TreeWAS – Variant ID: rs12940923

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
S82.40 Fracture of fibula alone (closed)	0.029	0.971	0.000
S82.4 Fracture of fibula alone	0.026	0.974	0.000
S82.10 Fracture of upper end of tibia (closed)	0.026	0.974	0.000
S82.1 Fracture of upper end of tibia	0.025	0.975	0.000
D22.7 Melanocytic naevi of lower limb, including hip	0.000	0.975	0.025
S82 Fracture of lower leg, including ankle	0.024	0.976	0.000
S82.11 Fracture of upper end of tibia (open)	0.022	0.978	0.000
S82.6 Fracture of lateral malleolus	0.020	0.980	0.000
S82.2 Fracture of shaft of tibia	0.020	0.980	0.000
S82.3 Fracture of lower end of tibia	0.019	0.981	0.000
S82.41 Fracture of fibula alone (open)	0.019	0.981	0.000
S82.0 Fracture of patella	0.018	0.982	0.000
S82.9 Fracture of lower leg, part unspecified	0.018	0.982	0.000
S82.5 Fracture of medial malleolus	0.017	0.983	0.000
S82.60 Fracture of lateral malleolus (closed)	0.017	0.983	0.000
S82.20 Fracture of shaft of tibia (closed)	0.016	0.984	0.000
S82.7 Multiple fractures of lower leg	0.015	0.984	0.000
H73.8 Other specified disorders of tympanic membrane	0.000	0.985	0.015
S82.30 Fracture of lower end of tibia (closed)	0.015	0.985	0.000
S82.31 Fracture of lower end of tibia (open)	0.015	0.985	0.000
S82.61 Fracture of lateral malleolus (open)	0.014	0.985	0.000
S82.21 Fracture of shaft of tibia (open)	0.014	0.986	0.000
S82.00 Fracture of patella (closed)	0.014	0.986	0.000
S82.01 Fracture of patella (open)	0.014	0.986	0.000
S82.91 Fracture of lower leg, part unspecified (open)	0.013	0.987	0.000
S82.90 Fracture of lower leg, part unspecified (closed)	0.013	0.987	0.000
S82.51 Fracture of medial malleolus (open)	0.012	0.987	0.000
S82.50 Fracture of medial malleolus (closed)	0.012	0.988	0.000
H73 Other disorders of tympanic membrane	0.000	0.988	0.012
S82.71 Multiple fractures of lower leg (open)	0.011	0.988	0.000
S82.8 Fractures of other parts of lower leg	0.011	0.989	0.000
F41.2 Mixed anxiety and depressive disorder	0.000	0.990	0.010
H65-H75 Diseases of middle ear and mastoid	0.000	0.990	0.010
S82.70 Multiple fractures of lower leg (closed)	0.009	0.990	0.000
M84.0 Malunion of fracture	0.009	0.991	0.000
M84.03 Malunion of fracture (Forearm)	0.009	0.991	0.000
J34.3 Hypertrophy of nasal turbinates	0.009	0.991	0.000
L81.9 Disorder of pigmentation, unspecified	0.000	0.991	0.009
H74 Other disorders of middle ear and mastoid	0.000	0.991	0.009
H73.1 Chronic myringitis	0.000	0.991	0.009
H73.0 Acute myringitis	0.000	0.991	0.009
H73.9 Disorder of tympanic membrane, unspecified	0.000	0.991	0.009
H66 Suppurative and unspecified otitis media	0.000	0.991	0.009
M84.07 Malunion of fracture (Ankle and foot)	0.009	0.991	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.000	0.992	0.008
H61.0 Perichondritis of external ear	0.000	0.992	0.008
M84.01 Malunion of fracture (Shoulder region)	0.008	0.992	0.000
S82.86 Maisonneuve's fracture	0.008	0.992	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.000	0.992	0.008
H66.3 Other chronic suppurative otitis media	0.000	0.992	0.008
H71 Cholesteatoma of middle ear	0.000	0.992	0.008
H66.1 Chronic tubotympanic suppurative otitis media	0.000	0.992	0.008
M84.04 Malunion of fracture (Hand)	0.008	0.992	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.007	0.993	0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities	0.000	0.993	0.007
H74.0 Tympanosclerosis	0.000	0.993	0.007
H26.4 After-cataract	0.007	0.993	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.993	0.007
H68 Eustachian salpingitis and obstruction	0.000	0.993	0.007
H67 Otitis media in diseases classified elsewhere	0.000	0.993	0.007
H80.9 Otosclerosis, unspecified	0.000	0.993	0.007
M84.09 Malunion of fracture (Site unspecified)	0.007	0.993	0.000
M84.08 Malunion of fracture (Other)	0.007	0.993	0.000
M84.00 Malunion of fracture (Multiple sites)	0.007	0.993	0.000
H66.4 Suppurative otitis media, unspecified	0.000	0.993	0.007
M35.3 Polymyalgia rheumatica	0.000	0.993	0.007
M81.90 Osteoporosis, unspecified (Multiple sites)	0.007	0.993	0.000
Chapter VIII Diseases of the ear and mastoid process	0.000	0.993	0.007
M84.02 Malunion of fracture (Upper arm)	0.007	0.993	0.000
H74.1 Adhesive middle ear disease	0.000	0.993	0.007
M84.06 Malunion of fracture (Lower leg)	0.007	0.993	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.000	0.993	0.007
H66.0 Acute suppurative otitis media	0.000	0.993	0.007
H74.2 Discontinuity and dislocation of ear ossicles	0.000	0.993	0.007
H61 Other disorders of external ear	0.000	0.993	0.007
M84 Disorders of continuity of bone	0.007	0.993	0.000
H60-H62 Diseases of external ear	0.000	0.993	0.007
S82.81 Fractures of other parts of lower leg (open)	0.006	0.993	0.000
H70 Mastoiditis and related conditions	0.000	0.993	0.006
H74.9 Disorder of middle ear and mastoid, unspecified	0.000	0.994	0.006
I35.1 Aortic (valve) insufficiency	0.006	0.994	0.000
H69 Other disorders of Eustachian tube	0.000	0.994	0.006
H80 Otosclerosis	0.000	0.994	0.006
L71.9 Rosacea, unspecified	0.006	0.994	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.006	0.994	0.000
D22 Melanocytic naevi	0.000	0.994	0.006
D22.6 Melanocytic naevi of upper limb, including shoulder	0.000	0.994	0.006
H80-H83 Diseases of inner ear	0.000	0.994	0.006
K91.4 Colostomy and enterostomy malfunction	0.000	0.994	0.006
H66.9 Otitis media, unspecified	0.000	0.994	0.006
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.006	0.994	0.000
H72 Perforation of tympanic membrane	0.000	0.994	0.006
M06.0 Seronegative rheumatoid arthritis	0.006	0.994	0.000
M81.9 Osteoporosis, unspecified	0.006	0.994	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.000	0.995	0.005
H67.1 Otitis media in viral diseases classified elsewhere	0.000	0.995	0.005
H67.0 Otitis media in bacterial diseases classified elsewhere	0.000	0.995	0.005
H68.1 Obstruction of Eustachian tube	0.000	0.995	0.005
H68.0 Eustachian salpingitis	0.000	0.995	0.005
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.995	0.005
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.000	0.995	0.005
M81 Osteoporosis without pathological fracture	0.005	0.995	0.000
D22.0 Melanocytic naevi of lip	0.000	0.995	0.005
H69.8 Other specified disorders of Eustachian tube	0.000	0.995	0.005
H61.9 Disorder of external ear, unspecified	0.000	0.995	0.005
M84.2 Delayed union of fracture	0.005	0.995	0.000
Z87.0 Personal history of diseases of the respiratory system	0.000	0.995	0.005
S82.80 Fractures of other parts of lower leg (closed)	0.005	0.995	0.000
M84.9 Disorder of continuity of bone, unspecified	0.005	0.995	0.000
M84.8 Other disorders of continuity of bone	0.005	0.995	0.000
M84.3 Stress fracture, not elsewhere classified	0.005	0.995	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.000	0.995	0.005
H70.8 Other mastoiditis and related conditions	0.000	0.995	0.005
H70.2 Petrositis	0.000	0.995	0.005
H70.1 Chronic mastoiditis	0.000	0.995	0.005
H70.0 Acute mastoiditis	0.000	0.995	0.005
M81.2 Osteoporosis of disuse	0.005	0.995	0.000
H61.8 Other specified disorders of external ear	0.000	0.995	0.005
M81.96 Osteoporosis, unspecified (Lower leg)	0.005	0.995	0.000
H69.0 Patulous Eustachian tube	0.000	0.995	0.005
H80.8 Other otosclerosis	0.000	0.995	0.005
H80.2 Cochlear otosclerosis	0.000	0.995	0.005
H80.1 Otosclerosis involving oval window, obliterative	0.000	0.995	0.005
H80.0 Otosclerosis involving oval window, nonobliterative	0.000	0.995	0.005
H60 Otitis externa	0.000	0.995	0.005
M80-M85 Disorders of bone density and structure	0.005	0.995	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.005	0.995	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.005	0.995	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.005	0.995	0.000
D22.9 Melanocytic naevi, unspecified	0.000	0.995	0.005
H90.3 Sensorineural hearing loss, bilateral	0.000	0.995	0.005
M81.20 Osteoporosis of disuse (Multiple sites)	0.005	0.995	0.000
M84.4 Pathological fracture, not elsewhere classified	0.005	0.995	0.000
H72.2 Other marginal perforations of tympanic membrane	0.000	0.995	0.004
M82 Osteoporosis in diseases classified elsewhere	0.005	0.995	0.000
D22.4 Melanocytic naevi of scalp and neck	0.000	0.995	0.005
G93.4 Encephalopathy, unspecified	0.000	0.995	0.005
H90-H95 Other disorders of ear	0.000	0.995	0.005
H72.1 Attic perforation of tympanic membrane	0.000	0.995	0.004
H82 Vertiginous syndromes in diseases classified elsewhere	0.000	0.995	0.004
M82.1 Osteoporosis in endocrine disorders	0.004	0.995	0.000
H60.1 Cellulitis of external ear	0.000	0.996	0.004
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.004	0.996	0.000
O14.9 Preeclampsia, unspecified	0.000	0.996	0.004
D22.1 Melanocytic naevi of eyelid, including canthus	0.000	0.996	0.004
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.004	0.996	0.000
H74.4 Polyp of middle ear	0.000	0.996	0.004
M06.08 Seronegative rheumatoid arthritis (Other)	0.004	0.996	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.004	0.996	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.004	0.996	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.004	0.996	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.004	0.996	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.004	0.996	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.004	0.996	0.000
H83 Other diseases of inner ear	0.000	0.996	0.004
S91.3 Open wound of other parts of foot	0.000	0.996	0.004
Z30.5 Surveillance of (intra-uterine) contraceptive device	0.000	0.996	0.004
H90 Conductive and sensorineural hearing loss	0.000	0.996	0.004
M81.94 Osteoporosis, unspecified (Hand)	0.004	0.996	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.004	0.996	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.004	0.996	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.004	0.996	0.000
H61.2 Impacted cerumen	0.000	0.996	0.004
H70.9 Mastoiditis, unspecified	0.000	0.996	0.004
M81.0 Postmenopausal osteoporosis	0.004	0.996	0.000
H61.1 Non-infective disorders of pinna	0.000	0.996	0.004
H61.3 Acquired stenosis of external ear canal	0.000	0.996	0.004
H72.9 Perforation of tympanic membrane, unspecified	0.000	0.996	0.004
M81.8 Other osteoporosis	0.004	0.996	0.000
M81.6 Localised osteoporosis [Lequesne]	0.004	0.996	0.000
M81.5 Idiopathic osteoporosis	0.004	0.996	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.004	0.996	0.000
M81.1 Postoophorectomy osteoporosis	0.004	0.996	0.000
H92 Otalgia and effusion of ear	0.000	0.996	0.004
M84.26 Delayed union of fracture (Lower leg)	0.004	0.996	0.000
H65 Nonsuppurative otitis media	0.000	0.996	0.004
M84.29 Delayed union of fracture (Site unspecified)	0.004	0.996	0.000
M84.28 Delayed union of fracture (Other)	0.004	0.996	0.000
M84.27 Delayed union of fracture (Ankle and foot)	0.004	0.996	0.000
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.004	0.996	0.000
M84.24 Delayed union of fracture (Hand)	0.004	0.996	0.000
M84.23 Delayed union of fracture (Forearm)	0.004	0.996	0.000
M84.22 Delayed union of fracture (Upper arm)	0.004	0.996	0.000
M84.21 Delayed union of fracture (Shoulder region)	0.004	0.996	0.000
M84.20 Delayed union of fracture (Multiple sites)	0.004	0.996	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.004	0.996	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.004	0.996	0.000
H90.0 Conductive hearing loss, bilateral	0.000	0.996	0.004
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.004	0.996	0.000
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.004	0.996	0.000
M84.38 Stress fracture, not elsewhere classified (Other)	0.004	0.996	0.000
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.004	0.996	0.000
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.004	0.996	0.000
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.004	0.996	0.000
M84.34 Stress fracture, not elsewhere classified (Hand)	0.004	0.996	0.000
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.004	0.996	0.000
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.004	0.996	0.000
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.004	0.996	0.000
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.004	0.996	0.000
M84.89 Other disorders of continuity of bone (Site unspecified)	0.004	0.996	0.000
M84.88 Other disorders of continuity of bone (Other)	0.004	0.996	0.000
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.004	0.996	0.000
M84.86 Other disorders of continuity of bone (Lower leg)	0.004	0.996	0.000
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.004	0.996	0.000
M84.84 Other disorders of continuity of bone (Hand)	0.004	0.996	0.000
M84.83 Other disorders of continuity of bone (Forearm)	0.004	0.996	0.000
M84.82 Other disorders of continuity of bone (Upper arm)	0.004	0.996	0.000
M84.81 Other disorders of continuity of bone (Shoulder region)	0.004	0.996	0.000
M84.80 Other disorders of continuity of bone (Multiple sites)	0.004	0.996	0.000
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.004	0.996	0.000
M84.98 Disorder of continuity of bone, unspecified (Other)	0.004	0.996	0.000
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.004	0.996	0.000
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.004	0.996	0.000
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.004	0.996	0.000
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.004	0.996	0.000
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.004	0.996	0.000
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.004	0.996	0.000
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.004	0.996	0.000
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.004	0.996	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.000	0.996	0.004
H62.4 Otitis externa in other diseases classified elsewhere	0.000	0.996	0.004
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.000	0.996	0.004
H62.2 Otitis externa in mycoses	0.000	0.996	0.004
H62.1 Otitis externa in viral diseases classified elsewhere	0.000	0.996	0.004
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.000	0.996	0.004
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.996	0.004
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.004	0.996	0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.004	0.996	0.000
H65.2 Chronic serous otitis media	0.000	0.996	0.004
M81.29 Osteoporosis of disuse (Site unspecified)	0.004	0.996	0.000
M81.28 Osteoporosis of disuse (Other)	0.004	0.996	0.000
M81.27 Osteoporosis of disuse (Ankle and foot)	0.004	0.996	0.000
M81.26 Osteoporosis of disuse (Lower leg)	0.004	0.996	0.000
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.004	0.996	0.000
M81.24 Osteoporosis of disuse (Hand)	0.004	0.996	0.000
M81.23 Osteoporosis of disuse (Forearm)	0.004	0.996	0.000
M81.22 Osteoporosis of disuse (Upper arm)	0.004	0.996	0.000
M81.21 Osteoporosis of disuse (Shoulder region)	0.004	0.996	0.000
H60.8 Other otitis externa	0.000	0.996	0.004
H92.1 Otorrhoea	0.000	0.996	0.004
M81.4 Drug-induced osteoporosis	0.004	0.996	0.000
H60.4 Cholesteatoma of external ear	0.000	0.996	0.004
H60.2 Malignant otitis externa	0.000	0.996	0.004
H60.0 Abscess of external ear	0.000	0.996	0.004
M83 Adult osteomalacia	0.004	0.996	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.004	0.996	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.004	0.996	0.000
J33.8 Other polyp of sinus	0.000	0.996	0.004
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.003	0.996	0.000
D22.2 Melanocytic naevi of ear and external auricular canal	0.000	0.996	0.004
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.004	0.996	0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.003	0.996	0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.003	0.996	0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.003	0.996	0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.003	0.996	0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.003	0.996	0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.003	0.996	0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.003	0.996	0.000
H60.5 Acute otitis externa, non-infective	0.000	0.996	0.003
H60.3 Other infective otitis externa	0.000	0.996	0.003
M82.8 Osteoporosis in other diseases classified elsewhere	0.003	0.996	0.000
M82.0 Osteoporosis in multiple myelomatosis	0.003	0.996	0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.003	0.996	0.000
T23.0 Burn of unspecified degree of wrist and hand	0.004	0.996	0.000
S91.1 Open wound of toe(s) without damage to nail	0.000	0.996	0.004
H94 Other disorders of ear in diseases classified elsewhere	0.000	0.996	0.003
M62.80 Other specified disorders of muscle (Multiple sites)	0.004	0.996	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.000	0.996	0.003
M82.19 Osteoporosis in endocrine disorders (Site unspecified)	0.003	0.996	0.000
M82.18 Osteoporosis in endocrine disorders (Other)	0.003	0.996	0.000
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)	0.003	0.996	0.000
M82.16 Osteoporosis in endocrine disorders (Lower leg)	0.003	0.996	0.000
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)	0.003	0.996	0.000
M82.14 Osteoporosis in endocrine disorders (Hand)	0.003	0.996	0.000
M82.13 Osteoporosis in endocrine disorders (Forearm)	0.003	0.996	0.000
M82.12 Osteoporosis in endocrine disorders (Upper arm)	0.003	0.996	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.000	0.996	0.003
H72.8 Other perforations of tympanic membrane	0.000	0.997	0.003
H92.0 Otalgia	0.000	0.997	0.003
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.003	0.997	0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.003	0.997	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.003	0.997	0.000
D61.9 Aplastic anaemia, unspecified	0.000	0.997	0.003
H69.9 Eustachian tube disorder, unspecified	0.000	0.997	0.003
H83.9 Disease of inner ear, unspecified	0.000	0.997	0.003
H83.8 Other specified diseases of inner ear	0.000	0.997	0.003
H83.3 Noise effects on inner ear	0.000	0.997	0.003
H83.2 Labyrinthine dysfunction	0.000	0.997	0.003
H83.1 Labyrinthine fistula	0.000	0.997	0.003
M81.08 Postmenopausal osteoporosis (Other)	0.003	0.997	0.000
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.06 Postmenopausal osteoporosis (Lower leg)	0.003	0.997	0.000
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.04 Postmenopausal osteoporosis (Hand)	0.003	0.997	0.000
M81.03 Postmenopausal osteoporosis (Forearm)	0.003	0.997	0.000
M81.02 Postmenopausal osteoporosis (Upper arm)	0.003	0.997	0.000
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.003	0.997	0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.003	0.997	0.000
S91 Open wound of ankle and foot	0.000	0.997	0.003
L81 Other disorders of pigmentation	0.000	0.997	0.003
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.003	0.997	0.000
M81.18 Postoophorectomy osteoporosis (Other)	0.003	0.997	0.000
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.003	0.997	0.000
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.14 Postoophorectomy osteoporosis (Hand)	0.003	0.997	0.000
M81.13 Postoophorectomy osteoporosis (Forearm)	0.003	0.997	0.000
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.003	0.997	0.000
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.003	0.997	0.000
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.003	0.997	0.000
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.003	0.997	0.000
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.003	0.997	0.000
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.003	0.997	0.000
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.003	0.997	0.000
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.003	0.997	0.000
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.003	0.997	0.000
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.003	0.997	0.000
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.003	0.997	0.000
M81.59 Idiopathic osteoporosis (Site unspecified)	0.003	0.997	0.000
M81.58 Idiopathic osteoporosis (Other)	0.003	0.997	0.000
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.56 Idiopathic osteoporosis (Lower leg)	0.003	0.997	0.000
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.54 Idiopathic osteoporosis (Hand)	0.003	0.997	0.000
M81.53 Idiopathic osteoporosis (Forearm)	0.003	0.997	0.000
M81.52 Idiopathic osteoporosis (Upper arm)	0.003	0.997	0.000
M81.51 Idiopathic osteoporosis (Shoulder region)	0.003	0.997	0.000
M81.50 Idiopathic osteoporosis (Multiple sites)	0.003	0.997	0.000
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.003	0.997	0.000
M81.68 Localized osteoporosis [Lequesne] (Other)	0.003	0.997	0.000
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.003	0.997	0.000
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.003	0.997	0.000
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.003	0.997	0.000
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.003	0.997	0.000
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.003	0.997	0.000
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.003	0.997	0.000
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.003	0.997	0.000
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.003	0.997	0.000
M81.89 Other osteoporosis (Site unspecified)	0.003	0.997	0.000
M81.88 Other osteoporosis (Other)	0.003	0.997	0.000
M81.87 Other osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.86 Other osteoporosis (Lower leg)	0.003	0.997	0.000
M81.85 Other osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.84 Other osteoporosis (Hand)	0.003	0.997	0.000
M81.83 Other osteoporosis (Forearm)	0.003	0.997	0.000
M81.82 Other osteoporosis (Upper arm)	0.003	0.997	0.000
M81.81 Other osteoporosis (Shoulder region)	0.003	0.997	0.000
M81.80 Other osteoporosis (Multiple sites)	0.003	0.997	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.003	0.997	0.000
Q38.7 Pharyngeal pouch	0.000	0.997	0.003
F41 Other anxiety disorders	0.000	0.997	0.003
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.000	0.997	0.003
M06 Other rheumatoid arthritis	0.003	0.997	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.000	0.997	0.003
I35 Nonrheumatic aortic valve disorders	0.003	0.997	0.000
I35.9 Aortic valve disorder, unspecified	0.003	0.997	0.000
M07.3 Other psoriatic arthropathies	0.003	0.997	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.997	0.003
H83.0 Labyrinthitis	0.000	0.997	0.003
T23 Burn and corrosion of wrist and hand	0.003	0.997	0.000
T23.2 Burn of second degree of wrist and hand	0.003	0.997	0.000
M81.48 Drug-induced osteoporosis (Other)	0.003	0.997	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.003	0.997	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.003	0.997	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.003	0.997	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.003	0.997	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.003	0.997	0.000
E83.4 Disorders of magnesium metabolism	0.000	0.997	0.003
M07.30 Other psoriatic arthropathies (Multiple sites)	0.003	0.997	0.000
E53.8 Deficiency of other specified B group vitamins	0.000	0.997	0.003
M83.9 Adult osteomalacia, unspecified	0.003	0.997	0.000
M83.8 Other adult osteomalacia	0.003	0.997	0.000
M83.5 Other drug-induced osteomalacia in adults	0.003	0.997	0.000
M83.4 Aluminum bone disease	0.003	0.997	0.000
M83.3 Adult osteomalacia due to malnutrition	0.003	0.997	0.000
M83.2 Adult osteomalacia due to malabsorption	0.003	0.997	0.000
M83.1 Senile osteomalacia	0.003	0.997	0.000
M83.0 Puerperal osteomalacia	0.003	0.997	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.003	0.997	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.003	0.997	0.000
F41.1 Generalised anxiety disorder	0.000	0.997	0.003
M07.36 Other psoriatic arthropathies (Lower leg)	0.003	0.997	0.000
M81.49 Drug-induced osteoporosis (Site unspecified)	0.003	0.997	0.000
H92.2 Otorrhagia	0.000	0.997	0.003
E89.0 Postprocedural hypothyroidism	0.003	0.997	0.000
H65.4 Other chronic nonsuppurative otitis media	0.000	0.997	0.003
H72.0 Central perforation of tympanic membrane	0.000	0.997	0.003
M82.09 Osteoporosis in multiple myelomatosis (Site unspecified)	0.003	0.997	0.000
M82.08 Osteoporosis in multiple myelomatosis (Other)	0.003	0.997	0.000
M82.07 Osteoporosis in multiple myelomatosis (Ankle and foot)	0.003	0.997	0.000
M82.06 Osteoporosis in multiple myelomatosis (Lower leg)	0.003	0.997	0.000
M82.05 Osteoporosis in multiple myelomatosis (Pelvic region and thigh)	0.003	0.997	0.000
M82.04 Osteoporosis in multiple myelomatosis (Hand)	0.003	0.997	0.000
M82.03 Osteoporosis in multiple myelomatosis (Forearm)	0.003	0.997	0.000
M82.02 Osteoporosis in multiple myelomatosis (Upper arm)	0.003	0.997	0.000
M82.01 Osteoporosis in multiple myelomatosis (Shoulder region)	0.003	0.997	0.000
M82.00 Osteoporosis in multiple myelomatosis (Multiple sites)	0.003	0.997	0.000
M82.89 Osteoporosis in other diseases classified elsewhere (Site unspecified)	0.003	0.997	0.000
M82.88 Osteoporosis in other diseases classified elsewhere (Other)	0.003	0.997	0.000
M82.87 Osteoporosis in other diseases classified elsewhere (Ankle and foot)	0.003	0.997	0.000
M82.86 Osteoporosis in other diseases classified elsewhere (Lower leg)	0.003	0.997	0.000
M82.85 Osteoporosis in other diseases classified elsewhere (Pelvic region and thigh)	0.003	0.997	0.000
M82.84 Osteoporosis in other diseases classified elsewhere (Hand)	0.003	0.997	0.000
M82.83 Osteoporosis in other diseases classified elsewhere (Forearm)	0.003	0.997	0.000
M82.82 Osteoporosis in other diseases classified elsewhere (Upper arm)	0.003	0.997	0.000
M82.81 Osteoporosis in other diseases classified elsewhere (Shoulder region)	0.003	0.997	0.000
M82.80 Osteoporosis in other diseases classified elsewhere (Multiple sites)	0.003	0.997	0.000
H65.1 Other acute nonsuppurative otitis media	0.000	0.997	0.003
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.000	0.997	0.003
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.000	0.997	0.003
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.003	0.997	0.000
G47.9 Sleep disorder, unspecified	0.000	0.997	0.003
C85.1 B-cell lymphoma, unspecified	0.000	0.997	0.003
S91.0 Open wound of ankle	0.000	0.997	0.003
M07 Psoriatic and enteropathic arthropathies	0.003	0.997	0.000
L81.8 Other specified disorders of pigmentation	0.000	0.997	0.003
M11.26 Other chondrocalcinosis (Lower leg)	0.003	0.997	0.000
M06.3 Rheumatoid nodule	0.003	0.997	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.003	0.997	0.000
M62.8 Other specified disorders of muscle	0.003	0.997	0.000
H65.0 Acute serous otitis media	0.000	0.997	0.002
S91.7 Multiple open wounds of ankle and foot	0.000	0.997	0.003
S91.2 Open wound of toe(s) with damage to nail	0.000	0.997	0.003
T23.3 Burn of third degree of wrist and hand	0.003	0.997	0.000
M19.01 Primary arthrosis of other joints (Shoulder region)	0.000	0.997	0.003
I35.2 Aortic (valve) stenosis with insufficiency	0.003	0.997	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.003	0.997	0.000
H02.5 Other disorders affecting eyelid function	0.003	0.997	0.000
L81.7 Pigmented purpuric dermatosis	0.000	0.997	0.002
L81.6 Other disorders of diminished melanin formation	0.000	0.997	0.002
L81.5 Leukoderma, not elsewhere classified	0.000	0.997	0.002
L81.3 Cafe au lait spots	0.000	0.997	0.002
L81.1 Chloasma	0.000	0.997	0.002
L81.0 Postinflammatory hyperpigmentation	0.000	0.997	0.002
M85 Other disorders of bone density and structure	0.003	0.997	0.000
D22.5 Melanocytic naevi of trunk	0.000	0.997	0.003
Y86 Sequelae of other accidents	0.003	0.997	0.000
L81.2 Freckles	0.000	0.997	0.002
F41.8 Other specified anxiety disorders	0.000	0.997	0.002
F41.3 Other mixed anxiety disorders	0.000	0.997	0.002
H90.5 Sensorineural hearing loss, unspecified	0.000	0.997	0.002
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.000	0.997	0.002
H95.8 Other postprocedural disorders of ear and mastoid process	0.000	0.997	0.002
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.997	0.002
M06.8 Other specified rheumatoid arthritis	0.002	0.997	0.000
M06.2 Rheumatoid bursitis	0.002	0.997	0.000
M06.1 Adult-onset Still's disease	0.002	0.997	0.000
M11.2 Other chondrocalcinosis	0.002	0.997	0.000
M07.38 Other psoriatic arthropathies (Other)	0.002	0.997	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.002	0.997	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.002	0.997	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.002	0.997	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.002	0.997	0.000
I35.8 Other aortic valve disorders	0.002	0.997	0.000
H60.9 Otitis externa, unspecified	0.000	0.997	0.002
H95.1 Other disorders following mastoidectomy	0.000	0.997	0.002
M07.39 Other psoriatic arthropathies (Site unspecified)	0.002	0.997	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.000	0.997	0.003
M06.34 Rheumatoid nodule (Hand)	0.002	0.998	0.000
T23.7 Corrosion of third degree of wrist and hand	0.002	0.998	0.000
T23.6 Corrosion of second degree of wrist and hand	0.002	0.998	0.000
T23.5 Corrosion of first degree of wrist and hand	0.002	0.998	0.000
T23.4 Corrosion of unspecified degree of wrist and hand	0.002	0.998	0.000
T23.1 Burn of first degree of wrist and hand	0.002	0.998	0.000
M11 Other crystal arthropathies	0.002	0.998	0.000
M05-M14 Inflammatory polyarthropathies	0.002	0.998	0.000
C01 Malignant neoplasm of base of tongue	0.002	0.998	0.000
M62.81 Other specified disorders of muscle (Shoulder region)	0.002	0.998	0.000
M83.09 Puerperal osteomalacia (Site unspecified)	0.002	0.998	0.000
M83.08 Puerperal osteomalacia (Other)	0.002	0.998	0.000
M83.07 Puerperal osteomalacia (Ankle and foot)	0.002	0.998	0.000
M83.06 Puerperal osteomalacia (Lower leg)	0.002	0.998	0.000
M83.05 Puerperal osteomalacia (Pelvic region and thigh)	0.002	0.998	0.000
M83.04 Puerperal osteomalacia (Hand)	0.002	0.998	0.000
M83.03 Puerperal osteomalacia (Forearm)	0.002	0.998	0.000
M83.02 Puerperal osteomalacia (Upper arm)	0.002	0.998	0.000
M83.01 Puerperal osteomalacia (Shoulder region)	0.002	0.998	0.000
M83.00 Puerperal osteomalacia (Multiple sites)	0.002	0.998	0.000
M83.19 Senile osteomalacia (Site unspecified)	0.002	0.998	0.000
M83.18 Senile osteomalacia (Other)	0.002	0.998	0.000
M83.17 Senile osteomalacia (Ankle and foot)	0.002	0.998	0.000
M83.16 Senile osteomalacia (Lower leg)	0.002	0.998	0.000
M83.15 Senile osteomalacia (Pelvic region and thigh)	0.002	0.998	0.000
M83.14 Senile osteomalacia (Hand)	0.002	0.998	0.000
M83.13 Senile osteomalacia (Forearm)	0.002	0.998	0.000
M83.12 Senile osteomalacia (Upper arm)	0.002	0.998	0.000
M83.11 Senile osteomalacia (Shoulder region)	0.002	0.998	0.000
M83.10 Senile osteomalacia (Multiple sites)	0.002	0.998	0.000
M83.29 Adult osteomalacia due to malabsorption (Site unspecified)	0.002	0.998	0.000
M83.28 Adult osteomalacia due to malabsorption (Other)	0.002	0.998	0.000
M83.27 Adult osteomalacia due to malabsorption (Ankle and foot)	0.002	0.998	0.000
M83.26 Adult osteomalacia due to malabsorption (Lower leg)	0.002	0.998	0.000
M83.25 Adult osteomalacia due to malabsorption (Pelvic region and thigh)	0.002	0.998	0.000
M83.24 Adult osteomalacia due to malabsorption (Hand)	0.002	0.998	0.000
M83.23 Adult osteomalacia due to malabsorption (Forearm)	0.002	0.998	0.000
M83.22 Adult osteomalacia due to malabsorption (Upper arm)	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations