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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12743802
log Bayes Factor = 12.0493
Chromosome 1   position 75,458,806  (GRCh37) Explore rs12743802 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
M45-M49 Spondylopathies
0.999 0.001 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.999 0.001 0.000
E70-E90 Metabolic disorders
0.996 0.004 0.000
M47 Spondylosis
0.995 0.005 0.000
O60-O75 Complications of labour and delivery
0.994 0.006 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.994 0.006 0.000
Chapter VI Diseases of the nervous system
0.993 0.007 0.000
Chapter IX Diseases of the circulatory system
0.992 0.008 0.000
E10-E14 Diabetes mellitus
0.987 0.013 0.000
E11 Non-insulin-dependent diabetes mellitus
0.978 0.022 0.000
M47.8 Other spondylosis
0.977 0.023 0.000
M80-M85 Disorders of bone density and structure
0.976 0.024 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.974 0.026 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.974 0.026 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.968 0.032 0.000
M47.9 Spondylosis, unspecified
0.966 0.034 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.966 0.034 0.000
E78.0 Pure hypercholesterolaemia
0.964 0.036 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.960 0.040 0.000
Chapter VII Diseases of the eye and adnexa
0.956 0.044 0.000
O70 Perineal laceration during delivery
0.951 0.049 0.000
M47.82 Other spondylosis (Cervical region)
0.948 0.052 0.000
M86-M90 Other osteopathies
0.946 0.054 0.000
O70.1 Second degree perineal laceration during delivery
0.941 0.059 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.939 0.061 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.939 0.061 0.000
M46 Other inflammatory spondylopathies
0.936 0.064 0.000
R18 Ascites
0.936 0.064 0.000
O72 Postpartum haemorrhage
0.935 0.065 0.000
I10-I15 Hypertensive diseases
0.934 0.066 0.000
E83 Disorders of mineral metabolism
0.933 0.067 0.000
M84 Disorders of continuity of bone
0.932 0.068 0.000
I60-I69 Cerebrovascular diseases
0.931 0.069 0.000
R13 Dysphagia
0.930 0.070 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.927 0.073 0.000
E00-E07 Disorders of thyroid gland
0.926 0.074 0.000
E11.5 With peripheral circulatory complications
0.925 0.075 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.922 0.078 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.920 0.080 0.000
R20 Disturbances of skin sensation
0.920 0.080 0.000
H53-H54 Visual disturbances and blindness
0.919 0.081 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.915 0.085 0.000
I80 Phlebitis and thrombophlebitis
0.912 0.088 0.000
E11.9 Without complications
0.907 0.093 0.000
R15 Faecal incontinence
0.906 0.094 0.000
I12 Hypertensive renal disease
0.905 0.095 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.905 0.095 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.904 0.096 0.000
O42 Premature rupture of membranes
0.903 0.097 0.000
E83.5 Disorders of calcium metabolism
0.902 0.098 0.000
H53 Visual disturbances
0.898 0.102 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.898 0.102 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.893 0.107 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.892 0.108 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.892 0.108 0.000
G30-G32 Other degenerative diseases of the nervous system
0.889 0.111 0.000
R22.1 Localised swelling, mass and lump, neck
0.886 0.114 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.886 0.114 0.000
R20.2 Paraesthesia of skin
0.880 0.120 0.000
I12.0 Hypertensive renal disease with renal failure
0.880 0.120 0.000
Chapter V Mental and behavioural disorders
0.875 0.125 0.000
E11.4 With neurological complications
0.873 0.127 0.000
M47.89 Other spondylosis (Site unspecified)
0.869 0.131 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.868 0.132 0.000
O72.1 Other immediate postpartum haemorrhage
0.867 0.133 0.000
G20-G26 Extrapyramidal and movement disorders
0.867 0.133 0.000
M45 Ankylosing spondylitis
0.865 0.135 0.000
Chapter II Neoplasms
0.862 0.138 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.862 0.138 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.860 0.140 0.000
I89.1 Lymphangitis
0.858 0.142 0.000
I26 Pulmonary embolism
0.854 0.146 0.000
R47-R49 Symptoms and signs involving speech and voice
0.853 0.147 0.000
H53.9 Visual disturbance, unspecified
0.853 0.147 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.852 0.148 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.850 0.150 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.850 0.150 0.000
H53.8 Other visual disturbances
0.846 0.154 0.000
O43 Placental disorders
0.845 0.155 0.000
M60-M63 Disorders of muscles
0.840 0.160 0.000
C64-C68 Malignant neoplasms of urinary tract
0.837 0.163 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.833 0.167 0.000
M84.0 Malunion of fracture
0.832 0.167 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.832 0.168 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.831 0.169 0.000
I89.0 Lymphoedema, not elsewhere classified
0.831 0.169 0.000
E87.5 Hyperkalaemia
0.830 0.170 0.000
R40 Somnolence, stupor and coma
0.830 0.170 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.825 0.175 0.000
M40-M43 Deforming dorsopathies
0.822 0.178 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.819 0.181 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.819 0.181 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.818 0.182 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.817 0.183 0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.816 0.184 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.813 0.187 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.809 0.191 0.000
G62 Other polyneuropathies
0.809 0.191 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.808 0.192 0.000
I86 Varicose veins of other sites
0.807 0.193 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.805 0.195 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.805 0.195 0.000
E04 Other non-toxic goitre
0.802 0.198 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.801 0.199 0.000
O44 Placenta praevia
0.800 0.200 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.799 0.200 0.000
R40.2 Coma, unspecified
0.799 0.201 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.799 0.201 0.000
O80-O84 Delivery
0.799 0.201 0.000
G25 Other extrapyramidal and movement disorders
0.798 0.202 0.000
M85 Other disorders of bone density and structure
0.795 0.205 0.000
E11.2 With renal complications
0.794 0.206 0.000
E20-E35 Disorders of other endocrine glands
0.793 0.207 0.000
I81 Portal vein thrombosis
0.793 0.207 0.000
I61 Intracerebral haemorrhage
0.792 0.208 0.000
O34.3 Maternal care for cervical incompetence
0.791 0.209 0.000
Q50-Q56 Congenital malformations of genital organs
0.790 0.210 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.790 0.210 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.787 0.213 0.000
H43-H45 Disorders of vitreous body and globe
0.786 0.214 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.786 0.214 0.000
R47 Speech disturbances, not elsewhere classified
0.784 0.216 0.000
H55-H59 Other disorders of eye and adnexa
0.784 0.216 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.783 0.217 0.000
O33 Maternal care for known or suspected disproportion
0.783 0.217 0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)
0.782 0.218 0.000
O34.1 Maternal care for tumour of corpus uteri
0.781 0.219 0.000
M20-M25 Other joint disorders
0.780 0.220 0.000
E83.4 Disorders of magnesium metabolism
0.779 0.221 0.000
M89 Other disorders of bone
0.779 0.221 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.776 0.224 0.000
H53.2 Diplopia
0.774 0.226 0.000
O72.0 Third-stage haemorrhage
0.772 0.227 0.000
M86 Osteomyelitis
0.771 0.229 0.000
M87 Osteonecrosis
0.771 0.229 0.000
G70-G73 Diseases of myoneural junction and muscle
0.771 0.229 0.000
O20 Haemorrhage in early pregnancy
0.771 0.229 0.000
O24 Diabetes mellitus in pregnancy
0.769 0.231 0.000
M90 Osteopathies in diseases classified elsewhere
0.769 0.231 0.000
O34.4 Maternal care for other abnormalities of cervix
0.769 0.231 0.000
I63 Cerebral infarction
0.768 0.232 0.000
C67 Malignant neoplasm of bladder
0.768 0.232 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.767 0.233 0.000
O85-O92 Complications predominantly related to the puerperium
0.766 0.234 0.000
H10-H13 Disorders of conjunctiva
0.764 0.236 0.000
E73 Lactose intolerance
0.764 0.236 0.000
O66 Other obstructed labour
0.761 0.239 0.000
E78.8 Other disorders of lipoprotein metabolism
0.761 0.239 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.760 0.240 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.760 0.240 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.759 0.241 0.000
M81 Osteoporosis without pathological fracture
0.758 0.242 0.000
I88 Nonspecific lymphadenitis
0.757 0.242 0.000
G82 Paraplegia and tetraplegia
0.757 0.243 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.757 0.243 0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.755 0.245 0.000
R30-R39 Symptoms and signs involving the urinary system
0.753 0.247 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.752 0.248 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.750 0.250 0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage
0.748 0.251 0.000
O43.1 Malformation of placenta
0.748 0.252 0.000
E40-E46 Malnutrition
0.748 0.252 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.746 0.254 0.000
O70.9 Perineal laceration during delivery, unspecified
0.743 0.256 0.000
O42.9 Premature rupture of membranes, unspecified
0.743 0.257 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.743 0.257 0.000
R47.8 Other and unspecified speech disturbances
0.742 0.258 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.742 0.258 0.000
E11.0 With coma
0.742 0.258 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.740 0.260 0.000
E10 Insulin-dependent diabetes mellitus
0.740 0.260 0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified
0.740 0.260 0.000
E05.9 Thyrotoxicosis, unspecified
0.740 0.260 0.000
M82 Osteoporosis in diseases classified elsewhere
0.739 0.261 0.000
I85 Oesophageal varices
0.739 0.261 0.000
F30-F39 Mood [affective] disorders
0.739 0.261 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.738 0.262 0.000
R22.2 Localised swelling, mass and lump, trunk
0.735 0.265 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.733 0.267 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.731 0.268 0.000
M80 Osteoporosis with pathological fracture
0.731 0.269 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.731 0.269 0.000
E86 Volume depletion
0.731 0.269 0.000
G90-G99 Other disorders of the nervous system
0.731 0.269 0.000
G03 Meningitis due to other and unspecified causes
0.731 0.269 0.000
C44 Other malignant neoplasms of skin
0.729 0.271 0.000
M88 Paget's disease of bone [osteitis deformans]
0.728 0.272 0.000
E07 Other disorders of thyroid
0.728 0.272 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.728 0.272 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.728 0.272 0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)
0.726 0.273 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.726 0.274 0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)
0.726 0.274 0.000
M62 Other disorders of muscle
0.725 0.275 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.723 0.277 0.000
E04.2 Non-toxic multinodular goitre
0.723 0.277 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.723 0.277 0.000
I62 Other nontraumatic intracranial haemorrhage
0.722 0.278 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.722 0.278 0.000
O47 False labour
0.720 0.280 0.000
Chapter I Certain infectious and parasitic diseases
0.719 0.281 0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.719 0.281 0.000
M00-M03 Infectious arthropathies
0.718 0.282 0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes
0.717 0.283 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C43 Malignant melanoma of skin
0.717 0.283 0.000
M49 Spondylopathies in diseases classified elsewhere
0.716 0.284 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.284 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.715 0.285 0.000
E85 Amyloidosis
0.714 0.286 0.000
E84 Cystic fibrosis
0.714 0.286 0.000
E79 Disorders of purine and pyrimidine metabolism
0.714 0.286 0.000
E77 Disorders of glycoprotein metabolism
0.714 0.286 0.000
E76 Disorders of glycosaminoglycan metabolism
0.714 0.286 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.714 0.286 0.000
E74 Other disorders of carbohydrate metabolism
0.714 0.286 0.000
E72 Other disorders of amino-acid metabolism
0.714 0.286 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.714 0.286 0.000
E70 Disorders of aromatic amino-acid metabolism
0.714 0.286 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.714 0.286 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.714 0.286 0.000
F80-F89 Disorders of psychological development
0.714 0.286 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.714 0.286 0.000
Q80-Q89 Other congenital malformations
0.713 0.287 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.713 0.287 0.000
O74 Complications of anaesthesia during labour and delivery
0.713 0.287 0.000
O71 Other obstetric trauma
0.713 0.287 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.713 0.287 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.713 0.287 0.000
O61 Failed induction of labour
0.713 0.287 0.000
O60 Preterm delivery
0.713 0.287 0.000
O45 Premature separation of placenta [abruptio placentae]
0.713 0.287 0.000
O31 Complications specific to multiple gestation
0.713 0.287 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.712 0.287 0.000
M84.4 Pathological fracture, not elsewhere classified
0.712 0.288 0.000
I00-I02 Acute rheumatic fever
0.711 0.288 0.000
E87.7 Fluid overload
0.711 0.289 0.000
G63.2 Diabetic polyneuropathy
0.708 0.292 0.000
E12 Malnutrition-related diabetes mellitus
0.708 0.292 0.000
R32 Unspecified urinary incontinence
0.707 0.293 0.000
G80 Infantile cerebral palsy
0.707 0.293 0.000
O73 Retained placenta and membranes, without haemorrhage
0.707 0.293 0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)
0.706 0.294 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.706 0.294 0.000
M84.03 Malunion of fracture (Forearm)
0.706 0.294 0.000
O21 Excessive vomiting in pregnancy
0.705 0.294 0.000
G30 Alzheimer's disease
0.705 0.295 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.704 0.296 0.000
E11.6 With other specified complications
0.702 0.298 0.000
E11.8 With unspecified complications
0.701 0.299 0.000
E11.7 With multiple complications
0.701 0.299 0.000
E11.1 With ketoacidosis
0.701 0.299 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.701 0.299 0.000
I12.9 Hypertensive renal disease without renal failure
0.701 0.299 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.701 0.299 0.000
M47.84 Other spondylosis (Thoracic region)
0.701 0.299 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.701 0.299 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.701 0.299 0.000
O28 Abnormal findings on antenatal screening of mother
0.700 0.300 0.000
M83 Adult osteomalacia
0.700 0.300 0.000
M84.07 Malunion of fracture (Ankle and foot)
0.700 0.300 0.000
R22.3 Localised swelling, mass and lump, upper limb
0.699 0.300 0.000
R35 Polyuria
0.699 0.301 0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified
0.698 0.302 0.000
O34.8 Maternal care for other abnormalities of pelvic organs
0.698 0.302 0.000
O34.6 Maternal care for abnormality of vagina
0.698 0.302 0.000
O34.5 Maternal care for other abnormalities of gravid uterus
0.698 0.302 0.000
O34.0 Maternal care for congenital malformation of uterus
0.698 0.302 0.000
O75.0 Maternal distress during labour and delivery
0.697 0.303 0.000
I11 Hypertensive heart disease
0.697 0.303 0.000
M91-M94 Chondropathies
0.696 0.304 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.696 0.304 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.695 0.304 0.000
M47.1 Other spondylosis with myelopathy
0.695 0.305 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.695 0.305 0.000
E13 Other specified diabetes mellitus
0.695 0.305 0.000
F05.9 Delirium, unspecified
0.694 0.306 0.000
G61 Inflammatory polyneuropathy
0.694 0.306 0.000
G25.0 Essential tremor
0.694 0.306 0.000
E78.6 Lipoprotein deficiency
0.694 0.306 0.000
E78.4 Other hyperlipidaemia
0.694 0.306 0.000
E78.3 Hyperchylomicronaemia
0.694 0.306 0.000
E78.1 Pure hyperglyceridaemia
0.694 0.306 0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)
0.693 0.307 0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)
0.693 0.307 0.000
M47.94 Spondylosis, unspecified (Thoracic region)
0.693 0.307 0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)
0.693 0.307 0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)
0.693 0.307 0.000
G81 Hemiplegia
0.693 0.307 0.000
G62.9 Polyneuropathy, unspecified
0.692 0.308 0.000
E14 Unspecified diabetes mellitus
0.691 0.309 0.000
R50-R69 General symptoms and signs
0.689 0.311 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.688 0.312 0.000
O62 Abnormalities of forces of labour
0.687 0.313 0.000
M34 Systemic sclerosis
0.686 0.314 0.000
Q00-Q07 Congenital malformations of the nervous system
0.685 0.314 0.000
H40-H42 Glaucoma
0.685 0.315 0.000
I82 Other venous embolism and thrombosis
0.684 0.316 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.684 0.316 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.684 0.316 0.000
E04.9 Non-toxic goitre, unspecified
0.683 0.317 0.000
O70.3 Fourth degree perineal laceration during delivery
0.682 0.318 0.000
R16.0 Hepatomegaly, not elsewhere classified
0.681 0.319 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.681 0.319 0.000
G60 Hereditary and idiopathic neuropathy
0.681 0.319 0.000
O23 Infections of genito-urinary tract in pregnancy
0.680 0.320 0.000
H55 Nystagmus and other irregular eye movements
0.680 0.320 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.680 0.320 0.000
R22.9 Localised swelling, mass and lump, unspecified
0.679 0.321 0.000
G24 Dystonia
0.679 0.321 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.678 0.322 0.000
I69 Sequelae of cerebrovascular disease
0.678 0.322 0.000
M89.0 Algoneurodystrophy
0.677 0.323 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.677 0.323 0.000
I15 Secondary hypertension
0.676 0.324 0.000
H25-H28 Disorders of lens
0.676 0.324 0.000
E03 Other hypothyroidism
0.675 0.325 0.000
O29 Complications of anaesthesia during pregnancy
0.673 0.326 0.000
O22 Venous complications in pregnancy
0.673 0.326 0.000
O25 Malnutrition in pregnancy
0.673 0.326 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.674 0.326 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.674 0.326 0.000
M43 Other deforming dorsopathies
0.672 0.328 0.000
M46.8 Other specified inflammatory spondylopathies
0.671 0.328 0.000
M46.5 Other infective spondylopathies
0.671 0.328 0.000
M46.4 Discitis, unspecified
0.671 0.328 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.671 0.328 0.000
M46.2 Osteomyelitis of vertebra
0.671 0.328 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.671 0.328 0.000
M46.0 Spinal enthesopathy
0.671 0.328 0.000
O72.3 Postpartum coagulation defects
0.670 0.329 0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)
0.670 0.330 0.000
I13 Hypertensive heart and renal disease
0.669 0.330 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.669 0.331 0.000
E83.8 Other disorders of mineral metabolism
0.669 0.331 0.000
E83.2 Disorders of zinc metabolism
0.669 0.331 0.000
E83.0 Disorders of copper metabolism
0.669 0.331 0.000
M84.9 Disorder of continuity of bone, unspecified
0.668 0.332 0.000
M84.8 Other disorders of continuity of bone
0.668 0.332 0.000
M84.3 Stress fracture, not elsewhere classified
0.668 0.332 0.000
M84.2 Delayed union of fracture
0.668 0.332 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.667 0.332 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.667 0.332 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.667 0.333 0.000
R25 Abnormal involuntary movements
0.666 0.334 0.000
M85.8 Other specified disorders of bone density and structure
0.665 0.334 0.000
G64 Other disorders of peripheral nervous system
0.664 0.335 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.664 0.336 0.000
E00 Congenital iodine-deficiency syndrome
0.664 0.336 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.664 0.336 0.000
O41 Other disorders of amniotic fluid and membranes
0.663 0.337 0.000
G83 Other paralytic syndromes
0.660 0.340 0.000
R22.7 Localised swelling, mass and lump, multiple sites
0.660 0.340 0.000
E89.2 Postprocedural hypoparathyroidism
0.660 0.340 0.000
R20.3 Hyperaesthesia
0.659 0.341 0.000
R20.1 Hypoaesthesia of skin
0.659 0.341 0.000
R20.0 Anaesthesia of skin
0.659 0.341 0.000
H10 Conjunctivitis
0.659 0.341 0.000
O30 Multiple gestation
0.659 0.341 0.000
O80 Single spontaneous delivery
0.658 0.342 0.000
M48 Other spondylopathies
0.657 0.343 0.000
B25-B34 Other viral diseases
0.657 0.343 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.656 0.344 0.000
Q35-Q37 Cleft lip and cleft palate
0.656 0.344 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.656 0.344 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.656 0.344 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.655 0.344 0.000
M24 Other specific joint derangements
0.655 0.345 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.655 0.345 0.000
O36 Maternal care for other known or suspected foetal problems
0.655 0.345 0.000
R11 Nausea and vomiting
0.654 0.346 0.000
G31.8 Other specified degenerative diseases of nervous system
0.654 0.346 0.000
Chapter XXII Codes for special purposes
0.653 0.346 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.653 0.347 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.652 0.348 0.000
R41.0 Disorientation, unspecified
0.651 0.349 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.651 0.349 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.651 0.349 0.000
R46 Symptoms and signs involving appearance and behaviour
0.650 0.349 0.000
G82.2 Paraplegia, unspecified
0.650 0.350 0.000
E87.0 Hyperosmolality and hypernatraemia
0.649 0.351 0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.649 0.351 0.000
I61.8 Other intracerebral haemorrhage
0.649 0.351 0.000
I28 Other diseases of pulmonary vessels
0.648 0.352 0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent
0.647 0.352 0.000
O42.2 Premature rupture of membranes, labour delayed by therapy
0.647 0.353 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.647 0.353 0.000
M86.9 Osteomyelitis, unspecified
0.646 0.354 0.000
M87.9 Osteonecrosis, unspecified
0.646 0.354 0.000
C65 Malignant neoplasm of renal pelvis
0.646 0.354 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.645 0.355 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.645 0.355 0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus
0.645 0.355 0.000
H53.6 Night blindness
0.644 0.356 0.000
H53.5 Colour vision deficiencies
0.644 0.356 0.000
H53.3 Other disorders of binocular vision
0.644 0.356 0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress
0.644 0.356 0.000
M62.8 Other specified disorders of muscle
0.643 0.357 0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)
0.643 0.357 0.000
O40 Polyhydramnios
0.643 0.357 0.000
H44 Disorders of globe
0.643 0.357 0.000
G62.8 Other specified polyneuropathies
0.643 0.357 0.000
M90.7 Fracture of bone in neoplastic disease
0.642 0.357 0.000
O26.8 Other specified pregnancy-related conditions
0.642 0.357 0.000
G51 Facial nerve disorders
0.642 0.358 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.641 0.358 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.640 0.360 0.000
E50-E64 Other nutritional deficiencies
0.640 0.360 0.000
C67.9 Bladder, unspecified
0.640 0.360 0.000
I87 Other disorders of veins
0.640 0.360 0.000
R43 Disturbances of smell and taste
0.639 0.361 0.000
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)
0.639 0.361 0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)
0.639 0.361 0.000
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)
0.639 0.361 0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)
0.639 0.361 0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)
0.639 0.361 0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)
0.639 0.361 0.000
F00 Dementia in Alzheimer's disease
0.639 0.361 0.000
R55 Syncope and collapse
0.639 0.361 0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)
0.638 0.362 0.000
C44.1 Skin of eyelid, including canthus
0.638 0.362 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.637 0.362 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.637 0.363 0.000
F60-F69 Disorders of adult personality and behaviour
0.637 0.363 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.637 0.363 0.000
G03.9 Meningitis, unspecified
0.637 0.363 0.000
O75.2 Pyrexia during labour, not elsewhere classified
0.636 0.364 0.000
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures
0.635 0.364 0.000
O35.6 Maternal care for (suspected) damage to foetus by radiation
0.635 0.364 0.000
O35.5 Maternal care for (suspected) damage to foetus by drugs
0.635 0.364 0.000
O35.4 Maternal care for (suspected) damage to foetus from alcohol
0.635 0.364 0.000
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother
0.635 0.364 0.000
O35.2 Maternal care for (suspected) hereditary disease in foetus
0.635 0.364 0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus
0.635 0.364 0.000
R16.1 Splenomegaly, not elsewhere classified
0.635 0.365 0.000
I86.4 Gastric varices
0.635 0.365 0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
0.634 0.366 0.000
H46 Optic neuritis
0.634 0.366 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.634 0.366 0.000
C67.1 Dome of bladder
0.634 0.366 0.000
M65-M68 Disorders of synovium and tendon
0.632 0.368 0.000
I65.2 Occlusion and stenosis of carotid artery
0.632 0.368 0.000
O33.9 Maternal care for disproportion, unspecified
0.632 0.368 0.000
M31 Other necrotising vasculopathies
0.632 0.368 0.000
E24 Cushing's syndrome
0.630 0.369 0.000
R41.2 Retrograde amnesia
0.630 0.370 0.000
F33 Recurrent depressive disorder
0.630 0.370 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.629 0.371 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.629 0.371 0.000
R77 Other abnormalities of plasma proteins
0.629 0.371 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.628 0.371 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.627 0.373 0.000
F70-F79 Mental retardation
0.627 0.373 0.000
C44.4 Skin of scalp and neck
0.626 0.374 0.000
O44.1 Placenta praevia with haemorrhage
0.626 0.374 0.000
I86.1 Scrotal varices
0.626 0.374 0.000
O26.2 Pregnancy care of habitual aborter
0.625 0.375 0.000
M21 Other acquired deformities of limbs
0.625 0.375 0.000
M41 Scoliosis
0.624 0.376 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.623 0.377 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.623 0.377 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.622 0.378 0.000
E87.4 Mixed disorder of acid-base balance
0.622 0.378 0.000
C43.9 Malignant melanoma of skin, unspecified
0.622 0.378 0.000
G23 Other degenerative diseases of basal ganglia
0.621 0.379 0.000
G21 Secondary Parkinsonism
0.621 0.379 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.621 0.379 0.000
G22 Parkinsonism in diseases classified elsewhere
0.621 0.379 0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere
0.621 0.379 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.620 0.379 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.620 0.379 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.620 0.379 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.620 0.379 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.620 0.379 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.620 0.379 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.620 0.379 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.620 0.379 0.000
E20 Hypoparathyroidism
0.619 0.381 0.000
O44.0 Placenta praevia specified as without haemorrhage
0.618 0.382 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.618 0.382 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.618 0.382 0.000
O26.9 Pregnancy-related condition, unspecified
0.618 0.382 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.618 0.382 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.618 0.382 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.618 0.382 0.000
G00 Bacterial meningitis, not elsewhere classified
0.618 0.382 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.618 0.382 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.618 0.382 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.618 0.382 0.000
C51-C58 Malignant neoplasms of female genital organs
0.618 0.382 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.618 0.382 0.000
O75.9 Complication of labour and delivery, unspecified
0.617 0.383 0.000
O75.8 Other specified complications of labour and delivery
0.617 0.383 0.000
O75.5 Delayed delivery after artificial rupture of membranes
0.617 0.383 0.000
O75.4 Other complications of obstetric surgery and procedures
0.617 0.383 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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