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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs130073
log Bayes Factor = 67.0881
Chromosome 6   position 31,111,180  (GRCh37) Explore rs130073 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
E11.9 Without complications
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.001 0.999
E05.9 Thyrotoxicosis, unspecified
0.000 0.002 0.998
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.002 0.998
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.003 0.997
G35 Multiple sclerosis
0.996 0.004 0.000
E14 Unspecified diabetes mellitus
0.000 0.006 0.994
E70-E90 Metabolic disorders
0.000 0.007 0.993
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.016 0.984
E16 Other disorders of pancreatic internal secretion
0.000 0.028 0.972
E16.2 Hypoglycaemia, unspecified
0.000 0.042 0.958
E14.9 Without complications
0.000 0.042 0.958
E10.3 With ophthalmic complications
0.000 0.048 0.952
L40.9 Psoriasis, unspecified
0.000 0.065 0.935
C83.3 Large cell (diffuse)
0.000 0.079 0.921
E14.3 With ophthalmic complications
0.000 0.081 0.919
E11.0 With coma
0.000 0.129 0.871
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.139 0.861
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.146 0.854
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.147 0.852
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.147 0.853
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.148 0.852
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.149 0.851
I25 Chronic ischaemic heart disease
0.000 0.149 0.851
E10.1 With ketoacidosis
0.000 0.152 0.848
E83 Disorders of mineral metabolism
0.836 0.153 0.011
I25.1 Atherosclerotic heart disease
0.000 0.154 0.846
E11.1 With ketoacidosis
0.000 0.164 0.836
E78.2 Mixed hyperlipidaemia
0.000 0.167 0.833
C85.1 B-cell lymphoma, unspecified
0.000 0.168 0.832
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.171 0.829
E40-E46 Malnutrition
0.000 0.187 0.813
I25.5 Ischaemic cardiomyopathy
0.000 0.189 0.811
E78.5 Hyperlipidaemia, unspecified
0.000 0.196 0.804
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.198 0.802
E10.8 With unspecified complications
0.000 0.200 0.800
I25.2 Old myocardial infarction
0.000 0.200 0.800
E07 Other disorders of thyroid
0.000 0.201 0.799
E10.6 With other specified complications
0.000 0.204 0.795
E14.5 With peripheral circulatory complications
0.000 0.207 0.793
E13 Other specified diabetes mellitus
0.000 0.209 0.791
E74 Other disorders of carbohydrate metabolism
0.000 0.210 0.790
E78.4 Other hyperlipidaemia
0.000 0.215 0.785
E79 Disorders of purine and pyrimidine metabolism
0.000 0.225 0.775
E14.4 With neurological complications
0.000 0.225 0.775
E16.1 Other hypoglycaemia
0.000 0.226 0.774
E14.1 With ketoacidosis
0.000 0.230 0.770
I20-I25 Ischaemic heart diseases
0.000 0.232 0.768
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.234 0.766
E83.3 Disorders of phosphorus metabolism
0.757 0.240 0.003
G35-G37 Demyelinating diseases of the central nervous system
0.760 0.240 0.000
E10.0 With coma
0.000 0.242 0.758
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.246 0.754
I22 Subsequent myocardial infarction
0.000 0.252 0.748
E78.1 Pure hyperglyceridaemia
0.000 0.253 0.747
E14.6 With other specified complications
0.000 0.258 0.742
E11.2 With renal complications
0.000 0.264 0.736
E78.8 Other disorders of lipoprotein metabolism
0.000 0.266 0.734
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.267 0.733
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.273 0.727
E78.6 Lipoprotein deficiency
0.000 0.281 0.719
E10.7 With multiple complications
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E03.8 Other specified hypothyroidism
0.000 0.284 0.716
E05.5 Thyroid crisis or storm
0.000 0.284 0.715
E05.4 Thyrotoxicosis factitia
0.000 0.284 0.715
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.284 0.715
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.284 0.715
E14.7 With multiple complications
0.000 0.288 0.712
E14.0 With coma
0.000 0.288 0.712
E77 Disorders of glycoprotein metabolism
0.000 0.288 0.712
E76 Disorders of glycosaminoglycan metabolism
0.000 0.288 0.712
E72 Other disorders of amino-acid metabolism
0.000 0.288 0.712
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.288 0.712
E70 Disorders of aromatic amino-acid metabolism
0.000 0.288 0.712
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.288 0.712
E11.8 With unspecified complications
0.000 0.294 0.706
E15 Nondiabetic hypoglycaemic coma
0.000 0.295 0.705
G37 Other demyelinating diseases of central nervous system
0.705 0.295 0.000
E84 Cystic fibrosis
0.000 0.299 0.701
E14.2 Withrenal complications
0.000 0.302 0.697
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.303 0.697
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.303 0.697
E16.4 Abnormal secretion of gastrin
0.000 0.303 0.697
E16.3 Increased secretion of glucagon
0.000 0.303 0.697
C82.2 Large cell, follicular
0.000 0.305 0.695
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.310 0.690
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.311 0.689
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.000 0.311 0.689
E83.9 Disorder of mineral metabolism, unspecified
0.680 0.314 0.007
E11.5 With peripheral circulatory complications
0.000 0.320 0.680
E46 Unspecified protein-energy malnutrition
0.000 0.321 0.679
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.327 0.673
E14.8 With unspecified complications
0.000 0.328 0.672
C83.7 Burkitt's tumour
0.000 0.330 0.670
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.330 0.670
C82.3 Follicular lymphoma grade IIIa
0.000 0.339 0.661
G37.9 Demyelinating disease of central nervous system, unspecified
0.659 0.341 0.000
E13.9 Without complications
0.000 0.350 0.650
K90 Intestinal malabsorption
0.000 0.354 0.646
E88 Other metabolic disorders
0.000 0.354 0.646
C82.0 Small cleaved cell, follicular
0.000 0.355 0.645
I20 Angina pectoris
0.000 0.360 0.640
E07.9 Disorder of thyroid, unspecified
0.000 0.368 0.632
E10.5 With peripheral circulatory complications
0.000 0.369 0.631
I20.9 Angina pectoris, unspecified
0.000 0.370 0.630
E10.4 With neurological complications
0.000 0.370 0.629
C86 Other specified types of T/NK-cell lymphoma
0.000 0.372 0.628
I24 Other acute ischaemic heart diseases
0.000 0.377 0.623
E03.1 Congenital hypothyroidism without goitre
0.000 0.378 0.622
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.381 0.619
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.381 0.618
E78.3 Hyperchylomicronaemia
0.000 0.382 0.617
C83.6 Undifferentiated (diffuse)
0.000 0.382 0.617
C83.5 Lymphoblastic (diffuse)
0.000 0.382 0.617
C83.4 Immunoblastic (diffuse)
0.000 0.382 0.617
C83.2 Mixed small and large cell (diffuse)
0.000 0.382 0.617
E80.6 Other disorders of bilirubin metabolism
0.000 0.388 0.612
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.388 0.611
C82.6 Cutaneous follicle centre lymphoma
0.000 0.389 0.611
C82.5 Diffuse follicle centre lymphoma
0.000 0.389 0.611
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.389 0.610
C85.0 Lymphosarcoma
0.000 0.389 0.610
I25.6 Silent myocardial ischaemia
0.000 0.390 0.610
E80.2 Other porphyria
0.000 0.391 0.609
I23 Certain current complications following acute myocardial infarction
0.000 0.392 0.608
E83.8 Other disorders of mineral metabolism
0.599 0.393 0.008
E83.2 Disorders of zinc metabolism
0.599 0.393 0.008
E83.0 Disorders of copper metabolism
0.599 0.393 0.008
E05.8 Other thyrotoxicosis
0.000 0.394 0.606
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.395 0.605
E07.8 Other specified disorders of thyroid
0.000 0.396 0.604
E80.4 Gilbert's syndrome
0.000 0.397 0.603
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.401 0.599
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.000 0.405 0.595
I22.8 Subsequent myocardial infarction of other sites
0.000 0.407 0.593
E80.1 Porphyria cutanea tarda
0.000 0.415 0.585
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.417 0.583
E45 Retarded development following protein-energy malnutrition
0.000 0.417 0.583
E43 Unspecified severe protein-energy malnutrition
0.000 0.417 0.583
E42 Marasmic kwashiorkor
0.000 0.417 0.583
E41 Nutritional marasmus
0.000 0.417 0.583
E40 Kwashiorkor
0.000 0.417 0.583
E10.2 With renal complications
0.000 0.424 0.576
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.425 0.575
E80.5 Crigler-Najjar syndrome
0.000 0.425 0.575
E80.3 Defects of catalase and peroxydase
0.000 0.425 0.575
E80.0 Hereditary erythropoietic porphyria
0.000 0.425 0.575
E07.1 Dyshormogenetic goitre
0.000 0.427 0.573
E07.0 Hypersecretion of calcitonin
0.000 0.427 0.573
G36 Other acute disseminated demyelination
0.571 0.429 0.000
E13.8 With unspecified complications
0.000 0.433 0.567
E13.7 With multiple complications
0.000 0.433 0.567
E13.6 With other specified complications
0.000 0.433 0.567
E13.5 With peripheral circulatory complications
0.000 0.433 0.567
E13.4 With neurological complications
0.000 0.433 0.567
E13.2 With renal complications
0.000 0.433 0.567
E13.1 With ketoacidosis
0.000 0.433 0.567
E13.0 With coma
0.000 0.433 0.567
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.433 0.567
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.433 0.567
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.433 0.567
E74.2 Disorders of galactose metabolism
0.000 0.433 0.567
E74.1 Disorders of fructose metabolism
0.000 0.433 0.567
E83.4 Disorders of magnesium metabolism
0.562 0.435 0.003
C94 Other leukaemias of specified cell type
0.000 0.435 0.564
G37.8 Other specified demyelinating diseases of central nervous system
0.561 0.439 0.000
C82.4 Follicular lymphoma grade IIIb
0.000 0.443 0.557
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.444 0.555
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.444 0.555
E79.1 Lesch-Nyhan syndrome
0.000 0.444 0.555
I25.4 Coronary artery aneurysm
0.000 0.446 0.554
C84.0 Mycosis fungoides
0.000 0.448 0.552
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.448 0.552
E13.3 With ophthalmic complications
0.000 0.448 0.552
C85.7 Other specified types of non-Hodgkin's lymphoma
0.000 0.451 0.549
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.457 0.543
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.474 0.526
E73 Lactose intolerance
0.001 0.483 0.516
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E74.0 Glycogen storage disease
0.000 0.486 0.514
C93 Monocytic leukaemia
0.001 0.487 0.513
C84.4 Peripheral T-cell lymphoma
0.000 0.488 0.512
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.489 0.510
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.489 0.510
E70.3 Albinism
0.000 0.489 0.510
E70.2 Disorders of tyrosine metabolism
0.000 0.489 0.510
E70.1 Other hyperphenylalaninaemias
0.000 0.489 0.510
E70.0 Classical phenylketonuria
0.000 0.489 0.510
E71.3 Disorders of fatty-acid metabolism
0.000 0.489 0.510
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.489 0.510
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.489 0.510
E71.0 Maple-syrup-urine disease
0.000 0.489 0.510
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.489 0.510
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.489 0.510
E72.5 Disorders of glycine metabolism
0.000 0.489 0.510
E72.4 Disorders of ornithine metabolism
0.000 0.489 0.510
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.489 0.510
E72.2 Disorders of urea cycle metabolism
0.000 0.489 0.510
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.489 0.510
E72.0 Disorders of amino-acid transport
0.000 0.489 0.510
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.489 0.510
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.489 0.510
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.489 0.510
E76.2 Other mucopolysaccharidoses
0.000 0.489 0.510
E76.1 Mucopolysaccharidosis, type II
0.000 0.489 0.510
E76.0 Mucopolysaccharidosis, type I
0.000 0.489 0.510
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.489 0.510
E77.8 Other disorders of glycoprotein metabolism
0.000 0.489 0.510
E77.1 Defects in glycoprotein degradation
0.000 0.489 0.510
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.489 0.510
C88 Malignant immunoproliferative diseases
0.001 0.490 0.510
K90.9 Intestinal malabsorption, unspecified
0.000 0.493 0.507
C84.5 Other and unspecified T-cell lymphomas
0.000 0.494 0.506
G37.5 Concentric sclerosis [Balo]
0.505 0.495 0.000
G37.4 Subacute necrotising myelitis
0.505 0.495 0.000
G37.2 Central pontine myelinolysis
0.505 0.495 0.000
G37.1 Central demyelination of corpus callosum
0.505 0.495 0.000
G37.0 Diffuse sclerosis
0.505 0.495 0.000
E84.8 Cystic fibrosis with other manifestations
0.000 0.497 0.502
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.497 0.502
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.497 0.502
I25.3 Aneurysm of heart
0.000 0.498 0.502
C83.1 Small cleaved cell (diffuse)
0.000 0.499 0.500
E88.8 Other specified metabolic disorders
0.000 0.501 0.499
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.501 0.498
E88.2 Lipomatosis, not elsewhere classified
0.000 0.503 0.497
C84.9 Mature T/NK-cell lymphoma, unspecified
0.000 0.506 0.494
C84.8 Cutaneous T-cell lymphoma, unspecified
0.000 0.506 0.494
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.000 0.506 0.494
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.000 0.506 0.494
C84.3 Lymphoepithelioid lymphoma
0.000 0.506 0.494
C84.2 T-zone lymphoma
0.000 0.506 0.494
C84.1 Sezary's diease
0.000 0.506 0.494
I23.8 Other current complications following acute myocardial infarction
0.000 0.506 0.494
E84.9 Cystic fibrosis, unspecified
0.000 0.509 0.491
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.509 0.491
E11.6 With other specified complications
0.000 0.512 0.488
E75.6 Lipid storage disorder, unspecified
0.000 0.519 0.480
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.519 0.480
E75.3 Sphingolipidosis, unspecified
0.000 0.519 0.480
E75.2 Other sphingolipidosis
0.000 0.519 0.480
E75.1 Other gangliosidosis
0.000 0.519 0.480
E75.0 GM2 gangliosidosis
0.000 0.519 0.480
E11.4 With neurological complications
0.000 0.521 0.479
I20.1 Angina pectoris with documented spasm
0.000 0.522 0.478
C81 Hodgkin's disease
0.000 0.524 0.476
E88.3 Tumour lysis syndrome
0.000 0.528 0.472
C86.5 Angioimmunoblastic T-cell lymphoma
0.000 0.532 0.467
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.466 0.533 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.000 0.536 0.463
K90.3 Pancreatic steatorrhoea
0.000 0.537 0.463
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.537 0.463
K90.1 Tropical sprue
0.000 0.537 0.463
E88.9 Metabolic disorder, unspecified
0.000 0.537 0.463
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.537 0.463
L40 Psoriasis
0.000 0.540 0.460
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.000 0.549 0.450
C86.4 Blastic NK-cell lymphoma
0.000 0.549 0.450
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.000 0.549 0.450
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.000 0.549 0.450
C86.1 Hepatosplenic T-cell lymphoma
0.000 0.549 0.450
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.000 0.549 0.450
K90.8 Other intestinal malabsorption
0.000 0.550 0.449
C83.0 Small cell (diffuse)
0.000 0.557 0.443
E75.5 Other lipid storage disorders
0.000 0.561 0.439
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.000 0.561 0.438
C96.8 Histiocytic sarcoma
0.000 0.561 0.438
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.561 0.438
C96.6 Unifocal Langerhans-cell histiocytosis
0.000 0.561 0.438
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.000 0.561 0.438
C96.4 Sarcoma of dendritic cells (accessory cells)
0.000 0.561 0.438
C96.3 True histiocytic lymphoma
0.000 0.561 0.438
C96.2 Malignant mast cell tumour
0.000 0.561 0.438
C96.1 Malignant histiocytosis
0.000 0.561 0.438
C96.0 Letterer-Siwe disease
0.000 0.561 0.438
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.563 0.437
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.564 0.436
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.564 0.436
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.564 0.436
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.564 0.436
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.564 0.436
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.564 0.436
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.564 0.436
G36.0 Neuromyelitis optica [Devic]
0.436 0.564 0.000
E44.1 Mild protein-energy malnutrition
0.000 0.582 0.418
E44.0 Moderate protein-energy malnutrition
0.000 0.582 0.418
E11.3 With ophthalmic complications
0.000 0.587 0.413
E83.5 Disorders of calcium metabolism
0.411 0.588 0.001
E89.4 Postprocedural ovarian failure
0.000 0.588 0.412
G36.9 Acute disseminated demyelination, unspecified
0.410 0.590 0.000
G36.8 Other specified acute disseminated demyelination
0.410 0.590 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.410 0.590 0.000
C94.7 Other specified leukaemias
0.000 0.595 0.405
C94.5 Acute myelofibrosis
0.000 0.595 0.405
C94.4 Acute panmyelosis
0.000 0.595 0.405
C94.3 Mast cell leukaemia
0.000 0.595 0.405
C94.2 Acute megakaryoblastic leukaemia
0.000 0.595 0.405
C94.1 Chronic erythraemia
0.000 0.595 0.405
C94.0 Acute erythraemia and erythroleukaemia
0.000 0.595 0.405
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.000 0.597 0.402
E85 Amyloidosis
0.001 0.600 0.400
E06 Thyroiditis
0.000 0.602 0.398
C95 Leukaemia of unspecified cell type
0.001 0.606 0.393
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.610 0.390
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.610 0.390
E89.5 Postprocedural testicular hypofunction
0.000 0.610 0.390
E89.1 Postprocedural hypoinsulinaemia
0.000 0.610 0.390
E89.3 Postprocedural hypopituitarism
0.000 0.612 0.388
C91 Lymphoid leukaemia
0.001 0.613 0.386
I24.1 Dressler's syndrome
0.000 0.615 0.385
L40.8 Other psoriasis
0.000 0.627 0.373
E73.8 Other lactose intolerance
0.001 0.629 0.370
E73.1 Secondary lactase deficiency
0.001 0.629 0.370
E73.0 Congenital lactase deficiency
0.001 0.629 0.370
C93.9 Monocytic leukaemia, unspecified
0.001 0.632 0.368
C93.7 Other monocytic leukaemia
0.001 0.632 0.368
C93.3 Juvenile myelomonocytic leukaemia
0.001 0.632 0.368
C93.2 Subacute monocytic leukaemia
0.001 0.632 0.368
C93.0 Acute monocytic leukaemia
0.001 0.632 0.368
C88.9 Malignant immunoproliferative disease, unspecified
0.001 0.634 0.365
C88.7 Other malignant immunoproliferative diseases
0.001 0.634 0.365
C88.3 Immunoproliferative small intestinal disease
0.001 0.634 0.365
C88.2 Gamma heavy chain disease
0.001 0.634 0.365
C88.1 Alpha heavy chain disease
0.001 0.634 0.365
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.001 0.642 0.358
E89.2 Postprocedural hypoparathyroidism
0.000 0.649 0.351
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.657 0.343
C81.0 Lymphocytic predominance
0.000 0.658 0.342
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.000 0.658 0.341
C81.3 Lymphocytic depletion
0.000 0.658 0.341
E65-E68 Obesity and other hyperalimentation
0.000 0.659 0.341
L40.1 Generalised pustular psoriasis
0.000 0.663 0.337
C91.9 Lymphoid leukaemia, unspecified
0.000 0.663 0.337
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.001 0.663 0.336
L40.4 Guttate psoriasis
0.000 0.665 0.335
I24.8 Other forms of acute ischaemic heart disease
0.000 0.666 0.334
C81.7 Other Hodgkin's disease
0.000 0.668 0.332
L40.2 Acrodermatitis continua
0.000 0.670 0.330
C81.2 Mixed cellularity
0.000 0.673 0.327
L40.0 Psoriasis vulgaris
0.000 0.682 0.318
C92 Myeloid leukaemia
0.000 0.683 0.316
C81.9 Hodgkin's disease, unspecified
0.000 0.688 0.312
E06.5 Other chronic thyroiditis
0.000 0.704 0.295
C81.1 Nodular sclerosis
0.000 0.712 0.288
E85.2 Heredofamilial amyloidosis, unspecified
0.001 0.713 0.287
E85.1 Neuropathic heredofamilial amyloidosis
0.001 0.713 0.287
E85.0 Nonneuropathic heredofamilial amyloidosis
0.001 0.713 0.287
E06.4 Drug-induced thyroiditis
0.000 0.714 0.285
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.714 0.285
E06.0 Acute thyroiditis
0.000 0.714 0.285
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.716 0.283
C95.7 Other leukaemia of unspecified cell type
0.001 0.717 0.282
C95.2 Subacute leukaemia of unspecified cell type
0.001 0.717 0.282
L40.3 Pustulosis palmaris et plantaris
0.000 0.720 0.280
C91.8 Mature B-cell leukaemia Burkitt-type
0.001 0.722 0.277
C91.7 Other lymphoid leukaemia
0.001 0.722 0.277
C91.6 Prolymphocytic leukaemia of T-cell type
0.001 0.722 0.277
C91.3 Prolymphocytic leukaemia
0.001 0.722 0.277
C91.2 Subacute lymphocytic leukaemia
0.001 0.722 0.277
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.727 0.273
C93.1 Chronic monocytic leukaemia
0.001 0.730 0.269
E85.8 Other amyloidosis
0.001 0.733 0.266
C91.5 Adult T-cell leukaemia
0.001 0.734 0.266
M06.9 Rheumatoid arthritis, unspecified
0.000 0.737 0.263
L40.5 Arthropathic psoriasis
0.000 0.743 0.257
E06.1 Subacute thyroiditis
0.000 0.747 0.253
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.753 0.247
C95.1 Chronic leukaemia of unspecified cell type
0.001 0.755 0.245
E67 Other hyperalimentation
0.000 0.755 0.244
E68 Sequelae of hyperalimentation
0.000 0.755 0.244
E85.4 Organ-limited amyloidosis
0.001 0.757 0.243
E85.9 Amyloidosis, unspecified
0.001 0.759 0.241
E50-E64 Other nutritional deficiencies
0.000 0.760 0.239
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.761 0.239
C91.1 Chronic lymphocytic leukaemia
0.000 0.769 0.231
C95.9 Leukaemia, unspecified
0.001 0.770 0.230
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.770 0.230
L40-L45 Papulosquamous disorders
0.000 0.773 0.227
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.000 0.773 0.227
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.000 0.773 0.227
C92.5 Acute myelomonocytic leukaemia
0.000 0.773 0.227
C92.3 Myeloid sarcoma
0.000 0.773 0.227
C92.2 Subacute myeloid leukaemia
0.000 0.773 0.227
C95.0 Acute leukaemia of unspecified cell type
0.001 0.773 0.226
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.774 0.226
E20-E35 Disorders of other endocrine glands
0.000 0.774 0.226
C92.9 Myeloid leukaemia, unspecified
0.000 0.778 0.221
C90 Multiple myeloma and malignant plasma cell neoplasms
0.037 0.782 0.181
C92.7 Other myeloid leukaemia
0.000 0.782 0.217
E85.3 Secondary systemic amyloidosis
0.001 0.784 0.216
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.786 0.214
C92.4 Acute promyelocytic leukaemia
0.000 0.786 0.213
C91.0 Acute lymphoblastic leukaemia
0.001 0.790 0.210
E28 Ovarian dysfunction
0.000 0.793 0.207
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.794 0.206
C92.1 Chronic myeloid leukaemia
0.000 0.795 0.205
E28.2 Polycystic ovarian syndrome
0.000 0.798 0.201
E06.9 Thyroiditis, unspecified
0.001 0.802 0.198
E06.3 Autoimmune thyroiditis
0.000 0.809 0.191
E65 Localised adiposity
0.000 0.812 0.188
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.816 0.184
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.816 0.184
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.816 0.184
C88.0 Waldenstrom's macroglobulinaemia
0.001 0.819 0.180
E73.9 Lactose intolerance, unspecified
0.002 0.824 0.174
E67.8 Other specified hyperalimentation
0.000 0.824 0.175
E67.3 Hypervitaminosis D
0.000 0.824 0.175
E67.2 Megavitamin-B6 syndrome
0.000 0.824 0.175
E67.1 Hypercarotenaemia
0.000 0.824 0.175
E67.0 Hypervitaminosis A
0.000 0.824 0.175
L43 Lichen planus
0.000 0.825 0.175
E24 Cushing's syndrome
0.000 0.827 0.173
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.828 0.172
E63 Other nutritional deficiencies
0.000 0.828 0.172
E50 Vitamin A deficiency
0.000 0.828 0.172
E60 Dietary zinc deficiency
0.000 0.828 0.172
E59 Dietary selenium deficiency
0.000 0.828 0.172
E54 Ascorbic acid deficiency
0.000 0.828 0.172
E52 Niacin deficiency [pellagra]
0.000 0.828 0.172
E56 Other vitamin deficiencies
0.000 0.828 0.171
L42 Pityriasis rosea
0.000 0.830 0.170
L44 Other papulosquamous disorders
0.000 0.837 0.163
L41 Parapsoriasis
0.000 0.837 0.163
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.837 0.163
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.838 0.162
E32 Diseases of thymus
0.000 0.838 0.162
E31 Polyglandular dysfunction
0.000 0.838 0.162
E30 Disorders of puberty, not elsewhere classified
0.000 0.838 0.162
E25 Adrenogenital disorders
0.000 0.838 0.162
E51 Thiamine deficiency
0.000 0.840 0.160
E26 Hyperaldosteronism
0.000 0.843 0.157
E58 Dietary calcium deficiency
0.000 0.843 0.157
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.843 0.157
C90.3 Solitary plasmacytoma
0.026 0.847 0.127
C90.1 Plasma cell leukaemia
0.026 0.847 0.127
M06 Other rheumatoid arthritis
0.000 0.847 0.153
E61 Deficiency of other nutrient elements
0.000 0.849 0.151
L43.9 Lichen planus, unspecified
0.000 0.850 0.150
E28.9 Ovarian dysfunction, unspecified
0.000 0.851 0.149
E28.8 Other ovarian dysfunction
0.000 0.851 0.149
E28.1 Androgen excess
0.000 0.851 0.149
E28.0 Oestrogen excess
0.000 0.851 0.149
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.859 0.141
M06.3 Rheumatoid nodule
0.000 0.863 0.136
E20 Hypoparathyroidism
0.000 0.866 0.134
E24.9 Cushing's syndrome, unspecified
0.000 0.866 0.134
E21.3 Hyperparathyroidism, unspecified
0.000 0.866 0.134
E29 Testicular dysfunction
0.000 0.872 0.128
E23 Hypofunction and other disorders of pituitary gland
0.000 0.873 0.127
L43.3 Subacute (active) lichen planus
0.000 0.875 0.125
L43.2 Lichenoid drug reaction
0.000 0.875 0.125
L43.1 Bullous lichen planus
0.000 0.875 0.125
L43.0 Hypertrophic lichen planus
0.000 0.875 0.125
I20.8 Other forms of angina pectoris
0.000 0.875 0.125
E24.2 Drug-induced Cushing's syndrome
0.000 0.875 0.125
E24.8 Other Cushing's syndrome
0.000 0.876 0.124
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.876 0.124
E24.3 Ectopic ACTH syndrome
0.000 0.876 0.124
E24.1 Nelson's syndrome
0.000 0.876 0.124
E24.0 Pituitary-dependent Cushing's disease
0.000 0.876 0.124
E50.9 Vitamin A deficiency, unspecified
0.000 0.876 0.123
E50.8 Other manifestations of vitamin A deficiency
0.000 0.876 0.123
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.876 0.123
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.876 0.123
E50.5 Vitamin A deficiency with night blindness
0.000 0.876 0.123

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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