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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs13343954
log Bayes Factor = 1.72027
Chromosome 19   position 33,527,888  (GRCh37) Explore rs13343954 on Ensembl!
Variant rs13343954 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10 Insulin-dependent diabetes mellitus
0.936 0.064 0.000
E10.9 Without complications
0.934 0.066 0.000
E10.3 With ophthalmic complications
0.906 0.094 0.000
E10.1 With ketoacidosis
0.843 0.157 0.000
E10-E14 Diabetes mellitus
0.829 0.171 0.000
E11 Non-insulin-dependent diabetes mellitus
0.798 0.202 0.000
E11.3 With ophthalmic complications
0.795 0.205 0.000
E10.5 With peripheral circulatory complications
0.793 0.207 0.000
E10.4 With neurological complications
0.785 0.215 0.000
E10.2 With renal complications
0.760 0.240 0.000
E10.0 With coma
0.724 0.276 0.000
E11.4 With neurological complications
0.706 0.294 0.000
E10.7 With multiple complications
0.671 0.329 0.000
E10.6 With other specified complications
0.667 0.333 0.000
E11.8 With unspecified complications
0.636 0.364 0.000
E11.2 With renal complications
0.635 0.365 0.000
E14 Unspecified diabetes mellitus
0.602 0.398 0.000
E10.8 With unspecified complications
0.596 0.403 0.000
E12 Malnutrition-related diabetes mellitus
0.595 0.405 0.000
K92.0 Haematemesis
0.594 0.406 0.000
E11.7 With multiple complications
0.572 0.428 0.000
E13 Other specified diabetes mellitus
0.559 0.441 0.000
K92 Other diseases of digestive system
0.558 0.442 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.537 0.463 0.000
K92.1 Melaena
0.516 0.484 0.000
E14.3 With ophthalmic complications
0.497 0.503 0.000
H36.0 Diabetic retinopathy
0.488 0.512 0.000
E11.5 With peripheral circulatory complications
0.481 0.519 0.000
E14.1 With ketoacidosis
0.439 0.561 0.000
E11.1 With ketoacidosis
0.436 0.564 0.000
E14.8 With unspecified complications
0.432 0.568 0.000
E14.7 With multiple complications
0.432 0.568 0.000
E14.6 With other specified complications
0.432 0.568 0.000
E14.5 With peripheral circulatory complications
0.432 0.568 0.000
E14.4 With neurological complications
0.432 0.568 0.000
E14.2 Withrenal complications
0.432 0.568 0.000
E14.0 With coma
0.432 0.568 0.000
E11.0 With coma
0.429 0.570 0.000
E12.9 Without complications
0.426 0.573 0.000
E12.8 With unspecified complications
0.426 0.573 0.000
E12.7 With multiple complications
0.426 0.573 0.000
E12.6 With other specified complications
0.426 0.573 0.000
E12.5 With peripheral circulatory complications
0.426 0.573 0.000
E12.4 With neurological complications
0.426 0.573 0.000
E12.3 With ophthalmic complications
0.426 0.573 0.000
E12.2 With renal complications
0.426 0.573 0.000
E12.1 With ketoacidosis
0.426 0.573 0.000
E12.0 With coma
0.426 0.573 0.000
E11.6 With other specified complications
0.411 0.588 0.000
E13.8 With unspecified complications
0.401 0.599 0.000
E13.7 With multiple complications
0.401 0.599 0.000
E13.6 With other specified complications
0.401 0.599 0.000
E13.5 With peripheral circulatory complications
0.401 0.599 0.000
E13.4 With neurological complications
0.401 0.599 0.000
E13.3 With ophthalmic complications
0.401 0.599 0.000
E13.2 With renal complications
0.401 0.599 0.000
E13.1 With ketoacidosis
0.401 0.599 0.000
E13.0 With coma
0.401 0.599 0.000
H36 Retinal disorders in diseases classified elsewhere
0.390 0.610 0.000
E13.9 Without complications
0.365 0.635 0.000
K92.8 Other specified diseases of digestive system
0.365 0.635 0.000
H53 Visual disturbances
0.355 0.645 0.000
H53.8 Other visual disturbances
0.353 0.647 0.000
K92.9 Disease of digestive system, unspecified
0.341 0.659 0.000
H53.4 Visual field defects
0.339 0.661 0.000
H53-H54 Visual disturbances and blindness
0.330 0.670 0.000
E14.9 Without complications
0.326 0.674 0.000
H53.1 Subjective visual disturbances
0.324 0.676 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.321 0.679 0.000
Chapter V Mental and behavioural disorders
0.320 0.680 0.000
H30-H36 Disorders of choroid and retina
0.320 0.680 0.000
Chapter VII Diseases of the eye and adnexa
0.318 0.682 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.315 0.685 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.314 0.686 0.000
F60-F69 Disorders of adult personality and behaviour
0.311 0.689 0.000
F17.1 Harmful use
0.309 0.691 0.000
# Top node
0.303 0.697 0.000
F60 Specific personality disorders
0.303 0.697 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.300 0.700 0.000
Chapter VI Diseases of the nervous system
0.299 0.701 0.000
H53.2 Diplopia
0.299 0.701 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.298 0.702 0.000
G30-G32 Other degenerative diseases of the nervous system
0.298 0.702 0.000
H40-H42 Glaucoma
0.294 0.706 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.289 0.711 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.289 0.711 0.000
F60.3 Emotionally unstable personality disorder
0.282 0.718 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.280 0.720 0.000
H91.9 Hearing loss, unspecified
0.279 0.721 0.000
G40 Epilepsy
0.278 0.722 0.000
H40 Glaucoma
0.277 0.723 0.000
G31.2 Degeneration of nervous system due to alcohol
0.276 0.724 0.000
G90-G99 Other disorders of the nervous system
0.275 0.725 0.000
F30-F39 Mood [affective] disorders
0.274 0.726 0.000
G40-G47 Episodic and paroxysmal disorders
0.274 0.726 0.000
F17.2 Dependence syndrome
0.271 0.729 0.000
F99-F99 Unspecified mental disorder
0.271 0.729 0.000
H40.9 Glaucoma, unspecified
0.271 0.729 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.269 0.731 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.268 0.732 0.000
G40.9 Epilepsy, unspecified
0.268 0.732 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.267 0.733 0.000
H91 Other hearing loss
0.266 0.734 0.000
I72 Other aneurysm
0.266 0.734 0.000
I72.4 Aneurysm of artery of lower extremity
0.265 0.735 0.000
F11 Mental and behavioural disorders due to use of opioids
0.263 0.737 0.000
Chapter IX Diseases of the circulatory system
0.258 0.742 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.257 0.743 0.000
Chapter VIII Diseases of the ear and mastoid process
0.256 0.744 0.000
F20 Schizophrenia
0.256 0.744 0.000
I74 Arterial embolism and thrombosis
0.256 0.744 0.000
H53.6 Night blindness
0.255 0.745 0.000
H53.5 Colour vision deficiencies
0.255 0.745 0.000
H53.3 Other disorders of binocular vision
0.255 0.745 0.000
H90-H95 Other disorders of ear
0.254 0.746 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.254 0.746 0.000
G93 Other disorders of brain
0.253 0.747 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.250 0.749 0.000
F60.8 Other specific personality disorders
0.250 0.750 0.000
I69 Sequelae of cerebrovascular disease
0.249 0.751 0.000
H55-H59 Other disorders of eye and adnexa
0.249 0.751 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.248 0.752 0.000
I60-I69 Cerebrovascular diseases
0.248 0.752 0.000
I71 Aortic aneurysm and dissection
0.247 0.753 0.000
F60.6 Anxious [avoidant] personality disorder
0.246 0.754 0.000
F34 Persistent mood [affective] disorders
0.246 0.754 0.000
H40.8 Other glaucoma
0.244 0.756 0.000
Q24 Other congenital malformations of heart
0.243 0.757 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.243 0.757 0.000
H53.0 Amblyopia ex anopsia
0.243 0.757 0.000
F25 Schizoaffective disorders
0.239 0.761 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.239 0.761 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.237 0.763 0.000
F99 Mental disorder, not otherwise specified
0.236 0.764 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.235 0.765 0.000
F30 Manic episode
0.234 0.766 0.000
F20.0 Paranoid schizophrenia
0.234 0.766 0.000
E65-E68 Obesity and other hyperalimentation
0.234 0.766 0.000
F60.9 Personality disorder, unspecified
0.233 0.766 0.000
F69 Unspecified disorder of adult personality and behaviour
0.233 0.767 0.000
G93.9 Disorder of brain, unspecified
0.233 0.767 0.000
F50 Eating disorders
0.232 0.768 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.230 0.770 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.230 0.770 0.000
F70-F79 Mental retardation
0.230 0.770 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.230 0.770 0.000
I67 Other cerebrovascular diseases
0.229 0.771 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.229 0.771 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.229 0.771 0.000
G93.4 Encephalopathy, unspecified
0.228 0.772 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.227 0.773 0.000
E50-E64 Other nutritional deficiencies
0.227 0.773 0.000
F32 Depressive episode
0.227 0.773 0.000
H30 Chorioretinal inflammation
0.226 0.774 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.226 0.774 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.226 0.774 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.226 0.774 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.226 0.774 0.000
Chapter XX External causes of morbidity and mortality
0.226 0.774 0.000
F34.1 Dysthymia
0.226 0.774 0.000
F17.9 Unspecified mental and behavioural disorder
0.225 0.775 0.000
F17.8 Other mental and behavioural disorders
0.225 0.775 0.000
F17.7 Residual and late-onset psychotic disorder
0.225 0.775 0.000
F17.6 Amnesic syndrome
0.225 0.775 0.000
F17.5 Psychotic disorder
0.225 0.775 0.000
F17.4 Withdrawal state with delirium
0.225 0.775 0.000
F17.3 Withdrawal state
0.225 0.775 0.000
F17.0 Acute intoxication
0.225 0.775 0.000
G31.0 Circumscribed brain atrophy
0.224 0.776 0.000
H40.0 Glaucoma suspect
0.224 0.776 0.000
F68 Other disorders of adult personality and behaviour
0.223 0.777 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.223 0.777 0.000
F65 Disorders of sexual preference
0.223 0.777 0.000
F63 Habit and impulse disorders
0.223 0.777 0.000
F61 Mixed and other personality disorders
0.223 0.777 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.223 0.777 0.000
G96 Other disorders of central nervous system
0.222 0.778 0.000
I67.1 Cerebral aneurysm, nonruptured
0.221 0.779 0.000
I69.3 Sequelae of cerebral infarction
0.220 0.780 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.220 0.780 0.000
F60.7 Dependent personality disorder
0.219 0.781 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.218 0.782 0.000
F11.2 Dependence syndrome
0.218 0.782 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.217 0.783 0.000
F60.5 Anankastic personality disorder
0.217 0.783 0.000
F60.4 Histrionic personality disorder
0.217 0.783 0.000
F60.2 Dissocial personality disorder
0.217 0.783 0.000
F60.1 Schizoid personality disorder
0.217 0.783 0.000
F60.0 Paranoid personality disorder
0.217 0.783 0.000
Q27 Other congenital malformations of peripheral vascular system
0.217 0.783 0.000
G90 Disorders of autonomic nervous system
0.217 0.783 0.000
G97.1 Other reaction to spinal and lumbar puncture
0.217 0.783 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.216 0.784 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.216 0.784 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.215 0.785 0.000
F32.1 Moderate depressive episode
0.215 0.785 0.000
H31 Other disorders of choroid
0.215 0.785 0.000
G31.1 Senile degeneration of brain, not elsewhere classified
0.215 0.785 0.000
Q24.8 Other specified congenital malformations of heart
0.215 0.785 0.000
F23 Acute and transient psychotic disorders
0.215 0.785 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.214 0.786 0.000
F22 Persistent delusional disorders
0.214 0.786 0.000
G44 Other headache syndromes
0.213 0.787 0.000
F50.0 Anorexia nervosa
0.213 0.787 0.000
H91.8 Other specified hearing loss
0.212 0.788 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.212 0.788 0.000
Q65 Congenital deformities of hip
0.212 0.788 0.000
H42 Glaucoma in diseases classified elsewhere
0.211 0.789 0.000
F80-F89 Disorders of psychological development
0.211 0.789 0.000
G70-G73 Diseases of myoneural junction and muscle
0.210 0.790 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.210 0.790 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.209 0.791 0.000
I67.8 Other specified cerebrovascular diseases
0.209 0.791 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.209 0.791 0.000
F30.9 Manic episode, unspecified
0.208 0.792 0.000
G40.8 Other epilepsy
0.208 0.792 0.000
F28 Other nonorganic psychotic disorders
0.208 0.792 0.000
F24 Induced delusional disorder
0.208 0.792 0.000
F21 Schizotypal disorder
0.208 0.792 0.000
Q35-Q37 Cleft lip and cleft palate
0.208 0.792 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.208 0.792 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.207 0.793 0.000
H40.5 Glaucoma secondary to other eye disorders
0.207 0.793 0.000
G40.5 Special epileptic syndromes
0.205 0.794 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.205 0.795 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.205 0.795 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.204 0.796 0.000
G97.8 Other postprocedural disorders of nervous system
0.204 0.796 0.000
H92 Otalgia and effusion of ear
0.203 0.797 0.000
I72.9 Aneurysm of unspecified site
0.203 0.797 0.000
F62.9 Enduring personality change, unspecified
0.203 0.797 0.000
I72.2 Aneurysm of renal artery
0.203 0.797 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.203 0.797 0.000
Q60-Q64 Congenital malformations of the urinary system
0.201 0.798 0.000
Q21 Congenital malformations of cardiac septa
0.201 0.798 0.000
F11.3 Withdrawal state
0.201 0.799 0.000
I78 Diseases of capillaries
0.201 0.799 0.000
F64 Gender identity disorders
0.200 0.799 0.000
F39 Unspecified mood [affective] disorder
0.200 0.800 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.199 0.801 0.000
Q24.5 Malformation of coronary vessels
0.199 0.801 0.000
H40.6 Glaucoma secondary to drugs
0.198 0.802 0.000
H40.4 Glaucoma secondary to eye inflammation
0.198 0.802 0.000
H40.3 Glaucoma secondary to eye trauma
0.198 0.802 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.198 0.802 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.198 0.802 0.000
G92 Toxic encephalopathy
0.197 0.803 0.000
E40-E46 Malnutrition
0.197 0.803 0.000
I72.3 Aneurysm of iliac artery
0.197 0.803 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.197 0.803 0.000
F38 Other mood [affective] disorders
0.197 0.803 0.000
H33 Retinal detachments and breaks
0.197 0.803 0.000
G96.0 Cerebrospinal fluid leak
0.196 0.803 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.196 0.804 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.195 0.805 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.195 0.805 0.000
G93.8 Other specified disorders of brain
0.195 0.805 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.194 0.806 0.000
Q80-Q89 Other congenital malformations
0.194 0.806 0.000
G97.0 Cerebrospinal fluid leak from spinal puncture
0.194 0.806 0.000
I72.0 Aneurysm of carotid artery
0.194 0.806 0.000
G81 Hemiplegia
0.194 0.806 0.000
W20-W49 Exposure to inanimate mechanical forces
0.194 0.806 0.000
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere
0.193 0.807 0.000
Q50-Q56 Congenital malformations of genital organs
0.193 0.807 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.193 0.807 0.000
Q23 Congenital malformations of aortic and mitral valves
0.193 0.807 0.000
F25.9 Schizoaffective disorder, unspecified
0.192 0.808 0.000
Q26 Congenital malformations of great veins
0.192 0.808 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.192 0.808 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.192 0.808 0.000
Q00-Q07 Congenital malformations of the nervous system
0.192 0.808 0.000
I74.5 Embolism and thrombosis of iliac artery
0.192 0.808 0.000
H91.2 Sudden idiopathic hearing loss
0.191 0.809 0.000
H91.0 Ototoxic hearing loss
0.191 0.809 0.000
H91.1 Presbycusis
0.191 0.809 0.000
I72.6 Aneurysm and dissection of vertebral artery
0.191 0.809 0.000
I72.5 Aneurysm and dissection of other precerebral arteries
0.191 0.809 0.000
I72.1 Aneurysm of artery of upper extremity
0.191 0.809 0.000
H91.3 Deaf mutism, not elsewhere classified
0.190 0.809 0.000
I71.0 Dissection of aorta [any part]
0.190 0.809 0.000
F25.0 Schizoaffective disorder, manic type
0.190 0.810 0.000
Q65.8 Other congenital deformities of hip
0.190 0.810 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.189 0.811 0.000
H55 Nystagmus and other irregular eye movements
0.189 0.811 0.000
Q25 Congenital malformations of great arteries
0.189 0.811 0.000
F11.9 Unspecified mental and behavioural disorder
0.189 0.811 0.000
F11.8 Other mental and behavioural disorders
0.189 0.811 0.000
F11.7 Residual and late-onset psychotic disorder
0.189 0.811 0.000
F11.6 Amnesic syndrome
0.189 0.811 0.000
F11.5 Psychotic disorder
0.189 0.811 0.000
F11.4 Withdrawal state with delirium
0.189 0.811 0.000
F11.1 Harmful use
0.189 0.811 0.000
F11.0 Acute intoxication
0.189 0.811 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.188 0.812 0.000
G54 Nerve root and plexus disorders
0.188 0.812 0.000
E61 Deficiency of other nutrient elements
0.188 0.812 0.000
H54 Blindness and low vision
0.188 0.812 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.187 0.813 0.000
G37 Other demyelinating diseases of central nervous system
0.187 0.813 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.186 0.813 0.000
E51 Thiamine deficiency
0.186 0.814 0.000
Q28 Other congenital malformations of circulatory system
0.185 0.815 0.000
I74.8 Embolism and thrombosis of other arteries
0.185 0.815 0.000
I00-I02 Acute rheumatic fever
0.185 0.815 0.000
F29 Unspecified nonorganic psychosis
0.185 0.815 0.000
W50-W64 Exposure to animate mechanical forces
0.185 0.815 0.000
F53 Mental and behavioural disorders associated with the puerperium, not elsewhere classified
0.184 0.815 0.000
F51 Nonorganic sleep disorders
0.184 0.815 0.000
F59 Unspecified behavioural syndromes associated with physiological disturbances and physical factors
0.184 0.815 0.000
F55 Abuse of non-dependence-producing substances
0.184 0.815 0.000
F54 Psychological and behavioural factors associated with disorders or diseases classified elsewhere
0.184 0.815 0.000
F13.2 Dependence syndrome
0.184 0.816 0.000
Q18 Other congenital malformations of face and neck
0.184 0.816 0.000
Q12 Congenital lens malformations
0.184 0.816 0.000
G43 Migraine
0.184 0.816 0.000
F20.8 Other schizophrenia
0.183 0.816 0.000
F20.6 Simple schizophrenia
0.183 0.816 0.000
F20.5 Residual schizophrenia
0.183 0.816 0.000
F20.4 Postschizophrenic depression
0.183 0.816 0.000
F20.3 Undifferentiated schizophrenia
0.183 0.816 0.000
F20.2 Catatonic schizophrenia
0.183 0.816 0.000
F20.1 Hebephrenic schizophrenia
0.183 0.816 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.183 0.816 0.000
H43-H45 Disorders of vitreous body and globe
0.183 0.817 0.000
G93.3 Postviral fatigue syndrome
0.183 0.817 0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified
0.183 0.817 0.000
E66 Obesity
0.183 0.817 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.182 0.817 0.000
V10-V19 Pedal cyclist injured in transport accident
0.182 0.818 0.000
V80-V89 Other land transport accidents
0.182 0.818 0.000
H58.8 Visual disturbances in diseases classified elsewhere
0.182 0.818 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.181 0.818 0.000
G93.7 Reye's syndrome
0.181 0.819 0.000
G90.9 Disorder of autonomic nervous system, unspecified
0.181 0.819 0.000
W75-W84 Other accidental threats to breathing
0.180 0.819 0.000
G93.6 Cerebral oedema
0.180 0.820 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.180 0.820 0.000
I77 Other disorders of arteries and arterioles
0.180 0.820 0.000
G97.9 Postprocedural disorder of nervous system, unspecified
0.180 0.820 0.000
G97.2 Intracranial hypotension following ventricular shunting
0.180 0.820 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.180 0.820 0.000
Q39 Congenital malformations of oesophagus
0.180 0.820 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.179 0.821 0.000
X10-X19 Contact with heat and hot substances
0.179 0.821 0.000
G54.4 Lumbosacral root disorders, not elsewhere classified
0.179 0.821 0.000
Q74 Other congenital malformations of limb(s)
0.179 0.821 0.000
Q67.5 Congenital deformity of spine
0.178 0.822 0.000
Q63 Other congenital malformations of kidney
0.178 0.822 0.000
F62.8 Other enduring personality changes
0.178 0.822 0.000
F62.1 Enduring personality change after psychiatric illness
0.178 0.822 0.000
F62.0 Enduring personality change after catastrophic experience
0.178 0.822 0.000
X50-X57 Overexertion, travel and privation
0.177 0.823 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.177 0.823 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.177 0.823 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.177 0.823 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.177 0.823 0.000
F34.9 Persistent mood [affective] disorder, unspecified
0.176 0.824 0.000
F34.8 Other persistent mood [affective] disorders
0.176 0.824 0.000
F34.0 Cyclothymia
0.176 0.824 0.000
G44.4 Drug-induced headache, not elsewhere classified
0.176 0.824 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.176 0.824 0.000
G93.5 Compression of brain
0.176 0.824 0.000
F20.9 Schizophrenia, unspecified
0.176 0.824 0.000
G90.0 Idiopathic peripheral autonomic neuropathy
0.175 0.825 0.000
Q24.9 Congenital malformation of the heart, unspecified
0.175 0.825 0.000
V01-V09 Pedestrian injured in transport accident
0.175 0.825 0.000
G93.0 Cerebral cysts
0.175 0.825 0.000
I66.3 Occlusion and stenosis of cerebellar arteries
0.175 0.825 0.000
Q24.6 Congenital heart block
0.174 0.826 0.000
Q24.4 Congenital subaortic stenosis
0.174 0.826 0.000
Q24.3 Pulmonary infundibular stenosis
0.174 0.826 0.000
Q24.2 Cor triatriatum
0.174 0.826 0.000
Q24.1 Levocardia
0.174 0.826 0.000
Q24.0 Dextrocardia
0.174 0.826 0.000
Q78 Other osteochondrodysplasias
0.174 0.826 0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine
0.174 0.826 0.000
Q75 Other congenital malformations of skull and face bones
0.174 0.826 0.000
Q73 Reduction defects of unspecified limb
0.174 0.826 0.000
Q72 Reduction defects of lower limb
0.174 0.826 0.000
Q71 Reduction defects of upper limb
0.174 0.826 0.000
Q70 Syndactyly
0.174 0.826 0.000
Q69 Polydactyly
0.174 0.826 0.000
Q68 Other congenital musculoskeletal deformities
0.174 0.826 0.000
G20-G26 Extrapyramidal and movement disorders
0.174 0.826 0.000
G54.9 Nerve root and plexus disorder, unspecified
0.174 0.826 0.000
G44.0 Cluster headache syndrome
0.173 0.827 0.000
I78.0 Hereditary haemorrhagic telangiectasia
0.173 0.827 0.000
Q27.3 Peripheral arteriovenous malformation
0.173 0.827 0.000
V20-V29 Motorcycle rider injured in transport accident
0.173 0.827 0.000
I70 Atherosclerosis
0.173 0.827 0.000
G70 Myasthenia gravis and other myoneural disorders
0.172 0.827 0.000
F25.8 Other schizoaffective disorders
0.172 0.828 0.000
F25.2 Schizoaffective disorder, mixed type
0.172 0.828 0.000
F13.9 Unspecified mental and behavioural disorder
0.171 0.828 0.000
F13.8 Other mental and behavioural disorders
0.171 0.828 0.000
F13.7 Residual and late-onset psychotic disorder
0.171 0.828 0.000
F13.6 Amnesic syndrome
0.171 0.828 0.000
F13.5 Psychotic disorder
0.171 0.828 0.000
F13.4 Withdrawal state with delirium
0.171 0.828 0.000
F13.3 Withdrawal state
0.171 0.828 0.000
F13.1 Harmful use
0.171 0.828 0.000
F13.0 Acute intoxication
0.171 0.828 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.171 0.828 0.000
F50.9 Eating disorder, unspecified
0.171 0.829 0.000
E00-E07 Disorders of thyroid gland
0.171 0.829 0.000
I72.8 Aneurysm of other specified arteries
0.170 0.829 0.000
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere
0.170 0.830 0.000
V98-V99 Other and unspecified transport accidents
0.169 0.831 0.000
G81.9 Hemiplegia, unspecified
0.169 0.831 0.000
F25.1 Schizoaffective disorder, depressive type
0.169 0.831 0.000
Q40 Other congenital malformations of upper alimentary tract
0.169 0.831 0.000
Q17 Other congenital malformations of ear
0.168 0.831 0.000
Q16 Congenital malformations of ear causing impairment of hearing
0.168 0.831 0.000
Q15 Other congenital malformations of eye
0.168 0.831 0.000
Q14 Congenital malformations of posterior segment of eye
0.168 0.831 0.000
Q13 Congenital malformations of anterior segment of eye
0.168 0.831 0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos
0.168 0.831 0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit
0.168 0.831 0.000
Y00-Y09 Assault
0.168 0.832 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.168 0.832 0.000
F30.8 Other manic episodes
0.168 0.832 0.000
F30.2 Mania with psychotic symptoms
0.168 0.832 0.000
F30.1 Mania without psychotic symptoms
0.168 0.832 0.000
E67 Other hyperalimentation
0.168 0.832 0.000
E68 Sequelae of hyperalimentation
0.168 0.832 0.000
G46.7 Other lacunar syndromes
0.167 0.832 0.000
F19.2 Dependence syndrome
0.167 0.833 0.000
F22.9 Persistent delusional disorder, unspecified
0.167 0.833 0.000
F50.8 Other eating disorders
0.166 0.833 0.000
F50.5 Vomiting associated with other psychological disturbances
0.166 0.833 0.000
F50.4 Overeating associated with other psychological disturbances
0.166 0.833 0.000
F50.3 Atypical bulimia nervosa
0.166 0.833 0.000
F50.2 Bulimia nervosa
0.166 0.833 0.000
F50.1 Atypical anorexia nervosa
0.166 0.833 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.166 0.834 0.000
I99 Other and unspecified disorders of circulatory system
0.166 0.834 0.000
E66.0 Obesity due to excess calories
0.165 0.835 0.000
F79 Unspecified mental retardation
0.165 0.835 0.000
F78 Other mental retardation
0.165 0.835 0.000
F73 Profound mental retardation
0.165 0.835 0.000
F72 Severe mental retardation
0.165 0.835 0.000
F71 Moderate mental retardation
0.165 0.835 0.000
F70 Mild mental retardation
0.165 0.835 0.000
F98 Other behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.165 0.835 0.000
F95 Tic disorders
0.165 0.835 0.000
F94 Disorders of social functioning with onset specific to childhood and adolescence
0.165 0.835 0.000
F93 Emotional disorders with onset specific to childhood
0.165 0.835 0.000
F92 Mixed disorders of conduct and emotions
0.165 0.835 0.000
F91 Conduct disorders
0.165 0.835 0.000
F90 Hyperkinetic disorders
0.165 0.835 0.000
K90-K93 Other diseases of the digestive system
0.165 0.835 0.000
G96.8 Other specified disorders of central nervous system
0.165 0.835 0.000
H32.8 Other chorioretinal disorders in diseases classified elsewhere
0.165 0.835 0.000
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere
0.165 0.835 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.164 0.835 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.164 0.835 0.000
I67.5 Moyamoya disease
0.164 0.835 0.000
I67.4 Hypertensive encephalopathy
0.164 0.835 0.000
I67.3 Progressive vascular leukoencephalopathy
0.164 0.835 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.164 0.836 0.000
H31.8 Other specified disorders of choroid
0.164 0.836 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.164 0.836 0.000
Q27.8 Other specified congenital malformations of peripheral vascular system
0.164 0.836 0.000
F32.8 Other depressive episodes
0.164 0.836 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.163 0.837 0.000
E63 Other nutritional deficiencies
0.163 0.837 0.000
E56 Other vitamin deficiencies
0.163 0.837 0.000
E50 Vitamin A deficiency
0.163 0.837 0.000
E60 Dietary zinc deficiency
0.163 0.837 0.000
E59 Dietary selenium deficiency
0.163 0.837 0.000
E58 Dietary calcium deficiency
0.163 0.837 0.000
E54 Ascorbic acid deficiency
0.163 0.837 0.000
E52 Niacin deficiency [pellagra]
0.163 0.837 0.000
Q99 Other chromosome abnormalities, not elsewhere classified
0.163 0.837 0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified
0.163 0.837 0.000
Q96 Turner's syndrome
0.163 0.837 0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified
0.163 0.837 0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified
0.163 0.837 0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified
0.163 0.837 0.000
Q91 Edwards' syndrome and Patau's syndrome
0.163 0.837 0.000
Q90 Down's syndrome
0.163 0.837 0.000
F30.0 Hypomania
0.163 0.837 0.000
G43.1 Migraine with aura [classical migraine]
0.163 0.837 0.000
H30.8 Other chorioretinal inflammations
0.162 0.837 0.000
H30.2 Posterior cyclitis
0.162 0.837 0.000
H30.1 Disseminated chorioretinal inflammation
0.162 0.837 0.000
H30.0 Focal chorioretinal inflammation
0.162 0.837 0.000
F14.9 Unspecified mental and behavioural disorder
0.162 0.838 0.000
F14.8 Other mental and behavioural disorders
0.162 0.838 0.000
F14.7 Residual and late-onset psychotic disorder
0.162 0.838 0.000
F14.6 Amnesic syndrome
0.162 0.838 0.000
F14.5 Psychotic disorder
0.162 0.838 0.000
F14.4 Withdrawal state with delirium
0.162 0.838 0.000
F14.3 Withdrawal state
0.162 0.838 0.000
F14.2 Dependence syndrome
0.162 0.838 0.000
F14.1 Harmful use
0.162 0.838 0.000
F14.0 Acute intoxication
0.162 0.838 0.000
F15.9 Unspecified mental and behavioural disorder
0.162 0.838 0.000
F15.8 Other mental and behavioural disorders
0.162 0.838 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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