TreeWAS – Variant ID: rs12817488

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M17.1 Other primary gonarthrosis	0.820	0.180	0.000
M17 Gonarthrosis [arthrosis of knee]	0.616	0.384	0.000
M17.0 Primary gonarthrosis, bilateral	0.611	0.389	0.000
M17.2 Posttraumatic gonarthrosis, bilateral	0.493	0.507	0.000
M17.4 Other secondary gonarthrosis, bilateral	0.429	0.571	0.000
M17.5 Other secondary gonarthrosis	0.346	0.653	0.000
M17.3 Other posttraumatic gonarthrosis	0.245	0.755	0.000
M17.9 Gonarthrosis, unspecified	0.206	0.794	0.000
C44.6 Skin of upper limb, including shoulder	0.060	0.940	0.000
N18.3 Chronic kidney disease, stage 3	0.060	0.940	0.000
C43.7 Malignant melanoma of lower limb, including hip	0.000	0.968	0.032
M81.90 Osteoporosis, unspecified (Multiple sites)	0.000	0.973	0.027
C43.6 Malignant melanoma of upper limb, including shoulder	0.000	0.974	0.026
C43 Malignant melanoma of skin	0.000	0.974	0.026
C67.2 Lateral wall of bladder	0.026	0.974	0.000
C43.9 Malignant melanoma of skin, unspecified	0.000	0.975	0.025
C67 Malignant neoplasm of bladder	0.022	0.978	0.000
C67.0 Trigone of bladder	0.020	0.980	0.000
C43.4 Malignant melanoma of scalp and neck	0.000	0.980	0.020
C67.1 Dome of bladder	0.020	0.980	0.000
C43.2 Malignant melanoma of ear and external auricular canal	0.000	0.980	0.020
C67.4 Posterior wall of bladder	0.020	0.980	0.000
C43.8 Overlapping malignant melanoma of skin	0.000	0.981	0.019
M79.62 Pain in limb (Upper arm)	0.019	0.981	0.000
C67.8 Overlapping lesion of bladder	0.018	0.982	0.000
R19.8 Other specified symptoms and signs involving the digestive system and abdomen	0.000	0.982	0.018
C43.0 Malignant melanoma of lip	0.000	0.982	0.018
C43.1 Malignant melanoma of eyelid, including canthus	0.000	0.983	0.017
C67.3 Anterior wall of bladder	0.017	0.983	0.000
C67.6 Ureteric orifice	0.017	0.983	0.000
C67.7 Urachus	0.016	0.984	0.000
C50.5 Lower-outer quadrant of breast	0.000	0.984	0.016
R15 Faecal incontinence	0.000	0.985	0.015
C67.5 Bladder neck	0.015	0.985	0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.014	0.986	0.000
M81.9 Osteoporosis, unspecified	0.000	0.987	0.013
C43.3 Malignant melanoma of other and unspecified parts of face	0.000	0.987	0.013
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.000	0.988	0.012
M81.96 Osteoporosis, unspecified (Lower leg)	0.000	0.988	0.012
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.000	0.989	0.011
C67.9 Bladder, unspecified	0.010	0.990	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.000	0.990	0.010
M81.91 Osteoporosis, unspecified (Shoulder region)	0.000	0.991	0.009
M15-M19 Arthrosis	0.009	0.991	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.009	0.991	0.000
R19.0 Intra-abdominal and pelvic swelling, mass and lump	0.000	0.991	0.009
M81.94 Osteoporosis, unspecified (Hand)	0.000	0.991	0.008
M81.93 Osteoporosis, unspecified (Forearm)	0.000	0.992	0.008
N17.9 Acute renal failure, unspecified	0.008	0.992	0.000
M81.98 Osteoporosis, unspecified (Other)	0.000	0.992	0.008
R19 Other symptoms and signs involving the digestive system and abdomen	0.000	0.993	0.007
I05.1 Rheumatic mitral insufficiency	0.000	0.993	0.007
I05.9 Mitral valve disease, unspecified	0.000	0.994	0.006
I05 Rheumatic mitral valve diseases	0.000	0.994	0.006
I05.0 Mitral stenosis	0.000	0.994	0.006
T92.0 Sequelae of open wound of upper limb	0.000	0.994	0.006
J15.2 Pneumonia due to staphylococcus	0.006	0.994	0.000
G20 Parkinson's disease	0.006	0.994	0.000
R19.6 Halitosis	0.000	0.995	0.005
M15 Polyarthrosis	0.005	0.995	0.000
Q82.5 Congenital nonneoplastic naevus	0.005	0.995	0.000
R19.3 Abdominal rigidity	0.000	0.995	0.005
R19.1 Abnormal bowel sounds	0.000	0.995	0.005
Q82 Other congenital malformations of skin	0.005	0.995	0.000
M15.2 Bouchard's nodes (with arthropathy)	0.005	0.995	0.000
C53.9 Cervix uteri, unspecified	0.005	0.995	0.000
J15 Bacterial pneumonia, not elsewhere classified	0.005	0.995	0.000
I05.8 Other mitral valve diseases	0.000	0.996	0.004
C43-C44 Melanoma and other malignant neoplasms of skin	0.000	0.996	0.004
N64.1 Fat necrosis of breast	0.004	0.996	0.000
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.004	0.996	0.000
Q82.8 Other specified congenital malformations of skin	0.004	0.996	0.000
S62.30 Fracture of other metacarpal bone (closed)	0.004	0.996	0.000
R19.2 Visible peristalsis	0.000	0.996	0.004
M15.0 Primary generalised (osteo)arthrosis	0.004	0.996	0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.004	0.996	0.000
I05.2 Mitral stenosis with insufficiency	0.000	0.996	0.004
J15.1 Pneumonia due to Pseudomonas	0.004	0.996	0.000
B37.0 Candidal stomatitis	0.000	0.996	0.004
Q82.2 Mastocytosis	0.004	0.996	0.000
J15.5 Pneumonia due to Escherichia coli	0.004	0.996	0.000
L50.9 Urticaria, unspecified	0.004	0.996	0.000
M15.8 Other polyarthrosis	0.004	0.996	0.000
T92 Sequelae of injuries of upper limb	0.000	0.996	0.004
M15.9 Polyarthrosis, unspecified	0.004	0.996	0.000
M15.3 Secondary multiple arthrosis	0.004	0.996	0.000
N17 Acute renal failure	0.004	0.996	0.000
Y83.0 Surgical operation with transplant of whole organ	0.004	0.996	0.000
M21.0 Valgus deformity, not elsewhere classified	0.004	0.996	0.000
Q82.9 Congenital malformation of skin, unspecified	0.004	0.996	0.000
Q82.4 Ectodermal dysplasia (anhidrotic)	0.004	0.996	0.000
Q82.3 Incontinentia pigmenti	0.004	0.996	0.000
Q82.1 Xeroderma pigmentosum	0.004	0.996	0.000
T92.9 Sequelae of unspecified injury of upper limb	0.000	0.996	0.004
Q80-Q89 Other congenital malformations	0.004	0.996	0.000
H81.0 Meniere's disease	0.004	0.996	0.000
T92.1 Sequelae of fracture of arm	0.000	0.996	0.004
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.000	0.996	0.004
T92.2 Sequelae of fracture at wrist and hand level	0.000	0.996	0.004
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.996	0.004
J15.3 Pneumonia due to streptococcus, group B	0.003	0.996	0.000
J15.0 Pneumonia due to Klebsiella pneumoniae	0.003	0.996	0.000
J15.9 Bacterial pneumonia, unspecified	0.003	0.996	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.003	0.996	0.000
Q83 Congenital malformations of breast	0.003	0.996	0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.000	0.997	0.003
M15.00 Primary generalized (osteo)arthrosis, Multiple sites	0.003	0.997	0.000
C43.5 Malignant melanoma of trunk	0.000	0.997	0.003
M51.2 Other specified intervertebral disk displacement	0.003	0.997	0.000
M15.4 Erosive (osteo)arthrosis	0.003	0.997	0.000
M15.1 Heberden's nodes (with arthropathy)	0.003	0.997	0.000
J15.8 Other bacterial pneumonia	0.003	0.997	0.000
Q83.1 Accessory breast	0.003	0.997	0.000
Q82.0 Hereditary lymphoedema	0.003	0.997	0.000
L90.0 Lichen sclerosus et atrophicus	0.003	0.997	0.000
T92.4 Sequelae of injury of nerve of upper limb	0.000	0.997	0.003
N17.1 Acute renal failure with acute cortical necrosis	0.003	0.997	0.000
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.003	0.997	0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.000	0.997	0.003
J15.4 Pneumonia due to other streptococci	0.003	0.997	0.000
S05 Injury of eye and orbit	0.000	0.997	0.003
Q89 Other congenital malformations, not elsewhere classified	0.003	0.997	0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.003	0.997	0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.003	0.997	0.000
Q80 Congenital ichthyosis	0.003	0.997	0.000
N17.2 Acute renal failure with medullary necrosis	0.003	0.997	0.000
Q83.3 Accessory nipple	0.003	0.997	0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.000	0.997	0.003
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.003	0.997	0.000
M21.08 Valgus deformity, not elsewhere classified (Other)	0.003	0.997	0.000
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.003	0.997	0.000
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.003	0.997	0.000
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.003	0.997	0.000
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.003	0.997	0.000
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.003	0.997	0.000
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.003	0.997	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.003	0.997	0.000
Q84 Other congenital malformations of integument	0.003	0.997	0.000
Q81 Epidermolysis bullosa	0.003	0.997	0.000
J15.6 Pneumonia due to other aerobic Gram-negative bacteria	0.003	0.997	0.000
Q63.0 Accessory kidney	0.003	0.997	0.000
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.003	0.997	0.000
N17.8 Other acute renal failure	0.003	0.997	0.000
Q87.4 Marfan's syndrome	0.003	0.997	0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.000	0.997	0.003
L50 Urticaria	0.003	0.997	0.000
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.003	0.997	0.000
Q87.3 Congenital malformation syndromes involving early overgrowth	0.003	0.997	0.000
R61.9 Hyperhidrosis, unspecified	0.003	0.997	0.000
Q83.9 Congenital malformation of breast, unspecified	0.003	0.997	0.000
Q83.2 Absent nipple	0.003	0.997	0.000
Q83.0 Congenital absence of breast with absent nipple	0.003	0.997	0.000
J18.0 Bronchopneumonia, unspecified	0.003	0.997	0.000
M15.99 Polyosteoarthritis, unspecified	0.002	0.997	0.000
T92.8 Sequelae of other specified injuries of upper limb	0.000	0.997	0.003
S05.6 Penetrating wound of eyeball without foreign body	0.000	0.997	0.003
Z89.6 Acquired absence of leg above knee	0.003	0.997	0.000
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.003	0.997	0.000
Q89.2 Congenital malformations of other endocrine glands	0.003	0.997	0.000
H92.1 Otorrhoea	0.003	0.997	0.000
U89.8 Agent resistant to other single specified antibiotic	0.003	0.997	0.000
Q83.8 Other congenital malformations of breast	0.003	0.997	0.000
S05.4 Penetrating wound of orbit with or without foreign body	0.000	0.997	0.003
N81.3 Complete uterovaginal prolapse	0.000	0.997	0.003
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.003	0.997	0.000
S05.1 Contusion of eyeball and orbital tissues	0.000	0.997	0.003
F43.9 Reaction to severe stress, unspecified	0.000	0.997	0.003
L50.3 Dermatographic urticaria	0.002	0.997	0.000
S05.7 Avulsion of eye	0.000	0.997	0.002
Q80.9 Congenital ichthyosis, unspecified	0.002	0.997	0.000
Q89.9 Congenital malformation, unspecified	0.002	0.997	0.000
Q89.8 Other specified congenital malformations	0.002	0.997	0.000
Q89.7 Multiple congenital malformations, not elsewhere classified	0.002	0.997	0.000
Q89.4 Conjoined twins	0.002	0.997	0.000
Q89.3 Situs inversus	0.002	0.997	0.000
Q89.1 Congenital malformations of adrenal gland	0.002	0.997	0.000
Q89.0 Congenital malformations of spleen	0.002	0.997	0.000
C10.9 Oropharynx, unspecified	0.000	0.998	0.002
S05.8 Other injuries of eye and orbit	0.000	0.998	0.002
Q80.8 Other congenital ichthyosis	0.002	0.998	0.000
Q80.4 Harlequin foetus	0.002	0.998	0.000
Q80.3 Congenital bullous ichthyosiform erythroderma	0.002	0.998	0.000
Q80.2 Lamellar ichthyosis	0.002	0.998	0.000
Q80.1 X-linked ichthyosis	0.002	0.998	0.000
Q80.0 Ichthyosis vulgaris	0.002	0.998	0.000
M81 Osteoporosis without pathological fracture	0.000	0.998	0.002
L50.1 Idiopathic urticaria	0.002	0.998	0.000
Q81.9 Epidermolysis bullosa, unspecified	0.002	0.998	0.000
Q81.8 Other epidermolysis bullosa	0.002	0.998	0.000
Q81.2 Epidermolysis bullosa dystrophica	0.002	0.998	0.000
Q81.1 Epidermolysis bullosa letalis	0.002	0.998	0.000
Q81.0 Epidermolysis bullosa simplex	0.002	0.998	0.000
Q84.9 Congenital malformation of integument, unspecified	0.002	0.998	0.000
Q84.8 Other specified congenital malformations of integument	0.002	0.998	0.000
Q84.6 Other congenital malformations of nails	0.002	0.998	0.000
Q84.5 Enlarged and hypertrophic nails	0.002	0.998	0.000
Q84.4 Congenital leukonychia	0.002	0.998	0.000
Q84.3 Anonychia	0.002	0.998	0.000
Q84.2 Other congenital malformations of hair	0.002	0.998	0.000
Q84.1 Congenital morphological disturbances of hair, not elsewhere classified	0.002	0.998	0.000
Q84.0 Congenital alopecia	0.002	0.998	0.000
Q86.8 Other congenital malformation syndromes due to known exogenous causes	0.002	0.998	0.000
Q86.2 Dysmorphism due to warfarin	0.002	0.998	0.000
Q86.1 Foetal hydantoin syndrome	0.002	0.998	0.000
Q86.0 Foetal alcohol syndrome (dysmorphic)	0.002	0.998	0.000
Q51.2 Other doubling of uterus	0.002	0.998	0.000
F43.2 Adjustment disorders	0.000	0.998	0.002
K11.9 Disease of salivary gland, unspecified	0.000	0.998	0.002
K26.3 Acute without haemorrhage or perforation	0.002	0.998	0.000
L50.6 Contact urticaria	0.002	0.998	0.000
L50.5 Cholinergic urticaria	0.002	0.998	0.000
L50.4 Vibratory urticaria	0.002	0.998	0.000
L50.2 Urticaria due to cold and heat	0.002	0.998	0.000
S05.5 Penetrating wound of eyeball with foreign body	0.000	0.998	0.002
L50.8 Other urticaria	0.002	0.998	0.000
Q66.8 Other congenital deformities of feet	0.002	0.998	0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.000	0.998	0.002
N18 Chronic renal failure	0.002	0.998	0.000
I08.8 Other multiple valve diseases	0.000	0.998	0.002
C53 Malignant neoplasm of cervix uteri	0.002	0.998	0.000
G61.8 Other inflammatory polyneuropathies	0.000	0.998	0.002
G61.0 Guillain-Barre syndrome	0.000	0.998	0.002
G61.9 Inflammatory polyneuropathy, unspecified	0.000	0.998	0.002
N18.0 End-stage renal disease	0.002	0.998	0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.001	0.998	0.002
L50.0 Allergic urticaria	0.002	0.998	0.000
Q63 Other congenital malformations of kidney	0.002	0.998	0.000
G61 Inflammatory polyneuropathy	0.000	0.998	0.002
D22.1 Melanocytic naevi of eyelid, including canthus	0.000	0.998	0.002
Z43.6 Attention to other artificial openings of urinary tract	0.002	0.998	0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.002	0.998	0.000
M81.8 Other osteoporosis	0.000	0.998	0.002
M81.6 Localised osteoporosis [Lequesne]	0.000	0.998	0.002
M81.5 Idiopathic osteoporosis	0.000	0.998	0.002
M81.1 Postoophorectomy osteoporosis	0.000	0.998	0.002
N17.0 Acute renal failure with tubular necrosis	0.002	0.998	0.000
Q96.9 Turner's syndrome, unspecified	0.002	0.998	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.000	0.998	0.002
I05-I09 Chronic rheumatic heart diseases	0.000	0.998	0.002
K11.5 Sialolithiasis	0.000	0.998	0.002
S05.9 Injury of eye and orbit, part unspecified	0.000	0.998	0.002
Q63.8 Other specified congenital malformations of kidney	0.002	0.998	0.000
I72.3 Aneurysm of iliac artery	0.002	0.998	0.000
Q51 Congenital malformations of uterus and cervix	0.002	0.998	0.000
K11.7 Disturbances of salivary secretion	0.000	0.998	0.002
M81.0 Postmenopausal osteoporosis	0.000	0.998	0.002
Q96 Turner's syndrome	0.002	0.998	0.000
C53.8 Overlapping lesion of cervix uteri	0.002	0.998	0.000
C53.1 Exocervix	0.002	0.998	0.000
C53.0 Endocervix	0.002	0.998	0.000
L89.9 Decubitus ulcer and pressure area, unspecified	0.002	0.998	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.002	0.998	0.000
H81 Disorders of vestibular function	0.002	0.998	0.000
M18 Arthrosis of first carpometacarpal joint	0.002	0.998	0.000
Q55 Other congenital malformations of male genital organs	0.002	0.998	0.000
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)	0.000	0.998	0.002
Q51.8 Other congenital malformations of uterus and cervix	0.002	0.998	0.000
Q55.2 Other congenital malformations of testis and scrotum	0.002	0.998	0.000
Q63.3 Hyperplastic and giant kidney	0.002	0.998	0.000
S62.3 Fracture of other metacarpal bone	0.002	0.998	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.002	0.998	0.000
N60.8 Other benign mammary dysplasias	0.000	0.998	0.002
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.002	0.998	0.000
G61.1 Serum neuropathy	0.000	0.998	0.002
M20.3 Other deformity of hallux (acquired)	0.002	0.998	0.000
I06 Rheumatic aortic valve diseases	0.000	0.998	0.002
Q66 Congenital deformities of feet	0.002	0.998	0.000
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
I06.0 Rheumatic aortic stenosis	0.000	0.998	0.002
M81.2 Osteoporosis of disuse	0.000	0.998	0.001
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.000	0.998	0.001
M81.18 Postoophorectomy osteoporosis (Other)	0.000	0.998	0.001
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.000	0.998	0.001
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.000	0.998	0.001
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.000	0.998	0.001
M81.14 Postoophorectomy osteoporosis (Hand)	0.000	0.998	0.001
M81.13 Postoophorectomy osteoporosis (Forearm)	0.000	0.998	0.001
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.000	0.998	0.001
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.000	0.998	0.001
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.000	0.998	0.001
M81.59 Idiopathic osteoporosis (Site unspecified)	0.000	0.998	0.001
M81.58 Idiopathic osteoporosis (Other)	0.000	0.998	0.001
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.000	0.998	0.001
M81.56 Idiopathic osteoporosis (Lower leg)	0.000	0.998	0.001
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.000	0.998	0.001
M81.54 Idiopathic osteoporosis (Hand)	0.000	0.998	0.001
M81.53 Idiopathic osteoporosis (Forearm)	0.000	0.998	0.001
M81.52 Idiopathic osteoporosis (Upper arm)	0.000	0.998	0.001
M81.51 Idiopathic osteoporosis (Shoulder region)	0.000	0.998	0.001
M81.50 Idiopathic osteoporosis (Multiple sites)	0.000	0.998	0.001
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.000	0.998	0.001
M81.68 Localized osteoporosis [Lequesne] (Other)	0.000	0.998	0.001
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.000	0.998	0.001
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.000	0.998	0.001
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.000	0.998	0.001
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.000	0.998	0.001
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.000	0.998	0.001
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.000	0.998	0.001
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.000	0.998	0.001
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.000	0.998	0.001
M81.89 Other osteoporosis (Site unspecified)	0.000	0.998	0.001
M81.88 Other osteoporosis (Other)	0.000	0.998	0.001
M81.87 Other osteoporosis (Ankle and foot)	0.000	0.998	0.001
M81.86 Other osteoporosis (Lower leg)	0.000	0.998	0.001
M81.85 Other osteoporosis (Pelvic region and thigh)	0.000	0.998	0.001
M81.84 Other osteoporosis (Hand)	0.000	0.998	0.001
M81.83 Other osteoporosis (Forearm)	0.000	0.998	0.001
M81.82 Other osteoporosis (Upper arm)	0.000	0.998	0.001
M81.81 Other osteoporosis (Shoulder region)	0.000	0.998	0.001
M81.80 Other osteoporosis (Multiple sites)	0.000	0.998	0.001
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.002	0.998	0.000
Q98.4 Klinefelter's syndrome, unspecified	0.002	0.998	0.000
N17-N19 Renal failure	0.002	0.998	0.000
Q50-Q56 Congenital malformations of genital organs	0.002	0.998	0.000
H81.9 Disorder of vestibular function, unspecified	0.002	0.998	0.000
U51.0 Not Previously admitted to a psyciatric hospital	0.000	0.998	0.002
Q85 Phakomatoses, not elsewhere classified	0.001	0.998	0.000
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.000	0.998	0.001
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.000	0.998	0.001
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.000	0.998	0.001
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.000	0.998	0.001
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.000	0.998	0.001
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.000	0.998	0.001
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.000	0.998	0.001
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.000	0.998	0.001
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.000	0.998	0.001
K65.9 Peritonitis, unspecified	0.002	0.998	0.000
I07 Rheumatic tricuspid valve diseases	0.000	0.998	0.002
Q64 Other congenital malformations of urinary system	0.002	0.998	0.000
U89 Agent resistant to other and unspecified antibiotics	0.002	0.998	0.000
M43.17 Spondylolisthesis (Lumbosacral region)	0.002	0.998	0.000
G57.0 Lesion of sciatic nerve	0.000	0.998	0.002
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.002	0.998	0.000
D59.1 Other autoimmune haemolytic anaemias	0.002	0.998	0.000
L40.0 Psoriasis vulgaris	0.002	0.998	0.000
S72.10 Pertrochanteric fracture (closed)	0.000	0.998	0.002
H81.3 Other peripheral vertigo	0.002	0.998	0.000
L72.8 Other follicular cysts of skin and subcutaneous tissue	0.000	0.998	0.002
Q66.9 Congenital deformity of feet, unspecified	0.002	0.998	0.000
M81.08 Postmenopausal osteoporosis (Other)	0.000	0.998	0.001
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.000	0.998	0.001
M81.06 Postmenopausal osteoporosis (Lower leg)	0.000	0.998	0.001
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.000	0.998	0.001
M81.04 Postmenopausal osteoporosis (Hand)	0.000	0.998	0.001
M81.03 Postmenopausal osteoporosis (Forearm)	0.000	0.998	0.001
M81.02 Postmenopausal osteoporosis (Upper arm)	0.000	0.998	0.001
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.000	0.998	0.001
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.000	0.998	0.001
H81.2 Vestibular neuronitis	0.002	0.998	0.000
K55.0 Acute vascular disorders of intestine	0.000	0.998	0.002
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.001	0.998	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.001	0.998	0.000
Q51.6 Embryonic cyst of cervix	0.001	0.998	0.000
Q51.5 Agenesis and aplasia of cervix	0.001	0.998	0.000
Q51.0 Agenesis and aplasia of uterus	0.001	0.998	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.002	0.998	0.000
Q96.8 Other variants of Turner's syndrome	0.001	0.998	0.000
Q96.4 Mosaicism, 45,X/other cell line(s) with abnormal sex chromosome	0.001	0.998	0.000
Q96.3 Mosaicism, 45,X/46,XX or XY	0.001	0.998	0.000
Q96.2 Karyotype 46,X with abnormal sex chromosome, except iso (Xq)	0.001	0.998	0.000
Q96.1 Karyotype 46,X iso (Xq)	0.001	0.998	0.000
Q96.0 Karyotype 45,X	0.001	0.998	0.000
Q52 Other congenital malformations of female genitalia	0.002	0.998	0.000
G20-G26 Extrapyramidal and movement disorders	0.002	0.998	0.000
M62.58 Muscle wasting and atrophy, not elsewhere classified (Other)	0.002	0.998	0.000
S72.30 Fracture of shaft of femur (closed)	0.000	0.998	0.002
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.001	0.998	0.000
Q55.0 Absence and aplasia of testis	0.001	0.998	0.000
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.000	0.998	0.001
H81.4 Vertigo of central origin	0.001	0.998	0.000
Q60-Q64 Congenital malformations of the urinary system	0.002	0.998	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.002	0.998	0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.001	0.998	0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.001	0.998	0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.001	0.998	0.000
Q55.9 Congenital malformation of male genital organ, unspecified	0.001	0.998	0.000
Q55.8 Other specified congenital malformations of male genital organs	0.001	0.998	0.000
Q55.5 Congenital absence and aplasia of penis	0.001	0.998	0.000
Q55.3 Atresia of vas deferens	0.001	0.998	0.000
Q55.1 Hypoplasia of testis and scrotum	0.001	0.998	0.000
Q66.2 Metatarsus varus	0.001	0.998	0.000
F43 Reaction to severe stress, and adjustment disorders	0.000	0.998	0.002
S02.50 Fracture of tooth (closed)	0.002	0.998	0.000
I06.1 Rheumatic aortic insufficiency	0.000	0.998	0.001
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.002	0.998	0.000
Q53.1 Undescended testicle, unilateral	0.000	0.998	0.001
Q53 Undescended testicle	0.001	0.998	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.001	0.998	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.001	0.998	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.001	0.998	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.001	0.998	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.001	0.998	0.000
M62.51 Muscle wasting and atrophy, not elsewhere classified (Shoulder region)	0.001	0.998	0.000
I06.8 Other rheumatic aortic valve diseases	0.000	0.998	0.001
Q31.3 Laryngocele	0.001	0.998	0.000
Q55.6 Other congenital malformations of penis	0.001	0.998	0.000
Q63.2 Ectopic kidney	0.001	0.998	0.000
Q66.5 Congenital pes planus	0.001	0.998	0.000
Q66.4 Talipes calcaneovalgus	0.001	0.998	0.000
Q66.1 Talipes calcaneovarus	0.001	0.998	0.000
I09 Other rheumatic heart diseases	0.000	0.998	0.001
Q90 Down's syndrome	0.001	0.998	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.001	0.998	0.000
M81.29 Osteoporosis of disuse (Site unspecified)	0.000	0.998	0.001
M81.28 Osteoporosis of disuse (Other)	0.000	0.998	0.001
M81.27 Osteoporosis of disuse (Ankle and foot)	0.000	0.998	0.001
M81.26 Osteoporosis of disuse (Lower leg)	0.000	0.998	0.001
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.000	0.998	0.001
M81.24 Osteoporosis of disuse (Hand)	0.000	0.998	0.001
M81.23 Osteoporosis of disuse (Forearm)	0.000	0.998	0.001
M81.22 Osteoporosis of disuse (Upper arm)	0.000	0.998	0.001
M81.21 Osteoporosis of disuse (Shoulder region)	0.000	0.998	0.001
Q64.7 Other congenital malformations of bladder and urethra	0.001	0.998	0.000
G21 Secondary Parkinsonism	0.001	0.998	0.000
M54.17 Radiculopathy (Lumbosacral region)	0.001	0.998	0.000
L53.8 Other specified erythematous conditions	0.001	0.998	0.000
L81.4 Other melanin hyperpigmentation	0.000	0.998	0.002
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.001	0.998	0.000
Q52.5 Fusion of labia	0.001	0.998	0.000
Q66.7 Pes cavus	0.001	0.998	0.000
Q66.0 Talipes equinovarus	0.001	0.998	0.000
Q98.9 Sex chromosome abnormality, male phenotype, unspecified	0.001	0.998	0.000
Q98.8 Other specified sex chromosome abnormalities, male phenotype	0.001	0.998	0.000
Q98.7 Male with sex chromosome mosaicism	0.001	0.998	0.000
Q98.6 Male with structurally abnormal sex chromosome	0.001	0.998	0.000
Q98.5 Karyotype 47,XYY	0.001	0.998	0.000
Q98.3 Other male with 46,XX karyotype	0.001	0.998	0.000
Q98.2 Klinefelter's syndrome, male with 46,XX karyotype	0.001	0.998	0.000
Q98.1 Klinefelter's syndrome, male with more than two X chromosomes	0.001	0.998	0.000
Q98.0 Klinefelter's syndrome karyotype 47,XXY	0.001	0.998	0.000
Z89.2 Acquired absence of upper limb above wrist	0.001	0.998	0.000
Q31 Congenital malformations of larynx	0.001	0.998	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.001	0.998	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.001	0.998	0.000
Q85.1 Tuberous sclerosis	0.001	0.998	0.000
Q54 Hypospadias	0.001	0.998	0.000
M19.21 Other secondary arthrosis (Shoulder region)	0.001	0.999	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.999	0.001
I07.9 Tricuspid valve disease, unspecified	0.000	0.999	0.001
I07.8 Other tricuspid valve diseases	0.000	0.999	0.001
I07.2 Tricuspid stenosis with insufficiency	0.000	0.999	0.001
I07.0 Tricuspid stenosis	0.000	0.999	0.001
Q53.2 Undescended testicle, bilateral	0.001	0.999	0.000
Q64.9 Congenital malformation of urinary system, unspecified	0.001	0.999	0.000
Q64.8 Other specified congenital malformations of urinary system	0.001	0.999	0.000
Q64.6 Congenital diverticulum of bladder	0.001	0.999	0.000
Q64.5 Congenital absence of bladder and urethra	0.001	0.999	0.000
Q64.2 Congenital posterior urethral valves	0.001	0.999	0.000
Q64.1 Exstrophy of urinary bladder	0.001	0.999	0.000
Q64.0 Epispadias	0.001	0.999	0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)	0.001	0.999	0.000
M54.16 Radiculopathy (Lumbar region)	0.001	0.999	0.000
H81.8 Other disorders of vestibular function	0.001	0.999	0.000
I74.8 Embolism and thrombosis of other arteries	0.000	0.999	0.001
Q52.4 Other congenital malformations of vagina	0.001	0.999	0.000
Q54.9 Hypospadias, unspecified	0.001	0.999	0.000
Q64.4 Malformation of urachus	0.001	0.999	0.000
Q66.6 Other congenital valgus deformities of feet	0.001	0.999	0.000
U89.9 Agent resistant to unspecified antibiotic	0.001	0.999	0.000
I07.1 Tricuspid insufficiency	0.000	0.999	0.001
K11 Diseases of salivary glands	0.000	0.999	0.001
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.001	0.999	0.000
M62.55 Muscle wasting and atrophy, not elsewhere classified (Pelvic region and thigh)	0.001	0.999	0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.000	0.999	0.001
S62.31 Fracture of other metacarpal bone (open)	0.001	0.999	0.000
N18.1 Chronic kidney disease, stage 1	0.001	0.999	0.000
Q52.9 Congenital malformation of female genitalia, unspecified	0.001	0.999	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.001	0.999	0.000
Q52.7 Other congenital malformations of vulva	0.001	0.999	0.000
Q52.6 Congenital malformation of clitoris	0.001	0.999	0.000
Q52.3 Imperforate hymen	0.001	0.999	0.000
Q52.2 Congenital rectovaginal fistula	0.001	0.999	0.000
Q52.0 Congenital absence of vagina	0.001	0.999	0.000
Q53.9 Undescended testicle, unspecified	0.001	0.999	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.001	0.999	0.000
G22 Parkinsonism in diseases classified elsewhere	0.001	0.999	0.000
C34.0 Main bronchus	0.001	0.999	0.000
C68.0 Urethra	0.001	0.999	0.000
G62.0 Drug-induced polyneuropathy	0.000	0.999	0.001
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.999	0.001
Q51.4 Unicornate uterus	0.001	0.999	0.000
Q52.1 Doubling of vagina	0.001	0.999	0.000
C10 Malignant neoplasm of oropharynx	0.000	0.999	0.001
G23 Other degenerative diseases of basal ganglia	0.001	0.999	0.000
Q30 Congenital malformations of nose	0.001	0.999	0.000
Y88 Sequelae of surgical and medical care as external cause	0.001	0.999	0.000
M62.57 Muscle wasting and atrophy, not elsewhere classified (Ankle and foot)	0.001	0.999	0.000
M62.53 Muscle wasting and atrophy, not elsewhere classified (Forearm)	0.001	0.999	0.000
M62.52 Muscle wasting and atrophy, not elsewhere classified (Upper arm)	0.001	0.999	0.000
F43.8 Other reactions to severe stress	0.000	0.999	0.001
G21.9 Secondary Parkinsonism, unspecified	0.001	0.999	0.000
G21.4 Vascular parkinsonism	0.001	0.999	0.000
G21.1 Other drug-induced secondary Parkinsonism	0.001	0.999	0.000
M81.4 Drug-induced osteoporosis	0.000	0.999	0.001
Q66.3 Other congenital varus deformities of feet	0.001	0.999	0.000
C64-C68 Malignant neoplasms of urinary tract	0.001	0.999	0.000
Q35-Q37 Cleft lip and cleft palate	0.001	0.999	0.000
I09.8 Other specified rheumatic heart diseases	0.000	0.999	0.001
I09.2 Chronic rheumatic pericarditis	0.000	0.999	0.001
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations