 0.000
E22.8 Other hyperfunction of pituitary gland
0.000 0.804 0.196
E67 Other hyperalimentation
0.000 0.805 0.195
E68 Sequelae of hyperalimentation
0.000 0.805 0.195
E23.0 Hypopituitarism
0.000 0.805 0.195
C91.1 Chronic lymphocytic leukaemia
0.000 0.805 0.195
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.807 0.193
C60-C63 Malignant neoplasms of male genital organs
0.180 0.817 0.004
K70.2 Alcoholic fibrosis and sclerosis of liver
0.000 0.819 0.181
E29.9 Testicular dysfunction, unspecified
0.002 0.819 0.180
D63.8 Anaemia in other chronic diseases classified elsewhere
0.000 0.820 0.180
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.825 0.174
E50-E64 Other nutritional deficiencies
0.000 0.826 0.173
E34.9 Endocrine disorder, unspecified
0.001 0.829 0.170
E34.8 Other specified endocrine disorders
0.001 0.834 0.164
K70.9 Alcoholic liver disease, unspecified
0.000 0.836 0.164
K76 Other diseases of liver
0.000 0.837 0.163
E27.8 Other specified disorders of adrenal gland
0.001 0.838 0.161
E04 Other non-toxic goitre
0.000 0.839 0.161
E22.1 Hyperprolactinaemia
0.000 0.840 0.159
D63.0 Anaemia in neoplastic disease
0.000 0.850 0.150
C63 Malignant neoplasm of other and unspecified male genital organs
0.143 0.854 0.002
E83.4 Disorders of magnesium metabolism
0.145 0.855 0.000
E67.8 Other specified hyperalimentation
0.000 0.860 0.140
E67.3 Hypervitaminosis D
0.000 0.860 0.140
E67.2 Megavitamin-B6 syndrome
0.000 0.860 0.140
E67.1 Hypercarotenaemia
0.000 0.860 0.140
E67.0 Hypervitaminosis A
0.000 0.860 0.140
K76.9 Liver disease, unspecified
0.000 0.860 0.140
E04.0 Non-toxic diffuse goitre
0.000 0.863 0.137
E51 Thiamine deficiency
0.000 0.869 0.130
E65 Localised adiposity
0.001 0.871 0.129
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.875 0.124
E50 Vitamin A deficiency
0.000 0.875 0.124
E60 Dietary zinc deficiency
0.000 0.875 0.124
E59 Dietary selenium deficiency
0.000 0.875 0.124
E52 Niacin deficiency [pellagra]
0.000 0.875 0.124
E56 Other vitamin deficiencies
0.000 0.876 0.124
E11 Non-insulin-dependent diabetes mellitus
0.000 0.877 0.123
E63 Other nutritional deficiencies
0.000 0.878 0.122
Z51.3 Blood transfusion without reported diagnosis
0.000 0.881 0.119
C63.2 Scrotum
0.117 0.881 0.001
C60 Malignant neoplasm of penis
0.115 0.882 0.003
K76.5 Hepatic veno-occlusive disease
0.000 0.883 0.117
K76.4 Peliosis hepatis
0.000 0.883 0.117
K76.3 Infarction of liver
0.000 0.883 0.117
K76.2 Central haemorrhagic necrosis of liver
0.000 0.883 0.117
K76.7 Hepatorenal syndrome
0.000 0.884 0.116
E04.8 Other specified non-toxic goitre
0.000 0.884 0.116
E14.9 Without complications
0.000 0.886 0.114
E58 Dietary calcium deficiency
0.000 0.887 0.113
E11.1 With ketoacidosis
0.000 0.889 0.111
K70.3 Alcoholic cirrhosis of liver
0.000 0.890 0.110

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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