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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1333005
log Bayes Factor = 17.474
Chromosome 9   position 130,042,369  (GRCh37) Explore rs1333005 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.998 0.002 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.998 0.002 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.997 0.003 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.997 0.003 0.000
Chapter XI Diseases of the digestive system
0.997 0.003 0.000
Chapter I Certain infectious and parasitic diseases
0.996 0.004 0.000
Chapter VI Diseases of the nervous system
0.995 0.005 0.000
K80 Cholelithiasis
0.994 0.006 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.990 0.010 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.989 0.011 0.000
Chapter XX External causes of morbidity and mortality
0.988 0.012 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.987 0.013 0.000
Z80 Family history of malignant neoplasm
0.983 0.017 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.979 0.021 0.000
Chapter II Neoplasms
0.978 0.022 0.000
Chapter XIV Diseases of the genitourinary system
0.974 0.026 0.000
Z03.8 Observation for other suspected diseases and conditions
0.972 0.028 0.000
E70-E90 Metabolic disorders
0.970 0.030 0.000
G90-G99 Other disorders of the nervous system
0.970 0.030 0.000
N30-N39 Other diseases of urinary system
0.967 0.033 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.961 0.039 0.000
Chapter V Mental and behavioural disorders
0.961 0.039 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.951 0.049 0.000
N39 Other disorders of urinary system
0.950 0.050 0.000
N39.3 Stress incontinence
0.948 0.052 0.000
K86 Other diseases of pancreas
0.947 0.053 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.946 0.054 0.000
Chapter X Diseases of the respiratory system
0.946 0.054 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.939 0.061 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.938 0.062 0.000
G93 Other disorders of brain
0.938 0.062 0.000
Z12 Special screening examination for neoplasms
0.931 0.069 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.931 0.069 0.000
B95-B98 Bacterial, viral and other infectious agents
0.927 0.073 0.000
Z93 Artificial opening status
0.925 0.075 0.000
K70-K77 Diseases of liver
0.924 0.076 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.922 0.078 0.000
N17-N19 Renal failure
0.922 0.078 0.000
Z80.0 Family history of malignant neoplasm of digestive organs
0.917 0.083 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.916 0.084 0.000
E83 Disorders of mineral metabolism
0.912 0.088 0.000
K83 Other diseases of biliary tract
0.910 0.090 0.000
Chapter XXII Codes for special purposes
0.909 0.091 0.000
E65-E68 Obesity and other hyperalimentation
0.906 0.094 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.905 0.095 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.904 0.096 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.904 0.096 0.000
K90-K93 Other diseases of the digestive system
0.902 0.098 0.000
Y43 Primarily systemic agents
0.898 0.102 0.000
M70-M79 Other soft tissue disorders
0.895 0.105 0.000
J40-J47 Chronic lower respiratory diseases
0.895 0.105 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.894 0.106 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.893 0.107 0.000
M20-M25 Other joint disorders
0.890 0.110 0.000
Z96 Presence of other functional implants
0.889 0.111 0.000
Z13 Special screening examination for other diseases and disorders
0.889 0.111 0.000
E50-E64 Other nutritional deficiencies
0.889 0.111 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.889 0.111 0.000
E10-E14 Diabetes mellitus
0.887 0.113 0.000
J44 Other chronic obstructive pulmonary disease
0.886 0.114 0.000
Chapter IX Diseases of the circulatory system
0.886 0.114 0.000
N17 Acute renal failure
0.883 0.117 0.000
G93.3 Postviral fatigue syndrome
0.880 0.120 0.000
Z03.4 Observation for suspected myocardial infarction
0.879 0.121 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.879 0.121 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.878 0.122 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.874 0.126 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.874 0.126 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.874 0.126 0.000
E83.5 Disorders of calcium metabolism
0.872 0.128 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.872 0.128 0.000
M20 Acquired deformities of fingers and toes
0.872 0.128 0.000
S60-S69 Injuries to the wrist and hand
0.869 0.131 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.869 0.131 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.860 0.140 0.000
Z80.3 Family history of malignant neoplasm of breast
0.858 0.142 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.858 0.142 0.000
A00-A09 Intestinal infectious diseases
0.857 0.143 0.000
C83.3 Large cell (diffuse)
0.856 0.144 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.856 0.144 0.000
N17.9 Acute renal failure, unspecified
0.855 0.145 0.000
Z03.9 Observation for suspected disease or condition, unspecified
0.855 0.145 0.000
B35-B49 Mycoses
0.855 0.145 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.850 0.150 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.847 0.153 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.847 0.153 0.000
Z81 Family history of mental and behavioural disorders
0.847 0.153 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.846 0.154 0.000
K86.2 Cyst of pancreas
0.845 0.155 0.000
Y43.3 Other antineoplastic drugs
0.845 0.155 0.000
E11 Non-insulin-dependent diabetes mellitus
0.842 0.158 0.000
Z96.8 Presence of other specified functional implants
0.842 0.158 0.000
M20.4 Other hammer toe(s) (acquired)
0.841 0.159 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.841 0.159 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.840 0.160 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.839 0.161 0.000
I77 Other disorders of arteries and arterioles
0.839 0.161 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.839 0.161 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.838 0.162 0.000
N35 Urethral stricture
0.837 0.163 0.000
G40-G47 Episodic and paroxysmal disorders
0.835 0.165 0.000
J09-J18 Influenza and pneumonia
0.835 0.165 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.834 0.166 0.000
K86.1 Other chronic pancreatitis
0.831 0.169 0.000
D10-D36 Benign neoplasms
0.830 0.170 0.000
Z80.4 Family history of malignant neoplasm of genital organs
0.830 0.170 0.000
E53 Deficiency of other B group vitamins
0.829 0.171 0.000
L20-L30 Dermatitis and eczema
0.828 0.172 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.828 0.172 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.828 0.172 0.000
Z12.1 Special screening examination for neoplasm of intestinal tract
0.825 0.175 0.000
Q60-Q64 Congenital malformations of the urinary system
0.824 0.176 0.000
M79.6 Pain in limb
0.819 0.181 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.815 0.185 0.000
K82 Other diseases of gallbladder
0.814 0.186 0.000
S20-S29 Injuries to the thorax
0.814 0.186 0.000
I77.1 Stricture of artery
0.814 0.186 0.000
N40-N51 Diseases of male genital organs
0.814 0.186 0.000
K85 Acute pancreatitis
0.812 0.188 0.000
A30-A49 Other bacterial diseases
0.811 0.189 0.000
W20-W49 Exposure to inanimate mechanical forces
0.810 0.190 0.000
E66 Obesity
0.810 0.190 0.000
K83.1 Obstruction of bile duct
0.808 0.192 0.000
V10-V19 Pedal cyclist injured in transport accident
0.808 0.192 0.000
J95-J99 Other diseases of the respiratory system
0.806 0.194 0.000
G93.4 Encephalopathy, unspecified
0.806 0.194 0.000
K70 Alcoholic liver disease
0.806 0.194 0.000
Z98 Other postsurgical states
0.806 0.194 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.805 0.195 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.803 0.197 0.000
E78.0 Pure hypercholesterolaemia
0.800 0.200 0.000
Y86 Sequelae of other accidents
0.799 0.201 0.000
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs
0.796 0.204 0.000
Z11.0 Special screening examination for intestinal infectious diseases
0.794 0.206 0.000
Z92 Personal history of medical treatment
0.794 0.206 0.000
K83.0 Cholangitis
0.793 0.207 0.000
K92 Other diseases of digestive system
0.791 0.209 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.790 0.210 0.000
Z93.2 Ileostomy status
0.790 0.210 0.000
N41 Inflammatory diseases of prostate
0.789 0.211 0.000
C85.1 B-cell lymphoma, unspecified
0.788 0.212 0.000
Z12.8 Special screening examination for neoplasm of other sites
0.788 0.212 0.000
B15-B19 Viral hepatitis
0.788 0.212 0.000
I77.6 Arteritis, unspecified
0.787 0.213 0.000
E11.4 With neurological complications
0.787 0.213 0.000
B99-B99 Other infectious diseases
0.786 0.214 0.000
E53.8 Deficiency of other specified B group vitamins
0.785 0.215 0.000
Z00.0 General medical examination
0.785 0.215 0.000
G30-G32 Other degenerative diseases of the nervous system
0.784 0.216 0.000
Z13.9 Special screening examination, unspecified
0.783 0.217 0.000
Y40 Systemic antibiotics
0.783 0.217 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.782 0.218 0.000
F99-F99 Unspecified mental disorder
0.782 0.218 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.782 0.218 0.000
L30 Other dermatitis
0.781 0.219 0.000
Z93.6 Other artificial openings of urinary tract status
0.779 0.221 0.000
Z96.0 Presence of urogenital implants
0.779 0.221 0.000
Z93.3 Colostomy status
0.778 0.222 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.777 0.223 0.000
G91 Hydrocephalus
0.777 0.223 0.000
T91 Sequelae of injuries of neck and trunk
0.775 0.225 0.000
E78.4 Other hyperlipidaemia
0.773 0.227 0.000
K76 Other diseases of liver
0.772 0.228 0.000
D25 Leiomyoma of uterus
0.772 0.228 0.000
I60-I69 Cerebrovascular diseases
0.772 0.228 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.771 0.229 0.000
N39.8 Other specified disorders of urinary system
0.771 0.229 0.000
E40-E46 Malnutrition
0.771 0.229 0.000
N34 Urethritis and urethral syndrome
0.769 0.231 0.000
M86-M90 Other osteopathies
0.768 0.232 0.000
I27 Other pulmonary heart diseases
0.765 0.235 0.000
Z13.1 Special screening examination for diabetes mellitus
0.765 0.235 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.765 0.235 0.000
F03 Unspecified dementia
0.765 0.235 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.764 0.236 0.000
Z13.5 Special screening examination for eye and ear disorders
0.762 0.238 0.000
D17 Benign lipomatous neoplasm
0.762 0.238 0.000
F60-F69 Disorders of adult personality and behaviour
0.761 0.239 0.000
R05 Cough
0.761 0.239 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.760 0.240 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.759 0.241 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.759 0.241 0.000
K74 Fibrosis and cirrhosis of liver
0.757 0.243 0.000
N36 Other disorders of urethra
0.756 0.244 0.000
F41 Other anxiety disorders
0.755 0.245 0.000
M79.8 Other specified soft tissue disorders
0.755 0.245 0.000
Z89 Acquired absence of limb
0.755 0.245 0.000
S90-S99 Injuries to the ankle and foot
0.753 0.246 0.000
Z94 Transplanted organ and tissue status
0.753 0.247 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.751 0.249 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.751 0.249 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.751 0.249 0.000
Y95 Nosocomial condition
0.751 0.249 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.751 0.249 0.000
D25.9 Leiomyoma of uterus, unspecified
0.751 0.249 0.000
Z88.5 Personal history of allergy to narcotic agent
0.750 0.250 0.000
E11.3 With ophthalmic complications
0.750 0.250 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.749 0.251 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.749 0.251 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.748 0.252 0.000
V20-V29 Motorcycle rider injured in transport accident
0.747 0.253 0.000
Q61 Cystic kidney disease
0.747 0.253 0.000
L30.9 Dermatitis, unspecified
0.747 0.253 0.000
Chapter VII Diseases of the eye and adnexa
0.747 0.253 0.000
G40 Epilepsy
0.746 0.254 0.000
Z73 Problems related to life-management difficulty
0.746 0.254 0.000
Z74 Problems related to care-provider dependency
0.745 0.255 0.000
S80-S89 Injuries to the knee and lower leg
0.745 0.255 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.744 0.256 0.000
N35.9 Urethral stricture, unspecified
0.744 0.256 0.000
K65-K67 Diseases of peritoneum
0.743 0.257 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.742 0.258 0.000
B07 Viral warts
0.742 0.258 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.742 0.258 0.000
F30-F39 Mood [affective] disorders
0.741 0.259 0.000
Z81.8 Family history of other mental and behavioural disorders
0.739 0.261 0.000
N32 Other disorders of bladder
0.736 0.264 0.000
G96 Other disorders of central nervous system
0.736 0.264 0.000
T92 Sequelae of injuries of upper limb
0.735 0.265 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.735 0.265 0.000
Z91.8 Personal history of other specified risk-factors, not elsewhere classified
0.735 0.265 0.000
I26 Pulmonary embolism
0.734 0.266 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.734 0.266 0.000
B25-B34 Other viral diseases
0.734 0.266 0.000
Y52 Agents primarily affecting the cardiovascular system
0.733 0.267 0.000
E65 Localised adiposity
0.733 0.267 0.000
E87.5 Hyperkalaemia
0.733 0.267 0.000
M72 Fibroblastic disorders
0.733 0.267 0.000
Z96.7 Presence of other bone and tendon implants
0.733 0.267 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.732 0.268 0.000
S70-S79 Injuries to the hip and thigh
0.731 0.269 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.730 0.270 0.000
Q80-Q89 Other congenital malformations
0.728 0.271 0.000
K35-K38 Diseases of appendix
0.728 0.272 0.000
U80 Agent resistant to penicillin and related antibiotics
0.728 0.272 0.000
G82 Paraplegia and tetraplegia
0.727 0.273 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.727 0.273 0.000
S62 Fracture at wrist and hand level
0.727 0.273 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.726 0.274 0.000
B37 Candidiasis
0.725 0.275 0.000
Z76 Persons encountering health services in other circumstances
0.725 0.275 0.000
Z80.8 Family history of malignant neoplasm of other organs or systems
0.725 0.275 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.724 0.275 0.000
S10-S19 Injuries to the neck
0.724 0.276 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.724 0.276 0.000
K86.0 Alcohol-induced chronic pancreatitis
0.724 0.276 0.000
D00-D09 In situ neoplasms
0.723 0.277 0.000
R07 Pain in throat and chest
0.723 0.277 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.722 0.278 0.000
Z03.1 Observation for suspected malignant neoplasm
0.722 0.278 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.722 0.278 0.000
M31 Other necrotising vasculopathies
0.721 0.278 0.000
I10-I15 Hypertensive diseases
0.721 0.279 0.000
X60-X84 Intentional self-harm
0.721 0.279 0.000
G93.8 Other specified disorders of brain
0.721 0.279 0.000
E78.8 Other disorders of lipoprotein metabolism
0.720 0.279 0.000
Y43.4 Immunosuppressive agents
0.720 0.280 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.720 0.280 0.000
N41.9 Inflammatory disease of prostate, unspecified
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
J18 Pneumonia, organism unspecified
0.716 0.284 0.000
Y44 Agents primarily affecting blood constituents
0.716 0.284 0.000
Z10 Routine general health check-up of defined subpopulation
0.716 0.284 0.000
Z57 Occupational exposure to risk-factors
0.715 0.284 0.000
M79.60 Pain in limb (Multiple sites)
0.715 0.285 0.000
Z84 Family history of other conditions
0.715 0.285 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.715 0.285 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.714 0.286 0.000
B65-B83 Helminthiases
0.714 0.286 0.000
B50-B64 Protozoal diseases
0.714 0.286 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.714 0.286 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.714 0.286 0.000
A80-A89 Viral infections of the central nervous system
0.714 0.286 0.000
A75-A79 Rickettsioses
0.714 0.286 0.000
A70-A74 Other diseases caused by chlamydiae
0.714 0.286 0.000
A65-A69 Other spirochaetal diseases
0.714 0.286 0.000
A20-A28 Certain zoonotic bacterial diseases
0.714 0.286 0.000
A15-A19 Tuberculosis
0.714 0.286 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.713 0.287 0.000
K80.3 Calculus of bile duct with cholangitis
0.712 0.287 0.000
K80.8 Other cholelithiasis
0.712 0.287 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.712 0.287 0.000
Z12.0 Special screening examination for neoplasm of stomach
0.712 0.288 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.711 0.289 0.000
K86.8 Other specified diseases of pancreas
0.711 0.289 0.000
G70-G73 Diseases of myoneural junction and muscle
0.711 0.289 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.711 0.289 0.000
Z03.6 Observation for suspected toxic effect from ingested substance
0.710 0.290 0.000
Z03.2 Observation for suspected mental and behavioural disorders
0.710 0.290 0.000
Z03.0 Observation for suspected tuberculosis
0.710 0.290 0.000
I61 Intracerebral haemorrhage
0.710 0.290 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.710 0.290 0.000
N41.1 Chronic prostatitis
0.709 0.291 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.708 0.292 0.000
Y35-Y36 Legal intervention and operations of war
0.708 0.292 0.000
Y10-Y34 Event of undetermined intent
0.708 0.292 0.000
Y00-Y09 Assault
0.708 0.292 0.000
X85-X99 Assault
0.708 0.292 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.708 0.292 0.000
X50-X57 Overexertion, travel and privation
0.708 0.292 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.708 0.292 0.000
X30-X39 Exposure to forces of nature
0.708 0.292 0.000
X20-X29 Contact with venomous animals and plants
0.708 0.292 0.000
X10-X19 Contact with heat and hot substances
0.708 0.292 0.000
X00-X09 Exposure to smoke, fire and flames
0.708 0.292 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.708 0.292 0.000
W75-W84 Other accidental threats to breathing
0.708 0.292 0.000
W65-W74 Accidental drowning and submersion
0.708 0.292 0.000
W50-W64 Exposure to animate mechanical forces
0.708 0.292 0.000
V98-V99 Other and unspecified transport accidents
0.708 0.292 0.000
V95-V97 Air and space transport accidents
0.708 0.292 0.000
V90-V94 Water transport accidents
0.708 0.292 0.000
V80-V89 Other land transport accidents
0.708 0.292 0.000
V70-V79 Bus occupant injured in transport accident
0.708 0.292 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.708 0.292 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.708 0.292 0.000
V40-V49 Car occupant injured in transport accident
0.708 0.292 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.708 0.292 0.000
V01-V09 Pedestrian injured in transport accident
0.708 0.292 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.708 0.292 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.708 0.292 0.000
F01 Vascular dementia
0.708 0.292 0.000
M21 Other acquired deformities of limbs
0.707 0.292 0.000
N72 Inflammatory disease of cervix uteri
0.706 0.294 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.705 0.294 0.000
E66.9 Obesity, unspecified
0.705 0.295 0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues
0.705 0.295 0.000
Z80.6 Family history of leukaemia
0.705 0.295 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.704 0.296 0.000
K80.1 Calculus of gallbladder with other cholecystitis
0.704 0.296 0.000
M79.69 Pain in limb (Site unspecified)
0.704 0.296 0.000
J47 Bronchiectasis
0.704 0.296 0.000
Z63 Other problems related to primary support group, including family circumstances
0.703 0.297 0.000
G81 Hemiplegia
0.702 0.298 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.702 0.298 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.701 0.298 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.701 0.298 0.000
K82.8 Other specified diseases of gallbladder
0.701 0.299 0.000
E83.4 Disorders of magnesium metabolism
0.700 0.300 0.000
D60-D64 Aplastic and other anaemias
0.700 0.300 0.000
N19 Unspecified renal failure
0.699 0.301 0.000
S60 Superficial injury of wrist and hand
0.698 0.302 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.698 0.302 0.000
K86.9 Disease of pancreas, unspecified
0.698 0.302 0.000
D36 Benign neoplasm of other and unspecified sites
0.698 0.302 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.697 0.303 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.697 0.303 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.697 0.303 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.696 0.303 0.000
S61 Open wound of wrist and hand
0.696 0.304 0.000
S40-S49 Injuries to the shoulder and upper arm
0.696 0.304 0.000
E85 Amyloidosis
0.695 0.305 0.000
E84 Cystic fibrosis
0.695 0.305 0.000
E79 Disorders of purine and pyrimidine metabolism
0.695 0.305 0.000
E77 Disorders of glycoprotein metabolism
0.695 0.305 0.000
E76 Disorders of glycosaminoglycan metabolism
0.695 0.305 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.695 0.305 0.000
E74 Other disorders of carbohydrate metabolism
0.695 0.305 0.000
E73 Lactose intolerance
0.695 0.305 0.000
E72 Other disorders of amino-acid metabolism
0.695 0.305 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.695 0.305 0.000
E70 Disorders of aromatic amino-acid metabolism
0.695 0.305 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.695 0.305 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.695 0.305 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.695 0.305 0.000
G90 Disorders of autonomic nervous system
0.695 0.305 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.695 0.305 0.000
G92 Toxic encephalopathy
0.695 0.305 0.000
M00-M03 Infectious arthropathies
0.695 0.305 0.000
E11.6 With other specified complications
0.695 0.305 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.695 0.305 0.000
N37 Urethral disorders in diseases classified elsewhere
0.693 0.306 0.000
N33 Bladder disorders in diseases classified elsewhere
0.693 0.306 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.693 0.307 0.000
Z97 Presence of other devices
0.693 0.307 0.000
Z29 Need for other prophylactic measures
0.693 0.307 0.000
R41.0 Disorientation, unspecified
0.693 0.307 0.000
Z72 Problems related to lifestyle
0.692 0.308 0.000
E88 Other metabolic disorders
0.691 0.308 0.000
F80-F89 Disorders of psychological development
0.691 0.309 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.690 0.310 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.689 0.311 0.000
C95 Leukaemia of unspecified cell type
0.689 0.311 0.000
C94 Other leukaemias of specified cell type
0.689 0.311 0.000
C93 Monocytic leukaemia
0.689 0.311 0.000
C88 Malignant immunoproliferative diseases
0.689 0.311 0.000
C86 Other specified types of T/NK-cell lymphoma
0.689 0.311 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.689 0.311 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.689 0.311 0.000
F70-F79 Mental retardation
0.689 0.311 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.689 0.311 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.688 0.312 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.688 0.312 0.000
A04 Other bacterial intestinal infections
0.688 0.312 0.000
N76 Other inflammation of vagina and vulva
0.687 0.313 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.687 0.313 0.000
S68 Traumatic amputation of wrist and hand
0.686 0.314 0.000
I12 Hypertensive renal disease
0.686 0.314 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.685 0.314 0.000
Q00-Q07 Congenital malformations of the nervous system
0.685 0.315 0.000
J60-J70 Lung diseases due to external agents
0.685 0.315 0.000
Z01.6 Radiological examination, not elsewhere classified
0.684 0.316 0.000
N70 Salpingitis and oophoritis
0.684 0.316 0.000
N71 Inflammatory disease of uterus, except cervix
0.683 0.317 0.000
Y59 Other and unspecified vaccines and biological substances
0.681 0.318 0.000
Y58 Bacterial vaccines
0.681 0.318 0.000
Y57 Other and unspecified drugs and medicaments
0.681 0.318 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.681 0.318 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.681 0.318 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.681 0.318 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.681 0.318 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.681 0.318 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.681 0.318 0.000
Y48 Anaesthetics and therapeutic gases
0.681 0.318 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.681 0.318 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.681 0.318 0.000
N39.2 Orthostatic proteinuria, unspecified
0.681 0.319 0.000
N39.1 Persistent proteinuria, unspecified
0.681 0.319 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.681 0.319 0.000
E78.5 Hyperlipidaemia, unspecified
0.681 0.319 0.000
Z11.2 Special screening examination for other bacterial diseases
0.681 0.319 0.000
T90 Sequelae of injuries of head
0.681 0.319 0.000
M50-M54 Other dorsopathies
0.680 0.320 0.000
D17.9 Benign lipomatous neoplasm, unspecified
0.680 0.320 0.000
D46 Myelodysplastic syndromes
0.680 0.320 0.000
K80.4 Calculus of bile duct with cholecystitis
0.680 0.320 0.000
Y85 Sequelae of transport accidents
0.680 0.320 0.000
Q61.3 Polycystic kidney, unspecified
0.680 0.320 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.679 0.321 0.000
J18.9 Pneumonia, unspecified
0.679 0.321 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.679 0.321 0.000
T33-T35 Frostbite
0.678 0.322 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.678 0.322 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.678 0.322 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.678 0.322 0.000
T00-T07 Injuries involving multiple body regions
0.678 0.322 0.000
G93.0 Cerebral cysts
0.678 0.322 0.000
E78.2 Mixed hyperlipidaemia
0.678 0.322 0.000
G44 Other headache syndromes
0.677 0.323 0.000
Chapter VIII Diseases of the ear and mastoid process
0.676 0.324 0.000
M80-M85 Disorders of bone density and structure
0.676 0.324 0.000
C81 Hodgkin's disease
0.676 0.324 0.000
E20-E35 Disorders of other endocrine glands
0.675 0.324 0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.675 0.325 0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.675 0.325 0.000
Y88 Sequelae of surgical and medical care as external cause
0.675 0.325 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.674 0.325 0.000
M79.5 Residual foreign body in soft tissue
0.674 0.326 0.000
M24 Other specific joint derangements
0.674 0.326 0.000
F40 Phobic anxiety disorders
0.674 0.326 0.000
M91-M94 Chondropathies
0.674 0.326 0.000
M60-M63 Disorders of muscles
0.674 0.326 0.000
J46 Status asthmaticus
0.673 0.327 0.000
G62 Other polyneuropathies
0.673 0.327 0.000
G93.6 Cerebral oedema
0.673 0.327 0.000
R04 Haemorrhage from respiratory passages
0.673 0.327 0.000
M05-M14 Inflammatory polyarthropathies
0.673 0.327 0.000
G93.9 Disorder of brain, unspecified
0.672 0.327 0.000
G93.7 Reye's syndrome
0.672 0.327 0.000
G93.5 Compression of brain
0.672 0.327 0.000
G93.2 Benign intracranial hypertension
0.672 0.327 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.672 0.327 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.672 0.328 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.672 0.328 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.672 0.328 0.000
D50-D53 Nutritional anaemias
0.671 0.329 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.671 0.329 0.000
G57 Mononeuropathies of lower limb
0.670 0.330 0.000
M79.7 Fibromyalgia
0.669 0.331 0.000
K85.9 Acute pancreatitis, unspecified
0.668 0.332 0.000
Z12.9 Special screening examination for neoplasm, unspecified
0.668 0.332 0.000
Z12.6 Special screening examination for neoplasm of bladder
0.668 0.332 0.000
Z12.5 Special screening examination for neoplasm of prostate
0.668 0.332 0.000
Z12.4 Special screening examination for neoplasm of cervix
0.668 0.332 0.000
Z12.3 Special screening examination for neoplasm of breast
0.668 0.332 0.000
Z12.2 Special screening examination for neoplasm of respiratory organs
0.668 0.332 0.000
H30-H36 Disorders of choroid and retina
0.668 0.332 0.000
G20-G26 Extrapyramidal and movement disorders
0.667 0.333 0.000
B35 Dermatophytosis
0.667 0.333 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.667 0.333 0.000
M79.67 Pain in limb (Ankle and foot)
0.667 0.333 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.667 0.333 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.666 0.334 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.666 0.334 0.000
I27.2 Other secondary pulmonary hypertension
0.666 0.334 0.000
K70.0 Alcoholic fatty liver
0.665 0.335 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.665 0.335 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.664 0.336 0.000
S00-S09 Injuries to the head
0.663 0.337 0.000
Z93.9 Artificial opening status, unspecified
0.663 0.337 0.000
Z93.8 Other artificial opening status
0.663 0.337 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.663 0.337 0.000
Z93.0 Tracheostomy status
0.663 0.337 0.000
K77 Liver disorders in diseases classified elsewhere
0.662 0.337 0.000
K73 Chronic hepatitis, not elsewhere classified
0.662 0.337 0.000
K71 Toxic liver disease
0.662 0.337 0.000
K72 Hepatic failure, not elsewhere classified
0.662 0.338 0.000
E78.6 Lipoprotein deficiency
0.661 0.339 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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