TreeWAS – Variant ID: rs12794618

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H40.9 Glaucoma, unspecified	0.776	0.224	0.000
H40 Glaucoma	0.767	0.233	0.000
H40.2 Primary angle-closure glaucoma	0.758	0.242	0.000
H40.1 Primary open-angle glaucoma	0.727	0.273	0.000
H40.4 Glaucoma secondary to eye inflammation	0.563	0.437	0.000
H40.6 Glaucoma secondary to drugs	0.550	0.450	0.000
H40.3 Glaucoma secondary to eye trauma	0.550	0.450	0.000
H40.8 Other glaucoma	0.530	0.470	0.000
H40.5 Glaucoma secondary to other eye disorders	0.494	0.506	0.000
H40.0 Glaucoma suspect	0.458	0.542	0.000
H40-H42 Glaucoma	0.320	0.680	0.000
H42 Glaucoma in diseases classified elsewhere	0.230	0.770	0.000
H42.8 Glaucoma in other diseases classified elsewhere	0.165	0.835	0.000
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases	0.165	0.835	0.000
S72.00 Fracture of neck of femur (closed)	0.000	0.912	0.088
S72.0 Fracture of neck of femur	0.000	0.958	0.042
S72.01 Fracture of neck of femur (open)	0.000	0.970	0.030
H52.1 Myopia	0.000	0.975	0.025
C79.6 Secondary malignant neoplasm of ovary	0.000	0.981	0.019
C79.8 Secondary malignant neoplasm of other specified sites	0.000	0.982	0.018
C79 Secondary malignant neoplasm of other sites	0.000	0.982	0.018
C79.2 Secondary malignant neoplasm of skin	0.000	0.983	0.017
N95.2 Postmenopausal atrophic vaginitis	0.000	0.984	0.016
C79.9 Secondary malignant neoplasm, unspecified site	0.000	0.985	0.015
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.000	0.985	0.015
T46 Poisoning by agents primarily affecting the cardiovascular system	0.014	0.986	0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.000	0.986	0.014
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.014	0.986	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.000	0.987	0.013
T36-T50 Poisoning by drugs, medicaments and biological substances	0.013	0.987	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.012	0.988	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.012	0.988	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.012	0.988	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.012	0.988	0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.000	0.988	0.011
T46.1 Calcium-channel blockers	0.011	0.988	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.011	0.989	0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.000	0.989	0.011
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.011	0.989	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.011	0.989	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.011	0.989	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.010	0.990	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.010	0.990	0.000
T46.7 Peripheral vasodilators	0.010	0.990	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.010	0.990	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.010	0.990	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.010	0.990	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.010	0.990	0.000
T39.0 Salicylates	0.010	0.990	0.000
M25.8 Other specified joint disorders	0.010	0.990	0.000
M25.86 Other specified joint disorders (Lower leg)	0.010	0.990	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.010	0.990	0.000
T38.1 Thyroid hormones and substitutes	0.010	0.990	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.010	0.990	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.010	0.990	0.000
M25.83 Other specified joint disorders (Forearm)	0.009	0.991	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.009	0.991	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.009	0.991	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.009	0.991	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.009	0.991	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.009	0.991	0.000
T50.4 Drugs affecting uric acid metabolism	0.009	0.991	0.000
T36 Poisoning by systemic antibiotics	0.009	0.991	0.000
M25.88 Other specified joint disorders (Other)	0.009	0.991	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.009	0.991	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.009	0.991	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.009	0.991	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.009	0.991	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.009	0.991	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.009	0.991	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.009	0.991	0.000
T44.0 Anticholinesterase agents	0.009	0.991	0.000
T39.1 4-Aminophenol derivatives	0.009	0.991	0.000
T43.6 Psychostimulants with abuse potential	0.009	0.991	0.000
M25.87 Other specified joint disorders (Ankle and foot)	0.009	0.991	0.000
T43.9 Psychotropic drug, unspecified	0.009	0.991	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.009	0.991	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.009	0.991	0.000
S72 Fracture of femur	0.000	0.991	0.009
T43.5 Other and unspecified antipsychotics and neuroleptics	0.009	0.991	0.000
T43.2 Other and unspecified antidepressants	0.008	0.992	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.008	0.992	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.008	0.992	0.000
T38.9 Other and unspecified hormone antagonists	0.008	0.992	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.008	0.992	0.000
T38.7 Androgens and anabolic congeners	0.008	0.992	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.008	0.992	0.000
T38.5 Other oestrogens and progestogens	0.008	0.992	0.000
T38.4 Oral contraceptives	0.008	0.992	0.000
T38.2 Antithyroid drugs	0.008	0.992	0.000
T38.0 Glucocorticoids and synthetic analogues	0.008	0.992	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.008	0.992	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.008	0.992	0.000
T39.4 Antirheumatics, not elsewhere classified	0.008	0.992	0.000
T39.2 Pyrazolone derivatives	0.008	0.992	0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.008	0.992	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.008	0.992	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.008	0.992	0.000
T50.8 Diagnostic agents	0.008	0.992	0.000
T50.7 Analeptics and opioid receptor antagonists	0.008	0.992	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.008	0.992	0.000
T50.5 Appetite depressants	0.008	0.992	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.008	0.992	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.008	0.992	0.000
T50.1 Loop [high-ceiling] diuretics	0.008	0.992	0.000
T50.0 Mineralocorticoids and their antagonists	0.008	0.992	0.000
M25.89 Other specified joint disorders (Site unspecified)	0.007	0.992	0.000
M25.82 Other specified joint disorders (Upper arm)	0.007	0.992	0.000
M25.80 Other specified joint disorders (Multiple sites)	0.007	0.992	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.007	0.993	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.007	0.993	0.000
T47.7 Emetics	0.007	0.993	0.000
T47.6 Antidiarrhoeal drugs	0.007	0.993	0.000
T47.5 Digestants	0.007	0.993	0.000
T47.4 Other laxatives	0.007	0.993	0.000
T47.3 Saline and osmotic laxatives	0.007	0.993	0.000
T47.2 Stimulant laxatives	0.007	0.993	0.000
T47.0 Histamine H(2)-receptor antagonists	0.007	0.993	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.007	0.993	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.007	0.993	0.000
T37.5 Antiviral drugs	0.007	0.993	0.000
T37.4 Anthelminthics	0.007	0.993	0.000
T37.3 Other antiprotozoal drugs	0.007	0.993	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.007	0.993	0.000
T37.1 Antimycobacterial drugs	0.007	0.993	0.000
T37.0 Sulphonamides	0.007	0.993	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.007	0.993	0.000
T41.5 Therapeutic gases	0.007	0.993	0.000
T41.4 Anaesthetic, unspecified	0.007	0.993	0.000
T41.3 Local anaesthetics	0.007	0.993	0.000
T41.2 Other and unspecified general anaesthetics	0.007	0.993	0.000
T41.1 Intravenous anaesthetics	0.007	0.993	0.000
T41.0 Inhaled anaesthetics	0.007	0.993	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.007	0.993	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.007	0.993	0.000
T48.5 Anti-common-cold drugs	0.007	0.993	0.000
T48.4 Expectorants	0.007	0.993	0.000
T48.3 Antitussives	0.007	0.993	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.007	0.993	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.007	0.993	0.000
T48.0 Oxytocic drugs	0.007	0.993	0.000
T49.9 Topical agent, unspecified	0.007	0.993	0.000
T49.8 Other topical agents	0.007	0.993	0.000
T49.7 Dental drugs, topically applied	0.007	0.993	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.007	0.993	0.000
T49.5 Ophthalmological drugs and preparations	0.007	0.993	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.007	0.993	0.000
T49.3 Emollients, demulcents and protectants	0.007	0.993	0.000
T49.2 Local astringents and local detergents	0.007	0.993	0.000
T49.1 Antipruritics	0.007	0.993	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.007	0.993	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.007	0.993	0.000
T36.9 Systemic antibiotic, unspecified	0.007	0.993	0.000
T36.8 Other systemic antibiotics	0.007	0.993	0.000
T36.7 Antifungal antibiotics, systemically used	0.007	0.993	0.000
T36.6 Rifamycins	0.007	0.993	0.000
T36.5 Aminoglycosides	0.007	0.993	0.000
T36.4 Tetracyclines	0.007	0.993	0.000
T36.3 Macrolides	0.007	0.993	0.000
T36.2 Chloramphenicol group	0.007	0.993	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.007	0.993	0.000
T36.0 Penicillins	0.006	0.993	0.000
S72.2 Subtrochanteric fracture	0.000	0.993	0.006
H52 Disorders of refraction and accommodation	0.000	0.993	0.007
S72.7 Multiple fractures of femur	0.000	0.994	0.006
S72.8 Fractures of other parts of femur	0.000	0.994	0.006
S72.3 Fracture of shaft of femur	0.000	0.994	0.006
M25 Other joint disorders, not elsewhere classified	0.006	0.994	0.000
M25.84 Other specified joint disorders (Hand)	0.006	0.994	0.000
S72.9 Fracture of femur, part unspecified	0.000	0.994	0.006
M25.6 Stiffness of joint, not elsewhere classified	0.006	0.994	0.000
T40.5 Cocaine	0.006	0.994	0.000
R10.3 Pain localised to other parts of lower abdomen	0.000	0.994	0.006
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.006	0.994	0.000
T45.5 Anticoagulants	0.005	0.994	0.000
M25.3 Other instability of joint	0.006	0.994	0.000
M25.9 Joint disorder, unspecified	0.006	0.994	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.005	0.994	0.000
T40.8 Lysergide [LSD]	0.005	0.994	0.000
T40.7 Cannabis (derivatives)	0.005	0.994	0.000
T40.3 Methadone	0.005	0.994	0.000
T40.1 Heroin	0.005	0.994	0.000
T40.0 Opium	0.005	0.994	0.000
S72.4 Fracture of lower end of femur	0.000	0.994	0.005
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.005	0.995	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.005	0.995	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.005	0.995	0.000
T45.8 Other primarily systemic and haematological agents	0.005	0.995	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.005	0.995	0.000
T45.6 Fibrinolysis-affecting drugs	0.005	0.995	0.000
T45.4 Iron and its compounds	0.005	0.995	0.000
T45.3 Enzymes, not elsewhere classified	0.005	0.995	0.000
H52.2 Astigmatism	0.000	0.995	0.005
D05.1 Intraductal carcinoma in situ	0.005	0.995	0.000
R17 Unspecified jaundice	0.005	0.995	0.000
T40.2 Other opioids	0.005	0.995	0.000
H52.7 Disorder of refraction, unspecified	0.000	0.995	0.005
M25.91 Joint disorder, unspecified (Shoulder region)	0.005	0.995	0.000
S72.20 Subtrochanteric fracture (closed)	0.000	0.995	0.005
M25.51 Pain in joint (Shoulder region)	0.005	0.995	0.000
M25.0 Haemarthrosis	0.005	0.995	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.005	0.995	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.005	0.995	0.000
M25.96 Joint disorder, unspecified (Lower leg)	0.005	0.995	0.000
M25.50 Pain in joint (Multiple sites)	0.005	0.995	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.005	0.995	0.000
S72.21 Subtrochanteric fracture (open)	0.000	0.995	0.005
H52.6 Other disorders of refraction	0.000	0.995	0.005
H52.5 Disorders of accommodation	0.000	0.995	0.005
H52.4 Presbyopia	0.000	0.995	0.005
T45.2 Vitamins, not elsewhere classified	0.005	0.995	0.000
S72.71 Multiple fractures of femur (open)	0.000	0.995	0.005
S72.70 Multiple fractures of femur (closed)	0.000	0.995	0.005
M25.5 Pain in joint	0.005	0.995	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.005	0.995	0.000
M25.31 Other instability of joint (Shoulder region)	0.005	0.995	0.000
M25.33 Other instability of joint (Forearm)	0.005	0.995	0.000
S72.81 Fractures of other parts of femur (open)	0.000	0.995	0.004
S72.1 Pertrochanteric fracture	0.000	0.995	0.005
M25.55 Pain in joint (Pelvic region and thigh)	0.005	0.995	0.000
S72.31 Fracture of shaft of femur (open)	0.000	0.995	0.004
M25.2 Flail joint	0.005	0.995	0.000
M25.1 Fistula of joint	0.005	0.995	0.000
T40.6 Other and unspecified narcotics	0.004	0.995	0.000
T40.4 Other synthetic narcotics	0.004	0.995	0.000
S72.91 Fracture of femur, part unspecified (open)	0.000	0.995	0.004
M25.37 Other instability of joint (Ankle and foot)	0.004	0.995	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.004	0.995	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.004	0.995	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.004	0.996	0.000
H34.8 Other retinal vascular occlusions	0.000	0.996	0.004
M25.34 Other instability of joint (Hand)	0.004	0.996	0.000
S72.80 Fractures of other parts of femur (closed)	0.000	0.996	0.004
T42.1 Iminostilbenes	0.004	0.996	0.000
M25.39 Other instability of joint (Site unspecified)	0.004	0.996	0.000
M25.38 Other instability of joint (Other)	0.004	0.996	0.000
M25.35 Other instability of joint (Pelvic region and thigh)	0.004	0.996	0.000
M25.32 Other instability of joint (Upper arm)	0.004	0.996	0.000
M25.30 Other instability of joint (Multiple sites)	0.004	0.996	0.000
M25.99 Joint disorder, unspecified (Site unspecified)	0.004	0.996	0.000
M25.98 Joint disorder, unspecified (Other)	0.004	0.996	0.000
M25.93 Joint disorder, unspecified (Forearm)	0.004	0.996	0.000
M25.92 Joint disorder, unspecified (Upper arm)	0.004	0.996	0.000
M25.90 Joint disorder, unspecified (Multiple sites)	0.004	0.996	0.000
S72.30 Fracture of shaft of femur (closed)	0.000	0.996	0.004
M25.06 Haemarthrosis (Lower leg)	0.004	0.996	0.000
M25.53 Pain in joint (Forearm)	0.004	0.996	0.000
M25.97 Joint disorder, unspecified (Ankle and foot)	0.004	0.996	0.000
S72.41 Fracture of lower end of femur (open)	0.000	0.996	0.004
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.004	0.996	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.004	0.996	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.004	0.996	0.000
T42.3 Barbiturates	0.004	0.996	0.000
T42.2 Succinimides and oxazolidinediones	0.004	0.996	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.004	0.996	0.000
S72.90 Fracture of femur, part unspecified (closed)	0.000	0.996	0.004
M25.58 Pain in joint (Other)	0.004	0.996	0.000
J32.9 Chronic sinusitis, unspecified	0.004	0.996	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.000	0.996	0.004
M25.94 Joint disorder, unspecified (Hand)	0.004	0.996	0.000
C50.0 Nipple and areola	0.004	0.996	0.000
M25.36 Other instability of joint (Lower leg)	0.004	0.996	0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.004	0.996	0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.000	0.996	0.004
M25.09 Haemarthrosis (Site unspecified)	0.004	0.996	0.000
M25.08 Haemarthrosis (Other)	0.004	0.996	0.000
M25.07 Haemarthrosis (Ankle and foot)	0.004	0.996	0.000
M25.05 Haemarthrosis (Pelvic region and thigh)	0.004	0.996	0.000
M25.04 Haemarthrosis (Hand)	0.004	0.996	0.000
M25.03 Haemarthrosis (Forearm)	0.004	0.996	0.000
M25.02 Haemarthrosis (Upper arm)	0.004	0.996	0.000
M25.01 Haemarthrosis (Shoulder region)	0.004	0.996	0.000
M25.00 Haemarthrosis (Multiple sites)	0.004	0.996	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.004	0.996	0.000
S02.20 Fracture of nasal bones (closed)	0.000	0.996	0.004
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.004	0.996	0.000
T42.0 Hydantoin derivatives	0.004	0.996	0.000
N28.8 Other specified disorders of kidney and ureter	0.000	0.996	0.004
H72 Perforation of tympanic membrane	0.004	0.996	0.000
S72.11 Pertrochanteric fracture (open)	0.000	0.996	0.003
M25.19 Fistula of joint (Site unspecified)	0.003	0.996	0.000
M25.18 Fistula of joint (Other)	0.003	0.996	0.000
M25.17 Fistula of joint (Ankle and foot)	0.003	0.996	0.000
M25.16 Fistula of joint (Lower leg)	0.003	0.996	0.000
M25.15 Fistula of joint (Pelvic region and thigh)	0.003	0.996	0.000
M25.14 Fistula of joint (Hand)	0.003	0.996	0.000
M25.13 Fistula of joint (Forearm)	0.003	0.996	0.000
M25.12 Fistula of joint (Upper arm)	0.003	0.996	0.000
M25.11 Fistula of joint (Shoulder region)	0.003	0.996	0.000
M25.10 Fistula of joint (Multiple sites)	0.003	0.996	0.000
M25.29 Flail joint (Site unspecified)	0.003	0.996	0.000
M25.28 Flail joint (Other)	0.003	0.996	0.000
M25.27 Flail joint (Ankle and foot)	0.003	0.996	0.000
M25.26 Flail joint (Lower leg)	0.003	0.996	0.000
M25.25 Flail joint (Pelvic region and thigh)	0.003	0.996	0.000
M25.24 Flail joint (Hand)	0.003	0.996	0.000
M25.23 Flail joint (Forearm)	0.003	0.996	0.000
M25.22 Flail joint (Upper arm)	0.003	0.996	0.000
M25.21 Flail joint (Shoulder region)	0.003	0.996	0.000
M25.20 Flail joint (Multiple sites)	0.003	0.996	0.000
M47.96 Spondylosis, unspecified (Lumbar region)	0.000	0.996	0.004
H52.3 Anisometropia and aniseikonia	0.000	0.996	0.003
T45.0 Antiallergic and antiemetic drugs	0.003	0.996	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.003	0.996	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.004	0.996	0.000
X23.9 Unspecified place	0.004	0.996	0.000
S02.2 Fracture of nasal bones	0.000	0.996	0.004
Z50.4 Psychotherapy, not elsewhere classified	0.000	0.996	0.004
S02.80 Fractures of other skull and facial bones (closed)	0.000	0.997	0.003
S02 Fracture of skull and facial bones	0.000	0.997	0.003
H72.0 Central perforation of tympanic membrane	0.003	0.997	0.000
S02.8 Fractures of other skull and facial bones	0.000	0.997	0.003
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.003	0.997	0.000
H72.8 Other perforations of tympanic membrane	0.003	0.997	0.000
S72.40 Fracture of lower end of femur (closed)	0.000	0.997	0.003
H72.1 Attic perforation of tympanic membrane	0.003	0.997	0.000
M25.52 Pain in joint (Upper arm)	0.003	0.997	0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.000	0.997	0.003
S06.5 Traumatic subdural haemorrhage	0.000	0.997	0.003
M25.54 Pain in joint (Hand)	0.003	0.997	0.000
H72.2 Other marginal perforations of tympanic membrane	0.003	0.997	0.000
S02.3 Fracture of orbital floor	0.000	0.997	0.003
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.003	0.997	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.000	0.997	0.003
Q23.1 Congenital insufficiency of aortic valve	0.003	0.997	0.000
S02.0 Fracture of vault of skull	0.000	0.997	0.003
H52.0 Hypermetropia	0.000	0.997	0.003
S02.5 Fracture of tooth	0.000	0.997	0.003
Z71.1 Person with feared complaint in whom no diagnosis is made	0.003	0.997	0.000
S02.21 Fracture of nasal bones (open)	0.000	0.997	0.003
S02.30 Fracture of orbital floor (closed)	0.000	0.997	0.003
S02.7 Multiple fractures involving skull and facial bones	0.000	0.997	0.003
S02.1 Fracture of base of skull	0.000	0.997	0.003
S02.81 Fractures of other skull and facial bones (open)	0.000	0.997	0.003
S02.4 Fracture of malar and maxillary bones	0.000	0.997	0.003
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.000	0.997	0.003
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.000	0.997	0.003
M25.4 Effusion of joint	0.003	0.997	0.000
M25.59 Pain in joint (Site unspecified)	0.002	0.997	0.000
N23 Unspecified renal colic	0.003	0.997	0.000
H35.8 Other specified retinal disorders	0.000	0.997	0.003
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters	0.000	0.997	0.003
H34.1 Central retinal artery occlusion	0.000	0.997	0.002
S02.6 Fracture of mandible	0.000	0.997	0.002
H34 Retinal vascular occlusions	0.000	0.997	0.003
S02.00 Fracture of vault of skull (closed)	0.000	0.997	0.002
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.000	0.998	0.002
S02.50 Fracture of tooth (closed)	0.000	0.998	0.002
S02.31 Fracture of orbital floor (open)	0.000	0.998	0.002
M11.26 Other chondrocalcinosis (Lower leg)	0.002	0.998	0.000
M85.65 Other cyst of bone (Pelvic region and thigh)	0.002	0.998	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.000	0.998	0.002
N20.0 Calculus of kidney	0.002	0.998	0.000
M25.43 Effusion of joint (Forearm)	0.002	0.998	0.000
S02.01 Fracture of vault of skull (open)	0.000	0.998	0.002
S92.50 Fracture of other toe (closed)	0.002	0.998	0.000
S02.51 Fracture of tooth (open)	0.000	0.998	0.002
O47.1 False labour at or after 37 completed weeks of gestation	0.002	0.998	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.002	0.998	0.000
Z39.1 Care and examination of lactating mother	0.002	0.998	0.000
S06 Intracranial injury	0.000	0.998	0.002
X23 Contact with hornets, wasps and bees	0.002	0.998	0.000
S02.71 Multiple fractures involving skull and facial bones (open)	0.000	0.998	0.002
Q23 Congenital malformations of aortic and mitral valves	0.002	0.998	0.000
S02.11 Fracture of base of skull (open)	0.000	0.998	0.002
S02.41 Fracture of malar and maxillary bones (open)	0.000	0.998	0.002
Q44.6 Cystic disease of liver	0.002	0.998	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.000	0.998	0.002
M25.44 Effusion of joint (Hand)	0.002	0.998	0.000
M25.49 Effusion of joint (Site unspecified)	0.002	0.998	0.000
M25.48 Effusion of joint (Other)	0.002	0.998	0.000
M25.41 Effusion of joint (Shoulder region)	0.002	0.998	0.000
S02.10 Fracture of base of skull (closed)	0.000	0.998	0.002
S02.40 Fracture of malar and maxillary bones (closed)	0.000	0.998	0.002
Q66 Congenital deformities of feet	0.002	0.998	0.000
S02.61 Fracture of mandible (open)	0.000	0.998	0.002
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.000	0.998	0.002
M85.6 Other cyst of bone	0.002	0.998	0.000
Q66.2 Metatarsus varus	0.002	0.998	0.000
S06.3 Focal brain injury	0.000	0.998	0.002
H34.0 Transient retinal artery occlusion	0.000	0.998	0.002
Q78 Other osteochondrodysplasias	0.002	0.998	0.000
Q74 Other congenital malformations of limb(s)	0.002	0.998	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.002	0.998	0.000
Q23.0 Congenital stenosis of aortic valve	0.002	0.998	0.000
S06.2 Diffuse brain injury	0.000	0.998	0.002
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.002	0.998	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.002	0.998	0.000
M85.68 Other cyst of bone (Other)	0.002	0.998	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.000	0.998	0.002
R09.0 Asphyxia	0.000	0.998	0.002
M25.40 Effusion of joint (Multiple sites)	0.002	0.998	0.000
Q65 Congenital deformities of hip	0.002	0.998	0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.000	0.998	0.002
T42.4 Benzodiazepines	0.002	0.998	0.000
Q76 Congenital malformations of spine and bony thorax	0.002	0.998	0.000
M25.45 Effusion of joint (Pelvic region and thigh)	0.002	0.998	0.000
M25.42 Effusion of joint (Upper arm)	0.002	0.998	0.000
Q78.0 Osteogenesis imperfecta	0.002	0.998	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.002	0.998	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.000	0.998	0.002
Q07.0 Arnold-Chiari syndrome	0.002	0.998	0.000
Q74.1 Congenital malformation of knee	0.002	0.998	0.000
X23.0 Home	0.002	0.998	0.000
D05 Carcinoma in situ of breast	0.002	0.998	0.000
Q75 Other congenital malformations of skull and face bones	0.002	0.998	0.000
Q73 Reduction defects of unspecified limb	0.002	0.998	0.000
Q72 Reduction defects of lower limb	0.002	0.998	0.000
Q71 Reduction defects of upper limb	0.002	0.998	0.000
Q70 Syndactyly	0.002	0.998	0.000
Q69 Polydactyly	0.002	0.998	0.000
Q68 Other congenital musculoskeletal deformities	0.002	0.998	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.002	0.998	0.000
Q76.1 Klippel-Feil syndrome	0.002	0.998	0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.000	0.998	0.002
S02.60 Fracture of mandible (closed)	0.000	0.998	0.002
H34.2 Other retinal artery occlusions	0.000	0.998	0.002
Q66.9 Congenital deformity of feet, unspecified	0.002	0.998	0.000
Q77.4 Achondroplasia	0.002	0.998	0.000
S06.9 Intracranial injury, unspecified	0.000	0.998	0.002
S06.7 Intracranial injury with prolonged coma	0.000	0.998	0.002
S06.4 Epidural haemorrhage	0.000	0.998	0.002
S06.1 Traumatic cerebral oedema	0.000	0.998	0.002
X23.8 Other specified place	0.002	0.998	0.000
X23.7 Farm	0.002	0.998	0.000
X23.6 Industrial and construction area	0.002	0.998	0.000
X23.5 Trade and service area	0.002	0.998	0.000
X23.4 Street and highway	0.002	0.998	0.000
X23.3 Sports and athletics area	0.002	0.998	0.000
X23.2 School, other institution and public administrative area	0.002	0.998	0.000
X23.1 Residential institution	0.002	0.998	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.002	0.998	0.000
H34.9 Retinal vascular occlusion, unspecified	0.000	0.998	0.002
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.002	0.998	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.002	0.998	0.000
Q23.4 Hypoplastic left heart syndrome	0.002	0.998	0.000
Q23.3 Congenital mitral insufficiency	0.002	0.998	0.000
Q23.2 Congenital mitral stenosis	0.002	0.998	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.998	0.002
S06.0 Concussion	0.000	0.998	0.002
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.002	0.998	0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.002	0.998	0.000
M85.66 Other cyst of bone (Lower leg)	0.002	0.998	0.000
Q54.9 Hypospadias, unspecified	0.000	0.998	0.002
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.002	0.998	0.000
S72.10 Pertrochanteric fracture (closed)	0.000	0.998	0.002
C32.1 Supraglottis	0.000	0.998	0.002
M24.8 Other specific joint derangements, not elsewhere classified	0.002	0.998	0.000
W29.9 Unspecified place	0.000	0.998	0.002
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm	0.002	0.998	0.000
M85.67 Other cyst of bone (Ankle and foot)	0.002	0.998	0.000
Q66.6 Other congenital valgus deformities of feet	0.002	0.998	0.000
Q66.5 Congenital pes planus	0.002	0.998	0.000
Q66.4 Talipes calcaneovalgus	0.002	0.998	0.000
Q66.1 Talipes calcaneovarus	0.002	0.998	0.000
Q66.0 Talipes equinovarus	0.002	0.998	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.000	0.998	0.002
Q65.8 Other congenital deformities of hip	0.002	0.998	0.000
M85.69 Other cyst of bone (Site unspecified)	0.002	0.998	0.000
M85.64 Other cyst of bone (Hand)	0.002	0.998	0.000
M85.63 Other cyst of bone (Forearm)	0.002	0.998	0.000
M85.62 Other cyst of bone (Upper arm)	0.002	0.998	0.000
M85.61 Other cyst of bone (Shoulder region)	0.002	0.998	0.000
M85.60 Other cyst of bone (Multiple sites)	0.002	0.998	0.000
Q66.7 Pes cavus	0.002	0.998	0.000
Q67.5 Congenital deformity of spine	0.002	0.998	0.000
Q74.9 Unspecified congenital malformation of limb(s)	0.002	0.998	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.002	0.998	0.000
Q74.3 Arthrogryposis multiplex congenita	0.002	0.998	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.002	0.998	0.000
Q78.9 Osteochondrodysplasia, unspecified	0.002	0.998	0.000
Q78.8 Other specified osteochondrodysplasias	0.002	0.998	0.000
Q78.6 Multiple congenital exostoses	0.002	0.998	0.000
Q78.5 Metaphyseal dysplasia	0.002	0.998	0.000
Q78.4 Enchondromatosis	0.002	0.998	0.000
Q78.3 Progressive diaphyseal dysplasia	0.002	0.998	0.000
Q78.2 Osteopetrosis	0.002	0.998	0.000
Q78.1 Polyostotic fibrous dysplasia	0.002	0.998	0.000
Q66.8 Other congenital deformities of feet	0.002	0.998	0.000
Q67.8 Other congenital deformities of chest	0.002	0.998	0.000
Q67.7 Pectus carinatum	0.002	0.998	0.000
Q67.6 Pectus excavatum	0.002	0.998	0.000
Q67.3 Plagiocephaly	0.002	0.998	0.000
Q67.2 Dolichocephaly	0.002	0.998	0.000
Q67.1 Compression facies	0.002	0.998	0.000
Q67.0 Facial asymmetry	0.002	0.998	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.000	0.998	0.002
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.002	0.998	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.002	0.998	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.002	0.998	0.000
Q77.6 Chondroectodermal dysplasia	0.002	0.998	0.000
Q77.5 Diastrophic dysplasia	0.002	0.998	0.000
Q77.3 Chondrodysplasia punctata	0.002	0.998	0.000
Q77.2 Short rib syndrome	0.002	0.998	0.000
Q77.1 Thanatophoric short stature	0.002	0.998	0.000
Q77.0 Achondrogenesis	0.002	0.998	0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.000	0.998	0.002
Q07 Other congenital malformations of nervous system	0.002	0.998	0.000
J32.2 Chronic ethmoidal sinusitis	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations