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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12661290
log Bayes Factor = 7.99556
Chromosome 6   position 462,341  (GRCh37) Explore rs12661290 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
C44 Other malignant neoplasms of skin
0.000 0.000 1.000
C44.7 Skin of lower limb, including hip
0.000 0.000 1.000
C44.3 Skin of other and unspecified parts of face
0.000 0.001 0.999
C44.5 Skin of trunk
0.000 0.002 0.998
C44.4 Skin of scalp and neck
0.000 0.002 0.998
C44.6 Skin of upper limb, including shoulder
0.000 0.005 0.995
C44.0 Skin of lip
0.000 0.167 0.833
C44.9 Malignant neoplasm of skin, unspecified
0.000 0.232 0.768
C44.8 Overlapping lesion of skin
0.000 0.283 0.717
C44.2 Skin of ear and external auricular canal
0.000 0.351 0.649
C44.1 Skin of eyelid, including canthus
0.000 0.370 0.630
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.701 0.299
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.780 0.220
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.784 0.216
C85.1 B-cell lymphoma, unspecified
0.000 0.785 0.215
C91 Lymphoid leukaemia
0.000 0.790 0.210
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.793 0.207
C91.1 Chronic lymphocytic leukaemia
0.000 0.796 0.204
C90 Multiple myeloma and malignant plasma cell neoplasms
0.000 0.805 0.195
C88 Malignant immunoproliferative diseases
0.000 0.806 0.194
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.813 0.187
C92 Myeloid leukaemia
0.000 0.815 0.185
C90.0 Multiple myeloma
0.000 0.818 0.182
C88.0 Waldenstrom's macroglobulinaemia
0.000 0.819 0.181
C91.4 Hairy-cell leukaemia
0.000 0.828 0.172
C85.7 Other specified types of non-Hodgkin's lymphoma
0.000 0.828 0.172
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.000 0.835 0.165
C95 Leukaemia of unspecified cell type
0.000 0.835 0.165
C86 Other specified types of T/NK-cell lymphoma
0.000 0.839 0.161
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.842 0.158
C85.0 Lymphosarcoma
0.000 0.842 0.158
C92.1 Chronic myeloid leukaemia
0.000 0.843 0.157
C91.0 Acute lymphoblastic leukaemia
0.000 0.843 0.157
C93 Monocytic leukaemia
0.000 0.843 0.157
C83.3 Large cell (diffuse)
0.000 0.845 0.155
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.845 0.155
C94 Other leukaemias of specified cell type
0.000 0.845 0.155
C91.8 Mature B-cell leukaemia Burkitt-type
0.000 0.850 0.150
C91.7 Other lymphoid leukaemia
0.000 0.850 0.150
C91.6 Prolymphocytic leukaemia of T-cell type
0.000 0.850 0.150
C91.3 Prolymphocytic leukaemia
0.000 0.850 0.150
C91.2 Subacute lymphocytic leukaemia
0.000 0.850 0.150
C90.1 Plasma cell leukaemia
0.000 0.850 0.150
C43 Malignant melanoma of skin
0.000 0.856 0.144
C92.7 Other myeloid leukaemia
0.000 0.857 0.143
C83.7 Burkitt's tumour
0.000 0.859 0.141
C90.3 Solitary plasmacytoma
0.000 0.860 0.140
C91.9 Lymphoid leukaemia, unspecified
0.000 0.860 0.140
C88.9 Malignant immunoproliferative disease, unspecified
0.000 0.860 0.139
C88.7 Other malignant immunoproliferative diseases
0.000 0.860 0.139
C88.3 Immunoproliferative small intestinal disease
0.000 0.860 0.139
C88.2 Gamma heavy chain disease
0.000 0.860 0.139
C88.1 Alpha heavy chain disease
0.000 0.860 0.139
C43.3 Malignant melanoma of other and unspecified parts of face
0.000 0.861 0.139
C92.4 Acute promyelocytic leukaemia
0.000 0.862 0.138
C92.9 Myeloid leukaemia, unspecified
0.000 0.862 0.138
C83.0 Small cell (diffuse)
0.000 0.864 0.136
C83.6 Undifferentiated (diffuse)
0.000 0.866 0.134
C83.5 Lymphoblastic (diffuse)
0.000 0.866 0.134
C83.4 Immunoblastic (diffuse)
0.000 0.866 0.134
C83.2 Mixed small and large cell (diffuse)
0.000 0.866 0.134
C91.5 Adult T-cell leukaemia
0.000 0.866 0.134
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.000 0.867 0.133
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.000 0.867 0.133
C92.5 Acute myelomonocytic leukaemia
0.000 0.867 0.133
C92.3 Myeloid sarcoma
0.000 0.867 0.133
C92.2 Subacute myeloid leukaemia
0.000 0.867 0.133
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.000 0.867 0.132
C95.9 Leukaemia, unspecified
0.000 0.872 0.128
C90.2 Plasmacytoma, extramedullary
0.000 0.877 0.123
C86.5 Angioimmunoblastic T-cell lymphoma
0.000 0.878 0.122
C92.0 Acute myeloid leukaemia
0.000 0.878 0.122
C95.7 Other leukaemia of unspecified cell type
0.000 0.882 0.118
C95.2 Subacute leukaemia of unspecified cell type
0.000 0.882 0.118
C95.1 Chronic leukaemia of unspecified cell type
0.000 0.882 0.118
C95.0 Acute leukaemia of unspecified cell type
0.000 0.882 0.118
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.000 0.884 0.116
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.000 0.884 0.116
C86.4 Blastic NK-cell lymphoma
0.000 0.884 0.116
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.000 0.884 0.116
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.000 0.884 0.116
C86.1 Hepatosplenic T-cell lymphoma
0.000 0.884 0.116
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.000 0.884 0.116
C83.1 Small cleaved cell (diffuse)
0.000 0.886 0.114
C93.1 Chronic monocytic leukaemia
0.000 0.886 0.114
C93.9 Monocytic leukaemia, unspecified
0.000 0.887 0.112
C93.7 Other monocytic leukaemia
0.000 0.887 0.112
C93.3 Juvenile myelomonocytic leukaemia
0.000 0.887 0.112
C93.2 Subacute monocytic leukaemia
0.000 0.887 0.112
C93.0 Acute monocytic leukaemia
0.000 0.887 0.112
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.888 0.112
C94.7 Other specified leukaemias
0.000 0.888 0.111
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.000 0.888 0.111
C94.5 Acute myelofibrosis
0.000 0.888 0.111
C94.4 Acute panmyelosis
0.000 0.888 0.111
C94.3 Mast cell leukaemia
0.000 0.888 0.111
C94.2 Acute megakaryoblastic leukaemia
0.000 0.888 0.111
C94.1 Chronic erythraemia
0.000 0.888 0.111
C94.0 Acute erythraemia and erythroleukaemia
0.000 0.888 0.111
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.000 0.888 0.111
C96.8 Histiocytic sarcoma
0.000 0.888 0.111
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.888 0.111
C96.6 Unifocal Langerhans-cell histiocytosis
0.000 0.888 0.111
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.000 0.888 0.111
C96.4 Sarcoma of dendritic cells (accessory cells)
0.000 0.888 0.111
C96.3 True histiocytic lymphoma
0.000 0.888 0.111
C96.2 Malignant mast cell tumour
0.000 0.888 0.111
C96.1 Malignant histiocytosis
0.000 0.888 0.111
C96.0 Letterer-Siwe disease
0.000 0.888 0.111
C43.2 Malignant melanoma of ear and external auricular canal
0.000 0.892 0.108
C43.8 Overlapping malignant melanoma of skin
0.000 0.897 0.103
C43.0 Malignant melanoma of lip
0.000 0.897 0.103
C81 Hodgkin's disease
0.000 0.905 0.095
C43.7 Malignant melanoma of lower limb, including hip
0.000 0.913 0.087
C43.1 Malignant melanoma of eyelid, including canthus
0.000 0.914 0.085
C43.9 Malignant melanoma of skin, unspecified
0.000 0.915 0.085
C43.6 Malignant melanoma of upper limb, including shoulder
0.000 0.916 0.084
C84.8 Cutaneous T-cell lymphoma, unspecified
0.000 0.917 0.083
C84.9 Mature T/NK-cell lymphoma, unspecified
0.000 0.920 0.080
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.000 0.920 0.080
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.000 0.920 0.080
C84.3 Lymphoepithelioid lymphoma
0.000 0.920 0.080
C84.2 T-zone lymphoma
0.000 0.920 0.080
C84.1 Sezary's diease
0.000 0.920 0.080
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.921 0.079
C81.2 Mixed cellularity
0.000 0.927 0.073
C84.4 Peripheral T-cell lymphoma
0.000 0.928 0.072
C84.0 Mycosis fungoides
0.000 0.929 0.071
C81.7 Other Hodgkin's disease
0.000 0.932 0.068
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.000 0.932 0.068
C81.3 Lymphocytic depletion
0.000 0.932 0.068
C81.0 Lymphocytic predominance
0.000 0.934 0.066
C43.5 Malignant melanoma of trunk
0.000 0.937 0.063
D04 Carcinoma in situ of skin
0.000 0.938 0.062
C82.1 Mixed small cleaved and large cell, follicular
0.000 0.938 0.061
C84.5 Other and unspecified T-cell lymphomas
0.000 0.939 0.060
D04.5 Skin of trunk
0.000 0.940 0.060
D04.6 Skin of upper limb, including shoulder
0.000 0.941 0.059
C82.6 Cutaneous follicle centre lymphoma
0.000 0.943 0.057
C82.5 Diffuse follicle centre lymphoma
0.000 0.943 0.057
C82.3 Follicular lymphoma grade IIIa
0.000 0.943 0.057
C82.2 Large cell, follicular
0.000 0.944 0.056
D04.3 Skin of other and unspecified parts of face
0.000 0.944 0.056
D04.7 Skin of lower limb, including hip
0.000 0.944 0.056
C82.0 Small cleaved cell, follicular
0.000 0.947 0.053
D04.4 Skin of scalp and neck
0.000 0.948 0.052
C82.4 Follicular lymphoma grade IIIb
0.000 0.951 0.048
D04.1 Skin of eyelid, including canthus
0.000 0.952 0.048
C81.1 Nodular sclerosis
0.000 0.953 0.046
D04.8 Skin of other sites
0.000 0.955 0.045
D04.0 Skin of lip
0.000 0.955 0.045
D04.9 Skin, unspecified
0.000 0.957 0.042
C43.4 Malignant melanoma of scalp and neck
0.001 0.958 0.041
D04.2 Skin of ear and external auricular canal
0.000 0.958 0.042
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.958 0.042
C81.9 Hodgkin's disease, unspecified
0.000 0.959 0.040
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.000 0.963 0.036
D00-D09 In situ neoplasms
0.000 0.969 0.031
D03 Melanoma in situ
0.000 0.972 0.028
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.000 0.974 0.026
Chapter II Neoplasms
0.000 0.975 0.025
D03.2 Melanoma in situ of ear and external auricular canal
0.000 0.976 0.024
D03.3 Melanoma in situ of other and unspecified parts of face
0.000 0.976 0.024
D02 Carcinoma in situ of middle ear and respiratory system
0.000 0.977 0.023
D03.6 Melanoma in situ of upper limb, including shoulder
0.000 0.977 0.023
D00.0 Lip, oral cavity and pharynx
0.000 0.978 0.022
D01 Carcinoma in situ of other and unspecified digestive organs
0.000 0.978 0.022
D03.7 Melanoma in situ of lower limb, including hip
0.000 0.978 0.022
D07 Carcinoma in situ of other and unspecified genital organs
0.000 0.979 0.021
D03.9 Melanoma in situ, unspecified
0.000 0.980 0.020
D03.8 Melanoma in situ of other sites
0.000 0.980 0.020
D03.1 Melanoma in situ of eyelid, including canthus
0.000 0.980 0.020
D03.0 Melanoma in situ of lip
0.000 0.980 0.020
D00.2 Stomach
0.000 0.981 0.019
D00.1 Oesophagus
0.000 0.981 0.019
C40-C41 Malignant neoplasms of bone and articular cartilage
0.000 0.982 0.018
D02.0 Larynx
0.000 0.983 0.017
D03.4 Melanoma in situ of scalp and neck
0.000 0.983 0.017
M25.46 Effusion of joint (Lower leg)
0.017 0.983 0.000
D01.3 Anus and anal canal
0.000 0.983 0.017
D02.4 Respiratory system, unspecified
0.000 0.983 0.017
D02.3 Other parts of respiratory system
0.000 0.983 0.017
D02.2 Bronchus and lung
0.000 0.983 0.017
D02.1 Trachea
0.000 0.983 0.017
D07.4 Penis
0.000 0.983 0.017
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.000 0.984 0.016
D07.5 Prostate
0.000 0.984 0.016
D09 Carcinoma in situ of other and unspecified sites
0.000 0.984 0.016
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.000 0.984 0.016
D01.9 Digestive organ, unspecified
0.000 0.984 0.016
D01.7 Other specified digestive organs
0.000 0.984 0.016
D01.5 Liver, gallbladder and bile ducts
0.000 0.984 0.016
D01.4 Other and unspecified parts of intestine
0.000 0.984 0.016
D01.1 Rectosigmoid junction
0.000 0.984 0.016
D07.2 Vagina
0.000 0.984 0.016
D07.6 Other and unspecified male genital organs
0.000 0.985 0.015
D07.3 Other and unspecified female genital organs
0.000 0.985 0.015
D07.0 Endometrium
0.000 0.985 0.015
D01.2 Rectum
0.000 0.985 0.015
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.000 0.985 0.015
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites
0.000 0.986 0.014
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.000 0.986 0.014
D01.0 Colon
0.000 0.986 0.014
D03.5 Melanoma in situ of trunk
0.000 0.986 0.013
C42 hematopoietic and reticuloendothelial systems (ICD-O-3 specific)
0.000 0.986 0.013
C69 Malignant neoplasm of eye and adnexa
0.000 0.987 0.013
C40 Malignant neoplasm of bone and articular cartilage of limbs
0.000 0.988 0.012
D06 Carcinoma in situ of cervix uteri
0.000 0.988 0.012
D09.9 Carcinoma in situ, unspecified
0.000 0.988 0.011
D09.7 Carcinoma in situ of other specified sites
0.000 0.988 0.011
D09.3 Thyroid and other endocrine glands
0.000 0.988 0.011
D09.2 Eye
0.000 0.988 0.011
D09.1 Other and unspecified urinary organs
0.000 0.988 0.011
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.000 0.988 0.011
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.000 0.989 0.011
C41.1 Mandible
0.000 0.989 0.011
C41.9 Bone and articular cartilage, unspecified
0.000 0.989 0.011
C70 Malignant neoplasm of meninges
0.000 0.989 0.011
C64-C68 Malignant neoplasms of urinary tract
0.000 0.989 0.011
C50-C50 Malignant neoplasm of breast
0.000 0.989 0.011
C41.8 Overlapping lesion of bone and articular cartilage
0.000 0.989 0.010
C41.4 Pelvic bones, sacrum and coccyx
0.000 0.989 0.010
C41.3 Ribs, sternum and clavicle
0.000 0.989 0.010
C41.2 Vertebral column
0.000 0.989 0.010
C41.0 Bones of skull and face
0.000 0.989 0.010
C69.9 Eye, unspecified
0.000 0.990 0.010
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.000 0.990 0.010
C46 Kaposi's sarcoma
0.000 0.990 0.010
C69.0 Conjunctiva
0.000 0.990 0.010
C49 Malignant neoplasm of other connective and soft tissue
0.000 0.990 0.010
C45 Mesothelioma
0.000 0.990 0.010
C42.4 hematopoietic and reticuloendothelial systems: Hematopoietic system, NOS (ICD-O-3 specific)
0.000 0.990 0.010
C42.3 hematopoietic and reticuloendothelial systems: Reticuloendothelial system, NOS (ICD-O-3 specific)
0.000 0.990 0.010
C42.2 hematopoietic and reticuloendothelial systems: spleen (ICD-O-3 specific)
0.000 0.990 0.010
C42.1 hematopoietic and reticuloendothelial systems: bone marrow (ICD-O-3 specific)
0.000 0.990 0.010
C42.0 hematopoietic and reticuloendothelial systems: blood (ICD-O-3 specific)
0.000 0.990 0.010
C66 Malignant neoplasm of ureter
0.000 0.990 0.010
C97 Malignant neoplasms of independent (primary) multiple sites
0.000 0.990 0.009
D07.1 Vulva
0.000 0.990 0.009
C69.3 Choroid
0.000 0.991 0.009
C69.8 Overlapping lesion of eye and adnexa
0.000 0.991 0.009
C69.5 Lachrymal gland and duct
0.000 0.991 0.009
C69.4 Ciliary body
0.000 0.991 0.009
C69.2 Retina
0.000 0.991 0.009
C69.1 Cornea
0.000 0.991 0.009
C49.5 Connective and soft tissue of pelvis
0.000 0.991 0.009
C40.9 Bone and articular cartilage of limb, unspecified
0.000 0.991 0.009
C40.8 Overlapping lesion of bone and articular cartilage of limbs
0.000 0.991 0.009
C40.3 Short bones of lower limb
0.000 0.991 0.009
C40.1 Short bones of upper limb
0.000 0.991 0.009
T43.0 Tricyclic and tetracyclic antidepressants
0.009 0.991 0.000
C69.6 Orbit
0.000 0.991 0.009
D05 Carcinoma in situ of breast
0.000 0.991 0.009
C49.9 Connective and soft tissue, unspecified
0.000 0.991 0.009
D06.7 Other parts of cervix
0.000 0.991 0.008
D06.1 Exocervix
0.000 0.991 0.008
C65 Malignant neoplasm of renal pelvis
0.000 0.991 0.009
C40.2 Long bones of lower limb
0.000 0.991 0.008
C72.0 Spinal cord
0.000 0.991 0.008
C40.0 Scapula and long bones of upper limb
0.000 0.991 0.008
C72.9 Central nervous system, unspecified
0.000 0.992 0.008
C72.8 Overlapping lesion of brain and other parts of central nervous system
0.000 0.992 0.008
C72.5 Other and unspecified cranial nerves
0.000 0.992 0.008
C72.4 Acoustic nerve
0.000 0.992 0.008
C72.3 Optic nerve
0.000 0.992 0.008
C72.2 Olfactory nerve
0.000 0.992 0.008
C72.1 Cauda equina
0.000 0.992 0.008
C49.4 Connective and soft tissue of abdomen
0.000 0.992 0.008
C70.0 Cerebral meninges
0.000 0.992 0.008
C70.9 Meninges, unspecified
0.000 0.992 0.008
C70.1 Spinal meninges
0.000 0.992 0.008
C45.9 Mesothelioma, unspecified
0.000 0.992 0.008
E04.9 Non-toxic goitre, unspecified
0.008 0.992 0.000
C49.3 Connective and soft tissue of thorax
0.000 0.992 0.008
C75 Malignant neoplasm of other endocrine glands and related structures
0.000 0.992 0.008
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.008 0.992 0.000
C45.0 Mesothelioma of pleura
0.000 0.992 0.008
T36-T50 Poisoning by drugs, medicaments and biological substances
0.008 0.992 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.008 0.992 0.000
C46.9 Kaposi's sarcoma, unspecified
0.000 0.992 0.007
C46.8 Kaposi's sarcoma of multiple organs
0.000 0.992 0.007
C46.7 Kaposi's sarcoma of other sites
0.000 0.992 0.007
C46.3 Kaposi's sarcoma of lymph nodes
0.000 0.992 0.007
C46.2 Kaposi's sarcoma of palate
0.000 0.992 0.007
C46.1 Kaposi's sarcoma of soft tissue
0.000 0.992 0.007
C46.0 Kaposi's sarcoma of skin
0.000 0.992 0.007
C47.9 Peripheral nerves and autonomic nervous system, unspecified
0.000 0.992 0.007
C47.8 Overlapping lesion of peripheral nerves and autonomic nervous system
0.000 0.992 0.007
C47.6 Peripheral nerves of trunk, unspecified
0.000 0.992 0.007
C47.5 Peripheral nerves of pelvis
0.000 0.992 0.007
C47.4 Peripheral nerves of abdomen
0.000 0.992 0.007
C47.3 Peripheral nerves of thorax
0.000 0.992 0.007
C47.2 Peripheral nerves of lower limb, including hip
0.000 0.992 0.007
C47.1 Peripheral nerves of upper limb, including shoulder
0.000 0.992 0.007
C47.0 Peripheral nerves of head, face and neck
0.000 0.992 0.007
C74 Malignant neoplasm of adrenal gland
0.000 0.992 0.007
T45.5 Anticoagulants
0.008 0.992 0.000
C49.8 Overlapping lesion of connective and soft tissue
0.000 0.992 0.007
C49.6 Connective and soft tissue of trunk, unspecified
0.000 0.992 0.007
C68 Malignant neoplasm of other and unspecified urinary organs
0.000 0.992 0.008
C45.2 Mesothelioma of pericardium
0.000 0.992 0.007
C45.1 Mesothelioma of peritoneum
0.000 0.992 0.007
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.007 0.993 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.007 0.993 0.000
C60-C63 Malignant neoplasms of male genital organs
0.000 0.993 0.007
I20.1 Angina pectoris with documented spasm
0.007 0.993 0.000
D05.7 Other carcinoma in situ of breast
0.000 0.993 0.007
D06.0 Endocervix
0.000 0.993 0.007
T46 Poisoning by agents primarily affecting the cardiovascular system
0.007 0.993 0.000
T45.2 Vitamins, not elsewhere classified
0.007 0.993 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.007 0.993 0.000
T43.6 Psychostimulants with abuse potential
0.007 0.993 0.000
L57.0 Actinic keratosis
0.000 0.993 0.007
M77.91 Enthesopathy, unspecified (Shoulder region)
0.000 0.993 0.007
T50.9 Other and unspecified drugs, medicaments and biological substances
0.007 0.993 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.007 0.993 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.007 0.993 0.000
C49.2 Connective and soft tissue of lower limb, including hip
0.000 0.993 0.007
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.993 0.007
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.007 0.993 0.000
T50.8 Diagnostic agents
0.006 0.994 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.000 0.994 0.006
D05.0 Lobular carcinoma in situ
0.000 0.994 0.006
C09.9 Tonsil, unspecified
0.006 0.994 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.006 0.994 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.006 0.994 0.000
C75.9 Endocrine gland, unspecified
0.000 0.994 0.006
C75.8 Pluriglandular involvement, unspecified
0.000 0.994 0.006
C75.5 Aortic body and other paraganglia
0.000 0.994 0.006
C75.4 Carotid body
0.000 0.994 0.006
C75.3 Pineal gland
0.000 0.994 0.006
C75.2 Craniopharyngeal duct
0.000 0.994 0.006
C75.0 Parathyroid gland
0.000 0.994 0.006
T43.9 Psychotropic drug, unspecified
0.006 0.994 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.006 0.994 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.006 0.994 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.006 0.994 0.000
C45.7 Mesothelioma of other sites
0.000 0.994 0.006
T37.8 Other specified systemic anti-infectives and antiparasitics
0.006 0.994 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.006 0.994 0.000
T45.9 Primarily systemic and haematological agent, unspecified
0.006 0.994 0.000
T45.8 Other primarily systemic and haematological agents
0.006 0.994 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.006 0.994 0.000
T45.6 Fibrinolysis-affecting drugs
0.006 0.994 0.000
T45.4 Iron and its compounds
0.006 0.994 0.000
T45.3 Enzymes, not elsewhere classified
0.006 0.994 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.006 0.994 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.006 0.994 0.000
C68.0 Urethra
0.000 0.994 0.006
T46.1 Calcium-channel blockers
0.006 0.994 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.006 0.994 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.006 0.994 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.006 0.994 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.006 0.994 0.000
C74.1 Medulla of adrenal gland
0.000 0.994 0.006
C74.0 Cortex of adrenal gland
0.000 0.994 0.006
T43.2 Other and unspecified antidepressants
0.006 0.994 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.006 0.994 0.000
C68.8 Overlapping lesion of urinary organs
0.000 0.994 0.006
C68.1 Paraurethral glands
0.000 0.994 0.006
C49.0 Connective and soft tissue of head, face and neck
0.000 0.994 0.005
C75.1 Pituitary gland
0.000 0.994 0.005
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.006 0.994 0.000
T36 Poisoning by systemic antibiotics
0.006 0.994 0.000
T50.7 Analeptics and opioid receptor antagonists
0.005 0.994 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.005 0.994 0.000
T50.5 Appetite depressants
0.005 0.994 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.005 0.994 0.000
T50.1 Loop [high-ceiling] diuretics
0.005 0.994 0.000
T50.0 Mineralocorticoids and their antagonists
0.005 0.994 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.006 0.994 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.000 0.994 0.006
C63 Malignant neoplasm of other and unspecified male genital organs
0.000 0.994 0.005
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.994 0.005
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.005 0.995 0.000
T38.1 Thyroid hormones and substitutes
0.005 0.995 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.005 0.995 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.005 0.995 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.005 0.995 0.000
T46.7 Peripheral vasodilators
0.005 0.995 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.005 0.995 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.005 0.995 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.005 0.995 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.005 0.995 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.005 0.995 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.005 0.995 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.005 0.995 0.000
T44.0 Anticholinesterase agents
0.005 0.995 0.000
C68.9 Urinary organ, unspecified
0.000 0.995 0.005
T50.4 Drugs affecting uric acid metabolism
0.005 0.995 0.000
H35.8 Other specified retinal disorders
0.005 0.995 0.000
T45.0 Antiallergic and antiemetic drugs
0.005 0.995 0.000
C60 Malignant neoplasm of penis
0.000 0.995 0.005
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.005 0.995 0.000
T37.5 Antiviral drugs
0.005 0.995 0.000
T37.4 Anthelminthics
0.005 0.995 0.000
T37.3 Other antiprotozoal drugs
0.005 0.995 0.000
T37.2 Antimalarials and drugs acting on other blood protozoa
0.005 0.995 0.000
T37.1 Antimycobacterial drugs
0.005 0.995 0.000
T37.0 Sulphonamides
0.005 0.995 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.005 0.995 0.000
C74.9 Adrenal gland, unspecified
0.000 0.995 0.005
T46.3 Coronary vasodilators, not elsewhere classified
0.005 0.995 0.000
D09.0 Bladder
0.000 0.995 0.005
T38.9 Other and unspecified hormone antagonists
0.005 0.995 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.005 0.995 0.000
T38.7 Androgens and anabolic congeners
0.005 0.995 0.000
T38.5 Other oestrogens and progestogens
0.005 0.995 0.000
T38.4 Oral contraceptives
0.005 0.995 0.000
T38.2 Antithyroid drugs
0.005 0.995 0.000
T38.0 Glucocorticoids and synthetic analogues
0.005 0.995 0.000
C48.8 Overlapping lesion of retroperitoneum and peritoneum
0.000 0.995 0.005
T48.6 Antiasthmatics, not elsewhere classified
0.005 0.995 0.000
C49.1 Connective and soft tissue of upper limb, including shoulder
0.001 0.995 0.004
T42.1 Iminostilbenes
0.005 0.995 0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.004 0.995 0.000
T48.5 Anti-common-cold drugs
0.004 0.995 0.000
T48.4 Expectorants
0.004 0.995 0.000
T48.3 Antitussives
0.004 0.995 0.000
T48.2 Other and unspecified agents primarily acting on muscles
0.004 0.995 0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.004 0.995 0.000
T48.0 Oxytocic drugs
0.004 0.995 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.004 0.995 0.000
T41.5 Therapeutic gases
0.004 0.995 0.000
T41.4 Anaesthetic, unspecified
0.004 0.995 0.000
T41.3 Local anaesthetics
0.004 0.995 0.000
T41.2 Other and unspecified general anaesthetics
0.004 0.995 0.000
T41.1 Intravenous anaesthetics
0.004 0.995 0.000
T41.0 Inhaled anaesthetics
0.004 0.995 0.000
T49.9 Topical agent, unspecified
0.004 0.995 0.000
T49.8 Other topical agents
0.004 0.995 0.000
T49.7 Dental drugs, topically applied
0.004 0.995 0.000
T49.6 Otorhinolaryngological drugs and preparations
0.004 0.995 0.000
T49.5 Ophthalmological drugs and preparations
0.004 0.995 0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.004 0.995 0.000
T49.3 Emollients, demulcents and protectants
0.004 0.995 0.000
T49.2 Local astringents and local detergents
0.004 0.995 0.000
T49.1 Antipruritics
0.004 0.995 0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.004 0.995 0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.004 0.995 0.000
T47.8 Other agents primarily affecting the gastro-intestinal system
0.004 0.995 0.000
T47.7 Emetics
0.004 0.995 0.000
T47.6 Antidiarrhoeal drugs
0.004 0.995 0.000
T47.5 Digestants
0.004 0.995 0.000
T47.4 Other laxatives
0.004 0.995 0.000
T47.3 Saline and osmotic laxatives
0.004 0.995 0.000
T47.2 Stimulant laxatives
0.004 0.995 0.000
T47.0 Histamine H(2)-receptor antagonists
0.004 0.995 0.000
C48.0 Retroperitoneum
0.000 0.995 0.004
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.004 0.995 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.004 0.995 0.000
T42.3 Barbiturates
0.004 0.995 0.000
T42.2 Succinimides and oxazolidinediones
0.004 0.995 0.000
N35.9 Urethral stricture, unspecified
0.004 0.996 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.004 0.996 0.000
C09 Malignant neoplasm of tonsil
0.003 0.996 0.001
C38 Malignant neoplasm of heart, mediastinum and pleura
0.000 0.996 0.004
C37 Malignant neoplasm of thymus
0.000 0.996 0.004
C73 Malignant neoplasm of thyroid gland
0.000 0.996 0.004
C62 Malignant neoplasm of testis
0.000 0.996 0.004
T36.9 Systemic antibiotic, unspecified
0.004 0.996 0.000
T36.8 Other systemic antibiotics
0.004 0.996 0.000
T36.7 Antifungal antibiotics, systemically used
0.004 0.996 0.000
T36.6 Rifamycins
0.004 0.996 0.000
T36.5 Aminoglycosides
0.004 0.996 0.000
T36.4 Tetracyclines
0.004 0.996 0.000
T36.3 Macrolides
0.004 0.996 0.000
T36.2 Chloramphenicol group
0.004 0.996 0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.004 0.996 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.000 0.996 0.004
C31 Malignant neoplasm of accessory sinuses
0.000 0.996 0.004
C63.9 Male genital organ, unspecified
0.000 0.996 0.004
C63.8 Overlapping lesion of male genital organs
0.000 0.996 0.004
C63.7 Other specified male genital organs
0.000 0.996 0.004
C63.2 Scrotum
0.000 0.996 0.004
C63.1 Spermatic cord
0.000 0.996 0.004
C63.0 Epididymis
0.000 0.996 0.004
I60.9 Subarachnoid haemorrhage, unspecified
0.004 0.996 0.000
L57.5 Actinic granuloma
0.000 0.996 0.004
L57.3 Poikiloderma of Civatte
0.000 0.996 0.004
L57.2 Cutis rhomboidalis nuchae
0.000 0.996 0.004
L57.1 Actinic reticuloid
0.000 0.996 0.004
M25.4 Effusion of joint
0.004 0.996 0.000
T36.0 Penicillins
0.004 0.996 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.004 0.996 0.000
C33 Malignant neoplasm of trachea
0.000 0.996 0.004
C60.8 Overlapping lesion of penis
0.000 0.996 0.004
C60.2 Body of penis
0.000 0.996 0.004
C60.0 Prepuce
0.000 0.996 0.004
M19.90 Arthrosis, unspecified (Multiple sites)
0.000 0.996 0.004
T43.3 Phenothiazine antipsychotics and neuroleptics
0.004 0.996 0.000
C48.2 Peritoneum, unspecified
0.000 0.996 0.004
M25.45 Effusion of joint (Pelvic region and thigh)
0.004 0.996 0.000
C60.1 Glans penis
0.000 0.996 0.004
T42.4 Benzodiazepines
0.004 0.996 0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure
0.000 0.996 0.004
K81.0 Acute cholecystitis
0.004 0.996 0.000
R06.5 Mouth breathing
0.000 0.996 0.004
C30 Malignant neoplasm of nasal cavity and middle ear
0.000 0.996 0.003
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.001 0.996 0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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