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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs13272568
log Bayes Factor = <0.0001
Chromosome 8   position 79,034,459  (GRCh37) Explore rs13272568 on Ensembl!
Variant rs13272568 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Y40.0 Penicillins
0.063 0.937 0.000
R53 Malaise and fatigue
0.063 0.937 0.000
Y40 Systemic antibiotics
0.058 0.942 0.000
Y52 Agents primarily affecting the cardiovascular system
0.056 0.944 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.054 0.946 0.000
Y40.8 Other systemic antibiotics
0.053 0.947 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.051 0.949 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.051 0.949 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.050 0.950 0.000
Y40.1 Cefalosporins and other -lactam antibiotics
0.049 0.951 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.045 0.955 0.000
Y43 Primarily systemic agents
0.045 0.955 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.044 0.956 0.000
Y43.4 Immunosuppressive agents
0.044 0.956 0.000
Y40.6 Rifamycins
0.043 0.956 0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action
0.043 0.957 0.000
Y40.5 Aminoglycosides
0.042 0.957 0.000
Y40.4 Tetracyclines
0.042 0.958 0.000
Y40.7 Antifungal antibiotics, systemically used
0.042 0.958 0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system
0.042 0.958 0.000
Y40.2 Chloramphenicol group
0.042 0.958 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.042 0.958 0.000
Y52.7 Peripheral vasodilators
0.041 0.959 0.000
Y58 Bacterial vaccines
0.040 0.960 0.000
Y52.8 Antivaricose drugs, including sclerosing agents
0.040 0.960 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.040 0.960 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.039 0.961 0.000
Y43.0 Antiallergic and antiemetic drugs
0.038 0.962 0.000
R27.0 Ataxia, unspecified
0.038 0.962 0.000
Y59 Other and unspecified vaccines and biological substances
0.038 0.962 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.037 0.963 0.000
Y46.2 Hydantoin derivatives
0.037 0.963 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.037 0.963 0.000
Y46.6 Other and unspecified antiepileptics
0.037 0.963 0.000
Y56.3 Emollients, demulcents and protectants
0.036 0.964 0.000
Y45.2 Propionic acid derivatives
0.036 0.964 0.000
Y46.4 Iminostilbenes
0.036 0.964 0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.035 0.965 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.035 0.965 0.000
Y48 Anaesthetics and therapeutic gases
0.034 0.965 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.033 0.967 0.000
Y46.8 Antispasticity drugs
0.033 0.967 0.000
Y46.5 Valproic acid
0.033 0.967 0.000
Y46.3 Deoxybarbiturates
0.033 0.967 0.000
Y46.1 Oxazolidinediones
0.033 0.967 0.000
Y46.0 Succinimides
0.033 0.967 0.000
Y46.7 Anti-Parkinsonism drugs
0.033 0.967 0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.033 0.967 0.000
Y58.0 BCG vaccine
0.033 0.967 0.000
Y43.9 Primarily systemic agent, unspecified
0.032 0.967 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.032 0.967 0.000
Y43.6 Enzymes, not elsewhere classified
0.032 0.967 0.000
Y43.5 Acidifying and alkalising agents
0.032 0.967 0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.032 0.968 0.000
Y56.9 Topical agent, unspecified
0.032 0.968 0.000
Y56.8 Other topical agents
0.032 0.968 0.000
Y56.7 Dental drugs, topically applied
0.032 0.968 0.000
Y56.6 Otorhinolaryngological drugs and preparations
0.032 0.968 0.000
Y56.5 Ophthalmological drugs and preparations
0.032 0.968 0.000
Y56.2 Local astringents and local detergents
0.032 0.968 0.000
Y56.1 Antipruritics
0.032 0.968 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.031 0.969 0.000
Y44 Agents primarily affecting blood constituents
0.031 0.969 0.000
Y43.1 Antineoplastic antimetabolites
0.031 0.969 0.000
Y43.2 Antineoplastic natural products
0.030 0.969 0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]
0.030 0.970 0.000
Y55.6 Antiasthmatics, not elsewhere classified
0.030 0.970 0.000
Y52.1 Calcium-channel blockers
0.030 0.970 0.000
Y50.2 Methylxanthines, not elsewhere classified
0.030 0.970 0.000
Y59.3 Immunoglobulin
0.030 0.970 0.000
Y55.4 Expectorants
0.030 0.970 0.000
Y55.0 Oxytocic drugs
0.029 0.971 0.000
Y58.9 Other and unspecified bacterial vaccines
0.029 0.971 0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component
0.029 0.971 0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component
0.029 0.971 0.000
Y58.5 Diphtheria vaccine
0.029 0.971 0.000
Y58.4 Tetanus vaccine
0.029 0.971 0.000
Y58.3 Plague vaccine
0.029 0.971 0.000
Y58.2 Cholera vaccine
0.029 0.971 0.000
Y58.1 Typhoid and paratyphoid vaccine
0.029 0.971 0.000
Y49.0 Tricyclic and tetracyclic antidepressants
0.029 0.971 0.000
Y45.5 4-Aminophenol derivatives
0.029 0.971 0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system
0.029 0.971 0.000
Y55.5 Anticommon cold drugs
0.029 0.971 0.000
Y55.3 Antitussives
0.029 0.971 0.000
Y55.2 Other and unspecified agents primarily acting on muscles
0.029 0.971 0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.029 0.971 0.000
Y50.9 Central nervous system stimulant, unspecified
0.028 0.972 0.000
Y50.8 Other central nervous system stimulants
0.028 0.972 0.000
Y50.1 Opioid receptor antagonists
0.028 0.972 0.000
Y50.0 Analeptics
0.028 0.972 0.000
Y57 Other and unspecified drugs and medicaments
0.028 0.972 0.000
Y59.9 Vaccine or biological substance, unspecified
0.027 0.973 0.000
Y59.8 Other specified vaccines and biological substances
0.027 0.973 0.000
Y59.2 Protozoal vaccines
0.027 0.973 0.000
Y59.1 Rickettsial vaccines
0.027 0.973 0.000
Y45.4 Antirheumatics
0.027 0.973 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.027 0.973 0.000
Y40.9 Systemic antibiotic, unspecified
0.027 0.973 0.000
Y49.9 Psychotropic drug, unspecified
0.027 0.973 0.000
Y49.8 Other psychotropic drugs, not elsewhere classified
0.027 0.973 0.000
Y49.7 Psychostimulants with abuse potential
0.027 0.973 0.000
Y49.6 Psychodysleptics [hallucinogens]
0.027 0.973 0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics
0.027 0.973 0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics
0.027 0.973 0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants
0.027 0.973 0.000
Y40.3 Macrolides
0.026 0.973 0.000
Y49.5 Other antipsychotics and neuroleptics
0.026 0.974 0.000
Y48.4 Anaesthetic, unspecified
0.025 0.975 0.000
Y45.8 Other analgesics and antipyretics
0.025 0.975 0.000
Y48.2 Other and unspecified general anaesthetics
0.025 0.975 0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified
0.025 0.975 0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs
0.025 0.975 0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified
0.025 0.975 0.000
Y47.4 Bromine compounds
0.025 0.975 0.000
Y47.3 Paraldehyde
0.025 0.975 0.000
Y47.2 Chloral derivatives
0.025 0.975 0.000
Y47.0 Barbiturates, not elsewhere classified
0.025 0.975 0.000
Y48.5 Therapeutic gases
0.025 0.975 0.000
Y48.1 Parenteral anaesthetics
0.025 0.975 0.000
Y48.0 Inhaled anaesthetics
0.025 0.975 0.000
Y59.0 Viral vaccines
0.024 0.975 0.000
Y54.5 Other diuretics
0.024 0.976 0.000
Y49.2 Other and unspecified antidepressants
0.024 0.976 0.000
Y45.0 Opioids and related analgesics
0.024 0.976 0.000
Y54.9 Mineral salts, not elsewhere classified
0.024 0.976 0.000
Y54.6 Electrolytic, caloric and water-balance agents
0.024 0.976 0.000
Y54.2 Carbonic-anhydrase inhibitors
0.024 0.976 0.000
Y54.0 Mineralocorticoids
0.024 0.976 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.024 0.976 0.000
Y44.6 Natural blood and blood products
0.024 0.976 0.000
Y53.4 Other laxatives
0.023 0.976 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.023 0.977 0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]
0.023 0.977 0.000
Y53.2 Stimulant laxatives
0.023 0.977 0.000
Y41.5 Antiviral drugs
0.023 0.977 0.000
Y47.1 Benzodiazepines
0.022 0.977 0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.022 0.977 0.000
Y53.7 Emetics
0.022 0.977 0.000
Y53.6 Antidiarrhoeal drugs
0.022 0.977 0.000
Y53.5 Digestants
0.022 0.977 0.000
Y53.3 Saline and osmotic laxatives
0.022 0.977 0.000
Y53.0 Histamine H2-receptor antagonists
0.022 0.977 0.000
Y44.9 Other and unspecified agents affecting blood constituents
0.022 0.978 0.000
Y44.7 Plasma substitutes
0.022 0.978 0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations
0.022 0.978 0.000
Y54.4 Loop [high-ceiling] diuretics
0.022 0.978 0.000
Y44.5 Thrombolytic drugs
0.021 0.978 0.000
Y48.3 Local anaesthetics
0.021 0.979 0.000
Y54.7 Agents affecting calcification
0.021 0.979 0.000
Y54.8 Agents affecting uric acid metabolism
0.021 0.979 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.021 0.979 0.000
Y44.2 Anticoagulants
0.021 0.979 0.000
Y57.7 Vitamins, not elsewhere classified
0.020 0.980 0.000
Y57.4 Pharmaceutical excipients
0.020 0.980 0.000
Y57.3 Alcohol deterrents
0.020 0.980 0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified
0.020 0.980 0.000
Y57.1 Lipotropic drugs
0.020 0.980 0.000
Y57.0 Appetite depressants [anorectics]
0.020 0.980 0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system
0.020 0.980 0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations
0.020 0.980 0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants
0.020 0.980 0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified
0.019 0.980 0.000
Y41.4 Anthelminthics
0.019 0.980 0.000
Y41.3 Other antiprotozoal drugs
0.019 0.980 0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa
0.019 0.980 0.000
Y57.6 Other diagnostic agents
0.019 0.981 0.000
Y41.1 Antimycobacterial drugs
0.019 0.981 0.000
Y57.5 X-ray contrast media
0.019 0.981 0.000
Y57.9 Drug or medicament, unspecified
0.018 0.982 0.000
Y53.1 Other antacids and anti-gastric-secretion drugs
0.017 0.983 0.000
N28.1 Cyst of kidney, acquired
0.017 0.983 0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system
0.017 0.983 0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified
0.017 0.983 0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.017 0.983 0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified
0.017 0.983 0.000
Y51.1 Other parasympathomimetics [cholinergics]
0.017 0.983 0.000
Y51.0 Anticholinesterase agents
0.017 0.983 0.000
Y45.1 Salicylates
0.016 0.983 0.000
Y57.8 Other drugs and medicaments
0.016 0.984 0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.016 0.984 0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified
0.016 0.984 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.015 0.985 0.000
Y54.3 Benzothiadiazine derivatives
0.014 0.986 0.000
Y41.0 Sulphonamides
0.014 0.986 0.000
K51.9 Ulcerative colitis, unspecified
0.014 0.986 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.013 0.987 0.000
K51 Ulcerative colitis
0.013 0.987 0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified
0.013 0.987 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.013 0.987 0.000
K51.2 Ulcerative (chronic) proctitis
0.012 0.988 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.000 0.988 0.012
C92.1 Chronic myeloid leukaemia
0.000 0.988 0.012
T43.2 Other and unspecified antidepressants
0.000 0.989 0.011
Y42.9 Other and unspecified hormone antagonists
0.011 0.989 0.000
R27 Other lack of coordination
0.011 0.989 0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.010 0.989 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.011 0.989 0.000
K51.4 Pseudopolyposis of colon
0.010 0.990 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.000 0.990 0.010
Y42.1 Thyroid hormones and substitutes
0.010 0.990 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.010 0.990 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.000 0.990 0.010
K52.1 Toxic gastro-enteritis and colitis
0.009 0.991 0.000
Y42.2 Antithyroid drugs
0.009 0.991 0.000
Y42.4 Oral contraceptives
0.009 0.991 0.000
N75.0 Cyst of Bartholin's gland
0.000 0.991 0.009
K51.5 Mucosal proctocolitis
0.009 0.991 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.008 0.992 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.000 0.992 0.008
K51.0 Ulcerative (chronic) enterocolitis
0.008 0.992 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.000 0.992 0.008
T43.9 Psychotropic drug, unspecified
0.000 0.992 0.008
S22.20 Fracture of sternum (closed)
0.000 0.992 0.008
K51.8 Other ulcerative colitis
0.008 0.992 0.000
S22.40 Multiple fractures of ribs (closed)
0.000 0.993 0.007
Y42.5 Other oestrogens and progestogens
0.007 0.993 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.007 0.993 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.000 0.993 0.007
T43.6 Psychostimulants with abuse potential
0.000 0.993 0.007
N75 Diseases of Bartholin's gland
0.000 0.993 0.007
N75.1 Abscess of Bartholin's gland
0.000 0.993 0.007
S22.2 Fracture of sternum
0.000 0.993 0.006
R70.0 Elevated erythrocyte sedimentation rate
0.006 0.993 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.006 0.994 0.000
J39.8 Other specified diseases of upper respiratory tract
0.006 0.994 0.000
S22.4 Multiple fractures of ribs
0.000 0.994 0.006
T86.1 Kidney transplant failure and rejection
0.006 0.994 0.000
Y43.3 Other antineoplastic drugs
0.006 0.994 0.000
S22.10 Multiple fractures of thoracic spine (closed)
0.000 0.994 0.006
S22 Fracture of rib(s), sternum and thoracic spine
0.000 0.994 0.006
S22.1 Multiple fractures of thoracic spine
0.000 0.994 0.006
R27.8 Other and unspecified lack of coordination
0.005 0.994 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.000 0.994 0.006
Q21.1 Atrial septal defect
0.006 0.994 0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified
0.005 0.995 0.000
N75.8 Other diseases of Bartholin's gland
0.000 0.995 0.005
Q24 Other congenital malformations of heart
0.005 0.995 0.000
Q27 Other congenital malformations of peripheral vascular system
0.005 0.995 0.000
Q21 Congenital malformations of cardiac septa
0.005 0.995 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.005 0.995 0.000
K50-K52 Noninfective enteritis and colitis
0.005 0.995 0.000
N75.9 Disease of Bartholin's gland, unspecified
0.000 0.995 0.005
K52 Other non-infective gastro-enteritis and colitis
0.005 0.995 0.000
S22.21 Fracture of sternum (open)
0.000 0.995 0.005
S22.41 Multiple fractures of ribs (open)
0.000 0.995 0.005
Q21.8 Other congenital malformations of cardiac septa
0.005 0.995 0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.005 0.995 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.000 0.995 0.005
T46.4 Angiotensin-converting-enzyme inhibitors
0.000 0.995 0.005
Q24.9 Congenital malformation of the heart, unspecified
0.005 0.995 0.000
Q25 Congenital malformations of great arteries
0.005 0.995 0.000
Q24.6 Congenital heart block
0.005 0.995 0.000
Y42.7 Androgens and anabolic congeners
0.004 0.995 0.000
S22.0 Fracture of thoracic vertebra
0.000 0.995 0.004
Q24.0 Dextrocardia
0.004 0.996 0.000
Q28 Other congenital malformations of circulatory system
0.004 0.996 0.000
Q24.8 Other specified congenital malformations of heart
0.004 0.996 0.000
Q24.5 Malformation of coronary vessels
0.004 0.996 0.000
Q27.3 Peripheral arteriovenous malformation
0.004 0.996 0.000
S22.9 Fracture of bony thorax, part unspecified
0.000 0.996 0.004
S22.8 Fracture of other parts of bony thorax
0.000 0.996 0.004
S22.11 Multiple fractures of thoracic spine (open)
0.000 0.996 0.004
T46 Poisoning by agents primarily affecting the cardiovascular system
0.000 0.996 0.004
Q24.4 Congenital subaortic stenosis
0.004 0.996 0.000
Q24.3 Pulmonary infundibular stenosis
0.004 0.996 0.000
Q24.2 Cor triatriatum
0.004 0.996 0.000
Q24.1 Levocardia
0.004 0.996 0.000
Q25.0 Patent ductus arteriosus
0.004 0.996 0.000
Q21.4 Aortopulmonary septal defect
0.004 0.996 0.000
Q21.2 Atrioventricular septal defect
0.004 0.996 0.000
Q27.4 Congenital phlebectasia
0.004 0.996 0.000
Q27.2 Other congenital malformations of renal artery
0.004 0.996 0.000
Q27.1 Congenital renal artery stenosis
0.004 0.996 0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery
0.004 0.996 0.000
Q26 Congenital malformations of great veins
0.004 0.996 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.004 0.996 0.000
T38.1 Thyroid hormones and substitutes
0.000 0.996 0.004
K60.2 Anal fissure, unspecified
0.004 0.996 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.000 0.996 0.004
Y79.2 Prosthetic and other implants, materials and accessory devices
0.004 0.996 0.000
Q21.9 Congenital malformation of cardiac septum, unspecified
0.004 0.996 0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.004 0.996 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.004 0.996 0.000
Q25.3 Stenosis of aorta
0.004 0.996 0.000
Q27.8 Other specified congenital malformations of peripheral vascular system
0.004 0.996 0.000
Q28.2 Arteriovenous malformation of cerebral vessels
0.004 0.996 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.000 0.996 0.004
Q22 Congenital malformations of pulmonary and tricuspid valves
0.004 0.996 0.000
Q23 Congenital malformations of aortic and mitral valves
0.004 0.996 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.000 0.996 0.004
S22.5 Flail chest
0.000 0.996 0.004
Q21.3 Tetralogy of Fallot
0.003 0.996 0.000
T38.9 Other and unspecified hormone antagonists
0.000 0.996 0.003
T38.7 Androgens and anabolic congeners
0.000 0.996 0.003
T38.5 Other oestrogens and progestogens
0.000 0.996 0.003
T38.4 Oral contraceptives
0.000 0.996 0.003
T38.2 Antithyroid drugs
0.000 0.996 0.003
C92 Myeloid leukaemia
0.000 0.996 0.004
K52.3 Indeterminate colitis
0.004 0.996 0.000
Q21.0 Ventricular septal defect
0.004 0.996 0.000
S22.00 Fracture of thoracic vertebra (closed)
0.000 0.996 0.004
Q25.9 Congenital malformation of great arteries, unspecified
0.003 0.996 0.000
Q25.8 Other congenital malformations of great arteries
0.003 0.996 0.000
Q25.5 Atresia of pulmonary artery
0.003 0.996 0.000
Q25.2 Atresia of aorta
0.003 0.996 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.004 0.996 0.000
Q28.3 Other malformations of cerebral vessels
0.003 0.996 0.000
Q25.1 Coarctation of aorta
0.003 0.996 0.000
Q25.7 Other congenital malformations of pulmonary artery
0.003 0.996 0.000
S22.01 Fracture of thoracic vertebra (open)
0.000 0.996 0.003
Q28.9 Congenital malformation of circulatory system, unspecified
0.003 0.997 0.000
Q28.8 Other specified congenital malformations of circulatory system
0.003 0.997 0.000
Q28.1 Other malformations of precerebral vessels
0.003 0.997 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.000 0.997 0.003
Q25.4 Other congenital malformations of aorta
0.003 0.997 0.000
Z39.0 Care and examination immediately after delivery
0.003 0.997 0.000
S22.81 Fracture of other parts of bony thorax (open)
0.000 0.997 0.003
S22.80 Fracture of other parts of bony thorax (closed)
0.000 0.997 0.003
S22.91 Fracture of bony thorax, part unspecified (open)
0.000 0.997 0.003
S22.90 Fracture of bony thorax, part unspecified (closed)
0.000 0.997 0.003
T38.8 Other and unspecified hormones and their synthetic substitutes
0.000 0.997 0.003
J46 Status asthmaticus
0.000 0.997 0.003
C92.7 Other myeloid leukaemia
0.000 0.997 0.003
Q25.6 Stenosis of pulmonary artery
0.003 0.997 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.000 0.997 0.003
T46.8 Antivaricose drugs, including sclerosing agents
0.000 0.997 0.003
T46.7 Peripheral vasodilators
0.000 0.997 0.003
T46.3 Coronary vasodilators, not elsewhere classified
0.000 0.997 0.003
R70.1 Abnormal plasma viscosity
0.003 0.997 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.000 0.997 0.003
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified
0.003 0.997 0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions
0.003 0.997 0.000
Q20.6 Isomerism of atrial appendages
0.003 0.997 0.000
Q20.5 Discordant atrioventricular connexion
0.003 0.997 0.000
Q20.4 Double inlet ventricle
0.003 0.997 0.000
Q20.3 Discordant ventriculoarterial connexion
0.003 0.997 0.000
Q20.2 Double outlet left ventricle
0.003 0.997 0.000
Q20.1 Double outlet right ventricle
0.003 0.997 0.000
Q20.0 Common arterial trunk
0.003 0.997 0.000
Q26.9 Congenital malformation of great vein, unspecified
0.003 0.997 0.000
Q26.8 Other congenital malformations of great veins
0.003 0.997 0.000
Q26.6 Portal vein-hepatic artery fistula
0.003 0.997 0.000
Q26.5 Anomalous portal venous connexion
0.003 0.997 0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified
0.003 0.997 0.000
Q26.3 Partial anomalous pulmonary venous connexion
0.003 0.997 0.000
Q26.2 Total anomalous pulmonary venous connexion
0.003 0.997 0.000
Q26.1 Persistent left superior vena cava
0.003 0.997 0.000
Q26.0 Congenital stenosis of vena cava
0.003 0.997 0.000
Q28.0 Arteriovenous malformation of precerebral vessels
0.003 0.997 0.000
T38.0 Glucocorticoids and synthetic analogues
0.000 0.997 0.003
Q50.4 Embryonic cyst of Fallopian tube
0.000 0.997 0.003
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.000 0.997 0.003
S42.10 Fracture of scapula (closed)
0.000 0.997 0.003
K59.3 Megacolon, not elsewhere classified
0.003 0.997 0.000
Q23.3 Congenital mitral insufficiency
0.003 0.997 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.000 0.997 0.003
T41 Poisoning by anaesthetics and therapeutic gases
0.000 0.997 0.003
Q22.9 Congenital malformation of tricuspid valve, unspecified
0.003 0.997 0.000
Q22.8 Other congenital malformations of tricuspid valve
0.003 0.997 0.000
Q22.6 Hypoplastic right heart syndrome
0.003 0.997 0.000
Q22.4 Congenital tricuspid stenosis
0.003 0.997 0.000
Q22.3 Other congenital malformations of pulmonary valve
0.003 0.997 0.000
Q22.2 Congenital pulmonary valve insufficiency
0.003 0.997 0.000
Q22.0 Pulmonary valve atresia
0.003 0.997 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.000 0.997 0.003
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.000 0.997 0.003
Q22.5 Ebstein's anomaly
0.003 0.997 0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified
0.003 0.997 0.000
Q23.8 Other congenital malformations of aortic and mitral valves
0.003 0.997 0.000
Q23.4 Hypoplastic left heart syndrome
0.003 0.997 0.000
Q23.2 Congenital mitral stenosis
0.003 0.997 0.000
K61.0 Anal abscess
0.000 0.997 0.003
S22.51 Flail chest (open)
0.000 0.997 0.003
S22.3 Fracture of rib
0.000 0.997 0.003
K52.0 Gastro-enteritis and colitis due to radiation
0.003 0.997 0.000
Q23.1 Congenital insufficiency of aortic valve
0.003 0.997 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.000 0.997 0.003
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.000 0.997 0.003
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.000 0.997 0.003
C92.5 Acute myelomonocytic leukaemia
0.000 0.997 0.003
C92.3 Myeloid sarcoma
0.000 0.997 0.003
C92.2 Subacute myeloid leukaemia
0.000 0.997 0.003
G44.0 Cluster headache syndrome
0.003 0.997 0.000
T46.1 Calcium-channel blockers
0.000 0.997 0.003
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.000 0.997 0.003
C92.4 Acute promyelocytic leukaemia
0.000 0.997 0.003
K52.8 Other specified non-infective gastro-enteritis and colitis
0.003 0.997 0.000
Q22.1 Congenital pulmonary valve stenosis
0.003 0.997 0.000
C90.2 Plasmacytoma, extramedullary
0.000 0.997 0.003
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.000 0.997 0.003
T36 Poisoning by systemic antibiotics
0.000 0.997 0.003
G44.8 Other specified headache syndromes
0.003 0.997 0.000
K70.1 Alcoholic hepatitis
0.003 0.997 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.000 0.997 0.002
S02.60 Fracture of mandible (closed)
0.003 0.997 0.000
N18.9 Chronic renal failure, unspecified
0.003 0.997 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.000 0.997 0.003
T86 Failure and rejection of transplanted organs and tissues
0.003 0.997 0.000
G95.9 Disease of spinal cord, unspecified
0.000 0.997 0.003
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.000 0.997 0.002
T86.0 Bone-marrow transplant rejection
0.003 0.997 0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)
0.003 0.997 0.000
M62.80 Other specified disorders of muscle (Multiple sites)
0.003 0.997 0.000
T45.2 Vitamins, not elsewhere classified
0.000 0.997 0.003
G50.0 Trigeminal neuralgia
0.003 0.997 0.000
L29.0 Pruritus ani
0.003 0.997 0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm
0.003 0.997 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.000 0.997 0.003
Q23.0 Congenital stenosis of aortic valve
0.002 0.997 0.000
Z90.0 Acquired absence of part of head and neck
0.000 0.997 0.003
T42.4 Benzodiazepines
0.000 0.997 0.003
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.000 0.997 0.002
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.000 0.997 0.002
Y79 Orthopaedic devices associated with adverse incidents
0.002 0.997 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.000 0.997 0.002
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.000 0.997 0.002
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.000 0.997 0.002
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.000 0.997 0.002
T44.1 Other parasympathomimetics [cholinergics]
0.000 0.997 0.002
T44.0 Anticholinesterase agents
0.000 0.997 0.002
C92.9 Myeloid leukaemia, unspecified
0.000 0.997 0.002
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.000 0.997 0.002
T42.1 Iminostilbenes
0.000 0.997 0.002
T41.5 Therapeutic gases
0.000 0.998 0.002
T41.4 Anaesthetic, unspecified
0.000 0.998 0.002
T41.3 Local anaesthetics
0.000 0.998 0.002
T41.2 Other and unspecified general anaesthetics
0.000 0.998 0.002
T41.1 Intravenous anaesthetics
0.000 0.998 0.002
T41.0 Inhaled anaesthetics
0.000 0.998 0.002
T42.5 Mixed antiepileptics, not elsewhere classified
0.000 0.998 0.002
T42.3 Barbiturates
0.000 0.998 0.002
T42.2 Succinimides and oxazolidinediones
0.000 0.998 0.002
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.000 0.998 0.002
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.000 0.998 0.002
T47.8 Other agents primarily affecting the gastro-intestinal system
0.000 0.998 0.002
T47.7 Emetics
0.000 0.998 0.002
T47.5 Digestants
0.000 0.998 0.002
T47.4 Other laxatives
0.000 0.998 0.002
T47.3 Saline and osmotic laxatives
0.000 0.998 0.002
T47.2 Stimulant laxatives
0.000 0.998 0.002
T47.0 Histamine H(2)-receptor antagonists
0.000 0.998 0.002
S22.31 Fracture of rib (open)
0.000 0.998 0.002
E87.7 Fluid overload
0.002 0.998 0.000
H04.2 Epiphora
0.000 0.998 0.002
T47.6 Antidiarrhoeal drugs
0.000 0.998 0.002
S32.70 Multiple fractures of lumbar spine and pelvis (closed)
0.000 0.998 0.002
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.000 0.998 0.002
T37.5 Antiviral drugs
0.000 0.998 0.002
T37.4 Anthelminthics
0.000 0.998 0.002
T37.3 Other antiprotozoal drugs
0.000 0.998 0.002
T37.2 Antimalarials and drugs acting on other blood protozoa
0.000 0.998 0.002
T37.1 Antimycobacterial drugs
0.000 0.998 0.002
T37.0 Sulphonamides
0.000 0.998 0.002
T47.1 Other antacids and anti-gastric-secretion drugs
0.000 0.998 0.002
T48.5 Anti-common-cold drugs
0.000 0.998 0.002
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.000 0.998 0.002
T48.4 Expectorants
0.000 0.998 0.002
T48.3 Antitussives
0.000 0.998 0.002
T48.2 Other and unspecified agents primarily acting on muscles
0.000 0.998 0.002
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.000 0.998 0.002
T48.0 Oxytocic drugs
0.000 0.998 0.002
T86.9 Failure and rejection of unspecified transplanted organ and tissue
0.002 0.998 0.000
T36.3 Macrolides
0.000 0.998 0.002
S22.50 Flail chest (closed)
0.000 0.998 0.002
T36.9 Systemic antibiotic, unspecified
0.000 0.998 0.002
T36.8 Other systemic antibiotics
0.000 0.998 0.002
T36.7 Antifungal antibiotics, systemically used
0.000 0.998 0.002
T36.6 Rifamycins
0.000 0.998 0.002
T36.5 Aminoglycosides
0.000 0.998 0.002
T36.4 Tetracyclines
0.000 0.998 0.002
T36.2 Chloramphenicol group
0.000 0.998 0.002
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.000 0.998 0.002
I98.2 Oesophageal varices in diseases classified elsewhere
0.002 0.998 0.000
T86.4 Liver transplant failure and rejection
0.002 0.998 0.000
T49.9 Topical agent, unspecified
0.000 0.998 0.002
T49.8 Other topical agents
0.000 0.998 0.002
T49.7 Dental drugs, topically applied
0.000 0.998 0.002
T49.6 Otorhinolaryngological drugs and preparations
0.000 0.998 0.002
T49.5 Ophthalmological drugs and preparations
0.000 0.998 0.002
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.000 0.998 0.002
T49.3 Emollients, demulcents and protectants
0.000 0.998 0.002
T49.2 Local astringents and local detergents
0.000 0.998 0.002
T49.1 Antipruritics
0.000 0.998 0.002
G43.1 Migraine with aura [classical migraine]
0.000 0.998 0.002
T45.9 Primarily systemic and haematological agent, unspecified
0.000 0.998 0.002
T45.8 Other primarily systemic and haematological agents
0.000 0.998 0.002
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.000 0.998 0.002
T45.6 Fibrinolysis-affecting drugs
0.000 0.998 0.002
T45.4 Iron and its compounds
0.000 0.998 0.002
T45.3 Enzymes, not elsewhere classified
0.000 0.998 0.002
T86.3 Heart-lung transplant failure and rejection
0.002 0.998 0.000
T86.2 Heart transplant failure and rejection
0.002 0.998 0.000
T37.8 Other specified systemic anti-infectives and antiparasitics
0.000 0.998 0.002
M62.8 Other specified disorders of muscle
0.002 0.998 0.000
B25.9 Cytomegaloviral disease, unspecified
0.002 0.998 0.000
T94.1 Sequelae of injuries, not specified by body region
0.000 0.998 0.002
Y79.8 Miscellaneous devices, not elsewhere classified
0.002 0.998 0.000
Y79.1 Therapeutic (nonsurgical) and rehabilitative devices
0.002 0.998 0.000
Y79.0 Diagnostic and monitoring devices
0.002 0.998 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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