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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs13126505
log Bayes Factor = 11.7035
Chromosome 4   position 102,865,304  (GRCh37) Explore rs13126505 on Ensembl!
Variant rs13126505 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
M70-M79 Other soft tissue disorders
1.000 0.000 0.000
M75 Shoulder lesions
0.999 0.001 0.000
M20 Acquired deformities of fingers and toes
0.998 0.002 0.000
M50-M54 Other dorsopathies
0.996 0.004 0.000
I10 Essential (primary) hypertension
0.000 0.005 0.995
M25 Other joint disorders, not elsewhere classified
0.994 0.006 0.000
M75.1 Rotator cuff syndrome
0.992 0.008 0.000
M54 Dorsalgia
0.988 0.012 0.000
M54.5 Low back pain
0.984 0.016 0.000
M20.3 Other deformity of hallux (acquired)
0.983 0.017 0.000
M54.56 Low back pain (Lumbar region)
0.982 0.018 0.000
M77 Other enthesopathies
0.980 0.020 0.000
M45-M49 Spondylopathies
0.975 0.025 0.000
M20.4 Other hammer toe(s) (acquired)
0.971 0.029 0.000
M75.5 Bursitis of shoulder
0.969 0.031 0.000
I10-I15 Hypertensive diseases
0.000 0.034 0.966
M05-M14 Inflammatory polyarthropathies
0.965 0.035 0.000
M75.0 Adhesive capsulitis of shoulder
0.960 0.040 0.000
M13 Other arthritis
0.957 0.043 0.000
M22 Disorders of patella
0.956 0.044 0.000
M15-M19 Arthrosis
0.953 0.047 0.000
M13.9 Arthritis, unspecified
0.952 0.048 0.000
M25.4 Effusion of joint
0.950 0.050 0.000
I12 Hypertensive renal disease
0.000 0.055 0.945
M13.99 Arthritis, unspecified (Site unspecified)
0.945 0.055 0.000
M77.1 Lateral epicondylitis
0.945 0.055 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.926 0.074 0.000
M80-M85 Disorders of bone density and structure
0.926 0.074 0.000
M45 Ankylosing spondylitis
0.924 0.076 0.000
M50 Cervical disk disorders
0.924 0.076 0.000
M77.12 Lateral epicondylitis (Upper arm)
0.920 0.080 0.000
M86-M90 Other osteopathies
0.919 0.081 0.000
I12.0 Hypertensive renal disease with renal failure
0.000 0.082 0.918
M20.1 Hallux valgus (acquired)
0.918 0.082 0.000
M25.7 Osteophyte
0.918 0.082 0.000
M25.8 Other specified joint disorders
0.917 0.083 0.000
M91-M94 Chondropathies
0.886 0.114 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.867 0.133 0.000
M25.84 Other specified joint disorders (Hand)
0.861 0.139 0.000
M25.76 Osteophyte (Lower leg)
0.855 0.145 0.000
M77.9 Enthesopathy, unspecified
0.848 0.152 0.000
M25.46 Effusion of joint (Lower leg)
0.844 0.156 0.000
M40-M43 Deforming dorsopathies
0.844 0.156 0.000
M80 Osteoporosis with pathological fracture
0.837 0.163 0.000
M25.45 Effusion of joint (Pelvic region and thigh)
0.834 0.166 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.834 0.166 0.000
M50.3 Other cervical disk degeneration
0.834 0.166 0.000
M87 Osteonecrosis
0.832 0.168 0.000
M15 Polyarthrosis
0.830 0.170 0.000
M54.2 Cervicalgia
0.827 0.173 0.000
M75.3 Calcific tendinitis of shoulder
0.816 0.184 0.000
M50.2 Other cervical disk displacement
0.814 0.186 0.000
M19 Other arthrosis
0.813 0.187 0.000
M49 Spondylopathies in diseases classified elsewhere
0.808 0.192 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.806 0.194 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.806 0.194 0.000
I12.9 Hypertensive renal disease without renal failure
0.000 0.199 0.801
I15 Secondary hypertension
0.000 0.201 0.799
M17 Gonarthrosis [arthrosis of knee]
0.792 0.208 0.000
M22.3 Other derangements of patella
0.789 0.211 0.000
M22.0 Recurrent dislocation of patella
0.787 0.213 0.000
M46 Other inflammatory spondylopathies
0.786 0.213 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.781 0.219 0.000
M87.9 Osteonecrosis, unspecified
0.781 0.219 0.000
M48 Other spondylopathies
0.777 0.222 0.000
M53 Other dorsopathies, not elsewhere classified
0.772 0.228 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.767 0.233 0.000
M17.0 Primary gonarthrosis, bilateral
0.767 0.233 0.000
M25.9 Joint disorder, unspecified
0.766 0.234 0.000
M22.2 Patellofemoral disorders
0.766 0.234 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.765 0.235 0.000
M81 Osteoporosis without pathological fracture
0.765 0.235 0.000
M25.0 Haemarthrosis
0.765 0.235 0.000
M86 Osteomyelitis
0.764 0.236 0.000
M16 Coxarthrosis [arthrosis of hip]
0.763 0.237 0.000
M22.9 Disorder of patella, unspecified
0.761 0.239 0.000
M94 Other disorders of cartilage
0.761 0.239 0.000
M54.50 Low back pain (Multiple sites in spine)
0.754 0.246 0.000
M22.8 Other disorders of patella
0.747 0.253 0.000
M22.4 Chondromalacia patellae
0.746 0.253 0.000
I11 Hypertensive heart disease
0.000 0.255 0.745
M07 Psoriatic and enteropathic arthropathies
0.744 0.256 0.000
M25.40 Effusion of joint (Multiple sites)
0.743 0.257 0.000
M54.55 Low back pain (Thoracolumbar region)
0.742 0.258 0.000
M54.8 Other dorsalgia
0.738 0.262 0.000
M77.4 Metatarsalgia
0.737 0.262 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.734 0.266 0.000
M16.7 Other secondary coxarthrosis
0.732 0.268 0.000
M77.91 Enthesopathy, unspecified (Shoulder region)
0.732 0.268 0.000
M79.5 Residual foreign body in soft tissue
0.730 0.270 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.729 0.271 0.000
M25.87 Other specified joint disorders (Ankle and foot)
0.727 0.273 0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)
0.726 0.274 0.000
M50.9 Cervical disk disorder, unspecified
0.725 0.275 0.000
M41 Scoliosis
0.724 0.276 0.000
M25.42 Effusion of joint (Upper arm)
0.723 0.277 0.000
M06 Other rheumatoid arthritis
0.723 0.277 0.000
M93 Other osteochondropathies
0.722 0.278 0.000
M20.0 Deformity of finger(s)
0.718 0.282 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.718 0.282 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
M33 Dermatopolymyositis
0.717 0.283 0.000
M32 Systemic lupus erythematosus
0.717 0.283 0.000
M30 Polyarteritis nodosa and related conditions
0.717 0.283 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.717 0.283 0.000
M75.8 Other shoulder lesions
0.717 0.283 0.000
M19.9 Arthrosis, unspecified
0.716 0.284 0.000
M89 Other disorders of bone
0.716 0.284 0.000
M25.3 Other instability of joint
0.714 0.286 0.000
M25.2 Flail joint
0.712 0.287 0.000
M25.1 Fistula of joint
0.712 0.287 0.000
M76 Enthesopathies of lower limb, excluding foot
0.709 0.291 0.000
M54.0 Panniculitis affecting regions of neck and back
0.708 0.292 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.706 0.294 0.000
M54.54 Low back pain-Thoracic
0.705 0.294 0.000
M54.53 Low back pain-Cervicothoracic
0.705 0.294 0.000
M54.52 Low back pain-Cervical
0.705 0.294 0.000
M54.51 Low back pain-Occipit-atl-axl
0.705 0.294 0.000
M79.54 Residual foreign body in soft tissue (Hand)
0.705 0.295 0.000
M77.8 Other enthesopathies, not elsewhere classified
0.702 0.298 0.000
M77.5 Other enthesopathy of foot
0.702 0.298 0.000
M77.3 Calcaneal spur
0.702 0.298 0.000
M77.2 Periarthritis of wrist
0.702 0.298 0.000
M77.0 Medial epicondylitis
0.702 0.298 0.000
M85 Other disorders of bone density and structure
0.695 0.305 0.000
I13 Hypertensive heart and renal disease
0.000 0.307 0.693
M12 Other specific arthropathies
0.692 0.308 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.692 0.308 0.000
M08 Juvenile arthritis
0.692 0.308 0.000
M65-M68 Disorders of synovium and tendon
0.689 0.311 0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)
0.688 0.312 0.000
M49.5 Collapsed vertebra in diseases classified elsewhere
0.687 0.313 0.000
M23 Internal derangement of knee
0.687 0.313 0.000
M40 Kyphosis and lordosis
0.686 0.314 0.000
M54.29 Cervicalgia-Site unspe
0.686 0.314 0.000
M13.8 Other specified arthritis
0.686 0.314 0.000
M13.1 Monoarthritis, not elsewhere classified
0.686 0.314 0.000
M22.1 Recurrent subluxation of patella
0.685 0.315 0.000
M15.1 Heberden's nodes (with arthropathy)
0.684 0.316 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.683 0.317 0.000
M54.9 Dorsalgia, unspecified
0.681 0.319 0.000
M25.49 Effusion of joint (Site unspecified)
0.681 0.319 0.000
M25.48 Effusion of joint (Other)
0.681 0.319 0.000
M25.44 Effusion of joint (Hand)
0.681 0.319 0.000
M25.43 Effusion of joint (Forearm)
0.681 0.319 0.000
M25.41 Effusion of joint (Shoulder region)
0.681 0.319 0.000
I15.1 Hypertension secondary to other renal disorders
0.000 0.320 0.680
M25.71 Osteophyte (Shoulder region)
0.678 0.322 0.000
M48.0 Spinal stenosis
0.677 0.323 0.000
M77.19 Lateral epicondylitis (Site unspecified)
0.677 0.323 0.000
M77.18 Lateral epicondylitis-Other
0.677 0.323 0.000
M77.17 Lateral epicondylitis-Ankle/Foot
0.677 0.323 0.000
M77.16 Lateral epicondylitis (Lower leg)
0.677 0.323 0.000
M77.15 Lateral epicondylitis (Pelvic region and thigh)
0.677 0.323 0.000
M77.14 Lateral epicondylitis-Hand
0.677 0.323 0.000
M77.13 Lateral epicondylitis-Forearm
0.677 0.323 0.000
M77.11 Lateral epicondylitis-Shldr region
0.677 0.323 0.000
M77.10 Lateral epicondylitis (Multiple sites)
0.677 0.323 0.000
M13.93 Arthritis, unspecified (Forearm)
0.677 0.323 0.000
M54.6 Pain in thoracic spine
0.677 0.323 0.000
M25.5 Pain in joint
0.672 0.328 0.000
M75.9 Shoulder lesion, unspecified
0.672 0.328 0.000
M15.8 Other polyarthrosis
0.666 0.334 0.000
M00-M03 Infectious arthropathies
0.665 0.335 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.665 0.335 0.000
M83 Adult osteomalacia
0.664 0.336 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.664 0.336 0.000
M54.4 Lumbago with sciatica
0.663 0.337 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.663 0.337 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.663 0.337 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.663 0.337 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.663 0.337 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.663 0.337 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.663 0.337 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.663 0.337 0.000
M50.8 Other cervical disk disorders
0.662 0.337 0.000
M87.96 Osteonecrosis, unspecified (Lower leg)
0.662 0.338 0.000
M81.9 Osteoporosis, unspecified
0.660 0.340 0.000
M25.47 Effusion of joint (Ankle and foot)
0.660 0.340 0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)
0.659 0.341 0.000
M25.79 Osteophyte (Site unspecified)
0.658 0.342 0.000
M25.73 Osteophyte (Forearm)
0.658 0.342 0.000
M25.70 Osteophyte (Multiple sites)
0.658 0.342 0.000
M82 Osteoporosis in diseases classified elsewhere
0.658 0.342 0.000
M25.89 Other specified joint disorders (Site unspecified)
0.657 0.342 0.000
M25.88 Other specified joint disorders (Other)
0.657 0.342 0.000
M25.83 Other specified joint disorders (Forearm)
0.657 0.342 0.000
M25.82 Other specified joint disorders (Upper arm)
0.657 0.342 0.000
M25.80 Other specified joint disorders (Multiple sites)
0.657 0.342 0.000
M25.78 Osteophyte (Other)
0.657 0.343 0.000
M25.72 Osteophyte (Upper arm)
0.656 0.344 0.000
M47 Spondylosis
0.655 0.345 0.000
M77.97 Enthesopathy, unspecified (Ankle and foot)
0.653 0.347 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.653 0.347 0.000
M94.8 Other specified disorders of cartilage
0.652 0.348 0.000
M19.0 Primary arthrosis of other joints
0.649 0.351 0.000
M60-M63 Disorders of muscles
0.648 0.352 0.000
M90 Osteopathies in diseases classified elsewhere
0.646 0.354 0.000
M14 Arthropathies in other diseases classified elsewhere
0.645 0.355 0.000
M79.1 Myalgia
0.645 0.355 0.000
M06.0 Seronegative rheumatoid arthritis
0.644 0.356 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.643 0.357 0.000
M84 Disorders of continuity of bone
0.638 0.362 0.000
M41.9 Scoliosis, unspecified
0.637 0.363 0.000
M25.81 Other specified joint disorders (Shoulder region)
0.636 0.363 0.000
M25.77 Osteophyte (Ankle and foot)
0.635 0.365 0.000
M92 Other juvenile osteochondrosis
0.635 0.365 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.635 0.365 0.000
M54.22 Cervicalgia (Cervical region)
0.635 0.365 0.000
M13.0 Polyarthritis, unspecified
0.633 0.367 0.000
M54.1 Radiculopathy
0.632 0.368 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.631 0.369 0.000
M21 Other acquired deformities of limbs
0.631 0.369 0.000
M15.2 Bouchard's nodes (with arthropathy)
0.626 0.374 0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)
0.625 0.375 0.000
M48.02 Spinal stenosis (Cervical region)
0.621 0.378 0.000
M71 Other bursopathies
0.621 0.379 0.000
M87.91 Osteonecrosis, unspecified (Shoulder region)
0.620 0.379 0.000
M11 Other crystal arthropathies
0.614 0.385 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.615 0.385 0.000
M86.8 Other osteomyelitis
0.612 0.387 0.000
M25.56 Pain in joint (Lower leg)
0.613 0.387 0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified
0.611 0.388 0.000
M17.3 Other posttraumatic gonarthrosis
0.610 0.390 0.000
M18 Arthrosis of first carpometacarpal joint
0.610 0.390 0.000
M77.99 Enthesopathy, unspecified (Site unspecified)
0.608 0.392 0.000
M77.98 Enthesopathy, unspecified (Other)
0.608 0.392 0.000
M77.96 Enthesopathy, unspecified (Lower leg)
0.608 0.392 0.000
M77.95 Enthesopathy, unspecified (Pelvic region and thigh)
0.608 0.392 0.000
M77.94 Enthesopathy, unspecified (Hand)
0.608 0.392 0.000
M77.93 Enthesopathy, unspecified (Forearm)
0.608 0.392 0.000
M77.92 Enthesopathy, unspecified (Upper arm)
0.608 0.392 0.000
M77.90 Enthesopathy, unspecified (Multiple sites)
0.608 0.392 0.000
M50.1 Cervical disk disorder with radiculopathy
0.607 0.393 0.000
M93.9 Osteochondropathy, unspecified
0.605 0.395 0.000
M42 Spinal osteochondrosis
0.605 0.395 0.000
M23.8 Other internal derangements of knee
0.603 0.396 0.000
M25.96 Joint disorder, unspecified (Lower leg)
0.603 0.397 0.000
M25.06 Haemarthrosis (Lower leg)
0.601 0.399 0.000
M49.54 Collapsed vertebra in diseases classified elsewhere (Thoracic region)
0.601 0.399 0.000
M80.8 Other osteoporosis with pathological fracture
0.600 0.400 0.000
M80.5 Idiopathic osteoporosis with pathological fracture
0.600 0.400 0.000
M80.4 Drug-induced osteoporosis with pathological fracture
0.600 0.400 0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture
0.600 0.400 0.000
M80.2 Osteoporosis of disuse with pathological fracture
0.600 0.400 0.000
M25.74 Osteophyte (Hand)
0.600 0.400 0.000
M87.8 Other osteonecrosis
0.596 0.404 0.000
M87.3 Other secondary osteonecrosis
0.596 0.404 0.000
M87.1 Osteonecrosis due to drugs
0.596 0.404 0.000
M87.0 Idiopathic aseptic necrosis of bone
0.596 0.404 0.000
M15.9 Polyarthrosis, unspecified
0.595 0.405 0.000
M15.0 Primary generalised (osteo)arthrosis
0.595 0.405 0.000
M15.4 Erosive (osteo)arthrosis
0.595 0.405 0.000
M15.3 Secondary multiple arthrosis
0.595 0.405 0.000
M31 Other necrotising vasculopathies
0.595 0.405 0.000
M86.9 Osteomyelitis, unspecified
0.594 0.406 0.000
M54.28 Cervicalgia-Sacral/sacrococ
0.593 0.407 0.000
M54.27 Cervicalgia-Lumbosacral
0.593 0.407 0.000
M54.26 Cervicalgia-Lumbar
0.593 0.407 0.000
M54.25 Cervicalgia-Thoracolumbar
0.593 0.407 0.000
M54.24 Cervicalgia-Thoracic
0.593 0.407 0.000
M54.23 Cervicalgia (Cervicothoracic region)
0.593 0.407 0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)
0.593 0.407 0.000
M54.20 Cervicalgia-Mult site
0.593 0.407 0.000
M25.86 Other specified joint disorders (Lower leg)
0.593 0.407 0.000
M34 Systemic sclerosis
0.588 0.412 0.000
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.414 0.586
M07.3 Other psoriatic arthropathies
0.586 0.414 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.584 0.416 0.000
M19.8 Other specified arthrosis
0.583 0.417 0.000
M19.2 Other secondary arthrosis
0.583 0.417 0.000
M94.2 Chondromalacia
0.582 0.418 0.000
M49.8 Spondylopathy in other diseases classified elsewhere
0.579 0.421 0.000
M49.4 Neuropathic spondylopathy
0.579 0.421 0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere
0.579 0.421 0.000
M49.2 Enterobacterial spondylitis
0.579 0.421 0.000
M49.1 Brucella spondylitis
0.579 0.421 0.000
M49.0 Tuberculosis of spine
0.579 0.421 0.000
M89.8 Other specified disorders of bone
0.578 0.422 0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.577 0.423 0.000
M40.2 Other and unspecified kyphosis
0.574 0.426 0.000
I15.9 Seconday hypertension, unspecified
0.000 0.427 0.573
I15.8 Other secondary hypertension
0.000 0.427 0.573
I15.2 Hypertension secondary to endocrine disorders
0.000 0.427 0.573
I15.0 Renovascular hypertension
0.000 0.427 0.573
M79.18 Myalgia (Other)
0.573 0.427 0.000
M47.8 Other spondylosis
0.568 0.432 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.568 0.432 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.568 0.432 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.567 0.433 0.000
M16.5 Other posttraumatic coxarthrosis
0.566 0.434 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.566 0.434 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.565 0.435 0.000
M88 Paget's disease of bone [osteitis deformans]
0.564 0.435 0.000
M46.8 Other specified inflammatory spondylopathies
0.564 0.436 0.000
M46.5 Other infective spondylopathies
0.564 0.436 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.564 0.436 0.000
M46.2 Osteomyelitis of vertebra
0.564 0.436 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.564 0.436 0.000
M46.0 Spinal enthesopathy
0.564 0.436 0.000
M77.47 Metatarsalgia-Ankle/Foot
0.564 0.436 0.000
M86.6 Other chronic osteomyelitis
0.563 0.437 0.000
M24 Other specific joint derangements
0.561 0.438 0.000
M79.7 Fibromyalgia
0.560 0.440 0.000
M87.99 Osteonecrosis, unspecified (Site unspecified)
0.560 0.440 0.000
M87.98 Osteonecrosis, unspecified (Other)
0.560 0.440 0.000
M87.97 Osteonecrosis, unspecified (Ankle and foot)
0.560 0.440 0.000
M87.94 Osteonecrosis, unspecified (Hand)
0.560 0.440 0.000
M87.93 Osteonecrosis, unspecified (Forearm)
0.560 0.440 0.000
M87.92 Osteonecrosis, unspecified (Upper arm)
0.560 0.440 0.000
M87.90 Osteonecrosis, unspecified (Multiple sites)
0.560 0.440 0.000
M54.89 Other dorsalgia (Site unspecified)
0.559 0.441 0.000
M89.0 Algoneurodystrophy
0.559 0.441 0.000
M48.9 Spondylopathy, unspecified
0.557 0.442 0.000
M48.8 Other specified spondylopathies
0.557 0.442 0.000
M48.4 Fatigue fracture of vertebra
0.557 0.442 0.000
M48.3 Traumatic spondylopathy
0.557 0.442 0.000
M48.2 Kissing spine
0.557 0.442 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.557 0.442 0.000
M51 Other intervertebral disk disorders
0.557 0.443 0.000
M54.59 Low back pain (Site unspecified)
0.555 0.445 0.000
M53.9 Dorsopathy, unspecified
0.553 0.446 0.000
M53.8 Other specified dorsopathies
0.553 0.446 0.000
M53.2 Spinal instabilities
0.553 0.446 0.000
M53.1 Cervicobrachial syndrome
0.553 0.446 0.000
M53.0 Cervicocranial syndrome
0.553 0.446 0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)
0.552 0.448 0.000
M17.5 Other secondary gonarthrosis
0.552 0.448 0.000
M75.2 Bicipital tendinitis
0.551 0.449 0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)
0.550 0.450 0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)
0.550 0.450 0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)
0.550 0.450 0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)
0.550 0.450 0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)
0.550 0.450 0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)
0.550 0.450 0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)
0.550 0.450 0.000
M25.99 Joint disorder, unspecified (Site unspecified)
0.549 0.451 0.000
M25.98 Joint disorder, unspecified (Other)
0.549 0.451 0.000
M25.97 Joint disorder, unspecified (Ankle and foot)
0.549 0.451 0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)
0.549 0.451 0.000
M25.94 Joint disorder, unspecified (Hand)
0.549 0.451 0.000
M25.93 Joint disorder, unspecified (Forearm)
0.549 0.451 0.000
M25.92 Joint disorder, unspecified (Upper arm)
0.549 0.451 0.000
M25.91 Joint disorder, unspecified (Shoulder region)
0.549 0.451 0.000
M25.90 Joint disorder, unspecified (Multiple sites)
0.549 0.451 0.000
M79.9 Soft tissue disorder, unspecified
0.549 0.451 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.549 0.451 0.000
M79.3 Panniculitis, unspecified
0.549 0.451 0.000
M81.8 Other osteoporosis
0.549 0.451 0.000
M81.6 Localised osteoporosis [Lequesne]
0.549 0.451 0.000
M81.5 Idiopathic osteoporosis
0.549 0.451 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.549 0.451 0.000
M81.2 Osteoporosis of disuse
0.549 0.451 0.000
M81.1 Postoophorectomy osteoporosis
0.549 0.451 0.000
M81.0 Postmenopausal osteoporosis
0.549 0.451 0.000
M25.09 Haemarthrosis (Site unspecified)
0.549 0.451 0.000
M25.08 Haemarthrosis (Other)
0.549 0.451 0.000
M25.07 Haemarthrosis (Ankle and foot)
0.549 0.451 0.000
M25.05 Haemarthrosis (Pelvic region and thigh)
0.549 0.451 0.000
M25.04 Haemarthrosis (Hand)
0.549 0.451 0.000
M25.03 Haemarthrosis (Forearm)
0.549 0.451 0.000
M25.02 Haemarthrosis (Upper arm)
0.549 0.451 0.000
M25.01 Haemarthrosis (Shoulder region)
0.549 0.451 0.000
M25.00 Haemarthrosis (Multiple sites)
0.549 0.451 0.000
M25.34 Other instability of joint (Hand)
0.548 0.452 0.000
M86.5 Other chronic haematogenous osteomyelitis
0.548 0.452 0.000
M86.4 Chronic osteomyelitis with draining sinus
0.548 0.452 0.000
M86.3 Chronic multifocal osteomyelitis
0.548 0.452 0.000
M86.2 Subacute osteomyelitis
0.548 0.452 0.000
M86.1 Other acute osteomyelitis
0.548 0.452 0.000
M86.0 Acute haematogenous osteomyelitis
0.548 0.452 0.000
M76.8 Other enthesopathies of lower limb, excluding foot
0.548 0.452 0.000
M16.6 Other secondary coxarthrosis, bilateral
0.547 0.453 0.000
M16.4 Posttraumatic coxarthrosis, bilateral
0.547 0.453 0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral
0.547 0.453 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.546 0.454 0.000
M19.94 Arthrosis, unspecified (Hand)
0.546 0.454 0.000
M94.88 Other specified disorders of cartilage (Other)
0.545 0.454 0.000
M06.4 Inflammatory polyarthropathy
0.545 0.455 0.000
M94.9 Disorder of cartilage, unspecified
0.545 0.455 0.000
M94.3 Chondrolysis
0.545 0.455 0.000
M94.1 Relapsing polychondritis
0.545 0.455 0.000
M94.0 Chondrocostal junction syndrome [Tietze]
0.545 0.455 0.000
M23.5 Chronic instability of knee
0.545 0.455 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.545 0.455 0.000
M21.2 Flexion deformity
0.544 0.456 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.543 0.457 0.000
M47.82 Other spondylosis (Cervical region)
0.543 0.457 0.000
M87.2 Osteonecrosis due to previous trauma
0.542 0.458 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.542 0.458 0.000
M05 Seropositive rheumatoid arthritis
0.541 0.459 0.000
M79.15 Myalgia (Pelvic region and thigh)
0.540 0.460 0.000
M50.0 Cervical disk disorder with myelopathy
0.539 0.461 0.000
M46.4 Discitis, unspecified
0.538 0.462 0.000
M19.04 Primary arthrosis of other joints (Hand)
0.538 0.462 0.000
M54.47 Lumbago with sciatica (Lumbosacral region)
0.536 0.464 0.000
M25.31 Other instability of joint (Shoulder region)
0.536 0.464 0.000
M85.8 Other specified disorders of bone density and structure
0.535 0.465 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.535 0.465 0.000
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.466 0.534
M07.6 Other enteropathic arthropathies
0.534 0.466 0.000
M07.5 Arthropathy in ulcerative colitis
0.534 0.466 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.534 0.466 0.000
M07.2 Psoriatic spondylitis
0.534 0.466 0.000
M07.1 Arthritis mutilans
0.534 0.466 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.534 0.466 0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.531 0.469 0.000
M72 Fibroblastic disorders
0.498 0.469 0.033
M25.36 Other instability of joint (Lower leg)
0.530 0.470 0.000
M54.88 Other dorsalgia (Sacral and sacrococcygeal region)
0.529 0.471 0.000
M54.87 Other dorsalgia (Lumbosacral region)
0.529 0.471 0.000
M54.86 Other dorsalgia (Lumbar region)
0.529 0.471 0.000
M54.85 Other dorsalgia (Thoracolumbar region)
0.529 0.471 0.000
M54.84 Other dorsalgia (Thoracic region)
0.529 0.471 0.000
M54.83 Other dorsalgia (Cervicothoracic region)
0.529 0.471 0.000
M54.82 Other dorsalgia (Cervical region)
0.529 0.471 0.000
M54.81 Other dorsalgia (Occipito-atlanto-axial region)
0.529 0.471 0.000
M54.80 Other dorsalgia (Multiple sites in spine)
0.529 0.471 0.000
M81.4 Drug-induced osteoporosis
0.529 0.471 0.000
M77.49 Metatarsalgia-Site unspec
0.529 0.471 0.000
M77.48 Metatarsalgia-Other
0.529 0.471 0.000
M77.46 Metatarsalgia-Lower Leg
0.529 0.471 0.000
M77.45 Metatarsalgia-Pelvic/Thigh
0.529 0.471 0.000
M77.44 Metatarsalgia-Hand
0.529 0.471 0.000
M77.43 Metatarsalgia-Forearm
0.529 0.471 0.000
M77.42 Metatarsalgia-Upper arm
0.529 0.471 0.000
M77.41 Metatarsalgia-Shldr region
0.529 0.471 0.000
M77.40 Metatarsalgia-Mult sites
0.529 0.471 0.000
M85.6 Other cyst of bone
0.529 0.471 0.000
M23.3 Other meniscus derangements
0.528 0.472 0.000
M06.3 Rheumatoid nodule
0.527 0.472 0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)
0.524 0.476 0.000
M79.59 Residual foreign body in soft tissue (Site unspecified)
0.524 0.476 0.000
M79.58 Residual foreign body in soft tissue (Other)
0.524 0.476 0.000
M79.57 Residual foreign body in soft tissue (Ankle and foot)
0.524 0.476 0.000
M79.56 Residual foreign body in soft tissue (Lower leg)
0.524 0.476 0.000
M79.55 Residual foreign body in soft tissue (Pelvic region and thigh)
0.524 0.476 0.000
M79.53 Residual foreign body in soft tissue (Forearm)
0.524 0.476 0.000
M79.52 Residual foreign body in soft tissue (Upper arm)
0.524 0.476 0.000
M79.51 Residual foreign body in soft tissue (Shoulder region)
0.524 0.476 0.000
M79.50 Residual foreign body in soft tissue (Multiple sites)
0.524 0.476 0.000
M79.2 Neuralgia and neuritis, unspecified
0.521 0.479 0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)
0.521 0.479 0.000
M41.8 Other forms of scoliosis
0.520 0.479 0.000
M41.5 Other secondary scoliosis
0.519 0.481 0.000
M41.4 Neuromuscular scoliosis
0.519 0.481 0.000
M41.3 Thoracogenic scoliosis
0.519 0.481 0.000
M41.2 Other idiopathic scoliosis
0.519 0.481 0.000
M41.1 Juvenile idiopathic scoliosis
0.519 0.481 0.000
M41.0 Infantile idiopathic scoliosis
0.519 0.481 0.000
M06.8 Other specified rheumatoid arthritis
0.518 0.482 0.000
M06.2 Rheumatoid bursitis
0.518 0.482 0.000
M06.1 Adult-onset Still's disease
0.518 0.482 0.000
M93.8 Other specified osteochondropathies
0.518 0.482 0.000
M93.2 Osteochondritis dissecans
0.518 0.482 0.000
M93.1 Kienbock's disease of adults
0.518 0.482 0.000
M93.0 Slipped upper femoral epiphysis (nontraumatic)
0.518 0.482 0.000
M13.98 Arthritis, unspecified (Other)
0.517 0.483 0.000
M47.1 Other spondylosis with myelopathy
0.516 0.484 0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)
0.515 0.485 0.000
M30.8 Other conditions related to polyarteritis nodosa
0.514 0.486 0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
0.514 0.486 0.000
M30.2 Juvenile polyarteritis
0.514 0.486 0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.514 0.486 0.000
M30.0 Polyarteritis nodosa
0.514 0.486 0.000
M32.9 Systemic lupus erythematosus, unspecified
0.514 0.486 0.000
M32.8 Other forms of systemic lupus erythematosus
0.514 0.486 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.514 0.486 0.000
M32.0 Drug-induced systemic lupus erythematosus
0.514 0.486 0.000
M33.9 Dermatopolymyositis, unspecified
0.514 0.486 0.000
M33.2 Polymyositis
0.514 0.486 0.000
M33.1 Other dermatomyositis
0.514 0.486 0.000
M33.0 Juvenile dermatomyositis
0.514 0.486 0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere
0.514 0.486 0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere
0.514 0.486 0.000
M36.3 Arthropathy in other blood disorders
0.514 0.486 0.000
M36.2 Haemophilic arthropathy
0.514 0.486 0.000
M36.1 Arthropathy in neoplastic disease
0.514 0.486 0.000
M36.0 Dermato(poly)myositis in neoplastic disease
0.514 0.486 0.000
M73.8 Other soft tissue disorders in diseases classified elsewhere
0.514 0.486 0.000
M73.1 Syphilitic bursitis
0.514 0.486 0.000
M73.0 Gonococcal bursitis
0.514 0.486 0.000
M75.81 Other shoulder lesions, right shoulder
0.514 0.486 0.000
M89.6 Osteopathy after poliomyelitis
0.513 0.487 0.000
M89.4 Other hypertrophic osteo-arthropathy
0.513 0.487 0.000
M89.3 Hypertrophy of bone
0.513 0.487 0.000
M89.2 Other disorders of bone development and growth
0.513 0.487 0.000
M89.1 Epiphyseal arrest
0.513 0.487 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.513 0.487 0.000
M25.39 Other instability of joint (Site unspecified)
0.512 0.488 0.000
M25.38 Other instability of joint (Other)
0.512 0.488 0.000
M25.35 Other instability of joint (Pelvic region and thigh)
0.512 0.488 0.000
M25.33 Other instability of joint (Forearm)
0.512 0.488 0.000
M25.32 Other instability of joint (Upper arm)
0.512 0.488 0.000
M25.30 Other instability of joint (Multiple sites)
0.512 0.488 0.000
M25.19 Fistula of joint (Site unspecified)
0.511 0.489 0.000
M25.18 Fistula of joint (Other)
0.511 0.489 0.000
M25.17 Fistula of joint (Ankle and foot)
0.511 0.489 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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