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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1265762
log Bayes Factor = 210.925
Chromosome 6   position 32,321,115  (GRCh37) Explore rs1265762 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
L40 Psoriasis
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E14.9 Without complications
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.000 1.000
E14.3 With ophthalmic complications
0.000 0.000 1.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
J33 Nasal polyp
0.000 0.000 1.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.000 1.000
J33.0 Polyp of nasal cavity
0.000 0.000 1.000
M35.3 Polymyalgia rheumatica
0.000 0.001 0.999
L40.5 Arthropathic psoriasis
0.000 0.001 0.999
Chapter X Diseases of the respiratory system
0.000 0.001 0.999
J40-J47 Chronic lower respiratory diseases
0.000 0.001 0.999
J45 Asthma
0.000 0.001 0.999
H36 Retinal disorders in diseases classified elsewhere
0.000 0.002 0.998
M07 Psoriatic and enteropathic arthropathies
0.000 0.002 0.998
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.002 0.998
M07.3 Other psoriatic arthropathies
0.000 0.003 0.997
H30-H36 Disorders of choroid and retina
0.000 0.003 0.997
E10.4 With neurological complications
0.000 0.003 0.997
J33.9 Nasal polyp, unspecified
0.000 0.004 0.996
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.004 0.996
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.004 0.996
L40-L45 Papulosquamous disorders
0.000 0.005 0.995
G35-G37 Demyelinating diseases of the central nervous system
0.995 0.005 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.006 0.994
M35 Other systemic involvement of connective tissue
0.000 0.006 0.994
G37 Other demyelinating diseases of central nervous system
0.994 0.006 0.000
Chapter VII Diseases of the eye and adnexa
0.000 0.007 0.993
G37.9 Demyelinating disease of central nervous system, unspecified
0.993 0.007 0.000
M20-M25 Other joint disorders
0.000 0.007 0.993
E11.1 With ketoacidosis
0.000 0.009 0.991
E10.2 With renal complications
0.000 0.010 0.990
E83.1 Disorders of iron metabolism
0.987 0.013 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.016 0.984
M06.3 Rheumatoid nodule
0.000 0.021 0.979
E10.5 With peripheral circulatory complications
0.000 0.024 0.976
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.024 0.976
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.029 0.971
L40.0 Psoriasis vulgaris
0.000 0.029 0.971
J30-J39 Other diseases of upper respiratory tract
0.000 0.029 0.971
J43 Emphysema
0.000 0.030 0.970
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.031 0.969
E10.0 With coma
0.000 0.036 0.964
J33.8 Other polyp of sinus
0.000 0.037 0.963
D64.9 Anaemia, unspecified
0.000 0.042 0.958
M45-M49 Spondylopathies
0.000 0.043 0.957
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.045 0.955
D64 Other anaemias
0.000 0.047 0.953
D60-D64 Aplastic and other anaemias
0.000 0.048 0.952
M31 Other necrotising vasculopathies
0.000 0.054 0.946
K90 Intestinal malabsorption
0.000 0.059 0.941
M06.4 Inflammatory polyarthropathy
0.000 0.059 0.941
E11.3 With ophthalmic complications
0.000 0.061 0.939
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.067 0.933
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.067 0.933
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.070 0.930
E27 Other disorders of adrenal gland
0.000 0.072 0.928
J95-J99 Other diseases of the respiratory system
0.000 0.072 0.928
E20-E35 Disorders of other endocrine glands
0.000 0.075 0.925
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.077 0.923
E27.1 Primary adrenocortical insufficiency
0.000 0.077 0.923
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.085 0.915
Chapter XI Diseases of the digestive system
0.000 0.086 0.914
K90-K93 Other diseases of the digestive system
0.000 0.086 0.914
M45 Ankylosing spondylitis
0.000 0.088 0.912
H53-H54 Visual disturbances and blindness
0.000 0.088 0.912
E06 Thyroiditis
0.000 0.089 0.911
E10.8 With unspecified complications
0.000 0.092 0.908
K75 Other inflammatory liver diseases
0.000 0.095 0.905
M31.6 Other giant cell arteritis
0.000 0.096 0.904
K70-K77 Diseases of liver
0.000 0.096 0.904
K75.4 Autoimmune hepatitis
0.000 0.098 0.902
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.101 0.899
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.101 0.899
J86 Pyothorax
0.000 0.102 0.898
M35.1 Other overlap syndromes
0.000 0.103 0.897
J43.9 Emphysema, unspecified
0.000 0.104 0.896
E10.6 With other specified complications
0.000 0.105 0.895
J95.0 Tracheostomy malfunction
0.000 0.106 0.894
M49 Spondylopathies in diseases classified elsewhere
0.000 0.107 0.893
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.107 0.893
H54 Blindness and low vision
0.000 0.110 0.890
E83 Disorders of mineral metabolism
0.853 0.111 0.035
E11.2 With renal complications
0.000 0.116 0.884
E50-E64 Other nutritional deficiencies
0.000 0.119 0.881
K75.8 Other specified inflammatory liver diseases
0.000 0.120 0.880
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.122 0.878
L80 Vitiligo
0.000 0.125 0.875
L92 Granulomatous disorders of skin and subcutaneous tissue
0.000 0.130 0.870
D50-D53 Nutritional anaemias
0.000 0.133 0.867
H33 Retinal detachments and breaks
0.000 0.133 0.867
J46 Status asthmaticus
0.000 0.134 0.866
E11.8 With unspecified complications
0.000 0.142 0.858
H34 Retinal vascular occlusions
0.000 0.143 0.857
E14.6 With other specified complications
0.000 0.144 0.856
K73 Chronic hepatitis, not elsewhere classified
0.000 0.144 0.856
J43.2 Centrilobular emphysema
0.000 0.146 0.854
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.147 0.853
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.148 0.852
M34 Systemic sclerosis
0.000 0.148 0.852
G37.8 Other specified demyelinating diseases of central nervous system
0.850 0.150 0.000
L40.8 Other psoriasis
0.000 0.151 0.849
M49.5 Collapsed vertebra in diseases classified elsewhere
0.000 0.152 0.848
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.152 0.848
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.152 0.848
E14.1 With ketoacidosis
0.000 0.153 0.847
E53 Deficiency of other B group vitamins
0.000 0.153 0.847
H33.3 Retinal breaks without detachment
0.000 0.161 0.839
L40.1 Generalised pustular psoriasis
0.000 0.162 0.838
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.162 0.838
M06.34 Rheumatoid nodule (Hand)
0.000 0.164 0.836
H35 Other retinal disorders
0.000 0.165 0.835
L10-L14 Bullous disorders
0.000 0.166 0.834
H54.0 Blindness, both eyes
0.000 0.167 0.833
E53.8 Deficiency of other specified B group vitamins
0.000 0.169 0.831
M12 Other specific arthropathies
0.000 0.171 0.829
M65-M68 Disorders of synovium and tendon
0.000 0.174 0.826
D50 Iron deficiency anaemia
0.000 0.175 0.825
H33.4 Traction detachment of retina
0.000 0.175 0.825
J86.0 Pyothorax with fistula
0.000 0.177 0.823
E14.8 With unspecified complications
0.000 0.179 0.821
E06.3 Autoimmune thyroiditis
0.000 0.181 0.819
E16.1 Other hypoglycaemia
0.000 0.182 0.818
D50.9 Iron deficiency anaemia, unspecified
0.000 0.183 0.817
H54.7 Unspecified visual loss
0.000 0.183 0.817
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.184 0.816
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.187 0.813
J86.9 Pyothorax without fistula
0.000 0.188 0.812
M80-M85 Disorders of bone density and structure
0.000 0.192 0.808
M24 Other specific joint derangements
0.000 0.193 0.807
E03.8 Other specified hypothyroidism
0.000 0.193 0.807
J39 Other diseases of upper respiratory tract
0.000 0.194 0.806
H35.4 Peripheral retinal degeneration
0.000 0.197 0.803
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.199 0.801
E14.2 Withrenal complications
0.000 0.199 0.801
J43.8 Other emphysema
0.000 0.209 0.791
M80 Osteoporosis with pathological fracture
0.000 0.213 0.787
K90.9 Intestinal malabsorption, unspecified
0.000 0.214 0.786
M49.54 Collapsed vertebra in diseases classified elsewhere (Thoracic region)
0.000 0.214 0.786
E83.3 Disorders of phosphorus metabolism
0.779 0.215 0.007
H35.8 Other specified retinal disorders
0.000 0.216 0.784
D62 Acute posthaemorrhagic anaemia
0.000 0.217 0.783
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.218 0.782
M80.9 Unspecified osteoporosis with pathological fracture
0.000 0.219 0.781
E70-E90 Metabolic disorders
0.002 0.225 0.773
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.227 0.773
L90 Atrophic disorders of skin
0.000 0.227 0.773
E83.5 Disorders of calcium metabolism
0.770 0.229 0.001
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.231 0.769
M24.1 Other articular cartilage disorders
0.000 0.232 0.768
G36 Other acute disseminated demyelination
0.762 0.238 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.241 0.759
L40.3 Pustulosis palmaris et plantaris
0.000 0.244 0.756
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.244 0.756
L92.0 Granuloma annulare
0.000 0.246 0.754
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.000 0.246 0.754
H54.2 Low vision, both eyes
0.000 0.255 0.745
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.000 0.255 0.745
J33.1 Polypoid sinus degeneration
0.000 0.257 0.743
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.258 0.742
M24.16 Other articular cartilage disorders (Lower leg)
0.000 0.259 0.741
E83.9 Disorder of mineral metabolism, unspecified
0.718 0.263 0.019
M06.0 Seronegative rheumatoid arthritis
0.000 0.263 0.737
E86 Volume depletion
0.000 0.263 0.737
J44 Other chronic obstructive pulmonary disease
0.000 0.265 0.735
M49.50 Collapsed vertebra in diseases classified elsewhere (Multiple sites in spine)
0.000 0.266 0.734
E11.5 With peripheral circulatory complications
0.000 0.267 0.733
M80.98 Unspecified osteoporosis with pathological fracture (Other)
0.000 0.268 0.732
J39.8 Other specified diseases of upper respiratory tract
0.000 0.268 0.732
M31.7 Microscopic polyangiitis
0.000 0.268 0.731
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.269 0.731
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)
0.000 0.271 0.729
L90.0 Lichen sclerosus et atrophicus
0.000 0.271 0.729
H30 Chorioretinal inflammation
0.000 0.275 0.725
M35.2 Behcet's disease
0.000 0.275 0.725
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.000 0.275 0.725
H43-H45 Disorders of vitreous body and globe
0.000 0.278 0.722
J20-J22 Other acute lower respiratory infections
0.000 0.279 0.721
M91-M94 Chondropathies
0.000 0.280 0.720
H34.9 Retinal vascular occlusion, unspecified
0.000 0.280 0.720
K82 Other diseases of gallbladder
0.000 0.282 0.718
M65 Synovitis and tenosynovitis
0.000 0.282 0.718
K71 Toxic liver disease
0.000 0.282 0.718
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.283 0.717
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M30 Polyarteritis nodosa and related conditions
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
H54.1 Blindness, one eye, low vision, other eye
0.000 0.284 0.716
L94 Other localised connective tissue disorders
0.000 0.284 0.716
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.284 0.716
M07.5 Arthropathy in ulcerative colitis
0.000 0.284 0.716
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.284 0.716
M07.2 Psoriatic spondylitis
0.000 0.284 0.716
M07.1 Arthritis mutilans
0.000 0.284 0.716
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.284 0.716
M07.38 Other psoriatic arthropathies (Other)
0.000 0.285 0.715
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.285 0.715
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.285 0.715
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.285 0.715
H35.2 Other proliferative retinopathy
0.000 0.285 0.715
L44 Other papulosquamous disorders
0.000 0.286 0.713
L41 Parapsoriasis
0.000 0.286 0.713
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.286 0.713
L40.4 Guttate psoriasis
0.000 0.287 0.713
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.287 0.713
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.287 0.713
M35.5 Multifocal fibrosclerosis
0.000 0.287 0.713
G37.5 Concentric sclerosis [Balo]
0.713 0.287 0.000
G37.4 Subacute necrotising myelitis
0.713 0.287 0.000
G37.2 Central pontine myelinolysis
0.713 0.287 0.000
G37.1 Central demyelination of corpus callosum
0.713 0.287 0.000
G37.0 Diffuse sclerosis
0.713 0.287 0.000
L12 Pemphigoid
0.000 0.290 0.710
M35.7 Hypermobility syndrome
0.000 0.291 0.709
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.291 0.709
K82.8 Other specified diseases of gallbladder
0.000 0.292 0.708
M31.3 Wegener's granulomatosis
0.000 0.293 0.707
M24.11 Other articular cartilage disorders (Shoulder region)
0.000 0.293 0.707
M34.1 CR(E)ST syndrome
0.000 0.294 0.706
M31.8 Other specified necrotising vasculopathies
0.000 0.294 0.706
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.295 0.705
E28 Ovarian dysfunction
0.000 0.297 0.703
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.298 0.702
M06.38 Rheumatoid nodule (Other)
0.000 0.298 0.702
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.298 0.702
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.298 0.702
M06.33 Rheumatoid nodule (Forearm)
0.000 0.298 0.702
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.298 0.702
M05.2 Rheumatoid vasculitis
0.000 0.301 0.699
E06.5 Other chronic thyroiditis
0.000 0.301 0.699
E11.0 With coma
0.000 0.301 0.699
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.303 0.697
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.303 0.697
J43.1 Panlobular emphysema
0.000 0.304 0.696
J43.0 MacLeod's syndrome
0.000 0.304 0.696
E27.8 Other specified disorders of adrenal gland
0.000 0.306 0.694
M06.1 Adult-onset Still's disease
0.000 0.306 0.694
K73.9 Chronic hepatitis, unspecified
0.000 0.307 0.693
E06.9 Thyroiditis, unspecified
0.000 0.309 0.691
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.309 0.691
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.690 0.310 0.000
M82 Osteoporosis in diseases classified elsewhere
0.000 0.310 0.690
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.312 0.688
M12.3 Palindromic rheumatism
0.000 0.313 0.687
E88 Other metabolic disorders
0.001 0.315 0.684
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.316 0.683
D64.4 Congenital dyserythropoietic anaemia
0.000 0.317 0.683
D64.3 Other sideroblastic anaemias
0.000 0.317 0.683
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.317 0.683
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.317 0.683
D64.0 Hereditary sideroblastic anaemia
0.000 0.317 0.683
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.317 0.683
H35.6 Retinal haemorrhage
0.000 0.318 0.682
M24.7 Protrusio acetabuli
0.000 0.318 0.682
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)
0.000 0.318 0.682
E14.5 With peripheral circulatory complications
0.000 0.319 0.681
M31.1 Thrombotic microangiopathy
0.000 0.319 0.681
L13 Other bullous disorders
0.000 0.319 0.681
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.320 0.680
M07.6 Other enteropathic arthropathies
0.000 0.320 0.680
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.321 0.679
M31.4 Aortic arch syndrome [Takayasu]
0.000 0.322 0.678
M31.2 Lethal midline granuloma
0.000 0.322 0.678
E24 Cushing's syndrome
0.000 0.322 0.678
H34.2 Other retinal artery occlusions
0.000 0.322 0.678
E07 Other disorders of thyroid
0.000 0.323 0.677
L84 Corns and callosities
0.000 0.323 0.677
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.324 0.676
K90.3 Pancreatic steatorrhoea
0.000 0.325 0.675
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.325 0.675
K90.1 Tropical sprue
0.000 0.325 0.675
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.325 0.675
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.325 0.675
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.325 0.675
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.325 0.675
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.325 0.675
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.325 0.675
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.325 0.675
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.325 0.675
M34.8 Other forms of systemic sclerosis
0.000 0.326 0.674
L92.2 Granuloma faciale [eosinophilic granuloma of skin]
0.000 0.329 0.671
M46 Other inflammatory spondylopathies
0.000 0.331 0.669
J45.1 Nonallergic asthma
0.000 0.332 0.667
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.000 0.333 0.667
H34.1 Central retinal artery occlusion
0.000 0.333 0.667
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.333 0.667
M32 Systemic lupus erythematosus
0.000 0.334 0.666
E27.5 Adrenomedullary hyperfunction
0.000 0.335 0.665
E27.0 Other adrenocortical overactivity
0.000 0.335 0.665
J96 Respiratory failure, not elsewhere classified
0.000 0.335 0.665
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.335 0.665
E14.4 With neurological complications
0.000 0.335 0.664
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.336 0.663
E32 Diseases of thymus
0.000 0.336 0.663
E31 Polyglandular dysfunction
0.000 0.336 0.663
E30 Disorders of puberty, not elsewhere classified
0.000 0.336 0.663
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.000 0.338 0.662
L87 Transepidermal elimination disorders
0.000 0.338 0.662
L86 Keratoderma in diseases classified elsewhere
0.000 0.338 0.662
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.342 0.658
E78.2 Mixed hyperlipidaemia
0.000 0.342 0.658
M06.8 Other specified rheumatoid arthritis
0.000 0.342 0.657
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.343 0.657
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.345 0.655
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.346 0.654
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.346 0.654
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.346 0.654
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.346 0.654
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.346 0.654
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.346 0.654
E40-E46 Malnutrition
0.000 0.346 0.654
E06.4 Drug-induced thyroiditis
0.000 0.347 0.653
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.347 0.653
E06.1 Subacute thyroiditis
0.000 0.347 0.653
E06.0 Acute thyroiditis
0.000 0.347 0.653
M00-M03 Infectious arthropathies
0.000 0.349 0.650
K75.2 Nonspecific reactive hepatitis
0.000 0.351 0.649
K75.1 Phlebitis of portal vein
0.000 0.351 0.649
E03.1 Congenital hypothyroidism without goitre
0.000 0.351 0.648
K77 Liver disorders in diseases classified elsewhere
0.000 0.352 0.648
J39.0 Retropharyngeal and parapharyngeal abscess
0.000 0.353 0.647
M48 Other spondylopathies
0.000 0.355 0.645
J95.5 Postprocedural subglottic stenosis
0.000 0.355 0.644
J95.4 Mendelson's syndrome
0.000 0.355 0.644
J95.3 Chronic pulmonary insufficiency following surgery
0.000 0.355 0.644
J95.2 Acute pulmonary insufficiency following nonthoracic surgery
0.000 0.355 0.644
J95.1 Acute pulmonary insufficiency following thoracic surgery
0.000 0.355 0.644
E56 Other vitamin deficiencies
0.000 0.357 0.643
D53 Other nutritional anaemias
0.000 0.357 0.643
H54.6 Unqualified visual loss, one eye
0.000 0.357 0.643
M86-M90 Other osteopathies
0.000 0.357 0.643
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.358 0.641
M49.8 Spondylopathy in other diseases classified elsewhere
0.000 0.359 0.641
M49.4 Neuropathic spondylopathy
0.000 0.359 0.641
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere
0.000 0.359 0.641
M49.2 Enterobacterial spondylitis
0.000 0.359 0.641
M49.1 Brucella spondylitis
0.000 0.359 0.641
M49.0 Tuberculosis of spine
0.000 0.359 0.641
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.360 0.640
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.360 0.640
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.361 0.639
K50-K52 Noninfective enteritis and colitis
0.019 0.361 0.620
E11.4 With neurological complications
0.000 0.361 0.639
L95 Vasculitis limited to skin, not elsewhere classified
0.000 0.361 0.639
H54.3 Unqualified visual loss, both eyes
0.000 0.362 0.638
E78.4 Other hyperlipidaemia
0.000 0.362 0.638
E83.8 Other disorders of mineral metabolism
0.612 0.363 0.025
E83.2 Disorders of zinc metabolism
0.612 0.363 0.025
E83.0 Disorders of copper metabolism
0.612 0.363 0.025
L85 Other epidermal thickening
0.000 0.363 0.637
M14 Arthropathies in other diseases classified elsewhere
0.000 0.363 0.637
H54.5 Low vision, one eye
0.000 0.365 0.635
E51 Thiamine deficiency
0.000 0.366 0.634
M94 Other disorders of cartilage
0.000 0.367 0.633
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.368 0.632
E63 Other nutritional deficiencies
0.000 0.368 0.632
E50 Vitamin A deficiency
0.000 0.368 0.632
E60 Dietary zinc deficiency
0.000 0.368 0.632
E59 Dietary selenium deficiency
0.000 0.368 0.632
E52 Niacin deficiency [pellagra]
0.000 0.368 0.632
M12.2 Villonodular synovitis (pigmented)
0.000 0.369 0.631
D51 Vitamin B12 deficiency anaemia
0.000 0.369 0.631
E25 Adrenogenital disorders
0.000 0.369 0.631
M60-M63 Disorders of muscles
0.000 0.369 0.630
K81 Cholecystitis
0.000 0.371 0.629
J99.0 Rheumatoid lung disease
0.000 0.373 0.627
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.001 0.376 0.623
L92.1 Necrobiosis lipoidica, not elsewhere classified
0.000 0.376 0.624
M34.9 Systemic sclerosis, unspecified
0.000 0.376 0.624
H20 Iridocyclitis
0.000 0.376 0.624
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.379 0.621
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.380 0.620
J41 Simple and mucopurulent chronic bronchitis
0.000 0.381 0.619
E54 Ascorbic acid deficiency
0.000 0.384 0.616
M31.9 Necrotising vasculopathy, unspecified
0.000 0.384 0.616
M34.0 Progressive systemic sclerosis
0.000 0.385 0.614
H34.0 Transient retinal artery occlusion
0.000 0.386 0.614
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.386 0.614
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.386 0.614
M46.9 Inflammatory spondylopathy, unspecified
0.000 0.388 0.612
L12.1 Cicatricial pemphigoid
0.000 0.388 0.612
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.389 0.611
J37 Chronic laryngitis and laryngotracheitis
0.000 0.391 0.609
M49.59 Collapsed vertebra in diseases classified elsewhere (Site unspecified)
0.000 0.392 0.608
M49.58 Collapsed vertebra in diseases classified elsewhere (Sacral and sacrococcygeal region)
0.000 0.392 0.608
M49.57 Collapsed vertebra in diseases classified elsewhere (Lumbosacral region)
0.000 0.392 0.608
M49.55 Collapsed vertebra in diseases classified elsewhere (Thoracolumbar region)
0.000 0.392 0.608
M49.53 Collapsed vertebra in diseases classified elsewhere (Cervicothoracic region)
0.000 0.392 0.608
M49.52 Collapsed vertebra in diseases classified elsewhere (Cervical region)
0.000 0.392 0.608
M49.51 Collapsed vertebra in diseases classified elsewhere (Occipito-atlanto-axial region)
0.000 0.392 0.608
E53.1 Pyridoxine deficiency
0.000 0.392 0.607
E53.0 Riboflavin deficiency
0.000 0.392 0.607
M15-M19 Arthrosis
0.000 0.394 0.606
M82.1 Osteoporosis in endocrine disorders
0.000 0.394 0.606
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.394 0.606
M35.8 Other specified systemic involvement of connective tissue
0.000 0.395 0.605
M24.6 Ankylosis of joint
0.000 0.395 0.605
H20.0 Acute and subacute iridocyclitis
0.000 0.396 0.604
E28.3 Primary ovarian failure
0.000 0.397 0.603
L94.2 Calcinosis cutis
0.000 0.397 0.603
K82.3 Fistula of gallbladder
0.000 0.398 0.602
E23 Hypofunction and other disorders of pituitary gland
0.000 0.398 0.602
D50.1 Sideropenic dysphagia
0.000 0.399 0.600
M12.5 Traumatic arthropathy
0.000 0.400 0.600
M48.0 Spinal stenosis
0.000 0.401 0.599
H35.1 Retinopathy of prematurity
0.000 0.401 0.598
L14 Bullous disorders in diseases classified elsewhere
0.000 0.402 0.598
M48.06 Spinal stenosis (Lumbar region)
0.000 0.402 0.598
M12.39 Palindromic rheumatism (Site unspecified)
0.000 0.402 0.598
M18 Arthrosis of first carpometacarpal joint
0.000 0.402 0.598
L85.8 Other specified epidermal thickening
0.000 0.402 0.598
J22 Unspecified acute lower respiratory infection
0.000 0.403 0.597
E89.0 Postprocedural hypothyroidism
0.000 0.405 0.595
G36.0 Neuromyelitis optica [Devic]
0.595 0.405 0.000
M12.4 Intermittent hydrarthrosis
0.000 0.406 0.594
M12.1 Kaschin-Beck disease
0.000 0.406 0.594
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.000 0.406 0.594
M24.75 Protrusio acetabuli-Pelvic/thigh
0.000 0.407 0.593
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.408 0.592
J95.9 Postprocedural respiratory disorder, unspecified
0.000 0.408 0.592
E27.9 Disorder of adrenal gland, unspecified
0.000 0.408 0.592
H10-H13 Disorders of conjunctiva
0.000 0.408 0.592
J99.8 Respiratory disorders in other diseases classified elsewhere
0.000 0.410 0.590
E70 Disorders of aromatic amino-acid metabolism
0.001 0.412 0.587
M24.0 Loose body in joint
0.000 0.413 0.587
M49.56 Collapsed vertebra in diseases classified elsewhere (Lumbar region)
0.000 0.414 0.586
M66 Spontaneous rupture of synovium and tendon
0.000 0.415 0.585
J45.8 Mixed asthma
0.000 0.415 0.585
L10 Pemphigus
0.000 0.415 0.585
M18.1 Other primary arthrosis of first carpometacarpal joint
0.000 0.415 0.585
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.417 0.583
K81.9 Cholecystitis, unspecified
0.000 0.418 0.582
H43 Disorders of vitreous body
0.000 0.419 0.581
M12.8 Other specific arthropathies, not elsewhere classified
0.000 0.419 0.581
E88.2 Lipomatosis, not elsewhere classified
0.000 0.420 0.580
M24.9 Joint derangement, unspecified
0.000 0.421 0.579
J85 Abscess of lung and mediastinum
0.000 0.422 0.578
M83 Adult osteomalacia
0.000 0.422 0.578
J39.3 Upper respiratory tract hypersensitivity reaction, site unspecified
0.000 0.422 0.578

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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