TreeWAS – Variant ID: rs12899618

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H74 Other disorders of middle ear and mastoid	0.000	0.944	0.056
H65-H75 Diseases of middle ear and mastoid	0.000	0.945	0.055
H71 Cholesteatoma of middle ear	0.000	0.948	0.052
H74.9 Disorder of middle ear and mastoid, unspecified	0.000	0.950	0.050
H74.0 Tympanosclerosis	0.000	0.950	0.050
H65 Nonsuppurative otitis media	0.000	0.951	0.049
H65.9 Nonsuppurative otitis media, unspecified	0.000	0.952	0.048
H72 Perforation of tympanic membrane	0.000	0.952	0.048
H74.3 Other acquired abnormalities of ear ossicles	0.000	0.953	0.047
H74.8 Other specified disorders of middle ear and mastoid	0.000	0.953	0.046
H66 Suppurative and unspecified otitis media	0.000	0.956	0.044
H69 Other disorders of Eustachian tube	0.000	0.957	0.043
H65.3 Chronic mucoid otitis media	0.000	0.957	0.043
H72.9 Perforation of tympanic membrane, unspecified	0.000	0.957	0.043
H74.4 Polyp of middle ear	0.000	0.959	0.041
H74.2 Discontinuity and dislocation of ear ossicles	0.000	0.960	0.040
H74.1 Adhesive middle ear disease	0.000	0.960	0.040
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.961	0.039
H68 Eustachian salpingitis and obstruction	0.000	0.961	0.039
H67 Otitis media in diseases classified elsewhere	0.000	0.961	0.039
H72.8 Other perforations of tympanic membrane	0.000	0.961	0.039
H66.3 Other chronic suppurative otitis media	0.000	0.963	0.036
H69.8 Other specified disorders of Eustachian tube	0.000	0.965	0.035
H72.2 Other marginal perforations of tympanic membrane	0.000	0.965	0.035
H73 Other disorders of tympanic membrane	0.000	0.966	0.034
H66.1 Chronic tubotympanic suppurative otitis media	0.000	0.966	0.033
H72.1 Attic perforation of tympanic membrane	0.000	0.967	0.033
H65.0 Acute serous otitis media	0.000	0.967	0.033
H66.9 Otitis media, unspecified	0.000	0.967	0.033
H65.1 Other acute nonsuppurative otitis media	0.000	0.967	0.033
H66.2 Chronic atticoantral suppurative otitis media	0.000	0.968	0.032
H66.0 Acute suppurative otitis media	0.000	0.968	0.032
H70 Mastoiditis and related conditions	0.000	0.969	0.031
H69.0 Patulous Eustachian tube	0.000	0.969	0.031
H69.9 Eustachian tube disorder, unspecified	0.000	0.969	0.031
H72.0 Central perforation of tympanic membrane	0.000	0.970	0.029
H66.4 Suppurative otitis media, unspecified	0.000	0.971	0.029
H65.4 Other chronic nonsuppurative otitis media	0.000	0.971	0.029
H67.8 Otitis media in other diseases classified elsewhere	0.000	0.971	0.028
H67.1 Otitis media in viral diseases classified elsewhere	0.000	0.971	0.028
H67.0 Otitis media in bacterial diseases classified elsewhere	0.000	0.971	0.028
H68.1 Obstruction of Eustachian tube	0.000	0.971	0.028
H68.0 Eustachian salpingitis	0.000	0.971	0.028
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.971	0.028
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.000	0.971	0.028
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.026	0.974	0.000
H73.1 Chronic myringitis	0.000	0.976	0.024
H73.0 Acute myringitis	0.000	0.976	0.024
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.024	0.976	0.000
H65.2 Chronic serous otitis media	0.000	0.976	0.023
H73.9 Disorder of tympanic membrane, unspecified	0.000	0.977	0.023
H70.8 Other mastoiditis and related conditions	0.000	0.977	0.022
H70.2 Petrositis	0.000	0.977	0.022
H70.1 Chronic mastoiditis	0.000	0.977	0.022
H70.0 Acute mastoiditis	0.000	0.977	0.022
M06.9 Rheumatoid arthritis, unspecified	0.021	0.979	0.000
H73.8 Other specified disorders of tympanic membrane	0.000	0.979	0.021
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.018	0.982	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.018	0.982	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.017	0.983	0.000
H60.9 Otitis externa, unspecified	0.000	0.984	0.016
H60 Otitis externa	0.000	0.984	0.016
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.016	0.984	0.000
Chapter VIII Diseases of the ear and mastoid process	0.000	0.984	0.016
H60-H62 Diseases of external ear	0.000	0.985	0.015
H70.9 Mastoiditis, unspecified	0.001	0.985	0.014
M19.0 Primary arthrosis of other joints	0.015	0.985	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.015	0.985	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.015	0.985	0.000
H60.1 Cellulitis of external ear	0.000	0.986	0.014
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.014	0.986	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.013	0.987	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.013	0.987	0.000
M19.00 Primary arthrosis of other joints (Multiple sites)	0.013	0.987	0.000
M06 Other rheumatoid arthritis	0.013	0.987	0.000
H60.3 Other infective otitis externa	0.000	0.987	0.013
H60.8 Other otitis externa	0.000	0.988	0.012
M19.03 Primary arthrosis of other joints (Forearm)	0.012	0.988	0.000
H60.2 Malignant otitis externa	0.000	0.988	0.012
H60.0 Abscess of external ear	0.000	0.988	0.012
M19.09 Primary arthrosis of other joints (Site unspecified)	0.011	0.989	0.000
M19.04 Primary arthrosis of other joints (Hand)	0.011	0.989	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.000	0.989	0.011
M19.02 Primary arthrosis of other joints (Upper arm)	0.011	0.989	0.000
M19.08 Primary arthrosis of other joints (Other)	0.011	0.989	0.000
M19.06 Primary arthrosis of other joints-Lower leg	0.011	0.989	0.000
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.011	0.989	0.000
M06.8 Other specified rheumatoid arthritis	0.011	0.989	0.000
H60.5 Acute otitis externa, non-infective	0.000	0.989	0.010
M06.3 Rheumatoid nodule	0.010	0.990	0.000
H60.4 Cholesteatoma of external ear	0.000	0.990	0.010
M06.2 Rheumatoid bursitis	0.009	0.990	0.000
M06.1 Adult-onset Still's disease	0.009	0.990	0.000
M06.0 Seronegative rheumatoid arthritis	0.009	0.991	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.009	0.991	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.009	0.991	0.000
M06.34 Rheumatoid nodule (Hand)	0.009	0.991	0.000
M89.9 Disorder of bone, unspecified	0.009	0.991	0.000
M89 Other disorders of bone	0.008	0.992	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.000	0.992	0.008
H62.4 Otitis externa in other diseases classified elsewhere	0.000	0.992	0.008
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.000	0.992	0.008
H62.2 Otitis externa in mycoses	0.000	0.992	0.008
H62.1 Otitis externa in viral diseases classified elsewhere	0.000	0.992	0.008
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.000	0.992	0.008
M06.4 Inflammatory polyarthropathy	0.008	0.992	0.000
K51.4 Pseudopolyposis of colon	0.008	0.992	0.000
H61 Other disorders of external ear	0.000	0.992	0.008
M06.88 Other specified rheumatoid arthritis (Other)	0.008	0.992	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.008	0.992	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.008	0.992	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.008	0.992	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.008	0.992	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.008	0.992	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.008	0.992	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.008	0.992	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.008	0.992	0.000
K51.9 Ulcerative colitis, unspecified	0.008	0.992	0.000
M89.8 Other specified disorders of bone	0.008	0.992	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.008	0.992	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.008	0.992	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.007	0.992	0.000
M06.38 Rheumatoid nodule (Other)	0.007	0.992	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.007	0.992	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.007	0.992	0.000
M06.33 Rheumatoid nodule (Forearm)	0.007	0.992	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.007	0.992	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.007	0.992	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.007	0.993	0.000
H61.9 Disorder of external ear, unspecified	0.000	0.993	0.007
M06.19 Adult-onset Still's disease (Site unspecified)	0.007	0.993	0.000
M06.18 Adult-onset Still's disease (Other)	0.007	0.993	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.007	0.993	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.007	0.993	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.007	0.993	0.000
M06.14 Adult-onset Still's disease (Hand)	0.007	0.993	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.007	0.993	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.007	0.993	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.007	0.993	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.007	0.993	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.007	0.993	0.000
M06.28 Rheumatoid bursitis (Other)	0.007	0.993	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.007	0.993	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.007	0.993	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.007	0.993	0.000
M06.24 Rheumatoid bursitis (Hand)	0.007	0.993	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.007	0.993	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.007	0.993	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.007	0.993	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.007	0.993	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.007	0.993	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.007	0.993	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.007	0.993	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.007	0.993	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.007	0.993	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.007	0.993	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.007	0.993	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.007	0.993	0.000
M89.5 Osteolysis	0.007	0.993	0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.007	0.993	0.000
M89.91 Disorder of bone, unspecified (Shoulder region)	0.007	0.993	0.000
H61.3 Acquired stenosis of external ear canal	0.000	0.993	0.007
M89.98 Disorder of bone, unspecified (Other)	0.007	0.993	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.007	0.993	0.000
M89.3 Hypertrophy of bone	0.007	0.993	0.000
K51 Ulcerative colitis	0.007	0.993	0.000
M89.88 Other specified disorders of bone (Other)	0.006	0.993	0.000
M85.8 Other specified disorders of bone density and structure	0.007	0.993	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.006	0.993	0.000
M89.99 Disorder of bone, unspecified (Site unspecified)	0.006	0.994	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.006	0.994	0.000
M89.92 Disorder of bone, unspecified (Upper arm)	0.006	0.994	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.006	0.994	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.006	0.994	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.006	0.994	0.000
M89.6 Osteopathy after poliomyelitis	0.006	0.994	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.006	0.994	0.000
M89.2 Other disorders of bone development and growth	0.006	0.994	0.000
M89.1 Epiphyseal arrest	0.006	0.994	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.006	0.994	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.006	0.994	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.006	0.994	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.006	0.994	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.006	0.994	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.006	0.994	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.006	0.994	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.006	0.994	0.000
M89.84 Other specified disorders of bone (Hand)	0.006	0.994	0.000
M86-M90 Other osteopathies	0.006	0.994	0.000
M89.55 Osteolysis (Pelvic region and thigh)	0.006	0.994	0.000
G30.9 Alzheimer's disease, unspecified	0.006	0.994	0.000
M89.89 Other specified disorders of bone (Site unspecified)	0.006	0.994	0.000
M89.83 Other specified disorders of bone (Forearm)	0.006	0.994	0.000
M89.82 Other specified disorders of bone (Upper arm)	0.006	0.994	0.000
M89.80 Other specified disorders of bone (Multiple sites)	0.006	0.994	0.000
M85.83 Other specified disorders of bone density and structure (Forearm)	0.006	0.994	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.994	0.006
M85 Other disorders of bone density and structure	0.006	0.994	0.000
M19 Other arthrosis	0.006	0.994	0.000
M89.81 Other specified disorders of bone (Shoulder region)	0.006	0.994	0.000
K51.2 Ulcerative (chronic) proctitis	0.006	0.994	0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.006	0.994	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.006	0.994	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.005	0.994	0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.006	0.994	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.006	0.994	0.000
K51.5 Mucosal proctocolitis	0.005	0.994	0.000
M89.37 Hypertrophy of bone (Ankle and foot)	0.005	0.995	0.000
M19.01 Primary arthrosis of other joints (Shoulder region)	0.005	0.995	0.000
M00.9 Pyogenic arthritis, unspecified	0.005	0.995	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.005	0.995	0.000
M80-M85 Disorders of bone density and structure	0.005	0.995	0.000
M89.0 Algoneurodystrophy	0.005	0.995	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.000	0.995	0.005
M89.59 Osteolysis (Site unspecified)	0.005	0.995	0.000
M89.58 Osteolysis (Other)	0.005	0.995	0.000
M89.57 Osteolysis (Ankle and foot)	0.005	0.995	0.000
M89.56 Osteolysis (Lower leg)	0.005	0.995	0.000
M89.54 Osteolysis (Hand)	0.005	0.995	0.000
M89.53 Osteolysis (Forearm)	0.005	0.995	0.000
M89.52 Osteolysis (Upper arm)	0.005	0.995	0.000
M89.51 Osteolysis (Shoulder region)	0.005	0.995	0.000
M89.50 Osteolysis (Multiple sites)	0.005	0.995	0.000
M87 Osteonecrosis	0.005	0.995	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.000	0.995	0.005
F00.9 Dementia in Alzheimer's disease, unspecified	0.005	0.995	0.000
M00.94 Pyogenic arthritis, unspecified (Hand)	0.005	0.995	0.000
M89.39 Hypertrophy of bone (Site unspecified)	0.005	0.995	0.000
M89.38 Hypertrophy of bone (Other)	0.005	0.995	0.000
M89.36 Hypertrophy of bone (Lower leg)	0.005	0.995	0.000
M89.35 Hypertrophy of bone (Pelvic region and thigh)	0.005	0.995	0.000
M89.34 Hypertrophy of bone (Hand)	0.005	0.995	0.000
M89.33 Hypertrophy of bone (Forearm)	0.005	0.995	0.000
M89.32 Hypertrophy of bone (Upper arm)	0.005	0.995	0.000
M89.31 Hypertrophy of bone (Shoulder region)	0.005	0.995	0.000
M89.30 Hypertrophy of bone (Multiple sites)	0.005	0.995	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.005	0.995	0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.005	0.995	0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.005	0.995	0.000
M85.84 Other specified disorders of bone density and structure (Hand)	0.005	0.995	0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.005	0.995	0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.005	0.995	0.000
H80-H83 Diseases of inner ear	0.000	0.995	0.005
M85.88 Other specified disorders of bone density and structure (Other)	0.005	0.995	0.000
M19.8 Other specified arthrosis	0.005	0.995	0.000
M00.92 Pyogenic arthritis, unspecified (Upper arm)	0.005	0.995	0.000
M84.03 Malunion of fracture (Forearm)	0.005	0.995	0.000
M05-M14 Inflammatory polyarthropathies	0.005	0.995	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.005	0.995	0.000
H61.8 Other specified disorders of external ear	0.000	0.995	0.005
M00 Pyogenic arthritis	0.005	0.995	0.000
M84 Disorders of continuity of bone	0.005	0.995	0.000
H61.0 Perichondritis of external ear	0.000	0.995	0.005
M00.90 Pyogenic arthritis, unspecified (Multiple sites)	0.005	0.995	0.000
M89.19 Epiphyseal arrest (Site unspecified)	0.004	0.995	0.000
M89.18 Epiphyseal arrest (Other)	0.004	0.995	0.000
M89.17 Epiphyseal arrest (Ankle and foot)	0.004	0.995	0.000
M89.16 Epiphyseal arrest (Lower leg)	0.004	0.995	0.000
M89.15 Epiphyseal arrest (Pelvic region and thigh)	0.004	0.995	0.000
M89.14 Epiphyseal arrest (Hand)	0.004	0.995	0.000
M89.13 Epiphyseal arrest (Forearm)	0.004	0.995	0.000
M89.12 Epiphyseal arrest (Upper arm)	0.004	0.995	0.000
M89.11 Epiphyseal arrest (Shoulder region)	0.004	0.995	0.000
M89.10 Epiphyseal arrest (Multiple sites)	0.004	0.995	0.000
M89.29 Other disorders of bone development and growth (Site unspecified)	0.004	0.995	0.000
M89.28 Other disorders of bone development and growth (Other)	0.004	0.995	0.000
M89.27 Other disorders of bone development and growth (Ankle and foot)	0.004	0.995	0.000
M89.26 Other disorders of bone development and growth (Lower leg)	0.004	0.995	0.000
M89.25 Other disorders of bone development and growth (Pelvic region and thigh)	0.004	0.995	0.000
M89.24 Other disorders of bone development and growth (Hand)	0.004	0.995	0.000
M89.23 Other disorders of bone development and growth (Forearm)	0.004	0.995	0.000
M89.22 Other disorders of bone development and growth (Upper arm)	0.004	0.995	0.000
M89.21 Other disorders of bone development and growth (Shoulder region)	0.004	0.995	0.000
M89.20 Other disorders of bone development and growth (Multiple sites)	0.004	0.995	0.000
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)	0.004	0.995	0.000
M89.48 Other hypertrophic osteoarthropathy (Other)	0.004	0.995	0.000
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)	0.004	0.995	0.000
M89.46 Other hypertrophic osteoarthropathy (Lower leg)	0.004	0.995	0.000
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)	0.004	0.995	0.000
M89.44 Other hypertrophic osteoarthropathy (Hand)	0.004	0.995	0.000
M89.43 Other hypertrophic osteoarthropathy (Forearm)	0.004	0.995	0.000
M89.42 Other hypertrophic osteoarthropathy (Upper arm)	0.004	0.995	0.000
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)	0.004	0.995	0.000
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)	0.004	0.995	0.000
M89.69 Osteopathy after poliomyelitis (Site unspecified)	0.004	0.995	0.000
M89.68 Osteopathy after poliomyelitis (Other)	0.004	0.995	0.000
M89.67 Osteopathy after poliomyelitis (Ankle and foot)	0.004	0.995	0.000
M89.66 Osteopathy after poliomyelitis (Lower leg)	0.004	0.995	0.000
M89.65 Osteopathy after poliomyelitis (Pelvic region and thigh)	0.004	0.995	0.000
M89.64 Osteopathy after poliomyelitis (Hand)	0.004	0.995	0.000
M89.63 Osteopathy after poliomyelitis (Forearm)	0.004	0.995	0.000
M89.62 Osteopathy after poliomyelitis (Upper arm)	0.004	0.995	0.000
M89.61 Osteopathy after poliomyelitis (Shoulder region)	0.004	0.995	0.000
M89.60 Osteopathy after poliomyelitis (Multiple sites)	0.004	0.995	0.000
M84.0 Malunion of fracture	0.005	0.995	0.000
M87.2 Osteonecrosis due to previous trauma	0.005	0.995	0.000
M85.0 Fibrous dysplasia (monostotic)	0.005	0.995	0.000
H61.2 Impacted cerumen	0.000	0.995	0.005
M86 Osteomyelitis	0.004	0.995	0.000
M85.9 Disorder of bone density and structure, unspecified	0.004	0.995	0.000
M85.5 Aneurysmal bone cyst	0.004	0.995	0.000
M85.4 Solitary bone cyst	0.004	0.995	0.000
M85.3 Osteitis condensans	0.004	0.995	0.000
M85.2 Hyperostosis of skull	0.004	0.995	0.000
M85.1 Skeletal fluorosis	0.004	0.995	0.000
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.004	0.995	0.000
T90 Sequelae of injuries of head	0.000	0.996	0.004
M19.2 Other secondary arthrosis	0.004	0.996	0.000
M80 Osteoporosis with pathological fracture	0.004	0.996	0.000
M85.6 Other cyst of bone	0.004	0.996	0.000
M00-M03 Infectious arthropathies	0.004	0.996	0.000
T90.9 Sequelae of unspecified injury of head	0.000	0.996	0.004
M83 Adult osteomalacia	0.004	0.996	0.000
M88 Paget's disease of bone [osteitis deformans]	0.004	0.996	0.000
H61.1 Non-infective disorders of pinna	0.000	0.996	0.004
M90 Osteopathies in diseases classified elsewhere	0.004	0.996	0.000
G30 Alzheimer's disease	0.004	0.996	0.000
M19.87 Other specified arthrosis (Ankle and foot)	0.004	0.996	0.000
M19.1 Posttraumatic arthrosis of other joints	0.004	0.996	0.000
M82 Osteoporosis in diseases classified elsewhere	0.004	0.996	0.000
M00.99 Pyogenic arthritis, unspecified (Site unspecified)	0.004	0.996	0.000
M00.98 Pyogenic arthritis, unspecified (Other)	0.004	0.996	0.000
M00.95 Pyogenic arthritis, unspecified (Pelvic region and thigh)	0.004	0.996	0.000
M00.93 Pyogenic arthritis, unspecified (Forearm)	0.004	0.996	0.000
M89.87 Other specified disorders of bone (Ankle and foot)	0.004	0.996	0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.004	0.996	0.000
M00.97 Pyogenic arthritis, unspecified (Ankle and foot)	0.004	0.996	0.000
M89.08 Algoneurodystrophy (Other)	0.004	0.996	0.000
M89.07 Algoneurodystrophy (Ankle and foot)	0.004	0.996	0.000
M89.06 Algoneurodystrophy (Lower leg)	0.004	0.996	0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.004	0.996	0.000
M89.02 Algoneurodystrophy (Upper arm)	0.004	0.996	0.000
M89.01 Algoneurodystrophy (Shoulder region)	0.004	0.996	0.000
M89.00 Algoneurodystrophy (Multiple sites)	0.004	0.996	0.000
M87.9 Osteonecrosis, unspecified	0.004	0.996	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.004	0.996	0.000
M00.91 Pyogenic arthritis, unspecified (Shoulder region)	0.004	0.996	0.000
M87.3 Other secondary osteonecrosis	0.004	0.996	0.000
M87.1 Osteonecrosis due to drugs	0.004	0.996	0.000
M87.0 Idiopathic aseptic necrosis of bone	0.004	0.996	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.004	0.996	0.000
M12 Other specific arthropathies	0.004	0.996	0.000
G30.1 Alzheimer's disease with late onset	0.004	0.996	0.000
H90-H95 Other disorders of ear	0.000	0.996	0.004
M87.8 Other osteonecrosis	0.004	0.996	0.000
M89.09 Algoneurodystrophy (Site unspecified)	0.004	0.996	0.000
M65.4 Radial styloid tenosynovitis [de Quervain]	0.004	0.996	0.000
T90.4 Sequelae of injury of eye and orbit	0.000	0.996	0.004
M65 Synovitis and tenosynovitis	0.004	0.996	0.000
M89.04 Algoneurodystrophy (Hand)	0.004	0.996	0.000
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)	0.004	0.996	0.000
S92.30 Fracture of metatarsal bone (closed)	0.004	0.996	0.000
M19.21 Other secondary arthrosis (Shoulder region)	0.004	0.996	0.000
K25.3 Acute without haemorrhage or perforation	0.004	0.996	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.000	0.996	0.004
M14 Arthropathies in other diseases classified elsewhere	0.004	0.996	0.000
M65-M68 Disorders of synovium and tendon	0.004	0.996	0.000
M89.03 Algoneurodystrophy (Forearm)	0.004	0.996	0.000
M86.9 Osteomyelitis, unspecified	0.004	0.996	0.000
M19.89 Other specified arthrosis (Site unspecified)	0.004	0.996	0.000
M19.88 Other specified arthrosis (Other)	0.004	0.996	0.000
M19.86 Other specified arthrosis (Lower leg)	0.004	0.996	0.000
M19.85 Other specified arthrosis (Pelvic region and thigh)	0.004	0.996	0.000
M19.84 Other specified arthrosis (Hand)	0.004	0.996	0.000
M19.83 Other specified arthrosis (Forearm)	0.004	0.996	0.000
M19.82 Other specified arthrosis (Upper arm)	0.004	0.996	0.000
M19.81 Other specified arthrosis (Shoulder region)	0.004	0.996	0.000
M19.80 Other specified arthrosis (Multiple sites)	0.004	0.996	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.004	0.996	0.000
M08 Juvenile arthritis	0.004	0.996	0.000
M19.12 Post-traumatic arthrosis of other joints (Upper arm)	0.004	0.996	0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.004	0.996	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.004	0.996	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.004	0.996	0.000
F00 Dementia in Alzheimer's disease	0.004	0.996	0.000
M60-M63 Disorders of muscles	0.004	0.996	0.000
M65.3 Trigger finger	0.004	0.996	0.000
M15-M19 Arthrosis	0.004	0.996	0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.004	0.996	0.000
M84.9 Disorder of continuity of bone, unspecified	0.004	0.996	0.000
M84.3 Stress fracture, not elsewhere classified	0.004	0.996	0.000
M84.2 Delayed union of fracture	0.004	0.996	0.000
R47.8 Other and unspecified speech disturbances	0.000	0.996	0.004
M65.34 Trigger finger-Hand	0.004	0.996	0.000
M00.8 Arthritis and polyarthritis due to other specified bacterial agents	0.004	0.996	0.000
M00.2 Other streptococcal arthritis and polyarthritis	0.004	0.996	0.000
M00.1 Pneumococcal arthritis and polyarthritis	0.004	0.996	0.000
M00.0 Staphylococcal arthritis and polyarthritis	0.004	0.996	0.000
M65.8 Other synovitis and tenosynovitis	0.004	0.996	0.000
M84.8 Other disorders of continuity of bone	0.004	0.996	0.000
M88.8 Paget's disease of other bones	0.004	0.996	0.000
M60.05 Infective myositis (Pelvic region and thigh)	0.004	0.996	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.004	0.996	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.004	0.996	0.000
M83.1 Senile osteomalacia	0.003	0.996	0.000
M84.09 Malunion of fracture (Site unspecified)	0.003	0.996	0.000
M84.08 Malunion of fracture (Other)	0.003	0.996	0.000
M84.04 Malunion of fracture (Hand)	0.003	0.996	0.000
M84.00 Malunion of fracture (Multiple sites)	0.003	0.996	0.000
M87.29 Osteonecrosis due to previous trauma (Site unspecified)	0.003	0.996	0.000
M87.28 Osteonecrosis due to previous trauma (Other)	0.003	0.996	0.000
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)	0.003	0.996	0.000
M87.26 Osteonecrosis due to previous trauma (Lower leg)	0.003	0.996	0.000
M87.24 Osteonecrosis due to previous trauma (Hand)	0.003	0.996	0.000
M87.23 Osteonecrosis due to previous trauma (Forearm)	0.003	0.996	0.000
M87.22 Osteonecrosis due to previous trauma (Upper arm)	0.003	0.996	0.000
M87.21 Osteonecrosis due to previous trauma (Shoulder region)	0.003	0.996	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.004	0.996	0.000
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)	0.003	0.996	0.000
M85.08 Fibrous dysplasia (monostotic) (Other)	0.003	0.996	0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)	0.003	0.996	0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)	0.003	0.996	0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)	0.003	0.996	0.000
M85.04 Fibrous dysplasia (monostotic) (Hand)	0.003	0.996	0.000
M85.03 Fibrous dysplasia (monostotic) (Forearm)	0.003	0.996	0.000
M85.02 Fibrous dysplasia (monostotic) (Upper arm)	0.003	0.996	0.000
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)	0.003	0.996	0.000
M60.0 Infective myositis	0.003	0.996	0.000
M84.4 Pathological fracture, not elsewhere classified	0.003	0.996	0.000
M60 Myositis	0.004	0.996	0.000
M81 Osteoporosis without pathological fracture	0.004	0.996	0.000
M86.99 Osteomyelitis, unspecified (Site unspecified)	0.003	0.996	0.000
M84.02 Malunion of fracture (Upper arm)	0.003	0.996	0.000
M86.8 Other osteomyelitis	0.003	0.996	0.000
M86.5 Other chronic haematogenous osteomyelitis	0.003	0.996	0.000
M86.4 Chronic osteomyelitis with draining sinus	0.003	0.996	0.000
M86.3 Chronic multifocal osteomyelitis	0.003	0.996	0.000
M86.2 Subacute osteomyelitis	0.003	0.996	0.000
M86.1 Other acute osteomyelitis	0.003	0.996	0.000
M86.0 Acute haematogenous osteomyelitis	0.003	0.996	0.000
H80 Otosclerosis	0.000	0.996	0.003
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.004	0.996	0.000
F00.1 Dementia in Alzheimer's disease with late onset	0.003	0.996	0.000
M90.1 Periostitis in other infectious diseases classified elsewhere	0.003	0.996	0.000
M85.19 Skeletal fluorosis (Site unspecified)	0.003	0.996	0.000
M85.18 Skeletal fluorosis (Other)	0.003	0.996	0.000
M85.17 Skeletal fluorosis (Ankle and foot)	0.003	0.996	0.000
M85.16 Skeletal fluorosis (Lower leg)	0.003	0.996	0.000
M85.15 Skeletal fluorosis (Pelvic region and thigh)	0.003	0.996	0.000
M85.14 Skeletal fluorosis (Hand)	0.003	0.996	0.000
M85.13 Skeletal fluorosis (Forearm)	0.003	0.996	0.000
M85.12 Skeletal fluorosis (Upper arm)	0.003	0.996	0.000
M85.11 Skeletal fluorosis (Shoulder region)	0.003	0.996	0.000
M85.10 Skeletal fluorosis (Multiple sites)	0.003	0.996	0.000
M85.29 Hyperostosis of skull-Site unspec	0.003	0.996	0.000
M85.28 Hyperostosis of skull-Other	0.003	0.996	0.000
M85.27 Hyperostosis of skull-Ankle/Foot	0.003	0.996	0.000
M85.26 Hyperostosis of skull-Lower Leg	0.003	0.996	0.000
M85.25 Hyperostosis of skull-Pelvic/Thigh	0.003	0.996	0.000
M85.24 Hyperostosis of skull-Hand	0.003	0.996	0.000
M85.23 Hyperostosis of skull-Forearm	0.003	0.996	0.000
M85.22 Hyperostosis of skull-Upper arm	0.003	0.996	0.000
M85.21 Hyperostosis of skull-Shldr region	0.003	0.996	0.000
M85.20 Hyperostosis of skull-Mult sites	0.003	0.996	0.000
M85.39 Osteitis condensans (Site unspecified)	0.003	0.996	0.000
M85.38 Osteitis condensans (Other)	0.003	0.996	0.000
M85.37 Osteitis condensans (Ankle and foot)	0.003	0.996	0.000
M85.36 Osteitis condensans (Lower leg)	0.003	0.996	0.000
M85.35 Osteitis condensans (Pelvic region and thigh)	0.003	0.996	0.000
M85.34 Osteitis condensans (Hand)	0.003	0.996	0.000
M85.33 Osteitis condensans (Forearm)	0.003	0.996	0.000
M85.32 Osteitis condensans (Upper arm)	0.003	0.996	0.000
M85.31 Osteitis condensans (Shoulder region)	0.003	0.996	0.000
M85.30 Osteitis condensans (Multiple sites)	0.003	0.996	0.000
M85.49 Solitary bone cyst (Site unspecified)	0.003	0.996	0.000
M85.48 Solitary bone cyst (Other)	0.003	0.996	0.000
M85.47 Solitary bone cyst (Ankle and foot)	0.003	0.996	0.000
M85.46 Solitary bone cyst (Lower leg)	0.003	0.996	0.000
M85.45 Solitary bone cyst (Pelvic region and thigh)	0.003	0.996	0.000
M85.44 Solitary bone cyst (Hand)	0.003	0.996	0.000
M85.43 Solitary bone cyst (Forearm)	0.003	0.996	0.000
M85.42 Solitary bone cyst (Upper arm)	0.003	0.996	0.000
M85.41 Solitary bone cyst (Shoulder region)	0.003	0.996	0.000
M85.40 Solitary bone cyst (Multiple sites)	0.003	0.996	0.000
M85.59 Aneurysmal bone cyst (Site unspecified)	0.003	0.996	0.000
M85.58 Aneurysmal bone cyst (Other)	0.003	0.996	0.000
M85.57 Aneurysmal bone cyst (Ankle and foot)	0.003	0.996	0.000
M85.56 Aneurysmal bone cyst (Lower leg)	0.003	0.996	0.000
M85.55 Aneurysmal bone cyst (Pelvic region and thigh)	0.003	0.996	0.000
M85.54 Aneurysmal bone cyst (Hand)	0.003	0.996	0.000
M85.53 Aneurysmal bone cyst (Forearm)	0.003	0.996	0.000
M85.52 Aneurysmal bone cyst (Upper arm)	0.003	0.996	0.000
M85.51 Aneurysmal bone cyst (Shoulder region)	0.003	0.996	0.000
M85.50 Aneurysmal bone cyst (Multiple sites)	0.003	0.996	0.000
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)	0.003	0.996	0.000
M85.98 Disorder of bone density and structure, unspecified (Other)	0.003	0.996	0.000
M85.97 Disorder of bone density and structure, unspecified (Ankle and foot)	0.003	0.996	0.000
M85.96 Disorder of bone density and structure, unspecified (Lower leg)	0.003	0.996	0.000
M85.95 Disorder of bone density and structure, unspecified (Pelvic region and thigh)	0.003	0.996	0.000
M85.94 Disorder of bone density and structure, unspecified (Hand)	0.003	0.996	0.000
M85.93 Disorder of bone density and structure, unspecified (Forearm)	0.003	0.996	0.000
M85.92 Disorder of bone density and structure, unspecified (Upper arm)	0.003	0.996	0.000
M85.91 Disorder of bone density and structure, unspecified (Shoulder region)	0.003	0.996	0.000
M85.90 Disorder of bone density and structure, unspecified (Multiple sites)	0.003	0.996	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.003	0.996	0.000
T90.8 Sequelae of other specified injuries of head	0.000	0.996	0.003
T90.3 Sequelae of injury of cranial nerves	0.000	0.996	0.003
T90.0 Sequelae of superficial injury of head	0.000	0.996	0.003
M85.67 Other cyst of bone (Ankle and foot)	0.003	0.997	0.000
G30.0 Alzheimer's disease with early onset	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations