TreeWAS – Variant ID: rs1265097

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
K90.0 Coeliac disease	0.000	0.000	1.000
J45.9 Asthma, unspecified	0.000	0.002	0.998
I20-I25 Ischaemic heart diseases	0.977	0.023	0.000
I20 Angina pectoris	0.976	0.024	0.000
I25 Chronic ischaemic heart disease	0.968	0.032	0.000
I20.9 Angina pectoris, unspecified	0.966	0.034	0.000
I25.1 Atherosclerotic heart disease	0.963	0.037	0.000
I21 Acute myocardial infarction	0.958	0.042	0.000
I20.0 Unstable angina	0.955	0.045	0.000
I21.9 Acute myocardial infarction, unspecified	0.942	0.058	0.000
E10.9 Without complications	0.000	0.085	0.915
E10 Insulin-dependent diabetes mellitus	0.000	0.096	0.904
J45 Asthma	0.017	0.126	0.857
I21.0 Acute transmural myocardial infarction of anterior wall	0.859	0.141	0.000
I22 Subsequent myocardial infarction	0.858	0.142	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.840	0.160	0.000
E10-E14 Diabetes mellitus	0.005	0.162	0.833
E10.3 With ophthalmic complications	0.000	0.175	0.825
J45.0 Predominantly allergic asthma	0.003	0.177	0.821
E14 Unspecified diabetes mellitus	0.002	0.188	0.811
I22.1 Subsequent myocardial infarction of inferior wall	0.805	0.195	0.000
E14.9 Without complications	0.000	0.210	0.790
I23 Certain current complications following acute myocardial infarction	0.761	0.239	0.000
I25.3 Aneurysm of heart	0.758	0.242	0.000
I25.5 Ischaemic cardiomyopathy	0.754	0.246	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.742	0.258	0.000
E10.1 With ketoacidosis	0.000	0.260	0.740
E10.4 With neurological complications	0.000	0.270	0.730
I25.6 Silent myocardial ischaemia	0.694	0.306	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.694	0.306	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.687	0.313	0.000
E03 Other hypothyroidism	0.680	0.319	0.001
I25.8 Other forms of chronic ischaemic heart disease	0.679	0.321	0.000
E14.3 With ophthalmic complications	0.001	0.327	0.672
E10.5 With peripheral circulatory complications	0.000	0.338	0.662
I20.1 Angina pectoris with documented spasm	0.661	0.339	0.000
E10.2 With renal complications	0.000	0.350	0.650
I21.2 Acute transmural myocardial infarction of other sites	0.648	0.352	0.000
E10.8 With unspecified complications	0.000	0.352	0.648
E10.7 With multiple complications	0.000	0.352	0.648
E10.6 With other specified complications	0.000	0.352	0.648
E10.0 With coma	0.000	0.352	0.648
I24 Other acute ischaemic heart diseases	0.643	0.357	0.000
E13 Other specified diabetes mellitus	0.003	0.366	0.630
J45.8 Mixed asthma	0.012	0.373	0.614
J45.1 Nonallergic asthma	0.012	0.373	0.614
I21.3 Acute transmural myocardial infarction of unspecified site	0.611	0.389	0.000
I25.4 Coronary artery aneurysm	0.607	0.393	0.000
I23.8 Other current complications following acute myocardial infarction	0.606	0.394	0.000
E12 Malnutrition-related diabetes mellitus	0.004	0.399	0.597
I20.8 Other forms of angina pectoris	0.594	0.406	0.000
I22.8 Subsequent myocardial infarction of other sites	0.587	0.413	0.000
K90 Intestinal malabsorption	0.000	0.415	0.585
E14.7 With multiple complications	0.001	0.418	0.581
E14.6 With other specified complications	0.001	0.418	0.581
E14.5 With peripheral circulatory complications	0.001	0.418	0.581
E14.4 With neurological complications	0.001	0.418	0.581
E14.2 Withrenal complications	0.001	0.418	0.581
E14.1 With ketoacidosis	0.001	0.418	0.581
E14.0 With coma	0.001	0.418	0.581
I22.0 Subsequent myocardial infarction of anterior wall	0.572	0.428	0.000
E11 Non-insulin-dependent diabetes mellitus	0.000	0.431	0.569
E78.0 Pure hypercholesterolaemia	0.563	0.437	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.561	0.439	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.546	0.454	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.546	0.454	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.546	0.454	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.546	0.454	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.546	0.454	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.546	0.454	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.546	0.454	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.544	0.456	0.000
E00-E07 Disorders of thyroid gland	0.539	0.460	0.001
E14.8 With unspecified complications	0.002	0.484	0.514
E11.1 With ketoacidosis	0.000	0.488	0.511
K90.9 Intestinal malabsorption, unspecified	0.000	0.493	0.507
E03.5 Myxoedema coma	0.487	0.512	0.001
E03.4 Atrophy of thyroid (acquired)	0.487	0.512	0.001
E03.3 Postinfectious hypothyroidism	0.487	0.512	0.001
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.487	0.512	0.001
E03.1 Congenital hypothyroidism without goitre	0.487	0.512	0.001
E03.0 Congenital hypothyroidism with diffuse goitre	0.487	0.512	0.001
E11.5 With peripheral circulatory complications	0.000	0.513	0.487
E13.9 Without complications	0.002	0.513	0.485
Chapter IV Endocrine, nutritional and metabolic diseases	0.479	0.513	0.007
E06 Thyroiditis	0.482	0.518	0.001
E11.4 With neurological complications	0.000	0.536	0.464
I24.1 Dressler's syndrome	0.461	0.539	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.460	0.540	0.000
E13.8 With unspecified complications	0.003	0.546	0.452
E13.7 With multiple complications	0.003	0.546	0.452
E13.6 With other specified complications	0.003	0.546	0.452
E13.5 With peripheral circulatory complications	0.003	0.546	0.452
E13.4 With neurological complications	0.003	0.546	0.452
E13.3 With ophthalmic complications	0.003	0.546	0.452
E13.2 With renal complications	0.003	0.546	0.452
E13.1 With ketoacidosis	0.003	0.546	0.452
E13.0 With coma	0.003	0.546	0.452
E70-E90 Metabolic disorders	0.437	0.562	0.001
E12.9 Without complications	0.003	0.569	0.428
E12.8 With unspecified complications	0.003	0.569	0.428
E12.7 With multiple complications	0.003	0.569	0.428
E12.6 With other specified complications	0.003	0.569	0.428
E12.5 With peripheral circulatory complications	0.003	0.569	0.428
E12.4 With neurological complications	0.003	0.569	0.428
E12.3 With ophthalmic complications	0.003	0.569	0.428
E12.2 With renal complications	0.003	0.569	0.428
E12.1 With ketoacidosis	0.003	0.569	0.428
E12.0 With coma	0.003	0.569	0.428
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.431	0.569	0.000
# Top node	0.430	0.570	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.429	0.571	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.424	0.576	0.000
E11.3 With ophthalmic complications	0.000	0.579	0.421
K90.8 Other intestinal malabsorption	0.000	0.580	0.419
K90.3 Pancreatic steatorrhoea	0.000	0.580	0.419
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.580	0.419
K90.1 Tropical sprue	0.000	0.580	0.419
Chapter IX Diseases of the circulatory system	0.419	0.581	0.000
T91 Sequelae of injuries of neck and trunk	0.418	0.582	0.000
E06.3 Autoimmune thyroiditis	0.415	0.585	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.412	0.588	0.000
E11.8 With unspecified complications	0.000	0.589	0.411
E11.7 With multiple complications	0.000	0.592	0.408
Q20-Q28 Congenital malformations of the circulatory system	0.408	0.592	0.000
Chapter XX External causes of morbidity and mortality	0.401	0.599	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.401	0.599	0.000
Q80-Q89 Other congenital malformations	0.399	0.601	0.000
E06.9 Thyroiditis, unspecified	0.398	0.601	0.000
J40-J47 Chronic lower respiratory diseases	0.381	0.604	0.015
L43.9 Lichen planus, unspecified	0.396	0.604	0.000
I21.4 Acute subendocardial myocardial infarction	0.395	0.605	0.000
Q50-Q56 Congenital malformations of genital organs	0.394	0.606	0.000
Chapter V Mental and behavioural disorders	0.392	0.608	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.391	0.609	0.000
L43 Lichen planus	0.389	0.611	0.000
Chapter X Diseases of the respiratory system	0.388	0.611	0.001
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.387	0.612	0.001
E00 Congenital iodine-deficiency syndrome	0.387	0.612	0.001
E02 Subclinical iodine-deficiency hypothyroidism	0.387	0.612	0.001
J32.9 Chronic sinusitis, unspecified	0.387	0.613	0.000
J30-J39 Other diseases of upper respiratory tract	0.385	0.615	0.000
J32 Chronic sinusitis	0.383	0.617	0.000
F30-F39 Mood [affective] disorders	0.383	0.617	0.000
S40-S49 Injuries to the shoulder and upper arm	0.381	0.619	0.000
L40-L45 Papulosquamous disorders	0.381	0.619	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.381	0.619	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.380	0.620	0.000
J47 Bronchiectasis	0.380	0.620	0.000
E11.6 With other specified complications	0.000	0.625	0.374
T42.4 Benzodiazepines	0.374	0.626	0.000
Y57 Other and unspecified drugs and medicaments	0.373	0.627	0.000
T91.3 Sequelae of injury of spinal cord	0.372	0.628	0.000
T91.1 Sequelae of fracture of spine	0.372	0.628	0.000
Q25 Congenital malformations of great arteries	0.371	0.629	0.000
J35 Chronic diseases of tonsils and adenoids	0.371	0.629	0.000
F33 Recurrent depressive disorder	0.371	0.629	0.000
Y57.9 Drug or medicament, unspecified	0.370	0.630	0.000
Q23 Congenital malformations of aortic and mitral valves	0.369	0.631	0.000
E03.8 Other specified hypothyroidism	0.366	0.633	0.001
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.367	0.633	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.365	0.635	0.000
E07 Other disorders of thyroid	0.362	0.637	0.001
J42 Unspecified chronic bronchitis	0.358	0.638	0.004
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.360	0.640	0.000
Q54 Hypospadias	0.359	0.641	0.000
E78.4 Other hyperlipidaemia	0.357	0.643	0.000
J35.0 Chronic tonsillitis	0.356	0.644	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.645	0.354
T91.2 Sequelae of other fracture of thorax and pelvis	0.354	0.646	0.000
J31.0 Chronic rhinitis	0.354	0.646	0.000
S10-S19 Injuries to the neck	0.352	0.648	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.349	0.651	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.348	0.652	0.000
E40-E46 Malnutrition	0.342	0.653	0.005
E06.5 Other chronic thyroiditis	0.346	0.654	0.001
E06.4 Drug-induced thyroiditis	0.346	0.654	0.001
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.346	0.654	0.001
E06.1 Subacute thyroiditis	0.346	0.654	0.001
E06.0 Acute thyroiditis	0.346	0.654	0.001
F60-F69 Disorders of adult personality and behaviour	0.345	0.655	0.000
F80-F89 Disorders of psychological development	0.344	0.656	0.000
Q23.1 Congenital insufficiency of aortic valve	0.341	0.659	0.000
T90 Sequelae of injuries of head	0.340	0.660	0.000
S50-S59 Injuries to the elbow and forearm	0.339	0.661	0.000
V10-V19 Pedal cyclist injured in transport accident	0.338	0.662	0.000
T79-T79 Certain early complications of trauma	0.338	0.662	0.000
J35.8 Other chronic diseases of tonsils and adenoids	0.338	0.662	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.337	0.663	0.000
S42 Fracture of shoulder and upper arm	0.336	0.664	0.000
F33.9 Recurrent depressive disorder, unspecified	0.336	0.664	0.000
E65-E68 Obesity and other hyperalimentation	0.332	0.666	0.003
T20-T25 Burns and corrosions of external body surface, specified by site	0.333	0.667	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.330	0.669	0.000
E78.6 Lipoprotein deficiency	0.330	0.670	0.000
E78.3 Hyperchylomicronaemia	0.330	0.670	0.000
E78.1 Pure hyperglyceridaemia	0.330	0.670	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.330	0.670	0.000
Q25.1 Coarctation of aorta	0.330	0.670	0.000
E20-E35 Disorders of other endocrine glands	0.325	0.671	0.004
W50-W64 Exposure to animate mechanical forces	0.329	0.671	0.000
T91.9 Sequelae of unspecified injury of neck and trunk	0.329	0.671	0.000
X10-X19 Contact with heat and hot substances	0.328	0.671	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.328	0.672	0.000
T91.8 Sequelae of other specified injuries of neck and trunk	0.327	0.673	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.327	0.673	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.327	0.673	0.000
J40 Bronchitis, not specified as acute or chronic	0.323	0.674	0.004
T93 Sequelae of injuries of lower limb	0.326	0.674	0.000
E11.2 With renal complications	0.000	0.674	0.325
I24.8 Other forms of acute ischaemic heart disease	0.325	0.675	0.000
F30 Manic episode	0.324	0.676	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.324	0.676	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.323	0.677	0.000
Chapter II Neoplasms	0.323	0.677	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.322	0.678	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.322	0.678	0.000
Q60-Q64 Congenital malformations of the urinary system	0.320	0.679	0.000
Q00-Q07 Congenital malformations of the nervous system	0.320	0.680	0.000
T36 Poisoning by systemic antibiotics	0.320	0.680	0.000
T00-T07 Injuries involving multiple body regions	0.320	0.680	0.000
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.318	0.682	0.000
E50-E64 Other nutritional deficiencies	0.314	0.682	0.004
X20-X29 Contact with venomous animals and plants	0.318	0.682	0.000
Q83 Congenital malformations of breast	0.317	0.683	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.316	0.683	0.000
J32.2 Chronic ethmoidal sinusitis	0.316	0.684	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.316	0.684	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.315	0.685	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.314	0.685	0.001
F39 Unspecified mood [affective] disorder	0.315	0.685	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.315	0.685	0.000
L43.8 Other lichen planus	0.314	0.686	0.000
T66-T78 Other and unspecified effects of external causes	0.314	0.686	0.000
Q89 Other congenital malformations, not elsewhere classified	0.314	0.686	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.314	0.686	0.000
E84 Cystic fibrosis	0.313	0.686	0.001
E79 Disorders of purine and pyrimidine metabolism	0.313	0.686	0.001
E77 Disorders of glycoprotein metabolism	0.313	0.686	0.001
E76 Disorders of glycosaminoglycan metabolism	0.313	0.686	0.001
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.313	0.686	0.001
E72 Other disorders of amino-acid metabolism	0.313	0.686	0.001
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.313	0.686	0.001
E70 Disorders of aromatic amino-acid metabolism	0.313	0.686	0.001
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.313	0.686	0.001
E74 Other disorders of carbohydrate metabolism	0.313	0.686	0.001
Q54.1 Hypospadias, penile	0.313	0.687	0.000
C44 Other malignant neoplasms of skin	0.312	0.688	0.000
F60 Specific personality disorders	0.312	0.688	0.000
C44.3 Skin of other and unspecified parts of face	0.311	0.689	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.310	0.689	0.000
I05-I09 Chronic rheumatic heart diseases	0.310	0.690	0.000
W00-W19 Falls	0.310	0.690	0.000
Q87.4 Marfan's syndrome	0.310	0.690	0.000
Y40 Systemic antibiotics	0.309	0.691	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.309	0.691	0.000
Q35-Q37 Cleft lip and cleft palate	0.309	0.691	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.309	0.691	0.000
J32.8 Other chronic sinusitis	0.309	0.691	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.309	0.691	0.000
Y48 Anaesthetics and therapeutic gases	0.308	0.692	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.308	0.692	0.000
T33-T35 Frostbite	0.307	0.693	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.307	0.693	0.000
F84 Pervasive developmental disorders	0.307	0.693	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.306	0.693	0.000
Q25.4 Other congenital malformations of aorta	0.306	0.694	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.305	0.695	0.000
T95 Sequelae of burns, corrosions and frostbite	0.304	0.696	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.304	0.696	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.304	0.696	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.304	0.696	0.000
T42.1 Iminostilbenes	0.303	0.696	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.302	0.698	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.302	0.698	0.000
S20-S29 Injuries to the thorax	0.302	0.698	0.000
V01-V09 Pedestrian injured in transport accident	0.301	0.699	0.000
I00-I02 Acute rheumatic fever	0.301	0.699	0.000
S42.0 Fracture of clavicle	0.300	0.700	0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.300	0.700	0.000
T91.4 Sequelae of injury of intrathoracic organs	0.300	0.700	0.000
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.300	0.700	0.000
S40 Superficial injury of shoulder and upper arm	0.299	0.701	0.000
Q28 Other congenital malformations of circulatory system	0.298	0.702	0.000
E21.0 Primary hyperparathyroidism	0.297	0.703	0.000
C44.2 Skin of ear and external auricular canal	0.297	0.703	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.297	0.703	0.000
Q54.0 Hypospadias, balanic	0.296	0.703	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.296	0.704	0.000
T59 Toxic effect of other gases, fumes and vapours	0.296	0.704	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.296	0.704	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.295	0.704	0.000
F70-F79 Mental retardation	0.295	0.705	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.295	0.705	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.295	0.705	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.295	0.705	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.295	0.705	0.000
E11.0 With coma	0.001	0.705	0.294
V20-V29 Motorcycle rider injured in transport accident	0.294	0.706	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.293	0.706	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.293	0.707	0.000
Q27 Other congenital malformations of peripheral vascular system	0.293	0.707	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.293	0.707	0.000
L42 Pityriasis rosea	0.293	0.707	0.000
Q24 Other congenital malformations of heart	0.293	0.707	0.000
S42.1 Fracture of scapula	0.293	0.707	0.000
Q26 Congenital malformations of great veins	0.292	0.707	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.292	0.707	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.292	0.707	0.000
T98 Sequelae of other and unspecified effects of external causes	0.292	0.708	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.292	0.708	0.000
T92 Sequelae of injuries of upper limb	0.292	0.708	0.000
S11 Open wound of neck	0.290	0.710	0.000
S41 Open wound of shoulder and upper arm	0.289	0.711	0.000
J37 Chronic laryngitis and laryngotracheitis	0.288	0.711	0.000
W20-W49 Exposure to inanimate mechanical forces	0.288	0.712	0.000
Y35-Y36 Legal intervention and operations of war	0.288	0.712	0.000
Y10-Y34 Event of undetermined intent	0.288	0.712	0.000
X85-X99 Assault	0.288	0.712	0.000
X30-X39 Exposure to forces of nature	0.288	0.712	0.000
X00-X09 Exposure to smoke, fire and flames	0.288	0.712	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.288	0.712	0.000
W75-W84 Other accidental threats to breathing	0.288	0.712	0.000
W65-W74 Accidental drowning and submersion	0.288	0.712	0.000
V98-V99 Other and unspecified transport accidents	0.288	0.712	0.000
V95-V97 Air and space transport accidents	0.288	0.712	0.000
V90-V94 Water transport accidents	0.288	0.712	0.000
V70-V79 Bus occupant injured in transport accident	0.288	0.712	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.288	0.712	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.288	0.712	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.288	0.712	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.288	0.712	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.288	0.712	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.288	0.712	0.000
T42.3 Barbiturates	0.288	0.712	0.000
T42.2 Succinimides and oxazolidinediones	0.288	0.712	0.000
T42.0 Hydantoin derivatives	0.288	0.712	0.000
E65 Localised adiposity	0.286	0.713	0.001
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.287	0.713	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.286	0.713	0.000
Q84 Other congenital malformations of integument	0.286	0.713	0.000
Q81 Epidermolysis bullosa	0.286	0.713	0.000
Q80 Congenital ichthyosis	0.286	0.713	0.000
V80-V89 Other land transport accidents	0.286	0.714	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.286	0.714	0.000
E73 Lactose intolerance	0.284	0.715	0.001
J41 Simple and mucopurulent chronic bronchitis	0.273	0.716	0.011
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.279	0.716	0.006
X60-X84 Intentional self-harm	0.283	0.717	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.283	0.717	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.283	0.717	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.282	0.717	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.282	0.717	0.000
Q55 Other congenital malformations of male genital organs	0.282	0.717	0.000
Q52 Other congenital malformations of female genitalia	0.282	0.717	0.000
L50-L54 Urticaria and erythema	0.282	0.718	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.282	0.718	0.000
I05 Rheumatic mitral valve diseases	0.282	0.718	0.000
C82.0 Small cleaved cell, follicular	0.281	0.719	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.281	0.719	0.000
S42.9 Fracture of shoulder girdle, part unspecified	0.281	0.719	0.000
E78.8 Other disorders of lipoprotein metabolism	0.280	0.719	0.000
F84.5 Asperger's syndrome	0.281	0.719	0.000
S51 Open wound of forearm	0.281	0.719	0.000
L43.3 Subacute (active) lichen planus	0.279	0.721	0.000
L43.2 Lichenoid drug reaction	0.279	0.721	0.000
L43.1 Bullous lichen planus	0.279	0.721	0.000
L43.0 Hypertrophic lichen planus	0.279	0.721	0.000
Q82 Other congenital malformations of skin	0.279	0.721	0.000
Q51 Congenital malformations of uterus and cervix	0.278	0.722	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.277	0.722	0.001
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.277	0.722	0.001
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.277	0.722	0.001
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.277	0.722	0.001
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.277	0.722	0.001
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.277	0.722	0.001
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.277	0.722	0.001
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.277	0.722	0.001
Q53 Undescended testicle	0.278	0.722	0.000
C73 Malignant neoplasm of thyroid gland	0.277	0.723	0.000
X19 Contact with other and unspecified heat and hot substances	0.276	0.724	0.000
Y00-Y09 Assault	0.276	0.724	0.000
C85.1 B-cell lymphoma, unspecified	0.276	0.724	0.000
F81 Specific developmental disorders of scholastic skills	0.276	0.724	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.276	0.724	0.000
J32.3 Chronic sphenoidal sinusitis	0.275	0.725	0.000
J32.1 Chronic frontal sinusitis	0.275	0.725	0.000
F38 Other mood [affective] disorders	0.275	0.725	0.000
F34 Persistent mood [affective] disorders	0.275	0.725	0.000
S42.00 Fracture of clavicle (closed)	0.274	0.726	0.000
Q85 Phakomatoses, not elsewhere classified	0.274	0.726	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.274	0.726	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.274	0.726	0.000
V19 Pedal cyclist injured in other and unspecified transport accidents	0.274	0.726	0.000
S48 Traumatic amputation of shoulder and upper arm	0.273	0.726	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.273	0.726	0.000
S44 Injury of nerves at shoulder and upper arm level	0.273	0.726	0.000
S47 Crushing injury of shoulder and upper arm	0.273	0.726	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.273	0.726	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.273	0.726	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.273	0.727	0.000
L44 Other papulosquamous disorders	0.273	0.727	0.000
L41 Parapsoriasis	0.273	0.727	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.273	0.727	0.000
C44.0 Skin of lip	0.273	0.727	0.000
S56 Injury of muscle and tendon at forearm level	0.273	0.727	0.000
L10-L14 Bullous disorders	0.273	0.727	0.000
S19 Other and unspecified injuries of neck	0.273	0.727	0.000
Y59 Other and unspecified vaccines and biological substances	0.273	0.727	0.000
Y58 Bacterial vaccines	0.273	0.727	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.273	0.727	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.273	0.727	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.273	0.727	0.000
S60-S69 Injuries to the wrist and hand	0.273	0.727	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.273	0.727	0.000
V18 Pedal cyclist injured in noncollision transport accident	0.272	0.728	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.271	0.729	0.000
J31.2 Chronic pharyngitis	0.270	0.729	0.000
S27 Injury of other and unspecified intrathoracic organs	0.270	0.730	0.000
Y40.9 Systemic antibiotic, unspecified	0.270	0.730	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.269	0.731	0.000
Q54.9 Hypospadias, unspecified	0.269	0.731	0.000
T63 Toxic effect of contact with venomous animals	0.269	0.731	0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.269	0.731	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.268	0.731	0.000
Y57.7 Vitamins, not elsewhere classified	0.268	0.732	0.000
Y57.6 Other diagnostic agents	0.268	0.732	0.000
Y57.4 Pharmaceutical excipients	0.268	0.732	0.000
Y57.3 Alcohol deterrents	0.268	0.732	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.268	0.732	0.000
Y57.1 Lipotropic drugs	0.268	0.732	0.000
Y57.0 Appetite depressants [anorectics]	0.268	0.732	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.268	0.732	0.000
W07 Fall involving chair	0.267	0.733	0.000
T90.8 Sequelae of other specified injuries of head	0.267	0.733	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.266	0.733	0.000
Q25.8 Other congenital malformations of great arteries	0.266	0.733	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.266	0.733	0.000
Q25.6 Stenosis of pulmonary artery	0.266	0.733	0.000
Q25.5 Atresia of pulmonary artery	0.266	0.733	0.000
Q25.3 Stenosis of aorta	0.266	0.733	0.000
Q25.2 Atresia of aorta	0.266	0.733	0.000
Q25.0 Patent ductus arteriosus	0.266	0.733	0.000
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids	0.266	0.734	0.000
J35.2 Hypertrophy of adenoids	0.266	0.734	0.000
E61 Deficiency of other nutrient elements	0.264	0.734	0.002
F30.9 Manic episode, unspecified	0.266	0.734	0.000
F33.8 Other recurrent depressive disorders	0.266	0.734	0.000
F33.4 Recurrent depressive disorder, currently in remission	0.266	0.734	0.000
Y57.5 X-ray contrast media	0.266	0.734	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.266	0.734	0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person	0.266	0.734	0.000
T90.5 Sequelae of intracranial injury	0.265	0.735	0.000
J09-J18 Influenza and pneumonia	0.265	0.735	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.265	0.735	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.265	0.735	0.000
Q23.4 Hypoplastic left heart syndrome	0.265	0.735	0.000
Q23.3 Congenital mitral insufficiency	0.265	0.735	0.000
Q23.2 Congenital mitral stenosis	0.265	0.735	0.000
Q23.0 Congenital stenosis of aortic valve	0.265	0.735	0.000
S40.0 Contusion of shoulder and upper arm	0.264	0.736	0.000
F60.3 Emotionally unstable personality disorder	0.264	0.736	0.000
J31.1 Chronic nasopharyngitis	0.263	0.737	0.000
E78.5 Hyperlipidaemia, unspecified	0.262	0.738	0.000
T90.4 Sequelae of injury of eye and orbit	0.262	0.738	0.000
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.262	0.738	0.000
Q87.3 Congenital malformation syndromes involving early overgrowth	0.262	0.738	0.000
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.262	0.738	0.000
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.262	0.738	0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.262	0.738	0.000
S42.10 Fracture of scapula (closed)	0.262	0.738	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.261	0.739	0.000
T45.0 Antiallergic and antiemetic drugs	0.261	0.739	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.261	0.739	0.000
Y49.5 Other antipsychotics and neuroleptics	0.261	0.739	0.000
E07.8 Other specified disorders of thyroid	0.260	0.739	0.001
E07.1 Dyshormogenetic goitre	0.260	0.739	0.001
E07.0 Hypersecretion of calcitonin	0.260	0.739	0.001
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.260	0.739	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.260	0.740	0.000
E78.2 Mixed hyperlipidaemia	0.260	0.740	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.260	0.740	0.000
E21.3 Hyperparathyroidism, unspecified	0.259	0.740	0.000
S10 Superficial injury of neck	0.259	0.740	0.000
I05.1 Rheumatic mitral insufficiency	0.259	0.741	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.258	0.742	0.001
Y57.8 Other drugs and medicaments	0.258	0.742	0.000
X23 Contact with hornets, wasps and bees	0.258	0.742	0.000
Q83.1 Accessory breast	0.258	0.742	0.000
Q54.8 Other hypospadias	0.257	0.742	0.000
Q54.4 Congenital chordee	0.257	0.742	0.000
Q54.3 Hypospadias, perineal	0.257	0.742	0.000
Q54.2 Hypospadias, penoscrotal	0.257	0.742	0.000
T59.8 Other specified gases, fumes and vapours	0.257	0.743	0.000
Y48.3 Local anaesthetics	0.257	0.743	0.000
Q64 Other congenital malformations of urinary system	0.257	0.743	0.000
T78 Adverse effects, not elsewhere classified	0.256	0.744	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.256	0.744	0.000
Y52 Agents primarily affecting the cardiovascular system	0.255	0.745	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations