TreeWAS – Variant ID: rs13277394

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter II Neoplasms	0.999	0.001
Chapter XX External causes of morbidity and mortality	0.999	0.001
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.998	0.002
M50-M54 Other dorsopathies	0.997	0.003
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.996	0.004
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.996	0.004
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.996	0.004
D70-D77 Other diseases of blood and blood-forming organs	0.995	0.005
D70 Agranulocytosis	0.995	0.005
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.994	0.006
Chapter V Mental and behavioural disorders	0.993	0.007
Chapter VII Diseases of the eye and adnexa	0.992	0.008
H53-H54 Visual disturbances and blindness	0.990	0.010
H54 Blindness and low vision	0.982	0.018
C15-C26 Malignant neoplasms of digestive organs	0.980	0.020
F40-F48 Neurotic, stress-related and somatoform disorders	0.975	0.025
Chapter I Certain infectious and parasitic diseases	0.972	0.028
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.971	0.029
H30-H36 Disorders of choroid and retina	0.970	0.030
M54 Dorsalgia	0.968	0.032
C90 Multiple myeloma and malignant plasma cell neoplasms	0.963	0.037
F41 Other anxiety disorders	0.959	0.041
B15-B19 Viral hepatitis	0.954	0.046
F30-F39 Mood [affective] disorders	0.952	0.048
W00-W19 Falls	0.951	0.049
M51 Other intervertebral disk disorders	0.946	0.054
M54.1 Radiculopathy	0.944	0.056
H53 Visual disturbances	0.941	0.059
M50 Cervical disk disorders	0.941	0.059
C18 Malignant neoplasm of colon	0.940	0.060
C90.0 Multiple myeloma	0.934	0.066
Y43 Primarily systemic agents	0.931	0.069
C83 Diffuse non-Hodgkin's lymphoma	0.929	0.071
C19 Malignant neoplasm of rectosigmoid junction	0.926	0.074
F41.9 Anxiety disorder, unspecified	0.923	0.077
B35-B49 Mycoses	0.915	0.085
B18 Chronic viral hepatitis	0.915	0.085
H35 Other retinal disorders	0.911	0.089
W19 Unspecified fall	0.911	0.089
T20-T25 Burns and corrosions of external body surface, specified by site	0.910	0.090
H53.4 Visual field defects	0.908	0.092
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.907	0.093
C18.7 Sigmoid colon	0.906	0.094
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.906	0.094
F41.2 Mixed anxiety and depressive disorder	0.905	0.095
H54.0 Blindness, both eyes	0.903	0.097
D37-D48 Neoplasms of uncertain or unknown behaviour	0.901	0.099
S60-S69 Injuries to the wrist and hand	0.893	0.107
H53.1 Subjective visual disturbances	0.891	0.109
B18.2 Chronic viral hepatitis C	0.887	0.113
C18.2 Ascending colon	0.886	0.114
H54.7 Unspecified visual loss	0.879	0.121
H54.4 Blindness, one eye	0.878	0.122
M91-M94 Chondropathies	0.878	0.122
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.876	0.124
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.876	0.124
Y51 Drugs primarily affecting the autonomic nervous system	0.872	0.128
Y43.3 Other antineoplastic drugs	0.866	0.134
H35.4 Peripheral retinal degeneration	0.864	0.136
M54.16 Radiculopathy (Lumbar region)	0.862	0.138
C84 Peripheral and cutaneous T-cell lymphomas	0.861	0.139
C79 Secondary malignant neoplasm of other sites	0.859	0.141
W19.9 Unspecified place	0.859	0.141
B37 Candidiasis	0.859	0.141
Y57 Other and unspecified drugs and medicaments	0.858	0.142
M51.2 Other specified intervertebral disk displacement	0.849	0.151
W19.2 School, other institution and public administrative area	0.846	0.154
H54.9 Unspecified visual impairment (binocular)	0.846	0.154
H33 Retinal detachments and breaks	0.844	0.156
S80-S89 Injuries to the knee and lower leg	0.843	0.157
F31 Bipolar affective disorder	0.839	0.161
D72 Other disorders of white blood cells	0.837	0.163
M50.3 Other cervical disk degeneration	0.837	0.163
F45 Somatoform disorders	0.837	0.163
M86-M90 Other osteopathies	0.833	0.167
C76 Malignant neoplasm of other and ill-defined sites	0.833	0.167
Y40 Systemic antibiotics	0.832	0.168
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.831	0.169
S50-S59 Injuries to the elbow and forearm	0.830	0.170
M51.9 Intervertebral disk disorder, unspecified	0.830	0.170
C83.3 Large cell (diffuse)	0.830	0.170
S10-S19 Injuries to the neck	0.826	0.174
A30-A49 Other bacterial diseases	0.824	0.176
H34 Retinal vascular occlusions	0.824	0.176
W06 Fall involving bed	0.824	0.176
S90-S99 Injuries to the ankle and foot	0.823	0.177
M50.1 Cervical disk disorder with radiculopathy	0.821	0.179
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.821	0.179
C77.2 Intra-abdominal lymph nodes	0.820	0.180
B37.0 Candidal stomatitis	0.818	0.182
F80-F89 Disorders of psychological development	0.817	0.183
F32 Depressive episode	0.816	0.184
Y44 Agents primarily affecting blood constituents	0.810	0.190
T91 Sequelae of injuries of neck and trunk	0.809	0.191
X58-X59 Accidental exposure to other and unspecified factors	0.808	0.192
C21 Malignant neoplasm of anus and anal canal	0.806	0.194
F33 Recurrent depressive disorder	0.804	0.196
M80-M85 Disorders of bone density and structure	0.804	0.196
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.803	0.197
H18 Other disorders of cornea	0.801	0.199
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.801	0.199
C79.2 Secondary malignant neoplasm of skin	0.801	0.199
B17 Other acute viral hepatitis	0.799	0.200
X50-X57 Overexertion, travel and privation	0.799	0.201
T66-T78 Other and unspecified effects of external causes	0.797	0.203
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.793	0.207
Y53 Agents primarily affecting the gastro-intestinal system	0.789	0.211
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.787	0.213
Chapter VI Diseases of the nervous system	0.786	0.214
S60 Superficial injury of wrist and hand	0.786	0.214
Chapter XXII Codes for special purposes	0.786	0.214
M93 Other osteochondropathies	0.785	0.214
D46 Myelodysplastic syndromes	0.785	0.215
C95 Leukaemia of unspecified cell type	0.785	0.215
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.784	0.216
Y46 Antiepileptics and anti-Parkinsonism drugs	0.783	0.217
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.782	0.218
S40-S49 Injuries to the shoulder and upper arm	0.782	0.218
M54.17 Radiculopathy (Lumbosacral region)	0.779	0.221
C79.8 Secondary malignant neoplasm of other specified sites	0.779	0.221
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.779	0.221
M70-M79 Other soft tissue disorders	0.777	0.223
C77.0 Lymph nodes of head, face and neck	0.777	0.223
F40 Phobic anxiety disorders	0.776	0.224
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.775	0.224
M54.18 Radiculopathy (Sacral and sacrococcygeal region)	0.773	0.226
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.773	0.227
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.772	0.228
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.771	0.229
T93 Sequelae of injuries of lower limb	0.770	0.230
M54.12 Radiculopathy (Cervical region)	0.769	0.231
M54.3 Sciatica	0.766	0.234
C85.1 B-cell lymphoma, unspecified	0.761	0.239
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.760	0.240
B16 Acute hepatitis B	0.759	0.241
Y52 Agents primarily affecting the cardiovascular system	0.756	0.243
F00-F09 Organic, including symptomatic, mental disorders	0.753	0.247
C84.5 Other and unspecified T-cell lymphomas	0.751	0.249
T21 Burn and corrosion of trunk	0.751	0.249
C16 Malignant neoplasm of stomach	0.751	0.249
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.750	0.249
H35.6 Retinal haemorrhage	0.747	0.253
M40-M43 Deforming dorsopathies	0.747	0.253
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.746	0.254
D55-D59 Haemolytic anaemias	0.745	0.255
Y43.1 Antineoplastic antimetabolites	0.745	0.255
Y43.0 Antiallergic and antiemetic drugs	0.744	0.256
M60-M63 Disorders of muscles	0.744	0.256
D50-D53 Nutritional anaemias	0.744	0.256
V10-V19 Pedal cyclist injured in transport accident	0.744	0.256
C90.2 Plasmacytoma, extramedullary	0.744	0.256
C83.1 Small cleaved cell (diffuse)	0.742	0.258
F32.1 Moderate depressive episode	0.742	0.258
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.741	0.259
Chapter IV Endocrine, nutritional and metabolic diseases	0.739	0.261
F45.8 Other somatoform disorders	0.738	0.262
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.737	0.263
H35.0 Background retinopathy and retinal vascular changes	0.737	0.263
H35.8 Other specified retinal disorders	0.734	0.266
W50-W64 Exposure to animate mechanical forces	0.734	0.266
M50.9 Cervical disk disorder, unspecified	0.734	0.266
Y40.0 Penicillins	0.734	0.266
C43-C44 Melanoma and other malignant neoplasms of skin	0.733	0.267
W06.0 Home	0.733	0.267
Chapter IX Diseases of the circulatory system	0.732	0.268
A41 Other septicaemia	0.732	0.268
T25 Burn and corrosion of ankle and foot	0.731	0.269
C88 Malignant immunoproliferative diseases	0.730	0.270
D73 Diseases of spleen	0.730	0.270
B19 Unspecified viral hepatitis	0.729	0.271
H31 Other disorders of choroid	0.729	0.271
H18.5 Hereditary corneal dystrophies	0.728	0.272
G20-G26 Extrapyramidal and movement disorders	0.728	0.272
M54.19 Radiculopathy (Site unspecified)	0.728	0.272
M54.6 Pain in thoracic spine	0.727	0.273
C26 Malignant neoplasm of other and ill-defined digestive organs	0.726	0.273
T00-T07 Injuries involving multiple body regions	0.726	0.274
C80 Malignant neoplasm without specification of site	0.726	0.274
M54.2 Cervicalgia	0.726	0.274
Y49 Psychotropic drugs, not elsewhere classified	0.725	0.274
F41.1 Generalised anxiety disorder	0.725	0.274
B99-B99 Other infectious diseases	0.725	0.275
M51.8 Other specified intervertebral disk disorders	0.725	0.275
D72.8 Other specified disorders of white blood cells	0.724	0.276
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.723	0.276
S65 Injury of blood vessels at wrist and hand level	0.721	0.279
M93.9 Osteochondropathy, unspecified	0.720	0.280
V40-V49 Car occupant injured in transport accident	0.719	0.280
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.719	0.281
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.719	0.281
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
M90 Osteopathies in diseases classified elsewhere	0.716	0.283
B25-B34 Other viral diseases	0.716	0.284
C40-C41 Malignant neoplasms of bone and articular cartilage	0.716	0.284
Y35-Y36 Legal intervention and operations of war	0.716	0.284
Y10-Y34 Event of undetermined intent	0.716	0.284
Y00-Y09 Assault	0.716	0.284
X85-X99 Assault	0.716	0.284
X30-X39 Exposure to forces of nature	0.716	0.284
X10-X19 Contact with heat and hot substances	0.716	0.284
X00-X09 Exposure to smoke, fire and flames	0.716	0.284
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.716	0.284
W75-W84 Other accidental threats to breathing	0.716	0.284
W65-W74 Accidental drowning and submersion	0.716	0.284
V98-V99 Other and unspecified transport accidents	0.716	0.284
V95-V97 Air and space transport accidents	0.716	0.284
V90-V94 Water transport accidents	0.716	0.284
V70-V79 Bus occupant injured in transport accident	0.716	0.284
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.716	0.284
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.716	0.284
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.716	0.284
V01-V09 Pedestrian injured in transport accident	0.716	0.284
F39 Unspecified mood [affective] disorder	0.715	0.285
T33-T35 Frostbite	0.714	0.286
T26-T28 Burns and corrosions confined to eye and internal organs	0.714	0.286
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.714	0.286
C94 Other leukaemias of specified cell type	0.714	0.286
C93 Monocytic leukaemia	0.714	0.286
C86 Other specified types of T/NK-cell lymphoma	0.714	0.286
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.714	0.286
D74 Methaemoglobinaemia	0.714	0.286
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.714	0.286
D71 Functional disorders of polymorphonuclear neutrophils	0.714	0.286
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.713	0.286
E10-E14 Diabetes mellitus	0.713	0.287
T14 Injury of unspecified body region	0.713	0.287
Y59 Other and unspecified vaccines and biological substances	0.713	0.287
Y58 Bacterial vaccines	0.713	0.287
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.713	0.287
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.713	0.287
Y50 Central nervous system stimulants, not elsewhere classified	0.713	0.287
Y48 Anaesthetics and therapeutic gases	0.713	0.287
Y47 Sedatives, hypnotics and antianxiety drugs	0.713	0.287
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.712	0.288
F70-F79 Mental retardation	0.712	0.288
Y60-Y69 Misadventures to patients during surgical and medical care	0.710	0.290
C17 Malignant neoplasm of small intestine	0.708	0.291
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.708	0.292
T94 Sequelae of injuries involving multiple and unspecified body regions	0.707	0.293
B35 Dermatophytosis	0.705	0.295
H54.6 Unqualified visual loss, one eye	0.704	0.296
H54.5 Low vision, one eye	0.704	0.296
H54.3 Unqualified visual loss, both eyes	0.704	0.296
H54.2 Low vision, both eyes	0.704	0.296
H54.1 Blindness, one eye, low vision, other eye	0.704	0.296
M81 Osteoporosis without pathological fracture	0.704	0.296
C18.4 Transverse colon	0.704	0.296
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.704	0.296
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.703	0.297
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.703	0.297
S70-S79 Injuries to the hip and thigh	0.703	0.297
H33.2 Serous retinal detachment	0.703	0.297
W13 Fall from, out of or through building or structure	0.702	0.298
C23 Malignant neoplasm of gallbladder	0.702	0.298
D46.9 Myelodysplastic syndrome, unspecified	0.702	0.298
M54.4 Lumbago with sciatica	0.701	0.299
S68 Traumatic amputation of wrist and hand	0.700	0.300
F48 Other neurotic disorders	0.699	0.301
F44 Dissociative [conversion] disorders	0.699	0.301
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.699	0.301
A50-A64 Infections with a predominantly sexual mode of transmission	0.698	0.302
B15 Acute hepatitis A	0.697	0.303
B85-B89 Pediculosis, acariasis and other infestations	0.697	0.303
B50-B64 Protozoal diseases	0.697	0.303
B20-B24 Human immunodeficiency virus [HIV] disease	0.697	0.303
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.697	0.303
A75-A79 Rickettsioses	0.697	0.303
A70-A74 Other diseases caused by chlamydiae	0.697	0.303
A65-A69 Other spirochaetal diseases	0.697	0.303
A20-A28 Certain zoonotic bacterial diseases	0.697	0.303
A15-A19 Tuberculosis	0.697	0.303
H32 Chorioretinal disorders in diseases classified elsewhere	0.695	0.305
H30 Chorioretinal inflammation	0.695	0.305
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.695	0.305
S64 Injury of nerves at wrist and hand level	0.695	0.305
S56 Injury of muscle and tendon at forearm level	0.695	0.305
M54.8 Other dorsalgia	0.694	0.306
M54.0 Panniculitis affecting regions of neck and back	0.694	0.306
X40-X49 Accidental poisoning by and exposure to noxious substances	0.694	0.306
A41.9 Septicaemia, unspecified	0.694	0.306
H33.0 Retinal detachment with retinal break	0.693	0.307
F80 Specific developmental disorders of speech and language	0.693	0.307
C76.3 Pelvis	0.692	0.308
T79-T79 Certain early complications of trauma	0.691	0.309
M05-M14 Inflammatory polyarthropathies	0.691	0.309
C90.3 Solitary plasmacytoma	0.691	0.309
C90.1 Plasma cell leukaemia	0.691	0.309
Y57.5 X-ray contrast media	0.691	0.309
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.690	0.309
C79.6 Secondary malignant neoplasm of ovary	0.690	0.310
Y57.6 Other diagnostic agents	0.689	0.311
S49 Other and unspecified injuries of shoulder and upper arm	0.689	0.311
M53 Other dorsopathies, not elsewhere classified	0.689	0.311
B17.1 Acute hepatitis C	0.689	0.311
H46-H48 Disorders of optic nerve and visual pathways	0.688	0.312
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.688	0.312
C83.0 Small cell (diffuse)	0.688	0.312
F41.8 Other specified anxiety disorders	0.687	0.312
F41.3 Other mixed anxiety disorders	0.687	0.312
B37.9 Candidiasis, unspecified	0.687	0.313
T91.3 Sequelae of injury of spinal cord	0.687	0.313
D44.3 Pituitary gland	0.686	0.314
S32 Fracture of lumbar spine and pelvis	0.686	0.314
V20-V29 Motorcycle rider injured in transport accident	0.685	0.315
I95-I99 Other and unspecified disorders of the circulatory system	0.685	0.315
F38 Other mood [affective] disorders	0.683	0.317
F34 Persistent mood [affective] disorders	0.683	0.317
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.682	0.318
W17 Other fall from one level to another	0.682	0.318
W16 Diving or jumping into water causing injury other than drowning or submersion	0.682	0.318
W15 Fall from cliff	0.682	0.318
W14 Fall from tree	0.682	0.318
W12 Fall on and from scaffolding	0.682	0.318
W11 Fall on and from ladder	0.682	0.318
W09 Fall involving playground equipment	0.682	0.318
W05 Fall involving wheelchair	0.682	0.318
W04 Fall while being carried or supported by other persons	0.682	0.318
W03 Other fall on same level due to collision with, or pushing by, another person	0.682	0.318
W01 Fall on same level from slipping, tripping and stumbling	0.682	0.318
W00 Fall on same level involving ice and snow	0.682	0.318
G90-G99 Other disorders of the nervous system	0.682	0.318
M00-M03 Infectious arthropathies	0.682	0.318
B37.3 Candidiasis of vulva and vagina	0.681	0.319
H53.9 Visual disturbance, unspecified	0.681	0.319
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.681	0.319
M50.2 Other cervical disk displacement	0.680	0.320
G20 Parkinson's disease	0.680	0.320
M51.3 Other specified intervertebral disk degeneration	0.678	0.322
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.678	0.322
M51.4 Schmorl's nodes	0.678	0.322
Y44.2 Anticoagulants	0.678	0.322
M54.15 Radiculopathy (Thoracolumbar region)	0.677	0.323
M54.14 Radiculopathy (Thoracic region)	0.677	0.323
M54.13 Radiculopathy (Cervicothoracic region)	0.677	0.323
M54.11 Radiculopathy (Occipito-atlanto-axial region)	0.677	0.323
M54.10 Radiculopathy (Multiple sites in spine)	0.677	0.323
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.677	0.323
C43 Malignant melanoma of skin	0.677	0.323
Chapter XV Pregnancy, childbirth and the puerperium	0.676	0.324
H53.6 Night blindness	0.675	0.325
H53.5 Colour vision deficiencies	0.675	0.325
H53.3 Other disorders of binocular vision	0.675	0.325
M50.8 Other cervical disk disorders	0.675	0.325
D80-D89 Certain disorders involving the immune mechanism	0.674	0.325
C18.8 Overlapping lesion of colon	0.674	0.326
W08 Fall involving other furniture	0.673	0.326
T92 Sequelae of injuries of upper limb	0.673	0.327
S50 Superficial injury of forearm	0.673	0.327
C18.1 Appendix	0.672	0.328
I30-I52 Other forms of heart disease	0.672	0.328
B49 Unspecified mycosis	0.672	0.328
X20-X29 Contact with venomous animals and plants	0.672	0.328
X58 Exposure to other specified factors	0.671	0.329
H34.2 Other retinal artery occlusions	0.671	0.329
S62 Fracture at wrist and hand level	0.670	0.330
S81 Open wound of lower leg	0.668	0.332
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.668	0.332
Y43.9 Primarily systemic agent, unspecified	0.667	0.332
Y43.8 Other primarily systemic agents, not elsewhere classified	0.667	0.332
Y43.6 Enzymes, not elsewhere classified	0.667	0.332
Y43.5 Acidifying and alkalising agents	0.667	0.332
Y43.2 Antineoplastic natural products	0.667	0.332
C76.0 Head, face and neck	0.667	0.333
S00-S09 Injuries to the head	0.667	0.333
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.666	0.334
C83.7 Burkitt's tumour	0.666	0.334
C83.6 Undifferentiated (diffuse)	0.666	0.334
C83.5 Lymphoblastic (diffuse)	0.666	0.334
C83.4 Immunoblastic (diffuse)	0.666	0.334
C83.2 Mixed small and large cell (diffuse)	0.666	0.334
H34.8 Other retinal vascular occlusions	0.666	0.334
B44 Aspergillosis	0.666	0.334
F30 Manic episode	0.665	0.334
W18 Other fall on same level	0.665	0.335
B65-B83 Helminthiases	0.664	0.336
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.664	0.336
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.664	0.336
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.664	0.336
H35.9 Retinal disorder, unspecified	0.662	0.338
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.661	0.339
T93.8 Sequelae of other specified injuries of lower limb	0.661	0.339
C77.4 Inguinal and lower limb lymph nodes	0.660	0.340
Y95 Nosocomial condition	0.659	0.341
C21.0 Anus, unspecified	0.658	0.342
S60.8 Other superficial injuries of wrist and hand	0.658	0.342
I20-I25 Ischaemic heart diseases	0.658	0.342
M89 Other disorders of bone	0.657	0.343
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.657	0.343
C81 Hodgkin's disease	0.656	0.343
I42 Cardiomyopathy	0.657	0.343
B48 Other mycoses, not elsewhere classified	0.656	0.344
B47 Mycetoma	0.656	0.344
B46 Zygomycosis	0.656	0.344
B45 Cryptococcosis	0.656	0.344
B43 Chromomycosis and phaeomycotic abscess	0.656	0.344
B42 Sporotrichosis	0.656	0.344
B41 Paracoccidioidomycosis	0.656	0.344
B40 Blastomycosis	0.656	0.344
B39 Histoplasmosis	0.656	0.344
B38 Coccidioidomycosis	0.656	0.344
B36 Other superficial mycoses	0.656	0.344
B18.9 Chronic viral hepatitis, unspecified	0.656	0.344
B18.8 Other chronic viral hepatitis	0.656	0.344
B18.0 Chronic viral hepatitis B with delta-agent	0.656	0.344
V80-V89 Other land transport accidents	0.656	0.344
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.654	0.346
Y57.9 Drug or medicament, unspecified	0.654	0.346
Y41 Other systemic anti-infectives and antiparasitics	0.654	0.346
H35.5 Hereditary retinal dystrophy	0.653	0.346
H35.2 Other proliferative retinopathy	0.653	0.346
H35.1 Retinopathy of prematurity	0.653	0.346
W19.8 Other specified place	0.653	0.347
W19.5 Trade and service area	0.653	0.347
W19.0 Home	0.653	0.347
W19.7 Farm	0.653	0.347
W19.6 Industrial and construction area	0.653	0.347
W19.1 Residential institution	0.653	0.347
S60.9 Superficial injury of wrist and hand, unspecified	0.653	0.347
H33.4 Traction detachment of retina	0.653	0.347
T23 Burn and corrosion of wrist and hand	0.652	0.348
T20 Burn and corrosion of head and neck	0.652	0.348
S90 Superficial injury of ankle and foot	0.652	0.348
M70 Soft tissue disorders related to use, overuse and pressure	0.652	0.348
F33.1 Recurrent depressive disorder, current episode moderate	0.652	0.348
E10 Insulin-dependent diabetes mellitus	0.651	0.349
T98 Sequelae of other and unspecified effects of external causes	0.650	0.350
T95 Sequelae of burns, corrosions and frostbite	0.650	0.350
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.650	0.350
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.650	0.350
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.649	0.351
C85.0 Lymphosarcoma	0.649	0.351
D41.4 Bladder	0.649	0.351
M54.37 Sciatica (Lumbosacral region)	0.649	0.351
F31.0 Bipolar affective disorder, current episode hypomanic	0.648	0.352
H21 Other disorders of iris and ciliary body	0.647	0.353
T31 Burns classified according to extent of body surface involved	0.647	0.353
B18.1 Chronic viral hepatitis B without delta-agent	0.647	0.353
M50.0 Cervical disk disorder with myelopathy	0.647	0.353
C84.4 Peripheral T-cell lymphoma	0.646	0.353
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.646	0.354
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.646	0.354
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.646	0.354
T91.1 Sequelae of fracture of spine	0.646	0.354
M76 Enthesopathies of lower limb, excluding foot	0.645	0.354
I25 Chronic ischaemic heart disease	0.645	0.355
C77.5 Intrapelvic lymph nodes	0.645	0.355
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.644	0.356
X60-X84 Intentional self-harm	0.643	0.357
A80-A89 Viral infections of the central nervous system	0.643	0.357
Y53.1 Other antacids and anti-gastric-secretion drugs	0.642	0.358
S51 Open wound of forearm	0.641	0.359
M54.9 Dorsalgia, unspecified	0.641	0.359
C24.1 Ampulla of Vater	0.641	0.359
M92 Other juvenile osteochondrosis	0.640	0.360
M79 Other soft tissue disorders, not elsewhere classified	0.640	0.360
H33.3 Retinal breaks without detachment	0.639	0.361
I95 Hypotension	0.638	0.362
S12 Fracture of neck	0.638	0.362
B90-B94 Sequelae of infectious and parasitic diseases	0.638	0.362
T21.2 Burn of second degree of trunk	0.638	0.362
S91 Open wound of ankle and foot	0.636	0.364
F99-F99 Unspecified mental disorder	0.635	0.364
S86 Injury of muscle and tendon at lower leg level	0.634	0.365
S89 Other and unspecified injuries of lower leg	0.634	0.366
H18.9 Disorder of cornea, unspecified	0.634	0.366
M94 Other disorders of cartilage	0.634	0.366
X51 Travel and motion	0.633	0.367
C95.9 Leukaemia, unspecified	0.633	0.367
H18.4 Corneal degeneration	0.633	0.367
S82 Fracture of lower leg, including ankle	0.633	0.367
M90.7 Fracture of bone in neoplastic disease	0.633	0.367
F32.3 Severe depressive episode with psychotic symptoms	0.633	0.367
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.632	0.367
F60-F69 Disorders of adult personality and behaviour	0.632	0.368
Y46.4 Iminostilbenes	0.632	0.368
C32 Malignant neoplasm of larynx	0.631	0.369
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.630	0.370
M91 Juvenile osteochondrosis of hip and pelvis	0.629	0.371
S80 Superficial injury of lower leg	0.629	0.371
O60-O75 Complications of labour and delivery	0.629	0.371
E14 Unspecified diabetes mellitus	0.629	0.371
M54.5 Low back pain	0.629	0.371
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.628	0.372
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.628	0.372
H17 Corneal scars and opacities	0.628	0.372
H15 Disorders of sclera	0.628	0.372
T14.0 Superficial injury of unspecified body region	0.628	0.372
A40 Streptococcal septicaemia	0.627	0.373
Y85 Sequelae of transport accidents	0.627	0.373
D40.1 Testis	0.627	0.373
H43-H45 Disorders of vitreous body and globe	0.627	0.373
I95.1 Orthostatic hypotension	0.627	0.373
Y54.4 Loop [high-ceiling] diuretics	0.627	0.373
S31 Open wound of abdomen, lower back and pelvis	0.626	0.374
E10.9 Without complications	0.626	0.374
T78 Adverse effects, not elsewhere classified	0.626	0.374
W10 Fall on and from stairs and steps	0.625	0.375
C43.7 Malignant melanoma of lower limb, including hip	0.625	0.375
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.625	0.375

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations