TreeWAS – Variant ID: rs13236930

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C34.9 Bronchus or lung, unspecified	0.000	0.972	0.028
C34 Malignant neoplasm of bronchus and lung	0.000	0.979	0.021
C34.3 Lower lobe, bronchus or lung	0.000	0.981	0.019
E05.9 Thyrotoxicosis, unspecified	0.000	0.983	0.017
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.983	0.016
C34.1 Upper lobe, bronchus or lung	0.000	0.984	0.016
E00-E07 Disorders of thyroid gland	0.000	0.984	0.016
C34.2 Middle lobe, bronchus or lung	0.000	0.984	0.016
E04 Other non-toxic goitre	0.000	0.984	0.016
E07 Other disorders of thyroid	0.000	0.985	0.015
C34.8 Overlapping lesion of bronchus and lung	0.000	0.985	0.015
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.985	0.015
E06 Thyroiditis	0.000	0.985	0.015
E06.3 Autoimmune thyroiditis	0.000	0.985	0.015
E07.9 Disorder of thyroid, unspecified	0.000	0.985	0.015
E04.2 Non-toxic multinodular goitre	0.000	0.986	0.014
E04.9 Non-toxic goitre, unspecified	0.000	0.986	0.014
E04.1 Non-toxic single thyroid nodule	0.000	0.986	0.014
C34.0 Main bronchus	0.000	0.986	0.013
E07.8 Other specified disorders of thyroid	0.000	0.987	0.013
E05.5 Thyroid crisis or storm	0.000	0.988	0.012
E05.4 Thyrotoxicosis factitia	0.000	0.988	0.012
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.988	0.012
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.988	0.012
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.988	0.012
E00 Congenital iodine-deficiency syndrome	0.000	0.988	0.012
E04.8 Other specified non-toxic goitre	0.000	0.988	0.012
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.988	0.011
E07.1 Dyshormogenetic goitre	0.000	0.989	0.011
E07.0 Hypersecretion of calcitonin	0.000	0.989	0.011
E06.5 Other chronic thyroiditis	0.000	0.989	0.011
E06.4 Drug-induced thyroiditis	0.000	0.989	0.011
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.989	0.011
E06.1 Subacute thyroiditis	0.000	0.989	0.011
E06.0 Acute thyroiditis	0.000	0.989	0.011
E06.9 Thyroiditis, unspecified	0.000	0.989	0.010
E05.8 Other thyrotoxicosis	0.000	0.990	0.010
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.990	0.010
R94.5 Abnormal results of liver function studies	0.010	0.990	0.000
E04.0 Non-toxic diffuse goitre	0.000	0.991	0.009
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.991	0.009
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.991	0.009
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.991	0.009
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.991	0.009
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.991	0.009
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.991	0.009
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.991	0.009
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.991	0.009
K58.0 Irritable bowel syndrome with diarrhoea	0.008	0.992	0.000
K51.2 Ulcerative (chronic) proctitis	0.008	0.992	0.000
K51.8 Other ulcerative colitis	0.008	0.992	0.000
K51 Ulcerative colitis	0.008	0.992	0.000
K51.4 Pseudopolyposis of colon	0.007	0.993	0.000
Y43.3 Other antineoplastic drugs	0.007	0.993	0.000
K51.5 Mucosal proctocolitis	0.007	0.993	0.000
E87.6 Hypokalaemia	0.007	0.993	0.000
E03 Other hypothyroidism	0.000	0.994	0.006
K51.9 Ulcerative colitis, unspecified	0.006	0.994	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.005	0.995	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.995	0.005
K51.0 Ulcerative (chronic) enterocolitis	0.005	0.995	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.005	0.995	0.000
E03.5 Myxoedema coma	0.000	0.995	0.005
E03.4 Atrophy of thyroid (acquired)	0.000	0.995	0.005
E03.3 Postinfectious hypothyroidism	0.000	0.995	0.005
E03.1 Congenital hypothyroidism without goitre	0.000	0.995	0.005
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.995	0.005
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.000	0.995	0.005
M47.96 Spondylosis, unspecified (Lumbar region)	0.000	0.995	0.005
Y43 Primarily systemic agents	0.005	0.995	0.000
S70.9 Superficial injury of hip and thigh, unspecified	0.004	0.996	0.000
D41.4 Bladder	0.004	0.996	0.000
Y43.4 Immunosuppressive agents	0.004	0.996	0.000
M22.8 Other disorders of patella	0.000	0.996	0.004
E03.8 Other specified hypothyroidism	0.000	0.996	0.004
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.000	0.996	0.003
C31 Malignant neoplasm of accessory sinuses	0.000	0.996	0.003
C37 Malignant neoplasm of thymus	0.000	0.996	0.003
C33 Malignant neoplasm of trachea	0.000	0.996	0.003
Y43.9 Primarily systemic agent, unspecified	0.003	0.996	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.003	0.996	0.000
Y43.6 Enzymes, not elsewhere classified	0.003	0.996	0.000
Y43.5 Acidifying and alkalising agents	0.003	0.996	0.000
Y43.2 Antineoplastic natural products	0.003	0.996	0.000
Y43.1 Antineoplastic antimetabolites	0.003	0.996	0.000
Q38.7 Pharyngeal pouch	0.000	0.996	0.003
S79.9 Unspecified injury of hip and thigh	0.003	0.997	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.000	0.997	0.003
R94 Abnormal results of function studies	0.003	0.997	0.000
M22.4 Chondromalacia patellae	0.000	0.997	0.003
Y40.0 Penicillins	0.003	0.997	0.000
S70 Superficial injury of hip and thigh	0.003	0.997	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.000	0.997	0.003
Y43.0 Antiallergic and antiemetic drugs	0.003	0.997	0.000
M22.2 Patellofemoral disorders	0.000	0.997	0.003
M22 Disorders of patella	0.000	0.997	0.003
S79 Other and unspecified injuries of hip and thigh	0.003	0.997	0.000
M19.01 Primary arthrosis of other joints (Shoulder region)	0.000	0.997	0.003
S70.8 Other superficial injuries of hip and thigh	0.003	0.997	0.000
K09.0 Developmental odontogenic cysts	0.000	0.997	0.003
C31.9 Accessory sinus, unspecified	0.000	0.997	0.003
C31.8 Overlapping lesion of accessory sinuses	0.000	0.997	0.003
C31.3 Sphenoidal sinus	0.000	0.997	0.003
C31.2 Frontal sinus	0.000	0.997	0.003
C31.1 Ethmoidal sinus	0.000	0.997	0.003
C31.0 Maxillary sinus	0.000	0.997	0.003
C39.9 Ill-defined sites within the respiratory system	0.000	0.997	0.003
C39.8 Overlapping lesion of respiratory and intrathoracic organs	0.000	0.997	0.003
C39.0 Upper respiratory tract, part unspecified	0.000	0.997	0.003
C32 Malignant neoplasm of larynx	0.000	0.997	0.003
R27.0 Ataxia, unspecified	0.003	0.997	0.000
M47.9 Spondylosis, unspecified	0.000	0.997	0.003
C67.2 Lateral wall of bladder	0.000	0.997	0.003
R94.2 Abnormal results of pulmonary function studies	0.003	0.997	0.000
R94.0 Abnormal results of function studies of central nervous system	0.003	0.997	0.000
C30.1 Middle ear	0.000	0.997	0.002
R94.7 Abnormal results of other endocrine function studies	0.003	0.997	0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses	0.003	0.997	0.000
S79.8 Other specified injuries of hip and thigh	0.003	0.997	0.000
Y40 Systemic antibiotics	0.003	0.997	0.000
R94.6 Abnormal results of thyroid function studies	0.003	0.997	0.000
S01.5 Open wound of lip and oral cavity	0.003	0.997	0.000
S70-S79 Injuries to the hip and thigh	0.003	0.997	0.000
S70.7 Multiple superficial injuries of hip and thigh	0.002	0.997	0.000
M47.99 Spondylosis, unspecified (Site unspecified)	0.000	0.997	0.003
C38.8 Overlapping lesion of heart, mediastinum and pleura	0.000	0.997	0.002
C38.3 Mediastinum, part unspecified	0.000	0.997	0.002
C38.2 Posterior mediastinum	0.000	0.997	0.002
C38.1 Anterior mediastinum	0.000	0.997	0.002
C38.0 Heart	0.000	0.997	0.002
R94.4 Abnormal results of kidney function studies	0.002	0.997	0.000
Y40.3 Macrolides	0.002	0.997	0.000
M22.1 Recurrent subluxation of patella	0.000	0.997	0.002
M22.0 Recurrent dislocation of patella	0.000	0.997	0.002
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.002	0.997	0.000
M22.3 Other derangements of patella	0.000	0.997	0.002
N36.8 Other specified disorders of urethra	0.002	0.997	0.000
R94.8 Abnormal results of function studies of other organs and systems	0.002	0.998	0.000
S73.0 Dislocation of hip	0.002	0.998	0.000
Y42.5 Other oestrogens and progestogens	0.002	0.998	0.000
S79.7 Multiple injuries of hip and thigh	0.002	0.998	0.000
I24.8 Other forms of acute ischaemic heart disease	0.000	0.998	0.002
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.002	0.998	0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.000	0.998	0.002
Z97.4 Presence of external hearing-aid	0.000	0.998	0.002
C30.0 Nasal cavity	0.000	0.998	0.002
T78.3 Angioneurotic oedema	0.002	0.998	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.002	0.998	0.000
S70.1 Contusion of thigh	0.002	0.998	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.002	0.998	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.002	0.998	0.000
C32.8 Overlapping lesion of larynx	0.000	0.998	0.002
C32.3 Laryngeal cartilage	0.000	0.998	0.002
C32.2 Subglottis	0.000	0.998	0.002
Y40.7 Antifungal antibiotics, systemically used	0.002	0.998	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.002	0.998	0.000
T78.4 Allergy, unspecified	0.002	0.998	0.000
S81.8 Open wound of other parts of lower leg	0.000	0.998	0.002
M47.95 Spondylosis, unspecified (Thoracolumbar region)	0.000	0.998	0.002
M47.93 Spondylosis, unspecified (Cervicothoracic region)	0.000	0.998	0.002
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)	0.000	0.998	0.002
M47.94 Spondylosis, unspecified (Thoracic region)	0.000	0.998	0.002
Y46.2 Hydantoin derivatives	0.002	0.998	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.000	0.998	0.002
S71 Open wound of hip and thigh	0.002	0.998	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.002	0.998	0.000
M47.92 Spondylosis, unspecified (Cervical region)	0.000	0.998	0.002
C38.4 Pleura	0.000	0.998	0.002
R94.3 Abnormal results of cardiovascular function studies	0.002	0.998	0.000
T40.4 Other synthetic narcotics	0.002	0.998	0.000
Y40.6 Rifamycins	0.002	0.998	0.000
Y40.5 Aminoglycosides	0.002	0.998	0.000
Y40.4 Tetracyclines	0.002	0.998	0.000
Y40.2 Chloramphenicol group	0.002	0.998	0.000
S78 Traumatic amputation of hip and thigh	0.002	0.998	0.000
S77 Crushing injury of hip and thigh	0.002	0.998	0.000
S75 Injury of blood vessels at hip and thigh level	0.002	0.998	0.000
S74 Injury of nerves at hip and thigh level	0.002	0.998	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.002	0.998	0.000
C32.1 Supraglottis	0.000	0.998	0.002
S70.0 Contusion of hip	0.002	0.998	0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)	0.000	0.998	0.002
C32.9 Larynx, unspecified	0.000	0.998	0.002
M22.9 Disorder of patella, unspecified	0.000	0.998	0.002
S76 Injury of muscle and tendon at hip and thigh level	0.002	0.998	0.000
M22.10 Recurrent subluxation of patella, unspecified knee	0.000	0.998	0.002
I35.2 Aortic (valve) stenosis with insufficiency	0.002	0.998	0.000
N48.0 Leukoplakia of penis	0.002	0.998	0.000
S73.1 Sprain and strain of hip	0.002	0.998	0.000
M77.91 Enthesopathy, unspecified (Shoulder region)	0.000	0.998	0.002
Y42.9 Other and unspecified hormone antagonists	0.002	0.998	0.000
Y42.4 Oral contraceptives	0.002	0.998	0.000
Y42.2 Antithyroid drugs	0.002	0.998	0.000
Y42.1 Thyroid hormones and substitutes	0.002	0.998	0.000
C32.0 Glottis	0.000	0.998	0.002
Z83.3 Family history of diabetes mellitus	0.002	0.998	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
Y46.6 Other and unspecified antiepileptics	0.002	0.998	0.000
X62.9 Unspecified place	0.002	0.998	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.002	0.998	0.000
S71.1 Open wound of thigh	0.002	0.998	0.000
Y40.8 Other systemic antibiotics	0.002	0.998	0.000
D41.2 Ureter	0.002	0.998	0.000
Q38.8 Other congenital malformations of pharynx	0.000	0.998	0.002
Q38.6 Other congenital malformations of mouth	0.000	0.998	0.002
Q38.5 Congenital malformations of palate, not elsewhere classified	0.000	0.998	0.002
Q38.4 Congenital malformations of salivary glands and ducts	0.000	0.998	0.002
Q38.3 Other congenital malformations of tongue	0.000	0.998	0.002
Q38.2 Macroglossia	0.000	0.998	0.002
Q38.1 Ankyloglossia	0.000	0.998	0.002
Q38.0 Congenital malformations of lips, not elsewhere classified	0.000	0.998	0.002
S71.8 Open wound of other and unspecified parts of pelvic girdle	0.002	0.998	0.000
S71.7 Multiple open wounds of of hip and thigh	0.002	0.998	0.000
S71.0 Open wound of hip	0.002	0.998	0.000
Y46.8 Antispasticity drugs	0.002	0.998	0.000
Y46.7 Anti-Parkinsonism drugs	0.002	0.998	0.000
Y46.5 Valproic acid	0.002	0.998	0.000
Y46.3 Deoxybarbiturates	0.002	0.998	0.000
Y46.1 Oxazolidinediones	0.002	0.998	0.000
Y46.0 Succinimides	0.002	0.998	0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.002	0.998	0.000
T78 Adverse effects, not elsewhere classified	0.002	0.998	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.000	0.998	0.002
Q21.1 Atrial septal defect	0.000	0.998	0.002
K58 Irritable bowel syndrome	0.002	0.998	0.000
Y59 Other and unspecified vaccines and biological substances	0.002	0.998	0.000
Y58 Bacterial vaccines	0.002	0.998	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.002	0.998	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
S82.60 Fracture of lateral malleolus (closed)	0.002	0.998	0.000
M19.0 Primary arthrosis of other joints	0.000	0.998	0.002
S74.9 Injury of unspecified nerve at hip and thigh level	0.002	0.998	0.000
S74.8 Injury of other nerves at hip and thigh level	0.002	0.998	0.000
S74.7 Injury of multiple nerves at hip and thigh level	0.002	0.998	0.000
S74.2 Injury of cutaneous sensory nerve at hip and thigh level	0.002	0.998	0.000
S74.1 Injury of femoral nerve at hip and thigh level	0.002	0.998	0.000
S74.0 Injury of sciatic nerve at hip and thigh level	0.002	0.998	0.000
S75.9 Injury of unspecified blood vessel at hip and thigh level	0.002	0.998	0.000
S75.8 Injury of other blood vessels at hip and thigh level	0.002	0.998	0.000
S75.7 Injury of multiple blood vessels at hip and thigh level	0.002	0.998	0.000
S75.2 Injury of greater saphenous vein at hip and thigh level	0.002	0.998	0.000
S75.1 Injury of femoral vein at hip and thigh level	0.002	0.998	0.000
S75.0 Injury of femoral artery	0.002	0.998	0.000
S77.2 Crushing injury of hip with thigh	0.002	0.998	0.000
S77.1 Crushing injury of thigh	0.002	0.998	0.000
S77.0 Crushing injury of hip	0.002	0.998	0.000
S78.9 Traumatic amputation of hip and thigh, level unspecified	0.002	0.998	0.000
S78.1 Traumatic amputation at level between hip and knee	0.002	0.998	0.000
S78.0 Traumatic amputation at hip joint	0.002	0.998	0.000
T91.2 Sequelae of other fracture of thorax and pelvis	0.002	0.998	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.998	0.002
S76.1 Injury of quadriceps muscle and tendon	0.002	0.998	0.000
S76.7 Injury of multiple muscles and tendons at hip and thigh level	0.002	0.998	0.000
S76.3 Injury of muscle and tendon of the posterior muscle group at thigh level	0.002	0.998	0.000
S76.2 Injury of adductor muscle and tendon of thigh	0.002	0.998	0.000
S76.0 Injury of muscle and tendon of hip	0.002	0.998	0.000
Y41.5 Antiviral drugs	0.002	0.998	0.000
Y46.4 Iminostilbenes	0.002	0.998	0.000
Y48 Anaesthetics and therapeutic gases	0.002	0.998	0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.000	0.998	0.002
Y44 Agents primarily affecting blood constituents	0.002	0.998	0.000
K09.8 Other cysts of oral region, not elsewhere classified	0.000	0.998	0.002
M50.2 Other cervical disk displacement	0.000	0.998	0.002
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.002	0.998	0.000
K50-K52 Noninfective enteritis and colitis	0.002	0.998	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.998	0.002
S76.4 Injury of other and unspecified muscles and tendons at thigh level	0.002	0.998	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
I24 Other acute ischaemic heart diseases	0.000	0.998	0.002
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.002	0.998	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.002	0.998	0.000
O86.4 Pyrexia of unknown origin following delivery	0.002	0.998	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.002	0.998	0.000
Y41.4 Anthelminthics	0.002	0.998	0.000
Y41.3 Other antiprotozoal drugs	0.002	0.998	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.002	0.998	0.000
Y41.1 Antimycobacterial drugs	0.002	0.998	0.000
Y41.0 Sulphonamides	0.002	0.998	0.000
T78.8 Other adverse effects, not elsewhere classified	0.002	0.998	0.000
T78.2 Anaphylactic shock, unspecified	0.002	0.998	0.000
Y44.5 Thrombolytic drugs	0.002	0.998	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.002	0.998	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.000	0.998	0.002
S72 Fracture of femur	0.002	0.998	0.000
M19.00 Primary arthrosis of other joints (Multiple sites)	0.000	0.998	0.002
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.002	0.998	0.000
D41.9 Urinary organ, unspecified	0.001	0.998	0.000
D41.7 Other urinary organs	0.001	0.998	0.000
D41.3 Urethra	0.001	0.998	0.000
D41.1 Renal pelvis	0.001	0.998	0.000
W22.9 Unspecified place	0.000	0.998	0.002
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.000
Y48.2 Other and unspecified general anaesthetics	0.002	0.998	0.000
K09 Cysts of oral region, not elsewhere classified	0.000	0.998	0.002
T92.1 Sequelae of fracture of arm	0.002	0.998	0.000
M19.04 Primary arthrosis of other joints (Hand)	0.000	0.998	0.002
M19.02 Primary arthrosis of other joints (Upper arm)	0.000	0.998	0.002
J35.8 Other chronic diseases of tonsils and adenoids	0.002	0.998	0.000
G55.3 Nerve root and plexus compressions in other dorsopathies	0.000	0.998	0.002
S72.1 Pertrochanteric fracture	0.002	0.998	0.000
T78.9 Adverse effect, unspecified	0.001	0.998	0.000
M19.03 Primary arthrosis of other joints (Forearm)	0.000	0.998	0.002
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.001	0.998	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.001	0.998	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.001	0.998	0.000
Y47.4 Bromine compounds	0.001	0.998	0.000
Y47.3 Paraldehyde	0.001	0.998	0.000
Y47.2 Chloral derivatives	0.001	0.998	0.000
Y47.1 Benzodiazepines	0.001	0.998	0.000
Y47.0 Barbiturates, not elsewhere classified	0.001	0.998	0.000
Y50.9 Central nervous system stimulant, unspecified	0.001	0.998	0.000
Y50.8 Other central nervous system stimulants	0.001	0.998	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.001	0.998	0.000
Y50.1 Opioid receptor antagonists	0.001	0.998	0.000
Y50.0 Analeptics	0.001	0.998	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.001	0.998	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.001	0.998	0.000
Y55.5 Anticommon cold drugs	0.001	0.998	0.000
Y55.4 Expectorants	0.001	0.998	0.000
Y55.3 Antitussives	0.001	0.998	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.001	0.998	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.001	0.998	0.000
Y55.0 Oxytocic drugs	0.001	0.998	0.000
Y58.9 Other and unspecified bacterial vaccines	0.001	0.998	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.001	0.998	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.001	0.998	0.000
Y58.5 Diphtheria vaccine	0.001	0.998	0.000
Y58.4 Tetanus vaccine	0.001	0.998	0.000
Y58.3 Plague vaccine	0.001	0.998	0.000
Y58.2 Cholera vaccine	0.001	0.998	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.001	0.998	0.000
Y58.0 BCG vaccine	0.001	0.998	0.000
Y59.9 Vaccine or biological substance, unspecified	0.001	0.998	0.000
Y59.8 Other specified vaccines and biological substances	0.001	0.998	0.000
Y59.3 Immunoglobulin	0.001	0.998	0.000
Y59.2 Protozoal vaccines	0.001	0.998	0.000
Y59.1 Rickettsial vaccines	0.001	0.998	0.000
Y59.0 Viral vaccines	0.001	0.998	0.000
M19.08 Primary arthrosis of other joints (Other)	0.000	0.998	0.001
M19.06 Primary arthrosis of other joints-Lower leg	0.000	0.998	0.001
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.000	0.998	0.001
S76.10 Unspecified injury of quadriceps muscle, fascia and tendon	0.001	0.998	0.000
Y40.9 Systemic antibiotic, unspecified	0.001	0.998	0.001
Y48.5 Therapeutic gases	0.001	0.998	0.000
Y48.1 Parenteral anaesthetics	0.001	0.998	0.000
Y48.0 Inhaled anaesthetics	0.001	0.998	0.000
M19.09 Primary arthrosis of other joints (Site unspecified)	0.000	0.998	0.001
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.001	0.998	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.001	0.998	0.000
Y44.7 Plasma substitutes	0.001	0.998	0.000
Y44.6 Natural blood and blood products	0.001	0.998	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.001	0.998	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.001	0.998	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.001	0.998	0.000
Y48.4 Anaesthetic, unspecified	0.001	0.998	0.000
S72.10 Pertrochanteric fracture (closed)	0.002	0.998	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.001	0.998	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.001	0.998	0.000
Y53.7 Emetics	0.001	0.998	0.000
Y53.6 Antidiarrhoeal drugs	0.001	0.998	0.000
Y53.5 Digestants	0.001	0.998	0.000
Y53.3 Saline and osmotic laxatives	0.001	0.998	0.000
Y53.2 Stimulant laxatives	0.001	0.998	0.000
Y53.0 Histamine H2-receptor antagonists	0.001	0.998	0.000
S80.0 Contusion of knee	0.000	0.998	0.002
Y53.1 Other antacids and anti-gastric-secretion drugs	0.001	0.998	0.000
Y56.9 Topical agent, unspecified	0.001	0.998	0.000
Y56.8 Other topical agents	0.001	0.998	0.000
Y56.7 Dental drugs, topically applied	0.001	0.998	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.001	0.998	0.000
Y56.5 Ophthalmological drugs and preparations	0.001	0.998	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.001	0.998	0.000
Y56.3 Emollients, demulcents and protectants	0.001	0.998	0.000
Y56.2 Local astringents and local detergents	0.001	0.998	0.000
Y56.1 Antipruritics	0.001	0.998	0.000
F99 Mental disorder, not otherwise specified	0.000	0.998	0.002
Y49.9 Psychotropic drug, unspecified	0.001	0.998	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.001	0.998	0.000
Y49.7 Psychostimulants with abuse potential	0.001	0.998	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.001	0.998	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.001	0.998	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.001	0.998	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.001	0.998	0.000
K09.1 Developmental (nonodontogenic) cysts of oral region	0.000	0.998	0.001
K63.8 Other specified diseases of intestine	0.002	0.998	0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.001	0.998	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.001	0.998	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.999	0.001
G61.0 Guillain-Barre syndrome	0.000	0.999	0.001
H33.2 Serous retinal detachment	0.000	0.999	0.001
I24.1 Dressler's syndrome	0.000	0.999	0.001
R40.2 Coma, unspecified	0.001	0.999	0.000
T86.8 Failure and rejection of other transplanted organs and tissues	0.000	0.999	0.001
S72.9 Fracture of femur, part unspecified	0.001	0.999	0.000
S72.7 Multiple fractures of femur	0.001	0.999	0.000
S72.4 Fracture of lower end of femur	0.001	0.999	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.001	0.999	0.000
K09.9 Cyst of oral region, unspecified	0.000	0.999	0.001
Y48.3 Local anaesthetics	0.001	0.999	0.000
G12.2 Motor neuron disease	0.001	0.999	0.000
O75.8 Other specified complications of labour and delivery	0.001	0.999	0.000
Y53.4 Other laxatives	0.001	0.999	0.000
S72.11 Pertrochanteric fracture (open)	0.001	0.999	0.000
S72.8 Fractures of other parts of femur	0.001	0.999	0.000
Y49.2 Other and unspecified antidepressants	0.001	0.999	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.001	0.999	0.000
Y57.5 X-ray contrast media	0.000	0.999	0.001
Y52 Agents primarily affecting the cardiovascular system	0.001	0.999	0.000
K50.9 Crohn's disease, unspecified	0.001	0.999	0.000
M20.2 Hallux rigidus	0.001	0.999	0.000
O75.5 Delayed delivery after artificial rupture of membranes	0.001	0.999	0.000
S01.2 Open wound of nose	0.001	0.999	0.000
S72.2 Subtrochanteric fracture	0.001	0.999	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.001	0.999	0.000
G24.9 Dystonia, unspecified	0.000	0.999	0.001
S62.50 Fracture of thumb (closed)	0.000	0.999	0.001
O86.0 Infection of obstetric surgical wound	0.001	0.999	0.000
X68.9 Unspecified place	0.001	0.999	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.001	0.999	0.000
K11.5 Sialolithiasis	0.000	0.999	0.001
O75.0 Maternal distress during labour and delivery	0.001	0.999	0.000
X67.9 Unspecified place	0.001	0.999	0.000
Y42.7 Androgens and anabolic congeners	0.001	0.999	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.001	0.999	0.000
M66.06 Rupture of popliteal cyst-Lower leg	0.001	0.999	0.000
M81.4 Drug-induced osteoporosis	0.001	0.999	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.001	0.999	0.000
X62.0 Home	0.001	0.999	0.000
X62.8 Other specified place	0.001	0.999	0.000
X62.7 Farm	0.001	0.999	0.000
X62.6 Industrial and construction area	0.001	0.999	0.000
X62.5 Trade and service area	0.001	0.999	0.000
X62.4 Street and highway	0.001	0.999	0.000
X62.3 Sports and athletics area	0.001	0.999	0.000
X62.2 School, other institution and public administrative area	0.001	0.999	0.000
X62.1 Residential institution	0.001	0.999	0.000
Y54.9 Mineral salts, not elsewhere classified	0.001	0.999	0.000
Y54.8 Agents affecting uric acid metabolism	0.001	0.999	0.000
Y54.7 Agents affecting calcification	0.001	0.999	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.001	0.999	0.000
Y54.5 Other diuretics	0.001	0.999	0.000
Y54.4 Loop [high-ceiling] diuretics	0.001	0.999	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.001	0.999	0.000
Y54.0 Mineralocorticoids	0.001	0.999	0.000
S22.20 Fracture of sternum (closed)	0.000	0.999	0.001
S72.71 Multiple fractures of femur (open)	0.001	0.999	0.000
S72.70 Multiple fractures of femur (closed)	0.001	0.999	0.000
S72.91 Fracture of femur, part unspecified (open)	0.001	0.999	0.000
S72.90 Fracture of femur, part unspecified (closed)	0.001	0.999	0.000
S72.3 Fracture of shaft of femur	0.001	0.999	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.001	0.999	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.001	0.999	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.001	0.999	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.001	0.999	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.001	0.999	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.001	0.999	0.000
Y51.0 Anticholinesterase agents	0.001	0.999	0.000
S72.40 Fracture of lower end of femur (closed)	0.001	0.999	0.000
D41.0 Kidney	0.001	0.999	0.000
S01.3 Open wound of ear	0.001	0.999	0.000
K50 Crohn's disease [regional enteritis]	0.001	0.999	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
M81.49 Drug-induced osteoporosis (Site unspecified)	0.001	0.999	0.000
S72.41 Fracture of lower end of femur (open)	0.001	0.999	0.000
S72.81 Fractures of other parts of femur (open)	0.001	0.999	0.000
D47.2 Monoclonal gammopathy	0.000	0.999	0.001
K50.8 Other Crohn's disease	0.001	0.999	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.001	0.999	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.001	0.999	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.001	0.999	0.000
Y52.7 Peripheral vasodilators	0.001	0.999	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.001	0.999	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.001	0.999	0.000
Z03.9 Observation for suspected disease or condition, unspecified	0.000	0.999	0.001
Y57 Other and unspecified drugs and medicaments	0.001	0.999	0.000
M19.90 Arthrosis, unspecified (Multiple sites)	0.000	0.999	0.001
S72.21 Subtrochanteric fracture (open)	0.001	0.999	0.000
B50.9 Plasmodium falciparum malaria, unspecified	0.001	0.999	0.000
D35.1 Parathyroid gland	0.000	0.999	0.001
F41.1 Generalised anxiety disorder	0.001	0.999	0.000
Q18.0 Sinus, fistula and cyst of branchial cleft	0.001	0.999	0.000
S66.8 Injury of other muscles and tendons at wrist and hand level	0.000	0.999	0.001
S80.8 Other superficial injuries of lower leg	0.000	0.999	0.001
X69.9 Unspecified place	0.001	0.999	0.000
Y49.5 Other antipsychotics and neuroleptics	0.001	0.999	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.001	0.999	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.001	0.999	0.000
O86 Other puerperal infections	0.001	0.999	0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.999	0.001
X62.09 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified: Home: During unspecified activity	0.001	0.999	0.000
H11.1 Conjunctival degenerations and deposits	0.000	0.999	0.001
Q54.9 Hypospadias, unspecified	0.000	0.999	0.001
Z52.4 Kidney donor	0.001	0.999	0.000
M81.48 Drug-induced osteoporosis (Other)	0.001	0.999	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.001	0.999	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.001	0.999	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.001	0.999	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations