TreeWAS – Variant ID: rs12660691

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H90 Conductive and sensorineural hearing loss	0.014	0.986	0.000
H91.9 Hearing loss, unspecified	0.014	0.986	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.014	0.986	0.000
H91 Other hearing loss	0.013	0.987	0.000
H90-H95 Other disorders of ear	0.013	0.987	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.013	0.987	0.000
H90.2 Conductive hearing loss, unspecified	0.012	0.988	0.000
I51.8 Other ill-defined heart diseases	0.000	0.988	0.012
H90.5 Sensorineural hearing loss, unspecified	0.012	0.988	0.000
H90.3 Sensorineural hearing loss, bilateral	0.011	0.989	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.000	0.989	0.011
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.010	0.989	0.000
R22.2 Localised swelling, mass and lump, trunk	0.000	0.989	0.011
Z86.1 Personal history of infectious and parasitic diseases	0.000	0.990	0.010
H93 Other disorders of ear, not elsewhere classified	0.010	0.990	0.000
H90.0 Conductive hearing loss, bilateral	0.010	0.990	0.000
H91.3 Deaf mutism, not elsewhere classified	0.010	0.990	0.000
H91.2 Sudden idiopathic hearing loss	0.010	0.990	0.000
H91.1 Presbycusis	0.010	0.990	0.000
H91.0 Ototoxic hearing loss	0.010	0.990	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.010	0.990	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.010	0.990	0.000
H92 Otalgia and effusion of ear	0.009	0.990	0.000
H65-H75 Diseases of middle ear and mastoid	0.010	0.990	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.009	0.991	0.000
Chapter VIII Diseases of the ear and mastoid process	0.009	0.991	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.009	0.991	0.000
H91.8 Other specified hearing loss	0.009	0.991	0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.000	0.991	0.009
H74 Other disorders of middle ear and mastoid	0.009	0.991	0.000
R22.4 Localised swelling, mass and lump, lower limb	0.000	0.991	0.009
H71 Cholesteatoma of middle ear	0.008	0.992	0.000
H92.2 Otorrhagia	0.008	0.992	0.000
H65 Nonsuppurative otitis media	0.008	0.992	0.000
H93.8 Other specified disorders of ear	0.008	0.992	0.000
H69 Other disorders of Eustachian tube	0.008	0.992	0.000
H74.4 Polyp of middle ear	0.008	0.992	0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.992	0.008
H65.9 Nonsuppurative otitis media, unspecified	0.008	0.992	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.008	0.992	0.000
H93.9 Disorder of ear, unspecified	0.007	0.992	0.000
H93.3 Disorders of acoustic nerve	0.007	0.992	0.000
H93.2 Other abnormal auditory perceptions	0.007	0.992	0.000
H93.0 Degenerative and vascular disorders of ear	0.007	0.992	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.007	0.993	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.007	0.993	0.000
H66 Suppurative and unspecified otitis media	0.007	0.993	0.000
I51 Complications and ill-defined descriptions of heart disease	0.000	0.993	0.007
R22.0 Localised swelling, mass and lump, head	0.000	0.993	0.007
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.007	0.993	0.000
H68 Eustachian salpingitis and obstruction	0.007	0.993	0.000
H67 Otitis media in diseases classified elsewhere	0.007	0.993	0.000
N13 Obstructive and reflux uropathy	0.007	0.993	0.000
H65.4 Other chronic nonsuppurative otitis media	0.007	0.993	0.000
H74.1 Adhesive middle ear disease	0.007	0.993	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.007	0.993	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.007	0.993	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.007	0.993	0.000
H73 Other disorders of tympanic membrane	0.007	0.993	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.007	0.993	0.000
H93.1 Tinnitus	0.007	0.993	0.000
R21 Rash and other nonspecific skin eruption	0.000	0.993	0.007
R22.9 Localised swelling, mass and lump, unspecified	0.000	0.993	0.007
H70 Mastoiditis and related conditions	0.007	0.993	0.000
N13.4 Hydroureter	0.007	0.993	0.000
N13.6 Pyonephrosis	0.007	0.993	0.000
R22.7 Localised swelling, mass and lump, multiple sites	0.000	0.993	0.006
H74.9 Disorder of middle ear and mastoid, unspecified	0.006	0.993	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.007	0.993	0.000
H92.1 Otorrhoea	0.006	0.993	0.000
H69.9 Eustachian tube disorder, unspecified	0.006	0.994	0.000
H95.1 Other disorders following mastoidectomy	0.006	0.994	0.000
H69.8 Other specified disorders of Eustachian tube	0.006	0.994	0.000
H74.0 Tympanosclerosis	0.006	0.994	0.000
H72 Perforation of tympanic membrane	0.006	0.994	0.000
I51.0 Cardiac septal defect, acquired	0.000	0.994	0.006
H66.9 Otitis media, unspecified	0.006	0.994	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.006	0.994	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.006	0.994	0.000
N13.8 Other obstructive and reflux uropathy	0.006	0.994	0.000
R22.1 Localised swelling, mass and lump, neck	0.000	0.994	0.006
H65.1 Other acute nonsuppurative otitis media	0.006	0.994	0.000
H65.0 Acute serous otitis media	0.006	0.994	0.000
H69.0 Patulous Eustachian tube	0.006	0.994	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.006	0.994	0.000
I51.9 Heart disease, unspecified	0.000	0.994	0.006
I51.6 Cardiovascular disease, unspecified	0.000	0.994	0.006
M81.9 Osteoporosis, unspecified	0.000	0.994	0.006
H60-H62 Diseases of external ear	0.006	0.994	0.000
H92.0 Otalgia	0.006	0.994	0.000
L30.9 Dermatitis, unspecified	0.000	0.994	0.006
H74.3 Other acquired abnormalities of ear ossicles	0.005	0.994	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.006	0.994	0.000
H65.2 Chronic serous otitis media	0.005	0.994	0.000
H66.4 Suppurative otitis media, unspecified	0.005	0.994	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.005	0.994	0.000
H66.0 Acute suppurative otitis media	0.005	0.994	0.000
M81.98 Osteoporosis, unspecified (Other)	0.000	0.995	0.005
I51.5 Myocardial degeneration	0.000	0.995	0.005
I51.4 Myocarditis, unspecified	0.000	0.995	0.005
I51.2 Rupture of papillary muscle, not elsewhere classified	0.000	0.995	0.005
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.000	0.995	0.005
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.000	0.995	0.005
H67.8 Otitis media in other diseases classified elsewhere	0.005	0.995	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.005	0.995	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.005	0.995	0.000
H68.1 Obstruction of Eustachian tube	0.005	0.995	0.000
H68.0 Eustachian salpingitis	0.005	0.995	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.005	0.995	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.005	0.995	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.005	0.995	0.000
H80-H83 Diseases of inner ear	0.005	0.995	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.000	0.995	0.005
H54.7 Unspecified visual loss	0.005	0.995	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.005	0.995	0.000
H73.1 Chronic myringitis	0.005	0.995	0.000
H73.0 Acute myringitis	0.005	0.995	0.000
I44.7 Left bundle-branch block, unspecified	0.000	0.995	0.005
H70.8 Other mastoiditis and related conditions	0.005	0.995	0.000
H70.2 Petrositis	0.005	0.995	0.000
H70.1 Chronic mastoiditis	0.005	0.995	0.000
H70.0 Acute mastoiditis	0.005	0.995	0.000
R22.3 Localised swelling, mass and lump, upper limb	0.000	0.995	0.005
H73.8 Other specified disorders of tympanic membrane	0.005	0.995	0.000
H60 Otitis externa	0.005	0.995	0.000
H72.2 Other marginal perforations of tympanic membrane	0.005	0.995	0.000
H72.1 Attic perforation of tympanic membrane	0.005	0.995	0.000
C18.2 Ascending colon	0.000	0.995	0.005
H72.9 Perforation of tympanic membrane, unspecified	0.005	0.995	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.005	0.995	0.000
H70.9 Mastoiditis, unspecified	0.004	0.995	0.000
N13.3 Other and unspecified hydronephrosis	0.005	0.995	0.000
M35.0 Sicca syndrome [Sjogren]	0.005	0.995	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.995	0.005
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.000	0.996	0.004
M81.96 Osteoporosis, unspecified (Lower leg)	0.000	0.996	0.004
M81.94 Osteoporosis, unspecified (Hand)	0.000	0.996	0.004
M81.93 Osteoporosis, unspecified (Forearm)	0.000	0.996	0.004
M81.92 Osteoporosis, unspecified (Upper arm)	0.000	0.996	0.004
M81.91 Osteoporosis, unspecified (Shoulder region)	0.000	0.996	0.004
H62 Disorders of external ear in diseases classified elsewhere	0.004	0.996	0.000
H72.0 Central perforation of tympanic membrane	0.004	0.996	0.000
H72.8 Other perforations of tympanic membrane	0.004	0.996	0.000
H60.1 Cellulitis of external ear	0.004	0.996	0.000
H81 Disorders of vestibular function	0.004	0.996	0.000
H66.3 Other chronic suppurative otitis media	0.004	0.996	0.000
I44.0 Atrioventricular block, first degree	0.000	0.996	0.004
H82 Vertiginous syndromes in diseases classified elsewhere	0.004	0.996	0.000
W29.9 Unspecified place	0.000	0.996	0.004
Z03.9 Observation for suspected disease or condition, unspecified	0.000	0.996	0.004
H60.3 Other infective otitis externa	0.004	0.996	0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.000	0.996	0.004
L30 Other dermatitis	0.000	0.996	0.004
H60.8 Other otitis externa	0.004	0.996	0.000
H60.5 Acute otitis externa, non-infective	0.004	0.996	0.000
H60.4 Cholesteatoma of external ear	0.004	0.996	0.000
H60.2 Malignant otitis externa	0.004	0.996	0.000
H60.0 Abscess of external ear	0.004	0.996	0.000
M51.2 Other specified intervertebral disk displacement	0.004	0.996	0.000
I44 Atrioventricular and left bundle-branch block	0.000	0.996	0.004
H60.9 Otitis externa, unspecified	0.004	0.996	0.000
T82.4 Mechanical complication of vascular dialysis catheter	0.000	0.996	0.004
I51.7 Cardiomegaly	0.000	0.996	0.004
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.000	0.996	0.004
L82 Seborrhoeic keratosis	0.004	0.996	0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.000	0.996	0.004
S02.60 Fracture of mandible (closed)	0.003	0.996	0.000
H81.3 Other peripheral vertigo	0.003	0.996	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.000	0.996	0.003
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.000	0.996	0.003
L30.8 Other specified dermatitis	0.000	0.997	0.003
O75.7 Vaginal delivery following previous Caesarean section	0.003	0.997	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.003	0.997	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.003	0.997	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
H62.2 Otitis externa in mycoses	0.003	0.997	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.003	0.997	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.003	0.997	0.000
H81.1 Benign paroxysmal vertigo	0.003	0.997	0.000
C18 Malignant neoplasm of colon	0.000	0.997	0.003
T82.0 Mechanical complication of heart valve prosthesis	0.000	0.997	0.003
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.000	0.997	0.003
J32.0 Chronic maxillary sinusitis	0.003	0.997	0.000
C18.1 Appendix	0.000	0.997	0.003
H81.0 Meniere's disease	0.003	0.997	0.000
T82.1 Mechanical complication of cardiac electronic device	0.000	0.997	0.003
H81.8 Other disorders of vestibular function	0.003	0.997	0.000
H81.4 Vertigo of central origin	0.003	0.997	0.000
H83 Other diseases of inner ear	0.003	0.997	0.000
H81.9 Disorder of vestibular function, unspecified	0.003	0.997	0.000
H80 Otosclerosis	0.003	0.997	0.000
C18.4 Transverse colon	0.000	0.997	0.003
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.000	0.997	0.003
C18.5 Splenic flexure	0.000	0.997	0.003
H81.2 Vestibular neuronitis	0.003	0.997	0.000
F10.2 Dependence syndrome	0.000	0.997	0.003
H65.3 Chronic mucoid otitis media	0.003	0.997	0.000
L30.5 Pityriasis alba	0.000	0.997	0.003
L30.4 Erythema intertrigo	0.000	0.997	0.003
L30.3 Infective dermatitis	0.000	0.997	0.003
L30.2 Cutaneous autosensitisation	0.000	0.997	0.003
L30.1 Dyshidrosis [pompholyx]	0.000	0.997	0.003
L30.0 Nummular dermatitis	0.000	0.997	0.003
I44.3 Other and unspecified atrioventricular block	0.000	0.997	0.003
I44.5 Left posterior fascicular block	0.000	0.997	0.003
I44.4 Left anterior fascicular block	0.000	0.997	0.003
R49.0 Dysphonia	0.000	0.997	0.003
S02.6 Fracture of mandible	0.003	0.997	0.000
H83.8 Other specified diseases of inner ear	0.003	0.997	0.000
T82.3 Mechanical complication of other vascular grafts	0.000	0.997	0.003
I44.6 Other and unspecified fascicular block	0.000	0.997	0.003
H54 Blindness and low vision	0.003	0.997	0.000
A04.7 Enterocolitis due to Clostridium difficile	0.000	0.997	0.003
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.000	0.997	0.003
Q21.1 Atrial septal defect	0.000	0.997	0.003
S09.8 Other specified injuries of head	0.003	0.997	0.000
C18.0 Caecum	0.000	0.997	0.003
L28.0 Lichen simplex chronicus	0.000	0.997	0.003
H54.4 Blindness, one eye	0.003	0.997	0.000
I44.2 Atrioventricular block, complete	0.000	0.997	0.003
R23 Other skin changes	0.000	0.997	0.003
G47.9 Sleep disorder, unspecified	0.003	0.997	0.000
H83.9 Disease of inner ear, unspecified	0.002	0.997	0.000
H83.3 Noise effects on inner ear	0.002	0.997	0.000
H83.2 Labyrinthine dysfunction	0.002	0.997	0.000
H83.1 Labyrinthine fistula	0.002	0.997	0.000
S09 Other and unspecified injuries of head	0.003	0.997	0.000
C18.6 Descending colon	0.000	0.997	0.003
H80.8 Other otosclerosis	0.002	0.997	0.000
H80.2 Cochlear otosclerosis	0.002	0.997	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.002	0.997	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.002	0.997	0.000
E80.4 Gilbert's syndrome	0.003	0.997	0.000
C18.3 Hepatic flexure	0.000	0.997	0.003
M81 Osteoporosis without pathological fracture	0.000	0.997	0.003
C18.9 Colon, unspecified	0.000	0.997	0.003
O20 Haemorrhage in early pregnancy	0.003	0.997	0.000
O21 Excessive vomiting in pregnancy	0.003	0.997	0.000
S02 Fracture of skull and facial bones	0.003	0.997	0.000
S09.0 Injury of blood vessels of head, not elsewhere classified	0.002	0.997	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.002	0.997	0.000
O21.2 Late vomiting of pregnancy	0.002	0.997	0.000
O20.0 Threatened abortion	0.002	0.998	0.000
H61 Other disorders of external ear	0.002	0.998	0.000
S09.9 Unspecified injury of head	0.002	0.998	0.000
S02.3 Fracture of orbital floor	0.002	0.998	0.000
M51 Other intervertebral disk disorders	0.002	0.998	0.000
S02.61 Fracture of mandible (open)	0.002	0.998	0.000
R23.3 Spontaneous ecchymoses	0.000	0.998	0.002
C18.8 Overlapping lesion of colon	0.000	0.998	0.002
S02.30 Fracture of orbital floor (closed)	0.002	0.998	0.000
I73.8 Other specified peripheral vascular diseases	0.002	0.998	0.000
H61.9 Disorder of external ear, unspecified	0.002	0.998	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.002	0.998	0.000
S06.00 Concussion (without open intracranial wound)	0.002	0.998	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.002	0.998	0.000
K42.0 Umbilical hernia with obstruction, without gangrene	0.000	0.998	0.002
M51.9 Intervertebral disk disorder, unspecified	0.002	0.998	0.000
S02.4 Fracture of malar and maxillary bones	0.002	0.998	0.000
R20 Disturbances of skin sensation	0.000	0.998	0.002
T85 Complications of other internal prosthetic devices, implants and grafts	0.000	0.998	0.002
M54.22 Cervicalgia (Cervical region)	0.000	0.998	0.002
O21.0 Mild hyperemesis gravidarum	0.002	0.998	0.000
I34.0 Mitral (valve) insufficiency	0.000	0.998	0.002
M51.4 Schmorl's nodes	0.002	0.998	0.000
T78.3 Angioneurotic oedema	0.000	0.998	0.002
S06.2 Diffuse brain injury	0.002	0.998	0.000
S06.0 Concussion	0.002	0.998	0.000
H54.6 Unqualified visual loss, one eye	0.002	0.998	0.000
H54.5 Low vision, one eye	0.002	0.998	0.000
H54.3 Unqualified visual loss, both eyes	0.002	0.998	0.000
H54.2 Low vision, both eyes	0.002	0.998	0.000
H54.1 Blindness, one eye, low vision, other eye	0.002	0.998	0.000
S06 Intracranial injury	0.002	0.998	0.000
W29 Contact with other powered hand tools and household machinery	0.000	0.998	0.002
K83.1 Obstruction of bile duct	0.000	0.998	0.002
S02.9 Fracture of skull and facial bones, part unspecified	0.002	0.998	0.000
I34 Nonrheumatic mitral valve disorders	0.000	0.998	0.002
S02.40 Fracture of malar and maxillary bones (closed)	0.002	0.998	0.000
S02.5 Fracture of tooth	0.002	0.998	0.000
O20.8 Other haemorrhage in early pregnancy	0.002	0.998	0.000
R49.8 Other and unspecified voice disturbances	0.000	0.998	0.002
R74.8 Abnormal levels of other serum enzymes	0.002	0.998	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.002	0.998	0.000
S09.7 Multiple injuries of head	0.002	0.998	0.000
S09.2 Traumatic rupture of ear drum	0.002	0.998	0.000
S09.1 Injury of muscle and tendon of head	0.002	0.998	0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.000	0.998	0.002
O20-O29 Other maternal disorders predominantly related to pregnancy	0.002	0.998	0.000
N15.9 Renal tubulo-interstitial disease, unspecified	0.002	0.998	0.000
R49 Voice disturbances	0.000	0.998	0.002
C18.7 Sigmoid colon	0.000	0.998	0.002
C71.1 Frontal lobe	0.002	0.998	0.000
M81.8 Other osteoporosis	0.000	0.998	0.002
M81.6 Localised osteoporosis [Lequesne]	0.000	0.998	0.002
M81.5 Idiopathic osteoporosis	0.000	0.998	0.002
M81.3 Postsurgical malabsorption osteoporosis	0.000	0.998	0.002
M81.1 Postoophorectomy osteoporosis	0.000	0.998	0.002
M81.0 Postmenopausal osteoporosis	0.000	0.998	0.002
S02.8 Fractures of other skull and facial bones	0.002	0.998	0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.000	0.998	0.002
R23.1 Pallor	0.000	0.998	0.002
H54.9 Unspecified visual impairment (binocular)	0.002	0.998	0.000
O21.8 Other vomiting complicating pregnancy	0.002	0.998	0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.000	0.998	0.002
O21.9 Vomiting of pregnancy, unspecified	0.002	0.998	0.000
S02.7 Multiple fractures involving skull and facial bones	0.002	0.998	0.000
I30-I52 Other forms of heart disease	0.000	0.998	0.002
R23.0 Cyanosis	0.000	0.998	0.002
S06.3 Focal brain injury	0.002	0.998	0.000
K05.3 Chronic periodontitis	0.000	0.998	0.002
K74.6 Other and unspecified cirrhosis of liver	0.002	0.998	0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.000	0.998	0.002
N15 Other renal tubulo-interstitial diseases	0.002	0.998	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.002	0.998	0.000
S06.5 Traumatic subdural haemorrhage	0.002	0.998	0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.000	0.998	0.002
S02.50 Fracture of tooth (closed)	0.002	0.998	0.000
I74.5 Embolism and thrombosis of iliac artery	0.002	0.998	0.000
M81.2 Osteoporosis of disuse	0.000	0.998	0.002
Z02.8 Other examinations for administrative purposes	0.002	0.998	0.000
L28 Lichen simplex chronicus and prurigo	0.000	0.998	0.002
S02.31 Fracture of orbital floor (open)	0.002	0.998	0.000
H53.4 Visual field defects	0.000	0.998	0.002
K74.3 Primary biliary cirrhosis	0.002	0.998	0.000
M51.3 Other specified intervertebral disk degeneration	0.002	0.998	0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.002	0.998	0.000
R23.2 Flushing	0.000	0.998	0.002
Z03.3 Observation for suspected nervous system disorder	0.000	0.998	0.002
O26 Maternal care for other conditions predominantly related to pregnancy	0.002	0.998	0.000
H61.3 Acquired stenosis of external ear canal	0.002	0.998	0.000
I34.1 Mitral (valve) prolapse	0.000	0.998	0.002
I37 Pulmonary valve disorders	0.000	0.998	0.002
N10-N16 Renal tubulo-interstitial diseases	0.002	0.998	0.000
I24.8 Other forms of acute ischaemic heart disease	0.000	0.998	0.002
I37.1 Pulmonary valve insufficiency	0.000	0.998	0.002
T85.4 Mechanical complication of breast prosthesis and implant	0.000	0.998	0.002
S06.30 Focal brain injury (without open intracranial wound)	0.002	0.998	0.000
R20.3 Hyperaesthesia	0.000	0.998	0.002
R20.1 Hypoaesthesia of skin	0.000	0.998	0.002
Z93.3 Colostomy status	0.002	0.998	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.002	0.998	0.000
I73.0 Raynaud's syndrome	0.002	0.998	0.000
I36 Nonrheumatic tricuspid valve disorders	0.000	0.998	0.002
M81.4 Drug-induced osteoporosis	0.000	0.998	0.002
S00-S09 Injuries to the head	0.002	0.998	0.000
S06.01 Concussion (with open intracranial wound)	0.002	0.998	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.002	0.998	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.002	0.998	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.000	0.998	0.002
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.002	0.998	0.000
O26.8 Other specified pregnancy-related conditions	0.002	0.998	0.000
S02.0 Fracture of vault of skull	0.002	0.998	0.000
W29.8 Other specified place	0.000	0.998	0.002
W29.6 Industrial and construction area	0.000	0.998	0.002
W29.0 Home	0.000	0.998	0.002
W29.7 Farm	0.000	0.998	0.002
W29.5 Trade and service area	0.000	0.998	0.002
W29.4 Street and highway	0.000	0.998	0.002
W29.3 Sports and athletics area	0.000	0.998	0.002
W29.2 School, other institution and public administrative area	0.000	0.998	0.002
W29.1 Residential institution	0.000	0.998	0.002
O24 Diabetes mellitus in pregnancy	0.002	0.998	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.002	0.998	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.000	0.998	0.002
I34.8 Other nonrheumatic mitral valve disorders	0.000	0.998	0.002
S06.7 Intracranial injury with prolonged coma	0.002	0.998	0.000
S06.1 Traumatic cerebral oedema	0.002	0.998	0.000
I73 Other peripheral vascular diseases	0.002	0.998	0.000
S02.51 Fracture of tooth (open)	0.002	0.998	0.000
C26.0 Intestinal tract, part unspecified	0.000	0.998	0.002
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.000	0.998	0.002
N82.3 Fistula of vagina to large intestine	0.002	0.998	0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.000	0.998	0.002
Y83.4 Other reconstructive surgery	0.000	0.998	0.002
I34.2 Nonrheumatic mitral (valve) stenosis	0.000	0.998	0.002
K05.6 Periodontal disease, unspecified	0.000	0.998	0.002
S06.8 Other intracranial injuries	0.002	0.998	0.000
O28 Abnormal findings on antenatal screening of mother	0.002	0.998	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.998	0.002
S02.80 Fractures of other skull and facial bones (closed)	0.002	0.998	0.000
R49.2 Hypernasality and hyponasality	0.000	0.998	0.002
R49.1 Aphonia	0.000	0.998	0.002
S06.9 Intracranial injury, unspecified	0.002	0.998	0.000
I49 Other cardiac arrhythmias	0.000	0.998	0.002
N11 Chronic tubulo-interstitial nephritis	0.002	0.998	0.000
O29 Complications of anaesthesia during pregnancy	0.002	0.998	0.000
O22 Venous complications in pregnancy	0.002	0.998	0.000
O25 Malnutrition in pregnancy	0.002	0.998	0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.000	0.998	0.002
M81.08 Postmenopausal osteoporosis (Other)	0.000	0.998	0.002
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.000	0.998	0.002
M81.06 Postmenopausal osteoporosis (Lower leg)	0.000	0.998	0.002
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.000	0.998	0.002
M81.04 Postmenopausal osteoporosis (Hand)	0.000	0.998	0.002
M81.03 Postmenopausal osteoporosis (Forearm)	0.000	0.998	0.002
M81.02 Postmenopausal osteoporosis (Upper arm)	0.000	0.998	0.002
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.000	0.998	0.002
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.000	0.998	0.002
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.000	0.998	0.002
M81.18 Postoophorectomy osteoporosis (Other)	0.000	0.998	0.002
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.000	0.998	0.002
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.000	0.998	0.002
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.000	0.998	0.002
M81.14 Postoophorectomy osteoporosis (Hand)	0.000	0.998	0.002
M81.13 Postoophorectomy osteoporosis (Forearm)	0.000	0.998	0.002
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.000	0.998	0.002
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.000	0.998	0.002
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.000	0.998	0.002
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.000	0.998	0.002
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.000	0.998	0.002
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.000	0.998	0.002
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.000	0.998	0.002
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.000	0.998	0.002
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.000	0.998	0.002
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.000	0.998	0.002
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.000	0.998	0.002
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.000	0.998	0.002
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.000	0.998	0.002
M81.59 Idiopathic osteoporosis (Site unspecified)	0.000	0.998	0.002
M81.58 Idiopathic osteoporosis (Other)	0.000	0.998	0.002
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.000	0.998	0.002
M81.56 Idiopathic osteoporosis (Lower leg)	0.000	0.998	0.002
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.000	0.998	0.002
M81.54 Idiopathic osteoporosis (Hand)	0.000	0.998	0.002
M81.53 Idiopathic osteoporosis (Forearm)	0.000	0.998	0.002
M81.52 Idiopathic osteoporosis (Upper arm)	0.000	0.998	0.002
M81.51 Idiopathic osteoporosis (Shoulder region)	0.000	0.998	0.002
M81.50 Idiopathic osteoporosis (Multiple sites)	0.000	0.998	0.002
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.000	0.998	0.002
M81.68 Localized osteoporosis [Lequesne] (Other)	0.000	0.998	0.002
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.000	0.998	0.002
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.000	0.998	0.002
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.000	0.998	0.002
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.000	0.998	0.002
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.000	0.998	0.002
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.000	0.998	0.002
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.000	0.998	0.002
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.000	0.998	0.002
M81.89 Other osteoporosis (Site unspecified)	0.000	0.998	0.002
M81.88 Other osteoporosis (Other)	0.000	0.998	0.002
M81.87 Other osteoporosis (Ankle and foot)	0.000	0.998	0.002
M81.86 Other osteoporosis (Lower leg)	0.000	0.998	0.002
M81.85 Other osteoporosis (Pelvic region and thigh)	0.000	0.998	0.002
M81.84 Other osteoporosis (Hand)	0.000	0.998	0.002
M81.83 Other osteoporosis (Forearm)	0.000	0.998	0.002
M81.82 Other osteoporosis (Upper arm)	0.000	0.998	0.002
M81.81 Other osteoporosis (Shoulder region)	0.000	0.998	0.002
M81.80 Other osteoporosis (Multiple sites)	0.000	0.998	0.002
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.998	0.002
R23.8 Other and unspecified skin changes	0.000	0.998	0.002
S02.81 Fractures of other skull and facial bones (open)	0.002	0.998	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.998	0.002
N85.2 Hypertrophy of uterus	0.002	0.998	0.000
H54.0 Blindness, both eyes	0.002	0.998	0.000
H80.9 Otosclerosis, unspecified	0.001	0.998	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.002	0.998	0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.002	0.998	0.000
S02.71 Multiple fractures involving skull and facial bones (open)	0.002	0.998	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.002	0.998	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.002	0.998	0.000
O24.9 Diabetes mellitus in pregnancy, unspecified	0.002	0.998	0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.002	0.998	0.000
I52 Other heart disorders in diseases classified elsewhere	0.000	0.998	0.002
I48 Atrial fibrillation and flutter	0.000	0.998	0.002
I43 Cardiomyopathy in diseases classified elsewhere	0.000	0.998	0.002
I41 Myocarditis in diseases classified elsewhere	0.000	0.998	0.002
I40 Acute myocarditis	0.000	0.998	0.002
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.000	0.998	0.002
I33 Acute and subacute endocarditis	0.000	0.998	0.002
I32 Pericarditis in diseases classified elsewhere	0.000	0.998	0.002
M07.39 Other psoriatic arthropathies (Site unspecified)	0.000	0.998	0.002
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.002	0.998	0.000
I49.3 Ventricular premature depolarisation	0.000	0.998	0.002
N15.8 Other specified renal tubulo-interstitial diseases	0.002	0.998	0.000
N15.1 Renal and perinephric abscess	0.002	0.998	0.000
N15.0 Balkan nephropathy	0.002	0.998	0.000
R79.9 Abnormal finding of blood chemistry, unspecified	0.002	0.998	0.000
S06.4 Epidural haemorrhage	0.002	0.998	0.000
M81.29 Osteoporosis of disuse (Site unspecified)	0.000	0.998	0.001
M81.28 Osteoporosis of disuse (Other)	0.000	0.998	0.001
M81.27 Osteoporosis of disuse (Ankle and foot)	0.000	0.998	0.001
M81.26 Osteoporosis of disuse (Lower leg)	0.000	0.998	0.001
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.000	0.998	0.001
M81.24 Osteoporosis of disuse (Hand)	0.000	0.998	0.001
M81.23 Osteoporosis of disuse (Forearm)	0.000	0.998	0.001
M81.22 Osteoporosis of disuse (Upper arm)	0.000	0.998	0.001
M81.21 Osteoporosis of disuse (Shoulder region)	0.000	0.998	0.001
G56.2 Lesion of ulnar nerve	0.000	0.998	0.002
I44.1 Atrioventricular block, second degree	0.000	0.998	0.002
K57.1 Diverticular disease of small intestine without perforation or abscess	0.000	0.998	0.002
K74.5 Biliary cirrhosis, unspecified	0.002	0.998	0.000
S02.1 Fracture of base of skull	0.002	0.998	0.000
M51.19 Lumbar and other intervertebral disc disorders with radiculopathy; site unspecified	0.001	0.998	0.000
M51.16 Intervertebral disc disorders w radiculopathy, lumbar region	0.001	0.998	0.000
M51.37 Other intervertebral disc degeneration, lumbosacral region	0.001	0.998	0.000
H61.1 Non-infective disorders of pinna	0.001	0.998	0.001
I37.9 Pulmonary valve disorder, unspecified	0.000	0.998	0.002
I37.8 Other pulmonary valve disorders	0.000	0.998	0.002
I37.2 Pulmonary valve stenosis with insufficiency	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations