TreeWAS – Variant ID: rs12665338

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
K90.0 Coeliac disease	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	1.000	0.000	0.000
L40.5 Arthropathic psoriasis	1.000	0.000	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	1.000	0.000	0.000
L40 Psoriasis	1.000	0.000	0.000
R31 Unspecified haematuria	1.000	0.000	0.000
E03 Other hypothyroidism	0.000	0.001	0.999
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.002	0.998
E05.9 Thyrotoxicosis, unspecified	0.000	0.002	0.998
E00-E07 Disorders of thyroid gland	0.000	0.003	0.997
L40.0 Psoriasis vulgaris	0.997	0.003	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.016	0.984
M45 Ankylosing spondylitis	0.968	0.032	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.958	0.042	0.000
M07.3 Other psoriatic arthropathies	0.907	0.093	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.093	0.907
L40.4 Guttate psoriasis	0.906	0.094	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.898	0.102	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.893	0.107	0.000
E07 Other disorders of thyroid	0.000	0.116	0.884
G35 Multiple sclerosis	0.000	0.148	0.852
M07.36 Other psoriatic arthropathies (Lower leg)	0.845	0.155	0.000
M35.0 Sicca syndrome [Sjogren]	0.000	0.164	0.836
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.834	0.166	0.000
E03.8 Other specified hypothyroidism	0.000	0.194	0.806
E07.8 Other specified disorders of thyroid	0.000	0.199	0.801
K90 Intestinal malabsorption	0.000	0.220	0.780
M45.X2 Ankylosing spondylitis (Cervical region)	0.779	0.221	0.000
L40.8 Other psoriasis	0.776	0.224	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.772	0.228	0.000
L40.1 Generalised pustular psoriasis	0.760	0.240	0.000
M07.38 Other psoriatic arthropathies (Other)	0.749	0.251	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.733	0.267	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.280	0.720
L40.2 Acrodermatitis continua	0.717	0.283	0.000
E03.5 Myxoedema coma	0.000	0.284	0.716
E03.4 Atrophy of thyroid (acquired)	0.000	0.284	0.716
E03.3 Postinfectious hypothyroidism	0.000	0.284	0.716
E05.5 Thyroid crisis or storm	0.000	0.284	0.715
E05.4 Thyrotoxicosis factitia	0.000	0.284	0.715
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.284	0.715
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.285	0.715
E00 Congenital iodine-deficiency syndrome	0.000	0.285	0.715
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.694	0.306	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.694	0.306	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.694	0.306	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.694	0.306	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.694	0.306	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.694	0.306	0.000
K90.9 Intestinal malabsorption, unspecified	0.000	0.308	0.692
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.678	0.321	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.671	0.329	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.343	0.657
E03.1 Congenital hypothyroidism without goitre	0.000	0.348	0.652
M07.33 Other psoriatic arthropathies (Forearm)	0.650	0.349	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.650	0.349	0.000
L40.3 Pustulosis palmaris et plantaris	0.639	0.361	0.000
E07.9 Disorder of thyroid, unspecified	0.000	0.362	0.638
E07.1 Dyshormogenetic goitre	0.000	0.366	0.634
E07.0 Hypersecretion of calcitonin	0.000	0.366	0.634
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.373	0.627
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.378	0.621
K90.8 Other intestinal malabsorption	0.000	0.392	0.608
E05.8 Other thyrotoxicosis	0.000	0.429	0.571
K90.3 Pancreatic steatorrhoea	0.000	0.440	0.559
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.440	0.559
K90.1 Tropical sprue	0.000	0.440	0.559
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.487	0.513
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.487	0.513
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.487	0.513
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.487	0.513
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.487	0.513
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.487	0.513
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.487	0.513
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.487	0.513
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.489	0.511
L40-L45 Papulosquamous disorders	0.476	0.524	0.000
M07 Psoriatic and enteropathic arthropathies	0.438	0.562	0.000
E06 Thyroiditis	0.001	0.613	0.387
L41 Parapsoriasis	0.372	0.628	0.000
L42 Pityriasis rosea	0.361	0.639	0.000
L44 Other papulosquamous disorders	0.344	0.656	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.341	0.659	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.663	0.337
M07.5 Arthropathy in ulcerative colitis	0.314	0.686	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.314	0.686	0.000
M07.2 Psoriatic spondylitis	0.314	0.686	0.000
M07.1 Arthritis mutilans	0.314	0.686	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.314	0.686	0.000
L43 Lichen planus	0.311	0.689	0.000
L41.1 Pityriasis lichenoides chronica	0.298	0.702	0.000
E06.3 Autoimmune thyroiditis	0.000	0.704	0.296
E27.1 Primary adrenocortical insufficiency	0.000	0.705	0.295
M07.6 Other enteropathic arthropathies	0.290	0.710	0.000
E06.4 Drug-induced thyroiditis	0.001	0.722	0.277
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.001	0.722	0.277
E06.0 Acute thyroiditis	0.001	0.722	0.277
L41.9 Parapsoriasis, unspecified	0.267	0.733	0.000
L41.8 Other parapsoriasis	0.267	0.733	0.000
L41.5 Retiform parapsoriasis	0.267	0.733	0.000
L41.4 Large plaque parapsoriasis	0.267	0.733	0.000
L41.3 Small plaque parapsoriasis	0.267	0.733	0.000
L41.2 Lymphomatoid papulosis	0.267	0.733	0.000
L41.0 Pityriasis lichenoides et varioliformis acuta	0.267	0.733	0.000
L44.0 Pityriasis rubra pilaris	0.249	0.751	0.000
G36 Other acute disseminated demyelination	0.000	0.753	0.247
L44.9 Papulosquamous disorder, unspecified	0.246	0.753	0.000
L44.8 Other specified papulosquamous disorders	0.246	0.753	0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.246	0.753	0.000
L44.3 Lichen ruber moniliformis	0.246	0.753	0.000
L44.2 Lichen striatus	0.246	0.753	0.000
L44.1 Lichen nitidus	0.246	0.753	0.000
E27 Other disorders of adrenal gland	0.000	0.759	0.241
L43.8 Other lichen planus	0.228	0.772	0.000
E06.5 Other chronic thyroiditis	0.001	0.774	0.225
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.225	0.775	0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.225	0.775	0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.225	0.775	0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.225	0.775	0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.225	0.775	0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.225	0.775	0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.225	0.775	0.000
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm	0.225	0.775	0.000
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region	0.225	0.775	0.000
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)	0.225	0.775	0.000
M07.19 Arthritis mutilans (Site unspecified)	0.225	0.775	0.000
M07.18 Arthritis mutilans (Other)	0.225	0.775	0.000
M07.17 Arthritis mutilans (Ankle and foot)	0.225	0.775	0.000
M07.16 Arthritis mutilans (Lower leg)	0.225	0.775	0.000
M07.15 Arthritis mutilans (Pelvic region and thigh)	0.225	0.775	0.000
M07.14 Arthritis mutilans (Hand)	0.225	0.775	0.000
M07.13 Arthritis mutilans (Forearm)	0.225	0.775	0.000
M07.12 Arthritis mutilans (Upper arm)	0.225	0.775	0.000
M07.11 Arthritis mutilans (Shoulder region)	0.225	0.775	0.000
M07.10 Arthritis mutilans (Multiple sites)	0.225	0.775	0.000
M07.29 Psoriatic spondylitis (Site unspecified)	0.225	0.775	0.000
M07.28 Psoriatic spondylitis (Other)	0.225	0.775	0.000
M07.27 Psoriatic spondylitis (Ankle and foot)	0.225	0.775	0.000
M07.26 Psoriatic spondylitis (Lower leg)	0.225	0.775	0.000
M07.25 Psoriatic spondylitis (Pelvic region and thigh)	0.225	0.775	0.000
M07.24 Psoriatic spondylitis (Hand)	0.225	0.775	0.000
M07.23 Psoriatic spondylitis (Forearm)	0.225	0.775	0.000
M07.22 Psoriatic spondylitis (Upper arm)	0.225	0.775	0.000
M07.21 Psoriatic spondylitis (Shoulder region)	0.225	0.775	0.000
M07.20 Psoriatic spondylitis (Multiple sites)	0.225	0.775	0.000
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)	0.225	0.775	0.000
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)	0.225	0.775	0.000
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)	0.225	0.775	0.000
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)	0.225	0.775	0.000
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)	0.225	0.775	0.000
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)	0.225	0.775	0.000
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)	0.225	0.775	0.000
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)	0.225	0.775	0.000
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)	0.225	0.775	0.000
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)	0.225	0.775	0.000
M07.59 Arthropathy in ulcerative colitis (Site unspecified)	0.225	0.775	0.000
M07.58 Arthropathy in ulcerative colitis (Other)	0.225	0.775	0.000
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)	0.225	0.775	0.000
M07.56 Arthropathy in ulcerative colitis (Lower leg)	0.225	0.775	0.000
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)	0.225	0.775	0.000
M07.54 Arthropathy in ulcerative colitis (Hand)	0.225	0.775	0.000
M07.53 Arthropathy in ulcerative colitis (Forearm)	0.225	0.775	0.000
M07.52 Arthropathy in ulcerative colitis (Upper arm)	0.225	0.775	0.000
M07.51 Arthropathy in ulcerative colitis (Shoulder region)	0.225	0.775	0.000
M07.50 Arthropathy in ulcerative colitis (Multiple sites)	0.225	0.775	0.000
L43.3 Subacute (active) lichen planus	0.223	0.777	0.000
L43.2 Lichenoid drug reaction	0.223	0.777	0.000
L43.1 Bullous lichen planus	0.223	0.777	0.000
E04 Other non-toxic goitre	0.000	0.778	0.222
L43.0 Hypertrophic lichen planus	0.211	0.788	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.791	0.209
M07.68 Other enteropathic arthropathies (Other)	0.208	0.792	0.000
M07.67 Other enteropathic arthropathies (Ankle and foot)	0.208	0.792	0.000
M07.66 Other enteropathic arthropathies (Lower leg)	0.208	0.792	0.000
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)	0.208	0.792	0.000
M07.64 Other enteropathic arthropathies (Hand)	0.208	0.792	0.000
M07.63 Other enteropathic arthropathies (Forearm)	0.208	0.792	0.000
M07.62 Other enteropathic arthropathies (Upper arm)	0.208	0.792	0.000
M07.61 Other enteropathic arthropathies (Shoulder region)	0.208	0.792	0.000
M07.60 Other enteropathic arthropathies (Multiple sites)	0.208	0.792	0.000
E27.2 Addisonian crisis	0.000	0.793	0.207
L43.9 Lichen planus, unspecified	0.199	0.801	0.000
E20-E35 Disorders of other endocrine glands	0.000	0.805	0.195
E06.1 Subacute thyroiditis	0.001	0.805	0.194
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.807	0.193
M07.69 Other enteropathic arthropathies (Site unspecified)	0.184	0.815	0.000
E06.9 Thyroiditis, unspecified	0.001	0.816	0.183
G36.0 Neuromyelitis optica [Devic]	0.000	0.817	0.182
E04.0 Non-toxic diffuse goitre	0.000	0.821	0.179
G36.9 Acute disseminated demyelination, unspecified	0.000	0.823	0.177
G36.8 Other specified acute disseminated demyelination	0.000	0.823	0.177
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.000	0.823	0.177
E28 Ovarian dysfunction	0.000	0.823	0.177
E27.5 Adrenomedullary hyperfunction	0.000	0.827	0.173
E27.0 Other adrenocortical overactivity	0.000	0.827	0.173
E20 Hypoparathyroidism	0.000	0.830	0.170
D69.6 Thrombocytopenia, unspecified	0.000	0.833	0.167
E28.3 Primary ovarian failure	0.000	0.837	0.162
E27.8 Other specified disorders of adrenal gland	0.000	0.838	0.162
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.839	0.161
G30-G32 Other degenerative diseases of the nervous system	0.000	0.840	0.160
E04.8 Other specified non-toxic goitre	0.000	0.840	0.159
G31.2 Degeneration of nervous system due to alcohol	0.000	0.844	0.156
Chapter VI Diseases of the nervous system	0.000	0.844	0.156
M05-M14 Inflammatory polyarthropathies	0.155	0.845	0.000
E20.9 Hypoparathyroidism, unspecified	0.000	0.848	0.152
M05 Seropositive rheumatoid arthritis	0.146	0.854	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.858	0.142
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.859	0.140
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.860	0.140
E32 Diseases of thymus	0.000	0.860	0.140
E31 Polyglandular dysfunction	0.000	0.860	0.140
E30 Disorders of puberty, not elsewhere classified	0.000	0.860	0.140
G00-G09 Inflammatory diseases of the central nervous system	0.000	0.860	0.140
M05.9 Seropositive rheumatoid arthritis, unspecified	0.139	0.861	0.000
G70-G73 Diseases of myoneural junction and muscle	0.000	0.862	0.138
G72 Other myopathies	0.000	0.866	0.134
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.867	0.133
E24 Cushing's syndrome	0.000	0.867	0.133
G30 Alzheimer's disease	0.000	0.867	0.133
E28.2 Polycystic ovarian syndrome	0.000	0.867	0.133
N48.4 Impotence of organic origin	0.132	0.868	0.000
G37 Other demyelinating diseases of central nervous system	0.000	0.868	0.131
G80-G83 Cerebral palsy and other paralytic syndromes	0.000	0.869	0.131
G09 Sequelae of inflammatory diseases of central nervous system	0.000	0.870	0.129
N48 Other disorders of penis	0.129	0.871	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.872	0.128
M35 Other systemic involvement of connective tissue	0.000	0.872	0.128
E25 Adrenogenital disorders	0.000	0.872	0.127
N48.2 Other inflammatory disorders of penis	0.127	0.873	0.000
G31.8 Other specified degenerative diseases of nervous system	0.000	0.873	0.127
E28.9 Ovarian dysfunction, unspecified	0.000	0.873	0.127
E28.8 Other ovarian dysfunction	0.000	0.873	0.127
E28.1 Androgen excess	0.000	0.873	0.127
E28.0 Oestrogen excess	0.000	0.873	0.127
G72.9 Myopathy, unspecified	0.000	0.875	0.125
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.124	0.876	0.000
E20.8 Other hypoparathyroidism	0.000	0.878	0.122
E20.1 Pseudohypoparathyroidism	0.000	0.878	0.122
E20.0 Idiopathic hypoparathyroidism	0.000	0.878	0.122
G31.0 Circumscribed brain atrophy	0.000	0.881	0.119
G00 Bacterial meningitis, not elsewhere classified	0.000	0.881	0.119
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.116	0.884	0.000
E23 Hypofunction and other disorders of pituitary gland	0.000	0.884	0.116
G31.1 Senile degeneration of brain, not elsewhere classified	0.000	0.884	0.116
G82 Paraplegia and tetraplegia	0.000	0.885	0.115
M08 Juvenile arthritis	0.115	0.885	0.000
M12 Other specific arthropathies	0.114	0.886	0.000
M05.1 Rheumatoid lung disease	0.114	0.886	0.000
G06 Intracranial and intraspinal abscess and granuloma	0.000	0.887	0.113
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.887	0.113
G72.8 Other specified myopathies	0.000	0.887	0.113
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.113	0.887	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.112	0.888	0.000
G82.1 Spastic paraplegia	0.000	0.889	0.111
N48.1 Balanoposthitis	0.111	0.889	0.000
N48.8 Other specified disorders of penis	0.111	0.889	0.000
E27.9 Disorder of adrenal gland, unspecified	0.000	0.890	0.110
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.109	0.891	0.000
E40-E46 Malnutrition	0.000	0.891	0.109
M14 Arthropathies in other diseases classified elsewhere	0.108	0.892	0.000
E24.2 Drug-induced Cushing's syndrome	0.000	0.892	0.108
G30.0 Alzheimer's disease with early onset	0.000	0.892	0.108
G72.1 Alcoholic myopathy	0.000	0.893	0.107
E26 Hyperaldosteronism	0.000	0.894	0.106
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.106	0.894	0.000
E29 Testicular dysfunction	0.000	0.894	0.106
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.105	0.895	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.105	0.895	0.000
M05.0 Felty's syndrome	0.105	0.895	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.104	0.895	0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.000	0.896	0.104
E34 Other endocrine disorders	0.000	0.896	0.104
G72.0 Drug-induced myopathy	0.000	0.896	0.104
N48.9 Disorder of penis, unspecified	0.103	0.897	0.000
E16 Other disorders of pancreatic internal secretion	0.000	0.897	0.103
M05.8 Other seropositive rheumatoid arthritis	0.102	0.898	0.000
E23.2 Diabetes insipidus	0.000	0.898	0.102
E15 Nondiabetic hypoglycaemic coma	0.000	0.899	0.101
E30.9 Disorder of puberty, unspecified	0.000	0.899	0.101
E30.8 Other disorders of puberty	0.000	0.899	0.101
E30.1 Precocious puberty	0.000	0.899	0.101
E30.0 Delayed puberty	0.000	0.899	0.101
E31.9 Polyglandular dysfunction, unspecified	0.000	0.899	0.101
E31.8 Other polyglandular dysfunction	0.000	0.899	0.101
E31.1 Polyglandular hyperfunction	0.000	0.899	0.101
E31.0 Autoimmune polyglandular failure	0.000	0.899	0.101
E32.9 Disease of thymus, unspecified	0.000	0.899	0.101
E32.8 Other diseases of thymus	0.000	0.899	0.101
E32.1 Abscess of thymus	0.000	0.899	0.101
E32.0 Persistent hyperplasia of thymus	0.000	0.899	0.101
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.899	0.101
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.899	0.101
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.899	0.101
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.101	0.899	0.000
G30.1 Alzheimer's disease with late onset	0.000	0.899	0.100
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.000	0.899	0.100
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.000	0.899	0.100
M06 Other rheumatoid arthritis	0.100	0.900	0.000
E24.8 Other Cushing's syndrome	0.000	0.900	0.100
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.100	0.900	0.000
G83 Other paralytic syndromes	0.000	0.900	0.100
M05.2 Rheumatoid vasculitis	0.099	0.900	0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.000	0.901	0.099
G30.8 Other Alzheimer's disease	0.000	0.901	0.099
G00.9 Bacterial meningitis, unspecified	0.000	0.902	0.098
G01 Meningitis in bacterial diseases classified elsewhere	0.000	0.902	0.098
E04.9 Non-toxic goitre, unspecified	0.000	0.902	0.098
G37.8 Other specified demyelinating diseases of central nervous system	0.000	0.903	0.097
G72.3 Periodic paralysis	0.000	0.904	0.096
G72.2 Myopathy due to other toxic agents	0.000	0.904	0.096
G06.1 Intraspinal abscess and granuloma	0.000	0.904	0.096
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere	0.000	0.904	0.095
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.904	0.095
E24.3 Ectopic ACTH syndrome	0.000	0.904	0.095
E24.1 Nelson's syndrome	0.000	0.904	0.095
G03 Meningitis due to other and unspecified causes	0.000	0.905	0.095
G30.9 Alzheimer's disease, unspecified	0.000	0.905	0.095
G37.5 Concentric sclerosis [Balo]	0.000	0.905	0.094
G37.4 Subacute necrotising myelitis	0.000	0.905	0.094
G37.2 Central pontine myelinolysis	0.000	0.905	0.094
G37.1 Central demyelination of corpus callosum	0.000	0.905	0.094
G37.0 Diffuse sclerosis	0.000	0.905	0.094
G83.4 Cauda equina syndrome	0.000	0.907	0.093
N48.6 Balanitis xerotica obliterans	0.093	0.907	0.000
M11 Other crystal arthropathies	0.093	0.907	0.000
N42.8 Other specified disorders of prostate	0.093	0.907	0.000
M35.8 Other specified systemic involvement of connective tissue	0.000	0.908	0.092
G00.2 Streptococcal meningitis	0.000	0.908	0.092
E04.2 Non-toxic multinodular goitre	0.000	0.908	0.092
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.000	0.908	0.092
M35.9 Systemic involvement of connective tissue, unspecified	0.000	0.908	0.092
M35.6 Relapsing panniculitis [Weber-Christian]	0.000	0.908	0.092
M35.5 Multifocal fibrosclerosis	0.000	0.908	0.092
M35.4 Diffuse (eosinophilic) fasciitis	0.000	0.908	0.092
E25.9 Adrenogenital disorder, unspecified	0.000	0.908	0.091
E25.8 Other adrenogenital disorders	0.000	0.908	0.091
D69 Purpura and other haemorrhagic conditions	0.000	0.909	0.091
M13 Other arthritis	0.090	0.910	0.000
G81 Hemiplegia	0.000	0.910	0.090
M35.7 Hypermobility syndrome	0.000	0.911	0.089
M12.2 Villonodular synovitis (pigmented)	0.089	0.911	0.000
M35.2 Behcet's disease	0.000	0.911	0.089
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.089	0.911	0.000
M05.19 Rheumatoid lung disease (Site unspecified)	0.089	0.911	0.000
G82.5 Tetraplegia, unspecified	0.000	0.912	0.088
N42 Other disorders of prostate	0.088	0.912	0.000
M06.3 Rheumatoid nodule	0.088	0.912	0.000
G72.4 Inflammatory myopathy, not elsewhere classified	0.000	0.912	0.088
E24.0 Pituitary-dependent Cushing's disease	0.000	0.912	0.087
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.913	0.087
G00.1 Pneumococcal meningitis	0.000	0.913	0.087
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.000	0.913	0.087
G82.4 Spastic tetraplegia	0.000	0.914	0.086
M05.10 Rheumatoid lung disease (Multiple sites)	0.085	0.914	0.000
M08.0 Juvenile rheumatoid arthritis	0.085	0.915	0.000
G00.8 Other bacterial meningitis	0.000	0.915	0.085
G00.3 Staphylococcal meningitis	0.000	0.915	0.085
G00.0 Haemophilus meningitis	0.000	0.915	0.085
G80 Infantile cerebral palsy	0.000	0.915	0.085
G06.0 Intracranial abscess and granuloma	0.000	0.915	0.085
E34.8 Other specified endocrine disorders	0.000	0.916	0.084
N42.2 Atrophy of prostate	0.084	0.916	0.000
E50-E64 Other nutritional deficiencies	0.000	0.917	0.083
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.917	0.083
E23.1 Drug-induced hypopituitarism	0.000	0.917	0.083
G83.9 Paralytic syndrome, unspecified	0.000	0.917	0.083
E23.6 Other disorders of pituitary gland	0.000	0.917	0.083
G82.3 Flaccid tetraplegia	0.000	0.917	0.083
M08.9 Juvenile arthritis, unspecified	0.082	0.917	0.000
M08.8 Other juvenile arthritis	0.082	0.917	0.000
M08.4 Pauciarticular juvenile arthritis	0.082	0.917	0.000
M08.3 Juvenile polyarthritis (seronegative)	0.082	0.917	0.000
M08.2 Juvenile arthritis with systemic onset	0.082	0.917	0.000
M08.1 Juvenile ankylosing spondylitis	0.082	0.917	0.000
M12.8 Other specific arthropathies, not elsewhere classified	0.082	0.918	0.000
M12.4 Intermittent hydrarthrosis	0.082	0.918	0.000
M12.1 Kaschin-Beck disease	0.082	0.918	0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.082	0.918	0.000
M05.18 Rheumatoid lung disease (Other)	0.082	0.918	0.000
M05.17 Rheumatoid lung disease (Ankle and foot)	0.082	0.918	0.000
M05.16 Rheumatoid lung disease (Lower leg)	0.082	0.918	0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.082	0.918	0.000
M05.14 Rheumatoid lung disease (Hand)	0.082	0.918	0.000
M05.13 Rheumatoid lung disease (Forearm)	0.082	0.918	0.000
M05.12 Rheumatoid lung disease (Upper arm)	0.082	0.918	0.000
M05.11 Rheumatoid lung disease (Shoulder region)	0.082	0.918	0.000
N48.3 Priapism	0.082	0.918	0.000
G71 Primary disorders of muscles	0.000	0.919	0.081
M12.3 Palindromic rheumatism	0.081	0.919	0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.080	0.920	0.000
M09.2 Juvenile arthritis in ulcerative colitis	0.080	0.920	0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.080	0.920	0.000
M09.0 Juvenile arthritis in psoriasis	0.080	0.920	0.000
N48.5 Ulcer of penis	0.079	0.920	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.921	0.079
M14.2 Diabetic arthropathy	0.079	0.921	0.000
G02.0 Meningitis in viral diseases classified elsewhere	0.000	0.921	0.079
M12.5 Traumatic arthropathy	0.078	0.921	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.922	0.078
E45 Retarded development following protein-energy malnutrition	0.000	0.922	0.078
E43 Unspecified severe protein-energy malnutrition	0.000	0.922	0.078
E42 Marasmic kwashiorkor	0.000	0.922	0.078
E41 Nutritional marasmus	0.000	0.922	0.078
E40 Kwashiorkor	0.000	0.922	0.078
C44.3 Skin of other and unspecified parts of face	0.000	0.922	0.078
M14.4 Arthropathy in amyloidosis	0.078	0.922	0.000
M14.3 Lipoid dermatoarthritis	0.078	0.922	0.000
M14.1 Crystal arthropathy in other metabolic disorders	0.078	0.922	0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.078	0.922	0.000
M35.1 Other overlap syndromes	0.000	0.922	0.077
E26.8 Other hyperaldosteronism	0.000	0.924	0.076
E26.1 Secondary hyperaldosteronism	0.000	0.924	0.076
E29.8 Other testicular dysfunction	0.000	0.924	0.076
E29.0 Testicular hyperfunction	0.000	0.924	0.076
D69.4 Other primary thrombocytopenia	0.000	0.924	0.076
E16.2 Hypoglycaemia, unspecified	0.000	0.924	0.076
M05.09 Felty's syndrome (Site unspecified)	0.075	0.924	0.000
M05.08 Felty's syndrome (Other)	0.075	0.924	0.000
M05.07 Felty's syndrome (Ankle and foot)	0.075	0.924	0.000
M05.06 Felty's syndrome (Lower leg)	0.075	0.924	0.000
M05.05 Felty's syndrome (Pelvic region and thigh)	0.075	0.924	0.000
M05.04 Felty's syndrome (Hand)	0.075	0.924	0.000
M05.03 Felty's syndrome (Forearm)	0.075	0.924	0.000
M05.02 Felty's syndrome (Upper arm)	0.075	0.924	0.000
M05.01 Felty's syndrome (Shoulder region)	0.075	0.924	0.000
M05.00 Felty's syndrome (Multiple sites)	0.075	0.924	0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.075	0.924	0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.075	0.924	0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.075	0.924	0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.075	0.924	0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.075	0.924	0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.075	0.924	0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.075	0.924	0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.075	0.924	0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.075	0.924	0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.075	0.924	0.000
G82.0 Flaccid paraplegia	0.000	0.925	0.075
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere	0.000	0.925	0.075
G02.1 Meningitis in mycoses	0.000	0.925	0.075
M13.1 Monoarthritis, not elsewhere classified	0.075	0.925	0.000
E34.5 Androgen resistance syndrome	0.000	0.925	0.074
E34.4 Constitutional tall stature	0.000	0.925	0.074
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.925	0.074
E34.1 Other hypersecretion of intestinal hormones	0.000	0.925	0.074
M12.24 Villonodular synovitis (pigmented) (Hand)	0.074	0.926	0.000
G06.2 Extradural and subdural abscess, unspecified	0.000	0.926	0.074
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.926	0.074
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.926	0.074
E16.4 Abnormal secretion of gastrin	0.000	0.926	0.074
E16.3 Increased secretion of glucagon	0.000	0.926	0.074
M06.4 Inflammatory polyarthropathy	0.074	0.926	0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.073	0.926	0.000
M05.88 Other seropositive rheumatoid arthritis (Other)	0.073	0.926	0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.073	0.926	0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.073	0.926	0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.073	0.926	0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.073	0.926	0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.073	0.926	0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.073	0.926	0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.073	0.926	0.000
M13.8 Other specified arthritis	0.073	0.927	0.000
E26.9 Hyperaldosteronism, unspecified	0.000	0.927	0.073
M06.0 Seronegative rheumatoid arthritis	0.073	0.927	0.000
N42.1 Congestion and haemorrhage of prostate	0.073	0.927	0.000
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere	0.000	0.928	0.072
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere	0.000	0.928	0.072
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere	0.000	0.928	0.072
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere	0.000	0.928	0.072
D69.5 Secondary thrombocytopenia	0.000	0.928	0.072
M06.2 Rheumatoid bursitis	0.072	0.928	0.000
M06.1 Adult-onset Still's disease	0.072	0.928	0.000
G83.5 Locked-in syndrome	0.000	0.928	0.072
G83.0 Diplegia of upper limbs	0.000	0.928	0.072
M05.20 Rheumatoid vasculitis (Multiple sites)	0.072	0.928	0.000
G70 Myasthenia gravis and other myoneural disorders	0.000	0.928	0.072
M05.28 Rheumatoid vasculitis (Other)	0.071	0.928	0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.071	0.928	0.000
M05.26 Rheumatoid vasculitis (Lower leg)	0.071	0.928	0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.071	0.928	0.000
M05.24 Rheumatoid vasculitis (Hand)	0.071	0.928	0.000
M05.23 Rheumatoid vasculitis (Forearm)	0.071	0.928	0.000
M05.22 Rheumatoid vasculitis (Upper arm)	0.071	0.928	0.000
M05.21 Rheumatoid vasculitis (Shoulder region)	0.071	0.928	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.071	0.928	0.000
G73.7 Myopathy other diseases classified elsewhere	0.000	0.929	0.071
G73.6 Myopathy in metabolic diseases	0.000	0.929	0.071
G73.5 Myopathy in endocrine diseases	0.000	0.929	0.071
G73.4 Myopathy in infectious and parasitic diseases classified elsewhere	0.000	0.929	0.071
G73.3 Myasthenic syndromes in other diseases classified elsewhere	0.000	0.929	0.071
G73.2 Other myasthenic syndromes in neoplastic disease	0.000	0.929	0.071
G73.1 Eaton-Lambert syndrome	0.000	0.929	0.071
G73.0 Myasthenic syndromes in endocrine diseases	0.000	0.929	0.071
M06.30 Rheumatoid nodule (Multiple sites)	0.071	0.929	0.000
N40-N51 Diseases of male genital organs	0.071	0.929	0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.071	0.929	0.000
G12 Spinal muscular atrophy and related syndromes	0.000	0.929	0.071
G83.1 Monoplegia of lower limb	0.000	0.929	0.071
E29.9 Testicular dysfunction, unspecified	0.000	0.929	0.070

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations