TreeWAS – Variant ID: rs1278352

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
R47.8 Other and unspecified speech disturbances	0.000	0.808	0.192
R47 Speech disturbances, not elsewhere classified	0.000	0.958	0.042
R47.1 Dysarthria and anarthria	0.000	0.970	0.030
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.000	0.979	0.021
C53.9 Cervix uteri, unspecified	0.018	0.982	0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen	0.017	0.983	0.000
Y83.4 Other reconstructive surgery	0.012	0.988	0.000
G25.8 Other specified extrapyramidal and movement disorders	0.000	0.988	0.012
C53 Malignant neoplasm of cervix uteri	0.011	0.989	0.000
L97 Ulcer of lower limb, not elsewhere classified	0.011	0.989	0.000
G25.3 Myoclonus	0.000	0.990	0.010
G25 Other extrapyramidal and movement disorders	0.000	0.990	0.010
A41.1 Septicaemia due to other specified staphylococcus	0.010	0.990	0.000
C53.0 Endocervix	0.009	0.991	0.000
R47-R49 Symptoms and signs involving speech and voice	0.000	0.992	0.008
C53.8 Overlapping lesion of cervix uteri	0.008	0.992	0.000
C53.1 Exocervix	0.008	0.992	0.000
G25.2 Other specified forms of tremor	0.000	0.992	0.008
A49.0 Staphylococcal infection, unspecified	0.008	0.992	0.000
A41.9 Septicaemia, unspecified	0.007	0.993	0.000
G25.6 Drug-induced tics and other tics of organic origin	0.000	0.993	0.007
G25.4 Drug-induced chorea	0.000	0.993	0.007
G25.5 Other chorea	0.000	0.993	0.007
G25.0 Essential tremor	0.000	0.993	0.007
G25.1 Drug-induced tremor	0.000	0.993	0.007
A41 Other septicaemia	0.007	0.993	0.000
G25.9 Extrapyramidal and movement disorder, unspecified	0.000	0.993	0.007
F32.2 Severe depressive episode without psychotic symptoms	0.007	0.993	0.000
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.000	0.993	0.007
D63.8 Anaemia in other chronic diseases classified elsewhere	0.006	0.994	0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified	0.000	0.994	0.006
A49 Bacterial infection of unspecified site	0.006	0.994	0.000
F32.3 Severe depressive episode with psychotic symptoms	0.005	0.995	0.000
A49.9 Bacterial infection, unspecified	0.005	0.995	0.000
O04.4 Incomplete, without complication	0.005	0.995	0.000
O04.9 Complete or unspecified, without complication	0.005	0.995	0.000
A41.0 Septicaemia due to Staphylococcus aureus	0.005	0.995	0.000
A41.3 Septicaemia due to Haemophilus influenzae	0.005	0.995	0.000
A41.4 Septicaemia due to anaerobes	0.005	0.995	0.000
N03.9 Unspecified	0.005	0.995	0.000
A30-A49 Other bacterial diseases	0.005	0.995	0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.000	0.995	0.005
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.005	0.995	0.000
A48 Other bacterial diseases, not elsewhere classified	0.005	0.995	0.000
A49.2 Haemophilus influenzae infection, unspecified	0.005	0.995	0.000
A48.1 Legionnaires' disease	0.005	0.995	0.000
O04 Medical abortion	0.005	0.995	0.000
A41.8 Other specified septicaemia	0.005	0.995	0.000
R48.8 Other and unspecified symbolic dysfunctions	0.000	0.995	0.004
R48.2 Apraxia	0.000	0.995	0.004
R48.1 Agnosia	0.000	0.995	0.004
A49.3 Mycoplasma infection, unspecified	0.004	0.995	0.000
K09.8 Other cysts of oral region, not elsewhere classified	0.000	0.995	0.004
O04.1 Incomplete, complicated by delayed or excessive haemorrhage	0.004	0.996	0.000
A41.2 Septicaemia due to unspecified staphylococcus	0.004	0.996	0.000
R48.0 Dyslexia and alexia	0.000	0.996	0.004
A49.1 Streptococcal infection, unspecified	0.004	0.996	0.000
S30.2 Contusion of external genital organs	0.004	0.996	0.000
A42 Actinomycosis	0.004	0.996	0.000
A48.8 Other specified bacterial diseases	0.004	0.996	0.000
F32 Depressive episode	0.004	0.996	0.000
A44 Bartonellosis	0.004	0.996	0.000
A43 Nocardiosis	0.004	0.996	0.000
A37 Whooping cough	0.004	0.996	0.000
A36 Diphtheria	0.004	0.996	0.000
A32 Listeriosis	0.004	0.996	0.000
A30 Leprosy [Hansen's disease]	0.004	0.996	0.000
A38 Scarlet fever	0.004	0.996	0.000
A35 Other tetanus	0.004	0.996	0.000
A34 Obstetrical tetanus	0.004	0.996	0.000
A33 Tetanus neonatorum	0.004	0.996	0.000
R47.0 Dysphasia and aphasia	0.000	0.996	0.004
S32.81 Fracture of other and unspecified parts of lumbar spine and pelvis (open)	0.000	0.996	0.004
S82.00 Fracture of patella (closed)	0.004	0.996	0.000
A48.4 Brazilian purpuric fever	0.004	0.996	0.000
A48.2 Nonpneumonic Legionnaires' disease [Pontiac fever]	0.004	0.996	0.000
A48.0 Gas gangrene	0.004	0.996	0.000
S32.40 Fracture of acetabulum (closed)	0.000	0.996	0.004
S32 Fracture of lumbar spine and pelvis	0.000	0.996	0.004
A39 Meningococcal infection	0.004	0.996	0.000
O04.7 Complete or unspecified, complicated by embolism	0.003	0.996	0.000
O04.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.003	0.996	0.000
O04.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.003	0.996	0.000
O04.3 Incomplete, with other and unspecified complications	0.003	0.996	0.000
O04.2 Incomplete, complicated by embolism	0.003	0.996	0.000
O04.0 Incomplete, complicated by genital tract and pelvic infection	0.003	0.996	0.000
A48.3 Toxic shock syndrome	0.003	0.996	0.000
S32.4 Fracture of acetabulum	0.000	0.996	0.004
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.004	0.996	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.000	0.996	0.004
M22.4 Chondromalacia patellae	0.004	0.996	0.000
A31 Infection due to other mycobacteria	0.003	0.997	0.000
F32.8 Other depressive episodes	0.003	0.997	0.000
G20-G26 Extrapyramidal and movement disorders	0.000	0.997	0.003
Z81.8 Family history of other mental and behavioural disorders	0.003	0.997	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.003	0.997	0.000
M72.27 Plantar fascial fibromatosis-Ankle/Foot	0.003	0.997	0.000
S32.5 Fracture of pubis	0.000	0.997	0.003
G20 Parkinson's disease	0.000	0.997	0.003
A42.9 Actinomycosis, unspecified	0.003	0.997	0.000
A39.0 Meningococcal meningitis	0.003	0.997	0.000
Y83.3 Surgical operation with formation of external stoma	0.003	0.997	0.000
A42.8 Other forms of actinomycosis	0.003	0.997	0.000
A42.7 Actinomycotic septicaemia	0.003	0.997	0.000
A42.2 Cervicofacial actinomycosis	0.003	0.997	0.000
A42.1 Abdominal actinomycosis	0.003	0.997	0.000
A42.0 Pulmonary actinomycosis	0.003	0.997	0.000
S83.3 Tear of articular cartilage of knee, current	0.003	0.997	0.000
M87.2 Osteonecrosis due to previous trauma	0.003	0.997	0.000
O04.8 Complete or unspecified, with other and unspecified complications	0.003	0.997	0.000
S32.0 Fracture of lumbar vertebra	0.000	0.997	0.003
A30.9 Leprosy, unspecified	0.003	0.997	0.000
A30.8 Other forms of leprosy	0.003	0.997	0.000
A30.5 Lepromatous leprosy	0.003	0.997	0.000
A30.4 Borderline lepromatous leprosy	0.003	0.997	0.000
A30.3 Borderline leprosy	0.003	0.997	0.000
A30.2 Borderline tuberculoid leprosy	0.003	0.997	0.000
A30.1 Tuberculoid leprosy	0.003	0.997	0.000
A30.0 Indeterminate leprosy	0.003	0.997	0.000
A32.9 Listeriosis, unspecified	0.003	0.997	0.000
A32.8 Other forms of listeriosis	0.003	0.997	0.000
A32.7 Listerial septicaemia	0.003	0.997	0.000
A32.1 Listerial meningitis and meningoencephalitis	0.003	0.997	0.000
A32.0 Cutaneous listeriosis	0.003	0.997	0.000
A36.9 Diphtheria, unspecified	0.003	0.997	0.000
A36.8 Other diphtheria	0.003	0.997	0.000
A36.3 Cutaneous diphtheria	0.003	0.997	0.000
A36.2 Laryngeal diphtheria	0.003	0.997	0.000
A36.1 Nasopharyngeal diphtheria	0.003	0.997	0.000
A36.0 Pharyngeal diphtheria	0.003	0.997	0.000
A37.9 Whooping cough, unspecified	0.003	0.997	0.000
A37.8 Whooping cough due to other Bordetella species	0.003	0.997	0.000
A37.1 Whooping cough due to Bordetella parapertussis	0.003	0.997	0.000
A37.0 Whooping cough due to Bordetella pertussis	0.003	0.997	0.000
A43.9 Nocardiosis, unspecified	0.003	0.997	0.000
A43.8 Other forms of nocardiosis	0.003	0.997	0.000
A43.1 Cutaneous nocardiosis	0.003	0.997	0.000
A43.0 Pulmonary nocardiosis	0.003	0.997	0.000
A44.9 Bartonellosis, unspecified	0.003	0.997	0.000
A44.8 Other forms of bartonellosis	0.003	0.997	0.000
A44.1 Cutaneous and mucocutaneous bartonellosis	0.003	0.997	0.000
A44.0 Systemic bartonellosis	0.003	0.997	0.000
S32.7 Multiple fractures of lumbar spine and pelvis	0.000	0.997	0.003
S30 Superficial injury of abdomen, lower back and pelvis	0.003	0.997	0.000
S32.50 Fracture of pubis (closed)	0.000	0.997	0.003
G23 Other degenerative diseases of basal ganglia	0.000	0.997	0.003
S30.0 Contusion of lower back and pelvis	0.003	0.997	0.000
F30.1 Mania without psychotic symptoms	0.003	0.997	0.000
S32.2 Fracture of coccyx	0.000	0.997	0.003
S32.41 Fracture of acetabulum (open)	0.000	0.997	0.003
A39.9 Meningococcal infection, unspecified	0.003	0.997	0.000
A39.8 Other meningococcal infections	0.003	0.997	0.000
A39.5 Meningococcal heart disease	0.003	0.997	0.000
A39.3 Chronic meningococcaemia	0.003	0.997	0.000
A39.2 Acute meningococcaemia	0.003	0.997	0.000
A39.1 Waterhouse-Friderichsen syndrome	0.003	0.997	0.000
M87.9 Osteonecrosis, unspecified	0.003	0.997	0.000
F30 Manic episode	0.003	0.997	0.000
R49 Voice disturbances	0.001	0.997	0.002
A31.8 Other mycobacterial infections	0.003	0.997	0.000
M19.99 Arthrosis, unspecified (Site unspecified)	0.003	0.997	0.000
G23.8 Other specified degenerative diseases of basal ganglia	0.000	0.997	0.003
S83.2 Tear of meniscus, current	0.003	0.997	0.000
A31.1 Cutaneous mycobacterial infection	0.003	0.997	0.000
M87.98 Osteonecrosis, unspecified (Other)	0.003	0.997	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.000	0.997	0.003
G22 Parkinsonism in diseases classified elsewhere	0.000	0.997	0.003
M87.96 Osteonecrosis, unspecified (Lower leg)	0.003	0.997	0.000
F30.0 Hypomania	0.003	0.997	0.000
S83.7 Injury to multiple structures of knee	0.003	0.997	0.000
S83.0 Dislocation of patella	0.003	0.997	0.000
J22 Unspecified acute lower respiratory infection	0.003	0.997	0.000
M47.82 Other spondylosis (Cervical region)	0.003	0.997	0.000
S32.3 Fracture of ilium	0.000	0.997	0.003
A31.0 Pulmonary mycobacterial infection	0.002	0.997	0.000
T14.6 Injury of tendons and muscles of unspecified body region	0.003	0.997	0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene	0.003	0.997	0.000
I49.5 Sick sinus syndrome	0.003	0.997	0.000
S32.1 Fracture of sacrum	0.000	0.997	0.003
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)	0.003	0.997	0.000
M87.85 Other osteonecrosis (Pelvic region and thigh)	0.003	0.997	0.000
S32.51 Fracture of pubis (open)	0.000	0.997	0.002
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.003	0.997	0.000
S82.0 Fracture of patella	0.003	0.997	0.000
A46 Erysipelas	0.002	0.997	0.000
M87 Osteonecrosis	0.003	0.997	0.000
M87.8 Other osteonecrosis	0.002	0.997	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.002	0.997	0.000
M87.24 Osteonecrosis due to previous trauma (Hand)	0.002	0.997	0.000
S32.00 Fracture of lumbar vertebra (closed)	0.000	0.997	0.003
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.003	0.997	0.000
C55 Malignant neoplasm of uterus, part unspecified	0.003	0.997	0.000
H65.3 Chronic mucoid otitis media	0.000	0.997	0.003
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.000	0.997	0.003
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.002	0.997	0.000
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.000	0.997	0.002
A49.8 Other bacterial infections of unspecified site	0.002	0.997	0.000
H04.1 Other disorders of lachrymal gland	0.003	0.997	0.000
M87.29 Osteonecrosis due to previous trauma (Site unspecified)	0.002	0.998	0.000
M87.28 Osteonecrosis due to previous trauma (Other)	0.002	0.998	0.000
M87.26 Osteonecrosis due to previous trauma (Lower leg)	0.002	0.998	0.000
M87.23 Osteonecrosis due to previous trauma (Forearm)	0.002	0.998	0.000
M87.22 Osteonecrosis due to previous trauma (Upper arm)	0.002	0.998	0.000
M87.21 Osteonecrosis due to previous trauma (Shoulder region)	0.002	0.998	0.000
G21 Secondary Parkinsonism	0.000	0.998	0.002
S32.01 Fracture of lumbar vertebra (open)	0.000	0.998	0.002
A31.9 Mycobacterial infection, unspecified	0.002	0.998	0.000
F30.2 Mania with psychotic symptoms	0.002	0.998	0.000
O63.9 Long labour, unspecified	0.000	0.998	0.002
S83.1 Dislocation of knee	0.002	0.998	0.000
S32.71 Multiple fractures of lumbar spine and pelvis (open)	0.000	0.998	0.002
L73.9 Follicular disorder, unspecified	0.002	0.998	0.000
F33.9 Recurrent depressive disorder, unspecified	0.002	0.998	0.000
F30-F39 Mood [affective] disorders	0.002	0.998	0.000
G23.9 Degenerative disease of basal ganglia, unspecified	0.000	0.998	0.002
G23.3 Multiple system atrophy, cerebellar type	0.000	0.998	0.002
G23.2 Striatonigral degeneration	0.000	0.998	0.002
G23.0 Hallervorden-Spatz disease	0.000	0.998	0.002
S30.1 Contusion of abdominal wall	0.002	0.998	0.000
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.002	0.998	0.000
Q61.0 Congenital single renal cyst	0.002	0.998	0.000
T14.0 Superficial injury of unspecified body region	0.002	0.998	0.000
S32.21 Fracture of coccyx (open)	0.000	0.998	0.002
S32.20 Fracture of coccyx (closed)	0.000	0.998	0.002
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.002	0.998	0.000
M87.94 Osteonecrosis, unspecified (Hand)	0.002	0.998	0.000
M87.93 Osteonecrosis, unspecified (Forearm)	0.002	0.998	0.000
M87.92 Osteonecrosis, unspecified (Upper arm)	0.002	0.998	0.000
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.002	0.998	0.000
F33 Recurrent depressive disorder	0.002	0.998	0.000
A39.4 Meningococcaemia, unspecified	0.002	0.998	0.000
F30.8 Other manic episodes	0.002	0.998	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.002	0.998	0.000
R49.2 Hypernasality and hyponasality	0.001	0.998	0.002
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)	0.002	0.998	0.000
K38.8 Other specified diseases of appendix	0.002	0.998	0.000
L05.0 Pilonidal cyst with abscess	0.002	0.998	0.000
T14 Injury of unspecified body region	0.002	0.998	0.000
Y83.5 Amputation of limb(s)	0.002	0.998	0.000
C51-C58 Malignant neoplasms of female genital organs	0.002	0.998	0.000
A40 Streptococcal septicaemia	0.002	0.998	0.000
S32.31 Fracture of ilium (open)	0.000	0.998	0.002
D36.7 Other specified sites	0.002	0.998	0.000
R49.1 Aphonia	0.001	0.998	0.002
F30.9 Manic episode, unspecified	0.002	0.998	0.000
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]	0.000	0.998	0.002
T91.3 Sequelae of injury of spinal cord	0.000	0.998	0.002
F38 Other mood [affective] disorders	0.002	0.998	0.000
S32.11 Fracture of sacrum (open)	0.000	0.998	0.002
S82.01 Fracture of patella (open)	0.002	0.998	0.000
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.002	0.998	0.000
M87.1 Osteonecrosis due to drugs	0.002	0.998	0.000
M87.89 Other osteonecrosis (Site unspecified)	0.002	0.998	0.000
M87.88 Other osteonecrosis (Other)	0.002	0.998	0.000
M87.87 Other osteonecrosis (Ankle and foot)	0.002	0.998	0.000
M87.86 Other osteonecrosis (Lower leg)	0.002	0.998	0.000
M87.84 Other osteonecrosis (Hand)	0.002	0.998	0.000
M87.83 Other osteonecrosis (Forearm)	0.002	0.998	0.000
M87.82 Other osteonecrosis (Upper arm)	0.002	0.998	0.000
M87.81 Other osteonecrosis (Shoulder region)	0.002	0.998	0.000
M87.80 Other osteonecrosis (Multiple sites)	0.002	0.998	0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.002	0.998	0.000
M87.3 Other secondary osteonecrosis	0.002	0.998	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.002	0.998	0.000
F34 Persistent mood [affective] disorders	0.002	0.998	0.000
G21.9 Secondary Parkinsonism, unspecified	0.000	0.998	0.002
T93.1 Sequelae of fracture of femur	0.002	0.998	0.000
K86.2 Cyst of pancreas	0.002	0.998	0.000
M47.12 Other spondylosis with myelopathy (Cervical region)	0.002	0.998	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.002	0.998	0.000
M87.0 Idiopathic aseptic necrosis of bone	0.002	0.998	0.000
T14.1 Open wound of unspecified body region	0.002	0.998	0.000
G21.8 Other secondary Parkinsonism	0.000	0.998	0.002
G21.3 Postencephalitic Parkinsonism	0.000	0.998	0.002
G21.2 Secondary Parkinsonism due to other external agents	0.000	0.998	0.002
F38.0 Other single mood [affective] disorders	0.002	0.998	0.000
N03 Chronic nephritic syndrome	0.002	0.998	0.000
A40.3 Septicaemia due to Streptococcus pneumoniae	0.002	0.998	0.000
I63.8 Other cerebral infarction	0.000	0.998	0.002
R10.2 Pelvic and perineal pain	0.002	0.998	0.000
S82.31 Fracture of lower end of tibia (open)	0.002	0.998	0.000
G21.0 Malignant neuroleptic syndrome	0.000	0.998	0.002
T14.3 Dislocation, sprain and strain of unspecified body region	0.002	0.998	0.000
F33.8 Other recurrent depressive disorders	0.002	0.998	0.000
F33.4 Recurrent depressive disorder, currently in remission	0.002	0.998	0.000
F32.0 Mild depressive episode	0.002	0.998	0.000
G21.1 Other drug-induced secondary Parkinsonism	0.000	0.998	0.002
T14.2 Fracture of unspecified body region	0.002	0.998	0.000
T14.8 Other injuries of unspecified body region	0.002	0.998	0.000
T14.7 Crushing injury and traumatic amputation of unspecified body region	0.002	0.998	0.000
T14.5 Injury of blood vessel(s) of unspecified body region	0.002	0.998	0.000
T14.4 Injury of nerve(s) of unspecified body region	0.002	0.998	0.000
S32.30 Fracture of ilium (closed)	0.000	0.998	0.002
G21.4 Vascular parkinsonism	0.000	0.998	0.002
I86.1 Scrotal varices	0.002	0.998	0.000
N03.2 Diffuse membranous glomerulonephritis	0.002	0.998	0.000
D58.0 Hereditary spherocytosis	0.000	0.998	0.002
F34.1 Dysthymia	0.002	0.998	0.000
C58 Malignant neoplasm of placenta	0.002	0.998	0.000
H65.2 Chronic serous otitis media	0.000	0.998	0.002
C57 Malignant neoplasm of other and unspecified female genital organs	0.002	0.998	0.000
Z81 Family history of mental and behavioural disorders	0.002	0.998	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.002	0.998	0.000
F38.1 Other recurrent mood [affective] disorders	0.002	0.998	0.000
S32.10 Fracture of sacrum (closed)	0.000	0.998	0.002
R49.8 Other and unspecified voice disturbances	0.001	0.998	0.001
S81.8 Open wound of other parts of lower leg	0.002	0.998	0.000
N46 Male infertility	0.002	0.998	0.000
M87.19 Osteonecrosis due to drugs (Site unspecified)	0.002	0.998	0.000
M87.18 Osteonecrosis due to drugs (Other)	0.002	0.998	0.000
M87.17 Osteonecrosis due to drugs (Ankle and foot)	0.002	0.998	0.000
M87.16 Osteonecrosis due to drugs (Lower leg)	0.002	0.998	0.000
M87.15 Osteonecrosis due to drugs (Pelvic region and thigh)	0.002	0.998	0.000
M87.14 Osteonecrosis due to drugs (Hand)	0.002	0.998	0.000
M87.13 Osteonecrosis due to drugs (Forearm)	0.002	0.998	0.000
M87.12 Osteonecrosis due to drugs (Upper arm)	0.002	0.998	0.000
M87.11 Osteonecrosis due to drugs (Shoulder region)	0.002	0.998	0.000
M87.10 Osteonecrosis due to drugs (Multiple sites)	0.002	0.998	0.000
M72.2 Plantar fascial fibromatosis	0.002	0.998	0.000
S82.3 Fracture of lower end of tibia	0.002	0.998	0.000
Z81.1 Family history of alcohol abuse	0.002	0.998	0.000
J81 Pulmonary oedema	0.002	0.998	0.000
M87.39 Other secondary osteonecrosis (Site unspecified)	0.002	0.998	0.000
M87.38 Other secondary osteonecrosis (Other)	0.002	0.998	0.000
M87.37 Other secondary osteonecrosis (Ankle and foot)	0.002	0.998	0.000
M87.36 Other secondary osteonecrosis (Lower leg)	0.002	0.998	0.000
M87.34 Other secondary osteonecrosis (Hand)	0.002	0.998	0.000
M87.33 Other secondary osteonecrosis (Forearm)	0.002	0.998	0.000
M87.32 Other secondary osteonecrosis (Upper arm)	0.002	0.998	0.000
M87.31 Other secondary osteonecrosis (Shoulder region)	0.002	0.998	0.000
M87.30 Other secondary osteonecrosis (Multiple sites)	0.002	0.998	0.000
A40.1 Septicaemia due to streptococcus, group B	0.002	0.998	0.000
F34.9 Persistent mood [affective] disorder, unspecified	0.002	0.998	0.000
F34.8 Other persistent mood [affective] disorders	0.002	0.998	0.000
F34.0 Cyclothymia	0.002	0.998	0.000
F38.8 Other specified mood [affective] disorders	0.002	0.998	0.000
L90.5 Scar conditions and fibrosis of skin	0.002	0.998	0.000
X49.9 Unspecified place	0.000	0.998	0.002
Z57.5 Occupational exposure to toxic agents in other industries	0.000	0.998	0.002
M87.09 Idiopathic aseptic necrosis of bone (Site unspecified)	0.002	0.998	0.000
M87.08 Idiopathic aseptic necrosis of bone (Other)	0.002	0.998	0.000
M87.07 Idiopathic aseptic necrosis of bone (Ankle and foot)	0.002	0.998	0.000
M87.06 Idiopathic aseptic necrosis of bone (Lower leg)	0.002	0.998	0.000
M87.04 Idiopathic aseptic necrosis of bone (Hand)	0.002	0.998	0.000
M87.03 Idiopathic aseptic necrosis of bone (Forearm)	0.002	0.998	0.000
M87.02 Idiopathic aseptic necrosis of bone (Upper arm)	0.002	0.998	0.000
M87.01 Idiopathic aseptic necrosis of bone (Shoulder region)	0.002	0.998	0.000
M87.00 Idiopathic aseptic necrosis of bone (Multiple sites)	0.002	0.998	0.000
M87.35 Other secondary osteonecrosis (Pelvic region and thigh)	0.002	0.998	0.000
G24.5 Blepharospasm	0.001	0.998	0.000
K38.9 Disease of appendix, unspecified	0.002	0.998	0.000
S84.1 Injury of peroneal nerve at lower leg level	0.002	0.998	0.000
C52 Malignant neoplasm of vagina	0.002	0.998	0.000
A40.2 Septicaemia due to streptococcus, group D	0.002	0.998	0.000
N95.8 Other specified menopausal and perimenopausal disorders	0.002	0.998	0.000
S61.8 Open wound of other parts of wrist and hand	0.000	0.998	0.002
N03.7 Diffuse crescentic glomerulonephritis	0.002	0.998	0.000
N03.6 Dense deposit disease	0.002	0.998	0.000
N03.4 Diffuse endocapillary proliferative glomerulonephritis	0.002	0.998	0.000
N03.3 Diffuse mesangial proliferative glomerulonephritis	0.002	0.998	0.000
N03.1 Focal and segmental glomerular lesions	0.002	0.998	0.000
N03.0 Minor glomerular abnormality	0.002	0.998	0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.002	0.998	0.000
E29.1 Testicular hypofunction	0.002	0.998	0.000
N73.9 Female pelvic inflammatory disease, unspecified	0.002	0.998	0.000
T79.3 Post-traumatic wound infection, not elsewhere classified	0.000	0.998	0.002
G24 Dystonia	0.001	0.998	0.001
C51 Malignant neoplasm of vulva	0.002	0.998	0.000
M87.05 Idiopathic aseptic necrosis of bone (Pelvic region and thigh)	0.001	0.998	0.000
S82.81 Fractures of other parts of lower leg (open)	0.000	0.998	0.002
A41.5 Septicaemia due to other Gram-negative organisms	0.002	0.998	0.000
T14.21 Fracture of unspecified body region (open)	0.001	0.998	0.000
T14.20 Fracture of unspecified body region (closed)	0.001	0.998	0.000
M72.29 Plantar fascial fibromatosis-Site unspec	0.002	0.998	0.000
B44.9 Aspergillosis, unspecified	0.002	0.998	0.000
N03.5 Diffuse mesangiocapillary glomerulonephritis	0.001	0.998	0.000
S84 Injury of nerves at lower leg level	0.002	0.998	0.000
T14.9 Injury, unspecified	0.001	0.998	0.000
S82.30 Fracture of lower end of tibia (closed)	0.002	0.998	0.000
C57.8 Overlapping lesion of female genital organs	0.001	0.998	0.000
C57.7 Other specified female genital organs	0.001	0.998	0.000
C57.4 Uterine adnexa, unspecified	0.001	0.998	0.000
C57.3 Parametrium	0.001	0.998	0.000
C57.2 Round ligament	0.001	0.998	0.000
C57.1 Broad ligament	0.001	0.998	0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.002	0.998	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.002	0.998	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.002	0.998	0.000
Z81.4 Family history of other substance abuse	0.001	0.998	0.000
Z81.3 Family history of other psychoactive substance abuse	0.001	0.998	0.000
Z81.2 Family history of tobacco abuse	0.001	0.998	0.000
Z81.0 Family history of mental retardation	0.001	0.998	0.000
A40.0 Septicaemia due to streptococcus, group A	0.001	0.998	0.000
M72.28 Plantar fascial fibromatosis-Other	0.001	0.998	0.000
M72.26 Plantar fascial fibromatosis-Lower Leg	0.001	0.998	0.000
M72.25 Plantar fascial fibromatosis-Pelvic/Thigh	0.001	0.998	0.000
M72.24 Plantar fascial fibromatosis-Hand	0.001	0.998	0.000
M72.23 Plantar fascial fibromatosis-Forearm	0.001	0.998	0.000
M72.22 Plantar fascial fibromatosis-Upper arm	0.001	0.998	0.000
M72.21 Plantar fascial fibromatosis-Shldr region	0.001	0.998	0.000
M72.20 Plantar fascial fibromatosis-Mult sites	0.001	0.998	0.000
M79.28 Neuralgia and neuritis, unspecified (Other)	0.002	0.998	0.000
C57.0 Fallopian tube	0.001	0.998	0.000
K63.9 Disease of intestine, unspecified	0.002	0.998	0.000
S82 Fracture of lower leg, including ankle	0.002	0.998	0.000
M25.56 Pain in joint (Lower leg)	0.002	0.998	0.000
C57.9 Female genital organ, unspecified	0.001	0.998	0.000
S80-S89 Injuries to the knee and lower leg	0.002	0.998	0.000
D04.6 Skin of upper limb, including shoulder	0.002	0.998	0.000
N03.8 Other	0.001	0.998	0.000
F39 Unspecified mood [affective] disorder	0.001	0.998	0.000
S82.51 Fracture of medial malleolus (open)	0.001	0.998	0.000
S82.5 Fracture of medial malleolus	0.001	0.998	0.000
T79.5 Traumatic anuria	0.000	0.998	0.001
F17.2 Dependence syndrome	0.000	0.998	0.002
G24.4 Idiopathic orofacial dystonia	0.001	0.998	0.001
G24.2 Idiopathic nonfamilial dystonia	0.001	0.998	0.001
S41.0 Open wound of shoulder	0.001	0.998	0.000
M47.16 Other spondylosis with myelopathy (Lumbar region)	0.001	0.999	0.000
B44.1 Other pulmonary aspergillosis	0.001	0.999	0.000
C51.8 Overlapping lesion of vulva	0.001	0.999	0.000
C51.2 Clitoris	0.001	0.999	0.000
C51.1 Labium minus	0.001	0.999	0.000
L23.1 Allergic contact dermatitis due to adhesives	0.001	0.999	0.000
T91.1 Sequelae of fracture of spine	0.000	0.999	0.001
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.000	0.999	0.001
V80.9 Rider or occupant injured in other and unspecified transport accidents	0.001	0.999	0.000
Z91.8 Personal history of other specified risk-factors, not elsewhere classified	0.001	0.999	0.000
G24.1 Idiopathic familial dystonia	0.001	0.999	0.001
A40.8 Other streptococcal septicaemia	0.001	0.999	0.000
S84.9 Injury of unspecified nerve at lower leg level	0.001	0.999	0.000
S84.8 Injury of other nerves at lower leg level	0.001	0.999	0.000
S84.7 Injury of multiple nerves at lower leg level	0.001	0.999	0.000
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.001	0.999	0.000
S84.0 Injury of tibial nerve at lower leg level	0.001	0.999	0.000
H65 Nonsuppurative otitis media	0.000	0.999	0.001
G24.0 Drug-induced dystonia	0.001	0.999	0.001
R52.9 Pain, unspecified	0.000	0.999	0.001
T09.3 Injury of spinal cord, level unspecified	0.001	0.999	0.000
K38 Other diseases of appendix	0.001	0.999	0.000
T09 Other injuries of spine and trunk, level unspecified	0.001	0.999	0.000
A40.9 Streptococcal septicaemia, unspecified	0.001	0.999	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.001	0.999	0.000
K09.1 Developmental (nonodontogenic) cysts of oral region	0.000	0.999	0.001
S82.9 Fracture of lower leg, part unspecified	0.001	0.999	0.000
S82.7 Multiple fractures of lower leg	0.001	0.999	0.000
S86 Injury of muscle and tendon at lower leg level	0.001	0.999	0.000
T91 Sequelae of injuries of neck and trunk	0.000	0.999	0.001
L50.9 Urticaria, unspecified	0.000	0.999	0.001
M47.1 Other spondylosis with myelopathy	0.001	0.999	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.001	0.999	0.000
G24.8 Other dystonia	0.001	0.999	0.001
G24.3 Spasmodic torticollis	0.001	0.999	0.001
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.001	0.999	0.000
Z91.2 Personal history of poor personal hygiene	0.001	0.999	0.000
S88 Traumatic amputation of lower leg	0.001	0.999	0.000
S85 Injury of blood vessels at lower leg level	0.001	0.999	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.001	0.999	0.000
C51.9 Vulva, unspecified	0.001	0.999	0.000
H02.5 Other disorders affecting eyelid function	0.001	0.999	0.000
H66.9 Otitis media, unspecified	0.000	0.999	0.001
T91.9 Sequelae of unspecified injury of neck and trunk	0.000	0.999	0.001
D63 Anaemia in chronic diseases classified elsewhere	0.001	0.999	0.000
T08 Fracture of spine, level unspecified	0.001	0.999	0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.001	0.999	0.000
I49.4 Other and unspecified premature depolarisation	0.001	0.999	0.000
S81.7 Multiple open wounds of lower leg	0.001	0.999	0.000
T09.9 Unspecified injury of trunk, level unspecified	0.001	0.999	0.000
T91.2 Sequelae of other fracture of thorax and pelvis	0.000	0.999	0.001
S81 Open wound of lower leg	0.001	0.999	0.000
M47.14 Other spondylosis with myelopathy (Thoracic region)	0.001	0.999	0.000
C51.0 Labium majus	0.001	0.999	0.000
H65.1 Other acute nonsuppurative otitis media	0.000	0.999	0.001
I49.8 Other specified cardiac arrhythmias	0.001	0.999	0.000
S46.2 Injury of muscle and tendon of other parts of biceps	0.000	0.999	0.001
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.001	0.999	0.000
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.001	0.999	0.000
U80.0 Penicillin resistant agent	0.001	0.999	0.000
T13 Other injuries of lower limb, level unspecified	0.001	0.999	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.001	0.999	0.000
T13.9 Unspecified injury of lower limb, level unspecified	0.001	0.999	0.000
T13.1 Open wound of lower limb, level unspecified	0.001	0.999	0.000
S87 Crushing injury of lower leg	0.001	0.999	0.000
S82.90 Fracture of lower leg, part unspecified (closed)	0.001	0.999	0.000
K38.3 Fistula of appendix	0.001	0.999	0.000
N42.0 Calculus of prostate	0.000	0.999	0.001
T09.8 Other specified injuries of trunk, level unspecified	0.001	0.999	0.000
T09.6 Traumatic amputation of trunk, level unspecified	0.001	0.999	0.000
T09.5 Injury of unspecified muscle and tendon of trunk	0.001	0.999	0.000
T09.4 Injury of unspecified nerve, spinal nerve root and plexus of trunk	0.001	0.999	0.000
T09.1 Open wound of trunk, level unspecified	0.001	0.999	0.000
B07 Viral warts	0.000	0.999	0.001
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.001	0.999	0.000
S82.71 Multiple fractures of lower leg (open)	0.001	0.999	0.000
S82.70 Multiple fractures of lower leg (closed)	0.001	0.999	0.000
S82.91 Fracture of lower leg, part unspecified (open)	0.001	0.999	0.000
G24.9 Dystonia, unspecified	0.000	0.999	0.001
I86.2 Pelvic varices	0.001	0.999	0.000
Q51.3 Bicornate uterus	0.000	0.999	0.001
S46.0 Injury of tendon of the rotator cuff of shoulder	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations