TreeWAS – Variant ID: rs13230047

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
R50-R69 General symptoms and signs	0.030	0.970	0.000
R55 Syncope and collapse	0.030	0.970	0.000
R51 Headache	0.029	0.971	0.000
R20.2 Paraesthesia of skin	0.028	0.972	0.000
R63 Symptoms and signs concerning food and fluid intake	0.027	0.973	0.000
R20 Disturbances of skin sensation	0.026	0.974	0.000
R52 Pain, not elsewhere classified	0.025	0.975	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.025	0.975	0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.025	0.975	0.000
R53 Malaise and fatigue	0.025	0.975	0.000
R61 Hyperhidrosis	0.024	0.975	0.000
R60 Oedema, not elsewhere classified	0.024	0.975	0.000
R63.4 Abnormal weight loss	0.024	0.976	0.000
R54 Senility	0.024	0.976	0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.024	0.976	0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.024	0.976	0.000
R11 Nausea and vomiting	0.024	0.976	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.024	0.976	0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.023	0.977	0.000
R29.6 Tendency to fall, not elsewhere classified	0.023	0.977	0.000
R52.2 Other chronic pain	0.022	0.978	0.000
M06.9 Rheumatoid arthritis, unspecified	0.022	0.978	0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.022	0.978	0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.022	0.978	0.000
R62 Lack of expected normal physiological development	0.022	0.978	0.000
R57 Shock, not elsewhere classified	0.022	0.978	0.000
R64 Cachexia	0.022	0.978	0.000
R58 Haemorrhage, not elsewhere classified	0.022	0.978	0.000
R32 Unspecified urinary incontinence	0.022	0.978	0.000
R18 Ascites	0.022	0.978	0.000
R63.1 Polydipsia	0.021	0.979	0.000
R68 Other general symptoms and signs	0.021	0.979	0.000
R23 Other skin changes	0.021	0.979	0.000
R60.0 Localised oedema	0.021	0.979	0.000
R63.0 Anorexia	0.021	0.979	0.000
R61.9 Hyperhidrosis, unspecified	0.021	0.979	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.020	0.980	0.000
R21 Rash and other nonspecific skin eruption	0.020	0.980	0.000
R63.6 Insufficient intake of food and water due to self neglect	0.019	0.981	0.000
R63.5 Abnormal weight gain	0.019	0.981	0.000
R63.3 Feeding difficulties and mismanagement	0.019	0.981	0.000
R63.2 Polyphagia	0.019	0.981	0.000
R27 Other lack of coordination	0.019	0.981	0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.019	0.981	0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.019	0.981	0.000
R20.3 Hyperaesthesia	0.019	0.981	0.000
R20.1 Hypoaesthesia of skin	0.019	0.981	0.000
R20.0 Anaesthesia of skin	0.019	0.981	0.000
R13 Dysphagia	0.019	0.981	0.000
R52.9 Pain, unspecified	0.019	0.981	0.000
R95-R99 Ill-defined and unknown causes of mortality	0.018	0.982	0.000
R56 Convulsions, not elsewhere classified	0.018	0.982	0.000
R52.0 Acute pain	0.018	0.982	0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.018	0.982	0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.018	0.982	0.000
R14 Flatulence and related conditions	0.018	0.982	0.000
R52.1 Chronic intractable pain	0.018	0.982	0.000
R12 Heartburn	0.018	0.982	0.000
R82 Other abnormal findings in urine	0.018	0.982	0.000
R60.1 Generalised oedema	0.018	0.982	0.000
R61.1 Generalised hyperhidrosis	0.018	0.982	0.000
R61.0 Localised hyperhidrosis	0.018	0.982	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.018	0.982	0.000
R80 Isolated proteinuria	0.018	0.982	0.000
R60.9 Oedema, unspecified	0.017	0.983	0.000
R20.8 Other and unspecified disturbances of skin sensation	0.017	0.983	0.000
R23.2 Flushing	0.017	0.983	0.000
R29.4 Clicking hip	0.017	0.983	0.000
R29.3 Abnormal posture	0.017	0.983	0.000
R29.2 Abnormal reflex	0.017	0.983	0.000
R29.1 Meningismus	0.017	0.983	0.000
R29.0 Tetany	0.017	0.983	0.000
R23.3 Spontaneous ecchymoses	0.017	0.983	0.000
R23.1 Pallor	0.017	0.983	0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.017	0.983	0.000
R50 Fever of unknown origin	0.016	0.984	0.000
R19 Other symptoms and signs involving the digestive system and abdomen	0.016	0.984	0.000
R63.8 Other symptoms and signs concerning food and fluid intake	0.016	0.984	0.000
R27.0 Ataxia, unspecified	0.016	0.984	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.016	0.984	0.000
R26 Abnormalities of gait and mobility	0.016	0.984	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.016	0.984	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.016	0.984	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.016	0.984	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.016	0.984	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.016	0.984	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.016	0.984	0.000
R42 Dizziness and giddiness	0.016	0.984	0.000
R81 Glycosuria	0.016	0.984	0.000
R57.9 Shock, unspecified	0.016	0.984	0.000
R57.8 Other shock	0.016	0.984	0.000
R57.2 Septic shock	0.016	0.984	0.000
R57.1 Hypovolaemic shock	0.016	0.984	0.000
R57.0 Cardiogenic shock	0.016	0.984	0.000
R62.9 Lack of expected normal physiological development, unspecified	0.016	0.984	0.000
R62.8 Other lack of expected normal physiological development	0.016	0.984	0.000
R62.0 Delayed milestone	0.016	0.984	0.000
R65.9 Systemic Inflammatory Response Syndrome, unspecified	0.016	0.984	0.000
R65.3 Systemic Inflammatory Response Syndrome of non-infectious origin with organ failure	0.016	0.984	0.000
R65.2 Systemic Inflammatory Response Syndrome of non-infectious origin without organ failure	0.016	0.984	0.000
R65.1 Systemic Inflammatory Response Syndrome of infectious origin with organ failure	0.016	0.984	0.000
R65.0 Systemic Inflammatory Response Syndrome of infectious origin without organ failure	0.016	0.984	0.000
R25 Abnormal involuntary movements	0.016	0.984	0.000
R68.3 Clubbing of fingers	0.015	0.985	0.000
R68.2 Dry mouth, unspecified	0.015	0.985	0.000
R68.1 Nonspecific symptoms peculiar to infancy	0.015	0.985	0.000
R68.0 Hypothermia, not associated with low environmental temperature	0.015	0.985	0.000
R23.0 Cyanosis	0.015	0.985	0.000
R23.4 Changes in skin texture	0.015	0.985	0.000
R44 Other symptoms and signs involving general sensations and perceptions	0.015	0.985	0.000
R82.9 Other and unspecified abnormal finding in urine	0.015	0.985	0.000
R19.4 Change in bowel habit	0.015	0.985	0.000
R68.8 Other specified general symptoms and signs	0.015	0.985	0.000
M06 Other rheumatoid arthritis	0.015	0.985	0.000
R30-R39 Symptoms and signs involving the urinary system	0.015	0.985	0.000
R16.1 Splenomegaly, not elsewhere classified	0.014	0.986	0.000
R27.8 Other and unspecified lack of coordination	0.014	0.986	0.000
R46 Symptoms and signs involving appearance and behaviour	0.014	0.986	0.000
R43 Disturbances of smell and taste	0.014	0.986	0.000
R17 Unspecified jaundice	0.014	0.986	0.000
R41 Other symptoms and signs involving cognitive functions and awareness	0.014	0.986	0.000
R23.8 Other and unspecified skin changes	0.014	0.986	0.000
R16.0 Hepatomegaly, not elsewhere classified	0.013	0.986	0.000
R96 Other sudden death, cause unknown	0.013	0.986	0.000
R95 Sudden infant death syndrome	0.013	0.986	0.000
R99 Other ill-defined and unspecified causes of mortality	0.013	0.986	0.000
R98 Unattended death	0.013	0.986	0.000
R87 Abnormal findings in specimens from female genital organs	0.013	0.987	0.000
R56.0 Febrile convulsions	0.013	0.987	0.000
R16.2 Hepatomegaly with splenomegaly, not elsewhere classified	0.013	0.987	0.000
R89 Abnormal findings in specimens from other organs, systems and tissues	0.013	0.987	0.000
R86 Abnormal findings in specimens from male genital organs	0.013	0.987	0.000
R84 Abnormal findings in specimens from respiratory organs and thorax	0.013	0.987	0.000
R83 Abnormal findings in cerebrospinal fluid	0.013	0.987	0.000
R45 Symptoms and signs involving emotional state	0.013	0.987	0.000
R76 Other abnormal immunological findings in serum	0.013	0.987	0.000
R47-R49 Symptoms and signs involving speech and voice	0.013	0.987	0.000
R82.8 Abnormal findings on cytological and histological examination of urine	0.013	0.987	0.000
R82.7 Abnormal findings on microbiological examination of urine	0.013	0.987	0.000
R82.6 Abnormal urine levels of substances chiefly nonmedicinal as to source	0.013	0.987	0.000
R82.5 Elevated urine levels of drugs, medicaments and biological substances	0.013	0.987	0.000
R82.4 Acetonuria	0.013	0.987	0.000
R82.3 Haemoglobinuria	0.013	0.987	0.000
R82.2 Biliuria	0.013	0.987	0.000
R82.1 Myoglobinuria	0.013	0.987	0.000
R82.0 Chyluria	0.013	0.987	0.000
R72 Abnormality of white blood cells, not elsewhere classified	0.013	0.987	0.000
R26.3 Immobility	0.013	0.987	0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity	0.013	0.987	0.000
R10 Abdominal and pelvic pain	0.013	0.987	0.000
M06.4 Inflammatory polyarthropathy	0.012	0.988	0.000
R25.3 Fasciculation	0.012	0.988	0.000
M06.3 Rheumatoid nodule	0.012	0.988	0.000
R26.0 Ataxic gait	0.012	0.988	0.000
R78 Findings of drugs and other substances, not normally found in blood	0.012	0.988	0.000
R77 Other abnormalities of plasma proteins	0.012	0.988	0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.012	0.988	0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]	0.012	0.988	0.000
R71 Abnormality of red blood cells	0.012	0.988	0.000
R34 Anuria and oliguria	0.012	0.988	0.000
R50.2 Drug-induced fever	0.012	0.988	0.000
R50.1 Persistent fever	0.012	0.988	0.000
R41.3 Other amnesia	0.012	0.988	0.000
R19.6 Halitosis	0.012	0.988	0.000
R19.3 Abdominal rigidity	0.012	0.988	0.000
R19.2 Visible peristalsis	0.012	0.988	0.000
R19.1 Abnormal bowel sounds	0.012	0.988	0.000
R44.1 Visual hallucinations	0.012	0.988	0.000
R50.0 Fever with chills	0.012	0.988	0.000
R19.8 Other specified symptoms and signs involving the digestive system and abdomen	0.012	0.988	0.000
R26.1 Paralytic gait	0.012	0.988	0.000
R25.8 Other and unspecified abnormal involuntary movements	0.012	0.988	0.000
R50.8 Other specified fever	0.011	0.988	0.000
R25.0 Abnormal head movements	0.011	0.988	0.000
R44.3 Hallucinations, unspecified	0.011	0.989	0.000
R74 Abnormal serum enzyme levels	0.011	0.989	0.000
R40 Somnolence, stupor and coma	0.011	0.989	0.000
R73 Elevated blood glucose level	0.011	0.989	0.000
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.011	0.989	0.000
R44.2 Other hallucinations	0.011	0.989	0.000
R44.0 Auditory hallucinations	0.011	0.989	0.000
M06.8 Other specified rheumatoid arthritis	0.011	0.989	0.000
M06.2 Rheumatoid bursitis	0.011	0.989	0.000
M06.1 Adult-onset Still's disease	0.011	0.989	0.000
R76.8 Other specified abnormal immunological findings in serum	0.011	0.989	0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.011	0.989	0.000
R26.2 Difficulty in walking, not elsewhere classified	0.011	0.989	0.000
R36 Urethral discharge	0.011	0.989	0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.011	0.989	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.010	0.989	0.000
R25.1 Tremor, unspecified	0.010	0.989	0.000
M06.34 Rheumatoid nodule (Hand)	0.010	0.990	0.000
R10.2 Pelvic and perineal pain	0.010	0.990	0.000
R41.2 Retrograde amnesia	0.010	0.990	0.000
R10.0 Acute abdomen	0.010	0.990	0.000
R43.8 Other and unspecified disturbances of smell and taste	0.010	0.990	0.000
R43.2 Parageusia	0.010	0.990	0.000
R43.1 Parosmia	0.010	0.990	0.000
R43.0 Anosmia	0.010	0.990	0.000
R46.8 Other symptoms and signs involving appearance and behaviour	0.010	0.990	0.000
R46.7 Verbosity and circumstantial detail obscuring reason for contact	0.010	0.990	0.000
R46.6 Undue concern and preoccupation with stressful events	0.010	0.990	0.000
R46.5 Suspiciousness and marked evasiveness	0.010	0.990	0.000
R46.4 Slowness and poor responsiveness	0.010	0.990	0.000
R46.3 Overactivity	0.010	0.990	0.000
R46.2 Strange and inexplicable behaviour	0.010	0.990	0.000
R46.1 Bizarre personal appearance	0.010	0.990	0.000
R46.0 Very low level of personal hygiene	0.010	0.990	0.000
M06.0 Seronegative rheumatoid arthritis	0.010	0.990	0.000
R41.1 Anterograde amnesia	0.010	0.990	0.000
R56.8 Other and unspecified convulsions	0.010	0.990	0.000
R87.6 Abnormal cytological findings	0.010	0.990	0.000
R95.9 Sudden infant death syndrome without mention of autopsy	0.010	0.990	0.000
R95.0 Sudden infant death syndrome with mention of autopsy	0.010	0.990	0.000
R96.1 Death occurring less than 24 hours from onset of symptoms, not otherwise explained	0.010	0.990	0.000
R96.0 Instantaneous death	0.010	0.990	0.000
R87.9 Unspecified abnormal finding	0.010	0.990	0.000
R87.8 Other abnormal findings	0.010	0.990	0.000
R87.7 Abnormal histological findings	0.010	0.990	0.000
R87.5 Abnormal microbiological findings	0.010	0.990	0.000
R87.4 Abnormal immunological findings	0.010	0.990	0.000
R87.3 Abnormal level of substances chiefly nonmedicinal as to source	0.010	0.990	0.000
R87.2 Abnormal level of other drugs, medicaments and biological substances	0.010	0.990	0.000
R87.1 Abnormal level of hormones	0.010	0.990	0.000
R87.0 Abnormal level of enzymes	0.010	0.990	0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.010	0.990	0.000
R83.9 Unspecified abnormal finding	0.010	0.990	0.000
R83.8 Other abnormal findings	0.010	0.990	0.000
R83.7 Abnormal histological findings	0.010	0.990	0.000
R83.6 Abnormal cytological findings	0.010	0.990	0.000
R83.5 Abnormal microbiological findings	0.010	0.990	0.000
R83.4 Abnormal immunological findings	0.010	0.990	0.000
R83.3 Abnormal level of substances chiefly nonmedicinal as to source	0.010	0.990	0.000
R83.2 Abnormal level of other drugs, medicaments and biological substances	0.010	0.990	0.000
R83.1 Abnormal level of hormones	0.010	0.990	0.000
R83.0 Abnormal level of enzymes	0.010	0.990	0.000
R84.9 Unspecified abnormal finding	0.010	0.990	0.000
R84.8 Other abnormal findings	0.010	0.990	0.000
R84.7 Abnormal histological findings	0.010	0.990	0.000
R84.6 Abnormal cytological findings	0.010	0.990	0.000
R84.5 Abnormal microbiological findings	0.010	0.990	0.000
R84.4 Abnormal immunological findings	0.010	0.990	0.000
R84.3 Abnormal level of substances chiefly nonmedicinal as to source	0.010	0.990	0.000
R84.2 Abnormal level of other drugs, medicaments and biological substances	0.010	0.990	0.000
R84.1 Abnormal level of hormones	0.010	0.990	0.000
R84.0 Abnormal level of enzymes	0.010	0.990	0.000
R86.9 Unspecified abnormal finding	0.010	0.990	0.000
R86.8 Other abnormal findings	0.010	0.990	0.000
R86.7 Abnormal histological findings	0.010	0.990	0.000
R86.6 Abnormal cytological findings	0.010	0.990	0.000
R86.5 Abnormal microbiological findings	0.010	0.990	0.000
R86.4 Abnormal immunological findings	0.010	0.990	0.000
R86.3 Abnormal level of substances chiefly nonmedicinal as to source	0.010	0.990	0.000
R86.2 Abnormal level of other drugs, medicaments and biological substances	0.010	0.990	0.000
R86.1 Abnormal level of hormones	0.010	0.990	0.000
R86.0 Abnormal level of enzymes	0.010	0.990	0.000
R89.9 Unspecified abnormal finding	0.010	0.990	0.000
R89.8 Other abnormal findings	0.010	0.990	0.000
R89.7 Abnormal histological findings	0.010	0.990	0.000
R89.6 Abnormal cytological findings	0.010	0.990	0.000
R89.5 Abnormal microbiological findings	0.010	0.990	0.000
R89.4 Abnormal immunological findings	0.010	0.990	0.000
R89.3 Abnormal level of substances chiefly nonmedicinal as to source	0.010	0.990	0.000
R89.2 Abnormal level of other drugs, medicaments and biological substances	0.010	0.990	0.000
R89.1 Abnormal level of hormones	0.010	0.990	0.000
R89.0 Abnormal level of enzymes	0.010	0.990	0.000
R45.7 State of emotional shock and stress, unspecified	0.010	0.990	0.000
R45.6 Physical violence	0.010	0.990	0.000
R45.5 Hostility	0.010	0.990	0.000
R45.4 Irritability and anger	0.010	0.990	0.000
R45.3 Demoralisation and apathy	0.010	0.990	0.000
R45.2 Unhappiness	0.010	0.990	0.000
R45.0 Nervousness	0.010	0.990	0.000
R76.9 Abnormal immunological finding in serum, unspecified	0.010	0.990	0.000
R76.2 False-positive serological test for syphilis	0.010	0.990	0.000
R76.1 Abnormal reaction to tuberculin test	0.010	0.990	0.000
R76.0 Raised antibody titer	0.010	0.990	0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified	0.009	0.990	0.000
R85.9 Unspecified abnormal finding	0.009	0.990	0.000
R85.8 Other abnormal findings	0.009	0.990	0.000
R85.7 Abnormal histological findings	0.009	0.990	0.000
R85.6 Abnormal cytological findings	0.009	0.990	0.000
R85.4 Abnormal immunological findings	0.009	0.990	0.000
R85.3 Abnormal level of substances chiefly nonmedicinal as to source	0.009	0.990	0.000
R85.2 Abnormal level of other drugs, medicaments and biological substances	0.009	0.990	0.000
R85.1 Abnormal level of hormones	0.009	0.990	0.000
R85.0 Abnormal level of enzymes	0.009	0.990	0.000
R45.1 Restlessness and agitation	0.009	0.990	0.000
R45.8 Other symptoms and signs involving emotional state	0.009	0.991	0.000
R59 Enlarged lymph nodes	0.009	0.991	0.000
R85.5 Abnormal microbiological findings	0.009	0.991	0.000
R25.2 Cramp and spasm	0.009	0.991	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.009	0.991	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.009	0.991	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.009	0.991	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.009	0.991	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.009	0.991	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.009	0.991	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.009	0.991	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.009	0.991	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.009	0.991	0.000
R79 Other abnormal findings of blood chemistry	0.009	0.991	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.009	0.991	0.000
M06.38 Rheumatoid nodule (Other)	0.009	0.991	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.009	0.991	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.009	0.991	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.009	0.991	0.000
M06.33 Rheumatoid nodule (Forearm)	0.009	0.991	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.009	0.991	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.009	0.991	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.009	0.991	0.000
R70.1 Abnormal plasma viscosity	0.009	0.991	0.000
R70.0 Elevated erythrocyte sedimentation rate	0.009	0.991	0.000
R77.9 Abnormality of plasma protein, unspecified	0.009	0.991	0.000
R77.8 Other specified abnormalities of plasma proteins	0.009	0.991	0.000
R77.2 Abnormality of alphafetoprotein	0.009	0.991	0.000
R77.1 Abnormality of globulin	0.009	0.991	0.000
R77.0 Abnormality of albumin	0.009	0.991	0.000
R78.9 Finding of unspecified substance, not normally found in blood	0.009	0.991	0.000
R78.8 Finding of other specified substances, not normally found in blood	0.009	0.991	0.000
R78.7 Finding of abnormal level of heavy metals in blood	0.009	0.991	0.000
R78.6 Finding of steroid agent in blood	0.009	0.991	0.000
R78.5 Finding of psychotropic drug in blood	0.009	0.991	0.000
R78.4 Finding of other drugs of addictive potential in blood	0.009	0.991	0.000
R78.3 Finding of hallucinogen in blood	0.009	0.991	0.000
R78.2 Finding of cocaine in blood	0.009	0.991	0.000
R78.1 Finding of opiate drug in blood	0.009	0.991	0.000
R78.0 Finding of alcohol in blood	0.009	0.991	0.000
R10.1 Pain localised to upper abdomen	0.009	0.991	0.000
R26.8 Other and unspecified abnormalities of gait and mobility	0.009	0.991	0.000
R93 Abnormal findings on diagnostic imaging of other body structures	0.009	0.991	0.000
Z36.0 Antenatal screening for chromosomal anomalies	0.008	0.991	0.000
R19.0 Intra-abdominal and pelvic swelling, mass and lump	0.008	0.992	0.000
R74.9 Abnormal level of unspecified serum enzyme	0.008	0.992	0.000
R74.0 Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]	0.008	0.992	0.000
R40.1 Stupor	0.008	0.992	0.000
R19.5 Other fecal abnormalities	0.008	0.992	0.000
R73.9 Hyperglycaemia, unspecified	0.008	0.992	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.008	0.992	0.000
M06.18 Adult-onset Still's disease (Other)	0.008	0.992	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.008	0.992	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.008	0.992	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.008	0.992	0.000
M06.14 Adult-onset Still's disease (Hand)	0.008	0.992	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.008	0.992	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.008	0.992	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.008	0.992	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.008	0.992	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.008	0.992	0.000
M06.28 Rheumatoid bursitis (Other)	0.008	0.992	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.008	0.992	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.008	0.992	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.008	0.992	0.000
M06.24 Rheumatoid bursitis (Hand)	0.008	0.992	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.008	0.992	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.008	0.992	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.008	0.992	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.008	0.992	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.008	0.992	0.000
M06.88 Other specified rheumatoid arthritis (Other)	0.008	0.992	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.008	0.992	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.008	0.992	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.008	0.992	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.008	0.992	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.008	0.992	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.008	0.992	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.008	0.992	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.008	0.992	0.000
R92 Abnormal findings on diagnostic imaging of breast	0.008	0.992	0.000
Z36 Antenatal screening	0.008	0.992	0.000
R79.0 Abnormal level of blood mineral	0.008	0.992	0.000
R30 Pain associated with micturition	0.008	0.992	0.000
R22.3 Localised swelling, mass and lump, upper limb	0.008	0.992	0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.008	0.992	0.000
R47 Speech disturbances, not elsewhere classified	0.008	0.992	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.007	0.992	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.007	0.992	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.007	0.992	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.007	0.992	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.007	0.992	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.007	0.992	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.007	0.992	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.007	0.992	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.007	0.992	0.000
R74.8 Abnormal levels of other serum enzymes	0.007	0.992	0.000
R50.9 Fever, unspecified	0.008	0.992	0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract	0.008	0.992	0.000
R40.0 Somnolence	0.007	0.993	0.000
R49 Voice disturbances	0.007	0.993	0.000
R22.7 Localised swelling, mass and lump, multiple sites	0.007	0.993	0.000
R73.0 Abnormal glucose tolerance test	0.007	0.993	0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.007	0.993	0.000
R48.8 Other and unspecified symbolic dysfunctions	0.007	0.993	0.000
R48.2 Apraxia	0.007	0.993	0.000
R48.1 Agnosia	0.007	0.993	0.000
R48.0 Dyslexia and alexia	0.007	0.993	0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified	0.007	0.993	0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods	0.007	0.993	0.000
R22.1 Localised swelling, mass and lump, neck	0.007	0.993	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.007	0.993	0.000
R90 Abnormal findings on diagnostic imaging of central nervous system	0.007	0.993	0.000
R40.2 Coma, unspecified	0.007	0.993	0.000
R94 Abnormal results of function studies	0.007	0.993	0.000
Z36.8 Other antenatal screening	0.007	0.993	0.000
N83.2 Other and unspecified ovarian cysts	0.000	0.993	0.007
R10.4 Other and unspecified abdominal pain	0.007	0.993	0.000
R15 Faecal incontinence	0.006	0.993	0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system	0.007	0.993	0.000
R93.6 Abnormal findings on diagnostic imaging of limbs	0.007	0.993	0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.006	0.994	0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.006	0.994	0.000
R22.0 Localised swelling, mass and lump, head	0.006	0.994	0.000
R22.9 Localised swelling, mass and lump, unspecified	0.006	0.994	0.000
Z36.9 Antenatal screening, unspecified	0.006	0.994	0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.006	0.994	0.000
R41.0 Disorientation, unspecified	0.006	0.994	0.000
Z36.5 Antenatal screening for isoimmunisation	0.006	0.994	0.000
Z36.2 Other antenatal screening based on amniocentesis	0.006	0.994	0.000
Z36.1 Antenatal screening for raised alphafetoprotein level	0.006	0.994	0.000
R22.4 Localised swelling, mass and lump, lower limb	0.006	0.994	0.000
R30.1 Vesical tenesmus	0.006	0.994	0.000
M05-M14 Inflammatory polyarthropathies	0.006	0.994	0.000
R59.9 Enlarged lymph nodes, unspecified	0.006	0.994	0.000
R22.2 Localised swelling, mass and lump, trunk	0.006	0.994	0.000
R30.9 Painful micturition, unspecified	0.005	0.994	0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures	0.005	0.994	0.000
R49.8 Other and unspecified voice disturbances	0.005	0.994	0.000
R49.2 Hypernasality and hyponasality	0.005	0.994	0.000
R49.1 Aphonia	0.005	0.994	0.000
H26.9 Cataract, unspecified	0.000	0.994	0.006
R47.1 Dysarthria and anarthria	0.005	0.994	0.000
R79.9 Abnormal finding of blood chemistry, unspecified	0.005	0.994	0.000
R39 Other symptoms and signs involving the urinary system	0.005	0.994	0.000
R94.5 Abnormal results of liver function studies	0.005	0.994	0.000
R47.0 Dysphasia and aphasia	0.005	0.995	0.000
R94.8 Abnormal results of function studies of other organs and systems	0.005	0.995	0.000
R94.7 Abnormal results of other endocrine function studies	0.005	0.995	0.000
R94.6 Abnormal results of thyroid function studies	0.005	0.995	0.000
R94.2 Abnormal results of pulmonary function studies	0.005	0.995	0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses	0.005	0.995	0.000
R94.0 Abnormal results of function studies of central nervous system	0.005	0.995	0.000
R94.4 Abnormal results of kidney function studies	0.005	0.995	0.000
R90.0 Intracranial space-occupying lesion	0.005	0.995	0.000
M11 Other crystal arthropathies	0.005	0.995	0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.005	0.995	0.000
R10.3 Pain localised to other parts of lower abdomen	0.005	0.995	0.000
R69 Unknown and unspecified causes of morbidity	0.005	0.995	0.000
R59.1 Generalised enlarged lymph nodes	0.004	0.995	0.000
R47.8 Other and unspecified speech disturbances	0.004	0.995	0.000
M07 Psoriatic and enteropathic arthropathies	0.004	0.995	0.000
M14 Arthropathies in other diseases classified elsewhere	0.004	0.995	0.000
M12 Other specific arthropathies	0.004	0.995	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.004	0.995	0.000
M08 Juvenile arthritis	0.004	0.995	0.000
M05 Seropositive rheumatoid arthritis	0.004	0.995	0.000
M13 Other arthritis	0.004	0.996	0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.004	0.996	0.000
R01 Cardiac murmurs and other cardiac sounds	0.004	0.996	0.000
R39.2 Extrarenal uraemia	0.004	0.996	0.000
R39.0 Extravasation of urine	0.004	0.996	0.000
R90.8 Other abnormal findings on diagnostic imaging of central nervous system	0.004	0.996	0.000
M11.2 Other chondrocalcinosis	0.004	0.996	0.000
R01.1 Cardiac murmur, unspecified	0.004	0.996	0.000
M10 Gout	0.004	0.996	0.000
R59.0 Localised enlarged lymph nodes	0.003	0.996	0.000
M11.9 Crystal arthropathy, unspecified	0.004	0.996	0.000
M11.8 Other specified crystal arthropathies	0.004	0.996	0.000
M11.1 Familial chondrocalcinosis	0.004	0.996	0.000
M11.0 Hydroxyapatite deposition disease	0.004	0.996	0.000
R09.1 Pleurisy	0.004	0.996	0.000
R30.0 Dysuria	0.003	0.996	0.000
M07.3 Other psoriatic arthropathies	0.003	0.996	0.000
M07.6 Other enteropathic arthropathies	0.003	0.996	0.000
M07.5 Arthropathy in ulcerative colitis	0.003	0.996	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.003	0.996	0.000
M07.2 Psoriatic spondylitis	0.003	0.996	0.000
M07.1 Arthritis mutilans	0.003	0.996	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.003	0.996	0.000
R09.2 Respiratory arrest	0.003	0.996	0.000
R09.0 Asphyxia	0.003	0.996	0.000
M08.9 Juvenile arthritis, unspecified	0.003	0.996	0.000
M08.8 Other juvenile arthritis	0.003	0.996	0.000
M08.4 Pauciarticular juvenile arthritis	0.003	0.996	0.000
M08.3 Juvenile polyarthritis (seronegative)	0.003	0.996	0.000
M08.2 Juvenile arthritis with systemic onset	0.003	0.996	0.000
M08.1 Juvenile ankylosing spondylitis	0.003	0.996	0.000
M08.0 Juvenile rheumatoid arthritis	0.003	0.996	0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.003	0.996	0.000
M09.2 Juvenile arthritis in ulcerative colitis	0.003	0.996	0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.003	0.996	0.000
M09.0 Juvenile arthritis in psoriasis	0.003	0.996	0.000
M12.8 Other specific arthropathies, not elsewhere classified	0.003	0.996	0.000
M12.5 Traumatic arthropathy	0.003	0.996	0.000
M12.4 Intermittent hydrarthrosis	0.003	0.996	0.000
M12.3 Palindromic rheumatism	0.003	0.996	0.000
M12.2 Villonodular synovitis (pigmented)	0.003	0.996	0.000
M12.1 Kaschin-Beck disease	0.003	0.996	0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.003	0.996	0.000
M14.8 Arthropathies in other specified diseases classified elsewhere	0.003	0.996	0.000
M14.6 Neuropathic arthropathy	0.003	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations