TreeWAS – Variant ID: rs12799264

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I50.0 Congestive heart failure	0.238	0.762	0.000
I30-I52 Other forms of heart disease	0.237	0.763	0.000
I51 Complications and ill-defined descriptions of heart disease	0.232	0.768	0.000
I49 Other cardiac arrhythmias	0.232	0.768	0.000
I50 Heart failure	0.230	0.770	0.000
I31 Other diseases of pericardium	0.229	0.771	0.000
I42 Cardiomyopathy	0.220	0.780	0.000
I51.7 Cardiomegaly	0.219	0.781	0.000
I31.3 Pericardial effusion (noninflammatory)	0.216	0.784	0.000
I51.9 Heart disease, unspecified	0.216	0.784	0.000
I49.8 Other specified cardiac arrhythmias	0.215	0.785	0.000
I36 Nonrheumatic tricuspid valve disorders	0.210	0.790	0.000
I49.4 Other and unspecified premature depolarisation	0.206	0.794	0.000
I42.2 Other hypertrophic cardiomyopathy	0.203	0.797	0.000
I49.0 Ventricular fibrillation and flutter	0.200	0.800	0.000
I31.9 Disease of pericardium, unspecified	0.196	0.804	0.000
I46 Cardiac arrest	0.194	0.806	0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.192	0.808	0.000
I30 Acute pericarditis	0.190	0.810	0.000
I37 Pulmonary valve disorders	0.190	0.810	0.000
I49.1 Atrial premature depolarisation	0.183	0.817	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.182	0.818	0.000
I51.0 Cardiac septal defect, acquired	0.181	0.819	0.000
I49.5 Sick sinus syndrome	0.179	0.821	0.000
I42.9 Cardiomyopathy, unspecified	0.176	0.824	0.000
I46.0 Cardiac arrest with successful resuscitation	0.176	0.824	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.175	0.825	0.000
I38 Endocarditis, valve unspecified	0.174	0.826	0.000
I51.4 Myocarditis, unspecified	0.171	0.829	0.000
I52 Other heart disorders in diseases classified elsewhere	0.170	0.830	0.000
I48 Atrial fibrillation and flutter	0.170	0.830	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.170	0.830	0.000
I41 Myocarditis in diseases classified elsewhere	0.170	0.830	0.000
I40 Acute myocarditis	0.170	0.830	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.170	0.830	0.000
I32 Pericarditis in diseases classified elsewhere	0.170	0.830	0.000
I51.5 Myocardial degeneration	0.166	0.834	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.166	0.834	0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.166	0.834	0.000
I30.9 Acute pericarditis, unspecified	0.166	0.834	0.000
I49.2 Junctional premature depolarisation	0.166	0.834	0.000
I31.8 Other specified diseases of pericardium	0.164	0.836	0.000
I31.2 Haemopericardium, not elsewhere classified	0.164	0.836	0.000
I31.1 Chronic constrictive pericarditis	0.164	0.836	0.000
I31.0 Chronic adhesive pericarditis	0.164	0.836	0.000
I42.8 Other cardiomyopathies	0.159	0.841	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.158	0.842	0.000
I42.5 Other restrictive cardiomyopathy	0.158	0.842	0.000
I42.4 Endocardial fibroelastosis	0.158	0.842	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.158	0.842	0.000
I49.9 Cardiac arrhythmia, unspecified	0.157	0.843	0.000
I37.1 Pulmonary valve insufficiency	0.156	0.844	0.000
I33 Acute and subacute endocarditis	0.156	0.844	0.000
I42.0 Dilated cardiomyopathy	0.156	0.844	0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.151	0.849	0.000
I36.8 Other nonrheumatic tricuspid valve disorders	0.151	0.849	0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.151	0.849	0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.151	0.849	0.000
I46.1 Sudden cardiac death, so described	0.139	0.861	0.000
I30.8 Other forms of acute pericarditis	0.136	0.864	0.000
I30.0 Acute nonspecific idiopathic pericarditis	0.136	0.864	0.000
I37.9 Pulmonary valve disorder, unspecified	0.136	0.864	0.000
I37.8 Other pulmonary valve disorders	0.136	0.864	0.000
I37.2 Pulmonary valve stenosis with insufficiency	0.136	0.864	0.000
I37.0 Pulmonary valve stenosis	0.136	0.864	0.000
I42.6 Alcoholic cardiomyopathy	0.136	0.864	0.000
I51.6 Cardiovascular disease, unspecified	0.133	0.867	0.000
I51.8 Other ill-defined heart diseases	0.125	0.875	0.000
I32.8 Pericarditis in other diseases classified elsewhere	0.122	0.878	0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.122	0.878	0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.122	0.878	0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.122	0.878	0.000
I39.4 Multiple valve disorders in diseases classified elsewhere	0.122	0.878	0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.122	0.878	0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.122	0.878	0.000
I39.1 Aortic valve disorders in diseases classified elsewhere	0.122	0.878	0.000
I39.0 Mitral valve disorders in diseases classified elsewhere	0.122	0.878	0.000
I40.9 Acute myocarditis, unspecified	0.122	0.878	0.000
I40.8 Other acute myocarditis	0.122	0.878	0.000
I40.1 Isolated myocarditis	0.122	0.878	0.000
I40.0 Infective myocarditis	0.122	0.878	0.000
I41.8 Myocarditis in other diseases classified elsewhere	0.122	0.878	0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.122	0.878	0.000
I41.1 Myocarditis in viral diseases classified elsewhere	0.122	0.878	0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.122	0.878	0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.122	0.878	0.000
I43.2 Cardiomyopathy in nutritional diseases	0.122	0.878	0.000
I43.1 Cardiomyopathy in metabolic diseases	0.122	0.878	0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.122	0.878	0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.122	0.878	0.000
I48.4 Atypical atrial flutter	0.122	0.878	0.000
I48.3 Typical atrial flutter	0.122	0.878	0.000
I48.2 Chronic atrial fibrillation	0.122	0.878	0.000
I48.1 Persistent atrial fibrillation	0.122	0.878	0.000
I48.0 Paroxysmal atrial fibrillation	0.122	0.878	0.000
I52.8 Other heart disorders in other diseases classified elsewhere	0.122	0.878	0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.122	0.878	0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.122	0.878	0.000
I30.1 Infective pericarditis	0.114	0.886	0.000
I33.9 Acute endocarditis, unspecified	0.112	0.888	0.000
I46.9 Cardiac arrest, unspecified	0.100	0.900	0.000
I33.0 Acute and subacute infective endocarditis	0.098	0.902	0.000
I35 Nonrheumatic aortic valve disorders	0.098	0.902	0.000
I49.3 Ventricular premature depolarisation	0.092	0.908	0.000
I50.1 Left ventricular failure	0.092	0.908	0.000
I35.8 Other aortic valve disorders	0.084	0.916	0.000
I47 Paroxysmal tachycardia	0.078	0.922	0.000
I34 Nonrheumatic mitral valve disorders	0.065	0.935	0.000
I50.9 Heart failure, unspecified	0.064	0.936	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.059	0.941	0.000
I45 Other conduction disorders	0.057	0.943	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.054	0.945	0.000
I47.0 Reentry ventricular arrhythmia	0.054	0.946	0.000
I35.1 Aortic (valve) insufficiency	0.053	0.947	0.000
I35.0 Aortic (valve) stenosis	0.050	0.950	0.000
I47.2 Ventricular tachycardia	0.050	0.950	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.049	0.950	0.000
I35.9 Aortic valve disorder, unspecified	0.049	0.951	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.046	0.953	0.000
I63 Cerebral infarction	0.046	0.954	0.000
Chapter IX Diseases of the circulatory system	0.045	0.955	0.000
I45.2 Bifascicular block	0.044	0.955	0.000
I44 Atrioventricular and left bundle-branch block	0.044	0.956	0.000
I60-I69 Cerebrovascular diseases	0.044	0.956	0.000
I63.9 Cerebral infarction, unspecified	0.044	0.956	0.000
I65.2 Occlusion and stenosis of carotid artery	0.043	0.957	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.043	0.957	0.000
I45.4 Nonspecific intraventricular block	0.043	0.957	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.042	0.958	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.041	0.958	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.041	0.959	0.000
I45.0 Right fascicular block	0.041	0.959	0.000
I12 Hypertensive renal disease	0.041	0.959	0.000
I12.9 Hypertensive renal disease without renal failure	0.040	0.960	0.000
I05-I09 Chronic rheumatic heart diseases	0.040	0.960	0.000
I10-I15 Hypertensive diseases	0.039	0.961	0.000
I12.0 Hypertensive renal disease with renal failure	0.038	0.962	0.000
I45.6 Preexcitation syndrome	0.037	0.963	0.000
I62 Other nontraumatic intracranial haemorrhage	0.037	0.963	0.000
I45.3 Trifascicular block	0.037	0.963	0.000
I07 Rheumatic tricuspid valve diseases	0.036	0.964	0.000
I45.5 Other specified heart block	0.034	0.965	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.034	0.966	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.034	0.966	0.000
I07.1 Tricuspid insufficiency	0.034	0.966	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.033	0.967	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.033	0.967	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.033	0.967	0.000
I00-I02 Acute rheumatic fever	0.033	0.967	0.000
I45.9 Conduction disorder, unspecified	0.032	0.967	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.032	0.968	0.000
I44.5 Left posterior fascicular block	0.032	0.968	0.000
I44.4 Left anterior fascicular block	0.032	0.968	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.031	0.968	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.031	0.968	0.000
I45.8 Other specified conduction disorders	0.031	0.969	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.031	0.969	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.031	0.969	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.031	0.969	0.000
I65.1 Occlusion and stenosis of basilar artery	0.031	0.969	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.031	0.969	0.000
I08 Multiple valve diseases	0.031	0.969	0.000
I44.3 Other and unspecified atrioventricular block	0.031	0.969	0.000
I61 Intracerebral haemorrhage	0.031	0.969	0.000
I44.1 Atrioventricular block, second degree	0.031	0.969	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.031	0.969	0.000
I44.6 Other and unspecified fascicular block	0.029	0.971	0.000
I99 Other and unspecified disorders of circulatory system	0.029	0.971	0.000
I06 Rheumatic aortic valve diseases	0.029	0.971	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.029	0.971	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.028	0.972	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.028	0.972	0.000
I13 Hypertensive heart and renal disease	0.028	0.972	0.000
I09 Other rheumatic heart diseases	0.028	0.972	0.000
I05 Rheumatic mitral valve diseases	0.027	0.973	0.000
I62.1 Nontraumatic extradural haemorrhage	0.027	0.973	0.000
I07.9 Tricuspid valve disease, unspecified	0.026	0.974	0.000
I07.8 Other tricuspid valve diseases	0.026	0.974	0.000
I07.2 Tricuspid stenosis with insufficiency	0.026	0.974	0.000
I07.0 Tricuspid stenosis	0.026	0.974	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.025	0.974	0.000
I44.0 Atrioventricular block, first degree	0.025	0.975	0.000
I63.8 Other cerebral infarction	0.025	0.975	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.025	0.975	0.000
I44.2 Atrioventricular block, complete	0.025	0.975	0.000
I61.8 Other intracerebral haemorrhage	0.024	0.976	0.000
I15 Secondary hypertension	0.024	0.976	0.000
I02 Rheumatic chorea	0.023	0.976	0.000
I01 Rheumatic fever with heart involvement	0.023	0.976	0.000
I00 Rheumatic fever without mention of heart involvement	0.023	0.976	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.023	0.977	0.000
I08.0 Disorders of both mitral and aortic valves	0.023	0.977	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.023	0.977	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.023	0.977	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.023	0.977	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.023	0.977	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.023	0.977	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.023	0.977	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.023	0.977	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.023	0.977	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.023	0.977	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.023	0.977	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.023	0.977	0.000
I68.0 Cerebral amyloid angiopathy	0.023	0.977	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.023	0.977	0.000
I11 Hypertensive heart disease	0.022	0.977	0.000
I08.9 Multiple valve disease, unspecified	0.022	0.977	0.000
S00 Superficial injury of head	0.023	0.977	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.022	0.978	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.022	0.978	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.022	0.978	0.000
S00.0 Superficial injury of scalp	0.022	0.978	0.000
S00.9 Superficial injury of head, part unspecified	0.022	0.978	0.000
S00.8 Superficial injury of other parts of head	0.022	0.978	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.021	0.979	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.021	0.979	0.000
I06.8 Other rheumatic aortic valve diseases	0.021	0.979	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.021	0.979	0.000
I06.1 Rheumatic aortic insufficiency	0.021	0.979	0.000
I06.0 Rheumatic aortic stenosis	0.021	0.979	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.020	0.979	0.000
I97.0 Postcardiotomy syndrome	0.020	0.979	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.020	0.980	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.020	0.980	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.020	0.980	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.020	0.980	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.020	0.980	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.020	0.980	0.000
I09.8 Other specified rheumatic heart diseases	0.020	0.980	0.000
I09.2 Chronic rheumatic pericarditis	0.020	0.980	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.020	0.980	0.000
I09.0 Rheumatic myocarditis	0.020	0.980	0.000
I05.0 Mitral stenosis	0.020	0.980	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.020	0.980	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.020	0.980	0.000
I97.1 Other functional disturbances following cardiac surgery	0.020	0.980	0.000
I05.8 Other mitral valve diseases	0.020	0.980	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.020	0.980	0.000
I05.9 Mitral valve disease, unspecified	0.019	0.981	0.000
S00.7 Multiple superficial injuries of head	0.019	0.981	0.000
I09.9 Rheumatic heart disease, unspecified	0.019	0.981	0.000
I05.2 Mitral stenosis with insufficiency	0.019	0.981	0.000
I05.1 Rheumatic mitral insufficiency	0.019	0.981	0.000
I45.1 Other and unspecified right bundle-branch block	0.019	0.981	0.000
S00.4 Superficial injury of ear	0.018	0.982	0.000
I08.8 Other multiple valve diseases	0.018	0.982	0.000
I60 Subarachnoid haemorrhage	0.018	0.982	0.000
I15.9 Seconday hypertension, unspecified	0.017	0.982	0.000
I15.8 Other secondary hypertension	0.017	0.982	0.000
I15.2 Hypertension secondary to endocrine disorders	0.017	0.982	0.000
I15.0 Renovascular hypertension	0.017	0.982	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.017	0.983	0.000
I01.8 Other acute rheumatic heart disease	0.017	0.983	0.000
I01.2 Acute rheumatic myocarditis	0.017	0.983	0.000
I01.1 Acute rheumatic endocarditis	0.017	0.983	0.000
I01.0 Acute rheumatic pericarditis	0.017	0.983	0.000
I02.9 Rheumatic chorea without heart involvement	0.017	0.983	0.000
I02.0 Rheumatic chorea with heart involvement	0.017	0.983	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.016	0.983	0.000
I28 Other diseases of pulmonary vessels	0.016	0.983	0.000
I95 Hypotension	0.017	0.983	0.000
I47.1 Supraventricular tachycardia	0.016	0.984	0.000
S00.3 Superficial injury of nose	0.015	0.984	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.015	0.985	0.000
I95.1 Orthostatic hypotension	0.015	0.985	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.014	0.986	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.014	0.986	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.014	0.986	0.000
I98.0 Cardiovascular syphilis	0.014	0.986	0.000
I26 Pulmonary embolism	0.014	0.986	0.000
S00.2 Other superficial injuries of eyelid and periocular area	0.014	0.986	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.014	0.986	0.000
S01.5 Open wound of lip and oral cavity	0.014	0.986	0.000
I15.1 Hypertension secondary to other renal disorders	0.014	0.986	0.000
S00.1 Contusion of eyelid and periocular area	0.014	0.986	0.000
S01 Open wound of head	0.014	0.986	0.000
I69 Sequelae of cerebrovascular disease	0.013	0.987	0.000
S00-S09 Injuries to the head	0.013	0.987	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.013	0.987	0.000
S01.2 Open wound of nose	0.013	0.987	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.013	0.987	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.013	0.987	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.013	0.987	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.013	0.987	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.013	0.987	0.000
N31.8 Other neuromuscular dysfunction of bladder	0.000	0.987	0.013
I95.8 Other hypotension	0.013	0.987	0.000
S00.5 Superficial injury of lip and oral cavity	0.013	0.987	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.013	0.987	0.000
I95.0 Idiopathic hypotension	0.012	0.987	0.000
F10.0 Acute intoxication	0.013	0.987	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.012	0.988	0.000
I28.8 Other specified diseases of pulmonary vessels	0.012	0.988	0.000
I28.1 Aneurysm of pulmonary artery	0.012	0.988	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.012	0.988	0.000
I34.1 Mitral (valve) prolapse	0.011	0.988	0.001
S06 Intracranial injury	0.012	0.988	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.011	0.989	0.000
I60.8 Other subarachnoid haemorrhage	0.010	0.989	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.010	0.989	0.000
I27 Other pulmonary heart diseases	0.011	0.989	0.000
S01.0 Open wound of scalp	0.011	0.989	0.000
S01.8 Open wound of other parts of head	0.011	0.989	0.000
S06.5 Traumatic subdural haemorrhage	0.010	0.990	0.000
S01.7 Multiple open wounds of head	0.010	0.990	0.000
S01.1 Open wound of eyelid and periocular area	0.010	0.990	0.000
S01.3 Open wound of ear	0.010	0.990	0.000
I69.3 Sequelae of cerebral infarction	0.010	0.990	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.010	0.990	0.000
S08 Traumatic amputation of part of head	0.010	0.990	0.000
S07 Crushing injury of head	0.010	0.990	0.000
S04 Injury of cranial nerves	0.010	0.990	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.010	0.990	0.000
S06.2 Diffuse brain injury	0.010	0.990	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.009	0.990	0.000
S06.0 Concussion	0.009	0.990	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.009	0.991	0.000
S01.4 Open wound of cheek and temporomandibular area	0.009	0.991	0.000
S05 Injury of eye and orbit	0.009	0.991	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.009	0.991	0.000
S06.7 Intracranial injury with prolonged coma	0.009	0.991	0.000
S06.3 Focal brain injury	0.009	0.991	0.000
S06.1 Traumatic cerebral oedema	0.009	0.991	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.008	0.991	0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.008	0.992	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.008	0.992	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.008	0.992	0.000
S06.9 Intracranial injury, unspecified	0.008	0.992	0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.992	0.008
S06.4 Epidural haemorrhage	0.008	0.992	0.000
S06.8 Other intracranial injuries	0.008	0.992	0.000
I27.8 Other specified pulmonary heart diseases	0.008	0.992	0.000
S06.00 Concussion (without open intracranial wound)	0.008	0.992	0.000
I27.1 Kyphoscoliotic heart disease	0.008	0.992	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.008	0.992	0.000
I34.0 Mitral (valve) insufficiency	0.007	0.992	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.007	0.993	0.000
S05.9 Injury of eye and orbit, part unspecified	0.007	0.993	0.000
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head	0.007	0.993	0.000
S03.4 Sprain and strain of jaw	0.007	0.993	0.000
S03.3 Dislocation of other and unspecified parts of head	0.007	0.993	0.000
S03.2 Dislocation of tooth	0.007	0.993	0.000
S03.1 Dislocation of septal cartilage of nose	0.007	0.993	0.000
S03.0 Dislocation of jaw	0.007	0.993	0.000
S04.9 Injury of unspecified cranial nerve	0.007	0.993	0.000
S04.8 Injury of other cranial nerves	0.007	0.993	0.000
S04.7 Injury of accessory nerve	0.007	0.993	0.000
S04.6 Injury of acoustic nerve	0.007	0.993	0.000
S04.5 Injury of facial nerve	0.007	0.993	0.000
S04.4 Injury of abducent nerve	0.007	0.993	0.000
S04.3 Injury of trigeminal nerve	0.007	0.993	0.000
S04.2 Injury of trochlear nerve	0.007	0.993	0.000
S04.1 Injury of oculomotor nerve	0.007	0.993	0.000
S04.0 Injury of optic nerve and pathways	0.007	0.993	0.000
S07.9 Crushing injury of head, part unspecified	0.007	0.993	0.000
S07.8 Crushing injury of other parts of head	0.007	0.993	0.000
S07.1 Crushing injury of skull	0.007	0.993	0.000
S07.0 Crushing injury of face	0.007	0.993	0.000
S08.9 Traumatic amputation of unspecified part of head	0.007	0.993	0.000
S08.8 Traumatic amputation of other parts of head	0.007	0.993	0.000
S08.1 Traumatic amputation of ear	0.007	0.993	0.000
S08.0 Avulsion of scalp	0.007	0.993	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.007	0.993	0.000
S06.01 Concussion (with open intracranial wound)	0.007	0.993	0.000
I67 Other cerebrovascular diseases	0.007	0.993	0.000
S05.7 Avulsion of eye	0.007	0.993	0.000
S05.6 Penetrating wound of eyeball without foreign body	0.007	0.993	0.000
S05.5 Penetrating wound of eyeball with foreign body	0.007	0.993	0.000
S05.4 Penetrating wound of orbit with or without foreign body	0.007	0.993	0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.007	0.993	0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.007	0.993	0.000
I27.2 Other secondary pulmonary hypertension	0.007	0.993	0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.007	0.993	0.000
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.006	0.993	0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.006	0.993	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.006	0.993	0.000
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.006	0.993	0.000
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.006	0.993	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.006	0.993	0.000
S01.9 Open wound of head, part unspecified	0.006	0.994	0.000
S05.8 Other injuries of eye and orbit	0.006	0.994	0.000
I27.9 Pulmonary heart disease, unspecified	0.006	0.994	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.006	0.994	0.000
S05.1 Contusion of eyeball and orbital tissues	0.006	0.994	0.000
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.006	0.994	0.000
S06.41 Epidural haemorrhage (with open intracranial wound)	0.006	0.994	0.000
S06.81 Other intracranial injuries (with open intracranial wound)	0.006	0.994	0.000
I27.0 Primary pulmonary hypertension	0.006	0.994	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.006	0.994	0.000
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.006	0.994	0.000
I95.2 Hypotension due to drugs	0.005	0.994	0.001
S06.40 Epidural haemorrhage (without open intracranial wound)	0.005	0.994	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.005	0.994	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.005	0.994	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.005	0.995	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.005	0.995	0.000
I67.5 Moyamoya disease	0.005	0.995	0.000
I67.4 Hypertensive encephalopathy	0.005	0.995	0.000
I67.3 Progressive vascular leukoencephalopathy	0.005	0.995	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.005	0.995	0.000
S09 Other and unspecified injuries of head	0.005	0.995	0.000
I44.7 Left bundle-branch block, unspecified	0.005	0.995	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.004	0.996	0.000
F10 Mental and behavioural disorders due to use of alcohol	0.004	0.996	0.000
R25.2 Cramp and spasm	0.000	0.996	0.004
S02 Fracture of skull and facial bones	0.004	0.996	0.000
I67.1 Cerebral aneurysm, nonruptured	0.004	0.996	0.000
L98.8 Other specified disorders of skin and subcutaneous tissue	0.004	0.996	0.000
F10.4 Withdrawal state with delirium	0.004	0.996	0.000
S09.7 Multiple injuries of head	0.004	0.996	0.000
S09.2 Traumatic rupture of ear drum	0.004	0.996	0.000
S09.1 Injury of muscle and tendon of head	0.004	0.996	0.000
S09.0 Injury of blood vessels of head, not elsewhere classified	0.004	0.996	0.000
R25 Abnormal involuntary movements	0.000	0.996	0.004
Z09.8 Follow-up examination after other treatment for other conditions	0.000	0.996	0.004
K42.0 Umbilical hernia with obstruction, without gangrene	0.004	0.996	0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.996	0.004
R25.1 Tremor, unspecified	0.000	0.996	0.004
R25.8 Other and unspecified abnormal involuntary movements	0.000	0.996	0.004
F10.5 Psychotic disorder	0.004	0.996	0.000
F10.3 Withdrawal state	0.004	0.996	0.000
I67.2 Cerebral atherosclerosis	0.003	0.996	0.000
I67.8 Other specified cerebrovascular diseases	0.004	0.996	0.000
S02.2 Fracture of nasal bones	0.003	0.996	0.000
S09.8 Other specified injuries of head	0.003	0.996	0.000
F10.8 Other mental and behavioural disorders	0.003	0.997	0.000
F10.7 Residual and late-onset psychotic disorder	0.003	0.997	0.000
F10.6 Amnesic syndrome	0.003	0.997	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.003	0.997	0.000
S02.7 Multiple fractures involving skull and facial bones	0.003	0.997	0.000
F10.9 Unspecified mental and behavioural disorder	0.003	0.997	0.000
S02.6 Fracture of mandible	0.003	0.997	0.000
S02.0 Fracture of vault of skull	0.003	0.997	0.000
R25.0 Abnormal head movements	0.000	0.997	0.003
R29.4 Clicking hip	0.000	0.997	0.003
R29.3 Abnormal posture	0.000	0.997	0.003
R29.2 Abnormal reflex	0.000	0.997	0.003
R29.1 Meningismus	0.000	0.997	0.003
R29.0 Tetany	0.000	0.997	0.003
S02.8 Fractures of other skull and facial bones	0.003	0.997	0.000
S02.1 Fracture of base of skull	0.003	0.997	0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.000	0.997	0.003
S02.5 Fracture of tooth	0.003	0.997	0.000
S02.3 Fracture of orbital floor	0.002	0.997	0.001
S02.20 Fracture of nasal bones (closed)	0.003	0.997	0.000
M66.24 Spontaneous rupture of extensor tendons (Hand)	0.003	0.997	0.000
B34.9 Viral infection, unspecified	0.000	0.997	0.003
S02.21 Fracture of nasal bones (open)	0.003	0.997	0.000
F17.2 Dependence syndrome	0.003	0.997	0.000
R25.3 Fasciculation	0.000	0.997	0.003
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.003	0.997	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.002	0.997	0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.997	0.003
S02.71 Multiple fractures involving skull and facial bones (open)	0.002	0.997	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.002	0.997	0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.000	0.997	0.003
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.003	0.997	0.000
S02.61 Fracture of mandible (open)	0.002	0.997	0.000
S02.4 Fracture of malar and maxillary bones	0.002	0.997	0.001
C69.3 Choroid	0.003	0.997	0.000
S02.01 Fracture of vault of skull (open)	0.002	0.997	0.000
M25.46 Effusion of joint (Lower leg)	0.003	0.997	0.000
S02.60 Fracture of mandible (closed)	0.002	0.997	0.000
O73.0 Retained placenta, without haemorrhage	0.003	0.997	0.000
Z09.0 Follow-up examination after surgery for other conditions	0.000	0.997	0.003
H92.0 Otalgia	0.000	0.997	0.002
S02.81 Fractures of other skull and facial bones (open)	0.002	0.998	0.000
S02.11 Fracture of base of skull (open)	0.002	0.998	0.000
S02.51 Fracture of tooth (open)	0.002	0.998	0.000
F11 Mental and behavioural disorders due to use of opioids	0.002	0.998	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.002	0.998	0.000
S02.31 Fracture of orbital floor (open)	0.002	0.998	0.001
S02.00 Fracture of vault of skull (closed)	0.002	0.998	0.000
M66.2 Spontaneous rupture of extensor tendons	0.002	0.998	0.000
F11.2 Dependence syndrome	0.002	0.998	0.000
F12 Mental and behavioural disorders due to use of cannabinoids	0.002	0.998	0.000
E28.2 Polycystic ovarian syndrome	0.000	0.998	0.002
K12.3 Oral mucositis (ulcerative)	0.002	0.998	0.000
R27 Other lack of coordination	0.000	0.998	0.002
N31.1 Reflex neuropathic bladder, not elsewhere classified	0.000	0.998	0.002
N31.0 Uninhibited neuropathic bladder, not elsewhere classified	0.000	0.998	0.002
F18 Mental and behavioural disorders due to use of volatile solvents	0.002	0.998	0.000
F16 Mental and behavioural disorders due to use of hallucinogens	0.002	0.998	0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.002	0.998	0.000
F14 Mental and behavioural disorders due to use of cocaine	0.002	0.998	0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.002	0.998	0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms	0.000	0.998	0.002
F17 Mental and behavioural disorders due to use of tobacco	0.002	0.998	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.002	0.998	0.001
I78.1 Naevus, nonneoplastic	0.000	0.998	0.002
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.002	0.998	0.000
Z09.2 Follow-up examination after chemotherapy for other conditions	0.000	0.998	0.002
S02.80 Fractures of other skull and facial bones (closed)	0.002	0.998	0.000
S02.30 Fracture of orbital floor (closed)	0.001	0.998	0.001
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.002	0.998	0.000
R27.0 Ataxia, unspecified	0.000	0.998	0.002
F11.9 Unspecified mental and behavioural disorder	0.002	0.998	0.000
F11.8 Other mental and behavioural disorders	0.002	0.998	0.000
F11.7 Residual and late-onset psychotic disorder	0.002	0.998	0.000
F11.6 Amnesic syndrome	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations