TreeWAS – Variant ID: rs13182402

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K60.1 Chronic anal fissure	0.049	0.951	0.000
K60.2 Anal fissure, unspecified	0.047	0.953	0.000
K60 Fissure and fistula of anal and rectal regions	0.046	0.954	0.000
K60.3 Anal fistula	0.040	0.960	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.036	0.964	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.033	0.967	0.000
K60.0 Acute anal fissure	0.032	0.967	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.029	0.971	0.000
K60.4 Rectal fistula	0.029	0.971	0.000
K60.5 Anorectal fistula	0.028	0.972	0.000
T42.1 Iminostilbenes	0.027	0.973	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.027	0.973	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.027	0.973	0.000
T42.0 Hydantoin derivatives	0.026	0.974	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.026	0.974	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.026	0.974	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.025	0.975	0.000
T39.0 Salicylates	0.024	0.976	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.024	0.976	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.024	0.976	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.024	0.976	0.000
T42.3 Barbiturates	0.024	0.976	0.000
T42.2 Succinimides and oxazolidinediones	0.024	0.976	0.000
T42.4 Benzodiazepines	0.024	0.976	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.024	0.976	0.000
T40.2 Other opioids	0.023	0.977	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.023	0.977	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.022	0.978	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.021	0.979	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.021	0.979	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.021	0.979	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.021	0.979	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.021	0.979	0.000
T40.6 Other and unspecified narcotics	0.020	0.980	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.020	0.980	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.020	0.980	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.020	0.980	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.020	0.980	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.020	0.980	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.020	0.980	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.020	0.980	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.020	0.980	0.000
T44.0 Anticholinesterase agents	0.020	0.980	0.000
T36 Poisoning by systemic antibiotics	0.020	0.980	0.000
T43.2 Other and unspecified antidepressants	0.019	0.981	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.019	0.981	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.019	0.981	0.000
T46.7 Peripheral vasodilators	0.019	0.981	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.019	0.981	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.019	0.981	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.019	0.981	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.019	0.981	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.019	0.981	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.019	0.981	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.018	0.981	0.000
T40.8 Lysergide [LSD]	0.018	0.981	0.000
T40.7 Cannabis (derivatives)	0.018	0.981	0.000
T40.5 Cocaine	0.018	0.981	0.000
T40.3 Methadone	0.018	0.981	0.000
T40.1 Heroin	0.018	0.981	0.000
T40.0 Opium	0.018	0.981	0.000
T46.1 Calcium-channel blockers	0.018	0.982	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.018	0.982	0.000
T39.4 Antirheumatics, not elsewhere classified	0.018	0.982	0.000
T39.2 Pyrazolone derivatives	0.018	0.982	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.017	0.983	0.000
T40.4 Other synthetic narcotics	0.016	0.983	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.016	0.984	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.016	0.984	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.016	0.984	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.016	0.984	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.016	0.984	0.000
T47.7 Emetics	0.016	0.984	0.000
T47.6 Antidiarrhoeal drugs	0.016	0.984	0.000
T47.5 Digestants	0.016	0.984	0.000
T47.4 Other laxatives	0.016	0.984	0.000
T47.3 Saline and osmotic laxatives	0.016	0.984	0.000
T47.2 Stimulant laxatives	0.016	0.984	0.000
T47.0 Histamine H(2)-receptor antagonists	0.016	0.984	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.015	0.984	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.015	0.984	0.000
T37.5 Antiviral drugs	0.015	0.984	0.000
T37.4 Anthelminthics	0.015	0.984	0.000
T37.3 Other antiprotozoal drugs	0.015	0.984	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.015	0.984	0.000
T37.1 Antimycobacterial drugs	0.015	0.984	0.000
T37.0 Sulphonamides	0.015	0.984	0.000
T41.5 Therapeutic gases	0.015	0.984	0.000
T41.4 Anaesthetic, unspecified	0.015	0.984	0.000
T41.3 Local anaesthetics	0.015	0.984	0.000
T41.2 Other and unspecified general anaesthetics	0.015	0.984	0.000
T41.1 Intravenous anaesthetics	0.015	0.984	0.000
T41.0 Inhaled anaesthetics	0.015	0.984	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.015	0.984	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.015	0.984	0.000
T48.5 Anti-common-cold drugs	0.015	0.984	0.000
T48.4 Expectorants	0.015	0.984	0.000
T48.3 Antitussives	0.015	0.984	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.015	0.984	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.015	0.984	0.000
T48.0 Oxytocic drugs	0.015	0.984	0.000
T49.9 Topical agent, unspecified	0.015	0.984	0.000
T49.8 Other topical agents	0.015	0.984	0.000
T49.7 Dental drugs, topically applied	0.015	0.984	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.015	0.984	0.000
T49.5 Ophthalmological drugs and preparations	0.015	0.984	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.015	0.984	0.000
T49.3 Emollients, demulcents and protectants	0.015	0.984	0.000
T49.2 Local astringents and local detergents	0.015	0.984	0.000
T49.1 Antipruritics	0.015	0.984	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.015	0.984	0.000
T43.9 Psychotropic drug, unspecified	0.015	0.985	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.015	0.985	0.000
T43.6 Psychostimulants with abuse potential	0.015	0.985	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.015	0.985	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.015	0.985	0.000
T38.1 Thyroid hormones and substitutes	0.015	0.985	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.015	0.985	0.000
T36.9 Systemic antibiotic, unspecified	0.014	0.986	0.000
T36.8 Other systemic antibiotics	0.014	0.986	0.000
T36.7 Antifungal antibiotics, systemically used	0.014	0.986	0.000
T36.6 Rifamycins	0.014	0.986	0.000
T36.5 Aminoglycosides	0.014	0.986	0.000
T36.4 Tetracyclines	0.014	0.986	0.000
T36.3 Macrolides	0.014	0.986	0.000
T36.2 Chloramphenicol group	0.014	0.986	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.014	0.986	0.000
T38.9 Other and unspecified hormone antagonists	0.014	0.986	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.014	0.986	0.000
T38.7 Androgens and anabolic congeners	0.014	0.986	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.014	0.986	0.000
T38.5 Other oestrogens and progestogens	0.014	0.986	0.000
T38.4 Oral contraceptives	0.014	0.986	0.000
T38.2 Antithyroid drugs	0.014	0.986	0.000
T38.0 Glucocorticoids and synthetic analogues	0.014	0.986	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.013	0.986	0.000
T45.8 Other primarily systemic and haematological agents	0.013	0.986	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.013	0.986	0.000
T45.6 Fibrinolysis-affecting drugs	0.013	0.986	0.000
T45.4 Iron and its compounds	0.013	0.986	0.000
T45.3 Enzymes, not elsewhere classified	0.013	0.986	0.000
T45.2 Vitamins, not elsewhere classified	0.013	0.986	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.013	0.987	0.000
T39.1 4-Aminophenol derivatives	0.013	0.987	0.000
T36.0 Penicillins	0.012	0.987	0.000
T45.5 Anticoagulants	0.012	0.987	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.012	0.988	0.000
T50.8 Diagnostic agents	0.012	0.988	0.000
T50.7 Analeptics and opioid receptor antagonists	0.012	0.988	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.012	0.988	0.000
T50.5 Appetite depressants	0.012	0.988	0.000
T50.4 Drugs affecting uric acid metabolism	0.012	0.988	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.012	0.988	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.012	0.988	0.000
T50.1 Loop [high-ceiling] diuretics	0.012	0.988	0.000
T50.0 Mineralocorticoids and their antagonists	0.012	0.988	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.011	0.989	0.000
N30.1 Interstitial cystitis (chronic)	0.000	0.989	0.011
T43.0 Tricyclic and tetracyclic antidepressants	0.011	0.989	0.000
T45.0 Antiallergic and antiemetic drugs	0.010	0.989	0.000
H90.5 Sensorineural hearing loss, unspecified	0.011	0.989	0.000
N30.8 Other cystitis	0.000	0.990	0.010
N30 Cystitis	0.000	0.990	0.010
N30.2 Other chronic cystitis	0.000	0.991	0.009
N30.0 Acute cystitis	0.000	0.991	0.009
H90 Conductive and sensorineural hearing loss	0.009	0.991	0.000
M23.30 Other meniscus derangements (Multiple sites)	0.009	0.991	0.000
N30.9 Cystitis, unspecified	0.000	0.992	0.008
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.008	0.992	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.008	0.992	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.008	0.992	0.000
K35.9 Acute appendicitis, unspecified	0.008	0.992	0.000
H90.3 Sensorineural hearing loss, bilateral	0.008	0.992	0.000
F41.1 Generalised anxiety disorder	0.008	0.992	0.000
M23.3 Other meniscus derangements	0.007	0.993	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.007	0.993	0.000
Z99.8 Dependence on other enabling machines and devices	0.007	0.993	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.007	0.993	0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.007	0.993	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.007	0.993	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.006	0.994	0.000
N30.4 Irradiation cystitis	0.000	0.994	0.006
S02.8 Fractures of other skull and facial bones	0.006	0.994	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.006	0.994	0.000
H90.0 Conductive hearing loss, bilateral	0.006	0.994	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.006	0.994	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.006	0.994	0.000
S06 Intracranial injury	0.006	0.994	0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.006	0.994	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.006	0.994	0.000
S06.5 Traumatic subdural haemorrhage	0.006	0.994	0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.006	0.994	0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.006	0.994	0.000
N30.3 Trigonitis	0.000	0.994	0.006
F41 Other anxiety disorders	0.006	0.994	0.000
M23.37 Other meniscus derangements-Capsular lig	0.006	0.994	0.000
S06.8 Other intracranial injuries	0.006	0.994	0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.005	0.995	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.005	0.995	0.000
T51 Toxic effect of alcohol	0.005	0.995	0.000
T51.0 Ethanol	0.005	0.995	0.000
T51.9 Alcohol, unspecified	0.005	0.995	0.000
M65.34 Trigger finger-Hand	0.000	0.995	0.005
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.005	0.995	0.000
S06.2 Diffuse brain injury	0.005	0.995	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.005	0.995	0.000
S02 Fracture of skull and facial bones	0.005	0.995	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.005	0.995	0.000
S02.4 Fracture of malar and maxillary bones	0.005	0.995	0.000
F41.2 Mixed anxiety and depressive disorder	0.005	0.995	0.000
S02.81 Fractures of other skull and facial bones (open)	0.005	0.995	0.000
F43.2 Adjustment disorders	0.005	0.995	0.000
Z83.3 Family history of diabetes mellitus	0.000	0.995	0.005
F43 Reaction to severe stress, and adjustment disorders	0.005	0.995	0.000
T79.3 Post-traumatic wound infection, not elsewhere classified	0.005	0.995	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.005	0.995	0.000
S06.0 Concussion	0.004	0.995	0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.004	0.995	0.000
S06.7 Intracranial injury with prolonged coma	0.004	0.995	0.000
S06.1 Traumatic cerebral oedema	0.004	0.995	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.004	0.995	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.004	0.995	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.004	0.995	0.000
S06.4 Epidural haemorrhage	0.004	0.996	0.000
F41.8 Other specified anxiety disorders	0.004	0.996	0.000
F41.3 Other mixed anxiety disorders	0.004	0.996	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.004	0.996	0.000
S06.9 Intracranial injury, unspecified	0.004	0.996	0.000
G37 Other demyelinating diseases of central nervous system	0.004	0.996	0.000
S06.81 Other intracranial injuries (with open intracranial wound)	0.004	0.996	0.000
F43.1 Posttraumatic stress disorder	0.004	0.996	0.000
S02.7 Multiple fractures involving skull and facial bones	0.004	0.996	0.000
S06.3 Focal brain injury	0.004	0.996	0.000
F43.9 Reaction to severe stress, unspecified	0.004	0.996	0.000
S02.3 Fracture of orbital floor	0.004	0.996	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.004	0.996	0.000
T51.8 Other alcohols	0.004	0.996	0.000
T51.3 Fusel oil	0.004	0.996	0.000
T51.2 2-Propanol	0.004	0.996	0.000
T51.1 Methanol	0.004	0.996	0.000
D61.9 Aplastic anaemia, unspecified	0.000	0.996	0.004
S46.3 Injury of muscle and tendon of triceps	0.004	0.996	0.000
Z83.5 Family history of eye and ear disorders	0.000	0.996	0.004
S06.21 Diffuse brain injury (with open intracranial wound)	0.004	0.996	0.000
S40-S49 Injuries to the shoulder and upper arm	0.004	0.996	0.000
H90.2 Conductive hearing loss, unspecified	0.004	0.996	0.000
S00-S09 Injuries to the head	0.004	0.996	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.004	0.996	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.004	0.996	0.000
S02.0 Fracture of vault of skull	0.004	0.996	0.000
T79-T79 Certain early complications of trauma	0.004	0.996	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.004	0.996	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.004	0.996	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.004	0.996	0.000
S46.0 Injury of tendon of the rotator cuff of shoulder	0.004	0.996	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.004	0.996	0.000
T63 Toxic effect of contact with venomous animals	0.004	0.996	0.000
Z83 Family history of other specific disorders	0.000	0.996	0.004
F40-F48 Neurotic, stress-related and somatoform disorders	0.004	0.996	0.000
F43.8 Other reactions to severe stress	0.003	0.996	0.000
F43.0 Acute stress reaction	0.004	0.996	0.000
S02.1 Fracture of base of skull	0.003	0.996	0.000
S06.01 Concussion (with open intracranial wound)	0.003	0.996	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.003	0.996	0.000
S06.00 Concussion (without open intracranial wound)	0.003	0.996	0.000
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.003	0.996	0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.003	0.996	0.000
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.003	0.996	0.000
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.003	0.996	0.000
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot	0.003	0.996	0.000
S06.41 Epidural haemorrhage (with open intracranial wound)	0.003	0.997	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.003	0.997	0.000
S02.30 Fracture of orbital floor (closed)	0.003	0.997	0.000
S02.5 Fracture of tooth	0.003	0.997	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.003	0.997	0.000
K35 Acute appendicitis	0.003	0.997	0.000
T65 Toxic effect of other and unspecified substances	0.003	0.997	0.000
T62 Toxic effect of other noxious substances eaten as food	0.003	0.997	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.003	0.997	0.000
T60 Toxic effect of pesticides	0.003	0.997	0.000
T57 Toxic effect of other inorganic substances	0.003	0.997	0.000
T56 Toxic effect of metals	0.003	0.997	0.000
T54 Toxic effect of corrosive substances	0.003	0.997	0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.003	0.997	0.000
T52 Toxic effect of organic solvents	0.003	0.997	0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.003	0.997	0.000
T55 Toxic effect of soaps and detergents	0.003	0.997	0.000
K35.2 Acute appendicitis with generalized peritonitis	0.003	0.997	0.000
Z83.7 Family history of diseases of the digestive system	0.000	0.997	0.003
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.003	0.997	0.000
G37.5 Concentric sclerosis [Balo]	0.003	0.997	0.000
G37.4 Subacute necrotising myelitis	0.003	0.997	0.000
G37.2 Central pontine myelinolysis	0.003	0.997	0.000
G37.1 Central demyelination of corpus callosum	0.003	0.997	0.000
G37.0 Diffuse sclerosis	0.003	0.997	0.000
N42.8 Other specified disorders of prostate	0.003	0.997	0.000
Q44.6 Cystic disease of liver	0.003	0.997	0.000
R04.0 Epistaxis	0.000	0.997	0.003
S41 Open wound of shoulder and upper arm	0.003	0.997	0.000
S40 Superficial injury of shoulder and upper arm	0.003	0.997	0.000
T00-T07 Injuries involving multiple body regions	0.003	0.997	0.000
S02.71 Multiple fractures involving skull and facial bones (open)	0.003	0.997	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.003	0.997	0.000
T59 Toxic effect of other gases, fumes and vapours	0.003	0.997	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.003	0.997	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.003	0.997	0.000
T21 Burn and corrosion of trunk	0.003	0.997	0.000
S02.31 Fracture of orbital floor (open)	0.003	0.997	0.000
S02.2 Fracture of nasal bones	0.003	0.997	0.000
S46.9 Injury of unspecified muscle and tendon at shoulder and upper arm level	0.003	0.997	0.000
S46.8 Injury of other muscles and tendons at shoulder and upper arm level	0.003	0.997	0.000
S46.7 Injury of multiple muscles and tendons at shoulder and upper arm level	0.003	0.997	0.000
S46.1 Injury of muscle and tendon of long head of biceps	0.003	0.997	0.000
S70-S79 Injuries to the hip and thigh	0.003	0.997	0.000
O46.9 Antepartum haemorrhage, unspecified	0.000	0.997	0.003
T15-T19 Effects of foreign body entering through natural orifice	0.003	0.997	0.000
T63.4 Venom of other arthropods	0.003	0.997	0.000
S46.2 Injury of muscle and tendon of other parts of biceps	0.003	0.997	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.003	0.997	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.003	0.997	0.000
S48 Traumatic amputation of shoulder and upper arm	0.003	0.997	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.003	0.997	0.000
S44 Injury of nerves at shoulder and upper arm level	0.003	0.997	0.000
S47 Crushing injury of shoulder and upper arm	0.003	0.997	0.000
S08 Traumatic amputation of part of head	0.003	0.997	0.000
S07 Crushing injury of head	0.003	0.997	0.000
S04 Injury of cranial nerves	0.003	0.997	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.003	0.997	0.000
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.003	0.997	0.000
T33-T35 Frostbite	0.003	0.997	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.003	0.997	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.003	0.997	0.000
S02.6 Fracture of mandible	0.003	0.997	0.000
T85.4 Mechanical complication of breast prosthesis and implant	0.000	0.997	0.003
Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.997	0.003
S02.01 Fracture of vault of skull (open)	0.003	0.997	0.000
S40.8 Other superficial injuries of shoulder and upper arm	0.003	0.997	0.000
F44 Dissociative [conversion] disorders	0.003	0.997	0.000
T20 Burn and corrosion of head and neck	0.003	0.997	0.000
T25 Burn and corrosion of ankle and foot	0.003	0.997	0.000
M79.67 Pain in limb (Ankle and foot)	0.000	0.997	0.003
T79.9 Unspecified early complication of trauma	0.003	0.997	0.000
T79.5 Traumatic anuria	0.003	0.997	0.000
T79.4 Traumatic shock	0.003	0.997	0.000
T79.2 Traumatic secondary and recurrent haemorrhage	0.003	0.997	0.000
T79.1 Fat embolism (traumatic)	0.003	0.997	0.000
T79.0 Air embolism (traumatic)	0.003	0.997	0.000
T11 Other injuries of upper limb, level unspecified	0.003	0.997	0.000
S10-S19 Injuries to the neck	0.003	0.997	0.000
T16 Foreign body in ear	0.003	0.997	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.003	0.997	0.000
K35.8 Acute appendicitis, other and unspecified	0.003	0.997	0.000
S41.1 Open wound of upper arm	0.003	0.997	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.003	0.997	0.000
T63.9 Toxic effect of contact with unspecified venomous animal	0.003	0.997	0.000
T63.8 Toxic effect of contact with other venomous animals	0.003	0.997	0.000
T63.6 Toxic effect of contact with other marine animals	0.003	0.997	0.000
T63.5 Toxic effect of contact with fish	0.003	0.997	0.000
T63.3 Venom of spider	0.003	0.997	0.000
T63.2 Venom of scorpion	0.003	0.997	0.000
T63.1 Venom of other reptiles	0.003	0.997	0.000
T63.0 Snake venom	0.003	0.997	0.000
S02.00 Fracture of vault of skull (closed)	0.003	0.997	0.000
T21.0 Burn of unspecified degree of trunk	0.003	0.997	0.000
Z83.0 Family history of human immunodeficiency virus [HIV]	0.000	0.997	0.003
S79 Other and unspecified injuries of hip and thigh	0.003	0.997	0.000
S02.11 Fracture of base of skull (open)	0.003	0.997	0.000
E66.8 Other obesity	0.000	0.997	0.003
Q38-Q45 Other congenital malformations of the digestive system	0.003	0.997	0.000
T24.7 Corrosion of third degree of hip and lower limb, except ankle and foot	0.003	0.997	0.000
T24.6 Corrosion of second degree of hip and lower limb, except ankle and foot	0.003	0.997	0.000
T24.5 Corrosion of first degree of hip and lower limb, except ankle and foot	0.003	0.997	0.000
T24.4 Corrosion of unspecified degree of hip and lower limb, except ankle and foot	0.003	0.997	0.000
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.003	0.997	0.000
T24.2 Burn of second degree of hip and lower limb, except ankle and foot	0.003	0.997	0.000
T24.1 Burn of first degree of hip and lower limb, except ankle and foot	0.003	0.997	0.000
T00 Superficial injuries involving multiple body regions	0.003	0.997	0.000
T58 Toxic effect of carbon monoxide	0.003	0.997	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.003	0.997	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.003	0.997	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.003	0.997	0.000
T02 Fractures involving multiple body regions	0.003	0.997	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.003	0.997	0.000
T13 Other injuries of lower limb, level unspecified	0.003	0.997	0.000
K35.1 Acute appendicitis with peritoneal abscess	0.003	0.997	0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.003	0.997	0.000
S02.51 Fracture of tooth (open)	0.003	0.997	0.000
S70.1 Contusion of thigh	0.003	0.997	0.000
T18 Foreign body in alimentary tract	0.003	0.997	0.000
F10.1 Harmful use	0.000	0.997	0.003
T11.0 Superficial injury of upper limb, level unspecified	0.003	0.997	0.000
Q39 Congenital malformations of oesophagus	0.003	0.997	0.000
T52.9 Organic solvent, unspecified	0.002	0.997	0.000
T52.8 Other organic solvents	0.002	0.997	0.000
T52.4 Ketones	0.002	0.997	0.000
T52.3 Glycols	0.002	0.997	0.000
T52.2 Homologues of benzene	0.002	0.997	0.000
T52.1 Benzene	0.002	0.997	0.000
T52.0 Petroleum products	0.002	0.997	0.000
T53.9 Halogen derivative of aliphatic and aromatic hydrocarbons, unspecified	0.002	0.997	0.000
T53.7 Other halogen derivatives of aromatic hydrocarbons	0.002	0.997	0.000
T53.6 Other halogen derivatives of aliphatic hydrocarbons	0.002	0.997	0.000
T53.5 Chlorofluorocarbons	0.002	0.997	0.000
T53.4 Dichloromethane	0.002	0.997	0.000
T53.3 Tetrachloroethylene	0.002	0.997	0.000
T53.2 Trichloroethylene	0.002	0.997	0.000
T53.1 Chloroform	0.002	0.997	0.000
T53.0 Carbon tetrachloride	0.002	0.997	0.000
T54.9 Corrosive substance, unspecified	0.002	0.997	0.000
T54.3 Corrosive alkalis and alklali-like substances	0.002	0.997	0.000
T54.2 Corrosive acids and acid-like substances	0.002	0.997	0.000
T54.1 Other corrosive organic compounds	0.002	0.997	0.000
T54.0 Phenol and phenol homologues	0.002	0.997	0.000
T56.9 Metal, unspecified	0.002	0.997	0.000
T56.8 Other metals	0.002	0.997	0.000
T56.7 Beryllium and its compounds	0.002	0.997	0.000
T56.6 Tin and its compounds	0.002	0.997	0.000
T56.5 Zinc and its compounds	0.002	0.997	0.000
T56.4 Copper and its compounds	0.002	0.997	0.000
T56.3 Cadmium and its compounds	0.002	0.997	0.000
T56.2 Chromium and its compounds	0.002	0.997	0.000
T56.1 Mercury and its compounds	0.002	0.997	0.000
T56.0 Lead and its compounds	0.002	0.997	0.000
T57.9 Inorganic substance, unspecified	0.002	0.997	0.000
T57.8 Other specified inorganic substances	0.002	0.997	0.000
T57.3 Hydrogen cyanide	0.002	0.997	0.000
T57.2 Manganese and its compounds	0.002	0.997	0.000
T57.1 Phosphorus and its compounds	0.002	0.997	0.000
T57.0 Arsenic and its compounds	0.002	0.997	0.000
T60.9 Pesticide, unspecified	0.002	0.997	0.000
T60.8 Other pesticides	0.002	0.997	0.000
T60.4 Rodenticides	0.002	0.997	0.000
T60.3 Herbicides and fungicides	0.002	0.997	0.000
T60.2 Other insecticides	0.002	0.997	0.000
T60.1 Halogenated insecticides	0.002	0.997	0.000
T60.0 Organophosphate and carbamate insecticides	0.002	0.997	0.000
T61.9 Toxic effect of unspecified seafood	0.002	0.997	0.000
T61.8 Toxic effect of other seafoods	0.002	0.997	0.000
T61.2 Other fish and shellfish poisoning	0.002	0.997	0.000
T61.1 Scombroid fish poisoning	0.002	0.997	0.000
T61.0 Ciguatera fish poisoning	0.002	0.997	0.000
T62.9 Noxious substance eaten as food, unspecified	0.002	0.997	0.000
T62.8 Other specified noxious substances eaten as food	0.002	0.997	0.000
T62.2 Other ingested (parts of) plant(s)	0.002	0.997	0.000
T62.1 Ingested berries	0.002	0.997	0.000
T62.0 Ingested mushrooms	0.002	0.997	0.000
T65.9 Toxic effect of unspecified substance	0.002	0.997	0.000
T65.8 Toxic effect of other specified substances	0.002	0.997	0.000
T65.6 Paints and dyes, not elsewhere classified	0.002	0.997	0.000
T65.5 Nitroglycerin and other nitric acids and esters	0.002	0.997	0.000
T65.4 Carbon disulphide	0.002	0.997	0.000
T65.3 Nitroderivatives and aminoderivatives of benzene and its homologues	0.002	0.997	0.000
T65.2 Tobacco and nicotine	0.002	0.997	0.000
T65.1 Strychnine and its salts	0.002	0.997	0.000
T65.0 Cyanides	0.002	0.997	0.000
T79.8 Other early complications of trauma	0.003	0.997	0.000
Z83.6 Family history of diseases of the respiratory system	0.000	0.997	0.003
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.002	0.997	0.000
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.003	0.997	0.000
F48 Other neurotic disorders	0.003	0.997	0.000
T98 Sequelae of other and unspecified effects of external causes	0.003	0.997	0.000
S40.7 Multiple superficial injuries of shoulder and upper arm	0.003	0.997	0.000
S41.8 Open wound of other and unspecified parts of shoulder girdle	0.002	0.997	0.000
S41.7 Multiple open wounds of shoulder and upper arm	0.002	0.997	0.000
S41.0 Open wound of shoulder	0.002	0.997	0.000
T20.0 Burn of unspecified degree of head and neck	0.003	0.997	0.000
Z83.1 Family history of other infectious and parasitic diseases	0.000	0.997	0.003
S70 Superficial injury of hip and thigh	0.003	0.997	0.000
T06 Other injuries involving multiple body regions, not elsewhere classified	0.002	0.997	0.000
T05 Traumatic amputations involving multiple body regions	0.002	0.997	0.000
T04 Crushing injuries involving multiple body regions	0.002	0.997	0.000
T03 Dislocations, sprains and strains involving multiple body regions	0.002	0.997	0.000
T01 Open wounds involving multiple body regions	0.002	0.997	0.000
T07 Unspecified multiple injuries	0.002	0.997	0.000
T59.9 Gases, fumes and vapours, unspecified	0.002	0.997	0.000
T59.7 Carbon dioxide	0.002	0.997	0.000
T59.6 Hydrogen sulphide	0.002	0.997	0.000
T59.5 Fluorine gas and hydrogen fluoride	0.002	0.997	0.000
T59.4 Chlorine gas	0.002	0.997	0.000
T59.3 Lachrymogenic gas	0.002	0.997	0.000
T59.2 Formaldehyde	0.002	0.997	0.000
T59.1 Sulphur dioxide	0.002	0.997	0.000
T59.0 Nitrogen oxides	0.002	0.997	0.000
T98.1 Sequelae of other and unspecified effects of external causes	0.003	0.997	0.000
T09 Other injuries of spine and trunk, level unspecified	0.002	0.997	0.000
T12.X1 Fracture of lower limb, level unspecified (open)	0.002	0.997	0.000
T12.X0 Fracture of lower limb, level unspecified (closed)	0.002	0.997	0.000
T12 Fracture of lower limb, level unspecified	0.002	0.997	0.000
T10.X1 Fracture of upper limb, level unspecified (open)	0.002	0.997	0.000
T10.X0 Fracture of upper limb, level unspecified (closed)	0.002	0.997	0.000
T10 Fracture of upper limb, level unspecified	0.002	0.997	0.000
T08.X1 Fracture of spine, level unspecified (open)	0.002	0.997	0.000
T08.X0 Fracture of spine, level unspecified (closed)	0.002	0.997	0.000
T08 Fracture of spine, level unspecified	0.002	0.997	0.000
M23 Internal derangement of knee	0.003	0.997	0.000
Q43 Other congenital malformations of intestine	0.003	0.997	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.003	0.997	0.000
S71 Open wound of hip and thigh	0.003	0.997	0.000
S02.21 Fracture of nasal bones (open)	0.002	0.997	0.000
T21.7 Corrosion of third degree of trunk	0.002	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations