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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1265103
log Bayes Factor = 20.4044
Chromosome 6   position 31,100,978  (GRCh37) Explore rs1265103 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.997 0.003 0.000
E11.9 Without complications
0.996 0.004 0.000
M06.9 Rheumatoid arthritis, unspecified
0.990 0.010 0.000
M06 Other rheumatoid arthritis
0.987 0.013 0.000
E10.3 With ophthalmic complications
0.987 0.013 0.000
M05-M14 Inflammatory polyarthropathies
0.982 0.018 0.000
E14 Unspecified diabetes mellitus
0.973 0.027 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.973 0.027 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.973 0.027 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.973 0.027 0.000
Chapter XIV Diseases of the genitourinary system
0.968 0.032 0.000
# Top node
0.966 0.034 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.964 0.036 0.000
E10.1 With ketoacidosis
0.964 0.036 0.000
N40-N51 Diseases of male genital organs
0.958 0.042 0.000
N30-N39 Other diseases of urinary system
0.956 0.044 0.000
M70-M79 Other soft tissue disorders
0.955 0.045 0.000
Chapter VIII Diseases of the ear and mastoid process
0.954 0.046 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.949 0.051 0.000
N40 Hyperplasia of prostate
0.942 0.058 0.000
E14.9 Without complications
0.934 0.066 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.930 0.070 0.000
N99-N99 Other disorders of the genitourinary system
0.921 0.079 0.000
H65-H75 Diseases of middle ear and mastoid
0.905 0.095 0.000
N71 Inflammatory disease of uterus, except cervix
0.904 0.096 0.000
M79.6 Pain in limb
0.898 0.102 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.895 0.105 0.000
M75 Shoulder lesions
0.894 0.106 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.894 0.106 0.000
N35 Urethral stricture
0.893 0.107 0.000
M05 Seropositive rheumatoid arthritis
0.893 0.107 0.000
M06.3 Rheumatoid nodule
0.889 0.111 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.888 0.112 0.000
N39 Other disorders of urinary system
0.885 0.115 0.000
N36 Other disorders of urethra
0.882 0.118 0.000
E10.5 With peripheral circulatory complications
0.880 0.120 0.000
H90-H95 Other disorders of ear
0.873 0.127 0.000
K90.0 Coeliac disease
0.000 0.127 0.873
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.857 0.143 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.855 0.145 0.000
H60-H62 Diseases of external ear
0.846 0.154 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.846 0.154 0.000
E14.3 With ophthalmic complications
0.843 0.157 0.000
N71.1 Chronic inflammatory disease of uterus
0.841 0.159 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.840 0.160 0.000
M10 Gout
0.838 0.162 0.000
E16 Other disorders of pancreatic internal secretion
0.837 0.163 0.000
N35.9 Urethral stricture, unspecified
0.832 0.168 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.828 0.171 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.829 0.171 0.000
N39.4 Other specified urinary incontinence
0.829 0.171 0.000
E10.4 With neurological complications
0.825 0.175 0.000
N42 Other disorders of prostate
0.825 0.175 0.000
E10.0 With coma
0.824 0.176 0.000
N72 Inflammatory disease of cervix uteri
0.822 0.178 0.000
M79.60 Pain in limb (Multiple sites)
0.821 0.179 0.000
M79.66 Pain in limb (Lower leg)
0.819 0.181 0.000
M65-M68 Disorders of synovium and tendon
0.817 0.183 0.000
H72 Perforation of tympanic membrane
0.810 0.190 0.000
N36.8 Other specified disorders of urethra
0.800 0.200 0.000
M75.5 Bursitis of shoulder
0.800 0.200 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.800 0.200 0.000
N75 Diseases of Bartholin's gland
0.799 0.201 0.000
E16.2 Hypoglycaemia, unspecified
0.796 0.204 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.795 0.205 0.000
M06.34 Rheumatoid nodule (Hand)
0.790 0.210 0.000
N76 Other inflammation of vagina and vulva
0.787 0.213 0.000
M86-M90 Other osteopathies
0.784 0.216 0.000
E20-E35 Disorders of other endocrine glands
0.784 0.216 0.000
M79.1 Myalgia
0.784 0.216 0.000
M12 Other specific arthropathies
0.782 0.218 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.779 0.221 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.776 0.223 0.000
N71.9 Inflammatory disease of uterus, unspecified
0.774 0.226 0.000
H73 Other disorders of tympanic membrane
0.773 0.227 0.000
H90 Conductive and sensorineural hearing loss
0.772 0.228 0.000
M79.0 Rheumatism, unspecified
0.772 0.228 0.000
M65 Synovitis and tenosynovitis
0.768 0.232 0.000
E11.5 With peripheral circulatory complications
0.767 0.233 0.000
E11.1 With ketoacidosis
0.765 0.235 0.000
N49.2 Inflammatory disorders of scrotum
0.765 0.235 0.000
E10.2 With renal complications
0.762 0.238 0.000
E13 Other specified diabetes mellitus
0.762 0.238 0.000
M60-M63 Disorders of muscles
0.754 0.246 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.754 0.246 0.000
N99.1 Postprocedural urethral stricture
0.749 0.251 0.000
H61 Other disorders of external ear
0.746 0.254 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.746 0.254 0.000
E11.0 With coma
0.744 0.256 0.000
N99.8 Other postprocedural disorders of genito-urinary system
0.743 0.257 0.000
N99.3 Prolapse of vaginal vault after hysterectomy
0.743 0.257 0.000
N70 Salpingitis and oophoritis
0.742 0.258 0.000
M75.4 Impingement syndrome of shoulder
0.741 0.259 0.000
E11.3 With ophthalmic complications
0.741 0.259 0.000
E11.8 With unspecified complications
0.738 0.262 0.000
N39.9 Disorder of urinary system, unspecified
0.736 0.264 0.000
M00-M03 Infectious arthropathies
0.735 0.265 0.000
M10.9 Gout, unspecified
0.734 0.266 0.000
M80-M85 Disorders of bone density and structure
0.732 0.268 0.000
H92 Otalgia and effusion of ear
0.729 0.270 0.000
N99.0 Postprocedural renal failure
0.727 0.273 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.725 0.274 0.000
M79.63 Pain in limb (Forearm)
0.726 0.274 0.000
H74 Other disorders of middle ear and mastoid
0.724 0.276 0.000
H93 Other disorders of ear, not elsewhere classified
0.720 0.280 0.000
M79.7 Fibromyalgia
0.719 0.281 0.000
E29 Testicular dysfunction
0.718 0.281 0.000
M79.5 Residual foreign body in soft tissue
0.717 0.283 0.000
E10.8 With unspecified complications
0.717 0.283 0.000
E10.7 With multiple complications
0.717 0.283 0.000
E10.6 With other specified complications
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
N42.9 Disorder of prostate, unspecified
0.717 0.283 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.715 0.285 0.000
E11.7 With multiple complications
0.715 0.285 0.000
E11.6 With other specified complications
0.715 0.285 0.000
M75.3 Calcific tendinitis of shoulder
0.711 0.289 0.000
D70 Agranulocytosis
0.711 0.289 0.000
N36.2 Urethral caruncle
0.710 0.290 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.710 0.290 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.709 0.291 0.000
M06.8 Other specified rheumatoid arthritis
0.708 0.292 0.000
M06.2 Rheumatoid bursitis
0.708 0.292 0.000
M06.1 Adult-onset Still's disease
0.708 0.292 0.000
N42.2 Atrophy of prostate
0.707 0.293 0.000
M06.4 Inflammatory polyarthropathy
0.705 0.295 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.705 0.295 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.704 0.296 0.000
M08 Juvenile arthritis
0.704 0.296 0.000
N35.8 Other urethral stricture
0.703 0.297 0.000
M89 Other disorders of bone
0.699 0.301 0.000
E14.8 With unspecified complications
0.698 0.302 0.000
E14.7 With multiple complications
0.698 0.302 0.000
E14.6 With other specified complications
0.698 0.302 0.000
E14.5 With peripheral circulatory complications
0.698 0.302 0.000
E14.4 With neurological complications
0.698 0.302 0.000
E14.2 Withrenal complications
0.698 0.302 0.000
E14.1 With ketoacidosis
0.698 0.302 0.000
E14.0 With coma
0.698 0.302 0.000
N99.4 Postprocedural pelvic peritoneal adhesions
0.695 0.305 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.692 0.307 0.000
N32 Other disorders of bladder
0.692 0.308 0.000
D73 Diseases of spleen
0.692 0.308 0.000
M14 Arthropathies in other diseases classified elsewhere
0.689 0.310 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.687 0.313 0.000
H66 Suppurative and unspecified otitis media
0.687 0.313 0.000
N75.0 Cyst of Bartholin's gland
0.687 0.313 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.687 0.313 0.000
N46 Male infertility
0.687 0.313 0.000
N44 Torsion of testis
0.687 0.313 0.000
M79.64 Pain in limb (Hand)
0.686 0.314 0.000
M75.1 Rotator cuff syndrome
0.686 0.314 0.000
N37 Urethral disorders in diseases classified elsewhere
0.686 0.314 0.000
N33 Bladder disorders in diseases classified elsewhere
0.686 0.314 0.000
M76 Enthesopathies of lower limb, excluding foot
0.684 0.315 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.684 0.315 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.684 0.316 0.000
H72.0 Central perforation of tympanic membrane
0.684 0.316 0.000
H90.3 Sensorineural hearing loss, bilateral
0.682 0.318 0.000
N50 Other disorders of male genital organs
0.682 0.318 0.000
M79.2 Neuralgia and neuritis, unspecified
0.682 0.318 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.681 0.319 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.679 0.321 0.000
H73.8 Other specified disorders of tympanic membrane
0.678 0.322 0.000
E03 Other hypothyroidism
0.101 0.322 0.577
N34 Urethritis and urethral syndrome
0.677 0.323 0.000
M79.61 Pain in limb (Shoulder region)
0.675 0.325 0.000
H71 Cholesteatoma of middle ear
0.674 0.326 0.000
E29.1 Testicular hypofunction
0.672 0.328 0.000
M79.15 Myalgia (Pelvic region and thigh)
0.670 0.330 0.000
E50-E64 Other nutritional deficiencies
0.669 0.331 0.000
M79.9 Soft tissue disorder, unspecified
0.667 0.333 0.000
M79.3 Panniculitis, unspecified
0.667 0.333 0.000
N39.8 Other specified disorders of urinary system
0.666 0.334 0.000
M65.3 Trigger finger
0.665 0.335 0.000
M06.0 Seronegative rheumatoid arthritis
0.664 0.336 0.000
E22 Hyperfunction of pituitary gland
0.663 0.337 0.000
H60 Otitis externa
0.660 0.340 0.000
E40-E46 Malnutrition
0.656 0.344 0.000
N76.1 Subacute and chronic vaginitis
0.656 0.344 0.000
D75 Other diseases of blood and blood-forming organs
0.655 0.345 0.000
M11 Other crystal arthropathies
0.651 0.348 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.651 0.349 0.000
M40-M43 Deforming dorsopathies
0.650 0.350 0.000
H72.1 Attic perforation of tympanic membrane
0.649 0.350 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.649 0.351 0.000
H70 Mastoiditis and related conditions
0.649 0.351 0.000
H68 Eustachian salpingitis and obstruction
0.649 0.351 0.000
H67 Otitis media in diseases classified elsewhere
0.649 0.351 0.000
M84 Disorders of continuity of bone
0.649 0.351 0.000
N71.0 Acute inflammatory disease of uterus
0.648 0.352 0.000
N36.0 Urethral fistula
0.646 0.354 0.000
N00-N08 Glomerular diseases
0.645 0.355 0.000
M79.68 Pain in limb (Other)
0.644 0.356 0.000
N31.8 Other neuromuscular dysfunction of bladder
0.644 0.356 0.000
M75.8 Other shoulder lesions
0.641 0.359 0.000
E15 Nondiabetic hypoglycaemic coma
0.641 0.359 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.640 0.360 0.000
N35.1 Postinfective urethral stricture, not elsewhere classified
0.640 0.360 0.000
N35.0 Posttraumatic urethral stricture
0.640 0.360 0.000
M05.8 Other seropositive rheumatoid arthritis
0.640 0.360 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.640 0.360 0.000
M05.2 Rheumatoid vasculitis
0.640 0.360 0.000
M05.1 Rheumatoid lung disease
0.640 0.360 0.000
M05.0 Felty's syndrome
0.640 0.360 0.000
M75.9 Shoulder lesion, unspecified
0.639 0.361 0.000
Chapter XX External causes of morbidity and mortality
0.638 0.362 0.000
M12.3 Palindromic rheumatism
0.638 0.362 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.637 0.363 0.000
M06.38 Rheumatoid nodule (Other)
0.637 0.363 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.637 0.363 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.637 0.363 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.637 0.363 0.000
M06.33 Rheumatoid nodule (Forearm)
0.637 0.363 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.637 0.363 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.637 0.363 0.000
N20-N23 Urolithiasis
0.637 0.363 0.000
N99.9 Postprocedural disorder of genito-urinary system, unspecified
0.637 0.363 0.000
N99.5 Malfunction of external stoma of urinary tract
0.637 0.363 0.000
H92.1 Otorrhoea
0.636 0.364 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.635 0.365 0.000
N39.2 Orthostatic proteinuria, unspecified
0.634 0.365 0.000
N39.1 Persistent proteinuria, unspecified
0.634 0.365 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.634 0.366 0.000
N36.9 Urethral disorder, unspecified
0.632 0.367 0.000
N36.3 Prolapsed urethral mucosa
0.632 0.367 0.000
N36.1 Urethral diverticulum
0.632 0.367 0.000
M91-M94 Chondropathies
0.631 0.369 0.000
H69 Other disorders of Eustachian tube
0.631 0.369 0.000
N45 Orchitis and epididymitis
0.629 0.371 0.000
E11.2 With renal complications
0.628 0.371 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.628 0.372 0.000
D73.0 Hyposplenism
0.626 0.374 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.626 0.374 0.000
N99.2 Postprocedural adhesions of vagina
0.626 0.374 0.000
M77 Other enthesopathies
0.625 0.375 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.625 0.375 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.624 0.376 0.000
H72.8 Other perforations of tympanic membrane
0.624 0.376 0.000
H61.2 Impacted cerumen
0.622 0.378 0.000
N76.0 Acute vaginitis
0.622 0.378 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.622 0.378 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.621 0.379 0.000
M75.2 Bicipital tendinitis
0.619 0.381 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.619 0.381 0.000
M79.10 Myalgia (Multiple sites)
0.618 0.382 0.000
N32.0 Bladder-neck obstruction
0.618 0.382 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.614 0.386 0.000
N39.3 Stress incontinence
0.612 0.388 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.610 0.390 0.000
M72 Fibroblastic disorders
0.608 0.392 0.000
M79.69 Pain in limb (Site unspecified)
0.608 0.392 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.607 0.393 0.000
N49.9 Inflammatory disorder of unspecified male genital organ
0.606 0.394 0.000
N49.8 Inflammatory disorders of other specified male genital organs
0.606 0.394 0.000
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens
0.606 0.394 0.000
N49.0 Inflammatory disorders of seminal vesicle
0.606 0.394 0.000
M10.93 Gout, unspecified (Forearm)
0.606 0.394 0.000
N42.1 Congestion and haemorrhage of prostate
0.605 0.395 0.000
H61.0 Perichondritis of external ear
0.604 0.396 0.000
H90.5 Sensorineural hearing loss, unspecified
0.603 0.396 0.000
M75.0 Adhesive capsulitis of shoulder
0.603 0.397 0.000
D68 Other coagulation defects
0.603 0.397 0.000
O16 Unspecified maternal hypertension
0.602 0.398 0.000
M10.4 Other secondary gout
0.601 0.399 0.000
M10.3 Gout due to impairment of renal function
0.601 0.399 0.000
M10.2 Drug-induced gout
0.601 0.399 0.000
M10.1 Lead-induced gout
0.601 0.399 0.000
M10.0 Idiopathic gout
0.601 0.399 0.000
N76.3 Subacute and chronic vulvitis
0.601 0.399 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.600 0.400 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.600 0.400 0.000
E16.4 Abnormal secretion of gastrin
0.600 0.400 0.000
E16.3 Increased secretion of glucagon
0.600 0.400 0.000
E16.1 Other hypoglycaemia
0.600 0.400 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.600 0.400 0.000
H93.2 Other abnormal auditory perceptions
0.600 0.400 0.000
M89.8 Other specified disorders of bone
0.599 0.401 0.000
M62 Other disorders of muscle
0.598 0.402 0.000
D80-D89 Certain disorders involving the immune mechanism
0.598 0.402 0.000
M79.18 Myalgia (Other)
0.597 0.403 0.000
D55-D59 Haemolytic anaemias
0.596 0.404 0.000
N70.1 Chronic salpingitis and oophoritis
0.594 0.406 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.594 0.406 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.594 0.406 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.594 0.406 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.594 0.406 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.594 0.406 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.594 0.406 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.594 0.406 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.594 0.406 0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified
0.594 0.406 0.000
N60-N64 Disorders of breast
0.592 0.408 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.592 0.408 0.000
N42.3 Dysplasia of prostate
0.591 0.409 0.000
E13.9 Without complications
0.591 0.409 0.000
M65.34 Trigger finger-Hand
0.591 0.409 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.590 0.410 0.000
Q80-Q89 Other congenital malformations
0.586 0.414 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.586 0.414 0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.585 0.415 0.000
N50.0 Atrophy of testis
0.585 0.415 0.000
N21 Calculus of lower urinary tract
0.585 0.415 0.000
H61.1 Non-infective disorders of pinna
0.585 0.415 0.000
H65 Nonsuppurative otitis media
0.585 0.415 0.000
N75.1 Abscess of Bartholin's gland
0.582 0.418 0.000
H72.2 Other marginal perforations of tympanic membrane
0.581 0.419 0.000
Q50-Q56 Congenital malformations of genital organs
0.581 0.419 0.000
M10.99 Gout, unspecified (Site unspecified)
0.580 0.420 0.000
H80-H83 Diseases of inner ear
0.579 0.421 0.000
M89.0 Algoneurodystrophy
0.578 0.422 0.000
N76.6 Ulceration of vulva
0.577 0.423 0.000
D66 Hereditary factor VIII deficiency
0.577 0.423 0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral
0.575 0.425 0.000
M65.1 Other infective (teno)synovitis
0.574 0.426 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.573 0.427 0.000
D74 Methaemoglobinaemia
0.573 0.427 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.573 0.427 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.573 0.427 0.000
M79.79 Fibromyalgia (Site unspecified)
0.573 0.427 0.000
N75.9 Disease of Bartholin's gland, unspecified
0.573 0.427 0.000
N75.8 Other diseases of Bartholin's gland
0.573 0.427 0.000
H74.4 Polyp of middle ear
0.570 0.430 0.000
M65.8 Other synovitis and tenosynovitis
0.569 0.431 0.000
E20 Hypoparathyroidism
0.568 0.432 0.000
D68.2 Hereditary deficiency of other clotting factors
0.568 0.432 0.000
M79.00 Rheumatism, unspecified (Multiple sites)
0.567 0.432 0.000
N42.0 Calculus of prostate
0.566 0.434 0.000
E34 Other endocrine disorders
0.565 0.435 0.000
M79.54 Residual foreign body in soft tissue (Hand)
0.565 0.435 0.000
M00 Pyogenic arthritis
0.564 0.436 0.000
N76.5 Ulceration of vagina
0.564 0.436 0.000
M66 Spontaneous rupture of synovium and tendon
0.562 0.437 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.562 0.438 0.000
E32 Diseases of thymus
0.562 0.438 0.000
E31 Polyglandular dysfunction
0.562 0.438 0.000
E30 Disorders of puberty, not elsewhere classified
0.562 0.438 0.000
E26 Hyperaldosteronism
0.562 0.438 0.000
E25 Adrenogenital disorders
0.562 0.438 0.000
M79.17 Myalgia (Ankle and foot)
0.562 0.438 0.000
M79.16 Myalgia (Lower leg)
0.562 0.438 0.000
M79.14 Myalgia (Hand)
0.562 0.438 0.000
M79.13 Myalgia (Forearm)
0.562 0.438 0.000
M79.12 Myalgia (Upper arm)
0.562 0.438 0.000
M79.11 Myalgia (Shoulder region)
0.562 0.438 0.000
M71 Other bursopathies
0.561 0.439 0.000
M12.8 Other specific arthropathies, not elsewhere classified
0.560 0.439 0.000
M12.5 Traumatic arthropathy
0.560 0.439 0.000
M12.4 Intermittent hydrarthrosis
0.560 0.439 0.000
M12.2 Villonodular synovitis (pigmented)
0.560 0.439 0.000
M12.1 Kaschin-Beck disease
0.560 0.439 0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.560 0.439 0.000
M88 Paget's disease of bone [osteitis deformans]
0.559 0.441 0.000
N31.1 Reflex neuropathic bladder, not elsewhere classified
0.558 0.441 0.000
N31.0 Uninhibited neuropathic bladder, not elsewhere classified
0.558 0.441 0.000
M90 Osteopathies in diseases classified elsewhere
0.558 0.442 0.000
Chapter XXII Codes for special purposes
0.558 0.442 0.000
M79.62 Pain in limb (Upper arm)
0.557 0.442 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.557 0.443 0.000
Q35-Q37 Cleft lip and cleft palate
0.557 0.443 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.557 0.443 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.557 0.443 0.000
N76.8 Other specified inflammation of vagina and vulva
0.556 0.444 0.000
H73.9 Disorder of tympanic membrane, unspecified
0.554 0.446 0.000
H73.1 Chronic myringitis
0.554 0.446 0.000
H73.0 Acute myringitis
0.554 0.446 0.000
D72 Other disorders of white blood cells
0.554 0.446 0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified
0.554 0.446 0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.554 0.446 0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.554 0.446 0.000
E23 Hypofunction and other disorders of pituitary gland
0.554 0.446 0.000
M79.08 Rheumatism, unspecified (Other)
0.553 0.446 0.000
M79.07 Rheumatism, unspecified (Ankle and foot)
0.553 0.446 0.000
M79.06 Rheumatism, unspecified (Lower leg)
0.553 0.446 0.000
M79.05 Rheumatism, unspecified (Pelvic region and thigh)
0.553 0.446 0.000
M79.04 Rheumatism, unspecified (Hand)
0.553 0.446 0.000
M79.03 Rheumatism, unspecified (Forearm)
0.553 0.446 0.000
M79.02 Rheumatism, unspecified (Upper arm)
0.553 0.446 0.000
M79.01 Rheumatism, unspecified (Shoulder region)
0.553 0.446 0.000
M07 Psoriatic and enteropathic arthropathies
0.551 0.448 0.001
E28 Ovarian dysfunction
0.551 0.449 0.000
M84.0 Malunion of fracture
0.551 0.449 0.000
M65.2 Calcific tendinitis
0.551 0.449 0.000
M65.0 Abscess of tendon sheath
0.551 0.449 0.000
M82 Osteoporosis in diseases classified elsewhere
0.550 0.450 0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)
0.550 0.450 0.000
E22.0 Acromegaly and pituitary gigantism
0.549 0.451 0.000
E24 Cushing's syndrome
0.548 0.452 0.000
H74.9 Disorder of middle ear and mastoid, unspecified
0.548 0.452 0.000
N21.0 Calculus in bladder
0.548 0.452 0.000
E13.8 With unspecified complications
0.546 0.454 0.000
E13.7 With multiple complications
0.546 0.454 0.000
E13.6 With other specified complications
0.546 0.454 0.000
E13.5 With peripheral circulatory complications
0.546 0.454 0.000
E13.4 With neurological complications
0.546 0.454 0.000
E13.3 With ophthalmic complications
0.546 0.454 0.000
E13.2 With renal complications
0.546 0.454 0.000
E13.1 With ketoacidosis
0.546 0.454 0.000
E13.0 With coma
0.546 0.454 0.000
H74.0 Tympanosclerosis
0.546 0.454 0.000
H74.8 Other specified disorders of middle ear and mastoid
0.546 0.454 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.544 0.456 0.000
Q00-Q07 Congenital malformations of the nervous system
0.543 0.457 0.000
M13 Other arthritis
0.543 0.457 0.000
N64 Other disorders of breast
0.542 0.458 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.541 0.459 0.000
M61 Calcification and ossification of muscle
0.541 0.459 0.000
M60 Myositis
0.541 0.459 0.000
N73 Other female pelvic inflammatory diseases
0.541 0.459 0.000
D75.8 Other specified diseases of blood and blood-forming organs
0.540 0.460 0.000
H66.3 Other chronic suppurative otitis media
0.540 0.460 0.000
D75.1 Secondary polycythaemia
0.539 0.461 0.000
E22.1 Hyperprolactinaemia
0.539 0.461 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.537 0.462 0.000
N76.2 Acute vulvitis
0.537 0.463 0.000
N43 Hydrocele and spermatocele
0.536 0.464 0.000
H61.9 Disorder of external ear, unspecified
0.535 0.465 0.000
H61.8 Other specified disorders of external ear
0.535 0.465 0.000
M12.39 Palindromic rheumatism (Site unspecified)
0.535 0.465 0.000
H93.9 Disorder of ear, unspecified
0.534 0.466 0.000
N70.0 Acute salpingitis and oophoritis
0.532 0.468 0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified
0.532 0.468 0.000
N70.9 Salpingitis and oophoritis, unspecified
0.531 0.469 0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.531 0.469 0.000
N41 Inflammatory diseases of prostate
0.530 0.469 0.000
N02 Recurrent and persistent haematuria
0.530 0.470 0.000
N32.8 Other specified disorders of bladder
0.529 0.471 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.528 0.471 0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.527 0.473 0.000
M02 Reactive arthropathies
0.527 0.473 0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.527 0.473 0.000
M10.98 Gout, unspecified (Other)
0.527 0.473 0.000
M10.95 Gout, unspecified (Pelvic region and thigh)
0.527 0.473 0.000
M10.94 Gout, unspecified (Hand)
0.527 0.473 0.000
M10.92 Gout, unspecified (Upper arm)
0.527 0.473 0.000
M10.91 Gout, unspecified (Shoulder region)
0.527 0.473 0.000
M10.90 Gout, unspecified (Multiple sites)
0.527 0.473 0.000
N34.3 Urethral syndrome, unspecified
0.526 0.474 0.000
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)
0.525 0.475 0.000
M83 Adult osteomalacia
0.525 0.475 0.000
M87 Osteonecrosis
0.523 0.477 0.000
H92.2 Otorrhagia
0.523 0.477 0.000
H90.0 Conductive hearing loss, bilateral
0.522 0.478 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.520 0.480 0.000
H74.2 Discontinuity and dislocation of ear ossicles
0.519 0.481 0.000
H74.1 Adhesive middle ear disease
0.519 0.481 0.000
H60.1 Cellulitis of external ear
0.519 0.481 0.000
H90.2 Conductive hearing loss, unspecified
0.517 0.483 0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.516 0.484 0.000
H93.8 Other specified disorders of ear
0.516 0.484 0.000
H93.3 Disorders of acoustic nerve
0.516 0.484 0.000
H93.0 Degenerative and vascular disorders of ear
0.516 0.484 0.000
M79.78 Fibromyalgia (Other)
0.516 0.484 0.000
M79.77 Fibromyalgia (Ankle and foot)
0.516 0.484 0.000
M79.76 Fibromyalgia (Lower leg)
0.516 0.484 0.000
M79.75 Fibromyalgia (Pelvic region and thigh)
0.516 0.484 0.000
M79.74 Fibromyalgia (Hand)
0.516 0.484 0.000
M79.73 Fibromyalgia (Forearm)
0.516 0.484 0.000
M79.72 Fibromyalgia (Upper arm)
0.516 0.484 0.000
M79.71 Fibromyalgia (Shoulder region)
0.516 0.484 0.000
E00-E07 Disorders of thyroid gland
0.242 0.484 0.274
H93.1 Tinnitus
0.516 0.484 0.000
E29.9 Testicular dysfunction, unspecified
0.515 0.485 0.000
E29.8 Other testicular dysfunction
0.515 0.485 0.000
E29.0 Testicular hyperfunction
0.515 0.485 0.000
M79.59 Residual foreign body in soft tissue (Site unspecified)
0.514 0.486 0.000
M79.58 Residual foreign body in soft tissue (Other)
0.514 0.486 0.000
M79.57 Residual foreign body in soft tissue (Ankle and foot)
0.514 0.486 0.000
M79.56 Residual foreign body in soft tissue (Lower leg)
0.514 0.486 0.000
M79.55 Residual foreign body in soft tissue (Pelvic region and thigh)
0.514 0.486 0.000
M79.53 Residual foreign body in soft tissue (Forearm)
0.514 0.486 0.000
M79.52 Residual foreign body in soft tissue (Upper arm)
0.514 0.486 0.000
M79.51 Residual foreign body in soft tissue (Shoulder region)
0.514 0.486 0.000
M79.50 Residual foreign body in soft tissue (Multiple sites)
0.514 0.486 0.000
E12.9 Without complications
0.514 0.486 0.000
E12.8 With unspecified complications
0.514 0.486 0.000
E12.7 With multiple complications
0.514 0.486 0.000
E12.6 With other specified complications
0.514 0.486 0.000
E12.5 With peripheral circulatory complications
0.514 0.486 0.000
E12.4 With neurological complications
0.514 0.486 0.000
E12.3 With ophthalmic complications
0.514 0.486 0.000
E12.2 With renal complications
0.514 0.486 0.000
E12.1 With ketoacidosis
0.514 0.486 0.000
E12.0 With coma
0.514 0.486 0.000
M79.46 Hypertrophy of (infrapatellar) fat pad (Lower leg)
0.513 0.487 0.000
X50-X57 Overexertion, travel and privation
0.510 0.490 0.000
M70.2 Olecranon bursitis
0.509 0.490 0.000
M79.70 Fibromyalgia (Multiple sites)
0.509 0.491 0.000
Y52 Agents primarily affecting the cardiovascular system
0.509 0.491 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.508 0.492 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.508 0.492 0.000
M80 Osteoporosis with pathological fracture
0.508 0.492 0.000
M06.19 Adult-onset Still's disease (Site unspecified)
0.508 0.492 0.000
M06.18 Adult-onset Still's disease (Other)
0.508 0.492 0.000
M06.17 Adult-onset Still's disease (Ankle and foot)
0.508 0.492 0.000
M06.16 Adult-onset Still's disease (Lower leg)
0.508 0.492 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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