TreeWAS – Variant ID: rs13220896

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
C44 Other malignant neoplasms of skin	1.000	0.000	0.000
L40.9 Psoriasis, unspecified	0.998	0.002	0.000
S60-S69 Injuries to the wrist and hand	0.998	0.002	0.000
C44.3 Skin of other and unspecified parts of face	0.998	0.002	0.000
L40 Psoriasis	0.998	0.002	0.000
Chapter XX External causes of morbidity and mortality	0.998	0.002	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.998	0.002	0.000
L40-L45 Papulosquamous disorders	0.998	0.002	0.000
E83.1 Disorders of iron metabolism	0.996	0.004	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.994	0.005	0.001
C43-C44 Melanoma and other malignant neoplasms of skin	0.994	0.006	0.000
E70-E90 Metabolic disorders	0.993	0.007	0.000
E83 Disorders of mineral metabolism	0.993	0.007	0.000
S61 Open wound of wrist and hand	0.992	0.008	0.000
Chapter II Neoplasms	0.991	0.009	0.000
Chapter V Mental and behavioural disorders	0.991	0.009	0.000
C44.1 Skin of eyelid, including canthus	0.984	0.016	0.000
S00-S09 Injuries to the head	0.983	0.017	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.982	0.018	0.000
J45.9 Asthma, unspecified	0.000	0.021	0.979
S61.0 Open wound of finger(s) without damage to nail	0.972	0.028	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.966	0.034	0.000
S02 Fracture of skull and facial bones	0.962	0.038	0.000
C44.4 Skin of scalp and neck	0.958	0.042	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.957	0.043	0.000
S06 Intracranial injury	0.954	0.046	0.000
E20-E35 Disorders of other endocrine glands	0.954	0.046	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.954	0.046	0.000
F30-F39 Mood [affective] disorders	0.946	0.054	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.946	0.054	0.000
S61.8 Open wound of other parts of wrist and hand	0.935	0.065	0.000
W20-W49 Exposure to inanimate mechanical forces	0.932	0.068	0.000
Chapter VI Diseases of the nervous system	0.928	0.072	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.922	0.078	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.919	0.081	0.000
G35 Multiple sclerosis	0.911	0.089	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.901	0.099	0.000
T84.1 Mechanical complication of internal fixation device of bones of limb	0.900	0.100	0.000
F31 Bipolar affective disorder	0.900	0.100	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.898	0.102	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.890	0.110	0.000
C44.2 Skin of ear and external auricular canal	0.886	0.114	0.000
S70-S79 Injuries to the hip and thigh	0.886	0.114	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.883	0.116	0.000
S02.4 Fracture of malar and maxillary bones	0.878	0.122	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.876	0.124	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.873	0.127	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.870	0.130	0.000
L57 Skin changes due to chronic exposure to nonionising radiation	0.867	0.133	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.867	0.133	0.000
S02.8 Fractures of other skull and facial bones	0.866	0.134	0.000
Y57 Other and unspecified drugs and medicaments	0.863	0.137	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.862	0.138	0.000
D41.4 Bladder	0.856	0.144	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.854	0.146	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.853	0.147	0.000
E21.3 Hyperparathyroidism, unspecified	0.849	0.151	0.000
E23 Hypofunction and other disorders of pituitary gland	0.844	0.156	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.843	0.157	0.000
S90-S99 Injuries to the ankle and foot	0.842	0.158	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.841	0.159	0.000
S64 Injury of nerves at wrist and hand level	0.840	0.160	0.000
W22 Striking against or struck by other objects	0.838	0.162	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.835	0.165	0.000
S10-S19 Injuries to the neck	0.834	0.166	0.000
Y52 Agents primarily affecting the cardiovascular system	0.833	0.167	0.000
T66-T78 Other and unspecified effects of external causes	0.830	0.170	0.000
T86 Failure and rejection of transplanted organs and tissues	0.827	0.173	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.823	0.177	0.000
S06.5 Traumatic subdural haemorrhage	0.822	0.178	0.000
E78.5 Hyperlipidaemia, unspecified	0.821	0.179	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.820	0.180	0.000
V40-V49 Car occupant injured in transport accident	0.818	0.182	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.817	0.183	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.817	0.183	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.813	0.187	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.809	0.191	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.809	0.191	0.000
L57.0 Actinic keratosis	0.808	0.192	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.808	0.192	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.807	0.193	0.000
Y95 Nosocomial condition	0.801	0.199	0.000
S80-S89 Injuries to the knee and lower leg	0.800	0.200	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.800	0.200	0.000
F80-F89 Disorders of psychological development	0.798	0.202	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.798	0.202	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.798	0.202	0.000
W29 Contact with other powered hand tools and household machinery	0.796	0.203	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.796	0.204	0.000
C64-C68 Malignant neoplasms of urinary tract	0.794	0.206	0.000
Y44 Agents primarily affecting blood constituents	0.791	0.209	0.000
Y57.9 Drug or medicament, unspecified	0.790	0.210	0.000
L40.8 Other psoriasis	0.787	0.212	0.000
T88.4 Failed or difficult intubation	0.787	0.213	0.000
S02.1 Fracture of base of skull	0.787	0.213	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.786	0.214	0.000
S20-S29 Injuries to the thorax	0.786	0.214	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.785	0.215	0.000
W50-W64 Exposure to animate mechanical forces	0.784	0.216	0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.782	0.218	0.000
V01-V09 Pedestrian injured in transport accident	0.782	0.218	0.000
F99-F99 Unspecified mental disorder	0.781	0.219	0.000
L40.5 Arthropathic psoriasis	0.778	0.222	0.000
Y40 Systemic antibiotics	0.778	0.222	0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.776	0.224	0.000
W22.9 Unspecified place	0.771	0.229	0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.771	0.229	0.000
S32 Fracture of lumbar spine and pelvis	0.771	0.229	0.000
X20-X29 Contact with venomous animals and plants	0.771	0.229	0.000
V10-V19 Pedal cyclist injured in transport accident	0.770	0.229	0.000
E29 Testicular dysfunction	0.765	0.235	0.000
F43 Reaction to severe stress, and adjustment disorders	0.762	0.238	0.000
C44.5 Skin of trunk	0.760	0.240	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.760	0.240	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.760	0.240	0.000
S05 Injury of eye and orbit	0.757	0.243	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.757	0.243	0.000
S06.4 Epidural haemorrhage	0.757	0.243	0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.754	0.245	0.000
Chapter XXII Codes for special purposes	0.753	0.247	0.000
S02.2 Fracture of nasal bones	0.752	0.248	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.750	0.250	0.000
C44.7 Skin of lower limb, including hip	0.750	0.250	0.000
E87.6 Hypokalaemia	0.750	0.250	0.000
T23 Burn and corrosion of wrist and hand	0.750	0.250	0.000
C44.9 Malignant neoplasm of skin, unspecified	0.748	0.252	0.000
S06.2 Diffuse brain injury	0.747	0.252	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.747	0.253	0.000
F30 Manic episode	0.746	0.254	0.000
T84.2 Mechanical complication of internal fixation device of other bones	0.743	0.257	0.000
S67 Crushing injury of wrist and hand	0.742	0.258	0.000
Q80-Q89 Other congenital malformations	0.740	0.260	0.000
S06.3 Focal brain injury	0.739	0.261	0.000
L40.0 Psoriasis vulgaris	0.739	0.261	0.000
T84.3 Mechanical complication of other bone devices, implants and grafts	0.738	0.262	0.000
T81 Complications of procedures, not elsewhere classified	0.737	0.263	0.000
S50-S59 Injuries to the elbow and forearm	0.736	0.264	0.000
Chapter VII Diseases of the eye and adnexa	0.736	0.264	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.735	0.265	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.735	0.265	0.000
C44.6 Skin of upper limb, including shoulder	0.734	0.266	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.733	0.267	0.000
S68 Traumatic amputation of wrist and hand	0.732	0.268	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.732	0.268	0.000
E40-E46 Malnutrition	0.731	0.269	0.001
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.730	0.270	0.000
S61.7 Multiple open wounds of wrist and hand	0.729	0.271	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.728	0.272	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.728	0.272	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.728	0.272	0.000
G37 Other demyelinating diseases of central nervous system	0.725	0.275	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.724	0.276	0.000
D43.0 Brain, supratentorial	0.724	0.276	0.000
G30-G32 Other degenerative diseases of the nervous system	0.723	0.277	0.000
D45 Polycythaemia vera	0.722	0.278	0.000
T78 Adverse effects, not elsewhere classified	0.721	0.279	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.719	0.281	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.718	0.281	0.000
E73 Lactose intolerance	0.718	0.282	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.717	0.283	0.000
T33-T35 Frostbite	0.717	0.283	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283	0.000
T00-T07 Injuries involving multiple body regions	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
C44.8 Overlapping lesion of skin	0.717	0.283	0.000
S82 Fracture of lower leg, including ankle	0.716	0.284	0.000
W00-W19 Falls	0.716	0.284	0.000
S69 Other and unspecified injuries of wrist and hand	0.716	0.284	0.000
S65 Injury of blood vessels at wrist and hand level	0.716	0.284	0.000
L40.4 Guttate psoriasis	0.716	0.284	0.000
L40.3 Pustulosis palmaris et plantaris	0.716	0.284	0.000
L40.2 Acrodermatitis continua	0.716	0.284	0.000
L40.1 Generalised pustular psoriasis	0.716	0.284	0.000
Y35-Y36 Legal intervention and operations of war	0.716	0.284	0.000
Y10-Y34 Event of undetermined intent	0.716	0.284	0.000
Y00-Y09 Assault	0.716	0.284	0.000
X85-X99 Assault	0.716	0.284	0.000
X30-X39 Exposure to forces of nature	0.716	0.284	0.000
X10-X19 Contact with heat and hot substances	0.716	0.284	0.000
X00-X09 Exposure to smoke, fire and flames	0.716	0.284	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.716	0.284	0.000
W75-W84 Other accidental threats to breathing	0.716	0.284	0.000
W65-W74 Accidental drowning and submersion	0.716	0.284	0.000
V98-V99 Other and unspecified transport accidents	0.716	0.284	0.000
V95-V97 Air and space transport accidents	0.716	0.284	0.000
V90-V94 Water transport accidents	0.716	0.284	0.000
V70-V79 Bus occupant injured in transport accident	0.716	0.284	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.716	0.284	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.716	0.284	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.716	0.284	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.715	0.285	0.000
L10-L14 Bullous disorders	0.715	0.285	0.000
L44 Other papulosquamous disorders	0.715	0.285	0.000
L41 Parapsoriasis	0.715	0.285	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.715	0.285	0.000
L42 Pityriasis rosea	0.715	0.285	0.000
T91 Sequelae of injuries of neck and trunk	0.715	0.285	0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.714	0.286	0.000
S90 Superficial injury of ankle and foot	0.714	0.286	0.000
F31.9 Bipolar affective disorder, unspecified	0.713	0.287	0.000
E85 Amyloidosis	0.712	0.288	0.000
E84 Cystic fibrosis	0.712	0.288	0.000
E79 Disorders of purine and pyrimidine metabolism	0.712	0.288	0.000
E77 Disorders of glycoprotein metabolism	0.712	0.288	0.000
E76 Disorders of glycosaminoglycan metabolism	0.712	0.288	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.712	0.288	0.000
E74 Other disorders of carbohydrate metabolism	0.712	0.288	0.000
E72 Other disorders of amino-acid metabolism	0.712	0.288	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.712	0.288	0.000
E70 Disorders of aromatic amino-acid metabolism	0.712	0.288	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.712	0.288	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.712	0.288	0.000
E83.8 Other disorders of mineral metabolism	0.712	0.288	0.000
E83.2 Disorders of zinc metabolism	0.712	0.288	0.000
E83.0 Disorders of copper metabolism	0.712	0.288	0.000
S64.0 Injury of ulnar nerve at wrist and hand level	0.711	0.289	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.711	0.289	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.711	0.289	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.710	0.290	0.000
F70-F79 Mental retardation	0.710	0.290	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.710	0.290	0.000
E34 Other endocrine disorders	0.708	0.292	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.708	0.292	0.000
H40-H42 Glaucoma	0.708	0.292	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.708	0.292	0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.708	0.292	0.000
X50-X57 Overexertion, travel and privation	0.707	0.293	0.000
S02.0 Fracture of vault of skull	0.706	0.294	0.000
T92 Sequelae of injuries of upper limb	0.706	0.294	0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.706	0.294	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.705	0.295	0.000
S08 Traumatic amputation of part of head	0.705	0.295	0.000
S07 Crushing injury of head	0.705	0.295	0.000
S04 Injury of cranial nerves	0.705	0.295	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.705	0.295	0.000
T86.8 Failure and rejection of other transplanted organs and tissues	0.704	0.296	0.000
T87 Complications peculiar to reattachment and amputation	0.704	0.296	0.000
S79 Other and unspecified injuries of hip and thigh	0.703	0.297	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.701	0.299	0.000
V80-V89 Other land transport accidents	0.701	0.299	0.000
W44 Foreign body entering into or through eye or natural orifice	0.700	0.300	0.000
W29.9 Unspecified place	0.700	0.300	0.000
V20-V29 Motorcycle rider injured in transport accident	0.698	0.301	0.000
S32.0 Fracture of lumbar vertebra	0.698	0.302	0.000
F33 Recurrent depressive disorder	0.697	0.303	0.000
W20 Struck by thrown, projected or falling object	0.695	0.304	0.000
F44 Dissociative [conversion] disorders	0.694	0.306	0.000
S61.1 Open wound of finger(s) with damage to nail	0.693	0.307	0.000
Y59 Other and unspecified vaccines and biological substances	0.692	0.307	0.000
Y58 Bacterial vaccines	0.692	0.307	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.692	0.307	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.692	0.307	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.692	0.307	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.692	0.307	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.692	0.307	0.000
Y48 Anaesthetics and therapeutic gases	0.692	0.307	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.692	0.307	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.692	0.307	0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.692	0.308	0.000
E26 Hyperaldosteronism	0.692	0.308	0.000
S12 Fracture of neck	0.691	0.309	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.691	0.309	0.000
S02.7 Multiple fractures involving skull and facial bones	0.689	0.310	0.000
H40 Glaucoma	0.688	0.312	0.000
E23.0 Hypopituitarism	0.687	0.313	0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.686	0.314	0.000
S66.8 Injury of other muscles and tendons at wrist and hand level	0.686	0.314	0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.686	0.314	0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.686	0.314	0.000
E23.7 Disorder of pituitary gland, unspecified	0.686	0.314	0.000
C73 Malignant neoplasm of thyroid gland	0.685	0.315	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.685	0.315	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.685	0.315	0.000
S06.9 Intracranial injury, unspecified	0.684	0.316	0.000
S06.8 Other intracranial injuries	0.684	0.316	0.000
S06.7 Intracranial injury with prolonged coma	0.684	0.316	0.000
S06.1 Traumatic cerebral oedema	0.684	0.316	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.684	0.316	0.000
E32 Diseases of thymus	0.684	0.316	0.000
E31 Polyglandular dysfunction	0.684	0.316	0.000
E30 Disorders of puberty, not elsewhere classified	0.684	0.316	0.000
E25 Adrenogenital disorders	0.684	0.316	0.000
E24 Cushing's syndrome	0.684	0.316	0.000
E20 Hypoparathyroidism	0.684	0.316	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.684	0.316	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.684	0.316	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.684	0.316	0.000
F40 Phobic anxiety disorders	0.680	0.320	0.000
S70 Superficial injury of hip and thigh	0.679	0.321	0.000
F38 Other mood [affective] disorders	0.678	0.322	0.000
F34 Persistent mood [affective] disorders	0.678	0.322	0.000
F39 Unspecified mood [affective] disorder	0.678	0.322	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.677	0.323	0.000
E88 Other metabolic disorders	0.675	0.325	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.675	0.325	0.000
H40.1 Primary open-angle glaucoma	0.675	0.325	0.000
V49 Car occupant injured in other and unspecified transport accidents	0.675	0.325	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.675	0.325	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.674	0.326	0.000
F32 Depressive episode	0.674	0.326	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.674	0.326	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.673	0.326	0.000
E28 Ovarian dysfunction	0.673	0.327	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.673	0.327	0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.673	0.327	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.673	0.327	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.672	0.327	0.000
S64.1 Injury of median nerve at wrist and hand level	0.671	0.328	0.000
F60-F69 Disorders of adult personality and behaviour	0.671	0.329	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.670	0.330	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.670	0.330	0.000
S02.3 Fracture of orbital floor	0.669	0.331	0.000
S40-S49 Injuries to the shoulder and upper arm	0.669	0.331	0.000
S02.5 Fracture of tooth	0.668	0.332	0.000
S06.0 Concussion	0.668	0.332	0.000
W49 Exposure to other and unspecified inanimate mechanical forces	0.668	0.332	0.000
W46 Contact with hypodermic needle	0.668	0.332	0.000
W45 Foreign body or object entering through skin	0.668	0.332	0.000
W43 Exposure to vibration	0.668	0.332	0.000
W42 Exposure to noise	0.668	0.332	0.000
W41 Exposure to high-pressure jet	0.668	0.332	0.000
W40 Explosion of other materials	0.668	0.332	0.000
W39 Discharge of firework	0.668	0.332	0.000
W38 Explosion and rupture of other specified pressurised devices	0.668	0.332	0.000
W37 Explosion and rupture of pressurised tyre, pipe or hose	0.668	0.332	0.000
W36 Explosion and rupture of gas cylinder	0.668	0.332	0.000
W35 Explosion and rupture of boiler	0.668	0.332	0.000
W34 Discharge from other and unspecified firearms	0.668	0.332	0.000
W33 Rifle, shotgun and larger firearm discharge	0.668	0.332	0.000
W32 Handgun discharge	0.668	0.332	0.000
W31 Contact with other and unspecified machinery	0.668	0.332	0.000
W30 Contact with agricultural machinery	0.668	0.332	0.000
W28 Contact with powered lawn mower	0.668	0.332	0.000
W27 Contact with nonpowered hand tool	0.668	0.332	0.000
W26 Contact with knife, sword or dagger	0.668	0.332	0.000
W24 Contact with lifting and transmission devices, not elsewhere classified	0.668	0.332	0.000
W23 Caught, crushed, jammed or pinched in or between objects	0.668	0.332	0.000
F06.7 Mild cognitive disorder	0.667	0.333	0.000
E87.7 Fluid overload	0.667	0.333	0.000
F45 Somatoform disorders	0.666	0.334	0.000
Y44.2 Anticoagulants	0.665	0.334	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.665	0.335	0.000
E23.6 Other disorders of pituitary gland	0.665	0.335	0.000
L50-L54 Urticaria and erythema	0.663	0.337	0.000
T20 Burn and corrosion of head and neck	0.662	0.337	0.000
G70-G73 Diseases of myoneural junction and muscle	0.662	0.338	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.662	0.338	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.662	0.338	0.000
S02.10 Fracture of base of skull (closed)	0.661	0.339	0.000
L59 Other disorders of skin and subcutaneous tissue related to radiation	0.661	0.339	0.000
L58 Radiodermatitis	0.661	0.339	0.000
L56 Other acute skin changes due to ultraviolet radiation	0.661	0.339	0.000
L55 Sunburn	0.661	0.339	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.660	0.340	0.000
S72 Fracture of femur	0.660	0.340	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.660	0.340	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.660	0.340	0.000
F52 Sexual dysfunction, not caused by organic disorder or disease	0.660	0.340	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.659	0.341	0.000
G36 Other acute disseminated demyelination	0.659	0.341	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.658	0.342	0.000
X60-X84 Intentional self-harm	0.656	0.344	0.000
O85-O92 Complications predominantly related to the puerperium	0.656	0.344	0.000
F20 Schizophrenia	0.656	0.344	0.000
E10.9 Without complications	0.000	0.344	0.656
T78.4 Allergy, unspecified	0.656	0.344	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.656	0.344	0.000
D43.2 Brain, unspecified	0.655	0.345	0.000
T83.3 Mechanical complication of intra-uterine contraceptive device	0.655	0.345	0.000
J45 Asthma	0.000	0.345	0.655
D46 Myelodysplastic syndromes	0.655	0.345	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.654	0.346	0.001
C44.0 Skin of lip	0.653	0.347	0.000
Q50-Q56 Congenital malformations of genital organs	0.651	0.349	0.000
Q00-Q07 Congenital malformations of the nervous system	0.648	0.352	0.000
W21 Striking against or struck by sports equipment	0.646	0.354	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.646	0.354	0.000
E21.4 Other specified disorders of parathyroid gland	0.646	0.354	0.000
E21.2 Other hyperparathyroidism	0.646	0.354	0.000
F31.8 Other bipolar affective disorders	0.645	0.354	0.000
F31.7 Bipolar affective disorder, currently in remission	0.645	0.354	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.645	0.354	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.645	0.354	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.645	0.354	0.000
S02.6 Fracture of mandible	0.645	0.355	0.000
S32.00 Fracture of lumbar vertebra (closed)	0.645	0.355	0.000
Y40.9 Systemic antibiotic, unspecified	0.645	0.355	0.000
E21.0 Primary hyperparathyroidism	0.645	0.355	0.000
D37.5 Rectum	0.644	0.356	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.644	0.356	0.000
Q35-Q37 Cleft lip and cleft palate	0.644	0.356	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.644	0.356	0.000
F25 Schizoaffective disorders	0.642	0.358	0.000
Q23 Congenital malformations of aortic and mitral valves	0.642	0.358	0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.642	0.358	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.641	0.359	0.000
S99 Other and unspecified injuries of ankle and foot	0.639	0.360	0.000
O00-O08 Pregnancy with abortive outcome	0.639	0.361	0.000
S10 Superficial injury of neck	0.639	0.361	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.639	0.361	0.000
D41.9 Urinary organ, unspecified	0.638	0.362	0.000
D41.7 Other urinary organs	0.638	0.362	0.000
D41.3 Urethra	0.638	0.362	0.000
D41.2 Ureter	0.638	0.362	0.000
D41.1 Renal pelvis	0.638	0.362	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.637	0.363	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.636	0.364	0.000
S78 Traumatic amputation of hip and thigh	0.635	0.365	0.000
S77 Crushing injury of hip and thigh	0.635	0.365	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.635	0.365	0.000
S75 Injury of blood vessels at hip and thigh level	0.635	0.365	0.000
S74 Injury of nerves at hip and thigh level	0.635	0.365	0.000
S71 Open wound of hip and thigh	0.635	0.365	0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.634	0.366	0.000
Y91 Evidence of alcohol involvement determined by level of intoxication	0.633	0.366	0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level	0.633	0.366	0.000
Y98 Lifestyle-related condition	0.633	0.366	0.000
Y97 Environmental-pollution-related condition	0.633	0.366	0.000
Y96 Work-related condition	0.633	0.366	0.000
T86.1 Kidney transplant failure and rejection	0.633	0.367	0.000
S61.9 Open wound of wrist and hand, part unspecified	0.632	0.368	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.631	0.368	0.000
F84 Pervasive developmental disorders	0.631	0.369	0.000
E10 Insulin-dependent diabetes mellitus	0.005	0.369	0.626
F99 Mental disorder, not otherwise specified	0.630	0.370	0.000
E29.1 Testicular hypofunction	0.630	0.370	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.629	0.371	0.000
E78.4 Other hyperlipidaemia	0.629	0.371	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.629	0.371	0.000
T25 Burn and corrosion of ankle and foot	0.628	0.372	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.628	0.372	0.000
T21 Burn and corrosion of trunk	0.628	0.372	0.000
F32.2 Severe depressive episode without psychotic symptoms	0.628	0.372	0.000
Y42.7 Androgens and anabolic congeners	0.628	0.372	0.000
V01 Pedestrian injured in collision with pedal cycle	0.627	0.373	0.000
S73.0 Dislocation of hip	0.626	0.374	0.000
F48 Other neurotic disorders	0.626	0.374	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.626	0.374	0.000
H55-H59 Other disorders of eye and adnexa	0.626	0.374	0.000
T23.3 Burn of third degree of wrist and hand	0.625	0.375	0.000
F22 Persistent delusional disorders	0.625	0.375	0.000
W25 Contact with sharp glass	0.624	0.376	0.000
T88.9 Complication of surgical and medical care, unspecified	0.624	0.376	0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.624	0.376	0.000
T88.5 Other complications of anaesthesia	0.624	0.376	0.000
T88.3 Malignant hyperthermia due to anaesthesis	0.624	0.376	0.000
T88.2 Shock due to anaesthesia	0.624	0.376	0.000
T88.1 Other complications following immunisation, not elsewhere classified	0.624	0.376	0.000
T88.0 Infection following immunisation	0.624	0.376	0.000
D37.9 Digestive organ, unspecified	0.623	0.377	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.623	0.377	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.622	0.378	0.000
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.622	0.378	0.000
L57.5 Actinic granuloma	0.622	0.378	0.000
L57.4 Cutis laxa senilis	0.622	0.378	0.000
L57.3 Poikiloderma of Civatte	0.622	0.378	0.000
L57.2 Cutis rhomboidalis nuchae	0.622	0.378	0.000
L57.1 Actinic reticuloid	0.622	0.378	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.621	0.378	0.000
S37 Injury of urinary and pelvic organs	0.621	0.378	0.000
S36 Injury of intra-abdominal organs	0.621	0.378	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.621	0.378	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.621	0.378	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.621	0.378	0.000
S31 Open wound of abdomen, lower back and pelvis	0.621	0.378	0.000
S02.81 Fractures of other skull and facial bones (open)	0.621	0.379	0.000
Y57.5 X-ray contrast media	0.620	0.380	0.000
E22 Hyperfunction of pituitary gland	0.619	0.380	0.000
F02 Dementia in other diseases classified elsewhere	0.619	0.381	0.000
W55 Bitten or struck by other mammals	0.619	0.381	0.000
Y57.8 Other drugs and medicaments	0.619	0.381	0.000
Y57.7 Vitamins, not elsewhere classified	0.619	0.381	0.000
Y57.6 Other diagnostic agents	0.619	0.381	0.000
Y57.4 Pharmaceutical excipients	0.619	0.381	0.000
Y57.3 Alcohol deterrents	0.619	0.381	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.619	0.381	0.000
Y57.1 Lipotropic drugs	0.619	0.381	0.000
Y57.0 Appetite depressants [anorectics]	0.619	0.381	0.000
F43.2 Adjustment disorders	0.619	0.381	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.618	0.382	0.000
S60 Superficial injury of wrist and hand	0.616	0.384	0.000
L60-L75 Disorders of skin appendages	0.616	0.384	0.000
E87.2 Acidosis	0.616	0.384	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.615	0.385	0.000
L43 Lichen planus	0.614	0.386	0.000
T98 Sequelae of other and unspecified effects of external causes	0.612	0.388	0.000
T95 Sequelae of burns, corrosions and frostbite	0.612	0.388	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.612	0.388	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.612	0.388	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.612	0.388	0.000
E78.6 Lipoprotein deficiency	0.612	0.388	0.000
E78.3 Hyperchylomicronaemia	0.612	0.388	0.000
E78.1 Pure hyperglyceridaemia	0.612	0.388	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.612	0.388	0.000
F81 Specific developmental disorders of scholastic skills	0.612	0.388	0.000
S80 Superficial injury of lower leg	0.611	0.389	0.000
S91 Open wound of ankle and foot	0.610	0.390	0.000
G20-G26 Extrapyramidal and movement disorders	0.609	0.391	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations