TreeWAS – Variant ID: rs13088281

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I50.9 Heart failure, unspecified	0.436	0.564	0.000
I50.1 Left ventricular failure	0.430	0.570	0.000
I50 Heart failure	0.427	0.573	0.000
I50.0 Congestive heart failure	0.305	0.695	0.000
N81.1 Cystocele	0.000	0.730	0.270
N81 Female genital prolapse	0.000	0.749	0.251
N81.6 Rectocele	0.000	0.750	0.250
N81.8 Other female genital prolapse	0.000	0.785	0.215
N81.4 Uterovaginal prolapse, unspecified	0.000	0.789	0.211
N81.0 Female urethrocele	0.000	0.792	0.208
N81.3 Complete uterovaginal prolapse	0.000	0.832	0.168
N81.2 Incomplete uterovaginal prolapse	0.000	0.842	0.158
N81.9 Female genital prolapse, unspecified	0.000	0.852	0.148
K62.1 Rectal polyp	0.000	0.910	0.090
N81.5 Vaginal enterocele	0.000	0.915	0.085
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.035	0.965	0.000
N85.0 Endometrial glandular hyperplasia	0.000	0.969	0.031
L92 Granulomatous disorders of skin and subcutaneous tissue	0.030	0.970	0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.030	0.970	0.000
L92.0 Granuloma annulare	0.023	0.977	0.000
L92.8 Other granulomatous disorders of skin and subcutaneous tissue	0.022	0.978	0.000
L92.2 Granuloma faciale [eosinophilic granuloma of skin]	0.022	0.978	0.000
L92.1 Necrobiosis lipoidica, not elsewhere classified	0.022	0.978	0.000
K57.3 Diverticular disease of large intestine without perforation or abscess	0.000	0.978	0.022
K80.2 Calculus of gallbladder without cholecystitis	0.000	0.982	0.018
K80.1 Calculus of gallbladder with other cholecystitis	0.000	0.986	0.014
H04.5 Stenosis and insufficiency of lachrymal passages	0.014	0.986	0.000
K80 Cholelithiasis	0.000	0.986	0.014
H04.2 Epiphora	0.014	0.986	0.000
H04 Disorders of lachrymal system	0.013	0.987	0.000
H04.3 Acute and unspecified inflammation of lachrymal passages	0.011	0.989	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.000	0.989	0.011
K80.3 Calculus of bile duct with cholangitis	0.000	0.990	0.010
H04.8 Other disorders of lachrymal system	0.010	0.990	0.000
H04.4 Chronic inflammation of lachrymal passages	0.010	0.990	0.000
K86 Other diseases of pancreas	0.000	0.990	0.010
C54.1 Endometrium	0.000	0.990	0.010
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.000	0.990	0.010
O34.2 Maternal care due to uterine scar from previous surgery	0.010	0.990	0.000
H04.6 Other changes in lachrymal passages	0.009	0.990	0.000
H04.0 Dacryoadenitis	0.009	0.990	0.000
N19 Unspecified renal failure	0.009	0.991	0.000
K83 Other diseases of biliary tract	0.000	0.991	0.009
K83.0 Cholangitis	0.000	0.991	0.009
K86.8 Other specified diseases of pancreas	0.000	0.991	0.009
K80.0 Calculus of gallbladder with acute cholecystitis	0.000	0.991	0.009
K86.1 Other chronic pancreatitis	0.000	0.991	0.009
H93.1 Tinnitus	0.009	0.991	0.000
H04.9 Disorder of lachrymal system, unspecified	0.009	0.991	0.000
K85 Acute pancreatitis	0.000	0.991	0.009
K86.3 Pseudocyst of pancreas	0.000	0.991	0.008
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.000	0.992	0.008
K81 Cholecystitis	0.000	0.992	0.008
K85.9 Acute pancreatitis, unspecified	0.000	0.992	0.008
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction	0.000	0.992	0.007
K80.4 Calculus of bile duct with cholecystitis	0.000	0.992	0.008
K82 Other diseases of gallbladder	0.000	0.992	0.008
K86.9 Disease of pancreas, unspecified	0.000	0.992	0.007
H04.1 Other disorders of lachrymal gland	0.007	0.993	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.007	0.993	0.000
K82.1 Hydrops of gallbladder	0.000	0.993	0.007
K83.9 Disease of biliary tract, unspecified	0.000	0.993	0.007
K83.5 Biliary cyst	0.000	0.993	0.007
K83.4 Spasm of sphincter of Oddi	0.000	0.993	0.007
K83.3 Fistula of bile duct	0.000	0.993	0.007
K83.2 Perforation of bile duct	0.000	0.993	0.007
K82.8 Other specified diseases of gallbladder	0.000	0.993	0.007
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.993	0.007
M54.59 Low back pain (Site unspecified)	0.007	0.993	0.000
K83.8 Other specified diseases of biliary tract	0.000	0.993	0.007
K85.8 Other acute pancreatitis	0.000	0.993	0.006
K85.3 Drug-induced acute pancreatitis	0.000	0.993	0.006
K85.0 Idiopathic acute pancreatitis	0.000	0.993	0.006
O34.1 Maternal care for tumour of corpus uteri	0.006	0.993	0.000
K85.1 Biliary acute pancreatitis	0.000	0.994	0.006
I31.9 Disease of pericardium, unspecified	0.000	0.994	0.006
K81.1 Chronic cholecystitis	0.000	0.994	0.006
Z87.1 Personal history of diseases of the digestive system	0.000	0.994	0.006
K87.1 Disorders of pancreas in diseases classified elsewhere	0.000	0.994	0.006
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere	0.000	0.994	0.006
O34.7 Maternal care for abnormality of vulva and perineum	0.006	0.994	0.000
O34.8 Maternal care for other abnormalities of pelvic organs	0.006	0.994	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.006	0.994	0.000
K82.3 Fistula of gallbladder	0.000	0.994	0.006
K82.0 Obstruction of gallbladder	0.000	0.994	0.006
K85.2 Alcohol-induced acute pancreatitis	0.000	0.994	0.005
K81.0 Acute cholecystitis	0.000	0.994	0.006
I51.7 Cardiomegaly	0.006	0.994	0.000
K81.9 Cholecystitis, unspecified	0.000	0.994	0.006
I51 Complications and ill-defined descriptions of heart disease	0.005	0.995	0.000
I51.8 Other ill-defined heart diseases	0.005	0.995	0.000
K80.8 Other cholelithiasis	0.001	0.995	0.005
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.005	0.995	0.000
O34.6 Maternal care for abnormality of vagina	0.005	0.995	0.000
O34.5 Maternal care for other abnormalities of gravid uterus	0.005	0.995	0.000
O34.3 Maternal care for cervical incompetence	0.005	0.995	0.000
O34.0 Maternal care for congenital malformation of uterus	0.005	0.995	0.000
C54 Malignant neoplasm of corpus uteri	0.000	0.995	0.005
K81.8 Other cholecystitis	0.000	0.995	0.005
H01 Other inflammation of eyelid	0.005	0.995	0.000
I51.6 Cardiovascular disease, unspecified	0.005	0.995	0.000
K86.2 Cyst of pancreas	0.000	0.995	0.005
H05 Disorders of orbit	0.005	0.995	0.000
C62.9 Testis, unspecified	0.005	0.995	0.000
H05.8 Other disorders of orbit	0.005	0.995	0.000
I51.9 Heart disease, unspecified	0.005	0.995	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.005	0.995	0.000
H93 Other disorders of ear, not elsewhere classified	0.005	0.995	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.005	0.995	0.000
H03 Disorders of eyelid in diseases classified elsewhere	0.005	0.995	0.000
H02.4 Ptosis of eyelid	0.005	0.995	0.000
O34.4 Maternal care for other abnormalities of cervix	0.005	0.995	0.000
K82.9 Disease of gallbladder, unspecified	0.000	0.995	0.005
H01.8 Other specified inflammation of eyelid	0.005	0.995	0.000
H01.1 Non-infectious dermatoses of eyelid	0.004	0.995	0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions	0.000	0.995	0.005
K82.2 Perforation of gallbladder	0.000	0.996	0.004
I51.4 Myocarditis, unspecified	0.004	0.996	0.000
I44.2 Atrioventricular block, complete	0.004	0.996	0.000
H93.8 Other specified disorders of ear	0.004	0.996	0.000
N18.3 Chronic kidney disease, stage 3	0.004	0.996	0.000
I51.5 Myocardial degeneration	0.004	0.996	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.004	0.996	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.004	0.996	0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.004	0.996	0.000
H65 Nonsuppurative otitis media	0.004	0.996	0.000
H06.2 Dysthyroid exophthalmos	0.004	0.996	0.000
C43.5 Malignant melanoma of trunk	0.000	0.996	0.004
I31 Other diseases of pericardium	0.001	0.996	0.004
H03.1 Involvement of eyelid in other infectious diseases classified elsewhere	0.004	0.996	0.000
O02.1 Missed abortion	0.000	0.996	0.004
H74 Other disorders of middle ear and mastoid	0.004	0.996	0.000
C54.9 Corpus uteri, unspecified	0.000	0.996	0.004
C54.8 Overlapping lesion of corpus uteri	0.000	0.996	0.004
C54.3 Fundus uteri	0.000	0.996	0.004
C54.2 Myometrium	0.000	0.996	0.004
C54.0 Isthmus uteri	0.000	0.996	0.004
H74.3 Other acquired abnormalities of ear ossicles	0.004	0.996	0.000
H01.9 Inflammation of eyelid, unspecified	0.004	0.996	0.000
H65.4 Other chronic nonsuppurative otitis media	0.004	0.996	0.000
H05.9 Disorder of orbit, unspecified	0.004	0.996	0.000
H05.5 Retained (old) foreign body following penetrating wound of orbit	0.004	0.996	0.000
H05.4 Enophthalmos	0.004	0.996	0.000
H05.3 Deformity of orbit	0.004	0.996	0.000
H05.1 Chronic inflammatory disorders of orbit	0.004	0.996	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.004	0.996	0.000
H05.2 Exophthalmic conditions	0.004	0.996	0.000
H06.3 Other disorders of orbit in diseases classified elsewhere	0.004	0.996	0.000
H06.1 Parasitic infestation of orbit in diseases classified elsewhere	0.004	0.996	0.000
H06.0 Disorders of lachrymal system in diseases classified elsewhere	0.004	0.996	0.000
H93.3 Disorders of acoustic nerve	0.004	0.996	0.000
H93.2 Other abnormal auditory perceptions	0.004	0.996	0.000
H93.0 Degenerative and vascular disorders of ear	0.004	0.996	0.000
H03.8 Involvement of eyelid in other diseases classified elsewhere	0.004	0.996	0.000
H03.0 Parasitic infestation of eyelid in diseases classified elsewhere	0.004	0.996	0.000
H01.0 Blepharitis	0.004	0.996	0.000
N17-N19 Renal failure	0.004	0.996	0.000
R79.0 Abnormal level of blood mineral	0.004	0.996	0.000
Z99.1 Dependence on respirator	0.004	0.996	0.000
F03 Unspecified dementia	0.000	0.996	0.004
H74.2 Discontinuity and dislocation of ear ossicles	0.004	0.996	0.000
H74.0 Tympanosclerosis	0.004	0.996	0.000
D12.3 Transverse colon	0.000	0.996	0.004
H93.9 Disorder of ear, unspecified	0.003	0.996	0.000
I31.3 Pericardial effusion (noninflammatory)	0.000	0.997	0.003
Z99.8 Dependence on other enabling machines and devices	0.003	0.997	0.000
K83.1 Obstruction of bile duct	0.000	0.997	0.003
H74.1 Adhesive middle ear disease	0.003	0.997	0.000
K57 Diverticular disease of intestine	0.000	0.997	0.003
H65-H75 Diseases of middle ear and mastoid	0.003	0.997	0.000
H05.0 Acute inflammation of orbit	0.003	0.997	0.000
H65.0 Acute serous otitis media	0.003	0.997	0.000
N18 Chronic renal failure	0.003	0.997	0.000
H65.1 Other acute nonsuppurative otitis media	0.003	0.997	0.000
I67.9 Cerebrovascular disease, unspecified	0.003	0.997	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.003	0.997	0.000
I31.8 Other specified diseases of pericardium	0.001	0.997	0.003
I31.2 Haemopericardium, not elsewhere classified	0.001	0.997	0.003
I31.1 Chronic constrictive pericarditis	0.001	0.997	0.003
I31.0 Chronic adhesive pericarditis	0.001	0.997	0.003
K82.4 Cholesterolosis of gallbladder	0.000	0.997	0.003
N18.8 Other chronic renal failure	0.003	0.997	0.000
J39.2 Other diseases of pharynx	0.003	0.997	0.000
F01.9 Vascular dementia, unspecified	0.000	0.997	0.003
H65.3 Chronic mucoid otitis media	0.003	0.997	0.000
E61.1 Iron deficiency	0.003	0.997	0.000
I51.0 Cardiac septal defect, acquired	0.003	0.997	0.000
H66 Suppurative and unspecified otitis media	0.003	0.997	0.000
H65.2 Chronic serous otitis media	0.003	0.997	0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.003	0.997	0.000
G61.0 Guillain-Barre syndrome	0.000	0.997	0.003
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.000	0.997	0.003
Y83.8 Other surgical procedures	0.000	0.997	0.003
H66.3 Other chronic suppurative otitis media	0.003	0.997	0.000
N18.5 Chronic kidney disease, stage 5	0.003	0.997	0.000
K22.4 Dyskinesia of oesophagus	0.000	0.997	0.003
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.003	0.997	0.000
H74.4 Polyp of middle ear	0.003	0.997	0.000
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess	0.000	0.997	0.003
H66.2 Chronic atticoantral suppurative otitis media	0.003	0.997	0.000
Z99.2 Dependence on renal dialysis	0.003	0.997	0.000
J33.9 Nasal polyp, unspecified	0.003	0.997	0.000
N13.8 Other obstructive and reflux uropathy	0.000	0.997	0.003
I34.1 Mitral (valve) prolapse	0.003	0.997	0.000
K57.5 Diverticular disease of both small and large intestine without perforation or abscess	0.000	0.997	0.003
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.003	0.997	0.000
H68 Eustachian salpingitis and obstruction	0.003	0.997	0.000
H67 Otitis media in diseases classified elsewhere	0.003	0.997	0.000
K07.6 Temporomandibular joint disorders	0.000	0.997	0.003
N18.1 Chronic kidney disease, stage 1	0.003	0.997	0.000
H02 Other disorders of eyelid	0.003	0.997	0.000
F01 Vascular dementia	0.000	0.997	0.003
H69 Other disorders of Eustachian tube	0.003	0.997	0.000
F06.7 Mild cognitive disorder	0.000	0.997	0.003
H73 Other disorders of tympanic membrane	0.003	0.997	0.000
H49.0 Third [oculomotor] nerve palsy	0.000	0.997	0.003
E55.9 Vitamin D deficiency, unspecified	0.003	0.997	0.000
Y40.0 Penicillins	0.003	0.997	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.002	0.997	0.000
K57.0 Diverticular disease of small intestine with perforation and abscess	0.000	0.997	0.002
K57.4 Diverticular disease of both small and large intestine with perforation and abscess	0.000	0.997	0.002
H66.4 Suppurative otitis media, unspecified	0.002	0.998	0.000
H66.0 Acute suppurative otitis media	0.002	0.998	0.000
Y54.5 Other diuretics	0.002	0.998	0.000
C56 Malignant neoplasm of ovary	0.000	0.998	0.002
C62 Malignant neoplasm of testis	0.002	0.998	0.000
H70 Mastoiditis and related conditions	0.002	0.998	0.000
K57.2 Diverticular disease of large intestine with perforation and abscess	0.000	0.998	0.002
Z99.9 Dependence on unspecified enabling machine and device	0.002	0.998	0.000
Z99.4 Dependence on artificial heart	0.002	0.998	0.000
Z99.0 Dependence on aspirator	0.002	0.998	0.000
N18.4 Chronic kidney disease, stage 4	0.002	0.998	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.000	0.998	0.002
I30-I52 Other forms of heart disease	0.002	0.998	0.000
H02.5 Other disorders affecting eyelid function	0.002	0.998	0.000
H00 Hordeolum and chalazion	0.002	0.998	0.000
H72 Perforation of tympanic membrane	0.002	0.998	0.000
H69.9 Eustachian tube disorder, unspecified	0.002	0.998	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.000	0.998	0.002
R41.3 Other amnesia	0.000	0.998	0.002
F00-F09 Organic, including symptomatic, mental disorders	0.000	0.998	0.002
H73.9 Disorder of tympanic membrane, unspecified	0.002	0.998	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.002	0.998	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.002	0.998	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.002	0.998	0.000
H68.1 Obstruction of Eustachian tube	0.002	0.998	0.000
H68.0 Eustachian salpingitis	0.002	0.998	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.002	0.998	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
F01.8 Other vascular dementia	0.000	0.998	0.002
F01.3 Mixed cortical and subcortical vascular dementia	0.000	0.998	0.002
F01.2 Subcortical vascular dementia	0.000	0.998	0.002
F01.1 Multi-infarct dementia	0.000	0.998	0.002
F01.0 Vascular dementia of acute onset	0.000	0.998	0.002
H02.7 Other degenerative disorders of eyelid and periocular area	0.002	0.998	0.000
H69.0 Patulous Eustachian tube	0.002	0.998	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.002	0.998	0.000
H02.2 Lagophthalmos	0.002	0.998	0.000
N13.4 Hydroureter	0.000	0.998	0.002
N18.9 Chronic renal failure, unspecified	0.002	0.998	0.000
H02.6 Xanthelasma of eyelid	0.002	0.998	0.000
H49.2 Sixth [abducent] nerve palsy	0.000	0.998	0.002
H73.1 Chronic myringitis	0.002	0.998	0.000
H73.0 Acute myringitis	0.002	0.998	0.000
E61 Deficiency of other nutrient elements	0.002	0.998	0.000
Y40 Systemic antibiotics	0.002	0.998	0.000
K13.0 Diseases of lips	0.002	0.998	0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess	0.000	0.998	0.002
H49 Paralytic strabismus	0.000	0.998	0.002
I34 Nonrheumatic mitral valve disorders	0.002	0.998	0.000
H66.9 Otitis media, unspecified	0.002	0.998	0.000
D37.5 Rectum	0.000	0.998	0.002
O86.0 Infection of obstetric surgical wound	0.002	0.998	0.000
Y54.7 Agents affecting calcification	0.002	0.998	0.000
C69.3 Choroid	0.002	0.998	0.000
I42.0 Dilated cardiomyopathy	0.002	0.998	0.000
C62.1 Descended testis	0.002	0.998	0.000
C62.0 Undescended testis	0.002	0.998	0.000
H49.1 Fourth [trochlear] nerve palsy	0.000	0.998	0.002
Z87.0 Personal history of diseases of the respiratory system	0.002	0.998	0.000
N13 Obstructive and reflux uropathy	0.000	0.998	0.002
H70.8 Other mastoiditis and related conditions	0.002	0.998	0.000
H70.2 Petrositis	0.002	0.998	0.000
H70.1 Chronic mastoiditis	0.002	0.998	0.000
H70.0 Acute mastoiditis	0.002	0.998	0.000
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease	0.000	0.998	0.002
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease	0.000	0.998	0.002
F06.6 Organic emotionally labile [asthenic] disorder	0.000	0.998	0.002
F06.5 Organic dissociative disorder	0.000	0.998	0.002
F06.4 Organic anxiety disorder	0.000	0.998	0.002
F06.3 Organic mood [affective] disorders	0.000	0.998	0.002
F06.2 Organic delusional [schizophrenia-like] disorder	0.000	0.998	0.002
F06.1 Organic catatonic disorder	0.000	0.998	0.002
F06.0 Organic hallucinosis	0.000	0.998	0.002
Z99.3 Dependence on wheelchair	0.002	0.998	0.000
I52 Other heart disorders in diseases classified elsewhere	0.002	0.998	0.000
I48 Atrial fibrillation and flutter	0.002	0.998	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.002	0.998	0.000
I41 Myocarditis in diseases classified elsewhere	0.002	0.998	0.000
I40 Acute myocarditis	0.002	0.998	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.002	0.998	0.000
I32 Pericarditis in diseases classified elsewhere	0.002	0.998	0.000
Y40.9 Systemic antibiotic, unspecified	0.002	0.998	0.000
I67 Other cerebrovascular diseases	0.002	0.998	0.000
H69.8 Other specified disorders of Eustachian tube	0.002	0.998	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.000	0.998	0.002
C51-C58 Malignant neoplasms of female genital organs	0.000	0.998	0.002
H72.1 Attic perforation of tympanic membrane	0.002	0.998	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.002	0.998	0.000
N17 Acute renal failure	0.002	0.998	0.000
H72.8 Other perforations of tympanic membrane	0.002	0.998	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.002	0.998	0.000
H73.8 Other specified disorders of tympanic membrane	0.002	0.998	0.000
E55 Vitamin D deficiency	0.002	0.998	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.002	0.998	0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.000	0.998	0.002
F09 Unspecified organic or symptomatic mental disorder	0.000	0.998	0.002
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.000	0.998	0.002
N13.9 Obstructive and reflux uropathy, unspecified	0.000	0.998	0.002
F02 Dementia in other diseases classified elsewhere	0.000	0.998	0.002
Y41 Other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
H72.2 Other marginal perforations of tympanic membrane	0.002	0.998	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.002	0.998	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.002	0.998	0.000
Y54.9 Mineral salts, not elsewhere classified	0.002	0.998	0.000
Y54.8 Agents affecting uric acid metabolism	0.002	0.998	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.002	0.998	0.000
Y54.4 Loop [high-ceiling] diuretics	0.002	0.998	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.002	0.998	0.000
Y54.0 Mineralocorticoids	0.002	0.998	0.000
J39 Other diseases of upper respiratory tract	0.002	0.998	0.000
J33.0 Polyp of nasal cavity	0.002	0.998	0.000
I42 Cardiomyopathy	0.002	0.998	0.000
E61.9 Deficiency of nutrient element, unspecified	0.002	0.998	0.000
E61.8 Deficiency of other specified nutrient elements	0.002	0.998	0.000
E61.7 Deficiency of multiple nutrient elements	0.002	0.998	0.000
E61.6 Vanadium deficiency	0.002	0.998	0.000
E61.5 Molybdenum deficiency	0.002	0.998	0.000
E61.4 Chromium deficiency	0.002	0.998	0.000
E61.3 Manganese deficiency	0.002	0.998	0.000
E61.2 Magnesium deficiency	0.002	0.998	0.000
E61.0 Copper deficiency	0.002	0.998	0.000
H72.0 Central perforation of tympanic membrane	0.002	0.998	0.000
I89.0 Lymphoedema, not elsewhere classified	0.000	0.998	0.002
Y40.7 Antifungal antibiotics, systemically used	0.002	0.998	0.000
Y40.6 Rifamycins	0.002	0.998	0.000
Y40.5 Aminoglycosides	0.002	0.998	0.000
Y40.4 Tetracyclines	0.002	0.998	0.000
Y40.2 Chloramphenicol group	0.002	0.998	0.000
H49.9 Paralytic strabismus, unspecified	0.000	0.998	0.002
H49.8 Other paralytic strabismus	0.000	0.998	0.002
H49.4 Progressive external ophthalmoplegia	0.000	0.998	0.002
H49.3 Total (external) ophthalmoplegia	0.000	0.998	0.002
I34.2 Nonrheumatic mitral (valve) stenosis	0.002	0.998	0.000
N17.8 Other acute renal failure	0.002	0.998	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.002	0.998	0.000
I67.8 Other specified cerebrovascular diseases	0.002	0.998	0.000
J39.0 Retropharyngeal and parapharyngeal abscess	0.002	0.998	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.002	0.998	0.000
H70.9 Mastoiditis, unspecified	0.001	0.998	0.000
Y41.5 Antiviral drugs	0.002	0.998	0.000
I33 Acute and subacute endocarditis	0.002	0.998	0.000
I30 Acute pericarditis	0.002	0.998	0.000
I37 Pulmonary valve disorders	0.002	0.998	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.000	0.998	0.002
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.002	0.998	0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue	0.002	0.998	0.000
C69 Malignant neoplasm of eye and adnexa	0.002	0.998	0.000
N85 Other noninflammatory disorders of uterus, except cervix	0.000	0.998	0.002
I32.8 Pericarditis in other diseases classified elsewhere	0.001	0.998	0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.001	0.998	0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.001	0.998	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.002	0.998	0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.001	0.998	0.000
I39.4 Multiple valve disorders in diseases classified elsewhere	0.001	0.998	0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.001	0.998	0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.001	0.998	0.000
I39.1 Aortic valve disorders in diseases classified elsewhere	0.001	0.998	0.000
I39.0 Mitral valve disorders in diseases classified elsewhere	0.001	0.998	0.000
I40.9 Acute myocarditis, unspecified	0.001	0.998	0.000
I40.8 Other acute myocarditis	0.001	0.998	0.000
I40.1 Isolated myocarditis	0.001	0.998	0.000
I40.0 Infective myocarditis	0.001	0.998	0.000
I41.8 Myocarditis in other diseases classified elsewhere	0.001	0.998	0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.001	0.998	0.000
I41.1 Myocarditis in viral diseases classified elsewhere	0.001	0.998	0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.001	0.998	0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.001	0.998	0.000
I43.2 Cardiomyopathy in nutritional diseases	0.001	0.998	0.000
I43.1 Cardiomyopathy in metabolic diseases	0.001	0.998	0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.001	0.998	0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.001	0.998	0.000
I48.4 Atypical atrial flutter	0.001	0.998	0.000
I48.3 Typical atrial flutter	0.001	0.998	0.000
I48.2 Chronic atrial fibrillation	0.001	0.998	0.000
I48.1 Persistent atrial fibrillation	0.001	0.998	0.000
I48.0 Paroxysmal atrial fibrillation	0.001	0.998	0.000
I52.8 Other heart disorders in other diseases classified elsewhere	0.001	0.998	0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.001	0.998	0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.001	0.998	0.000
N13.6 Pyonephrosis	0.000	0.998	0.002
I44 Atrioventricular and left bundle-branch block	0.002	0.998	0.000
I36 Nonrheumatic tricuspid valve disorders	0.001	0.998	0.000
O02 Other abnormal products of conception	0.000	0.998	0.002
H72.9 Perforation of tympanic membrane, unspecified	0.002	0.998	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.002	0.998	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.002	0.998	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.002	0.998	0.000
I67.5 Moyamoya disease	0.002	0.998	0.000
I67.4 Hypertensive encephalopathy	0.002	0.998	0.000
I67.3 Progressive vascular leukoencephalopathy	0.002	0.998	0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.000	0.998	0.002
C58 Malignant neoplasm of placenta	0.000	0.998	0.002
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
C71.9 Brain, unspecified	0.002	0.998	0.000
J44.8 Other specified chronic obstructive pulmonary disease	0.000	0.998	0.002
N17.2 Acute renal failure with medullary necrosis	0.002	0.998	0.000
N17.1 Acute renal failure with acute cortical necrosis	0.002	0.998	0.000
N85.9 Noninflammatory disorder of uterus, unspecified	0.000	0.998	0.002
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.002	0.998	0.000
Y48 Anaesthetics and therapeutic gases	0.002	0.998	0.000
S02.10 Fracture of base of skull (closed)	0.000	0.998	0.002
C69.0 Conjunctiva	0.002	0.998	0.000
I83.0 Varicose veins of lower extremities with ulcer	0.002	0.998	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.000	0.998	0.002
N18.2 Chronic kidney disease, stage 2	0.001	0.998	0.000
Y54.3 Benzothiadiazine derivatives	0.002	0.998	0.000
E55.0 Rickets, active	0.001	0.998	0.000
F02.3 Dementia in Parkinson's disease	0.000	0.998	0.001
F07.9 Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction	0.000	0.998	0.001
F07.8 Other organic personality and behavioural disorders due to brain disease, damage and dysfunction	0.000	0.998	0.001
F07.2 Postconcussional syndrome	0.000	0.998	0.001
F07.1 Postencephalitic syndrome	0.000	0.998	0.001
F07.0 Organic personality disorder	0.000	0.998	0.001
I67.2 Cerebral atherosclerosis	0.002	0.998	0.000
Y40.3 Macrolides	0.001	0.998	0.000
C52 Malignant neoplasm of vagina	0.000	0.998	0.001
C18.7 Sigmoid colon	0.000	0.998	0.002
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.001	0.998	0.000
Y41.4 Anthelminthics	0.001	0.998	0.000
Y41.3 Other antiprotozoal drugs	0.001	0.998	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.001	0.998	0.000
Y41.1 Antimycobacterial drugs	0.001	0.998	0.000
Y48.4 Anaesthetic, unspecified	0.001	0.998	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.001	0.998	0.000
C57 Malignant neoplasm of other and unspecified female genital organs	0.000	0.998	0.001
K07 Dentofacial anomalies [including malocclusion]	0.000	0.998	0.002
O86 Other puerperal infections	0.002	0.998	0.000
F02.4 Dementia in human immunodeficiency virus [HIV] disease	0.000	0.998	0.001
F02.2 Dementia in Huntington's disease	0.000	0.998	0.001
F02.1 Dementia in Creutzfeldt-Jakob disease	0.000	0.998	0.001
F02.0 Dementia in Pick's disease	0.000	0.998	0.001
N17.0 Acute renal failure with tubular necrosis	0.001	0.998	0.000
Y41.0 Sulphonamides	0.001	0.998	0.000
Y53.4 Other laxatives	0.001	0.998	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.001	0.998	0.000
C18.9 Colon, unspecified	0.000	0.998	0.002
I42.7 Cardiomyopathy due to drugs and other external agents	0.001	0.998	0.000
I42.5 Other restrictive cardiomyopathy	0.001	0.998	0.000
I42.4 Endocardial fibroelastosis	0.001	0.998	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.001	0.998	0.000
J39.9 Disease of upper respiratory tract, unspecified	0.001	0.998	0.000
J39.3 Upper respiratory tract hypersensitivity reaction, site unspecified	0.001	0.998	0.000
J39.1 Other abscess of pharynx	0.001	0.998	0.000
W44.0 Home	0.002	0.998	0.000
C18.2 Ascending colon	0.000	0.998	0.002
I42.9 Cardiomyopathy, unspecified	0.002	0.998	0.000
H02.1 Ectropion of eyelid	0.002	0.998	0.000
K07.3 Anomalies of tooth position	0.000	0.998	0.002
N13.7 Vesicoureteral-reflux-associated uropathy	0.000	0.998	0.001
J33 Nasal polyp	0.002	0.998	0.000
Y59 Other and unspecified vaccines and biological substances	0.001	0.998	0.000
Y58 Bacterial vaccines	0.001	0.998	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.001	0.998	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.001	0.998	0.000
Y44 Agents primarily affecting blood constituents	0.001	0.998	0.000
I30.8 Other forms of acute pericarditis	0.001	0.998	0.000
I30.0 Acute nonspecific idiopathic pericarditis	0.001	0.998	0.000
I33.9 Acute endocarditis, unspecified	0.001	0.998	0.000
I42.6 Alcoholic cardiomyopathy	0.001	0.998	0.000
K12.3 Oral mucositis (ulcerative)	0.000	0.998	0.002
K29.5 Chronic gastritis, unspecified	0.000	0.998	0.002
O86.2 Urinary tract infection following delivery	0.001	0.998	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.001	0.998	0.000
Y45.4 Antirheumatics	0.001	0.998	0.000
C71 Malignant neoplasm of brain	0.002	0.998	0.000
C69.9 Eye, unspecified	0.001	0.998	0.000
F02.8 Dementia in other specified diseases classified elsewhere	0.000	0.998	0.001
I37.9 Pulmonary valve disorder, unspecified	0.001	0.998	0.000
I37.8 Other pulmonary valve disorders	0.001	0.998	0.000
I37.2 Pulmonary valve stenosis with insufficiency	0.001	0.998	0.000
I37.0 Pulmonary valve stenosis	0.001	0.998	0.000
N28.9 Disorder of kidney and ureter, unspecified	0.002	0.998	0.000
Y45.8 Other analgesics and antipyretics	0.001	0.998	0.000
Y45.5 4-Aminophenol derivatives	0.001	0.998	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.001	0.998	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.001	0.998	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations