TreeWAS – Variant ID: rs12900413

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
N13 Obstructive and reflux uropathy	0.718	0.282	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.704	0.296	0.000
N13.8 Other obstructive and reflux uropathy	0.700	0.300	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.699	0.301	0.000
N13.4 Hydroureter	0.665	0.335	0.000
N13.3 Other and unspecified hydronephrosis	0.651	0.349	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.573	0.427	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.541	0.459	0.000
N13.6 Pyonephrosis	0.515	0.485	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.415	0.584	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.370	0.630	0.000
N10-N16 Renal tubulo-interstitial diseases	0.311	0.689	0.000
N10 Acute tubulo-interstitial nephritis	0.262	0.738	0.000
N11 Chronic tubulo-interstitial nephritis	0.238	0.761	0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.228	0.771	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.223	0.777	0.000
N15 Other renal tubulo-interstitial diseases	0.223	0.777	0.000
N11.1 Chronic obstructive pyelonephritis	0.205	0.795	0.000
N11.8 Other chronic tubulo-interstitial nephritis	0.171	0.829	0.000
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.169	0.831	0.000
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.166	0.834	0.000
N14.4 Toxic nephropathy, not elsewhere classified	0.164	0.836	0.000
N14.3 Nephropathy induced by heavy metals	0.164	0.836	0.000
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance	0.164	0.836	0.000
N14.0 Analgesic nephropathy	0.164	0.836	0.000
N15.1 Renal and perinephric abscess	0.163	0.836	0.000
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere	0.160	0.840	0.000
N16.5 Renal tubulo-interstitial disorders in transplant rejection	0.160	0.840	0.000
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders	0.160	0.840	0.000
N16.3 Renal tubulo-interstitial disorders in metabolic diseases	0.160	0.840	0.000
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism	0.160	0.840	0.000
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases	0.160	0.840	0.000
N16.0 Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere	0.160	0.840	0.000
N15.8 Other specified renal tubulo-interstitial diseases	0.160	0.840	0.000
N15.0 Balkan nephropathy	0.160	0.840	0.000
N15.9 Renal tubulo-interstitial disease, unspecified	0.156	0.843	0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.140	0.859	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.123	0.877	0.000
M51.2 Other specified intervertebral disk displacement	0.000	0.984	0.016
M51.9 Intervertebral disk disorder, unspecified	0.000	0.984	0.016
M51 Other intervertebral disk disorders	0.000	0.985	0.015
M51.8 Other specified intervertebral disk disorders	0.000	0.987	0.013
M51.3 Other specified intervertebral disk degeneration	0.000	0.989	0.011
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.000	0.989	0.011
D36.7 Other specified sites	0.000	0.989	0.010
S61.7 Multiple open wounds of wrist and hand	0.010	0.990	0.000
M51.4 Schmorl's nodes	0.000	0.990	0.010
K80.0 Calculus of gallbladder with acute cholecystitis	0.000	0.990	0.010
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.000	0.991	0.009
D36.1 Peripheral nerves and autonomic nervous system	0.000	0.991	0.009
D36 Benign neoplasm of other and unspecified sites	0.000	0.992	0.008
M51.19 Lumbar and other intervertebral disc disorders with radiculopathy; site unspecified	0.000	0.992	0.008
M51.16 Intervertebral disc disorders w radiculopathy, lumbar region	0.000	0.992	0.008
M51.37 Other intervertebral disc degeneration, lumbosacral region	0.000	0.992	0.008
C34.9 Bronchus or lung, unspecified	0.000	0.993	0.007
D86.0 Sarcoidosis of lung	0.007	0.993	0.000
I44.7 Left bundle-branch block, unspecified	0.000	0.993	0.007
K55.2 Angiodysplasia of colon	0.000	0.993	0.007
D80 Immunodeficiency with predominantly antibody defects	0.007	0.993	0.000
D36.0 Lymph nodes	0.000	0.994	0.006
D86 Sarcoidosis	0.006	0.994	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.006	0.994	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.006	0.994	0.000
D36.9 Benign neoplasm of unspecified site	0.000	0.994	0.006
D84 Other immunodeficiencies	0.006	0.994	0.000
D80-D89 Certain disorders involving the immune mechanism	0.006	0.994	0.000
D84.9 Immunodeficiency, unspecified	0.006	0.994	0.000
Z97.4 Presence of external hearing-aid	0.000	0.994	0.006
L91.8 Other hypertrophic disorders of skin	0.000	0.994	0.006
D86.9 Sarcoidosis, unspecified	0.006	0.994	0.000
Z80.3 Family history of malignant neoplasm of breast	0.000	0.994	0.006
Z97.0 Presence of artificial eye	0.000	0.994	0.006
D84.1 Defects in the complement system	0.006	0.994	0.000
Z97 Presence of other devices	0.000	0.994	0.006
Z97.5 Presence of (intra-uterine) contraceptive device	0.000	0.994	0.006
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.005	0.995	0.000
K37 Unspecified appendicitis	0.000	0.995	0.005
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.005	0.995	0.000
Z97.1 Presence of artificial limb (complete)(partial)	0.000	0.995	0.005
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.005	0.995	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.005	0.995	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.005	0.995	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.005	0.995	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.005	0.995	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.005	0.995	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.005	0.995	0.000
S62.30 Fracture of other metacarpal bone (closed)	0.000	0.995	0.005
D86.3 Sarcoidosis of skin	0.005	0.995	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.005	0.995	0.000
M54.49 Lumbago with sciatica (Site unspecified)	0.000	0.995	0.005
D63.0 Anaemia in neoplastic disease	0.005	0.995	0.000
D84.8 Other specified immunodeficiencies	0.005	0.995	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.005	0.995	0.000
D81 Combined immunodeficiencies	0.004	0.995	0.000
L84 Corns and callosities	0.005	0.995	0.000
Z97.3 Presence of spectacles and contact lenses	0.000	0.996	0.004
D83 Common variable immunodeficiency	0.004	0.996	0.000
D82 Immunodeficiency associated with other major defects	0.004	0.996	0.000
Z97.2 Presence of dental prosthetic device (complete)(partial)	0.000	0.996	0.004
R52.9 Pain, unspecified	0.000	0.996	0.004
D86.1 Sarcoidosis of lymph nodes	0.004	0.996	0.000
M54.99 Dorsalgia, unspecified (Site unspecified)	0.000	0.996	0.004
D24 Benign neoplasm of breast	0.000	0.996	0.004
M54.4 Lumbago with sciatica	0.000	0.996	0.004
D86.8 Sarcoidosis of other and combined sites	0.004	0.996	0.000
M50-M54 Other dorsopathies	0.000	0.996	0.004
D81.9 Combined immunodeficiency, unspecified	0.003	0.996	0.000
D81.8 Other combined immunodeficiencies	0.003	0.996	0.000
D81.7 Major histocompatibility complex class II deficiency	0.003	0.996	0.000
D81.6 Major histocompatibility complex class I deficiency	0.003	0.996	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.003	0.996	0.000
D81.4 Nezelof's syndrome	0.003	0.996	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.003	0.996	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.003	0.996	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.003	0.996	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.003	0.996	0.000
M54.46 Lumbago with sciatica (Lumbar region)	0.000	0.997	0.003
J33.0 Polyp of nasal cavity	0.000	0.997	0.003
R57.0 Cardiogenic shock	0.000	0.997	0.003
C25.0 Head of pancreas	0.003	0.997	0.000
D83.8 Other common variable immunodeficiencies	0.003	0.997	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.003	0.997	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.003	0.997	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.003	0.997	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.003	0.997	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.003	0.997	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.003	0.997	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.003	0.997	0.000
D82.2 Immunodeficiency with short-limbed stature	0.003	0.997	0.000
D82.0 Wiskott-Aldrich syndrome	0.003	0.997	0.000
S62.3 Fracture of other metacarpal bone	0.000	0.997	0.003
D83.9 Common variable immunodeficiency, unspecified	0.003	0.997	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.003	0.997	0.000
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)	0.000	0.997	0.003
M54.45 Lumbago with sciatica (Thoracolumbar region)	0.000	0.997	0.003
M54.44 Lumbago with sciatica-Thoracic	0.000	0.997	0.003
M54.43 Lumbago with sciatica-Cervicothoracic	0.000	0.997	0.003
M54.42 Lumbago with sciatica-Cervical	0.000	0.997	0.003
M54.41 Lumbago with sciatica-Occipit-atl-axl	0.000	0.997	0.003
M54.40 Lumbago with sciatica (Multiple sites in spine)	0.000	0.997	0.003
M54.9 Dorsalgia, unspecified	0.000	0.997	0.003
M54 Dorsalgia	0.000	0.997	0.003
D82.1 Di George's syndrome	0.003	0.997	0.000
H54.0 Blindness, both eyes	0.003	0.997	0.000
C34 Malignant neoplasm of bronchus and lung	0.000	0.997	0.003
M54.6 Pain in thoracic spine	0.000	0.997	0.003
G58.8 Other specified mononeuropathies	0.003	0.997	0.000
M54.64 Pain in thoracic spine (Thoracic region)	0.000	0.997	0.003
C34.1 Upper lobe, bronchus or lung	0.000	0.997	0.003
M54.47 Lumbago with sciatica (Lumbosacral region)	0.000	0.997	0.003
C25 Malignant neoplasm of pancreas	0.003	0.997	0.000
H54 Blindness and low vision	0.003	0.997	0.000
M77.47 Metatarsalgia-Ankle/Foot	0.000	0.997	0.003
M53 Other dorsopathies, not elsewhere classified	0.000	0.997	0.003
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.000	0.997	0.003
M81.98 Osteoporosis, unspecified (Other)	0.000	0.997	0.003
C25.9 Pancreas, unspecified	0.003	0.997	0.000
H54.9 Unspecified visual impairment (binocular)	0.003	0.997	0.000
C25.3 Pancreatic duct	0.003	0.997	0.000
S62.31 Fracture of other metacarpal bone (open)	0.000	0.997	0.003
J33 Nasal polyp	0.000	0.997	0.003
H54.2 Low vision, both eyes	0.003	0.997	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.000	0.997	0.003
C34.0 Main bronchus	0.000	0.997	0.003
H54.7 Unspecified visual loss	0.003	0.997	0.000
M87.2 Osteonecrosis due to previous trauma	0.003	0.997	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.003	0.997	0.000
C25.1 Body of pancreas	0.003	0.997	0.000
M54.92 Dorsalgia, unspecified (Cervical region)	0.000	0.997	0.003
J33.9 Nasal polyp, unspecified	0.000	0.997	0.003
S62.50 Fracture of thumb (closed)	0.000	0.997	0.003
C25.4 Endocrine pancreas	0.002	0.997	0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.000	0.997	0.003
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.002	0.997	0.000
D89.3 Immune reconstitution syndrome	0.002	0.997	0.000
D89.1 Cryoglobulinaemia	0.002	0.997	0.000
M54.94 Dorsalgia, unspecified (Thoracic region)	0.000	0.997	0.002
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)	0.000	0.997	0.002
D89.9 Disorder involving the immune mechanism, unspecified	0.002	0.997	0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.000	0.997	0.002
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.000	0.997	0.002
H54.5 Low vision, one eye	0.002	0.997	0.000
J33.8 Other polyp of sinus	0.000	0.997	0.003
M54.0 Panniculitis affecting regions of neck and back	0.000	0.997	0.002
J33.1 Polypoid sinus degeneration	0.000	0.998	0.002
M54.12 Radiculopathy (Cervical region)	0.000	0.998	0.002
Z97.8 Presence of other specified devices	0.000	0.998	0.002
H54.6 Unqualified visual loss, one eye	0.002	0.998	0.000
O04.1 Incomplete, complicated by delayed or excessive haemorrhage	0.000	0.998	0.002
L91 Hypertrophic disorders of skin	0.000	0.998	0.002
M54.69 Pain in thoracic spine-Site unspe	0.000	0.998	0.002
M54.68 Pain in thoracic spine-Sacral/sacrococ	0.000	0.998	0.002
M54.67 Pain in thoracic spine-Lumbosacral	0.000	0.998	0.002
M54.66 Pain in thoracic spine-Lumbar	0.000	0.998	0.002
M54.65 Pain in thoracic spine (Thoracolumbar region)	0.000	0.998	0.002
M54.63 Pain in thoracic spine (Cervicothoracic region)	0.000	0.998	0.002
M54.62 Pain in thoracic spine-Cervical	0.000	0.998	0.002
M54.61 Pain in thoracic spine-Occipit-atl-axl	0.000	0.998	0.002
M54.60 Pain in thoracic spine (Multiple sites in spine)	0.000	0.998	0.002
M54.8 Other dorsalgia	0.000	0.998	0.002
D89.0 Polyclonal hypergammaglobulinaemia	0.002	0.998	0.000
M54.1 Radiculopathy	0.000	0.998	0.002
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.000	0.998	0.002
H54.3 Unqualified visual loss, both eyes	0.002	0.998	0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified	0.000	0.998	0.002
S62.5 Fracture of thumb	0.000	0.998	0.002
C25.8 Overlapping lesion of pancreas	0.002	0.998	0.000
I44.2 Atrioventricular block, complete	0.000	0.998	0.002
M53.2 Spinal instabilities	0.000	0.998	0.002
M53.1 Cervicobrachial syndrome	0.000	0.998	0.002
M53.0 Cervicocranial syndrome	0.000	0.998	0.002
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.000	0.998	0.002
S62.51 Fracture of thumb (open)	0.000	0.998	0.002
C25.7 Other parts of pancreas	0.002	0.998	0.000
C18.9 Colon, unspecified	0.002	0.998	0.000
M53.9 Dorsopathy, unspecified	0.000	0.998	0.002
M53.8 Other specified dorsopathies	0.000	0.998	0.002
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.998	0.002
M54.17 Radiculopathy (Lumbosacral region)	0.000	0.998	0.002
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)	0.002	0.998	0.000
M87.29 Osteonecrosis due to previous trauma (Site unspecified)	0.002	0.998	0.000
M87.28 Osteonecrosis due to previous trauma (Other)	0.002	0.998	0.000
M87.26 Osteonecrosis due to previous trauma (Lower leg)	0.002	0.998	0.000
M87.24 Osteonecrosis due to previous trauma (Hand)	0.002	0.998	0.000
M87.23 Osteonecrosis due to previous trauma (Forearm)	0.002	0.998	0.000
M87.22 Osteonecrosis due to previous trauma (Upper arm)	0.002	0.998	0.000
M87.21 Osteonecrosis due to previous trauma (Shoulder region)	0.002	0.998	0.000
O04.4 Incomplete, without complication	0.000	0.998	0.002
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.000	0.998	0.002
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.000	0.998	0.002
O03.9 Complete or unspecified, without complication	0.000	0.998	0.002
M54.19 Radiculopathy (Site unspecified)	0.000	0.998	0.002
H54.4 Blindness, one eye	0.002	0.998	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.000	0.998	0.002
C34.8 Overlapping lesion of bronchus and lung	0.000	0.998	0.002
O03.4 Incomplete, without complication	0.000	0.998	0.002
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified	0.002	0.998	0.000
M54.86 Other dorsalgia (Lumbar region)	0.000	0.998	0.002
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.000	0.998	0.002
H54.1 Blindness, one eye, low vision, other eye	0.002	0.998	0.000
Q54.9 Hypospadias, unspecified	0.002	0.998	0.000
R47.0 Dysphasia and aphasia	0.002	0.998	0.000
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)	0.002	0.998	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.000	0.998	0.002
M54.09 Panniculitis affecting regions of neck and back (Site unspecified)	0.000	0.998	0.002
M54.08 Panniculitis affecting regions of neck and back (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M54.07 Panniculitis affecting regions of neck and back (Lumbosacral region)	0.000	0.998	0.002
M54.06 Panniculitis affecting regions of neck and back (Lumbar region)	0.000	0.998	0.002
M54.05 Panniculitis affecting regions of neck and back (Thoracolumbar region)	0.000	0.998	0.002
M54.04 Panniculitis affecting regions of neck and back (Thoracic region)	0.000	0.998	0.002
M54.03 Panniculitis affecting regions of neck and back (Cervicothoracic region)	0.000	0.998	0.002
M54.02 Panniculitis affecting regions of neck and back (Cervical region)	0.000	0.998	0.002
M54.01 Panniculitis affecting regions of neck and back (Occipito-atlanto-axial region)	0.000	0.998	0.002
M54.00 Panniculitis affecting regions of neck and back (Multiple sites in spine)	0.000	0.998	0.002
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.000	0.998	0.002
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.000	0.998	0.002
B34.9 Viral infection, unspecified	0.000	0.998	0.002
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.000	0.998	0.002
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.000	0.998	0.002
M54.89 Other dorsalgia (Site unspecified)	0.000	0.998	0.002
M54.88 Other dorsalgia (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M54.87 Other dorsalgia (Lumbosacral region)	0.000	0.998	0.002
M54.85 Other dorsalgia (Thoracolumbar region)	0.000	0.998	0.002
M54.83 Other dorsalgia (Cervicothoracic region)	0.000	0.998	0.002
M54.82 Other dorsalgia (Cervical region)	0.000	0.998	0.002
M54.81 Other dorsalgia (Occipito-atlanto-axial region)	0.000	0.998	0.002
J99.8 Respiratory disorders in other diseases classified elsewhere	0.000	0.998	0.002
L91.9 Hypertrophic disorder of skin, unspecified	0.000	0.998	0.002
R61.9 Hyperhidrosis, unspecified	0.000	0.998	0.002
M54.15 Radiculopathy (Thoracolumbar region)	0.000	0.998	0.002
M54.13 Radiculopathy (Cervicothoracic region)	0.000	0.998	0.002
M54.11 Radiculopathy (Occipito-atlanto-axial region)	0.000	0.998	0.002
M54.10 Radiculopathy (Multiple sites in spine)	0.000	0.998	0.002
L98.8 Other specified disorders of skin and subcutaneous tissue	0.000	0.998	0.002
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.000	0.998	0.002
M53.37 Sacrococcygeal disorders, not elsewhere classified-Lumbosac	0.000	0.998	0.002
M53.36 Sacrococcygeal disorders, not elsewhere classified-Lumbar	0.000	0.998	0.002
M53.35 Sacrococcygeal disorders, not elsewhere classified-Thoracol	0.000	0.998	0.002
M53.34 Sacrococcygeal disorders, not elsewhere classified-Thoracic	0.000	0.998	0.002
M53.33 Sacrococcygeal disorders, not elsewhere classified-Cervicot	0.000	0.998	0.002
M53.32 Sacrococcygeal disorders, not elsewhere classified-Cervical	0.000	0.998	0.002
M53.31 Sacrococcygeal disorders, not elsewhere classified-Occipit-	0.000	0.998	0.002
M53.30 Sacrococcygeal disorders, not elsewhere classified-Mult sit	0.000	0.998	0.002
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.000	0.998	0.002
I05.0 Mitral stenosis	0.000	0.998	0.002
M53.09 Cervicocranial syndrome-Site unspe	0.000	0.998	0.002
M53.08 Cervicocranial syndrome-Sacral/sacrococ	0.000	0.998	0.002
M53.07 Cervicocranial syndrome-Lumbosacral	0.000	0.998	0.002
M53.06 Cervicocranial syndrome-Lumbar	0.000	0.998	0.002
M53.05 Cervicocranial syndrome-Thoracolumbar	0.000	0.998	0.002
M53.04 Cervicocranial syndrome-Thoracic	0.000	0.998	0.002
M53.03 Cervicocranial syndrome (Cervicothoracic region)	0.000	0.998	0.002
M53.02 Cervicocranial syndrome (Cervical region)	0.000	0.998	0.002
M53.01 Cervicocranial syndrome (Occipito-atlanto-axial region)	0.000	0.998	0.002
M53.00 Cervicocranial syndrome (Multiple sites in spine)	0.000	0.998	0.002
M53.19 Cervicobrachial syndrome-Site unspe	0.000	0.998	0.002
M53.18 Cervicobrachial syndrome-Sacral/sacrococ	0.000	0.998	0.002
M53.17 Cervicobrachial syndrome-Lumbosacral	0.000	0.998	0.002
M53.16 Cervicobrachial syndrome-Lumbar	0.000	0.998	0.002
M53.15 Cervicobrachial syndrome-Thoracolumbar	0.000	0.998	0.002
M53.14 Cervicobrachial syndrome-Thoracic	0.000	0.998	0.002
M53.13 Cervicobrachial syndrome (Cervicothoracic region)	0.000	0.998	0.002
M53.12 Cervicobrachial syndrome (Cervical region)	0.000	0.998	0.002
M53.11 Cervicobrachial syndrome (Occipito-atlanto-axial region)	0.000	0.998	0.002
M53.10 Cervicobrachial syndrome (Multiple sites in spine)	0.000	0.998	0.002
M53.29 Spinal instabilities (Site unspecified)	0.000	0.998	0.002
M53.28 Spinal instabilities (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M53.27 Spinal instabilities (Lumbosacral region)	0.000	0.998	0.002
M53.26 Spinal instabilities (Lumbar region)	0.000	0.998	0.002
M53.25 Spinal instabilities (Thoracolumbar region)	0.000	0.998	0.002
M53.24 Spinal instabilities (Thoracic region)	0.000	0.998	0.002
M53.23 Spinal instabilities (Cervicothoracic region)	0.000	0.998	0.002
M53.22 Spinal instabilities (Cervical region)	0.000	0.998	0.002
M53.21 Spinal instabilities (Occipito-atlanto-axial region)	0.000	0.998	0.002
M53.20 Spinal instabilities (Multiple sites in spine)	0.000	0.998	0.002
M53.39 Sacrococcygeal disorders, not elsewhere classified-Site uns	0.000	0.998	0.002
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.000	0.998	0.002
F22.0 Delusional disorder	0.002	0.998	0.000
O04 Medical abortion	0.000	0.998	0.002
M54.14 Radiculopathy (Thoracic region)	0.000	0.998	0.002
O03 Spontaneous abortion	0.000	0.998	0.002
M54.84 Other dorsalgia (Thoracic region)	0.000	0.998	0.002
M53.89 Other specified dorsopathies (Site unspecified)	0.000	0.998	0.002
M53.88 Other specified dorsopathies (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M53.87 Other specified dorsopathies (Lumbosacral region)	0.000	0.998	0.002
M53.86 Other specified dorsopathies (Lumbar region)	0.000	0.998	0.002
M53.85 Other specified dorsopathies (Thoracolumbar region)	0.000	0.998	0.002
M53.84 Other specified dorsopathies (Thoracic region)	0.000	0.998	0.002
M53.83 Other specified dorsopathies (Cervicothoracic region)	0.000	0.998	0.002
M53.81 Other specified dorsopathies (Occipito-atlanto-axial region)	0.000	0.998	0.002
M53.80 Other specified dorsopathies (Multiple sites in spine)	0.000	0.998	0.002
M53.99 Dorsopathy, unspecified (Site unspecified)	0.000	0.998	0.002
M53.98 Dorsopathy, unspecified (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M53.97 Dorsopathy, unspecified (Lumbosacral region)	0.000	0.998	0.002
M53.95 Dorsopathy, unspecified (Thoracolumbar region)	0.000	0.998	0.002
M53.94 Dorsopathy, unspecified (Thoracic region)	0.000	0.998	0.002
M53.93 Dorsopathy, unspecified (Cervicothoracic region)	0.000	0.998	0.002
M53.92 Dorsopathy, unspecified (Cervical region)	0.000	0.998	0.002
M53.91 Dorsopathy, unspecified (Occipito-atlanto-axial region)	0.000	0.998	0.002
M53.90 Dorsopathy, unspecified (Multiple sites in spine)	0.000	0.998	0.002
L91.0 Keloid scar	0.000	0.998	0.002
M54.80 Other dorsalgia (Multiple sites in spine)	0.000	0.998	0.002
K62.8 Other specified diseases of anus and rectum	0.002	0.998	0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities	0.002	0.998	0.000
I44 Atrioventricular and left bundle-branch block	0.000	0.998	0.002
C25.2 Tail of pancreas	0.002	0.998	0.000
S62.8 Fracture of other and unspecified parts of wrist and hand	0.000	0.998	0.002
C34.2 Middle lobe, bronchus or lung	0.000	0.998	0.002
I44.4 Left anterior fascicular block	0.000	0.998	0.002
M53.82 Other specified dorsopathies (Cervical region)	0.000	0.998	0.002
M53.96 Dorsopathy, unspecified (Lumbar region)	0.000	0.998	0.002
K61.3 Ischiorectal abscess	0.000	0.998	0.002
M23.2 Derangement of meniscus due to old tear or injury	0.000	0.998	0.002
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.000	0.998	0.002
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.000	0.998	0.002
Z46.4 Fitting and adjustment of orthodontic device	0.002	0.998	0.000
S62 Fracture at wrist and hand level	0.000	0.998	0.002
M54.96 Dorsalgia, unspecified (Lumbar region)	0.000	0.998	0.002
S62.70 Multiple fractures of fingers (closed)	0.000	0.998	0.002
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.998	0.002
N34.2 Other urethritis	0.000	0.998	0.002
M47.80 Other spondylosis (Multiple sites in spine)	0.000	0.998	0.002
O04.8 Complete or unspecified, with other and unspecified complications	0.000	0.998	0.002
O04.7 Complete or unspecified, complicated by embolism	0.000	0.998	0.002
O04.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.000	0.998	0.002
O04.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.000	0.998	0.002
O04.3 Incomplete, with other and unspecified complications	0.000	0.998	0.002
O04.2 Incomplete, complicated by embolism	0.000	0.998	0.002
O04.0 Incomplete, complicated by genital tract and pelvic infection	0.000	0.998	0.002
S79.9 Unspecified injury of hip and thigh	0.000	0.998	0.002
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
Z30.1 Insertion of (intra-uterine) contraceptive device	0.002	0.998	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.002	0.998	0.000
K12.1 Other forms of stomatitis	0.000	0.998	0.002
O03.8 Complete or unspecified, with other and unspecified complications	0.000	0.998	0.001
O03.7 Complete or unspecified, complicated by embolism	0.000	0.998	0.001
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.000	0.998	0.001
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.000	0.998	0.001
O03.2 Incomplete, complicated by embolism	0.000	0.998	0.001
O03.0 Incomplete, complicated by genital tract and pelvic infection	0.000	0.998	0.001
S62.7 Multiple fractures of fingers	0.000	0.998	0.001
B00.1 Herpesviral vesicular dermatitis	0.002	0.998	0.000
I44.5 Left posterior fascicular block	0.000	0.998	0.001
O03.3 Incomplete, with other and unspecified complications	0.000	0.998	0.001
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.000	0.998	0.001
F22.9 Persistent delusional disorder, unspecified	0.002	0.998	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.000	0.998	0.002
C34.3 Lower lobe, bronchus or lung	0.000	0.998	0.002
K59.1 Functional diarrhoea	0.002	0.998	0.000
S30.1 Contusion of abdominal wall	0.000	0.998	0.002
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.000	0.998	0.001
D23.7 Skin of lower limb, including hip	0.000	0.998	0.002
I44.6 Other and unspecified fascicular block	0.000	0.998	0.002
D63 Anaemia in chronic diseases classified elsewhere	0.002	0.998	0.000
F22 Persistent delusional disorders	0.002	0.998	0.000
M18 Arthrosis of first carpometacarpal joint	0.000	0.998	0.002
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.000	0.998	0.001
E73.9 Lactose intolerance, unspecified	0.000	0.998	0.002
I05.9 Mitral valve disease, unspecified	0.000	0.998	0.002
M77.4 Metatarsalgia	0.000	0.998	0.001
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.001	0.998	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.002	0.998	0.000
S62.1 Fracture of other carpal bone(s)	0.000	0.998	0.001
H18.2 Other corneal oedema	0.001	0.998	0.000
O41.8 Other specified disorders of amniotic fluid and membranes	0.001	0.998	0.000
Q23.0 Congenital stenosis of aortic valve	0.000	0.998	0.001
M54.18 Radiculopathy (Sacral and sacrococcygeal region)	0.000	0.998	0.001
S82.00 Fracture of patella (closed)	0.001	0.998	0.000
Y83.9 Surgical procedure, unspecified	0.000	0.998	0.002
R72 Abnormality of white blood cells, not elsewhere classified	0.002	0.998	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia	0.001	0.999	0.000
O03.1 Incomplete, complicated by delayed or excessive haemorrhage	0.000	0.999	0.001
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.000	0.999	0.001
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.000	0.999	0.001
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters	0.001	0.999	0.000
C92.0 Acute myeloid leukaemia	0.000	0.999	0.001
I05.2 Mitral stenosis with insufficiency	0.000	0.999	0.001
Z73.9 Problem related to life-management difficulty, unspecified	0.001	0.999	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.999	0.001
S69.8 Other specified injuries of wrist and hand	0.001	0.999	0.000
I05 Rheumatic mitral valve diseases	0.000	0.999	0.001
F22.8 Other persistent delusional disorders	0.001	0.999	0.000
F23.3 Other acute predominantly delusional psychotic disorders	0.001	0.999	0.000
H80.9 Otosclerosis, unspecified	0.001	0.999	0.000
K62.3 Rectal prolapse	0.001	0.999	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.001	0.999	0.000
M77.49 Metatarsalgia-Site unspec	0.000	0.999	0.001
M77.48 Metatarsalgia-Other	0.000	0.999	0.001
M77.46 Metatarsalgia-Lower Leg	0.000	0.999	0.001
M77.45 Metatarsalgia-Pelvic/Thigh	0.000	0.999	0.001
M77.44 Metatarsalgia-Hand	0.000	0.999	0.001
M77.43 Metatarsalgia-Forearm	0.000	0.999	0.001
M77.42 Metatarsalgia-Upper arm	0.000	0.999	0.001
M77.41 Metatarsalgia-Shldr region	0.000	0.999	0.001
M77.40 Metatarsalgia-Mult sites	0.000	0.999	0.001
D63.1 Anaemia in other chronic diseases classified elsewhere	0.001	0.999	0.000
K55.1 Chronic vascular disorders of intestine	0.000	0.999	0.001
K65.9 Peritonitis, unspecified	0.001	0.999	0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.000	0.999	0.001
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.000	0.999	0.001
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.000	0.999	0.001
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.000	0.999	0.001
N34.3 Urethral syndrome, unspecified	0.000	0.999	0.001
Q50.4 Embryonic cyst of Fallopian tube	0.000	0.999	0.001
S62.2 Fracture of first metacarpal bone	0.000	0.999	0.001
S69.9 Unspecified injury of wrist and hand	0.001	0.999	0.000
M54.55 Low back pain (Thoracolumbar region)	0.000	0.999	0.001
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.001	0.999	0.000
S62.11 Fracture of other carpal bone(s) (open)	0.000	0.999	0.001
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.001	0.999	0.000
S62.4 Multiple fractures of metacarpal bones	0.000	0.999	0.001
F23 Acute and transient psychotic disorders	0.001	0.999	0.000
K55 Vascular disorders of intestine	0.000	0.999	0.001
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.001	0.999	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.000	0.999	0.001
S62.10 Fracture of other carpal bone(s) (closed)	0.000	0.999	0.001
Y76.2 Prosthetic and other implants, materials and accessory devices	0.001	0.999	0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung	0.000	0.999	0.001
M80.88 Other osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.001	0.999	0.000
S62.0 Fracture of navicular [scaphoid] bone of hand	0.000	0.999	0.001
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.001	0.999	0.000
S92.40 Fracture of great toe (closed)	0.001	0.999	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.001	0.999	0.000
E06.9 Thyroiditis, unspecified	0.000	0.999	0.001
F23.9 Acute and transient psychotic disorder, unspecified	0.001	0.999	0.000
I05.8 Other mitral valve diseases	0.000	0.999	0.001
M80.8 Other osteoporosis with pathological fracture	0.001	0.999	0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.000	0.999	0.001
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.001	0.999	0.000
S62.21 Fracture of first metacarpal bone (open)	0.000	0.999	0.001
D11.9 Major salivary gland, unspecified	0.001	0.999	0.000
I27.9 Pulmonary heart disease, unspecified	0.000	0.999	0.001
I27.0 Primary pulmonary hypertension	0.000	0.999	0.001
I61.9 Intracerebral haemorrhage, unspecified	0.000	0.999	0.001
M80 Osteoporosis with pathological fracture	0.001	0.999	0.000
Q54 Hypospadias	0.001	0.999	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.001	0.999	0.000
C16.0 Cardia	0.000	0.999	0.001
H18.5 Hereditary corneal dystrophies	0.001	0.999	0.000
I61.8 Other intracerebral haemorrhage	0.000	0.999	0.001
M54.5 Low back pain	0.000	0.999	0.001
N90.5 Atrophy of vulva	0.000	0.999	0.001
T13.0 Superficial injury of lower limb, level unspecified	0.001	0.999	0.000
S62.41 Multiple fractures of metacarpal bones (open)	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations