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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs13220817
log Bayes Factor = 43.0834
Chromosome 6   position 27,356,527  (GRCh37) Explore rs13220817 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E83 Disorders of mineral metabolism
0.000 0.088 0.912
E10 Insulin-dependent diabetes mellitus
0.000 0.094 0.906
E70-E90 Metabolic disorders
0.000 0.096 0.904
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.097 0.903
E10-E14 Diabetes mellitus
0.000 0.098 0.902
E88 Other metabolic disorders
0.000 0.112 0.888
E10.5 With peripheral circulatory complications
0.000 0.116 0.884
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.118 0.881
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.122 0.878
E16 Other disorders of pancreatic internal secretion
0.000 0.134 0.866
E16.2 Hypoglycaemia, unspecified
0.000 0.143 0.857
E10.4 With neurological complications
0.000 0.187 0.813
E10.9 Without complications
0.000 0.194 0.806
E10.8 With unspecified complications
0.000 0.205 0.795
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.249 0.751
E13 Other specified diabetes mellitus
0.000 0.256 0.744
E27.1 Primary adrenocortical insufficiency
0.000 0.260 0.740
E20-E35 Disorders of other endocrine glands
0.000 0.264 0.736
E10.2 With renal complications
0.000 0.265 0.735
E27 Other disorders of adrenal gland
0.000 0.266 0.734
E88.3 Tumour lysis syndrome
0.000 0.293 0.707
E10.6 With other specified complications
0.000 0.298 0.702
E10.7 With multiple complications
0.000 0.308 0.692
E40-E46 Malnutrition
0.000 0.308 0.692
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.311 0.689
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.314 0.686
E84 Cystic fibrosis
0.000 0.324 0.676
E70 Disorders of aromatic amino-acid metabolism
0.000 0.339 0.661
E13.9 Without complications
0.000 0.340 0.660
E10.3 With ophthalmic complications
0.000 0.341 0.659
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.341 0.659
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.346 0.654
E83.8 Other disorders of mineral metabolism
0.000 0.346 0.654
E83.2 Disorders of zinc metabolism
0.000 0.346 0.654
E83.0 Disorders of copper metabolism
0.000 0.346 0.654
E00-E07 Disorders of thyroid gland
0.000 0.349 0.651
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.351 0.649
E77 Disorders of glycoprotein metabolism
0.000 0.352 0.648
E76 Disorders of glycosaminoglycan metabolism
0.000 0.352 0.648
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.352 0.648
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.352 0.648
E12 Malnutrition-related diabetes mellitus
0.000 0.353 0.646
E80.4 Gilbert's syndrome
0.000 0.358 0.642
E10.0 With coma
0.000 0.365 0.635
E72 Other disorders of amino-acid metabolism
0.000 0.367 0.633
E15 Nondiabetic hypoglycaemic coma
0.000 0.368 0.632
E10.1 With ketoacidosis
0.000 0.377 0.623
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.379 0.621
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.379 0.621
E16.4 Abnormal secretion of gastrin
0.000 0.379 0.621
E16.3 Increased secretion of glucagon
0.000 0.379 0.621
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.381 0.619
E88.9 Metabolic disorder, unspecified
0.000 0.381 0.618
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.386 0.614
E88.2 Lipomatosis, not elsewhere classified
0.000 0.398 0.602
E89.0 Postprocedural hypothyroidism
0.000 0.398 0.602
E89.4 Postprocedural ovarian failure
0.000 0.401 0.599
E25 Adrenogenital disorders
0.000 0.410 0.590
E88.8 Other specified metabolic disorders
0.000 0.413 0.587
E20 Hypoparathyroidism
0.000 0.417 0.583
E65-E68 Obesity and other hyperalimentation
0.000 0.420 0.580
E73 Lactose intolerance
0.000 0.424 0.576
E14 Unspecified diabetes mellitus
0.000 0.429 0.571
E80.6 Other disorders of bilirubin metabolism
0.000 0.430 0.570
E05.9 Thyrotoxicosis, unspecified
0.000 0.442 0.558
E79 Disorders of purine and pyrimidine metabolism
0.000 0.449 0.551
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.450 0.550
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.455 0.545
E24 Cushing's syndrome
0.000 0.457 0.543
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.458 0.542
E46 Unspecified protein-energy malnutrition
0.000 0.460 0.540
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.461 0.539
E80.5 Crigler-Najjar syndrome
0.000 0.461 0.539
E80.3 Defects of catalase and peroxydase
0.000 0.461 0.539
E80.1 Porphyria cutanea tarda
0.000 0.461 0.539
E80.0 Hereditary erythropoietic porphyria
0.000 0.461 0.539
E84.9 Cystic fibrosis, unspecified
0.000 0.465 0.535
E13.8 With unspecified complications
0.000 0.467 0.533
E13.7 With multiple complications
0.000 0.467 0.533
E13.6 With other specified complications
0.000 0.467 0.533
E13.5 With peripheral circulatory complications
0.000 0.467 0.533
E13.4 With neurological complications
0.000 0.467 0.533
E13.2 With renal complications
0.000 0.467 0.533
E13.1 With ketoacidosis
0.000 0.467 0.533
E13.0 With coma
0.000 0.467 0.533
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.472 0.528
E32 Diseases of thymus
0.000 0.472 0.528
E31 Polyglandular dysfunction
0.000 0.472 0.528
E30 Disorders of puberty, not elsewhere classified
0.000 0.472 0.528
E14.3 With ophthalmic complications
0.000 0.474 0.526
E27.5 Adrenomedullary hyperfunction
0.000 0.474 0.526
E27.0 Other adrenocortical overactivity
0.000 0.474 0.526
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.479 0.521
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.482 0.517
E29 Testicular dysfunction
0.000 0.488 0.512
E65 Localised adiposity
0.000 0.497 0.503
E80.2 Other porphyria
0.000 0.498 0.502
E16.1 Other hypoglycaemia
0.000 0.503 0.497
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.504 0.496
E45 Retarded development following protein-energy malnutrition
0.000 0.504 0.496
E43 Unspecified severe protein-energy malnutrition
0.000 0.504 0.496
E42 Marasmic kwashiorkor
0.000 0.504 0.496
E41 Nutritional marasmus
0.000 0.504 0.496
E40 Kwashiorkor
0.000 0.504 0.496
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.508 0.492
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.508 0.492
E89.1 Postprocedural hypoinsulinaemia
0.000 0.508 0.492
E26 Hyperaldosteronism
0.000 0.509 0.491
E83.3 Disorders of phosphorus metabolism
0.000 0.512 0.488
E70.3 Albinism
0.000 0.513 0.487
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.514 0.486
E84.8 Cystic fibrosis with other manifestations
0.000 0.515 0.485
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.515 0.485
E74 Other disorders of carbohydrate metabolism
0.000 0.515 0.484
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.526 0.474
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.526 0.474
E70.2 Disorders of tyrosine metabolism
0.000 0.526 0.474
E70.1 Other hyperphenylalaninaemias
0.000 0.526 0.474
E70.0 Classical phenylketonuria
0.000 0.526 0.474
E20.9 Hypoparathyroidism, unspecified
0.000 0.527 0.473
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.533 0.467
E00 Congenital iodine-deficiency syndrome
0.000 0.533 0.467
E06 Thyroiditis
0.000 0.534 0.466
E71.3 Disorders of fatty-acid metabolism
0.000 0.535 0.464
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.535 0.464
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.535 0.464
E71.0 Maple-syrup-urine disease
0.000 0.535 0.464
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.535 0.464
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.535 0.464
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.535 0.464
E76.2 Other mucopolysaccharidoses
0.000 0.535 0.464
E76.1 Mucopolysaccharidosis, type II
0.000 0.535 0.464
E76.0 Mucopolysaccharidosis, type I
0.000 0.535 0.464
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.535 0.464
E77.8 Other disorders of glycoprotein metabolism
0.000 0.535 0.464
E77.1 Defects in glycoprotein degradation
0.000 0.535 0.464
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.535 0.464
E05.8 Other thyrotoxicosis
0.000 0.536 0.464
E12.9 Without complications
0.000 0.536 0.463
E12.8 With unspecified complications
0.000 0.536 0.463
E12.7 With multiple complications
0.000 0.536 0.463
E12.6 With other specified complications
0.000 0.536 0.463
E12.5 With peripheral circulatory complications
0.000 0.536 0.463
E12.4 With neurological complications
0.000 0.536 0.463
E12.3 With ophthalmic complications
0.000 0.536 0.463
E12.2 With renal complications
0.000 0.536 0.463
E12.1 With ketoacidosis
0.000 0.536 0.463
E12.0 With coma
0.000 0.536 0.463
E78.4 Other hyperlipidaemia
0.000 0.541 0.459
E13.3 With ophthalmic complications
0.000 0.543 0.457
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.545 0.455
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.546 0.454
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.546 0.454
E72.5 Disorders of glycine metabolism
0.000 0.546 0.454
E72.4 Disorders of ornithine metabolism
0.000 0.546 0.454
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.546 0.454
E72.2 Disorders of urea cycle metabolism
0.000 0.546 0.454
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.546 0.454
E78.6 Lipoprotein deficiency
0.000 0.548 0.452
E27.2 Addisonian crisis
0.000 0.549 0.451
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.550 0.450
E24.2 Drug-induced Cushing's syndrome
0.000 0.551 0.449
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.552 0.448
E05.5 Thyroid crisis or storm
0.000 0.556 0.444
E05.4 Thyrotoxicosis factitia
0.000 0.556 0.444
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.556 0.444
E75.6 Lipid storage disorder, unspecified
0.000 0.559 0.440
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.559 0.440
E75.3 Sphingolipidosis, unspecified
0.000 0.559 0.440
E75.1 Other gangliosidosis
0.000 0.559 0.440
E75.0 GM2 gangliosidosis
0.000 0.559 0.440
E72.0 Disorders of amino-acid transport
0.000 0.560 0.439
E14.5 With peripheral circulatory complications
0.000 0.568 0.432
E75.2 Other sphingolipidosis
0.000 0.573 0.426
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.576 0.424
E25.9 Adrenogenital disorder, unspecified
0.000 0.577 0.423
E25.8 Other adrenogenital disorders
0.000 0.577 0.423
E75.5 Other lipid storage disorders
0.000 0.578 0.422
E14.2 Withrenal complications
0.000 0.578 0.422
E85 Amyloidosis
0.000 0.581 0.419
E20.8 Other hypoparathyroidism
0.000 0.582 0.418
E20.1 Pseudohypoparathyroidism
0.000 0.582 0.418
E20.0 Idiopathic hypoparathyroidism
0.000 0.582 0.418
E67 Other hyperalimentation
0.000 0.584 0.416
E68 Sequelae of hyperalimentation
0.000 0.584 0.416
E34 Other endocrine disorders
0.000 0.584 0.416
E83.5 Disorders of calcium metabolism
0.000 0.586 0.414
E73.8 Other lactose intolerance
0.000 0.587 0.413
E73.1 Secondary lactase deficiency
0.000 0.587 0.413
E73.0 Congenital lactase deficiency
0.000 0.587 0.413
E03 Other hypothyroidism
0.000 0.589 0.411
E14.7 With multiple complications
0.000 0.590 0.410
E14.0 With coma
0.000 0.590 0.410
E24.8 Other Cushing's syndrome
0.000 0.591 0.408
E24.0 Pituitary-dependent Cushing's disease
0.000 0.598 0.401
E89.5 Postprocedural testicular hypofunction
0.000 0.599 0.400
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.605 0.395
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.605 0.395
E79.1 Lesch-Nyhan syndrome
0.000 0.605 0.395
E78.3 Hyperchylomicronaemia
0.000 0.605 0.395
E14.6 With other specified complications
0.000 0.606 0.394
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.610 0.389
E24.3 Ectopic ACTH syndrome
0.000 0.610 0.389
E24.1 Nelson's syndrome
0.000 0.610 0.389
E14.1 With ketoacidosis
0.000 0.612 0.388
E14.4 With neurological complications
0.000 0.615 0.385
E30.9 Disorder of puberty, unspecified
0.000 0.621 0.378
E30.8 Other disorders of puberty
0.000 0.621 0.378
E30.1 Precocious puberty
0.000 0.621 0.378
E30.0 Delayed puberty
0.000 0.621 0.378
E31.9 Polyglandular dysfunction, unspecified
0.000 0.621 0.378
E31.8 Other polyglandular dysfunction
0.000 0.621 0.378
E31.1 Polyglandular hyperfunction
0.000 0.621 0.378
E31.0 Autoimmune polyglandular failure
0.000 0.621 0.378
E32.9 Disease of thymus, unspecified
0.000 0.621 0.378
E32.8 Other diseases of thymus
0.000 0.621 0.378
E32.1 Abscess of thymus
0.000 0.621 0.378
E32.0 Persistent hyperplasia of thymus
0.000 0.621 0.378
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.621 0.378
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.621 0.378
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.621 0.378
E03.8 Other specified hypothyroidism
0.000 0.630 0.370
E29.9 Testicular dysfunction, unspecified
0.000 0.633 0.367
E29.8 Other testicular dysfunction
0.000 0.633 0.367
E29.0 Testicular hyperfunction
0.000 0.633 0.367
E83.4 Disorders of magnesium metabolism
0.000 0.633 0.367
E23 Hypofunction and other disorders of pituitary gland
0.000 0.637 0.363
E07 Other disorders of thyroid
0.000 0.638 0.362
E44.1 Mild protein-energy malnutrition
0.000 0.644 0.356
E44.0 Moderate protein-energy malnutrition
0.000 0.644 0.356
E26.8 Other hyperaldosteronism
0.000 0.648 0.352
E26.1 Secondary hyperaldosteronism
0.000 0.648 0.352
E29.1 Testicular hypofunction
0.000 0.648 0.352
E06.5 Other chronic thyroiditis
0.000 0.648 0.351
E26.0 Primary hyperaldosteronism
0.000 0.650 0.350
E78.2 Mixed hyperlipidaemia
0.000 0.651 0.349
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.652 0.347
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.652 0.347
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.652 0.347
E74.2 Disorders of galactose metabolism
0.000 0.652 0.347
E74.1 Disorders of fructose metabolism
0.000 0.652 0.347
E06.1 Subacute thyroiditis
0.000 0.653 0.347
E73.9 Lactose intolerance, unspecified
0.000 0.658 0.342
E06.3 Autoimmune thyroiditis
0.000 0.664 0.336
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.665 0.335
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.665 0.335
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.665 0.335
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.665 0.335
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.665 0.335
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.665 0.335
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.665 0.335
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.665 0.335
E06.4 Drug-induced thyroiditis
0.000 0.666 0.334
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.666 0.334
E06.0 Acute thyroiditis
0.000 0.666 0.334
E28 Ovarian dysfunction
0.000 0.672 0.327
E85.8 Other amyloidosis
0.000 0.677 0.322
E89.2 Postprocedural hypoparathyroidism
0.000 0.681 0.319
E26.9 Hyperaldosteronism, unspecified
0.000 0.682 0.318
E78.8 Other disorders of lipoprotein metabolism
0.000 0.682 0.318
E78.1 Pure hyperglyceridaemia
0.000 0.682 0.318
E14.8 With unspecified complications
0.000 0.683 0.316
E34.9 Endocrine disorder, unspecified
0.000 0.688 0.312
E27.9 Disorder of adrenal gland, unspecified
0.001 0.694 0.306
E89.3 Postprocedural hypopituitarism
0.000 0.697 0.302
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.699 0.300
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.699 0.300
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.699 0.300
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.001 0.701 0.298
E67.8 Other specified hyperalimentation
0.000 0.702 0.298
E67.3 Hypervitaminosis D
0.000 0.702 0.298
E67.2 Megavitamin-B6 syndrome
0.000 0.702 0.298
E67.1 Hypercarotenaemia
0.000 0.702 0.298
E67.0 Hypervitaminosis A
0.000 0.702 0.298
E34.5 Androgen resistance syndrome
0.000 0.702 0.298
E34.4 Constitutional tall stature
0.000 0.702 0.298
E34.3 Short stature, not elsewhere classified
0.000 0.702 0.298
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.702 0.298
E34.1 Other hypersecretion of intestinal hormones
0.000 0.702 0.298
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.705 0.295
E03.5 Myxoedema coma
0.000 0.705 0.295
E03.4 Atrophy of thyroid (acquired)
0.000 0.705 0.295
E03.3 Postinfectious hypothyroidism
0.000 0.705 0.295
E06.9 Thyroiditis, unspecified
0.000 0.706 0.294
E74.0 Glycogen storage disease
0.001 0.709 0.290
E23.2 Diabetes insipidus
0.000 0.711 0.289
E03.1 Congenital hypothyroidism without goitre
0.000 0.712 0.288
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.720 0.280
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.727 0.272
E27.8 Other specified disorders of adrenal gland
0.001 0.729 0.270
E24.9 Cushing's syndrome, unspecified
0.000 0.736 0.264
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.739 0.260
E23.1 Drug-induced hypopituitarism
0.000 0.739 0.260
E07.1 Dyshormogenetic goitre
0.000 0.740 0.259
E07.0 Hypersecretion of calcitonin
0.000 0.740 0.259
E85.9 Amyloidosis, unspecified
0.000 0.747 0.252
E34.8 Other specified endocrine disorders
0.000 0.749 0.251
E85.3 Secondary systemic amyloidosis
0.001 0.757 0.242
E23.7 Disorder of pituitary gland, unspecified
0.000 0.760 0.240
E23.6 Other disorders of pituitary gland
0.000 0.761 0.239
E28.9 Ovarian dysfunction, unspecified
0.000 0.765 0.235
E28.8 Other ovarian dysfunction
0.000 0.765 0.235
E28.1 Androgen excess
0.000 0.765 0.235
E28.0 Oestrogen excess
0.000 0.765 0.235
E07.9 Disorder of thyroid, unspecified
0.000 0.767 0.233
K90 Intestinal malabsorption
0.000 0.768 0.232
E34.0 Carcinoid syndrome
0.000 0.771 0.229
E85.4 Organ-limited amyloidosis
0.001 0.784 0.215
E50-E64 Other nutritional deficiencies
0.000 0.788 0.212
E22 Hyperfunction of pituitary gland
0.000 0.801 0.199
E07.8 Other specified disorders of thyroid
0.000 0.802 0.197
E11 Non-insulin-dependent diabetes mellitus
0.000 0.804 0.196
E04 Other non-toxic goitre
0.000 0.807 0.193
E28.2 Polycystic ovarian syndrome
0.000 0.822 0.178
K90.8 Other intestinal malabsorption
0.000 0.823 0.177
K90.3 Pancreatic steatorrhoea
0.000 0.833 0.167
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.833 0.167
K90.1 Tropical sprue
0.000 0.833 0.167
E11.2 With renal complications
0.000 0.835 0.165
E11.1 With ketoacidosis
0.000 0.845 0.155
E04.0 Non-toxic diffuse goitre
0.000 0.845 0.155
E11.6 With other specified complications
0.000 0.847 0.153
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.848 0.152
E63 Other nutritional deficiencies
0.000 0.848 0.152
E50 Vitamin A deficiency
0.000 0.848 0.152
E60 Dietary zinc deficiency
0.000 0.848 0.152
E59 Dietary selenium deficiency
0.000 0.848 0.152
E52 Niacin deficiency [pellagra]
0.000 0.848 0.152
E51 Thiamine deficiency
0.000 0.853 0.147
E28.3 Primary ovarian failure
0.001 0.853 0.146
E58 Dietary calcium deficiency
0.000 0.854 0.146
E11.8 With unspecified complications
0.000 0.855 0.145
E56 Other vitamin deficiencies
0.000 0.855 0.145
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.855 0.145
E22.8 Other hyperfunction of pituitary gland
0.000 0.857 0.143
E11.7 With multiple complications
0.000 0.859 0.141
E04.8 Other specified non-toxic goitre
0.000 0.861 0.139
E53 Deficiency of other B group vitamins
0.000 0.867 0.133
E22.9 Hyperfunction of pituitary gland, unspecified
0.001 0.871 0.128
E11.0 With coma
0.000 0.877 0.123
E54 Ascorbic acid deficiency
0.000 0.879 0.121
E55 Vitamin D deficiency
0.000 0.879 0.121
E04.9 Non-toxic goitre, unspecified
0.000 0.879 0.121
E50.9 Vitamin A deficiency, unspecified
0.000 0.890 0.109
E50.8 Other manifestations of vitamin A deficiency
0.000 0.890 0.109
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.890 0.109
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.890 0.109
E50.5 Vitamin A deficiency with night blindness
0.000 0.890 0.109
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.890 0.109
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.890 0.109
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.890 0.109
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.890 0.109
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.890 0.109
E63.9 Nutritional deficiency, unspecified
0.000 0.890 0.109
E63.8 Other specified nutritional deficiencies
0.000 0.890 0.109
E63.1 Imbalance of constituents of food intake
0.000 0.890 0.109
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.890 0.109
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.890 0.109
E64.8 Sequelae of other nutritional deficiencies
0.000 0.890 0.109
E64.3 Sequelae of rickets
0.000 0.890 0.109
E64.2 Sequelae of vitamin C deficiency
0.000 0.890 0.109
E64.1 Sequelae of vitamin A deficiency
0.000 0.890 0.109
E64.0 Sequelae of protein-energy malnutrition
0.000 0.890 0.109
E11.5 With peripheral circulatory complications
0.000 0.891 0.109
E23.0 Hypopituitarism
0.000 0.893 0.107
E11.4 With neurological complications
0.000 0.893 0.107
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.893 0.106
E51.9 Thiamine deficiency, unspecified
0.000 0.894 0.105
E51.8 Other manifestations of thiamine deficiency
0.000 0.894 0.105
E51.1 Beriberi
0.000 0.894 0.105
E53.9 Vitamin B deficiency, unspecified
0.000 0.895 0.105
E22.1 Hyperprolactinaemia
0.001 0.895 0.105
E56.9 Vitamin deficiency, unspecified
0.000 0.896 0.104
E56.8 Deficiency of other vitamins
0.000 0.896 0.104
E56.0 Deficiency of vitamin E
0.000 0.896 0.104
E51.2 Wernicke's encephalopathy
0.000 0.899 0.100
E14.9 Without complications
0.000 0.900 0.100
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.903 0.097
E56.1 Deficiency of vitamin K
0.000 0.903 0.097
E53.1 Pyridoxine deficiency
0.000 0.904 0.095
E53.0 Riboflavin deficiency
0.000 0.904 0.095
E61 Deficiency of other nutrient elements
0.000 0.909 0.091
E66 Obesity
0.000 0.912 0.088
E22.0 Acromegaly and pituitary gigantism
0.001 0.912 0.088
E55.0 Rickets, active
0.000 0.913 0.087
K90.9 Intestinal malabsorption, unspecified
0.000 0.914 0.086
E04.2 Non-toxic multinodular goitre
0.000 0.925 0.075
E86 Volume depletion
0.000 0.928 0.072
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.929 0.071
E21.4 Other specified disorders of parathyroid gland
0.000 0.933 0.067
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.934 0.066
E21.2 Other hyperparathyroidism
0.000 0.934 0.066
E61.9 Deficiency of nutrient element, unspecified
0.000 0.934 0.065
E61.8 Deficiency of other specified nutrient elements
0.000 0.934 0.065
E61.7 Deficiency of multiple nutrient elements
0.000 0.934 0.065
E61.6 Vanadium deficiency
0.000 0.934 0.065
E61.5 Molybdenum deficiency
0.000 0.934 0.065
E61.4 Chromium deficiency
0.000 0.934 0.065
E61.3 Manganese deficiency
0.000 0.934 0.065
E61.0 Copper deficiency
0.000 0.934 0.065
E66.1 Drug-induced obesity
0.000 0.936 0.064
E61.2 Magnesium deficiency
0.000 0.942 0.057
E55.9 Vitamin D deficiency, unspecified
0.000 0.944 0.055
E53.8 Deficiency of other specified B group vitamins
0.000 0.944 0.055
E66.0 Obesity due to excess calories
0.000 0.948 0.051
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.952 0.048
E11.3 With ophthalmic complications
0.000 0.954 0.046
E04.1 Non-toxic single thyroid nodule
0.000 0.969 0.031
E21.3 Hyperparathyroidism, unspecified
0.000 0.974 0.025
E61.1 Iron deficiency
0.001 0.975 0.025
K51.2 Ulcerative (chronic) proctitis
0.024 0.976 0.000
E78.5 Hyperlipidaemia, unspecified
0.000 0.980 0.020
G35 Multiple sclerosis
0.000 0.982 0.018
G30.9 Alzheimer's disease, unspecified
0.000 0.982 0.018
E21.0 Primary hyperparathyroidism
0.000 0.983 0.016
R31 Unspecified haematuria
0.016 0.984 0.000
E11.9 Without complications
0.000 0.985 0.015
G30 Alzheimer's disease
0.000 0.985 0.015
K90-K93 Other diseases of the digestive system
0.000 0.986 0.014
H11.4 Other conjunctival vascular disorders and cysts
0.013 0.987 0.000
H11 Other disorders of conjunctiva
0.013 0.987 0.000
H11.9 Disorder of conjunctiva, unspecified
0.013 0.987 0.000
H11.8 Other specified disorders of conjunctiva
0.012 0.988 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.012 0.988 0.000
G30.0 Alzheimer's disease with early onset
0.000 0.988 0.012
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.000 0.988 0.012
G31.8 Other specified degenerative diseases of nervous system
0.000 0.988 0.011
G30-G32 Other degenerative diseases of the nervous system
0.000 0.989 0.011
H11.0 Pterygium
0.011 0.989 0.000
G30.1 Alzheimer's disease with late onset
0.000 0.989 0.011
G31.0 Circumscribed brain atrophy
0.000 0.989 0.011
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.990 0.010
E03.9 Hypothyroidism, unspecified
0.000 0.990 0.010
G30.8 Other Alzheimer's disease
0.000 0.990 0.010
H11.1 Conjunctival degenerations and deposits
0.010 0.990 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.000 0.991 0.009
H11.2 Conjunctival scars
0.009 0.991 0.000
G31.1 Senile degeneration of brain, not elsewhere classified
0.000 0.991 0.008
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.992 0.008
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.992 0.008
E66.9 Obesity, unspecified
0.000 0.992 0.008
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.992 0.007
K93.1 Megacolon in Chagas' disease
0.000 0.992 0.007
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.992 0.007
N04.9 Unspecified
0.000 0.993 0.007
E87.4 Mixed disorder of acid-base balance
0.000 0.994 0.006
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.994 0.006
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere
0.000 0.994 0.006
E87.7 Fluid overload
0.000 0.994 0.006
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.994 0.006
G31.2 Degeneration of nervous system due to alcohol
0.000 0.994 0.005
O04.9 Complete or unspecified, without complication
0.006 0.994 0.000
C71.2 Temporal lobe
0.006 0.994 0.000
E66.8 Other obesity
0.000 0.994 0.005
M25.57 Pain in joint (Ankle and foot)
0.000 0.995 0.005
H10-H13 Disorders of conjunctiva
0.005 0.995 0.000
E87.0 Hyperosmolality and hypernatraemia
0.000 0.995 0.005
M41.9 Scoliosis, unspecified
0.005 0.995 0.000
M41.97 Scoliosis, unspecified (Lumbosacral region)
0.005 0.995 0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)
0.005 0.995 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.995 0.005
N18.4 Chronic kidney disease, stage 4
0.000 0.995 0.005
M41.96 Scoliosis, unspecified (Lumbar region)
0.005 0.995 0.000
E87.5 Hyperkalaemia
0.000 0.995 0.005
I49.5 Sick sinus syndrome
0.005 0.995 0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)
0.004 0.996 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.004 0.996 0.000
M41.94 Scoliosis, unspecified (Thoracic region)
0.004 0.996 0.000
G37 Other demyelinating diseases of central nervous system
0.000 0.996 0.004
E87.3 Alkalosis
0.000 0.996 0.004
L81.9 Disorder of pigmentation, unspecified
0.000 0.996 0.004
H13 Disorders of conjunctiva in diseases classified elsewhere
0.004 0.996 0.000
H11.3 Conjunctival haemorrhage
0.004 0.996 0.000
G36 Other acute disseminated demyelination
0.000 0.996 0.004
Y83.2 Surgical operation with anastomosis, bypass or graft
0.004 0.996 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.996 0.004
C71 Malignant neoplasm of brain
0.004 0.996 0.000
K56.4 Other impaction of intestine
0.004 0.996 0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)
0.004 0.996 0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)
0.004 0.996 0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)
0.004 0.996 0.000
M41.92 Scoliosis, unspecified (Cervical region)
0.004 0.996 0.000
N04 Nephrotic syndrome
0.000 0.996 0.004
H10 Conjunctivitis
0.003 0.996 0.000
C71.9 Brain, unspecified
0.004 0.996 0.000
C71.0 Cerebrum, except lobes and ventricles
0.004 0.996 0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)
0.003 0.996 0.000
C71.3 Parietal lobe
0.003 0.997 0.000
Q65.8 Other congenital deformities of hip
0.003 0.997 0.000
G37.5 Concentric sclerosis [Balo]
0.000 0.997 0.003
G37.4 Subacute necrotising myelitis
0.000 0.997 0.003
G37.2 Central pontine myelinolysis
0.000 0.997 0.003
G37.1 Central demyelination of corpus callosum
0.000 0.997 0.003
G37.0 Diffuse sclerosis
0.000 0.997 0.003
H13.3 Ocular pemphigoid
0.003 0.997 0.000
H10.4 Chronic conjunctivitis
0.003 0.997 0.000
Z74.0 Reduced mobility
0.000 0.997 0.003
H10.3 Acute conjunctivitis, unspecified
0.003 0.997 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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