TreeWAS – Variant ID: rs12761761

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T36-T50 Poisoning by drugs, medicaments and biological substances	0.991	0.009	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.983	0.017	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.980	0.020	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.975	0.025	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.972	0.028	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.965	0.035	0.000
T43.2 Other and unspecified antidepressants	0.898	0.102	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.895	0.105	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.894	0.106	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.881	0.119	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.872	0.128	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.853	0.147	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.851	0.149	0.000
T40.6 Other and unspecified narcotics	0.844	0.156	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.817	0.183	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.812	0.188	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.805	0.195	0.000
T39.0 Salicylates	0.792	0.208	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.790	0.210	0.000
T39.1 4-Aminophenol derivatives	0.782	0.218	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.775	0.225	0.000
T45.5 Anticoagulants	0.772	0.228	0.000
T38.1 Thyroid hormones and substitutes	0.758	0.242	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.755	0.245	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.749	0.251	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.747	0.253	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.726	0.274	0.000
T45.0 Antiallergic and antiemetic drugs	0.713	0.287	0.000
T43.6 Psychostimulants with abuse potential	0.711	0.289	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.711	0.289	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.710	0.289	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.710	0.289	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.705	0.295	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.705	0.295	0.000
T42.3 Barbiturates	0.705	0.295	0.000
T42.2 Succinimides and oxazolidinediones	0.705	0.295	0.000
T39.4 Antirheumatics, not elsewhere classified	0.703	0.297	0.000
T39.2 Pyrazolone derivatives	0.703	0.297	0.000
T43.9 Psychotropic drug, unspecified	0.697	0.303	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.697	0.303	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.689	0.311	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.686	0.313	0.000
T36 Poisoning by systemic antibiotics	0.680	0.320	0.000
T42.4 Benzodiazepines	0.674	0.326	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.656	0.343	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.655	0.345	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.654	0.346	0.000
T47.2 Stimulant laxatives	0.642	0.358	0.000
T38.9 Other and unspecified hormone antagonists	0.642	0.358	0.000
T38.7 Androgens and anabolic congeners	0.642	0.358	0.000
T38.5 Other oestrogens and progestogens	0.642	0.358	0.000
T38.4 Oral contraceptives	0.642	0.358	0.000
T38.2 Antithyroid drugs	0.642	0.358	0.000
T38.0 Glucocorticoids and synthetic analogues	0.642	0.358	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.632	0.368	0.000
T40.8 Lysergide [LSD]	0.632	0.368	0.000
T40.7 Cannabis (derivatives)	0.632	0.368	0.000
T40.5 Cocaine	0.632	0.368	0.000
T40.3 Methadone	0.632	0.368	0.000
T40.1 Heroin	0.632	0.368	0.000
T40.0 Opium	0.632	0.368	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.628	0.372	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.625	0.375	0.000
T45.8 Other primarily systemic and haematological agents	0.625	0.375	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.625	0.375	0.000
T45.6 Fibrinolysis-affecting drugs	0.625	0.375	0.000
T45.4 Iron and its compounds	0.625	0.375	0.000
T45.3 Enzymes, not elsewhere classified	0.625	0.375	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.620	0.380	0.000
T42.1 Iminostilbenes	0.615	0.384	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.610	0.389	0.000
T37.5 Antiviral drugs	0.610	0.389	0.000
T37.4 Anthelminthics	0.610	0.389	0.000
T37.3 Other antiprotozoal drugs	0.610	0.389	0.000
T37.1 Antimycobacterial drugs	0.610	0.389	0.000
T37.0 Sulphonamides	0.610	0.389	0.000
T45.2 Vitamins, not elsewhere classified	0.605	0.395	0.000
T47.4 Other laxatives	0.602	0.397	0.000
T40.2 Other opioids	0.602	0.398	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.577	0.423	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.577	0.423	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.577	0.423	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.577	0.423	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.577	0.423	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.577	0.423	0.000
T44.0 Anticholinesterase agents	0.577	0.423	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.571	0.429	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.567	0.433	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.566	0.434	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.566	0.434	0.000
T47.7 Emetics	0.566	0.434	0.000
T47.6 Antidiarrhoeal drugs	0.566	0.434	0.000
T47.5 Digestants	0.566	0.434	0.000
T47.3 Saline and osmotic laxatives	0.566	0.434	0.000
T47.0 Histamine H(2)-receptor antagonists	0.566	0.434	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.560	0.440	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.556	0.444	0.000
T48.5 Anti-common-cold drugs	0.556	0.444	0.000
T48.4 Expectorants	0.556	0.444	0.000
T48.3 Antitussives	0.556	0.444	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.556	0.444	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.556	0.444	0.000
T48.0 Oxytocic drugs	0.556	0.444	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.547	0.452	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.545	0.455	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.529	0.471	0.000
T36.4 Tetracyclines	0.528	0.472	0.000
T42.0 Hydantoin derivatives	0.513	0.486	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.511	0.489	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.510	0.490	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.510	0.490	0.000
T46.7 Peripheral vasodilators	0.510	0.490	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.510	0.490	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.510	0.490	0.000
T41.5 Therapeutic gases	0.509	0.490	0.000
T41.4 Anaesthetic, unspecified	0.509	0.490	0.000
T41.3 Local anaesthetics	0.509	0.490	0.000
T41.2 Other and unspecified general anaesthetics	0.509	0.490	0.000
T41.1 Intravenous anaesthetics	0.509	0.490	0.000
T41.0 Inhaled anaesthetics	0.509	0.490	0.000
T49.9 Topical agent, unspecified	0.509	0.490	0.000
T49.8 Other topical agents	0.509	0.490	0.000
T49.7 Dental drugs, topically applied	0.509	0.490	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.509	0.490	0.000
T49.5 Ophthalmological drugs and preparations	0.509	0.490	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.509	0.490	0.000
T49.3 Emollients, demulcents and protectants	0.509	0.490	0.000
T49.2 Local astringents and local detergents	0.509	0.490	0.000
T49.1 Antipruritics	0.509	0.490	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.509	0.490	0.000
T36.9 Systemic antibiotic, unspecified	0.487	0.512	0.000
T36.8 Other systemic antibiotics	0.487	0.512	0.000
T36.7 Antifungal antibiotics, systemically used	0.487	0.512	0.000
T36.6 Rifamycins	0.487	0.512	0.000
T36.5 Aminoglycosides	0.487	0.512	0.000
T36.3 Macrolides	0.487	0.512	0.000
T36.2 Chloramphenicol group	0.487	0.512	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.487	0.512	0.000
T46.1 Calcium-channel blockers	0.469	0.531	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.465	0.535	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.449	0.551	0.000
T40.4 Other synthetic narcotics	0.416	0.583	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.410	0.589	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.401	0.598	0.000
T50.4 Drugs affecting uric acid metabolism	0.401	0.599	0.000
T36.0 Penicillins	0.397	0.603	0.000
T50.7 Analeptics and opioid receptor antagonists	0.393	0.607	0.000
T50.5 Appetite depressants	0.393	0.607	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.393	0.607	0.000
T50.1 Loop [high-ceiling] diuretics	0.393	0.607	0.000
T50.0 Mineralocorticoids and their antagonists	0.393	0.607	0.000
T50.8 Diagnostic agents	0.382	0.618	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.171	0.829	0.000
I34.1 Mitral (valve) prolapse	0.036	0.964	0.000
T78.4 Allergy, unspecified	0.000	0.974	0.026
C56 Malignant neoplasm of ovary	0.000	0.979	0.021
T78 Adverse effects, not elsewhere classified	0.000	0.985	0.015
I34 Nonrheumatic mitral valve disorders	0.013	0.987	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.000	0.988	0.012
Q43 Other congenital malformations of intestine	0.012	0.988	0.000
Q43.8 Other specified congenital malformations of intestine	0.012	0.988	0.000
T78.3 Angioneurotic oedema	0.000	0.988	0.012
D37.4 Colon	0.012	0.988	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.000	0.989	0.011
Q38-Q45 Other congenital malformations of the digestive system	0.011	0.989	0.000
T78.9 Adverse effect, unspecified	0.000	0.989	0.011
T78.8 Other adverse effects, not elsewhere classified	0.000	0.989	0.011
Q38 Other congenital malformations of tongue, mouth and pharynx	0.010	0.990	0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.000	0.990	0.010
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.010	0.990	0.000
Q43.1 Hirschsprung's disease	0.010	0.990	0.000
Q43.3 Congenital malformations of intestinal fixation	0.010	0.990	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.009	0.990	0.000
Q43.0 Meckel's diverticulum	0.009	0.990	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.009	0.991	0.000
Q38.7 Pharyngeal pouch	0.009	0.991	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.009	0.991	0.000
Q43.7 Persistent cloaca	0.009	0.991	0.000
Q43.6 Congenital fistula of rectum and anus	0.009	0.991	0.000
Q43.5 Ectopic anus	0.009	0.991	0.000
Q43.4 Duplication of intestine	0.009	0.991	0.000
Q43.2 Other congenital functional disorders of colon	0.009	0.991	0.000
Q38.8 Other congenital malformations of pharynx	0.009	0.991	0.000
Q45 Other congenital malformations of digestive system	0.009	0.991	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.991	0.009
Q40 Other congenital malformations of upper alimentary tract	0.008	0.992	0.000
Q38.6 Other congenital malformations of mouth	0.008	0.992	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.008	0.992	0.000
Q60-Q64 Congenital malformations of the urinary system	0.008	0.992	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.008	0.992	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.008	0.992	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.008	0.992	0.000
I34.0 Mitral (valve) insufficiency	0.008	0.992	0.000
Q63 Other congenital malformations of kidney	0.008	0.992	0.000
M06.9 Rheumatoid arthritis, unspecified	0.000	0.992	0.008
Q60 Renal agenesis and other reduction defects of kidney	0.008	0.992	0.000
Q38.5 Congenital malformations of palate, not elsewhere classified	0.008	0.992	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.008	0.992	0.000
Q38.3 Other congenital malformations of tongue	0.008	0.992	0.000
Q38.2 Macroglossia	0.008	0.992	0.000
Q38.1 Ankyloglossia	0.008	0.992	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.008	0.992	0.000
Q63.0 Accessory kidney	0.008	0.992	0.000
Q39 Congenital malformations of oesophagus	0.008	0.992	0.000
D37.6 Liver, gallbladder and bile ducts	0.008	0.992	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.992	0.008
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.993	0.007
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.007	0.993	0.000
T78.2 Anaphylactic shock, unspecified	0.000	0.993	0.007
Q00-Q07 Congenital malformations of the nervous system	0.007	0.993	0.000
D37.9 Digestive organ, unspecified	0.007	0.993	0.000
Q60.2 Renal agenesis, unspecified	0.007	0.993	0.000
Q45.8 Other specified congenital malformations of digestive system	0.007	0.993	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.007	0.993	0.000
D37.3 Appendix	0.007	0.993	0.000
Q60.0 Renal agenesis, unilateral	0.007	0.993	0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.000	0.993	0.007
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.993	0.007
D37.2 Small intestine	0.007	0.993	0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.007	0.993	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.007	0.993	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.007	0.993	0.000
Q64 Other congenital malformations of urinary system	0.007	0.993	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.993	0.007
Q05 Spina bifida	0.007	0.993	0.000
Q45.9 Congenital malformation of digestive system, unspecified	0.006	0.993	0.000
Q45.2 Congenital pancreatic cyst	0.006	0.993	0.000
Q45.1 Annular pancreas	0.006	0.993	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.006	0.993	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.006	0.993	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.993	0.007
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.006	0.993	0.000
D37.0 Lip, oral cavity and pharynx	0.006	0.993	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.006	0.994	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.006	0.994	0.000
D37.7 Other digestive organs	0.006	0.994	0.000
T66-T78 Other and unspecified effects of external causes	0.001	0.994	0.006
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.006	0.994	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.006	0.994	0.000
Q40.2 Other specified congenital malformations of stomach	0.006	0.994	0.000
Q40.1 Congenital hiatus hernia	0.006	0.994	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.006	0.994	0.000
Q05.9 Spina bifida, unspecified	0.006	0.994	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.994	0.006
Q24 Other congenital malformations of heart	0.006	0.994	0.000
Q41.9 Congenital absence, atresia and stenosis of small intestine, part unspecified	0.006	0.994	0.000
Q41.8 Congenital absence, atresia and stenosis of other specified parts of small intestine	0.006	0.994	0.000
Q41.2 Congenital absence, atresia and stenosis of ileum	0.006	0.994	0.000
Q41.1 Congenital absence, atresia and stenosis of jejunum	0.006	0.994	0.000
Q41.0 Congenital absence, atresia and stenosis of duodenum	0.006	0.994	0.000
Q42.9 Congenital absence, atresia and stenosis of large intestine, part unspecified	0.006	0.994	0.000
Q42.8 Congenital absence, atresia and stenosis of other parts of large intestine	0.006	0.994	0.000
Q42.3 Congenital absence, atresia and stenosis of anus without fistula	0.006	0.994	0.000
Q42.2 Congenital absence, atresia and stenosis of anus with fistula	0.006	0.994	0.000
Q42.1 Congenital absence, atresia and stenosis of rectum without fistula	0.006	0.994	0.000
Q42.0 Congenital absence, atresia and stenosis of rectum with fistula	0.006	0.994	0.000
Q35-Q37 Cleft lip and cleft palate	0.006	0.994	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.006	0.994	0.000
Q63.8 Other specified congenital malformations of kidney	0.006	0.994	0.000
Q63.3 Hyperplastic and giant kidney	0.006	0.994	0.000
Q60.6 Potter's syndrome	0.006	0.994	0.000
Q60.5 Renal hypoplasia, unspecified	0.006	0.994	0.000
Q60.4 Renal hypoplasia, bilateral	0.006	0.994	0.000
Q60.3 Renal hypoplasia, unilateral	0.006	0.994	0.000
Q60.1 Renal agenesis, bilateral	0.006	0.994	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.006	0.994	0.000
Q25 Congenital malformations of great arteries	0.006	0.994	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.006	0.994	0.000
D37.1 Stomach	0.006	0.994	0.000
Q39.9 Congenital malformation of oesophagus, unspecified	0.006	0.994	0.000
Q39.8 Other congenital malformations of oesophagus	0.006	0.994	0.000
Q39.5 Congenital dilatation of oesophagus	0.006	0.994	0.000
Q39.3 Congenital stenosis and stricture of oesophagus	0.006	0.994	0.000
Q39.2 Congenital tracheooesophageal fistula without atresia	0.006	0.994	0.000
Q39.1 Atresia of oesophagus with tracheooesophageal fistula	0.006	0.994	0.000
Q39.0 Atresia of oesophagus without fistula	0.006	0.994	0.000
Q21 Congenital malformations of cardiac septa	0.006	0.994	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.006	0.994	0.000
Q39.6 Diverticulum of oesophagus	0.005	0.994	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.006	0.994	0.000
S90 Superficial injury of ankle and foot	0.006	0.994	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.006	0.994	0.000
Q90 Down's syndrome	0.005	0.994	0.000
Q79.6 Ehlers-Danlos syndrome	0.005	0.994	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.005	0.994	0.000
Q44.7 Other congenital malformations of liver	0.005	0.995	0.000
Q44.5 Other congenital malformations of bile ducts	0.005	0.995	0.000
Q44.4 Choledochal cyst	0.005	0.995	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.005	0.995	0.000
Q44.2 Atresia of bile ducts	0.005	0.995	0.000
Q44.1 Other congenital malformations of gallbladder	0.005	0.995	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.005	0.995	0.000
Q06 Other congenital malformations of spinal cord	0.005	0.995	0.000
Q04 Other congenital malformations of brain	0.005	0.995	0.000
Q03 Congenital hydrocephalus	0.005	0.995	0.000
Q01 Encephalocele	0.005	0.995	0.000
Q00 Anencephaly and similar malformations	0.005	0.995	0.000
Q02 Microcephaly	0.005	0.995	0.000
Q39.4 Oesophageal web	0.005	0.995	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.005	0.995	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.005	0.995	0.000
Q96 Turner's syndrome	0.005	0.995	0.000
Q05.4 Unspecified spina bifida with hydrocephalus	0.005	0.995	0.000
Q62.5 Duplication of ureter	0.005	0.995	0.000
S90.3 Contusion of other and unspecified parts of foot	0.005	0.995	0.000
Q24.8 Other specified congenital malformations of heart	0.005	0.995	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.005	0.995	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.005	0.995	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.005	0.995	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.005	0.995	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.005	0.995	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.005	0.995	0.000
Q24.0 Dextrocardia	0.005	0.995	0.000
Q26 Congenital malformations of great veins	0.005	0.995	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.005	0.995	0.000
T70 Effects of air pressure and water pressure	0.001	0.995	0.005
Q25.0 Patent ductus arteriosus	0.005	0.995	0.000
Q78 Other osteochondrodysplasias	0.005	0.995	0.000
Q64.9 Congenital malformation of urinary system, unspecified	0.005	0.995	0.000
Q64.8 Other specified congenital malformations of urinary system	0.005	0.995	0.000
Q64.6 Congenital diverticulum of bladder	0.005	0.995	0.000
Q64.5 Congenital absence of bladder and urethra	0.005	0.995	0.000
Q64.4 Malformation of urachus	0.005	0.995	0.000
Q64.2 Congenital posterior urethral valves	0.005	0.995	0.000
Q64.1 Exstrophy of urinary bladder	0.005	0.995	0.000
Q64.0 Epispadias	0.005	0.995	0.000
Q07 Other congenital malformations of nervous system	0.005	0.995	0.000
Q21.0 Ventricular septal defect	0.005	0.995	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.005	0.995	0.000
Q63.2 Ectopic kidney	0.005	0.995	0.000
Q05.8 Sacral spina bifida without hydrocephalus	0.005	0.995	0.000
Q05.7 Lumbar spina bifida without hydrocephalus	0.005	0.995	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.005	0.995	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.005	0.995	0.000
Q05.3 Sacral spina bifida with hydrocephalus	0.005	0.995	0.000
Q05.2 Lumbar spina bifida with hydrocephalus	0.005	0.995	0.000
Q05.1 Thoracic spina bifida with hydrocephalus	0.005	0.995	0.000
Q05.0 Cervical spina bifida with hydrocephalus	0.005	0.995	0.000
Q31 Congenital malformations of larynx	0.005	0.995	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.995	0.005
Q67.5 Congenital deformity of spine	0.005	0.995	0.000
S90.8 Other superficial injuries of ankle and foot	0.005	0.995	0.000
T71 Asphyxiation	0.001	0.995	0.004
Q62.8 Other congenital malformations of ureter	0.005	0.995	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.005	0.995	0.000
Q62.6 Malposition of ureter	0.005	0.995	0.000
Q62.4 Agenesis of ureter	0.005	0.995	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.005	0.995	0.000
Q62.2 Congenital megaloureter	0.005	0.995	0.000
Q62.1 Atresia and stenosis of ureter	0.005	0.995	0.000
Q62.0 Congenital hydronephrosis	0.005	0.995	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.005	0.995	0.000
Q34 Other congenital malformations of respiratory system	0.005	0.995	0.000
Q33 Congenital malformations of lung	0.005	0.995	0.000
Q32 Congenital malformations of trachea and bronchus	0.005	0.995	0.000
Q30 Congenital malformations of nose	0.005	0.995	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.005	0.995	0.000
Q75 Other congenital malformations of skull and face bones	0.005	0.995	0.000
Q73 Reduction defects of unspecified limb	0.005	0.995	0.000
Q72 Reduction defects of lower limb	0.005	0.995	0.000
Q71 Reduction defects of upper limb	0.005	0.995	0.000
Q70 Syndactyly	0.005	0.995	0.000
Q69 Polydactyly	0.005	0.995	0.000
Q68 Other congenital musculoskeletal deformities	0.005	0.995	0.000
Q25.6 Stenosis of pulmonary artery	0.005	0.995	0.000
T74 Maltreatment syndromes	0.001	0.995	0.004
T73 Effects of other deprivation	0.001	0.995	0.004
T69 Other effects of reduced temperature	0.001	0.995	0.004
T67 Effects of heat and light	0.001	0.995	0.004
Q66 Congenital deformities of feet	0.005	0.995	0.000
Q22.5 Ebstein's anomaly	0.005	0.995	0.000
S90.1 Contusion of toe(s) without damage to nail	0.005	0.995	0.000
K29.3 Chronic superficial gastritis	0.000	0.995	0.005
Q24.6 Congenital heart block	0.005	0.995	0.000
Q24.4 Congenital subaortic stenosis	0.005	0.995	0.000
Q24.3 Pulmonary infundibular stenosis	0.005	0.995	0.000
Q24.2 Cor triatriatum	0.005	0.995	0.000
Q24.1 Levocardia	0.005	0.995	0.000
Z40 Prophylactic surgery	0.000	0.995	0.005
Q36 Cleft lip	0.004	0.995	0.000
Q24.5 Malformation of coronary vessels	0.005	0.995	0.000
Q90.9 Down's syndrome, unspecified	0.004	0.995	0.000
Q37 Cleft palate with cleft lip	0.004	0.995	0.000
T68 Hypothermia	0.000	0.995	0.004
Q17 Other congenital malformations of ear	0.004	0.995	0.000
Q28 Other congenital malformations of circulatory system	0.004	0.995	0.000
Q35 Cleft palate	0.004	0.995	0.000
Q67.6 Pectus excavatum	0.004	0.995	0.000
Q98.4 Klinefelter's syndrome, unspecified	0.004	0.995	0.000
Q44.6 Cystic disease of liver	0.004	0.995	0.000
Q21.3 Tetralogy of Fallot	0.004	0.995	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.004	0.995	0.000
Q25.8 Other congenital malformations of great arteries	0.004	0.995	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.004	0.995	0.000
Q25.5 Atresia of pulmonary artery	0.004	0.995	0.000
Q25.3 Stenosis of aorta	0.004	0.995	0.000
Q25.2 Atresia of aorta	0.004	0.995	0.000
T66 Unspecified effects of radiation	0.001	0.995	0.004
Q25.1 Coarctation of aorta	0.004	0.995	0.000
Q25.4 Other congenital malformations of aorta	0.004	0.996	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.004	0.996	0.000
Q15 Other congenital malformations of eye	0.004	0.996	0.000
Q13 Congenital malformations of anterior segment of eye	0.004	0.996	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.004	0.996	0.000
Q50-Q56 Congenital malformations of genital organs	0.004	0.996	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.004	0.996	0.000
Q79.5 Other congenital malformations of abdominal wall	0.004	0.996	0.000
Q79.4 Prune belly syndrome	0.004	0.996	0.000
Q79.3 Gastroschisis	0.004	0.996	0.000
Q79.2 Exomphalos	0.004	0.996	0.000
Q79.1 Other congenital malformations of diaphragm	0.004	0.996	0.000
Q79.0 Congenital diaphragmatic hernia	0.004	0.996	0.000
Q21.8 Other congenital malformations of cardiac septa	0.004	0.996	0.000
Q21.4 Aortopulmonary septal defect	0.004	0.996	0.000
Q21.2 Atrioventricular septal defect	0.004	0.996	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.996	0.004
Q74 Other congenital malformations of limb(s)	0.004	0.996	0.000
Q67.8 Other congenital deformities of chest	0.004	0.996	0.000
Q67.7 Pectus carinatum	0.004	0.996	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.004	0.996	0.000
Q67.3 Plagiocephaly	0.004	0.996	0.000
Q67.2 Dolichocephaly	0.004	0.996	0.000
Q67.1 Compression facies	0.004	0.996	0.000
Q67.0 Facial asymmetry	0.004	0.996	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.004	0.996	0.000
S90.2 Contusion of toe(s) with damage to nail	0.004	0.996	0.000
T70.3 Caisson disease [decompression sickness]	0.000	0.996	0.004
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.004	0.996	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.004	0.996	0.000
Q22.6 Hypoplastic right heart syndrome	0.004	0.996	0.000
Q22.4 Congenital tricuspid stenosis	0.004	0.996	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.004	0.996	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.004	0.996	0.000
Q22.1 Congenital pulmonary valve stenosis	0.004	0.996	0.000
Q22.0 Pulmonary valve atresia	0.004	0.996	0.000
Q14 Congenital malformations of posterior segment of eye	0.004	0.996	0.000
Q90.2 Trisomy 21, translocation	0.004	0.996	0.000
Q90.1 Trisomy 21, mosaicism (mitotic nondisjunction)	0.004	0.996	0.000
Q90.0 Trisomy 21, meiotic nondisjunction	0.004	0.996	0.000
Q11.1 Other anophthalmos	0.004	0.996	0.000
Q96.9 Turner's syndrome, unspecified	0.004	0.996	0.000
Q98.9 Sex chromosome abnormality, male phenotype, unspecified	0.004	0.996	0.000
Q98.8 Other specified sex chromosome abnormalities, male phenotype	0.004	0.996	0.000
Q98.7 Male with sex chromosome mosaicism	0.004	0.996	0.000
Q98.6 Male with structurally abnormal sex chromosome	0.004	0.996	0.000
Q98.5 Karyotype 47,XYY	0.004	0.996	0.000
Q98.3 Other male with 46,XX karyotype	0.004	0.996	0.000
Q98.2 Klinefelter's syndrome, male with 46,XX karyotype	0.004	0.996	0.000
Q98.1 Klinefelter's syndrome, male with more than two X chromosomes	0.004	0.996	0.000
Q98.0 Klinefelter's syndrome karyotype 47,XXY	0.004	0.996	0.000
Q18 Other congenital malformations of face and neck	0.004	0.996	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.004	0.996	0.000
Q78.0 Osteogenesis imperfecta	0.004	0.996	0.000
S90-S99 Injuries to the ankle and foot	0.004	0.996	0.000
Q00.2 Iniencephaly	0.004	0.996	0.000
Q00.1 Craniorachischisis	0.004	0.996	0.000
Q00.0 Anencephaly	0.004	0.996	0.000
Q01.9 Encephalocele, unspecified	0.004	0.996	0.000
Q01.8 Encephalocele of other sites	0.004	0.996	0.000
Q01.2 Occipital encephalocele	0.004	0.996	0.000
Q01.1 Nasofrontal encephalocele	0.004	0.996	0.000
Q01.0 Frontal encephalocele	0.004	0.996	0.000
Q03.9 Congenital hydrocephalus, unspecified	0.004	0.996	0.000
Q03.8 Other congenital hydrocephalus	0.004	0.996	0.000
Q03.1 Atresia of foramina of Magendie and Luschka	0.004	0.996	0.000
Q03.0 Malformations of aqueduct of Sylvius	0.004	0.996	0.000
Q04.9 Congenital malformation of brain, unspecified	0.004	0.996	0.000
Q04.8 Other specified congenital malformations of brain	0.004	0.996	0.000
Q04.6 Congenital cerebral cysts	0.004	0.996	0.000
Q04.5 Megalencephaly	0.004	0.996	0.000
Q04.4 Septo-optic dysplasia	0.004	0.996	0.000
Q04.3 Other reduction deformities of brain	0.004	0.996	0.000
Q04.2 Holoprosencephaly	0.004	0.996	0.000
Q04.1 Arhinencephaly	0.004	0.996	0.000
Q04.0 Congenital malformations of corpus callosum	0.004	0.996	0.000
Q06.9 Congenital malformation of spinal cord, unspecified	0.004	0.996	0.000
Q06.8 Other specified congenital malformations of spinal cord	0.004	0.996	0.000
Q06.4 Hydromyelia	0.004	0.996	0.000
Q06.3 Other congenital cauda equina malformations	0.004	0.996	0.000
Q06.2 Diastematomyelia	0.004	0.996	0.000
Q06.1 Hypoplasia and dysplasia of spinal cord	0.004	0.996	0.000
Q06.0 Amyelia	0.004	0.996	0.000
Q66.8 Other congenital deformities of feet	0.004	0.996	0.000
D50.8 Other iron deficiency anaemias	0.000	0.996	0.004
Q31.0 Web of larynx	0.004	0.996	0.000
Q96.8 Other variants of Turner's syndrome	0.004	0.996	0.000
Q96.4 Mosaicism, 45,X/other cell line(s) with abnormal sex chromosome	0.004	0.996	0.000
Q96.3 Mosaicism, 45,X/46,XX or XY	0.004	0.996	0.000
Q96.2 Karyotype 46,X with abnormal sex chromosome, except iso (Xq)	0.004	0.996	0.000
Q96.1 Karyotype 46,X iso (Xq)	0.004	0.996	0.000
Q96.0 Karyotype 45,X	0.004	0.996	0.000
Q65 Congenital deformities of hip	0.004	0.996	0.000
F60.9 Personality disorder, unspecified	0.004	0.996	0.000
T75 Effects of other external causes	0.001	0.996	0.003
S99.9 Unspecified injury of ankle and foot	0.004	0.996	0.000
Q23 Congenital malformations of aortic and mitral valves	0.004	0.996	0.000
Q91.7 Patau's syndrome, unspecified	0.004	0.996	0.000
Q91.6 Trisomy 13, translocation	0.004	0.996	0.000
Q91.5 Trisomy 13, mosaicism (mitotic nondisjunction)	0.004	0.996	0.000
Q91.4 Trisomy 13, meiotic nondisjunction	0.004	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations