TreeWAS – Variant ID: rs12901001

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H52.1 Myopia	0.118	0.882	0.000
H52 Disorders of refraction and accommodation	0.109	0.891	0.000
H52.3 Anisometropia and aniseikonia	0.105	0.895	0.000
H52.4 Presbyopia	0.086	0.914	0.000
H52.7 Disorder of refraction, unspecified	0.084	0.916	0.000
H52.6 Other disorders of refraction	0.078	0.921	0.000
H52.5 Disorders of accommodation	0.078	0.921	0.000
H52.2 Astigmatism	0.073	0.927	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.072	0.928	0.000
H49 Paralytic strabismus	0.069	0.931	0.000
H52.0 Hypermetropia	0.065	0.935	0.000
H49.2 Sixth [abducent] nerve palsy	0.062	0.938	0.000
H49.0 Third [oculomotor] nerve palsy	0.059	0.941	0.000
H51 Other disorders of binocular movement	0.056	0.944	0.000
H49.9 Paralytic strabismus, unspecified	0.054	0.946	0.000
H49.8 Other paralytic strabismus	0.053	0.946	0.000
H49.4 Progressive external ophthalmoplegia	0.052	0.948	0.000
H49.3 Total (external) ophthalmoplegia	0.050	0.950	0.000
H49.1 Fourth [trochlear] nerve palsy	0.049	0.951	0.000
H51.8 Other specified disorders of binocular movement	0.045	0.955	0.000
H51.2 Internuclear ophthalmoplegia	0.043	0.956	0.000
H51.1 Convergence insufficiency and excess	0.040	0.959	0.000
H51.0 Palsy of conjugate gaze	0.040	0.959	0.000
H51.9 Disorder of binocular movement, unspecified	0.038	0.962	0.000
N41.9 Inflammatory disease of prostate, unspecified	0.000	0.976	0.024
S72.00 Fracture of neck of femur (closed)	0.022	0.978	0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.019	0.981	0.000
M54.99 Dorsalgia, unspecified (Site unspecified)	0.015	0.985	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.014	0.986	0.000
M54.9 Dorsalgia, unspecified	0.013	0.987	0.000
A41.5 Septicaemia due to other Gram-negative organisms	0.000	0.987	0.013
H50 Other strabismus	0.012	0.988	0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.012	0.988	0.000
T82.4 Mechanical complication of vascular dialysis catheter	0.012	0.988	0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.012	0.988	0.000
T82.1 Mechanical complication of cardiac electronic device	0.012	0.988	0.000
H59.8 Other postprocedural disorders of eye and adnexa	0.000	0.988	0.012
Z43.6 Attention to other artificial openings of urinary tract	0.012	0.988	0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.011	0.989	0.000
S72.0 Fracture of neck of femur	0.011	0.989	0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.011	0.989	0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.011	0.989	0.000
N41 Inflammatory diseases of prostate	0.000	0.989	0.011
M54.96 Dorsalgia, unspecified (Lumbar region)	0.011	0.989	0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.010	0.990	0.000
H50.2 Vertical strabismus	0.009	0.990	0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.009	0.990	0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)	0.009	0.991	0.000
M54.94 Dorsalgia, unspecified (Thoracic region)	0.009	0.991	0.000
K58.9 Irritable bowel syndrome without diarrhoea	0.009	0.991	0.000
H50.8 Other specified strabismus	0.009	0.991	0.000
H50.3 Intermittent heterotropia	0.009	0.991	0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.009	0.991	0.000
N41.1 Chronic prostatitis	0.000	0.991	0.009
H50.4 Other and unspecified heterotropia	0.008	0.991	0.000
S72.01 Fracture of neck of femur (open)	0.008	0.992	0.000
H50.6 Mechanical strabismus	0.008	0.992	0.000
G20 Parkinson's disease	0.000	0.992	0.008
N41.2 Abscess of prostate	0.000	0.992	0.008
C18.0 Caecum	0.008	0.992	0.000
N41.8 Other inflammatory diseases of prostate	0.000	0.992	0.008
T82.3 Mechanical complication of other vascular grafts	0.008	0.992	0.000
H50.0 Convergent concomitant strabismus	0.008	0.992	0.000
N41.3 Prostatocystitis	0.000	0.992	0.008
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.008	0.992	0.000
H50.5 Heterophoria	0.008	0.992	0.000
Z43 Attention to artificial openings	0.008	0.992	0.000
Z43.1 Attention to gastrostomy	0.007	0.993	0.000
T82.0 Mechanical complication of heart valve prosthesis	0.007	0.993	0.000
Z43.3 Attention to colostomy	0.007	0.993	0.000
G25 Other extrapyramidal and movement disorders	0.000	0.993	0.007
M54.92 Dorsalgia, unspecified (Cervical region)	0.006	0.994	0.000
C18.2 Ascending colon	0.006	0.994	0.000
N41.0 Acute prostatitis	0.000	0.994	0.006
G20-G26 Extrapyramidal and movement disorders	0.000	0.994	0.006
G25.9 Extrapyramidal and movement disorder, unspecified	0.000	0.994	0.006
G25.3 Myoclonus	0.000	0.994	0.006
Z43.8 Attention to other artificial openings	0.006	0.994	0.000
Z43.4 Attention to other artificial openings of digestive tract	0.006	0.994	0.000
G25.2 Other specified forms of tremor	0.000	0.994	0.006
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.006	0.994	0.000
G25.8 Other specified extrapyramidal and movement disorders	0.000	0.994	0.006
Z43.9 Attention to unspecified artificial opening	0.006	0.994	0.000
Z43.7 Attention to artificial vagina	0.006	0.994	0.000
C18 Malignant neoplasm of colon	0.006	0.994	0.000
G25.5 Other chorea	0.000	0.994	0.005
G25.1 Drug-induced tremor	0.000	0.995	0.005
Z43.5 Attention to cyctostomy	0.005	0.995	0.000
Z43.0 Attention to tracheostomy	0.005	0.995	0.000
M54.47 Lumbago with sciatica (Lumbosacral region)	0.005	0.995	0.000
G23 Other degenerative diseases of basal ganglia	0.000	0.995	0.005
G25.6 Drug-induced tics and other tics of organic origin	0.000	0.995	0.005
G25.4 Drug-induced chorea	0.000	0.995	0.005
H50.9 Strabismus, unspecified	0.005	0.995	0.000
C18.5 Splenic flexure	0.005	0.995	0.000
G83.4 Cauda equina syndrome	0.005	0.995	0.000
G83.1 Monoplegia of lower limb	0.005	0.995	0.000
E14.9 Without complications	0.005	0.995	0.000
C18.8 Overlapping lesion of colon	0.005	0.995	0.000
M54.4 Lumbago with sciatica	0.005	0.995	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.000	0.995	0.004
G22 Parkinsonism in diseases classified elsewhere	0.000	0.995	0.004
C18.9 Colon, unspecified	0.004	0.996	0.000
G83 Other paralytic syndromes	0.004	0.996	0.000
G23.8 Other specified degenerative diseases of basal ganglia	0.000	0.996	0.004
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]	0.000	0.996	0.004
G30.9 Alzheimer's disease, unspecified	0.004	0.996	0.000
C18.1 Appendix	0.004	0.996	0.000
G83.8 Other specified paralytic syndromes	0.004	0.996	0.000
C18.7 Sigmoid colon	0.004	0.996	0.000
G23.9 Degenerative disease of basal ganglia, unspecified	0.000	0.996	0.004
G23.3 Multiple system atrophy, cerebellar type	0.000	0.996	0.004
G23.2 Striatonigral degeneration	0.000	0.996	0.004
G23.0 Hallervorden-Spatz disease	0.000	0.996	0.004
Z90.0 Acquired absence of part of head and neck	0.000	0.996	0.004
G21 Secondary Parkinsonism	0.000	0.996	0.004
E85.9 Amyloidosis, unspecified	0.000	0.996	0.004
Z72.1 Alcohol use	0.004	0.996	0.000
G83.9 Paralytic syndrome, unspecified	0.004	0.996	0.000
M54.49 Lumbago with sciatica (Site unspecified)	0.004	0.996	0.000
M54.46 Lumbago with sciatica (Lumbar region)	0.004	0.996	0.000
C18.4 Transverse colon	0.004	0.996	0.000
M54 Dorsalgia	0.004	0.996	0.000
E14 Unspecified diabetes mellitus	0.004	0.996	0.000
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)	0.003	0.996	0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)	0.003	0.996	0.000
M54.44 Lumbago with sciatica-Thoracic	0.003	0.996	0.000
M54.43 Lumbago with sciatica-Cervicothoracic	0.003	0.996	0.000
M54.42 Lumbago with sciatica-Cervical	0.003	0.996	0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl	0.003	0.996	0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)	0.003	0.996	0.000
E14.3 With ophthalmic complications	0.004	0.996	0.000
G25.0 Essential tremor	0.000	0.996	0.003
G83.5 Locked-in syndrome	0.003	0.997	0.000
G83.3 Monoplegia, unspecified	0.003	0.997	0.000
G83.0 Diplegia of upper limbs	0.003	0.997	0.000
G30.0 Alzheimer's disease with early onset	0.003	0.997	0.000
S72 Fracture of femur	0.003	0.997	0.000
S72.90 Fracture of femur, part unspecified (closed)	0.003	0.997	0.000
C18.6 Descending colon	0.003	0.997	0.000
S72.9 Fracture of femur, part unspecified	0.003	0.997	0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.000	0.997	0.003
E14.1 With ketoacidosis	0.003	0.997	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.003	0.997	0.000
G21.9 Secondary Parkinsonism, unspecified	0.000	0.997	0.003
M54.19 Radiculopathy (Site unspecified)	0.003	0.997	0.000
G21.8 Other secondary Parkinsonism	0.000	0.997	0.003
G21.4 Vascular parkinsonism	0.000	0.997	0.003
G21.3 Postencephalitic Parkinsonism	0.000	0.997	0.003
G21.2 Secondary Parkinsonism due to other external agents	0.000	0.997	0.003
G24 Dystonia	0.000	0.997	0.003
G30 Alzheimer's disease	0.003	0.997	0.000
M54.0 Panniculitis affecting regions of neck and back	0.003	0.997	0.000
E14.6 With other specified complications	0.003	0.997	0.000
H50.1 Divergent concomitant strabismus	0.003	0.997	0.000
C18.3 Hepatic flexure	0.003	0.997	0.000
E14.7 With multiple complications	0.003	0.997	0.000
E14.5 With peripheral circulatory complications	0.003	0.997	0.000
I86.1 Scrotal varices	0.003	0.997	0.000
M76.67 Achilles tendinitis (Ankle and foot)	0.000	0.997	0.003
E14.2 Withrenal complications	0.003	0.997	0.000
S70.1 Contusion of thigh	0.003	0.997	0.000
M54.1 Radiculopathy	0.003	0.997	0.000
K91.3 Postoperative intestinal obstruction	0.003	0.997	0.000
G21.1 Other drug-induced secondary Parkinsonism	0.000	0.997	0.003
G21.0 Malignant neuroleptic syndrome	0.000	0.997	0.002
M54.6 Pain in thoracic spine	0.003	0.997	0.000
Z01.4 Gynaecological examination (general)(routine)	0.000	0.997	0.003
G58.9 Mononeuropathy, unspecified	0.000	0.997	0.003
M54.8 Other dorsalgia	0.003	0.997	0.000
C34.1 Upper lobe, bronchus or lung	0.000	0.997	0.003
E14.0 With coma	0.003	0.997	0.000
I31.3 Pericardial effusion (noninflammatory)	0.003	0.997	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.003	0.997	0.000
E14.4 With neurological complications	0.003	0.997	0.000
G83.2 Monoplegia of upper limb	0.002	0.997	0.000
M76.66 Achilles tendinitis (Lower leg)	0.000	0.997	0.003
E14.8 With unspecified complications	0.002	0.997	0.000
S72.91 Fracture of femur, part unspecified (open)	0.002	0.997	0.000
C49.6 Connective and soft tissue of trunk, unspecified	0.000	0.997	0.003
S72.7 Multiple fractures of femur	0.002	0.997	0.000
E10.1 With ketoacidosis	0.003	0.997	0.000
G24.0 Drug-induced dystonia	0.000	0.997	0.002
M54.29 Cervicalgia-Site unspe	0.003	0.997	0.000
M54.12 Radiculopathy (Cervical region)	0.003	0.997	0.000
G24.3 Spasmodic torticollis	0.000	0.997	0.002
C49.4 Connective and soft tissue of abdomen	0.000	0.997	0.002
G24.4 Idiopathic orofacial dystonia	0.000	0.997	0.002
G24.2 Idiopathic nonfamilial dystonia	0.000	0.997	0.002
S72.8 Fractures of other parts of femur	0.002	0.997	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.000	0.998	0.002
M54.87 Other dorsalgia (Lumbosacral region)	0.002	0.998	0.000
M54.2 Cervicalgia	0.002	0.998	0.000
M54.10 Radiculopathy (Multiple sites in spine)	0.002	0.998	0.000
C77.9 Lymph node, unspecified	0.002	0.998	0.000
M67.2 Synovial hypertrophy, not elsewhere classified	0.002	0.998	0.000
M54.09 Panniculitis affecting regions of neck and back (Site unspecified)	0.002	0.998	0.000
M54.08 Panniculitis affecting regions of neck and back (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M54.07 Panniculitis affecting regions of neck and back (Lumbosacral region)	0.002	0.998	0.000
M54.06 Panniculitis affecting regions of neck and back (Lumbar region)	0.002	0.998	0.000
M54.05 Panniculitis affecting regions of neck and back (Thoracolumbar region)	0.002	0.998	0.000
M54.04 Panniculitis affecting regions of neck and back (Thoracic region)	0.002	0.998	0.000
M54.03 Panniculitis affecting regions of neck and back (Cervicothoracic region)	0.002	0.998	0.000
M54.02 Panniculitis affecting regions of neck and back (Cervical region)	0.002	0.998	0.000
M54.01 Panniculitis affecting regions of neck and back (Occipito-atlanto-axial region)	0.002	0.998	0.000
M54.00 Panniculitis affecting regions of neck and back (Multiple sites in spine)	0.002	0.998	0.000
M76.6 Achilles tendinitis	0.000	0.998	0.002
S71.1 Open wound of thigh	0.002	0.998	0.000
C49 Malignant neoplasm of other connective and soft tissue	0.000	0.998	0.002
M54.13 Radiculopathy (Cervicothoracic region)	0.002	0.998	0.000
O24 Diabetes mellitus in pregnancy	0.002	0.998	0.000
C62.9 Testis, unspecified	0.002	0.998	0.000
R40.2 Coma, unspecified	0.002	0.998	0.000
K58 Irritable bowel syndrome	0.002	0.998	0.000
Z43.2 Attention to ileostomy	0.002	0.998	0.000
M54.15 Radiculopathy (Thoracolumbar region)	0.002	0.998	0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)	0.002	0.998	0.000
M54.63 Pain in thoracic spine (Cervicothoracic region)	0.002	0.998	0.000
H59.0 Vitreous syndrome following cataract surgery	0.000	0.998	0.002
M54.69 Pain in thoracic spine-Site unspe	0.002	0.998	0.000
M54.68 Pain in thoracic spine-Sacral/sacrococ	0.002	0.998	0.000
M54.67 Pain in thoracic spine-Lumbosacral	0.002	0.998	0.000
M54.66 Pain in thoracic spine-Lumbar	0.002	0.998	0.000
M54.65 Pain in thoracic spine (Thoracolumbar region)	0.002	0.998	0.000
M54.62 Pain in thoracic spine-Cervical	0.002	0.998	0.000
M54.61 Pain in thoracic spine-Occipit-atl-axl	0.002	0.998	0.000
M54.60 Pain in thoracic spine (Multiple sites in spine)	0.002	0.998	0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M54.86 Other dorsalgia (Lumbar region)	0.002	0.998	0.000
M54.85 Other dorsalgia (Thoracolumbar region)	0.002	0.998	0.000
M54.83 Other dorsalgia (Cervicothoracic region)	0.002	0.998	0.000
M54.82 Other dorsalgia (Cervical region)	0.002	0.998	0.000
M54.81 Other dorsalgia (Occipito-atlanto-axial region)	0.002	0.998	0.000
G24.8 Other dystonia	0.000	0.998	0.002
Z94.0 Kidney transplant status	0.002	0.998	0.000
G24.9 Dystonia, unspecified	0.000	0.998	0.002
M54.89 Other dorsalgia (Site unspecified)	0.002	0.998	0.000
C49.3 Connective and soft tissue of thorax	0.000	0.998	0.002
G71.0 Muscular dystrophy	0.000	0.998	0.002
M54.23 Cervicalgia (Cervicothoracic region)	0.002	0.998	0.000
S71 Open wound of hip and thigh	0.002	0.998	0.000
S70 Superficial injury of hip and thigh	0.002	0.998	0.000
M54.80 Other dorsalgia (Multiple sites in spine)	0.002	0.998	0.000
H60.9 Otitis externa, unspecified	0.002	0.998	0.000
S72.2 Subtrochanteric fracture	0.002	0.998	0.000
G24.1 Idiopathic familial dystonia	0.000	0.998	0.002
S32.50 Fracture of pubis (closed)	0.000	0.998	0.002
G30.8 Other Alzheimer's disease	0.002	0.998	0.000
G30.1 Alzheimer's disease with late onset	0.002	0.998	0.000
A46 Erysipelas	0.000	0.998	0.002
M54.14 Radiculopathy (Thoracic region)	0.002	0.998	0.000
S72.71 Multiple fractures of femur (open)	0.002	0.998	0.000
S72.3 Fracture of shaft of femur	0.002	0.998	0.000
C49.2 Connective and soft tissue of lower limb, including hip	0.000	0.998	0.002
M70.65 Trochanteric bursitis-Pelvic/Thigh	0.002	0.998	0.000
S72.81 Fractures of other parts of femur (open)	0.002	0.998	0.000
H59.9 Postprocedural disorder of eye and adnexa, unspecified	0.000	0.998	0.002
M54.27 Cervicalgia-Lumbosacral	0.002	0.998	0.000
M54.26 Cervicalgia-Lumbar	0.002	0.998	0.000
M54.25 Cervicalgia-Thoracolumbar	0.002	0.998	0.000
M54.24 Cervicalgia-Thoracic	0.002	0.998	0.000
M54.20 Cervicalgia-Mult site	0.002	0.998	0.000
M54.84 Other dorsalgia (Thoracic region)	0.002	0.998	0.000
S83.2 Tear of meniscus, current	0.000	0.998	0.002
M54.64 Pain in thoracic spine (Thoracic region)	0.002	0.998	0.000
S72.70 Multiple fractures of femur (closed)	0.002	0.998	0.000
S70-S79 Injuries to the hip and thigh	0.002	0.998	0.000
M54.88 Other dorsalgia (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M76.69 Achilles tendinitis-Site unspec	0.000	0.998	0.002
M76.68 Achilles tendinitis-Other	0.000	0.998	0.002
M76.65 Achilles tendinitis-Pelvic/Thigh	0.000	0.998	0.002
M76.64 Achilles tendinitis-Hand	0.000	0.998	0.002
M76.63 Achilles tendinitis-Forearm	0.000	0.998	0.002
M76.62 Achilles tendinitis-Upper arm	0.000	0.998	0.002
M76.61 Achilles tendinitis-Shldr region	0.000	0.998	0.002
M76.60 Achilles tendinitis (Multiple sites)	0.000	0.998	0.002
C49.9 Connective and soft tissue, unspecified	0.000	0.998	0.002
C49.8 Overlapping lesion of connective and soft tissue	0.000	0.998	0.002
C49.0 Connective and soft tissue of head, face and neck	0.000	0.998	0.002
G24.5 Blepharospasm	0.000	0.998	0.002
O24.3 Pre-existing diabetes mellitus, unspecified	0.002	0.998	0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.002	0.998	0.000
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.002	0.998	0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)	0.002	0.998	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.000	0.998	0.002
C49.1 Connective and soft tissue of upper limb, including shoulder	0.000	0.998	0.002
S71.0 Open wound of hip	0.002	0.998	0.000
S70.0 Contusion of hip	0.002	0.998	0.000
S72.4 Fracture of lower end of femur	0.001	0.998	0.001
O24.9 Diabetes mellitus in pregnancy, unspecified	0.002	0.998	0.000
Z97.5 Presence of (intra-uterine) contraceptive device	0.002	0.998	0.000
S72.1 Pertrochanteric fracture	0.002	0.998	0.000
E85 Amyloidosis	0.000	0.998	0.002
C49.5 Connective and soft tissue of pelvis	0.000	0.998	0.002
F11.2 Dependence syndrome	0.002	0.998	0.000
R40.0 Somnolence	0.002	0.998	0.000
E10-E14 Diabetes mellitus	0.002	0.998	0.000
M54.28 Cervicalgia-Sacral/sacrococ	0.002	0.998	0.000
S72.80 Fractures of other parts of femur (closed)	0.002	0.998	0.000
A87.9 Viral meningitis, unspecified	0.002	0.998	0.000
S71.8 Open wound of other and unspecified parts of pelvic girdle	0.002	0.998	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.000	0.998	0.002
S72.21 Subtrochanteric fracture (open)	0.002	0.998	0.000
S72.31 Fracture of shaft of femur (open)	0.002	0.998	0.000
E10.5 With peripheral circulatory complications	0.002	0.998	0.000
L85.8 Other specified epidermal thickening	0.002	0.998	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.000	0.998	0.002
E10 Insulin-dependent diabetes mellitus	0.002	0.998	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.000	0.998	0.002
G31.9 Degenerative disease of nervous system, unspecified	0.002	0.998	0.000
S70.8 Other superficial injuries of hip and thigh	0.002	0.998	0.000
S70.7 Multiple superficial injuries of hip and thigh	0.002	0.998	0.000
S71.7 Multiple open wounds of of hip and thigh	0.002	0.998	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.002	0.998	0.000
I86.8 Varicose veins of other specified sites	0.002	0.998	0.000
E10.6 With other specified complications	0.002	0.998	0.000
E85.3 Secondary systemic amyloidosis	0.000	0.998	0.002
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.002	0.998	0.000
S78 Traumatic amputation of hip and thigh	0.002	0.998	0.000
S77 Crushing injury of hip and thigh	0.002	0.998	0.000
E10.8 With unspecified complications	0.002	0.998	0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.002	0.998	0.000
M70.56 Other bursitis of knee-Lower Leg	0.002	0.998	0.000
R40 Somnolence, stupor and coma	0.002	0.998	0.000
S74 Injury of nerves at hip and thigh level	0.002	0.998	0.000
S75 Injury of blood vessels at hip and thigh level	0.002	0.998	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.998	0.002
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.998	0.002
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.998	0.002
G57.8 Other mononeuropathies of lower limb	0.000	0.998	0.002
S76.4 Injury of other and unspecified muscles and tendons at thigh level	0.002	0.998	0.000
S42.10 Fracture of scapula (closed)	0.000	0.998	0.002
S72.11 Pertrochanteric fracture (open)	0.001	0.998	0.000
E85.4 Organ-limited amyloidosis	0.000	0.998	0.002
E12 Malnutrition-related diabetes mellitus	0.002	0.998	0.000
G71.1 Myotonic disorders	0.000	0.998	0.002
M54.3 Sciatica	0.002	0.998	0.000
E13 Other specified diabetes mellitus	0.002	0.998	0.000
M54.17 Radiculopathy (Lumbosacral region)	0.001	0.998	0.000
B18.2 Chronic viral hepatitis C	0.002	0.998	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.000	0.998	0.002
Q66.8 Other congenital deformities of feet	0.000	0.998	0.002
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.000	0.998	0.002
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.002	0.998	0.000
E10.2 With renal complications	0.002	0.998	0.000
E85.8 Other amyloidosis	0.000	0.998	0.001
R59.9 Enlarged lymph nodes, unspecified	0.000	0.998	0.002
E10.7 With multiple complications	0.001	0.998	0.000
M70.6 Trochanteric bursitis	0.002	0.998	0.000
R40.1 Stupor	0.001	0.998	0.000
S76.1 Injury of quadriceps muscle and tendon	0.001	0.998	0.000
S76.7 Injury of multiple muscles and tendons at hip and thigh level	0.001	0.998	0.000
S76.2 Injury of adductor muscle and tendon of thigh	0.001	0.998	0.000
S76.0 Injury of muscle and tendon of hip	0.001	0.998	0.000
S72.41 Fracture of lower end of femur (open)	0.001	0.998	0.001
G30-G32 Other degenerative diseases of the nervous system	0.002	0.998	0.000
S76.3 Injury of muscle and tendon of the posterior muscle group at thigh level	0.001	0.998	0.000
Y40.9 Systemic antibiotic, unspecified	0.002	0.998	0.000
S77.2 Crushing injury of hip with thigh	0.001	0.998	0.000
S77.1 Crushing injury of thigh	0.001	0.998	0.000
S77.0 Crushing injury of hip	0.001	0.998	0.000
S78.9 Traumatic amputation of hip and thigh, level unspecified	0.001	0.998	0.000
S78.1 Traumatic amputation at level between hip and knee	0.001	0.998	0.000
S78.0 Traumatic amputation at hip joint	0.001	0.998	0.000
E11.5 With peripheral circulatory complications	0.002	0.998	0.000
S74.9 Injury of unspecified nerve at hip and thigh level	0.001	0.998	0.000
S74.8 Injury of other nerves at hip and thigh level	0.001	0.998	0.000
S74.7 Injury of multiple nerves at hip and thigh level	0.001	0.998	0.000
S74.2 Injury of cutaneous sensory nerve at hip and thigh level	0.001	0.998	0.000
S74.1 Injury of femoral nerve at hip and thigh level	0.001	0.998	0.000
I86 Varicose veins of other sites	0.002	0.998	0.000
S75.9 Injury of unspecified blood vessel at hip and thigh level	0.001	0.998	0.000
S75.8 Injury of other blood vessels at hip and thigh level	0.001	0.998	0.000
S75.7 Injury of multiple blood vessels at hip and thigh level	0.001	0.998	0.000
S75.2 Injury of greater saphenous vein at hip and thigh level	0.001	0.998	0.000
S75.1 Injury of femoral vein at hip and thigh level	0.001	0.998	0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.001	0.998	0.000
S74.0 Injury of sciatic nerve at hip and thigh level	0.001	0.999	0.000
E12.9 Without complications	0.001	0.999	0.000
E12.8 With unspecified complications	0.001	0.999	0.000
E12.7 With multiple complications	0.001	0.999	0.000
E12.6 With other specified complications	0.001	0.999	0.000
E12.5 With peripheral circulatory complications	0.001	0.999	0.000
E12.4 With neurological complications	0.001	0.999	0.000
E12.3 With ophthalmic complications	0.001	0.999	0.000
E12.2 With renal complications	0.001	0.999	0.000
E12.1 With ketoacidosis	0.001	0.999	0.000
E12.0 With coma	0.001	0.999	0.000
G00.9 Bacterial meningitis, unspecified	0.001	0.999	0.000
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.001	0.999	0.000
I80.8 Phlebitis and thrombophlebitis of other sites	0.000	0.999	0.001
S51.0 Open wound of elbow	0.001	0.999	0.000
M54.35 Sciatica (Thoracolumbar region)	0.001	0.999	0.000
M54.34 Sciatica-Thoracic	0.001	0.999	0.000
M54.33 Sciatica-Cervicothoracic	0.001	0.999	0.000
M54.32 Sciatica-Cervical	0.001	0.999	0.000
M54.31 Sciatica-Occipit-atl-axl	0.001	0.999	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.000	0.999	0.001
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.000	0.999	0.001
E13.8 With unspecified complications	0.001	0.999	0.000
E13.7 With multiple complications	0.001	0.999	0.000
E13.6 With other specified complications	0.001	0.999	0.000
E13.5 With peripheral circulatory complications	0.001	0.999	0.000
E13.4 With neurological complications	0.001	0.999	0.000
E13.3 With ophthalmic complications	0.001	0.999	0.000
E13.2 With renal complications	0.001	0.999	0.000
E13.1 With ketoacidosis	0.001	0.999	0.000
E13.0 With coma	0.001	0.999	0.000
S75.0 Injury of femoral artery	0.001	0.999	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.001	0.999	0.000
E10.3 With ophthalmic complications	0.001	0.999	0.000
N25.8 Other disorders resulting from impaired renal tubular function	0.001	0.999	0.000
U80.1 Methicillin resistant agent	0.001	0.999	0.000
G71 Primary disorders of muscles	0.000	0.999	0.001
M70.5 Other bursitis of knee	0.001	0.999	0.000
M06.34 Rheumatoid nodule (Hand)	0.000	0.999	0.001
M70.68 Trochanteric bursitis-Other	0.001	0.999	0.000
M70.67 Trochanteric bursitis-Ankle/Foot	0.001	0.999	0.000
M70.66 Trochanteric bursitis-Lower Leg	0.001	0.999	0.000
M70.64 Trochanteric bursitis-Hand	0.001	0.999	0.000
M70.63 Trochanteric bursitis-Forearm	0.001	0.999	0.000
M70.62 Trochanteric bursitis-Upper arm	0.001	0.999	0.000
M70.61 Trochanteric bursitis-Shldr region	0.001	0.999	0.000
M70.60 Trochanteric bursitis-Mult sites	0.001	0.999	0.000
S76.10 Unspecified injury of quadriceps muscle, fascia and tendon	0.001	0.999	0.000
H60.1 Cellulitis of external ear	0.001	0.999	0.000
M70.32 Other bursitis of elbow-Upper arm	0.001	0.999	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.000	0.999	0.001
E13.9 Without complications	0.001	0.999	0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.001	0.999	0.000
Y84.2 Radiological procedure and radiotherapy	0.001	0.999	0.000
M70.69 Trochanteric bursitis-Site unspec	0.001	0.999	0.000
S72.40 Fracture of lower end of femur (closed)	0.000	0.999	0.001
C51.9 Vulva, unspecified	0.000	0.999	0.001
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.999	0.001
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.001	0.999	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.000	0.999	0.001
S72.20 Subtrochanteric fracture (closed)	0.001	0.999	0.000
C71.1 Frontal lobe	0.001	0.999	0.000
E11.6 With other specified complications	0.001	0.999	0.000
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere	0.001	0.999	0.000
I86.0 Sublingual varices	0.001	0.999	0.000
Q07.0 Arnold-Chiari syndrome	0.001	0.999	0.000
R52.1 Chronic intractable pain	0.001	0.999	0.000
M54.30 Sciatica (Multiple sites in spine)	0.001	0.999	0.000
B02.2 Zoster with other nervous system involvement	0.001	0.999	0.000
D07.1 Vulva	0.000	0.999	0.001
I86.2 Pelvic varices	0.001	0.999	0.000
J93.1 Other spontaneous pneumothorax	0.000	0.999	0.001
A41 Other septicaemia	0.000	0.999	0.001
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.001	0.999	0.000
M24.07 Loose body in joint (Ankle and foot)	0.000	0.999	0.001
B18.9 Chronic viral hepatitis, unspecified	0.001	0.999	0.000
G71.9 Primary disorder of muscle, unspecified	0.000	0.999	0.001
G71.8 Other primary disorders of muscles	0.000	0.999	0.001
G71.2 Congenital myopathies	0.000	0.999	0.001
J33.0 Polyp of nasal cavity	0.000	0.999	0.001
E11 Non-insulin-dependent diabetes mellitus	0.001	0.999	0.000
M70.04 Chronic crepitant synovitis of hand and wrist (Hand)	0.001	0.999	0.000
M70.59 Other bursitis of knee-Site unspec	0.001	0.999	0.000
M70.58 Other bursitis of knee-Other	0.001	0.999	0.000
M70.57 Other bursitis of knee-Ankle/Foot	0.001	0.999	0.000
M70.55 Other bursitis of knee-Pelvic/Thigh	0.001	0.999	0.000
M70.54 Other bursitis of knee-Hand	0.001	0.999	0.000
M70.53 Other bursitis of knee-Forearm	0.001	0.999	0.000
M70.52 Other bursitis of knee-Upper arm	0.001	0.999	0.000
M70.51 Other bursitis of knee-Shldr region	0.001	0.999	0.000
M70.50 Other bursitis of knee-Mult sites	0.001	0.999	0.000
B18.1 Chronic viral hepatitis B without delta-agent	0.001	0.999	0.000
S32.5 Fracture of pubis	0.000	0.999	0.001
B18 Chronic viral hepatitis	0.001	0.999	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.001	0.999	0.000
I31.9 Disease of pericardium, unspecified	0.001	0.999	0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.000	0.999	0.001
S70.9 Superficial injury of hip and thigh, unspecified	0.001	0.999	0.000
Z01.2 Dental examination	0.000	0.999	0.001
M49.54 Collapsed vertebra in diseases classified elsewhere (Thoracic region)	0.000	0.999	0.001
A41.0 Septicaemia due to Staphylococcus aureus	0.000	0.999	0.001
M70.3 Other bursitis of elbow	0.001	0.999	0.000
S10.9 Superficial injury of neck, part unspecified	0.001	0.999	0.000
M94.88 Other specified disorders of cartilage (Other)	0.001	0.999	0.000
E10.4 With neurological complications	0.001	0.999	0.000
E10.0 With coma	0.001	0.999	0.000
G00.3 Staphylococcal meningitis	0.001	0.999	0.000
A41.3 Septicaemia due to Haemophilus influenzae	0.000	0.999	0.001
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.000	0.999	0.001
D84.9 Immunodeficiency, unspecified	0.000	0.999	0.001
E11.2 With renal complications	0.001	0.999	0.000
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.001	0.999	0.000
G12.2 Motor neuron disease	0.001	0.999	0.000
M70.0 Chronic crepitant synovitis of hand and wrist	0.001	0.999	0.000
I31 Other diseases of pericardium	0.001	0.999	0.000
E11.7 With multiple complications	0.001	0.999	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.001	0.999	0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.001	0.999	0.000
S79 Other and unspecified injuries of hip and thigh	0.001	0.999	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.001	0.999	0.000
S32.51 Fracture of pubis (open)	0.000	0.999	0.001
A41.4 Septicaemia due to anaerobes	0.000	0.999	0.001
B18.8 Other chronic viral hepatitis	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations