TreeWAS – Variant ID: rs13219957

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
F03 Unspecified dementia	0.084	0.916	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.073	0.927	0.000
F05 Delirium, not induced by alcohol and other psychoactive substances	0.065	0.935	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.064	0.936	0.000
F00 Dementia in Alzheimer's disease	0.059	0.941	0.000
F06.7 Mild cognitive disorder	0.057	0.943	0.000
F09 Unspecified organic or symptomatic mental disorder	0.057	0.943	0.000
F05.0 Delirium not superimposed on dementia, so described	0.053	0.947	0.000
F01 Vascular dementia	0.053	0.947	0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.052	0.948	0.000
F05.8 Other delirium	0.051	0.949	0.000
F05.1 Delirium superimposed on dementia	0.050	0.950	0.000
F05.9 Delirium, unspecified	0.050	0.950	0.000
F02 Dementia in other diseases classified elsewhere	0.050	0.950	0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.049	0.951	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.049	0.951	0.000
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease	0.047	0.952	0.000
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease	0.046	0.954	0.000
F06.6 Organic emotionally labile [asthenic] disorder	0.046	0.954	0.000
F06.5 Organic dissociative disorder	0.046	0.954	0.000
F06.4 Organic anxiety disorder	0.046	0.954	0.000
F06.3 Organic mood [affective] disorders	0.046	0.954	0.000
F06.2 Organic delusional [schizophrenia-like] disorder	0.046	0.954	0.000
F06.1 Organic catatonic disorder	0.046	0.954	0.000
F06.0 Organic hallucinosis	0.046	0.954	0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.045	0.955	0.000
F00.1 Dementia in Alzheimer's disease with late onset	0.042	0.958	0.000
F01.9 Vascular dementia, unspecified	0.038	0.962	0.000
F01.8 Other vascular dementia	0.038	0.962	0.000
F01.3 Mixed cortical and subcortical vascular dementia	0.038	0.962	0.000
F01.2 Subcortical vascular dementia	0.038	0.962	0.000
F01.1 Multi-infarct dementia	0.038	0.962	0.000
F01.0 Vascular dementia of acute onset	0.038	0.962	0.000
F00.0 Dementia in Alzheimer's disease with early onset	0.037	0.963	0.000
F02.8 Dementia in other specified diseases classified elsewhere	0.037	0.963	0.000
F02.4 Dementia in human immunodeficiency virus [HIV] disease	0.036	0.964	0.000
F02.2 Dementia in Huntington's disease	0.036	0.964	0.000
F02.1 Dementia in Creutzfeldt-Jakob disease	0.036	0.964	0.000
F07.9 Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction	0.035	0.964	0.000
F07.8 Other organic personality and behavioural disorders due to brain disease, damage and dysfunction	0.035	0.964	0.000
F07.1 Postencephalitic syndrome	0.035	0.964	0.000
F07.0 Organic personality disorder	0.035	0.964	0.000
F02.0 Dementia in Pick's disease	0.035	0.965	0.000
F02.3 Dementia in Parkinson's disease	0.033	0.966	0.000
F07.2 Postconcussional syndrome	0.033	0.967	0.000
E83.1 Disorders of iron metabolism	0.000	0.989	0.011
K50.1 Crohn's disease of large intestine	0.008	0.992	0.000
Q21.0 Ventricular septal defect	0.007	0.993	0.000
Q21 Congenital malformations of cardiac septa	0.007	0.993	0.000
K22.2 Oesophageal obstruction	0.000	0.994	0.006
Q21.8 Other congenital malformations of cardiac septa	0.006	0.994	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.006	0.994	0.000
O36.5 Maternal care for poor foetal growth	0.006	0.994	0.000
Q21.3 Tetralogy of Fallot	0.006	0.994	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.006	0.994	0.000
Q24 Other congenital malformations of heart	0.005	0.994	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.005	0.995	0.000
Q21.4 Aortopulmonary septal defect	0.005	0.995	0.000
Q21.2 Atrioventricular septal defect	0.005	0.995	0.000
Q28 Other congenital malformations of circulatory system	0.005	0.995	0.000
Q25 Congenital malformations of great arteries	0.005	0.995	0.000
T83.0 Mechanical complication of urinary (indwelling) catheter	0.005	0.995	0.000
Z99.1 Dependence on respirator	0.005	0.995	0.000
Q26 Congenital malformations of great veins	0.004	0.995	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.004	0.995	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.004	0.995	0.000
Q27 Other congenital malformations of peripheral vascular system	0.005	0.995	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.004	0.996	0.000
N48.6 Balanitis xerotica obliterans	0.000	0.996	0.004
Q24.0 Dextrocardia	0.004	0.996	0.000
S64.2 Injury of radial nerve at wrist and hand level	0.004	0.996	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.004	0.996	0.000
Q25.0 Patent ductus arteriosus	0.004	0.996	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.004	0.996	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.000	0.996	0.004
Q24.8 Other specified congenital malformations of heart	0.004	0.996	0.000
Q24.6 Congenital heart block	0.004	0.996	0.000
Q24.4 Congenital subaortic stenosis	0.004	0.996	0.000
Q24.3 Pulmonary infundibular stenosis	0.004	0.996	0.000
Q24.2 Cor triatriatum	0.004	0.996	0.000
Q24.1 Levocardia	0.004	0.996	0.000
Q28.3 Other malformations of cerebral vessels	0.004	0.996	0.000
T83.3 Mechanical complication of intra-uterine contraceptive device	0.004	0.996	0.000
G70.0 Myasthenia gravis	0.004	0.996	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.004	0.996	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.004	0.996	0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.004	0.996	0.000
Q18 Other congenital malformations of face and neck	0.004	0.996	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.004	0.996	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.004	0.996	0.000
Q28.1 Other malformations of precerebral vessels	0.004	0.996	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.004	0.996	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.004	0.996	0.000
Q23 Congenital malformations of aortic and mitral valves	0.004	0.996	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.004	0.996	0.000
Q24.5 Malformation of coronary vessels	0.004	0.996	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.004	0.996	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.004	0.996	0.000
Q25.8 Other congenital malformations of great arteries	0.004	0.996	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.004	0.996	0.000
Q25.6 Stenosis of pulmonary artery	0.004	0.996	0.000
Q25.5 Atresia of pulmonary artery	0.004	0.996	0.000
Q25.4 Other congenital malformations of aorta	0.004	0.996	0.000
Q25.3 Stenosis of aorta	0.004	0.996	0.000
Q25.2 Atresia of aorta	0.004	0.996	0.000
Q18.0 Sinus, fistula and cyst of branchial cleft	0.004	0.996	0.000
O14.9 Preeclampsia, unspecified	0.004	0.996	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.004	0.996	0.000
Q00-Q07 Congenital malformations of the nervous system	0.004	0.996	0.000
A04.7 Enterocolitis due to Clostridium difficile	0.000	0.996	0.004
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.003	0.996	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.003	0.996	0.000
Q20.6 Isomerism of atrial appendages	0.003	0.996	0.000
Q20.5 Discordant atrioventricular connexion	0.003	0.996	0.000
Q20.4 Double inlet ventricle	0.003	0.996	0.000
Q20.3 Discordant ventriculoarterial connexion	0.003	0.996	0.000
Q20.2 Double outlet left ventricle	0.003	0.996	0.000
Q20.1 Double outlet right ventricle	0.003	0.996	0.000
Q20.0 Common arterial trunk	0.003	0.996	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.003	0.996	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.003	0.996	0.000
Q22.6 Hypoplastic right heart syndrome	0.003	0.996	0.000
Q22.5 Ebstein's anomaly	0.003	0.996	0.000
Q22.4 Congenital tricuspid stenosis	0.003	0.996	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.003	0.996	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.003	0.996	0.000
Q22.1 Congenital pulmonary valve stenosis	0.003	0.996	0.000
Q22.0 Pulmonary valve atresia	0.003	0.996	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.003	0.996	0.000
Q26.8 Other congenital malformations of great veins	0.003	0.996	0.000
Q26.6 Portal vein-hepatic artery fistula	0.003	0.996	0.000
Q26.5 Anomalous portal venous connexion	0.003	0.996	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.003	0.996	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.003	0.996	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.003	0.996	0.000
Q26.1 Persistent left superior vena cava	0.003	0.996	0.000
Q26.0 Congenital stenosis of vena cava	0.003	0.996	0.000
A49.0 Staphylococcal infection, unspecified	0.004	0.996	0.000
Q27.4 Congenital phlebectasia	0.003	0.996	0.000
Q27.2 Other congenital malformations of renal artery	0.003	0.996	0.000
Q27.1 Congenital renal artery stenosis	0.003	0.996	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.003	0.996	0.000
A04.5 Campylobacter enteritis	0.000	0.996	0.004
T21 Burn and corrosion of trunk	0.004	0.996	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.003	0.996	0.000
Q50-Q56 Congenital malformations of genital organs	0.003	0.996	0.000
Q15 Other congenital malformations of eye	0.003	0.996	0.000
Q12 Congenital lens malformations	0.003	0.996	0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum	0.004	0.996	0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.003	0.996	0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.003	0.997	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.003	0.997	0.000
Q25.1 Coarctation of aorta	0.003	0.997	0.000
Q14 Congenital malformations of posterior segment of eye	0.003	0.997	0.000
O14.1 Severe preeclampsia	0.003	0.997	0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.003	0.997	0.000
T83.2 Mechanical complication of graft of urinary organ	0.003	0.997	0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.003	0.997	0.000
O14.0 Moderate preeclampsia	0.003	0.997	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.003	0.997	0.000
Q35-Q37 Cleft lip and cleft palate	0.003	0.997	0.000
T21.3 Burn of third degree of trunk	0.003	0.997	0.000
Q78 Other osteochondrodysplasias	0.003	0.997	0.000
Q23.0 Congenital stenosis of aortic valve	0.003	0.997	0.000
T20 Burn and corrosion of head and neck	0.003	0.997	0.000
W19.2 School, other institution and public administrative area	0.003	0.997	0.000
Q17 Other congenital malformations of ear	0.003	0.997	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.003	0.997	0.000
Q13 Congenital malformations of anterior segment of eye	0.003	0.997	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.003	0.997	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.003	0.997	0.000
T20.1 Burn of first degree of head and neck	0.003	0.997	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.003	0.997	0.000
Q54 Hypospadias	0.003	0.997	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.003	0.997	0.000
N76.2 Acute vulvitis	0.003	0.997	0.000
Q18.1 Preauricular sinus and cyst	0.003	0.997	0.000
Q76 Congenital malformations of spine and bony thorax	0.003	0.997	0.000
T21.2 Burn of second degree of trunk	0.003	0.997	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.003	0.997	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.003	0.997	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.003	0.997	0.000
Q05 Spina bifida	0.003	0.997	0.000
Q68 Other congenital musculoskeletal deformities	0.003	0.997	0.000
Q18.9 Congenital malformation of face and neck, unspecified	0.003	0.997	0.000
Q18.8 Other specified congenital malformations of face and neck	0.003	0.997	0.000
Q18.7 Microcheilia	0.003	0.997	0.000
Q18.6 Macrocheilia	0.003	0.997	0.000
Q18.5 Microstomia	0.003	0.997	0.000
Q18.4 Macrostomia	0.003	0.997	0.000
Q18.3 Webbing of neck	0.003	0.997	0.000
Q18.2 Other branchial cleft malformations	0.003	0.997	0.000
R09.1 Pleurisy	0.003	0.997	0.000
T21.0 Burn of unspecified degree of trunk	0.003	0.997	0.000
Q30 Congenital malformations of nose	0.003	0.997	0.000
Q67.5 Congenital deformity of spine	0.003	0.997	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.003	0.997	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.003	0.997	0.000
Q23.4 Hypoplastic left heart syndrome	0.003	0.997	0.000
Q23.3 Congenital mitral insufficiency	0.003	0.997	0.000
Q23.2 Congenital mitral stenosis	0.003	0.997	0.000
T20.0 Burn of unspecified degree of head and neck	0.003	0.997	0.000
N90.4 Leukoplakia of vulva	0.003	0.997	0.000
Q27.3 Peripheral arteriovenous malformation	0.003	0.997	0.000
Q78.0 Osteogenesis imperfecta	0.003	0.997	0.000
Q52 Other congenital malformations of female genitalia	0.003	0.997	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.000	0.997	0.003
Q55 Other congenital malformations of male genital organs	0.003	0.997	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.003	0.997	0.000
Q75 Other congenital malformations of skull and face bones	0.003	0.997	0.000
Q73 Reduction defects of unspecified limb	0.003	0.997	0.000
Q72 Reduction defects of lower limb	0.003	0.997	0.000
Q71 Reduction defects of upper limb	0.003	0.997	0.000
Q70 Syndactyly	0.003	0.997	0.000
Q69 Polydactyly	0.003	0.997	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.003	0.997	0.000
T22.1 Burn of first degree of shoulder and upper limb, except wrist and hand	0.003	0.997	0.000
Q74 Other congenital malformations of limb(s)	0.003	0.997	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.000	0.997	0.003
Q12.0 Congenital cataract	0.003	0.997	0.000
Q15.0 Congenital glaucoma	0.003	0.997	0.000
Q67.6 Pectus excavatum	0.003	0.997	0.000
Q54.9 Hypospadias, unspecified	0.003	0.997	0.000
T22.0 Burn of unspecified degree of shoulder and upper limb, except wrist and hand	0.003	0.997	0.000
Q04 Other congenital malformations of brain	0.003	0.997	0.000
H65.3 Chronic mucoid otitis media	0.000	0.997	0.003
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.000	0.997	0.003
Q21.1 Atrial septal defect	0.003	0.997	0.000
Q54.0 Hypospadias, balanic	0.003	0.997	0.000
Q79.6 Ehlers-Danlos syndrome	0.003	0.997	0.000
Q34 Other congenital malformations of respiratory system	0.003	0.997	0.000
Q33 Congenital malformations of lung	0.003	0.997	0.000
Q32 Congenital malformations of trachea and bronchus	0.003	0.997	0.000
Q31 Congenital malformations of larynx	0.003	0.997	0.000
Q14.1 Congenital malformation of retina	0.003	0.997	0.000
Q06 Other congenital malformations of spinal cord	0.003	0.997	0.000
Q03 Congenital hydrocephalus	0.003	0.997	0.000
Q01 Encephalocele	0.003	0.997	0.000
Q00 Anencephaly and similar malformations	0.003	0.997	0.000
Q02 Microcephaly	0.003	0.997	0.000
Q80-Q89 Other congenital malformations	0.003	0.997	0.000
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.003	0.997	0.000
T21.7 Corrosion of third degree of trunk	0.003	0.997	0.000
T21.6 Corrosion of second degree of trunk	0.003	0.997	0.000
T21.5 Corrosion of first degree of trunk	0.003	0.997	0.000
T21.4 Corrosion of unspecified degree of trunk	0.003	0.997	0.000
T21.1 Burn of first degree of trunk	0.003	0.997	0.000
Q12.9 Congenital lens malformation, unspecified	0.003	0.997	0.000
Q12.8 Other congenital lens malformations	0.003	0.997	0.000
Q12.4 Spherophakia	0.003	0.997	0.000
Q12.3 Congenital aphakia	0.003	0.997	0.000
Q12.2 Coloboma of lens	0.003	0.997	0.000
Q12.1 Congenital displaced lens	0.003	0.997	0.000
Q15.9 Congenital malformation of eye, unspecified	0.003	0.997	0.000
Q15.8 Other specified congenital malformations of eye	0.003	0.997	0.000
S06.3 Focal brain injury	0.003	0.997	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.003	0.997	0.000
Q30.3 Congenital perforated nasal septum	0.003	0.997	0.000
Q52.4 Other congenital malformations of vagina	0.003	0.997	0.000
Q54.1 Hypospadias, penile	0.003	0.997	0.000
Q05.9 Spina bifida, unspecified	0.003	0.997	0.000
Q67.8 Other congenital deformities of chest	0.003	0.997	0.000
Q67.7 Pectus carinatum	0.003	0.997	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.003	0.997	0.000
Q67.3 Plagiocephaly	0.003	0.997	0.000
Q67.2 Dolichocephaly	0.003	0.997	0.000
Q67.1 Compression facies	0.003	0.997	0.000
Q67.0 Facial asymmetry	0.003	0.997	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.003	0.997	0.000
Q14.9 Congenital malformation of posterior segment of eye, unspecified	0.003	0.997	0.000
Q14.8 Other congenital malformations of posterior segment of eye	0.003	0.997	0.000
Q14.3 Congenital malformation of choroid	0.003	0.997	0.000
Q14.2 Congenital malformation of optic disk	0.003	0.997	0.000
Q14.0 Congenital malformation of vitreous humour	0.003	0.997	0.000
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.003	0.997	0.000
T25 Burn and corrosion of ankle and foot	0.003	0.997	0.000
Q37 Cleft palate with cleft lip	0.002	0.997	0.000
Q36 Cleft lip	0.002	0.997	0.000
Q35 Cleft palate	0.002	0.997	0.000
Q60-Q64 Congenital malformations of the urinary system	0.003	0.997	0.000
Q05.4 Unspecified spina bifida with hydrocephalus	0.003	0.997	0.000
Q55.6 Other congenital malformations of penis	0.003	0.997	0.000
Q78.9 Osteochondrodysplasia, unspecified	0.002	0.997	0.000
Q78.8 Other specified osteochondrodysplasias	0.002	0.997	0.000
Q78.6 Multiple congenital exostoses	0.002	0.997	0.000
Q78.5 Metaphyseal dysplasia	0.002	0.997	0.000
Q78.4 Enchondromatosis	0.002	0.997	0.000
Q78.3 Progressive diaphyseal dysplasia	0.002	0.997	0.000
Q78.2 Osteopetrosis	0.002	0.997	0.000
Q78.1 Polyostotic fibrous dysplasia	0.002	0.997	0.000
Q43 Other congenital malformations of intestine	0.003	0.997	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.002	0.997	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.003	0.997	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.002	0.997	0.000
Q96 Turner's syndrome	0.002	0.997	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.002	0.997	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.002	0.997	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.002	0.997	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.002	0.997	0.000
Q90 Down's syndrome	0.002	0.997	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.003	0.997	0.000
T20.7 Corrosion of third degree of head and neck	0.003	0.997	0.000
T20.6 Corrosion of second degree of head and neck	0.003	0.997	0.000
T20.5 Corrosion of first degree of head and neck	0.003	0.997	0.000
T20.4 Corrosion of unspecified degree of head and neck	0.003	0.997	0.000
T20.3 Burn of third degree of head and neck	0.003	0.997	0.000
Q10.7 Congenital malformation of orbit	0.002	0.997	0.000
Q10.6 Other congenital malformations of lachrymal apparatus	0.002	0.997	0.000
Q10.5 Congenital stenosis and stricture of lachrymal duct	0.002	0.997	0.000
Q10.4 Absence and agenesis of lachrymal apparatus	0.002	0.997	0.000
Q10.3 Other congenital malformations of eyelid	0.002	0.997	0.000
Q10.2 Congenital entropion	0.002	0.997	0.000
Q10.1 Congenital ectropion	0.002	0.997	0.000
Q10.0 Congenital ptosis	0.002	0.997	0.000
Q11.3 Macrophthalmos	0.002	0.997	0.000
Q11.2 Microphthalmos	0.002	0.997	0.000
Q11.1 Other anophthalmos	0.002	0.997	0.000
Q11.0 Cystic eyeball	0.002	0.997	0.000
Q13.9 Congenital malformation of anterior segment of eye, unspecified	0.002	0.997	0.000
Q13.8 Other congenital malformations of anterior segment of eye	0.002	0.997	0.000
Q13.5 Blue sclera	0.002	0.997	0.000
Q13.4 Other congenital corneal malformations	0.002	0.997	0.000
Q13.3 Congenital corneal opacity	0.002	0.997	0.000
Q13.2 Other congenital malformations of iris	0.002	0.997	0.000
Q13.1 Absence of iris	0.002	0.997	0.000
Q13.0 Coloboma of iris	0.002	0.997	0.000
Q16.9 Congenital malformation of ear causing impairment of hearing, unspecified	0.002	0.997	0.000
Q16.5 Congenital malformation of inner ear	0.002	0.997	0.000
Q16.4 Other congenital malformations of middle ear	0.002	0.997	0.000
Q16.3 Congenital malformation of ear ossicles	0.002	0.997	0.000
Q16.2 Absence of eustachian tube	0.002	0.997	0.000
Q16.1 Congenital absence, atresia and stricture of auditory canal (external)	0.002	0.997	0.000
Q16.0 Congenital absence of (ear) auricle	0.002	0.997	0.000
Q17.9 Congenital malformation of ear, unspecified	0.002	0.997	0.000
Q17.8 Other specified congenital malformations of ear	0.002	0.997	0.000
Q17.5 Prominent ear	0.002	0.997	0.000
Q17.4 Misplaced ear	0.002	0.997	0.000
Q17.3 Other misshapen ear	0.002	0.997	0.000
Q17.2 Microtia	0.002	0.997	0.000
Q17.1 Macrotia	0.002	0.997	0.000
Q17.0 Accessory auricle	0.002	0.997	0.000
Q54.8 Other hypospadias	0.002	0.997	0.000
Q54.4 Congenital chordee	0.002	0.997	0.000
Q54.3 Hypospadias, perineal	0.002	0.997	0.000
Q54.2 Hypospadias, penoscrotal	0.002	0.997	0.000
A04 Other bacterial intestinal infections	0.000	0.997	0.003
O14.2 HELLP syndrome	0.003	0.997	0.000
T22.7 Corrosion of third degree of shoulder and upper limb, except wrist and hand	0.003	0.997	0.000
T22.6 Corrosion of second degree of shoulder and upper limb, except wrist and hand	0.003	0.997	0.000
T22.5 Corrosion of first degree of shoulder and upper limb, except wrist and hand	0.003	0.997	0.000
T22.4 Corrosion of unspecified degree of shoulder and upper limb, except wrist and hand	0.003	0.997	0.000
R03.1 Nonspecific low blood-pressure reading	0.003	0.997	0.000
Q07 Other congenital malformations of nervous system	0.002	0.997	0.000
Q40 Other congenital malformations of upper alimentary tract	0.003	0.997	0.000
N90.5 Atrophy of vulva	0.003	0.997	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.002	0.997	0.000
Q76.8 Other congenital malformations of bony thorax	0.002	0.997	0.000
Q76.7 Congenital malformation of sternum	0.002	0.997	0.000
Q76.6 Other congenital malformations of ribs	0.002	0.997	0.000
Q76.5 Cervical rib	0.002	0.997	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.002	0.997	0.000
Q76.2 Congenital spondylolisthesis	0.002	0.997	0.000
Q76.1 Klippel-Feil syndrome	0.002	0.997	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.002	0.997	0.000
Q79.5 Other congenital malformations of abdominal wall	0.002	0.997	0.000
Q79.4 Prune belly syndrome	0.002	0.997	0.000
Q79.3 Gastroschisis	0.002	0.997	0.000
Q79.2 Exomphalos	0.002	0.997	0.000
Q79.1 Other congenital malformations of diaphragm	0.002	0.997	0.000
Q79.0 Congenital diaphragmatic hernia	0.002	0.997	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.003	0.997	0.000
Q45 Other congenital malformations of digestive system	0.002	0.997	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.002	0.997	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.002	0.997	0.000
Q05.8 Sacral spina bifida without hydrocephalus	0.002	0.997	0.000
Q05.7 Lumbar spina bifida without hydrocephalus	0.002	0.997	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.002	0.997	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.002	0.997	0.000
Q05.3 Sacral spina bifida with hydrocephalus	0.002	0.997	0.000
Q05.2 Lumbar spina bifida with hydrocephalus	0.002	0.997	0.000
Q05.1 Thoracic spina bifida with hydrocephalus	0.002	0.997	0.000
Q05.0 Cervical spina bifida with hydrocephalus	0.002	0.997	0.000
T20.2 Burn of second degree of head and neck	0.002	0.997	0.000
N90 Other noninflammatory disorders of vulva and perineum	0.003	0.997	0.000
D22.6 Melanocytic naevi of upper limb, including shoulder	0.003	0.997	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.002	0.997	0.000
Q68.4 Congenital bowing of tibia and fibula	0.002	0.997	0.000
Q68.3 Congenital bowing of femur	0.002	0.997	0.000
Q68.2 Congenital deformity of knee	0.002	0.997	0.000
Q68.1 Congenital deformity of hand	0.002	0.997	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.002	0.997	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.002	0.997	0.000
Q30.9 Congenital malformation of nose, unspecified	0.002	0.997	0.000
Q30.8 Other congenital malformations of nose	0.002	0.997	0.000
Q30.2 Fissured, notched and cleft nose	0.002	0.997	0.000
Q30.1 Agenesis and underdevelopment of nose	0.002	0.997	0.000
Q30.0 Choanal atresia	0.002	0.997	0.000
Q65 Congenital deformities of hip	0.002	0.997	0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.003	0.997	0.000
Z99.2 Dependence on renal dialysis	0.003	0.997	0.000
H65 Nonsuppurative otitis media	0.000	0.997	0.003
M18 Arthrosis of first carpometacarpal joint	0.000	0.997	0.002
Q39 Congenital malformations of oesophagus	0.002	0.997	0.000
Q52.9 Congenital malformation of female genitalia, unspecified	0.002	0.998	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.002	0.998	0.000
Q52.7 Other congenital malformations of vulva	0.002	0.998	0.000
Q52.6 Congenital malformation of clitoris	0.002	0.998	0.000
Q52.3 Imperforate hymen	0.002	0.998	0.000
Q52.2 Congenital rectovaginal fistula	0.002	0.998	0.000
Q52.1 Doubling of vagina	0.002	0.998	0.000
Q52.0 Congenital absence of vagina	0.002	0.998	0.000
Q55.9 Congenital malformation of male genital organ, unspecified	0.002	0.998	0.000
Q55.8 Other specified congenital malformations of male genital organs	0.002	0.998	0.000
Q55.5 Congenital absence and aplasia of penis	0.002	0.998	0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.002	0.998	0.000
Q55.3 Atresia of vas deferens	0.002	0.998	0.000
Q55.2 Other congenital malformations of testis and scrotum	0.002	0.998	0.000
Q55.1 Hypoplasia of testis and scrotum	0.002	0.998	0.000
Q55.0 Absence and aplasia of testis	0.002	0.998	0.000
Q69.9 Polydactyly, unspecified	0.002	0.998	0.000
Q69.2 Accessory toe(s)	0.002	0.998	0.000
Q69.1 Accessory thumb(s)	0.002	0.998	0.000
Q69.0 Accessory finger(s)	0.002	0.998	0.000
Q70.9 Syndactyly, unspecified	0.002	0.998	0.000
Q70.4 Polysyndactyly	0.002	0.998	0.000
Q70.3 Webbed toes	0.002	0.998	0.000
Q70.2 Fused toes	0.002	0.998	0.000
Q70.1 Webbed fingers	0.002	0.998	0.000
Q70.0 Fused fingers	0.002	0.998	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.002	0.998	0.000
Q71.8 Other reduction defects of upper limb(s)	0.002	0.998	0.000
Q71.6 Lobster-claw hand	0.002	0.998	0.000
Q71.5 Longitudinal reduction defect of ulna	0.002	0.998	0.000
Q71.4 Longitudinal reduction defect of radius	0.002	0.998	0.000
Q71.3 Congenital absence of hand and finger(s)	0.002	0.998	0.000
Q71.2 Congenital absence of both forearm and hand	0.002	0.998	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.002	0.998	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.002	0.998	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.002	0.998	0.000
Q72.8 Other reduction defects of lower limb(s)	0.002	0.998	0.000
Q72.7 Split foot	0.002	0.998	0.000
Q72.6 Longitudinal reduction defect of fibula	0.002	0.998	0.000
Q72.5 Longitudinal reduction defect of tibia	0.002	0.998	0.000
Q72.4 Longitudinal reduction defect of femur	0.002	0.998	0.000
Q72.3 Congenital absence of foot and toe(s)	0.002	0.998	0.000
Q72.2 Congenital absence of both lower leg and foot	0.002	0.998	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.002	0.998	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.002	0.998	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.002	0.998	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.002	0.998	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.002	0.998	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.002	0.998	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.002	0.998	0.000
Q75.5 Oculomandibular dysostosis	0.002	0.998	0.000
Q75.4 Mandibulofacial dysostosis	0.002	0.998	0.000
Q75.3 Macrocephaly	0.002	0.998	0.000
Q75.2 Hypertelorism	0.002	0.998	0.000
Q75.1 Craniofacial dysostosis	0.002	0.998	0.000
Q75.0 Craniosynostosis	0.002	0.998	0.000
Q76.0 Spina bifida occulta	0.002	0.998	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.002	0.998	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.002	0.998	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.002	0.998	0.000
Q77.6 Chondroectodermal dysplasia	0.002	0.998	0.000
Q77.5 Diastrophic dysplasia	0.002	0.998	0.000
Q77.4 Achondroplasia	0.002	0.998	0.000
Q77.3 Chondrodysplasia punctata	0.002	0.998	0.000
Q77.2 Short rib syndrome	0.002	0.998	0.000
Q77.1 Thanatophoric short stature	0.002	0.998	0.000
Q77.0 Achondrogenesis	0.002	0.998	0.000
Q43.3 Congenital malformations of intestinal fixation	0.002	0.998	0.000
G70 Myasthenia gravis and other myoneural disorders	0.002	0.998	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.002	0.998	0.000
Q04.6 Congenital cerebral cysts	0.002	0.998	0.000
Q74.9 Unspecified congenital malformation of limb(s)	0.002	0.998	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.002	0.998	0.000
Q74.3 Arthrogryposis multiplex congenita	0.002	0.998	0.000
Q74.1 Congenital malformation of knee	0.002	0.998	0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.002	0.998	0.000
T25.2 Burn of second degree of ankle and foot	0.002	0.998	0.000
Q53 Undescended testicle	0.002	0.998	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.002	0.998	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.002	0.998	0.000
D75 Other diseases of blood and blood-forming organs	0.000	0.998	0.002
D75.2 Essential thrombocytosis	0.000	0.998	0.002
Q52.5 Fusion of labia	0.002	0.998	0.000
Z99.9 Dependence on unspecified enabling machine and device	0.002	0.998	0.000
Q04.9 Congenital malformation of brain, unspecified	0.002	0.998	0.000
Q04.8 Other specified congenital malformations of brain	0.002	0.998	0.000
Q04.5 Megalencephaly	0.002	0.998	0.000
Q04.4 Septo-optic dysplasia	0.002	0.998	0.000
Q04.3 Other reduction deformities of brain	0.002	0.998	0.000
Q04.2 Holoprosencephaly	0.002	0.998	0.000
Q04.1 Arhinencephaly	0.002	0.998	0.000
Q04.0 Congenital malformations of corpus callosum	0.002	0.998	0.000
Q66 Congenital deformities of feet	0.002	0.998	0.000
Q31.9 Congenital malformation of larynx, unspecified	0.002	0.998	0.000
Q31.8 Other congenital malformations of larynx	0.002	0.998	0.000
Q31.5 Congenital laryngomalacia	0.002	0.998	0.000
Q31.4 Congenital laryngeal stridor	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations