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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs13212534
log Bayes Factor = 117.616
Chromosome 6   position 25,983,010  (GRCh37) Explore rs13212534 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
D64.9 Anaemia, unspecified
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
1.000 0.000 0.000
D64 Other anaemias
1.000 0.000 0.000
D60-D64 Aplastic and other anaemias
1.000 0.000 0.000
M06 Other rheumatoid arthritis
0.999 0.001 0.000
M06.9 Rheumatoid arthritis, unspecified
0.999 0.001 0.000
N40 Hyperplasia of prostate
0.000 0.001 0.999
E20-E35 Disorders of other endocrine glands
0.998 0.002 0.000
E70-E90 Metabolic disorders
0.998 0.002 0.000
N40-N51 Diseases of male genital organs
0.000 0.002 0.998
E27 Other disorders of adrenal gland
0.997 0.003 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.997 0.003 0.000
E27.1 Primary adrenocortical insufficiency
0.996 0.004 0.000
E16 Other disorders of pancreatic internal secretion
0.995 0.005 0.000
M15-M19 Arthrosis
0.995 0.005 0.000
M17 Gonarthrosis [arthrosis of knee]
0.995 0.005 0.000
N20 Calculus of kidney and ureter
0.000 0.005 0.995
Chapter XIV Diseases of the genitourinary system
0.000 0.005 0.995
N20-N23 Urolithiasis
0.000 0.005 0.995
N20.0 Calculus of kidney
0.000 0.006 0.994
M35 Other systemic involvement of connective tissue
0.994 0.006 0.000
R31 Unspecified haematuria
0.000 0.007 0.993
E16.2 Hypoglycaemia, unspecified
0.993 0.007 0.000
N30-N39 Other diseases of urinary system
0.000 0.008 0.992
Chapter XII Diseases of the skin and subcutaneous tissue
0.991 0.009 0.000
N42 Other disorders of prostate
0.000 0.009 0.991
M35.0 Sicca syndrome [Sjogren]
0.991 0.009 0.000
N32 Other disorders of bladder
0.000 0.009 0.991
E10.3 With ophthalmic complications
0.991 0.009 0.000
N32.0 Bladder-neck obstruction
0.000 0.012 0.988
D50-D53 Nutritional anaemias
0.987 0.013 0.000
L20-L30 Dermatitis and eczema
0.987 0.013 0.000
M17.9 Gonarthrosis, unspecified
0.987 0.013 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.987 0.013 0.000
E83 Disorders of mineral metabolism
0.980 0.016 0.004
M34 Systemic sclerosis
0.983 0.017 0.000
K90 Intestinal malabsorption
0.982 0.018 0.001
D50 Iron deficiency anaemia
0.980 0.020 0.000
Chapter VII Diseases of the eye and adnexa
0.979 0.021 0.000
N20.1 Calculus of ureter
0.000 0.021 0.979
M17.0 Primary gonarthrosis, bilateral
0.975 0.025 0.000
M24 Other specific joint derangements
0.974 0.026 0.000
M23 Internal derangement of knee
0.972 0.028 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.970 0.030 0.000
E83.5 Disorders of calcium metabolism
0.967 0.033 0.000
D50.9 Iron deficiency anaemia, unspecified
0.966 0.034 0.000
M22 Disorders of patella
0.964 0.036 0.000
E78.5 Hyperlipidaemia, unspecified
0.962 0.038 0.000
D80-D89 Certain disorders involving the immune mechanism
0.959 0.041 0.000
L50-L54 Urticaria and erythema
0.958 0.042 0.000
M65-M68 Disorders of synovium and tendon
0.952 0.048 0.000
E10.1 With ketoacidosis
0.949 0.051 0.000
H30-H36 Disorders of choroid and retina
0.949 0.051 0.000
L30 Other dermatitis
0.948 0.052 0.000
N42.8 Other specified disorders of prostate
0.000 0.054 0.946
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.946 0.054 0.000
E10.2 With renal complications
0.945 0.055 0.000
N42.1 Congestion and haemorrhage of prostate
0.000 0.056 0.944
L27 Dermatitis due to substances taken internally
0.939 0.061 0.000
M70-M79 Other soft tissue disorders
0.937 0.063 0.000
K90-K93 Other diseases of the digestive system
0.923 0.064 0.013
E05.0 Thyrotoxicosis with diffuse goitre
0.934 0.066 0.000
E50-E64 Other nutritional deficiencies
0.933 0.067 0.000
D86 Sarcoidosis
0.933 0.067 0.000
Chapter II Neoplasms
0.932 0.068 0.000
Chapter XI Diseases of the digestive system
0.918 0.068 0.014
H36 Retinal disorders in diseases classified elsewhere
0.930 0.070 0.000
M72 Fibroblastic disorders
0.929 0.071 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.927 0.073 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.924 0.076 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.921 0.079 0.000
M10 Gout
0.919 0.081 0.000
H36.0 Diabetic retinopathy
0.917 0.083 0.000
M34.9 Systemic sclerosis, unspecified
0.916 0.084 0.000
N32.8 Other specified disorders of bladder
0.000 0.085 0.915
L30.9 Dermatitis, unspecified
0.912 0.088 0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.000 0.093 0.907
D50.8 Other iron deficiency anaemias
0.907 0.093 0.000
D86.9 Sarcoidosis, unspecified
0.906 0.094 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.906 0.094 0.000
M31 Other necrotising vasculopathies
0.905 0.095 0.000
H43-H45 Disorders of vitreous body and globe
0.905 0.095 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.901 0.099 0.000
C43 Malignant melanoma of skin
0.901 0.099 0.000
M11 Other crystal arthropathies
0.894 0.106 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.892 0.108 0.000
M34.1 CR(E)ST syndrome
0.889 0.111 0.000
M24.1 Other articular cartilage disorders
0.886 0.114 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.883 0.117 0.000
C15-C26 Malignant neoplasms of digestive organs
0.882 0.118 0.000
E78.1 Pure hyperglyceridaemia
0.882 0.118 0.000
N32.3 Diverticulum of bladder
0.000 0.121 0.879
Chapter XX External causes of morbidity and mortality
0.876 0.124 0.000
K40 Inguinal hernia
0.001 0.127 0.872
M22.3 Other derangements of patella
0.872 0.128 0.000
E10.5 With peripheral circulatory complications
0.871 0.129 0.000
E11 Non-insulin-dependent diabetes mellitus
0.870 0.130 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.000 0.132 0.868
M24.4 Recurrent dislocation and subluxation of joint
0.868 0.132 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.867 0.133 0.000
L27.0 Generalised skin eruption due to drugs and medicaments
0.866 0.134 0.000
M67 Other disorders of synovium and tendon
0.862 0.138 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.862 0.138 0.000
M86-M90 Other osteopathies
0.861 0.138 0.000
L28 Lichen simplex chronicus and prurigo
0.861 0.139 0.000
Chapter V Mental and behavioural disorders
0.861 0.139 0.000
D69 Purpura and other haemorrhagic conditions
0.859 0.141 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.858 0.142 0.000
E53 Deficiency of other B group vitamins
0.857 0.143 0.000
H43 Disorders of vitreous body
0.857 0.143 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.855 0.145 0.000
E78.6 Lipoprotein deficiency
0.854 0.146 0.000
L50 Urticaria
0.853 0.147 0.000
M65 Synovitis and tenosynovitis
0.852 0.148 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.851 0.149 0.000
N00-N08 Glomerular diseases
0.000 0.149 0.851
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.849 0.151 0.000
H53-H54 Visual disturbances and blindness
0.846 0.154 0.000
W00-W19 Falls
0.846 0.154 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.844 0.156 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.843 0.157 0.000
M22.8 Other disorders of patella
0.843 0.157 0.000
C15 Malignant neoplasm of oesophagus
0.843 0.157 0.000
N36 Other disorders of urethra
0.000 0.157 0.843
E23 Hypofunction and other disorders of pituitary gland
0.842 0.158 0.000
N34 Urethritis and urethral syndrome
0.000 0.161 0.839
K70-K77 Diseases of liver
0.836 0.162 0.001
M23.3 Other meniscus derangements
0.837 0.163 0.000
M34.8 Other forms of systemic sclerosis
0.834 0.166 0.000
E83.4 Disorders of magnesium metabolism
0.831 0.168 0.001
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.831 0.169 0.000
L52 Erythema nodosum
0.831 0.169 0.000
E10.8 With unspecified complications
0.830 0.170 0.000
C43.6 Malignant melanoma of upper limb, including shoulder
0.830 0.170 0.000
M10.0 Idiopathic gout
0.829 0.171 0.000
H43.1 Vitreous haemorrhage
0.829 0.171 0.000
M60-M63 Disorders of muscles
0.828 0.172 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.828 0.172 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.828 0.172 0.000
L10-L14 Bullous disorders
0.827 0.172 0.000
E14 Unspecified diabetes mellitus
0.827 0.173 0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.000 0.174 0.826
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.825 0.175 0.000
L53 Other erythematous conditions
0.824 0.176 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.818 0.182 0.000
M11.2 Other chondrocalcinosis
0.818 0.182 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.817 0.183 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.816 0.184 0.000
K90.9 Intestinal malabsorption, unspecified
0.813 0.186 0.000
E10.6 With other specified complications
0.812 0.188 0.000
L27.1 Localised skin eruption due to drugs and medicaments
0.811 0.189 0.000
M76 Enthesopathies of lower limb, excluding foot
0.811 0.189 0.000
H54 Blindness and low vision
0.810 0.190 0.000
M23.4 Loose body in knee
0.809 0.191 0.000
M25 Other joint disorders, not elsewhere classified
0.807 0.193 0.000
E88 Other metabolic disorders
0.806 0.194 0.000
D50.1 Sideropenic dysphagia
0.806 0.194 0.000
D55-D59 Haemolytic anaemias
0.805 0.195 0.000
K75 Other inflammatory liver diseases
0.805 0.195 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.805 0.195 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.805 0.195 0.000
L23 Allergic contact dermatitis
0.804 0.196 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.803 0.197 0.000
K40-K46 Hernia
0.012 0.198 0.790
E27.3 Drug-induced adrenocortical insufficiency
0.802 0.198 0.000
N02 Recurrent and persistent haematuria
0.000 0.199 0.801
M07 Psoriatic and enteropathic arthropathies
0.800 0.200 0.000
H34 Retinal vascular occlusions
0.799 0.201 0.000
M22.2 Patellofemoral disorders
0.799 0.201 0.000
N32.1 Vesicointestinal fistula
0.000 0.202 0.798
E11.3 With ophthalmic complications
0.797 0.203 0.000
C43.5 Malignant melanoma of trunk
0.797 0.203 0.000
N42.9 Disorder of prostate, unspecified
0.000 0.204 0.796
E27.2 Addisonian crisis
0.795 0.205 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.795 0.205 0.000
C25 Malignant neoplasm of pancreas
0.795 0.205 0.000
M31.6 Other giant cell arteritis
0.791 0.209 0.000
E84 Cystic fibrosis
0.790 0.210 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.789 0.211 0.000
K44 Diaphragmatic hernia
0.004 0.213 0.783
M14 Arthropathies in other diseases classified elsewhere
0.787 0.213 0.000
M00-M03 Infectious arthropathies
0.786 0.214 0.000
C43.4 Malignant melanoma of scalp and neck
0.786 0.214 0.000
E16.1 Other hypoglycaemia
0.786 0.214 0.000
H46 Optic neuritis
0.786 0.214 0.000
C43.9 Malignant melanoma of skin, unspecified
0.785 0.215 0.000
E73 Lactose intolerance
0.785 0.215 0.000
M17.3 Other posttraumatic gonarthrosis
0.785 0.215 0.000
C18 Malignant neoplasm of colon
0.781 0.219 0.000
C15.9 Oesophagus, unspecified
0.780 0.220 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.779 0.221 0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.000 0.222 0.778
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.778 0.222 0.000
W19 Unspecified fall
0.778 0.222 0.000
N49.2 Inflammatory disorders of scrotum
0.000 0.224 0.775
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.775 0.224 0.000
E10.0 With coma
0.772 0.228 0.000
K75.4 Autoimmune hepatitis
0.770 0.229 0.000
M86 Osteomyelitis
0.770 0.230 0.000
M67.8 Other specified disorders of synovium and tendon
0.770 0.230 0.000
M33 Dermatopolymyositis
0.769 0.231 0.000
E78.2 Mixed hyperlipidaemia
0.769 0.231 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.768 0.232 0.000
L50.0 Allergic urticaria
0.768 0.232 0.000
E53.8 Deficiency of other specified B group vitamins
0.767 0.233 0.000
M10.07 Idiopathic gout (Ankle and foot)
0.765 0.235 0.000
M11.26 Other chondrocalcinosis (Lower leg)
0.763 0.237 0.000
E20 Hypoparathyroidism
0.762 0.238 0.000
N02.9 Unspecified
0.000 0.239 0.761
X20-X29 Contact with venomous animals and plants
0.760 0.240 0.000
M25.9 Joint disorder, unspecified
0.759 0.241 0.000
F05.9 Delirium, unspecified
0.759 0.241 0.000
C83.3 Large cell (diffuse)
0.758 0.242 0.000
E78.4 Other hyperlipidaemia
0.758 0.242 0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.757 0.243 0.000
D64.8 Other specified anaemias
0.756 0.244 0.000
E10.4 With neurological complications
0.756 0.244 0.000
C43.3 Malignant melanoma of other and unspecified parts of face
0.756 0.244 0.000
M24.2 Disorder of ligament
0.755 0.245 0.000
C18.9 Colon, unspecified
0.755 0.245 0.000
M10.9 Gout, unspecified
0.753 0.247 0.000
H31 Other disorders of choroid
0.753 0.247 0.000
M06.4 Inflammatory polyarthropathy
0.752 0.248 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.751 0.249 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.751 0.249 0.000
M17.1 Other primary gonarthrosis
0.750 0.250 0.000
M23.1 Discoid meniscus (congenital)
0.749 0.251 0.000
M23.9 Internal derangement of knee, unspecified
0.749 0.251 0.000
M23.0 Cystic meniscus
0.747 0.253 0.000
N03 Chronic nephritic syndrome
0.000 0.254 0.746
M24.0 Loose body in joint
0.746 0.254 0.000
M23.5 Chronic instability of knee
0.745 0.254 0.000
L40-L45 Papulosquamous disorders
0.745 0.255 0.000
M17.5 Other secondary gonarthrosis
0.745 0.255 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.744 0.256 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.744 0.256 0.000
Z46.6 Fitting and adjustment of urinary device
0.000 0.256 0.744
N42.0 Calculus of prostate
0.000 0.256 0.744
F80-F89 Disorders of psychological development
0.743 0.257 0.000
M32 Systemic lupus erythematosus
0.743 0.257 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.742 0.258 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.741 0.259 0.000
D86.3 Sarcoidosis of skin
0.739 0.261 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.739 0.261 0.000
L28.1 Prurigo nodularis
0.739 0.261 0.000
L30.8 Other specified dermatitis
0.736 0.264 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.736 0.264 0.000
W19.9 Unspecified place
0.736 0.264 0.000
J98 Other respiratory disorders
0.736 0.264 0.000
N36.2 Urethral caruncle
0.000 0.265 0.735
E24 Cushing's syndrome
0.734 0.266 0.000
E74 Other disorders of carbohydrate metabolism
0.734 0.266 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.734 0.266 0.000
J95-J99 Other diseases of the respiratory system
0.733 0.267 0.000
C82.2 Large cell, follicular
0.732 0.268 0.000
N21 Calculus of lower urinary tract
0.000 0.268 0.732
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.731 0.269 0.000
V20-V29 Motorcycle rider injured in transport accident
0.731 0.269 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.731 0.269 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.729 0.271 0.000
Chapter X Diseases of the respiratory system
0.729 0.271 0.000
E61 Deficiency of other nutrient elements
0.729 0.271 0.000
M15 Polyarthrosis
0.728 0.272 0.000
W05 Fall involving wheelchair
0.728 0.272 0.000
M18 Arthrosis of first carpometacarpal joint
0.728 0.272 0.000
K35-K38 Diseases of appendix
0.722 0.273 0.006
M89 Other disorders of bone
0.727 0.273 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.727 0.273 0.000
C15.4 Middle third of oesophagus
0.725 0.275 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.724 0.276 0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)
0.724 0.276 0.000
K72 Hepatic failure, not elsewhere classified
0.723 0.276 0.001
F03 Unspecified dementia
0.723 0.277 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.720 0.280 0.000
M76.6 Achilles tendinitis
0.720 0.280 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.720 0.280 0.000
H30 Chorioretinal inflammation
0.719 0.280 0.000
D69.6 Thrombocytopenia, unspecified
0.719 0.281 0.000
H34.2 Other retinal artery occlusions
0.719 0.281 0.000
J98.4 Other disorders of lung
0.718 0.282 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.718 0.282 0.000
E10.7 With multiple complications
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E55 Vitamin D deficiency
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.1 Congenital hypothyroidism without goitre
0.717 0.283 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.717 0.283 0.000
M12 Other specific arthropathies
0.717 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.717 0.283 0.000
M08 Juvenile arthritis
0.717 0.283 0.000
D64.4 Congenital dyserythropoietic anaemia
0.717 0.283 0.000
D64.3 Other sideroblastic anaemias
0.717 0.283 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.717 0.283 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.717 0.283 0.000
D64.0 Hereditary sideroblastic anaemia
0.717 0.283 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.717 0.283 0.000
N48 Other disorders of penis
0.000 0.283 0.717
H25-H28 Disorders of lens
0.716 0.284 0.000
M06.8 Other specified rheumatoid arthritis
0.716 0.284 0.000
M06.2 Rheumatoid bursitis
0.716 0.284 0.000
M06.1 Adult-onset Still's disease
0.716 0.284 0.000
C85.1 B-cell lymphoma, unspecified
0.716 0.284 0.000
M25.7 Osteophyte
0.716 0.284 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.716 0.284 0.000
E32 Diseases of thymus
0.716 0.284 0.000
E31 Polyglandular dysfunction
0.716 0.284 0.000
E30 Disorders of puberty, not elsewhere classified
0.716 0.284 0.000
E25 Adrenogenital disorders
0.716 0.284 0.000
E79 Disorders of purine and pyrimidine metabolism
0.715 0.285 0.000
E77 Disorders of glycoprotein metabolism
0.715 0.285 0.000
E76 Disorders of glycosaminoglycan metabolism
0.715 0.285 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.715 0.285 0.000
E72 Other disorders of amino-acid metabolism
0.715 0.285 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.715 0.285 0.000
E70 Disorders of aromatic amino-acid metabolism
0.715 0.285 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.715 0.285 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.000 0.285 0.715
N44 Torsion of testis
0.000 0.285 0.715
E27.5 Adrenomedullary hyperfunction
0.715 0.285 0.000
E27.0 Other adrenocortical overactivity
0.715 0.285 0.000
E15 Nondiabetic hypoglycaemic coma
0.715 0.285 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.715 0.285 0.000
M06.3 Rheumatoid nodule
0.714 0.286 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.713 0.286 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.713 0.286 0.000
E16.4 Abnormal secretion of gastrin
0.713 0.286 0.000
E16.3 Increased secretion of glucagon
0.713 0.286 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.713 0.286 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.713 0.286 0.000
M67.4 Ganglion
0.713 0.287 0.000
M62 Other disorders of muscle
0.713 0.287 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.000 0.287 0.713
L21 Seborrhoeic dermatitis
0.713 0.287 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.712 0.288 0.000
M35.8 Other specified systemic involvement of connective tissue
0.712 0.288 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.712 0.288 0.000
M35.5 Multifocal fibrosclerosis
0.712 0.288 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.712 0.288 0.000
M35.2 Behcet's disease
0.712 0.288 0.000
E13 Other specified diabetes mellitus
0.712 0.288 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.712 0.288 0.000
E11.5 With peripheral circulatory complications
0.711 0.289 0.000
N37 Urethral disorders in diseases classified elsewhere
0.000 0.289 0.711
N33 Bladder disorders in diseases classified elsewhere
0.000 0.289 0.711
F99-F99 Unspecified mental disorder
0.711 0.289 0.000
N42.3 Dysplasia of prostate
0.000 0.289 0.711
E05.8 Other thyrotoxicosis
0.710 0.289 0.000
N32.4 Rupture of bladder, nontraumatic
0.000 0.289 0.710
N32.2 Vesical fistula, not elsewhere classified
0.000 0.289 0.710
E11.6 With other specified complications
0.710 0.290 0.000
E53.9 Vitamin B deficiency, unspecified
0.710 0.290 0.000
N23 Unspecified renal colic
0.000 0.290 0.710
W07 Fall involving chair
0.710 0.290 0.000
H54.4 Blindness, one eye
0.710 0.290 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.000 0.290 0.710
D83 Common variable immunodeficiency
0.709 0.291 0.000
D84 Other immunodeficiencies
0.709 0.291 0.000
E29 Testicular dysfunction
0.708 0.292 0.000
F02 Dementia in other diseases classified elsewhere
0.708 0.292 0.000
N34.2 Other urethritis
0.000 0.292 0.708
W50-W64 Exposure to animate mechanical forces
0.708 0.292 0.000
K90.8 Other intestinal malabsorption
0.708 0.292 0.001
M80-M85 Disorders of bone density and structure
0.708 0.292 0.000
L24 Irritant contact dermatitis
0.708 0.292 0.000
L26 Exfoliative dermatitis
0.708 0.292 0.000
L22 Diaper [napkin] dermatitis
0.708 0.292 0.000
N36.0 Urethral fistula
0.000 0.292 0.708
D53 Other nutritional anaemias
0.707 0.292 0.000
E78.3 Hyperchylomicronaemia
0.707 0.293 0.000
N46 Male infertility
0.000 0.293 0.706
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)
0.706 0.294 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.703 0.294 0.003
E83.8 Other disorders of mineral metabolism
0.703 0.294 0.003
E83.2 Disorders of zinc metabolism
0.703 0.294 0.003
E83.0 Disorders of copper metabolism
0.703 0.294 0.003
M24.7 Protrusio acetabuli
0.705 0.295 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.705 0.295 0.000
M34.0 Progressive systemic sclerosis
0.705 0.295 0.000
M24.11 Other articular cartilage disorders (Shoulder region)
0.705 0.295 0.000
K90.3 Pancreatic steatorrhoea
0.704 0.295 0.001
K90.2 Blind loop syndrome, not elsewhere classified
0.704 0.295 0.001
K90.1 Tropical sprue
0.704 0.295 0.001
E23.2 Diabetes insipidus
0.704 0.296 0.000
C92 Myeloid leukaemia
0.704 0.296 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.704 0.296 0.000
D62 Acute posthaemorrhagic anaemia
0.702 0.298 0.000
N42.2 Atrophy of prostate
0.000 0.298 0.702
D69.4 Other primary thrombocytopenia
0.702 0.298 0.000
D52 Folate deficiency anaemia
0.699 0.301 0.000
L20 Atopic dermatitis
0.699 0.301 0.000
L53.8 Other specified erythematous conditions
0.699 0.301 0.000
M24.9 Joint derangement, unspecified
0.698 0.302 0.000
M24.6 Ankylosis of joint
0.698 0.302 0.000
C07 Malignant neoplasm of parotid gland
0.697 0.303 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.697 0.303 0.000
H54.7 Unspecified visual loss
0.695 0.305 0.000
O36 Maternal care for other known or suspected foetal problems
0.695 0.305 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.695 0.305 0.000
D86.0 Sarcoidosis of lung
0.695 0.305 0.000
W06 Fall involving bed
0.694 0.306 0.000
L25 Unspecified contact dermatitis
0.693 0.306 0.000
C95 Leukaemia of unspecified cell type
0.693 0.307 0.000
N03.9 Unspecified
0.000 0.308 0.692
M23.49 Loose body in knee-Unspec lig/men
0.692 0.308 0.000
M22.1 Recurrent subluxation of patella
0.691 0.309 0.000
M22.9 Disorder of patella, unspecified
0.691 0.309 0.000
M22.0 Recurrent dislocation of patella
0.691 0.309 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.691 0.309 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.691 0.309 0.000
M86.9 Osteomyelitis, unspecified
0.690 0.310 0.000
C81 Hodgkin's disease
0.689 0.311 0.000
L51 Erythema multiforme
0.688 0.312 0.000
D82 Immunodeficiency associated with other major defects
0.687 0.313 0.000
D81 Combined immunodeficiencies
0.687 0.313 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.687 0.313 0.000
L54 Erythema in diseases classified elsewhere
0.687 0.313 0.000
E11.0 With coma
0.687 0.313 0.000
E11.1 With ketoacidosis
0.686 0.314 0.000
K75.9 Inflammatory liver disease, unspecified
0.685 0.315 0.000
M21 Other acquired deformities of limbs
0.685 0.315 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.684 0.316 0.000
C01 Malignant neoplasm of base of tongue
0.684 0.316 0.000
M24.5 Contracture of joint
0.683 0.317 0.000
H43.9 Disorder of vitreous body, unspecified
0.683 0.317 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.683 0.317 0.000
E23.7 Disorder of pituitary gland, unspecified
0.683 0.317 0.000
L28.0 Lichen simplex chronicus
0.682 0.318 0.000
C25.9 Pancreas, unspecified
0.682 0.318 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.680 0.320 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.680 0.320 0.000
M22.4 Chondromalacia patellae
0.680 0.320 0.000
L30.5 Pityriasis alba
0.679 0.321 0.000
L30.4 Erythema intertrigo
0.679 0.321 0.000
L30.3 Infective dermatitis
0.679 0.321 0.000
L30.2 Cutaneous autosensitisation
0.679 0.321 0.000
L30.1 Dyshidrosis [pompholyx]
0.679 0.321 0.000
L30.0 Nummular dermatitis
0.679 0.321 0.000
M66 Spontaneous rupture of synovium and tendon
0.679 0.321 0.000
E22 Hyperfunction of pituitary gland
0.679 0.321 0.000
M13 Other arthritis
0.679 0.321 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.678 0.322 0.000
C05 Malignant neoplasm of palate
0.677 0.323 0.000
X23 Contact with hornets, wasps and bees
0.677 0.323 0.000
F01 Vascular dementia
0.676 0.324 0.000
M71 Other bursopathies
0.676 0.324 0.000
D61 Other aplastic anaemias
0.676 0.324 0.000
L53.0 Toxic erythema
0.674 0.326 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.673 0.327 0.000
L27.9 Dermatitis due to unspecified substance taken internally
0.673 0.327 0.000
L27.8 Dermatitis due to other substances taken internally
0.673 0.327 0.000
L27.2 Dermatitis due to ingested food
0.673 0.327 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.672 0.328 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.662 0.329 0.010
D51 Vitamin B12 deficiency anaemia
0.671 0.329 0.000
E11.9 Without complications
0.671 0.329 0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)
0.670 0.330 0.000
M23.8 Other internal derangements of knee
0.670 0.330 0.000
W13 Fall from, out of or through building or structure
0.670 0.330 0.000
F05.8 Other delirium
0.669 0.331 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.669 0.331 0.000
E63 Other nutritional deficiencies
0.669 0.331 0.000
E56 Other vitamin deficiencies
0.669 0.331 0.000
E51 Thiamine deficiency
0.669 0.331 0.000
E50 Vitamin A deficiency
0.669 0.331 0.000
E60 Dietary zinc deficiency
0.669 0.331 0.000
E59 Dietary selenium deficiency
0.669 0.331 0.000
E58 Dietary calcium deficiency
0.669 0.331 0.000
E54 Ascorbic acid deficiency
0.669 0.331 0.000
E52 Niacin deficiency [pellagra]
0.669 0.331 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.669 0.331 0.000
K73 Chronic hepatitis, not elsewhere classified
0.668 0.331 0.001
E40-E46 Malnutrition
0.669 0.331 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.669 0.331 0.000
H43.2 Crystalline deposits in vitreous body
0.668 0.331 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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