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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12814941
log Bayes Factor = 12.4883
Chromosome 12   position 106,408,172  (GRCh37) Explore rs12814941 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.997 0.003 0.000
Chapter XXI Factors influencing health status and contact with health services
0.997 0.003 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.996 0.004 0.000
Chapter I Certain infectious and parasitic diseases
0.993 0.007 0.000
D69 Purpura and other haemorrhagic conditions
0.993 0.007 0.000
Chapter XX External causes of morbidity and mortality
0.992 0.008 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.989 0.011 0.000
Z50 Care involving use of rehabilitation procedures
0.988 0.012 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.985 0.015 0.000
S00-S09 Injuries to the head
0.983 0.017 0.000
Chapter VI Diseases of the nervous system
0.980 0.020 0.000
A00-A09 Intestinal infectious diseases
0.980 0.020 0.000
W00-W19 Falls
0.979 0.021 0.000
Z50.1 Other physical therapy
0.971 0.029 0.000
W19 Unspecified fall
0.968 0.032 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.963 0.037 0.000
Chapter X Diseases of the respiratory system
0.963 0.037 0.000
S01 Open wound of head
0.963 0.037 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.962 0.038 0.000
Z51 Other medical care
0.959 0.041 0.000
Chapter II Neoplasms
0.956 0.044 0.000
M45-M49 Spondylopathies
0.954 0.046 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.953 0.047 0.000
D69.6 Thrombocytopenia, unspecified
0.952 0.048 0.000
Z51.2 Other chemotherapy
0.949 0.051 0.000
D80-D89 Certain disorders involving the immune mechanism
0.948 0.052 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.943 0.057 0.000
W19.9 Unspecified place
0.943 0.057 0.000
Chapter IX Diseases of the circulatory system
0.940 0.060 0.000
Chapter XXII Codes for special purposes
0.926 0.074 0.000
I60-I69 Cerebrovascular diseases
0.925 0.075 0.000
S01.8 Open wound of other parts of head
0.922 0.078 0.000
D00-D09 In situ neoplasms
0.921 0.079 0.000
M47 Spondylosis
0.917 0.083 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.916 0.084 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.916 0.084 0.000
E70-E90 Metabolic disorders
0.914 0.086 0.000
Z42 Follow-up care involving plastic surgery
0.908 0.092 0.000
J00-J06 Acute upper respiratory infections
0.907 0.093 0.000
M80-M85 Disorders of bone density and structure
0.907 0.093 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.903 0.097 0.000
S00 Superficial injury of head
0.900 0.100 0.000
J30-J39 Other diseases of upper respiratory tract
0.899 0.101 0.000
G70-G73 Diseases of myoneural junction and muscle
0.898 0.102 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.898 0.102 0.000
D05 Carcinoma in situ of breast
0.898 0.102 0.000
E87.6 Hypokalaemia
0.893 0.107 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.891 0.109 0.000
A30-A49 Other bacterial diseases
0.889 0.111 0.000
Z45 Adjustment and management of implanted device
0.882 0.118 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.880 0.120 0.000
E10-E14 Diabetes mellitus
0.874 0.126 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.872 0.128 0.000
M65-M68 Disorders of synovium and tendon
0.867 0.133 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.866 0.134 0.000
D68 Other coagulation defects
0.864 0.136 0.000
G20-G26 Extrapyramidal and movement disorders
0.864 0.136 0.000
J95-J99 Other diseases of the respiratory system
0.862 0.138 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.861 0.139 0.000
B95-B98 Bacterial, viral and other infectious agents
0.858 0.142 0.000
S80-S89 Injuries to the knee and lower leg
0.857 0.143 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.857 0.143 0.000
S01.0 Open wound of scalp
0.855 0.145 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.852 0.148 0.000
E20-E35 Disorders of other endocrine glands
0.851 0.149 0.000
M47.8 Other spondylosis
0.848 0.152 0.000
T81 Complications of procedures, not elsewhere classified
0.846 0.154 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.845 0.155 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.842 0.158 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.836 0.164 0.000
I67 Other cerebrovascular diseases
0.836 0.164 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.832 0.168 0.000
M47.9 Spondylosis, unspecified
0.832 0.168 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.830 0.170 0.000
Z50.8 Care involving use of rehabilitation procedures
0.826 0.174 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.825 0.175 0.000
C15-C26 Malignant neoplasms of digestive organs
0.824 0.176 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.823 0.177 0.000
I60 Subarachnoid haemorrhage
0.822 0.178 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.821 0.179 0.000
Z46 Fitting and adjustment of other devices
0.821 0.179 0.000
S40-S49 Injuries to the shoulder and upper arm
0.819 0.181 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.818 0.182 0.000
Z50.5 Speech therapy
0.816 0.184 0.000
Chapter V Mental and behavioural disorders
0.816 0.184 0.000
J09-J18 Influenza and pneumonia
0.815 0.185 0.000
E00-E07 Disorders of thyroid gland
0.815 0.185 0.000
W19.2 School, other institution and public administrative area
0.815 0.185 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.814 0.186 0.000
D80 Immunodeficiency with predominantly antibody defects
0.811 0.189 0.000
M70-M79 Other soft tissue disorders
0.811 0.189 0.000
J98 Other respiratory disorders
0.808 0.192 0.000
I30-I52 Other forms of heart disease
0.806 0.194 0.000
I61 Intracerebral haemorrhage
0.806 0.194 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.805 0.195 0.000
G62 Other polyneuropathies
0.805 0.195 0.000
I69 Sequelae of cerebrovascular disease
0.802 0.198 0.000
W19.4 Street and highway
0.802 0.198 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.801 0.199 0.000
D69.0 Allergic purpura
0.800 0.200 0.000
G30-G32 Other degenerative diseases of the nervous system
0.797 0.203 0.000
M81 Osteoporosis without pathological fracture
0.796 0.204 0.000
Z40 Prophylactic surgery
0.795 0.205 0.000
D70 Agranulocytosis
0.794 0.206 0.000
G20 Parkinson's disease
0.793 0.207 0.000
A08 Viral and other specified intestinal infections
0.791 0.209 0.000
D75 Other diseases of blood and blood-forming organs
0.791 0.209 0.000
A49 Bacterial infection of unspecified site
0.788 0.212 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.786 0.214 0.000
E50-E64 Other nutritional deficiencies
0.785 0.215 0.000
J02 Acute pharyngitis
0.784 0.216 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.783 0.217 0.000
S10-S19 Injuries to the neck
0.782 0.218 0.000
M86-M90 Other osteopathies
0.781 0.219 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.780 0.220 0.000
D86 Sarcoidosis
0.780 0.220 0.000
Z42.0 Follow-up care involving plastic surgery of head and neck
0.780 0.220 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.779 0.221 0.000
I67.8 Other specified cerebrovascular diseases
0.778 0.222 0.000
X20-X29 Contact with venomous animals and plants
0.776 0.224 0.000
Z51.3 Blood transfusion without reported diagnosis
0.774 0.226 0.000
S01.2 Open wound of nose
0.773 0.227 0.000
T93 Sequelae of injuries of lower limb
0.771 0.229 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.771 0.229 0.000
D10-D36 Benign neoplasms
0.770 0.230 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.770 0.230 0.000
S01.3 Open wound of ear
0.770 0.230 0.000
G72 Other myopathies
0.769 0.231 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.767 0.233 0.000
M65 Synovitis and tenosynovitis
0.766 0.234 0.000
E10 Insulin-dependent diabetes mellitus
0.766 0.234 0.000
J00 Acute nasopharyngitis [common cold]
0.766 0.234 0.000
J36 Peritonsillar abscess
0.765 0.235 0.000
S00.0 Superficial injury of scalp
0.762 0.238 0.000
D68.9 Coagulation defect, unspecified
0.762 0.238 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.761 0.239 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.761 0.239 0.000
A04 Other bacterial intestinal infections
0.760 0.240 0.000
U80 Agent resistant to penicillin and related antibiotics
0.760 0.240 0.000
E86 Volume depletion
0.759 0.241 0.000
D47.2 Monoclonal gammopathy
0.758 0.241 0.000
W07 Fall involving chair
0.757 0.243 0.000
A80-A89 Viral infections of the central nervous system
0.755 0.245 0.000
S50-S59 Injuries to the elbow and forearm
0.755 0.245 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.754 0.246 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.754 0.246 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.753 0.247 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.752 0.248 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.750 0.250 0.000
D89.2 Hypergammaglobulinaemia, unspecified
0.750 0.250 0.000
M91-M94 Chondropathies
0.749 0.251 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.745 0.255 0.000
D17 Benign lipomatous neoplasm
0.744 0.256 0.000
J03 Acute tonsillitis
0.743 0.257 0.000
T86 Failure and rejection of transplanted organs and tissues
0.743 0.257 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.743 0.257 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.742 0.258 0.000
D60-D64 Aplastic and other anaemias
0.741 0.259 0.000
Z22 Carrier of infectious disease
0.741 0.259 0.000
T92 Sequelae of injuries of upper limb
0.740 0.260 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.740 0.260 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.740 0.260 0.000
Z49 Care involving dialysis
0.739 0.261 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.739 0.261 0.000
M45 Ankylosing spondylitis
0.738 0.262 0.000
W50-W64 Exposure to animate mechanical forces
0.738 0.262 0.000
S00.5 Superficial injury of lip and oral cavity
0.736 0.264 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.736 0.264 0.000
S00.9 Superficial injury of head, part unspecified
0.735 0.265 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.734 0.266 0.000
I49 Other cardiac arrhythmias
0.734 0.266 0.000
Z54 Convalescence
0.734 0.266 0.000
E04 Other non-toxic goitre
0.733 0.267 0.000
M48 Other spondylopathies
0.732 0.268 0.000
Z29 Need for other prophylactic measures
0.731 0.269 0.000
E87.3 Alkalosis
0.730 0.270 0.000
W08 Fall involving other furniture
0.730 0.270 0.000
G70 Myasthenia gravis and other myoneural disorders
0.728 0.272 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.728 0.272 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.726 0.274 0.000
G71 Primary disorders of muscles
0.725 0.275 0.000
W10 Fall on and from stairs and steps
0.724 0.276 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.723 0.277 0.000
T91 Sequelae of injuries of neck and trunk
0.723 0.277 0.000
M84 Disorders of continuity of bone
0.723 0.277 0.000
Z51.1 Chemotherapy session for neoplasm
0.723 0.277 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.723 0.277 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.723 0.277 0.000
T79-T79 Certain early complications of trauma
0.723 0.277 0.000
A40 Streptococcal septicaemia
0.723 0.277 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.722 0.278 0.000
Z48 Other surgical follow-up care
0.722 0.278 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.721 0.279 0.000
J37 Chronic laryngitis and laryngotracheitis
0.720 0.280 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.719 0.281 0.000
I05-I09 Chronic rheumatic heart diseases
0.719 0.281 0.000
Z51.8 Other specified medical care
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
D55-D59 Haemolytic anaemias
0.717 0.283 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.717 0.283 0.000
Z74 Problems related to care-provider dependency
0.717 0.283 0.000
M81.9 Osteoporosis, unspecified
0.716 0.284 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
T51 Toxic effect of alcohol
0.715 0.285 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.715 0.285 0.000
D67 Hereditary factor IX deficiency
0.715 0.285 0.000
D66 Hereditary factor VIII deficiency
0.715 0.285 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.715 0.285 0.000
Z52 Donors of organs and tissues
0.715 0.285 0.000
Z44 Fitting and adjustment of external prosthetic device
0.714 0.286 0.000
D22 Melanocytic naevi
0.714 0.286 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.714 0.286 0.000
Y43 Primarily systemic agents
0.714 0.286 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.713 0.287 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.713 0.287 0.000
D80.1 Nonfamilial hypogammaglobulinaemia
0.713 0.287 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.713 0.287 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.713 0.287 0.000
B99-B99 Other infectious diseases
0.712 0.288 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.712 0.288 0.000
B65-B83 Helminthiases
0.712 0.288 0.000
B50-B64 Protozoal diseases
0.712 0.288 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.712 0.288 0.000
A75-A79 Rickettsioses
0.712 0.288 0.000
A70-A74 Other diseases caused by chlamydiae
0.712 0.288 0.000
A65-A69 Other spirochaetal diseases
0.712 0.288 0.000
A20-A28 Certain zoonotic bacterial diseases
0.712 0.288 0.000
A15-A19 Tuberculosis
0.712 0.288 0.000
D69.9 Haemorrhagic condition, unspecified
0.712 0.288 0.000
D69.8 Other specified haemorrhagic conditions
0.712 0.288 0.000
D69.5 Secondary thrombocytopenia
0.712 0.288 0.000
D69.4 Other primary thrombocytopenia
0.712 0.288 0.000
D69.2 Other nonthrombocytopenic purpura
0.712 0.288 0.000
D69.1 Qualitative platelet defects
0.712 0.288 0.000
E13 Other specified diabetes mellitus
0.712 0.288 0.000
C73 Malignant neoplasm of thyroid gland
0.712 0.288 0.000
J14 Pneumonia due to Haemophilus influenzae
0.712 0.288 0.000
Y35-Y36 Legal intervention and operations of war
0.711 0.288 0.000
Y10-Y34 Event of undetermined intent
0.711 0.288 0.000
Y00-Y09 Assault
0.711 0.288 0.000
X85-X99 Assault
0.711 0.288 0.000
X50-X57 Overexertion, travel and privation
0.711 0.288 0.000
X30-X39 Exposure to forces of nature
0.711 0.288 0.000
X10-X19 Contact with heat and hot substances
0.711 0.288 0.000
X00-X09 Exposure to smoke, fire and flames
0.711 0.288 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.711 0.288 0.000
W75-W84 Other accidental threats to breathing
0.711 0.288 0.000
W65-W74 Accidental drowning and submersion
0.711 0.288 0.000
V98-V99 Other and unspecified transport accidents
0.711 0.288 0.000
V95-V97 Air and space transport accidents
0.711 0.288 0.000
V90-V94 Water transport accidents
0.711 0.288 0.000
V70-V79 Bus occupant injured in transport accident
0.711 0.288 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.711 0.288 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.711 0.288 0.000
V40-V49 Car occupant injured in transport accident
0.711 0.288 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.711 0.288 0.000
V01-V09 Pedestrian injured in transport accident
0.711 0.288 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.711 0.288 0.000
W20-W49 Exposure to inanimate mechanical forces
0.711 0.289 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.711 0.289 0.000
J30 Vasomotor and allergic rhinitis
0.710 0.289 0.000
E87.0 Hyperosmolality and hypernatraemia
0.710 0.290 0.000
G61 Inflammatory polyneuropathy
0.710 0.290 0.000
S83.2 Tear of meniscus, current
0.709 0.291 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.709 0.291 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.709 0.291 0.000
M60-M63 Disorders of muscles
0.709 0.291 0.000
M00-M03 Infectious arthropathies
0.709 0.291 0.000
Z50.6 Orthoptic training
0.708 0.292 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.708 0.292 0.000
Z50.3 Drug rehabilitation
0.708 0.292 0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.708 0.292 0.000
S20-S29 Injuries to the thorax
0.707 0.293 0.000
M65.3 Trigger finger
0.707 0.293 0.000
E40-E46 Malnutrition
0.707 0.293 0.000
D05.0 Lobular carcinoma in situ
0.706 0.294 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.706 0.294 0.000
T90 Sequelae of injuries of head
0.705 0.295 0.000
S08 Traumatic amputation of part of head
0.705 0.295 0.000
S07 Crushing injury of head
0.705 0.295 0.000
S05 Injury of eye and orbit
0.705 0.295 0.000
S04 Injury of cranial nerves
0.705 0.295 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.705 0.295 0.000
J34 Other disorders of nose and nasal sinuses
0.704 0.296 0.000
E23 Hypofunction and other disorders of pituitary gland
0.703 0.297 0.000
M80 Osteoporosis with pathological fracture
0.703 0.297 0.000
A07 Other protozoal intestinal diseases
0.702 0.298 0.000
A06 Amoebiasis
0.702 0.298 0.000
A05 Other bacterial foodborne intoxications
0.702 0.298 0.000
A03 Shigellosis
0.702 0.298 0.000
A02 Other Salmonella infections
0.702 0.298 0.000
A01 Typhoid and paratyphoid fevers
0.702 0.298 0.000
A00 Cholera
0.702 0.298 0.000
W18 Other fall on same level
0.702 0.298 0.000
W17 Other fall from one level to another
0.702 0.298 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.702 0.298 0.000
W15 Fall from cliff
0.702 0.298 0.000
W14 Fall from tree
0.702 0.298 0.000
W12 Fall on and from scaffolding
0.702 0.298 0.000
W11 Fall on and from ladder
0.702 0.298 0.000
W09 Fall involving playground equipment
0.702 0.298 0.000
W05 Fall involving wheelchair
0.702 0.298 0.000
W04 Fall while being carried or supported by other persons
0.702 0.298 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.702 0.298 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.702 0.298 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.702 0.298 0.000
W00 Fall on same level involving ice and snow
0.702 0.298 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.702 0.298 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.701 0.299 0.000
W13 Fall from, out of or through building or structure
0.700 0.300 0.000
J98.4 Other disorders of lung
0.700 0.300 0.000
I33 Acute and subacute endocarditis
0.700 0.300 0.000
Z51.9 Medical care, unspecified
0.699 0.301 0.000
Z45.8 Adjustment and management of other implanted devices
0.699 0.301 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.698 0.302 0.000
V80-V89 Other land transport accidents
0.698 0.302 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.698 0.302 0.000
D73 Diseases of spleen
0.698 0.302 0.000
S90-S99 Injuries to the ankle and foot
0.697 0.303 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.696 0.303 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.696 0.304 0.000
Z45.1 Adjustment and management of infusion pump
0.696 0.304 0.000
J02.9 Acute pharyngitis, unspecified
0.696 0.304 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.696 0.304 0.000
T81.9 Unspecified complication of procedure
0.695 0.305 0.000
W19.8 Other specified place
0.694 0.306 0.000
W19.5 Trade and service area
0.694 0.306 0.000
W19.0 Home
0.694 0.306 0.000
W19.7 Farm
0.694 0.306 0.000
W19.6 Industrial and construction area
0.694 0.306 0.000
W19.3 Sports and athletics area
0.694 0.306 0.000
W19.1 Residential institution
0.694 0.306 0.000
T80.1 Vascular complications following infusion, transfusion and therapeutic injection
0.693 0.307 0.000
A48 Other bacterial diseases, not elsewhere classified
0.693 0.307 0.000
I77 Other disorders of arteries and arterioles
0.693 0.307 0.000
E88 Other metabolic disorders
0.693 0.307 0.000
S01.4 Open wound of cheek and temporomandibular area
0.692 0.307 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.692 0.308 0.000
E11 Non-insulin-dependent diabetes mellitus
0.692 0.308 0.000
S06 Intracranial injury
0.692 0.308 0.000
Y57 Other and unspecified drugs and medicaments
0.691 0.309 0.000
T80.2 Infections following infusion, transfusion and therapeutic injection
0.691 0.309 0.000
S01.7 Multiple open wounds of head
0.690 0.310 0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck
0.690 0.310 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.689 0.311 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.689 0.311 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.688 0.312 0.000
Z51.6 Desensitisation to allergens
0.687 0.313 0.000
G62.9 Polyneuropathy, unspecified
0.687 0.313 0.000
I67.9 Cerebrovascular disease, unspecified
0.686 0.314 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.686 0.314 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.686 0.314 0.000
E29 Testicular dysfunction
0.685 0.315 0.000
G37 Other demyelinating diseases of central nervous system
0.685 0.315 0.000
M49 Spondylopathies in diseases classified elsewhere
0.684 0.316 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.684 0.316 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.684 0.316 0.000
C25 Malignant neoplasm of pancreas
0.684 0.316 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.683 0.316 0.000
I45 Other conduction disorders
0.683 0.317 0.000
I71 Aortic aneurysm and dissection
0.683 0.317 0.000
M46 Other inflammatory spondylopathies
0.682 0.318 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.682 0.318 0.000
F60-F69 Disorders of adult personality and behaviour
0.681 0.319 0.000
J38.1 Polyp of vocal cord and larynx
0.681 0.319 0.000
X60-X84 Intentional self-harm
0.680 0.320 0.000
D84 Other immunodeficiencies
0.680 0.320 0.000
D83 Common variable immunodeficiency
0.680 0.320 0.000
D82 Immunodeficiency associated with other major defects
0.680 0.320 0.000
D81 Combined immunodeficiencies
0.680 0.320 0.000
S02 Fracture of skull and facial bones
0.679 0.321 0.000
M05-M14 Inflammatory polyarthropathies
0.678 0.322 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.678 0.322 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.678 0.322 0.000
D86.0 Sarcoidosis of lung
0.678 0.322 0.000
S01.1 Open wound of eyelid and periocular area
0.677 0.322 0.000
A49.1 Streptococcal infection, unspecified
0.677 0.323 0.000
G82 Paraplegia and tetraplegia
0.677 0.323 0.000
T87 Complications peculiar to reattachment and amputation
0.676 0.324 0.000
J35 Chronic diseases of tonsils and adenoids
0.676 0.324 0.000
G72.9 Myopathy, unspecified
0.676 0.324 0.000
M47.82 Other spondylosis (Cervical region)
0.676 0.324 0.000
E10.1 With ketoacidosis
0.675 0.325 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.675 0.325 0.000
D05.1 Intraductal carcinoma in situ
0.675 0.325 0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.675 0.325 0.000
Z76 Persons encountering health services in other circumstances
0.675 0.325 0.000
R50-R69 General symptoms and signs
0.674 0.326 0.000
I00-I02 Acute rheumatic fever
0.674 0.326 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.674 0.326 0.000
J98.8 Other specified respiratory disorders
0.673 0.327 0.000
C16 Malignant neoplasm of stomach
0.672 0.328 0.000
M79.0 Rheumatism, unspecified
0.672 0.328 0.000
Y95 Nosocomial condition
0.671 0.329 0.000
E26 Hyperaldosteronism
0.671 0.329 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.671 0.329 0.000
G62.8 Other specified polyneuropathies
0.670 0.330 0.000
I49.9 Cardiac arrhythmia, unspecified
0.669 0.331 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.669 0.331 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.668 0.331 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.668 0.332 0.000
Q60-Q64 Congenital malformations of the urinary system
0.668 0.332 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.668 0.332 0.000
J32 Chronic sinusitis
0.667 0.333 0.000
M85 Other disorders of bone density and structure
0.667 0.333 0.000
M20-M25 Other joint disorders
0.665 0.335 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.664 0.336 0.000
D22.1 Melanocytic naevi of eyelid, including canthus
0.664 0.336 0.000
M65.34 Trigger finger-Hand
0.664 0.336 0.000
Z43 Attention to artificial openings
0.664 0.336 0.000
Z41 Procedures for purposes other than remedying health state
0.663 0.337 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.663 0.337 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.663 0.337 0.000
D07.5 Prostate
0.663 0.337 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.663 0.337 0.000
Q00-Q07 Congenital malformations of the nervous system
0.663 0.337 0.000
Y40 Systemic antibiotics
0.662 0.337 0.000
J01 Acute sinusitis
0.662 0.338 0.000
D68.5 Primary Thrombophilia
0.662 0.338 0.000
Z46.6 Fitting and adjustment of urinary device
0.662 0.338 0.000
S00.8 Superficial injury of other parts of head
0.661 0.339 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.660 0.340 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.660 0.340 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.660 0.340 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.660 0.340 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.660 0.340 0.000
G90-G99 Other disorders of the nervous system
0.660 0.340 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.660 0.340 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.659 0.341 0.000
M47.1 Other spondylosis with myelopathy
0.657 0.342 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.657 0.342 0.000
T98 Sequelae of other and unspecified effects of external causes
0.657 0.343 0.000
T95 Sequelae of burns, corrosions and frostbite
0.657 0.343 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.657 0.343 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.657 0.343 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.657 0.343 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.656 0.343 0.000
D74 Methaemoglobinaemia
0.656 0.343 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.656 0.343 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.656 0.343 0.000
A08.4 Viral intestinal infection, unspecified
0.656 0.343 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.656 0.344 0.000
D45 Polycythaemia vera
0.656 0.344 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.655 0.344 0.000
E85 Amyloidosis
0.655 0.345 0.000
E84 Cystic fibrosis
0.655 0.345 0.000
E79 Disorders of purine and pyrimidine metabolism
0.655 0.345 0.000
E77 Disorders of glycoprotein metabolism
0.655 0.345 0.000
E76 Disorders of glycosaminoglycan metabolism
0.655 0.345 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.655 0.345 0.000
E74 Other disorders of carbohydrate metabolism
0.655 0.345 0.000
E73 Lactose intolerance
0.655 0.345 0.000
E72 Other disorders of amino-acid metabolism
0.655 0.345 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.655 0.345 0.000
E70 Disorders of aromatic amino-acid metabolism
0.655 0.345 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.655 0.345 0.000
U88 Agent resistant to multiple antibiotics
0.655 0.345 0.000
J60-J70 Lung diseases due to external agents
0.655 0.345 0.000
R25 Abnormal involuntary movements
0.653 0.347 0.000
D22.7 Melanocytic naevi of lower limb, including hip
0.652 0.348 0.000
S81 Open wound of lower leg
0.652 0.348 0.000
S70-S79 Injuries to the hip and thigh
0.652 0.348 0.000
E87.5 Hyperkalaemia
0.651 0.349 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.651 0.349 0.000
Z42.9 Follow-up care involving plastic surgery, unspecified
0.651 0.349 0.000
Z42.8 Follow-up care involving plastic surgery of other body part
0.651 0.349 0.000
Z42.4 Follow-up care involving plastic surgery of lower extremity
0.651 0.349 0.000
Z42.3 Follow-up care involving plastic surgery of upper extremity
0.651 0.349 0.000
Z42.2 Follow-up care involving plastic surgery of other parts of trunk
0.651 0.349 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.651 0.349 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.650 0.349 0.000
J04 Acute laryngitis and tracheitis
0.650 0.349 0.000
B25-B34 Other viral diseases
0.650 0.350 0.000
M83 Adult osteomalacia
0.650 0.350 0.000
M82 Osteoporosis in diseases classified elsewhere
0.650 0.350 0.000
E34 Other endocrine disorders
0.650 0.350 0.000
J38.3 Other diseases of vocal cords
0.650 0.350 0.000
J10 Influenza due to identified influenza virus
0.649 0.350 0.000
W06 Fall involving bed
0.649 0.351 0.000
C20 Malignant neoplasm of rectum
0.649 0.351 0.000
G60 Hereditary and idiopathic neuropathy
0.647 0.352 0.000
G64 Other disorders of peripheral nervous system
0.647 0.352 0.000
T66-T78 Other and unspecified effects of external causes
0.647 0.353 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.647 0.353 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.647 0.353 0.000
M66 Spontaneous rupture of synovium and tendon
0.646 0.353 0.000
D75.1 Secondary polycythaemia
0.645 0.355 0.000
S00.7 Multiple superficial injuries of head
0.645 0.355 0.000
S00.4 Superficial injury of ear
0.645 0.355 0.000
S00.3 Superficial injury of nose
0.645 0.355 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.645 0.355 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.644 0.355 0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.644 0.356 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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