TreeWAS – Variant ID: rs12893597

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C25.9 Pancreas, unspecified	0.409	0.591	0.000
C25 Malignant neoplasm of pancreas	0.401	0.599	0.000
C25.0 Head of pancreas	0.394	0.606	0.000
C25.2 Tail of pancreas	0.336	0.663	0.000
C25.8 Overlapping lesion of pancreas	0.334	0.666	0.000
C25.3 Pancreatic duct	0.301	0.699	0.000
C25.7 Other parts of pancreas	0.288	0.712	0.000
C25.4 Endocrine pancreas	0.288	0.712	0.000
C25.1 Body of pancreas	0.281	0.719	0.000
C15-C26 Malignant neoplasms of digestive organs	0.100	0.900	0.000
C16 Malignant neoplasm of stomach	0.099	0.901	0.000
C21 Malignant neoplasm of anus and anal canal	0.090	0.910	0.000
C16.2 Body of stomach	0.089	0.911	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.087	0.913	0.000
C16.5 Lesser curvature of stomach, unspecified	0.086	0.914	0.000
C16.0 Cardia	0.082	0.918	0.000
C22.1 Intrahepatic bile duct carcinoma	0.081	0.919	0.000
C16.6 Greater curvature of stomach, unspecified	0.078	0.922	0.000
C16.3 Pyloric antrum	0.076	0.924	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.074	0.926	0.000
C21.0 Anus, unspecified	0.074	0.926	0.000
C21.1 Anal canal	0.073	0.927	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.071	0.929	0.000
C16.8 Overlapping lesion of stomach	0.071	0.929	0.000
C16.4 Pylorus	0.071	0.929	0.000
C16.1 Fundus of stomach	0.071	0.929	0.000
C16.9 Stomach, unspecified	0.069	0.931	0.000
C17 Malignant neoplasm of small intestine	0.066	0.934	0.000
C21.2 Cloacogenic zone	0.064	0.935	0.000
C23 Malignant neoplasm of gallbladder	0.064	0.936	0.000
C22.0 Liver cell carcinoma	0.064	0.936	0.000
C22.7 Other specified carcinomas of liver	0.062	0.938	0.000
C22.4 Other sarcomas of liver	0.062	0.938	0.000
C22.3 Angiosarcoma of liver	0.062	0.938	0.000
C22.2 Hepatoblastoma	0.062	0.938	0.000
C24.9 Biliary tract, unspecified	0.061	0.939	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.057	0.942	0.000
C24.0 Extrahepatic bile duct	0.054	0.946	0.000
C24.8 Overlapping lesion of biliary tract	0.053	0.946	0.000
C18.7 Sigmoid colon	0.000	0.948	0.052
C17.2 Ileum	0.049	0.951	0.000
C17.8 Overlapping lesion of small intestine	0.047	0.952	0.000
C17.3 Meckel's diverticulum	0.047	0.952	0.000
C22.9 Liver, unspecified	0.047	0.953	0.000
C17.0 Duodenum	0.046	0.954	0.000
C24.1 Ampulla of Vater	0.045	0.955	0.000
C17.9 Small intestine, unspecified	0.044	0.955	0.000
C17.1 Jejunum	0.044	0.955	0.000
C26.9 Ill-defined sites within the digestive system	0.041	0.958	0.000
C26.8 Overlapping lesion of digestive system	0.041	0.958	0.000
C26.1 Spleen	0.041	0.958	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.032	0.968	0.000
C15 Malignant neoplasm of oesophagus	0.029	0.971	0.000
C26.0 Intestinal tract, part unspecified	0.027	0.973	0.000
D86.9 Sarcoidosis, unspecified	0.022	0.978	0.000
C15.4 Middle third of oesophagus	0.022	0.978	0.000
C15.8 Overlapping lesion of oesophagus	0.021	0.979	0.000
C15.2 Abdominal part of oesophagus	0.021	0.979	0.000
C15.1 Thoracic part of oesophagus	0.021	0.979	0.000
C15.0 Cervical part of oesophagus	0.021	0.979	0.000
R09.0 Asphyxia	0.019	0.981	0.000
C15.3 Upper third of oesophagus	0.019	0.981	0.000
C20 Malignant neoplasm of rectum	0.017	0.983	0.000
R09.2 Respiratory arrest	0.017	0.983	0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.017	0.983	0.000
C18 Malignant neoplasm of colon	0.005	0.984	0.011
R09.3 Abnormal sputum	0.015	0.985	0.000
D86 Sarcoidosis	0.015	0.985	0.000
D86.0 Sarcoidosis of lung	0.014	0.986	0.000
E14.3 With ophthalmic complications	0.013	0.987	0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.012	0.987	0.000
C18.1 Appendix	0.002	0.988	0.009
C18.8 Overlapping lesion of colon	0.004	0.988	0.008
C18.3 Hepatic flexure	0.002	0.989	0.010
C18.5 Splenic flexure	0.002	0.989	0.009
E14 Unspecified diabetes mellitus	0.011	0.989	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.011	0.989	0.000
C15.9 Oesophagus, unspecified	0.011	0.989	0.000
D86.1 Sarcoidosis of lymph nodes	0.011	0.989	0.000
D86.3 Sarcoidosis of skin	0.011	0.989	0.000
C18.4 Transverse colon	0.002	0.990	0.008
I46.0 Cardiac arrest with successful resuscitation	0.010	0.990	0.000
E10.5 With peripheral circulatory complications	0.009	0.991	0.000
D86.8 Sarcoidosis of other and combined sites	0.009	0.991	0.000
E14.6 With other specified complications	0.009	0.991	0.000
E46 Unspecified protein-energy malnutrition	0.009	0.991	0.000
C18.6 Descending colon	0.004	0.991	0.005
C15.5 Lower third of oesophagus	0.009	0.991	0.000
E10 Insulin-dependent diabetes mellitus	0.009	0.991	0.000
R09.1 Pleurisy	0.009	0.991	0.000
E14.5 With peripheral circulatory complications	0.008	0.992	0.000
E10-E14 Diabetes mellitus	0.008	0.992	0.000
E14.9 Without complications	0.008	0.992	0.000
E14.8 With unspecified complications	0.008	0.992	0.000
E14.7 With multiple complications	0.008	0.992	0.000
E14.2 Withrenal complications	0.008	0.992	0.000
E14.0 With coma	0.008	0.992	0.000
E14.4 With neurological complications	0.008	0.992	0.000
E14.1 With ketoacidosis	0.008	0.992	0.000
E10.9 Without complications	0.008	0.992	0.000
E10.1 With ketoacidosis	0.008	0.992	0.000
E13 Other specified diabetes mellitus	0.007	0.993	0.000
E10.0 With coma	0.007	0.993	0.000
C18.9 Colon, unspecified	0.001	0.993	0.006
C18.2 Ascending colon	0.006	0.993	0.002
E10.7 With multiple complications	0.006	0.993	0.000
E13.3 With ophthalmic complications	0.007	0.993	0.000
E10.2 With renal complications	0.006	0.994	0.000
E10.6 With other specified complications	0.006	0.994	0.000
E10.4 With neurological complications	0.006	0.994	0.000
E12 Malnutrition-related diabetes mellitus	0.006	0.994	0.000
C18.0 Caecum	0.004	0.994	0.002
E13.9 Without complications	0.006	0.994	0.000
D80-D89 Certain disorders involving the immune mechanism	0.006	0.994	0.000
E10.8 With unspecified complications	0.006	0.994	0.000
G99.2 Myelopathy in diseases classified elsewhere	0.006	0.994	0.000
E13.8 With unspecified complications	0.005	0.994	0.000
E13.7 With multiple complications	0.005	0.994	0.000
E13.6 With other specified complications	0.005	0.994	0.000
E13.5 With peripheral circulatory complications	0.005	0.994	0.000
E13.4 With neurological complications	0.005	0.994	0.000
E13.2 With renal complications	0.005	0.994	0.000
E13.1 With ketoacidosis	0.005	0.994	0.000
E13.0 With coma	0.005	0.994	0.000
E40-E46 Malnutrition	0.005	0.995	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.005	0.995	0.000
N88.2 Stricture and stenosis of cervix uteri	0.005	0.995	0.000
D89.1 Cryoglobulinaemia	0.005	0.995	0.000
E12.9 Without complications	0.005	0.995	0.000
E12.8 With unspecified complications	0.005	0.995	0.000
E12.7 With multiple complications	0.005	0.995	0.000
E12.6 With other specified complications	0.005	0.995	0.000
E12.5 With peripheral circulatory complications	0.005	0.995	0.000
E12.4 With neurological complications	0.005	0.995	0.000
E12.3 With ophthalmic complications	0.005	0.995	0.000
E12.2 With renal complications	0.005	0.995	0.000
E12.1 With ketoacidosis	0.005	0.995	0.000
E12.0 With coma	0.005	0.995	0.000
R41.3 Other amnesia	0.005	0.995	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.005	0.995	0.000
D82 Immunodeficiency associated with other major defects	0.004	0.995	0.000
D81 Combined immunodeficiencies	0.004	0.995	0.000
D83 Common variable immunodeficiency	0.004	0.996	0.000
K62.3 Rectal prolapse	0.004	0.996	0.000
D84 Other immunodeficiencies	0.004	0.996	0.000
E10.3 With ophthalmic complications	0.004	0.996	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.004	0.996	0.000
G96.0 Cerebrospinal fluid leak	0.004	0.996	0.000
F05.9 Delirium, unspecified	0.004	0.996	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.004	0.996	0.000
S32.00 Fracture of lumbar vertebra (closed)	0.000	0.996	0.004
E44 Protein-energy malnutrition of moderate and mild degree	0.004	0.996	0.000
E45 Retarded development following protein-energy malnutrition	0.004	0.996	0.000
E43 Unspecified severe protein-energy malnutrition	0.004	0.996	0.000
E42 Marasmic kwashiorkor	0.004	0.996	0.000
E41 Nutritional marasmus	0.004	0.996	0.000
E40 Kwashiorkor	0.004	0.996	0.000
D89.3 Immune reconstitution syndrome	0.004	0.996	0.000
Z98.0 Intestinal bypass and anastomosis status	0.004	0.996	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.004	0.996	0.000
S00.0 Superficial injury of scalp	0.000	0.996	0.004
M48.02 Spinal stenosis (Cervical region)	0.004	0.996	0.000
D81.9 Combined immunodeficiency, unspecified	0.003	0.996	0.000
D81.8 Other combined immunodeficiencies	0.003	0.996	0.000
D81.7 Major histocompatibility complex class II deficiency	0.003	0.996	0.000
D81.6 Major histocompatibility complex class I deficiency	0.003	0.996	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.003	0.996	0.000
D81.4 Nezelof's syndrome	0.003	0.996	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.003	0.996	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.003	0.996	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.003	0.996	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.003	0.996	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.003	0.996	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.003	0.996	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.003	0.996	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.003	0.996	0.000
D82.2 Immunodeficiency with short-limbed stature	0.003	0.996	0.000
D82.1 Di George's syndrome	0.003	0.996	0.000
D82.0 Wiskott-Aldrich syndrome	0.003	0.996	0.000
D83.8 Other common variable immunodeficiencies	0.003	0.997	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.003	0.997	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.003	0.997	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.003	0.997	0.000
D80 Immunodeficiency with predominantly antibody defects	0.003	0.997	0.000
D83.9 Common variable immunodeficiency, unspecified	0.003	0.997	0.000
D84.8 Other specified immunodeficiencies	0.003	0.997	0.000
D84.1 Defects in the complement system	0.003	0.997	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.003	0.997	0.000
L71.9 Rosacea, unspecified	0.000	0.997	0.003
D84.9 Immunodeficiency, unspecified	0.003	0.997	0.000
E44.1 Mild protein-energy malnutrition	0.003	0.997	0.000
E44.0 Moderate protein-energy malnutrition	0.003	0.997	0.000
Z95.1 Presence of aortocoronary bypass graft	0.003	0.997	0.000
N88 Other noninflammatory disorders of cervix uteri	0.003	0.997	0.000
M25.77 Osteophyte (Ankle and foot)	0.000	0.997	0.003
K83.1 Obstruction of bile duct	0.003	0.997	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.000	0.997	0.003
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.002	0.997	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.002	0.997	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.002	0.997	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.002	0.997	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.002	0.997	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.002	0.997	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.002	0.997	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.002	0.997	0.000
N88.1 Old laceration of cervix uteri	0.003	0.997	0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.003	0.997	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.003	0.997	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.003	0.997	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.003	0.997	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.002	0.997	0.000
S42.40 Fracture of lower end of humerus (closed)	0.003	0.997	0.000
T80.2 Infections following infusion, transfusion and therapeutic injection	0.003	0.997	0.000
H61.2 Impacted cerumen	0.000	0.997	0.003
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.997	0.002
N88.8 Other specified noninflammatory disorders of cervix uteri	0.002	0.998	0.000
N88.4 Hypertrophic elongation of cervix uteri	0.002	0.998	0.000
N88.3 Incompetence of cervix uteri	0.002	0.998	0.000
N88.0 Leukoplakia of cervix uteri	0.002	0.998	0.000
K83.8 Other specified diseases of biliary tract	0.002	0.998	0.000
N88.9 Noninflammatory disorder of cervix uteri, unspecified	0.002	0.998	0.000
I46 Cardiac arrest	0.002	0.998	0.000
D68.8 Other specified coagulation defects	0.000	0.998	0.002
K83 Other diseases of biliary tract	0.002	0.998	0.000
D47.2 Monoclonal gammopathy	0.002	0.998	0.000
O23.5 Infections of the genital tract in pregnancy	0.002	0.998	0.000
G96 Other disorders of central nervous system	0.002	0.998	0.000
M47.96 Spondylosis, unspecified (Lumbar region)	0.000	0.998	0.002
E21.3 Hyperparathyroidism, unspecified	0.002	0.998	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.000	0.998	0.002
K83.4 Spasm of sphincter of Oddi	0.002	0.998	0.000
L30.9 Dermatitis, unspecified	0.000	0.998	0.002
T80 Complications following infusion, transfusion and therapeutic injection	0.002	0.998	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.002	0.998	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.002	0.998	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.002	0.998	0.000
F05 Delirium, not induced by alcohol and other psychoactive substances	0.002	0.998	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.002	0.998	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.002	0.998	0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere	0.002	0.998	0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere	0.002	0.998	0.000
M25.74 Osteophyte (Hand)	0.000	0.998	0.002
D47.1 Chronic myeloproliferative disease	0.002	0.998	0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.000	0.998	0.002
F05.0 Delirium not superimposed on dementia, so described	0.002	0.998	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.002	0.998	0.000
Y42.5 Other oestrogens and progestogens	0.002	0.998	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.002	0.998	0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.000	0.998	0.002
J92.0 Pleural plaque with presence of asbestos	0.002	0.998	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.001	0.998	0.001
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.002	0.998	0.000
T80.1 Vascular complications following infusion, transfusion and therapeutic injection	0.002	0.998	0.000
K83.9 Disease of biliary tract, unspecified	0.002	0.998	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.000	0.998	0.002
S32.0 Fracture of lumbar vertebra	0.000	0.998	0.002
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.002	0.998	0.000
I46.1 Sudden cardiac death, so described	0.002	0.998	0.000
L72.0 Epidermal cyst	0.000	0.998	0.002
E16.1 Other hypoglycaemia	0.002	0.998	0.000
G96.9 Disorder of central nervous system, unspecified	0.002	0.998	0.000
G96.8 Other specified disorders of central nervous system	0.002	0.998	0.000
K83.5 Biliary cyst	0.002	0.998	0.000
K83.3 Fistula of bile duct	0.002	0.998	0.000
K83.2 Perforation of bile duct	0.002	0.998	0.000
E16 Other disorders of pancreatic internal secretion	0.002	0.998	0.000
E21.0 Primary hyperparathyroidism	0.002	0.998	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.002	0.998	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.002	0.998	0.000
N42.2 Atrophy of prostate	0.000	0.998	0.002
M25.7 Osteophyte	0.000	0.998	0.002
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection	0.002	0.998	0.000
T80.6 Other serum reactions	0.002	0.998	0.000
T80.5 Anaphylactic shock due to serum	0.002	0.998	0.000
T80.4 Rh incompatibility reaction	0.002	0.998	0.000
T80.3 ABO incompatibility reaction	0.002	0.998	0.000
T80.0 Air embolism following infusion, transfusion and therapeutic injection	0.002	0.998	0.000
F05.1 Delirium superimposed on dementia	0.002	0.998	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.002	0.998	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.001	0.998	0.001
M84.0 Malunion of fracture	0.002	0.998	0.000
S22.20 Fracture of sternum (closed)	0.002	0.998	0.000
K83.0 Cholangitis	0.002	0.998	0.000
M84 Disorders of continuity of bone	0.002	0.998	0.000
R50.0 Fever with chills	0.002	0.998	0.000
M84.03 Malunion of fracture (Forearm)	0.002	0.998	0.000
N39.9 Disorder of urinary system, unspecified	0.000	0.998	0.002
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.002	0.998	0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.000	0.998	0.002
D06.9 Cervix, unspecified	0.002	0.998	0.000
Y42.7 Androgens and anabolic congeners	0.002	0.998	0.000
E15 Nondiabetic hypoglycaemic coma	0.002	0.998	0.000
M25.72 Osteophyte (Upper arm)	0.000	0.998	0.002
A49.9 Bacterial infection, unspecified	0.002	0.998	0.000
M48.00 Spinal stenosis (Multiple sites in spine)	0.002	0.998	0.000
S32.01 Fracture of lumbar vertebra (open)	0.000	0.998	0.002
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.000	0.998	0.002
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.000	0.998	0.002
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.000	0.998	0.002
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.000	0.998	0.002
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.002	0.998	0.000
E20.9 Hypoparathyroidism, unspecified	0.002	0.998	0.000
H54.7 Unspecified visual loss	0.002	0.998	0.000
D37.7 Other digestive organs	0.002	0.998	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.001	0.998	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.001	0.998	0.000
E16.4 Abnormal secretion of gastrin	0.001	0.998	0.000
E16.3 Increased secretion of glucagon	0.001	0.998	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.001	0.998	0.000
E21.4 Other specified disorders of parathyroid gland	0.001	0.998	0.000
E21.2 Other hyperparathyroidism	0.001	0.998	0.000
F05.8 Other delirium	0.001	0.998	0.000
M84.3 Stress fracture, not elsewhere classified	0.002	0.998	0.000
O23.4 Unspecified infection of urinary tract in pregnancy	0.002	0.998	0.000
L71 Rosacea	0.000	0.998	0.002
M25.79 Osteophyte (Site unspecified)	0.000	0.998	0.001
M25.73 Osteophyte (Forearm)	0.000	0.998	0.001
M25.70 Osteophyte (Multiple sites)	0.000	0.998	0.001
M84.05 Malunion of fracture (Pelvic region and thigh)	0.001	0.998	0.000
M84.04 Malunion of fracture (Hand)	0.001	0.998	0.000
M25.71 Osteophyte (Shoulder region)	0.000	0.998	0.002
M84.09 Malunion of fracture (Site unspecified)	0.001	0.998	0.000
M84.08 Malunion of fracture (Other)	0.001	0.998	0.000
M84.06 Malunion of fracture (Lower leg)	0.001	0.998	0.000
M84.00 Malunion of fracture (Multiple sites)	0.001	0.998	0.000
G95.9 Disease of spinal cord, unspecified	0.002	0.998	0.000
G96.1 Disorders of meninges, not elsewhere classified	0.001	0.998	0.000
H61.8 Other specified disorders of external ear	0.000	0.998	0.002
O23 Infections of genito-urinary tract in pregnancy	0.002	0.998	0.000
E16.2 Hypoglycaemia, unspecified	0.002	0.998	0.000
M84.9 Disorder of continuity of bone, unspecified	0.001	0.998	0.000
M84.8 Other disorders of continuity of bone	0.001	0.998	0.000
M84.2 Delayed union of fracture	0.001	0.998	0.000
O47.9 False labour, unspecified	0.000	0.998	0.002
D37.3 Appendix	0.001	0.998	0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.001	0.998	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.001	0.998	0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.001	0.998	0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.001	0.998	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.001	0.998	0.000
G97.0 Cerebrospinal fluid leak from spinal puncture	0.001	0.998	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.002	0.998	0.000
M25.75 Osteophyte (Pelvic region and thigh)	0.000	0.998	0.002
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.001	0.998	0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.001	0.998	0.000
M20.3 Other deformity of hallux (acquired)	0.000	0.998	0.002
N13.3 Other and unspecified hydronephrosis	0.002	0.998	0.000
E20 Hypoparathyroidism	0.001	0.998	0.000
N32.9 Bladder disorder, unspecified	0.000	0.998	0.002
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.000	0.998	0.001
E53.8 Deficiency of other specified B group vitamins	0.002	0.998	0.000
H54.9 Unspecified visual impairment (binocular)	0.001	0.998	0.000
I44.2 Atrioventricular block, complete	0.002	0.998	0.000
M84.4 Pathological fracture, not elsewhere classified	0.001	0.998	0.000
Z91.5 Personal history of self-harm	0.002	0.998	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.002	0.998	0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.000	0.998	0.002
D37.5 Rectum	0.001	0.998	0.000
G97.8 Other postprocedural disorders of nervous system	0.001	0.998	0.000
E53 Deficiency of other B group vitamins	0.001	0.998	0.000
E50-E64 Other nutritional deficiencies	0.001	0.998	0.000
M84.02 Malunion of fracture (Upper arm)	0.001	0.999	0.000
M84.01 Malunion of fracture (Shoulder region)	0.001	0.999	0.000
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.001	0.999	0.000
M84.38 Stress fracture, not elsewhere classified (Other)	0.001	0.999	0.000
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.001	0.999	0.000
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.001	0.999	0.000
M84.34 Stress fracture, not elsewhere classified (Hand)	0.001	0.999	0.000
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.001	0.999	0.000
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.001	0.999	0.000
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.001	0.999	0.000
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.001	0.999	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.001	0.999	0.000
N28.9 Disorder of kidney and ureter, unspecified	0.001	0.999	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.000	0.999	0.001
M25.76 Osteophyte (Lower leg)	0.000	0.999	0.001
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.001	0.999	0.000
E23.0 Hypopituitarism	0.000	0.999	0.001
G82.1 Spastic paraplegia	0.000	0.999	0.001
L71.8 Other rosacea	0.000	0.999	0.001
L71.0 Perioral dermatitis	0.000	0.999	0.001
H54 Blindness and low vision	0.001	0.999	0.000
F60.7 Dependent personality disorder	0.001	0.999	0.000
H54.5 Low vision, one eye	0.001	0.999	0.000
H54.0 Blindness, both eyes	0.001	0.999	0.000
L71.1 Rhinophyma	0.000	0.999	0.001
M11.2 Other chondrocalcinosis	0.001	0.999	0.000
M48.0 Spinal stenosis	0.001	0.999	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.001	0.999	0.000
O23.3 Infections of other parts of urinary tract in pregnancy	0.001	0.999	0.000
O23.2 Infections of urethra in pregnancy	0.001	0.999	0.000
O23.1 Infections of bladder in pregnancy	0.001	0.999	0.000
O23.0 Infections of kidney in pregnancy	0.001	0.999	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.001	0.999	0.000
E20-E35 Disorders of other endocrine glands	0.001	0.999	0.000
M84.29 Delayed union of fracture (Site unspecified)	0.001	0.999	0.000
M84.28 Delayed union of fracture (Other)	0.001	0.999	0.000
M84.27 Delayed union of fracture (Ankle and foot)	0.001	0.999	0.000
M84.26 Delayed union of fracture (Lower leg)	0.001	0.999	0.000
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.001	0.999	0.000
M84.24 Delayed union of fracture (Hand)	0.001	0.999	0.000
M84.23 Delayed union of fracture (Forearm)	0.001	0.999	0.000
M84.22 Delayed union of fracture (Upper arm)	0.001	0.999	0.000
M84.21 Delayed union of fracture (Shoulder region)	0.001	0.999	0.000
M84.20 Delayed union of fracture (Multiple sites)	0.001	0.999	0.000
M84.89 Other disorders of continuity of bone (Site unspecified)	0.001	0.999	0.000
M84.88 Other disorders of continuity of bone (Other)	0.001	0.999	0.000
M84.86 Other disorders of continuity of bone (Lower leg)	0.001	0.999	0.000
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.001	0.999	0.000
M84.84 Other disorders of continuity of bone (Hand)	0.001	0.999	0.000
M84.83 Other disorders of continuity of bone (Forearm)	0.001	0.999	0.000
M84.82 Other disorders of continuity of bone (Upper arm)	0.001	0.999	0.000
M84.81 Other disorders of continuity of bone (Shoulder region)	0.001	0.999	0.000
M84.80 Other disorders of continuity of bone (Multiple sites)	0.001	0.999	0.000
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.001	0.999	0.000
M84.98 Disorder of continuity of bone, unspecified (Other)	0.001	0.999	0.000
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.001	0.999	0.000
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.001	0.999	0.000
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.001	0.999	0.000
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.001	0.999	0.000
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.001	0.999	0.000
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.001	0.999	0.000
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.001	0.999	0.000
D47.4 Osteomyelofibrosis	0.001	0.999	0.000
G95 Other diseases of spinal cord	0.001	0.999	0.000
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.001	0.999	0.000
D37.1 Stomach	0.001	0.999	0.000
E20.8 Other hypoparathyroidism	0.001	0.999	0.000
E20.1 Pseudohypoparathyroidism	0.001	0.999	0.000
E20.0 Idiopathic hypoparathyroidism	0.001	0.999	0.000
G82.2 Paraplegia, unspecified	0.000	0.999	0.001
N42.8 Other specified disorders of prostate	0.000	0.999	0.001
G90-G99 Other disorders of the nervous system	0.001	0.999	0.000
M48.04 Spinal stenosis (Thoracic region)	0.001	0.999	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.999	0.001
S00.5 Superficial injury of lip and oral cavity	0.000	0.999	0.001
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.000	0.999	0.001
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.001	0.999	0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.001	0.999	0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.001	0.999	0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.001	0.999	0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.001	0.999	0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.001	0.999	0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.001	0.999	0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.001	0.999	0.000
D37.4 Colon	0.001	0.999	0.000
D37.2 Small intestine	0.001	0.999	0.000
G51.0 Bell's palsy	0.001	0.999	0.000
G71.1 Myotonic disorders	0.000	0.999	0.001
T88.4 Failed or difficult intubation	0.001	0.999	0.000
H61 Other disorders of external ear	0.000	0.999	0.001
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.000	0.999	0.001
E53.9 Vitamin B deficiency, unspecified	0.001	0.999	0.000
E53.1 Pyridoxine deficiency	0.001	0.999	0.000
E53.0 Riboflavin deficiency	0.001	0.999	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.001	0.999	0.000
E63 Other nutritional deficiencies	0.001	0.999	0.000
E56 Other vitamin deficiencies	0.001	0.999	0.000
E51 Thiamine deficiency	0.001	0.999	0.000
E50 Vitamin A deficiency	0.001	0.999	0.000
E60 Dietary zinc deficiency	0.001	0.999	0.000
E59 Dietary selenium deficiency	0.001	0.999	0.000
E58 Dietary calcium deficiency	0.001	0.999	0.000
E54 Ascorbic acid deficiency	0.001	0.999	0.000
E52 Niacin deficiency [pellagra]	0.001	0.999	0.000
G94 Other disorders of brain in diseases classified elsewhere	0.001	0.999	0.000
H61.1 Non-infective disorders of pinna	0.000	0.999	0.001
M11.29 Other chondrocalcinosis (Site unspecified)	0.001	0.999	0.000
M11.28 Other chondrocalcinosis (Other)	0.001	0.999	0.000
M11.27 Other chondrocalcinosis (Ankle and foot)	0.001	0.999	0.000
M11.25 Other chondrocalcinosis (Pelvic region and thigh)	0.001	0.999	0.000
M11.24 Other chondrocalcinosis (Hand)	0.001	0.999	0.000
M11.23 Other chondrocalcinosis (Forearm)	0.001	0.999	0.000
M11.22 Other chondrocalcinosis (Upper arm)	0.001	0.999	0.000
M11.21 Other chondrocalcinosis (Shoulder region)	0.001	0.999	0.000
M11.20 Other chondrocalcinosis (Multiple sites)	0.001	0.999	0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.001	0.999	0.000
G94.1 Hydrocephalus in neoplastic disease	0.001	0.999	0.000
H54.6 Unqualified visual loss, one eye	0.001	0.999	0.000
H54.3 Unqualified visual loss, both eyes	0.001	0.999	0.000
H54.1 Blindness, one eye, low vision, other eye	0.001	0.999	0.000
S00.7 Multiple superficial injuries of head	0.000	0.999	0.001
M48.05 Spinal stenosis (Thoracolumbar region)	0.001	0.999	0.000
M48.03 Spinal stenosis (Cervicothoracic region)	0.001	0.999	0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.001	0.999	0.000
M89.87 Other specified disorders of bone (Ankle and foot)	0.000	0.999	0.001
D37.9 Digestive organ, unspecified	0.001	0.999	0.000
D37.0 Lip, oral cavity and pharynx	0.001	0.999	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.001	0.999	0.000
G95.2 Cord compression, unspecified	0.001	0.999	0.000
G97.9 Postprocedural disorder of nervous system, unspecified	0.001	0.999	0.000
G97.2 Intracranial hypotension following ventricular shunting	0.001	0.999	0.000
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.001	0.999	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.001	0.999	0.000
E32 Diseases of thymus	0.001	0.999	0.000
E31 Polyglandular dysfunction	0.001	0.999	0.000
E30 Disorders of puberty, not elsewhere classified	0.001	0.999	0.000
E25 Adrenogenital disorders	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations