TreeWAS – Variant ID: rs13358260

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Z72.0 Tobacco use	0.184	0.816	0.000
Z72 Problems related to lifestyle	0.129	0.871	0.000
Z70-Z76 Persons encountering health services in other circumstances	0.122	0.878	0.000
Z73 Problems related to life-management difficulty	0.114	0.886	0.000
Z75 Problems related to medical facilities and other health care	0.108	0.892	0.000
Z73.9 Problem related to life-management difficulty, unspecified	0.107	0.893	0.000
Z76 Persons encountering health services in other circumstances	0.102	0.897	0.000
N50.8 Other specified disorders of male genital organs	0.096	0.904	0.000
Z75.4 Unavailability and inaccessibility of other helping agencies	0.095	0.905	0.000
Z72.9 Problem related to lifestyle, unspecified	0.093	0.907	0.000
Z72.8 Other problems related to lifestyle	0.093	0.907	0.000
Z72.6 Gambling and betting	0.093	0.907	0.000
Z72.5 High-risk sexual behaviour	0.093	0.907	0.000
Z72.4 Inappropriate diet and eating habits	0.093	0.907	0.000
Z72.3 Lack of physical exercise	0.093	0.907	0.000
Z76.9 Persons encountering health services in unspecified circumstances	0.090	0.910	0.000
Z73.3 Stress, not elsewhere classified	0.089	0.911	0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.088	0.912	0.000
Z70 Counselling related to sexual attitude, behaviour and orientation	0.088	0.912	0.000
Z73.8 Other problems related to life-management difficulty	0.082	0.918	0.000
Z73.6 Limitation of activities due to disability	0.082	0.918	0.000
Z73.5 Social role conflict, not elsewhere classified	0.082	0.918	0.000
Z73.4 Inadequate social skills, not elsewhere classified	0.082	0.918	0.000
Z73.2 Lack of relaxation and leisure	0.082	0.918	0.000
Z73.1 Accentuation of personality traits	0.082	0.918	0.000
Z73.0 Burn-out	0.082	0.918	0.000
Z75.1 Person awaiting admission to adequate facility elsewhere	0.081	0.918	0.000
Z75.2 Other waiting period for investigation and treatment	0.081	0.919	0.000
Z74 Problems related to care-provider dependency	0.079	0.921	0.000
Z75.9 Unspecified problem related to medical facilities and other health care	0.077	0.923	0.000
Z75.8 Other problems related to medical facilities and other health care	0.077	0.923	0.000
Z75.0 Medical services not available in home	0.077	0.923	0.000
Z75.5 Holiday relief care	0.077	0.923	0.000
Z72.2 Drug use	0.076	0.924	0.000
Z75.3 Unavailability and inaccessibility of health-care facilities	0.075	0.925	0.000
Z76.5 Malingerer [conscious situation]	0.074	0.926	0.000
Z76.4 Other boarder in health-care facility	0.074	0.926	0.000
Z76.2 Health supervision and care of other healthy infant and child	0.074	0.926	0.000
Z76.1 Health supervision and care of foundling	0.074	0.926	0.000
Z76.0 Issue of repeat prescription	0.074	0.926	0.000
Z76.8 Persons encountering health services in other specified circumstances	0.072	0.927	0.000
Z76.3 Healthy person accompanying sick person	0.072	0.928	0.000
Z71.1 Person with feared complaint in whom no diagnosis is made	0.072	0.928	0.000
Z71.9 Counselling, unspecified	0.069	0.931	0.000
Z71.6 Tobacco abuse counselling	0.067	0.933	0.000
Z74.1 Need for assistance with personal care	0.065	0.935	0.000
Z71.7 Human immunodeficiency virus [HIV] counselling	0.063	0.937	0.000
Z71.5 Drug abuse counselling and surveillance	0.063	0.937	0.000
Z71.4 Alcohol abuse counselling and surveillance	0.063	0.937	0.000
Z71.0 Person consulting on behalf of another person	0.063	0.937	0.000
Z70.9 Sex counselling, unspecified	0.063	0.937	0.000
Z70.8 Other sex counselling	0.063	0.937	0.000
Z70.3 Counselling related to combined concerns regarding sexual attitude, behaviour and orientation	0.063	0.937	0.000
Z70.2 Counselling related to sexual behaviour and orientation of third party	0.063	0.937	0.000
Z70.1 Counselling related to patient's sexual behaviour and orientation	0.063	0.937	0.000
Z70.0 Counselling related to sexual attitude	0.063	0.937	0.000
Z71.2 Person consulting for explanation of investigation findings	0.062	0.938	0.000
Z60.2 Living alone	0.057	0.943	0.000
Z74.9 Problem related to care-provider dependency, unspecified	0.057	0.943	0.000
Z74.3 Need for continuous supervision	0.057	0.943	0.000
Z71.3 Dietary counselling and surveillance	0.055	0.944	0.000
Z60 Problems related to social environment	0.055	0.944	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.055	0.945	0.000
Z57 Occupational exposure to risk-factors	0.055	0.945	0.000
Z74.8 Other problems related to care-provider dependency	0.054	0.946	0.000
Z57.2 Occupational exposure to dust	0.053	0.947	0.000
Z74.2 Need for assistance at home and no other household member able to render care	0.051	0.949	0.000
Z57.5 Occupational exposure to toxic agents in other industries	0.047	0.953	0.000
Z74.0 Reduced mobility	0.045	0.955	0.000
Z58 Problems related to physical environment	0.044	0.956	0.000
Z71.8 Other specified counselling	0.044	0.956	0.000
Chapter XXI Factors influencing health status and contact with health services	0.042	0.958	0.000
Z60.9 Problem related to social environment, unspecified	0.040	0.960	0.000
Z60.8 Other problems related to social environment	0.040	0.960	0.000
Z60.5 Target of perceived adverse discrimination and persecution	0.040	0.960	0.000
Z60.4 Social exclusion and rejection	0.040	0.960	0.000
Z60.3 Acculturation difficulty	0.040	0.960	0.000
Z60.1 Atypical parenting situation	0.040	0.960	0.000
Z60.0 Problems of adjustment to life-cycle transitions	0.040	0.960	0.000
Z65 Problems related to other psychosocial circumstances	0.040	0.960	0.000
Z64 Problems related to certain psychosocial circumstances	0.040	0.960	0.000
Z62 Other problems related to upbringing	0.040	0.960	0.000
Z61 Problems related to negative life events in childhood	0.040	0.960	0.000
Z59 Problems related to housing and economic circumstances	0.040	0.960	0.000
Z55 Problems related to education and literacy	0.040	0.960	0.000
Z57.9 Occupational exposure to unspecified risk-factor	0.039	0.961	0.000
Z57.8 Occupational exposure to other risk-factors	0.039	0.961	0.000
Z57.7 Occupational exposure to vibration	0.039	0.961	0.000
Z57.6 Occupational exposure to extreme temperature	0.039	0.961	0.000
Z57.4 Occupational exposure to toxic agents in agriculture	0.039	0.961	0.000
Z57.1 Occupational exposure to radiation	0.039	0.961	0.000
Z57.0 Occupational exposure to noise	0.039	0.961	0.000
Z57.3 Occupational exposure to other air contaminants	0.039	0.961	0.000
Z63 Other problems related to primary support group, including family circumstances	0.039	0.961	0.000
Z56 Problems related to employment and unemployment	0.038	0.961	0.000
Z58.1 Exposure to air pollution	0.036	0.964	0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.032	0.968	0.000
Z63.7 Other stressful life events affecting family and household	0.032	0.968	0.000
Z58.9 Problem related to physical environment, unspecified	0.032	0.968	0.000
Z58.8 Other problems related to physical environment	0.032	0.968	0.000
Z58.7 Exposure to tobacco smoke	0.032	0.968	0.000
Z58.6 Inadequate drinking-water supply	0.032	0.968	0.000
Z58.5 Exposure to other pollution	0.032	0.968	0.000
Z58.4 Exposure to radiation	0.032	0.968	0.000
Z58.3 Exposure to soil pollution	0.032	0.968	0.000
Z58.2 Exposure to water pollution	0.032	0.968	0.000
Z58.0 Exposure to noise	0.032	0.968	0.000
Z55.9 Problems relating to education and literacy, unspecified	0.029	0.971	0.000
Z55.8 Other problems relating to education and literacy	0.029	0.971	0.000
Z55.4 Educational maladjustment and discord with teachers and classmates	0.029	0.971	0.000
Z55.3 Underachievement in school	0.029	0.971	0.000
Z55.2 Failed examinations	0.029	0.971	0.000
Z55.1 Schooling unavailable and unattainable	0.029	0.971	0.000
Z55.0 Illiteracy and low-level literacy	0.029	0.971	0.000
Z59.9 Problem relating to housing and economic circumstances, unspecified	0.029	0.971	0.000
Z59.8 Other problems relating to housing and economic circumstances	0.029	0.971	0.000
Z59.7 Insufficient social insurance and welfare support	0.029	0.971	0.000
Z59.6 Low income	0.029	0.971	0.000
Z59.5 Extreme poverty	0.029	0.971	0.000
Z59.4 Lack of adequate food	0.029	0.971	0.000
Z59.3 Problems related to living in residential institution	0.029	0.971	0.000
Z59.2 Discord with neighbours, lodgers and landlord	0.029	0.971	0.000
Z59.1 Inadequate housing	0.029	0.971	0.000
Z59.0 Homelessness	0.029	0.971	0.000
Z61.9 Negative life events in childhood, unspecified	0.029	0.971	0.000
Z61.8 Other negative life events in childhood	0.029	0.971	0.000
Z61.7 Personal frightening experience in childhood	0.029	0.971	0.000
Z61.6 Problems related to alleged physical abuse of child	0.029	0.971	0.000
Z61.5 Problems related to alleged sexual abuse of child by person outside primary support group	0.029	0.971	0.000
Z61.4 Problems related to alleged sexual abuse of child by person within primary support group	0.029	0.971	0.000
Z61.3 Events resulting in loss of self-esteem in childhood	0.029	0.971	0.000
Z61.2 Altered pattern of family relationships in childhood	0.029	0.971	0.000
Z61.1 Removal from home in childhood	0.029	0.971	0.000
Z61.0 Loss of love relationship in childhood	0.029	0.971	0.000
Z62.9 Problem related to upbringing, unspecified	0.029	0.971	0.000
Z62.8 Other specified problems related to upbringing	0.029	0.971	0.000
Z62.6 Inappropriate parental pressure and other abnormal qualities of upbringing	0.029	0.971	0.000
Z62.5 Other problems related to neglect in upbringing	0.029	0.971	0.000
Z62.4 Emotional neglect of child	0.029	0.971	0.000
Z62.3 Hostility towards and scapegoating of child	0.029	0.971	0.000
Z62.2 Institutional upbringing	0.029	0.971	0.000
Z62.1 Parental overprotection	0.029	0.971	0.000
Z62.0 Inadequate parental supervision and control	0.029	0.971	0.000
Z64.4 Discord with counsellors	0.029	0.971	0.000
Z64.3 Seeking and accepting behavioural and psychological interventions known to be hazardous and harmful	0.029	0.971	0.000
Z64.2 Seeking and accepting physical, nutritional and chemical interventions known to be hazardous and harmful	0.029	0.971	0.000
Z64.1 Problems related to multiparity	0.029	0.971	0.000
Z64.0 Problems related to unwanted pregnancy	0.029	0.971	0.000
Z65.9 Problem related to unspecified psychosocial circumstances	0.029	0.971	0.000
Z65.8 Other specified problems related to psychosocial circumstances	0.029	0.971	0.000
Z65.5 Exposure to disaster, war and other hostilities	0.029	0.971	0.000
Z65.4 Victim of crime and terrorism	0.029	0.971	0.000
Z65.3 Problems related to other legal circumstances	0.029	0.971	0.000
Z65.2 Problems related to release from prison	0.029	0.971	0.000
Z65.1 Imprisonment and other incarceration	0.029	0.971	0.000
Z65.0 Conviction in civil and criminal proceedings without imprisonment	0.029	0.971	0.000
Z63.9 Problem related to primary support group, unspecified	0.028	0.972	0.000
Z63.8 Other specified problems related to primary support group	0.028	0.972	0.000
Z63.6 Dependent relative needing care at home	0.028	0.972	0.000
Z63.5 Disruption of family by separation and divorce	0.028	0.972	0.000
Z63.3 Absence of family member	0.028	0.972	0.000
Z63.2 Inadequate family support	0.028	0.972	0.000
Z63.1 Problems in relationship with parents and in-laws	0.028	0.972	0.000
Z56.7 Other and unspecified problems related to employment	0.028	0.972	0.000
Z56.5 Uncongenial work	0.028	0.972	0.000
Z56.4 Discord with boss and workmates	0.028	0.972	0.000
Z56.3 Stressful work schedule	0.028	0.972	0.000
Z56.2 Threat of job loss	0.028	0.972	0.000
Z56.1 Change of job	0.028	0.972	0.000
Z56.0 Unemployment, unspecified	0.028	0.972	0.000
Z22 Carrier of infectious disease	0.028	0.972	0.000
N50 Other disorders of male genital organs	0.027	0.973	0.000
Z56.6 Other physical and mental strain related to work	0.027	0.973	0.000
Z63.0 Problems in relationship with spouse or partner	0.027	0.973	0.000
Z63.4 Disappearance and death of family member	0.025	0.975	0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status	0.024	0.976	0.000
Z22.5 Carrier of viral hepatitis	0.024	0.976	0.000
Z28 Immunisation not carried out	0.023	0.977	0.000
Z27 Need for immunisation against combinations of infectious diseases	0.023	0.977	0.000
Z26 Need for immunisation against other single infectious diseases	0.023	0.977	0.000
Z25 Need for immunisation against other single viral diseases	0.023	0.977	0.000
Z24 Need for immunisation against certain single viral diseases	0.023	0.977	0.000
Z23 Need for immunisation against single bacterial diseases	0.023	0.977	0.000
Z20 Contact with and exposure to communicable diseases	0.023	0.977	0.000
Z22.1 Carrier of other intestinal infectious diseases	0.022	0.978	0.000
Z22.9 Carrier of infectious disease, unspecified	0.020	0.980	0.000
Z22.8 Carrier of other infectious diseases	0.020	0.980	0.000
Z22.6 Carrier of human T-lymphotropic virus type 1 [HTLV-1] infection	0.020	0.980	0.000
Z22.4 Carrier of infections with a predominantly sexual mode of transmission	0.020	0.980	0.000
Z22.2 Carrier of diphtheria	0.020	0.980	0.000
Z22.0 Carrier of typhoid	0.020	0.980	0.000
N50.9 Disorder of male genital organs, unspecified	0.019	0.980	0.000
Z29 Need for other prophylactic measures	0.019	0.981	0.000
N50.0 Atrophy of testis	0.018	0.982	0.000
Z22.3 Carrier of other specified bacterial diseases	0.018	0.982	0.000
Z20.9 Contact with and exposure to unspecified communicable disease	0.017	0.983	0.000
Z20.8 Contact with and exposure to other communicable diseases	0.017	0.983	0.000
Z20.7 Contact with and exposure to pediculosis, acariasis and other infestations	0.017	0.983	0.000
Z20.6 Contact with and exposure to human immunodeficiency virus [HIV]	0.017	0.983	0.000
Z20.5 Contact with and exposure to viral hepatitis	0.017	0.983	0.000
Z20.4 Contact with and exposure to rubella	0.017	0.983	0.000
Z20.3 Contact with and exposure to rabies	0.017	0.983	0.000
Z20.2 Contact with and exposure to infections with a predominantly sexual mode of transmission	0.017	0.983	0.000
Z20.1 Contact with and exposure to tuberculosis	0.017	0.983	0.000
Z20.0 Contact with and exposure to intestinal infectious diseases	0.017	0.983	0.000
Z23.8 Need for immunisation against other single bacterial diseases	0.017	0.983	0.000
Z23.7 Need for immunisation against pertussis alone	0.017	0.983	0.000
Z23.6 Need for immunisation against diphtheria alone	0.017	0.983	0.000
Z23.5 Need for immunisation against tetanus alone	0.017	0.983	0.000
Z23.4 Need for immunisation against tularaemia	0.017	0.983	0.000
Z23.3 Need for immunisation against plague	0.017	0.983	0.000
Z23.2 Need for immunisation against tuberculosis [BCG]	0.017	0.983	0.000
Z23.1 Need for immunisation against typhoid-paratyphoid alone [TAB]	0.017	0.983	0.000
Z23.0 Need for immunisation against cholera alone	0.017	0.983	0.000
Z24.6 Need for immunisation against viral hepatitis	0.017	0.983	0.000
Z24.5 Need for immunisation against rubella alone	0.017	0.983	0.000
Z24.4 Need for immunisation against measles alone	0.017	0.983	0.000
Z24.3 Need for immunisation against yellow fever	0.017	0.983	0.000
Z24.2 Need for immunisation against rabies	0.017	0.983	0.000
Z24.1 Need for immunisation against arthropod-borne viral encephalitis	0.017	0.983	0.000
Z24.0 Need for immunisation against poliomyelitis	0.017	0.983	0.000
Z25.8 Need for immunisation against other specified single viral diseases	0.017	0.983	0.000
Z25.1 Need for immunisation against influenza	0.017	0.983	0.000
Z25.0 Need for immunisation against mumps alone	0.017	0.983	0.000
Z26.9 Need for immunisation against unspecified infectious disease	0.017	0.983	0.000
Z26.8 Need for immunisation against other specified single infectious diseases	0.017	0.983	0.000
Z26.0 Need for immunisation against leishmaniasis	0.017	0.983	0.000
Z27.9 Need for immunisation against unspecified combinations of infectious diseases	0.017	0.983	0.000
Z27.8 Need for immunisation against other combinations of infectious diseases	0.017	0.983	0.000
Z27.4 Need for immunisation against measles-mumps-rubella [MMR]	0.017	0.983	0.000
Z27.3 Need for immunisation against diphtheria-tetanus-pertussis with poliomyelitis [DTP + polio]	0.017	0.983	0.000
Z27.2 Need for immunisation against diphtheria-tetanus-pertussis with typhoid-paratyphoid [DTP + TAB]	0.017	0.983	0.000
Z27.1 Need for immunisation against diphtheria-tetanus-pertussis, combined [DTP]	0.017	0.983	0.000
Z27.0 Need for immunisation against cholera with typhoid-paratyphoid [cholera + TAB]	0.017	0.983	0.000
Z28.9 Immunisation not carried out for unspecified reason	0.017	0.983	0.000
Z28.8 Immunisation not carried out for other reasons	0.017	0.983	0.000
Z28.2 Immunisation not carried out because of patient's decision for other and unspecified reasons	0.017	0.983	0.000
Z28.1 Immunisation not carried out because of patient's decision for reasons of belief or group pressure	0.017	0.983	0.000
Z28.0 Immunisation not carried out because of contraindication	0.017	0.983	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.000	0.983	0.017
H65 Nonsuppurative otitis media	0.000	0.983	0.017
H65-H75 Diseases of middle ear and mastoid	0.000	0.984	0.016
F33.9 Recurrent depressive disorder, unspecified	0.016	0.984	0.000
Z29.0 Isolation	0.015	0.985	0.000
H71 Cholesteatoma of middle ear	0.000	0.985	0.015
N50.1 Vascular disorders of male genital organs	0.015	0.985	0.000
H66 Suppurative and unspecified otitis media	0.000	0.986	0.014
H65.4 Other chronic nonsuppurative otitis media	0.000	0.986	0.014
Z29.9 Prophylactic measure, unspecified	0.014	0.986	0.000
H74 Other disorders of middle ear and mastoid	0.000	0.986	0.014
H73 Other disorders of tympanic membrane	0.000	0.986	0.014
Z29.8 Other specified prophylactic measures	0.013	0.986	0.000
F33 Recurrent depressive disorder	0.013	0.987	0.000
H65.2 Chronic serous otitis media	0.000	0.987	0.013
H66.9 Otitis media, unspecified	0.000	0.987	0.013
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.013	0.987	0.000
H70 Mastoiditis and related conditions	0.000	0.988	0.012
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.012	0.988	0.000
H73.8 Other specified disorders of tympanic membrane	0.000	0.988	0.012
H65.1 Other acute nonsuppurative otitis media	0.000	0.988	0.012
H65.0 Acute serous otitis media	0.000	0.988	0.012
Z29.2 Other prophylactic chemotherapy	0.012	0.988	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.000	0.988	0.012
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.988	0.012
H68 Eustachian salpingitis and obstruction	0.000	0.988	0.012
H67 Otitis media in diseases classified elsewhere	0.000	0.988	0.012
H74.3 Other acquired abnormalities of ear ossicles	0.000	0.988	0.012
H72 Perforation of tympanic membrane	0.000	0.988	0.012
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.012	0.988	0.000
H66.3 Other chronic suppurative otitis media	0.000	0.988	0.011
Y42.7 Androgens and anabolic congeners	0.012	0.988	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.011	0.989	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.011	0.989	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.011	0.989	0.000
H69 Other disorders of Eustachian tube	0.000	0.989	0.011
F30-F39 Mood [affective] disorders	0.011	0.989	0.000
Y57 Other and unspecified drugs and medicaments	0.011	0.989	0.000
Y57.9 Drug or medicament, unspecified	0.011	0.989	0.000
Z29.1 Prophylactic immunotherapy	0.011	0.989	0.000
F32 Depressive episode	0.011	0.989	0.000
H66.4 Suppurative otitis media, unspecified	0.000	0.989	0.010
H66.2 Chronic atticoantral suppurative otitis media	0.000	0.989	0.010
H66.1 Chronic tubotympanic suppurative otitis media	0.000	0.989	0.010
H66.0 Acute suppurative otitis media	0.000	0.989	0.010
Z72.1 Alcohol use	0.011	0.989	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.010	0.990	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.010	0.990	0.000
Y40 Systemic antibiotics	0.010	0.990	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.000	0.990	0.010
H74.2 Discontinuity and dislocation of ear ossicles	0.000	0.990	0.010
H74.1 Adhesive middle ear disease	0.000	0.990	0.010
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.010	0.990	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.010	0.990	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.000	0.990	0.010
H73.1 Chronic myringitis	0.000	0.990	0.010
H73.0 Acute myringitis	0.000	0.990	0.010
F30 Manic episode	0.010	0.990	0.000
F32.1 Moderate depressive episode	0.010	0.990	0.000
F32.3 Severe depressive episode with psychotic symptoms	0.010	0.990	0.000
H74.4 Polyp of middle ear	0.000	0.990	0.010
H74.0 Tympanosclerosis	0.000	0.990	0.010
Y41 Other systemic anti-infectives and antiparasitics	0.010	0.990	0.000
Y48 Anaesthetics and therapeutic gases	0.010	0.990	0.000
H70.9 Mastoiditis, unspecified	0.000	0.990	0.009
F33.8 Other recurrent depressive disorders	0.009	0.990	0.000
F33.4 Recurrent depressive disorder, currently in remission	0.009	0.990	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.009	0.990	0.000
F32.2 Severe depressive episode without psychotic symptoms	0.009	0.990	0.000
Y45.1 Salicylates	0.009	0.990	0.000
Y52 Agents primarily affecting the cardiovascular system	0.009	0.991	0.000
Y42.9 Other and unspecified hormone antagonists	0.009	0.991	0.000
Y42.4 Oral contraceptives	0.009	0.991	0.000
Y42.2 Antithyroid drugs	0.009	0.991	0.000
Y42.1 Thyroid hormones and substitutes	0.009	0.991	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.009	0.991	0.000
Y40.0 Penicillins	0.009	0.991	0.000
H70.8 Other mastoiditis and related conditions	0.000	0.991	0.009
H70.2 Petrositis	0.000	0.991	0.009
H70.1 Chronic mastoiditis	0.000	0.991	0.009
H70.0 Acute mastoiditis	0.000	0.991	0.009
I20.0 Unstable angina	0.009	0.991	0.000
F30.9 Manic episode, unspecified	0.009	0.991	0.000
H72.0 Central perforation of tympanic membrane	0.000	0.991	0.009
Y59 Other and unspecified vaccines and biological substances	0.009	0.991	0.000
Y58 Bacterial vaccines	0.009	0.991	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.009	0.991	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.009	0.991	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.009	0.991	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.009	0.991	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.009	0.991	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.009	0.991	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.009	0.991	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.009	0.991	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.009	0.991	0.000
F32.8 Other depressive episodes	0.009	0.991	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.000	0.991	0.009
H67.1 Otitis media in viral diseases classified elsewhere	0.000	0.991	0.009
H67.0 Otitis media in bacterial diseases classified elsewhere	0.000	0.991	0.009
H68.1 Obstruction of Eustachian tube	0.000	0.991	0.009
H68.0 Eustachian salpingitis	0.000	0.991	0.009
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.991	0.009
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.000	0.991	0.009
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.009	0.991	0.000
Y40.5 Aminoglycosides	0.009	0.991	0.000
H72.2 Other marginal perforations of tympanic membrane	0.000	0.991	0.008
H72.1 Attic perforation of tympanic membrane	0.000	0.991	0.008
Y45.0 Opioids and related analgesics	0.009	0.991	0.000
Y54.3 Benzothiadiazine derivatives	0.008	0.991	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.000	0.991	0.009
Y54.5 Other diuretics	0.008	0.991	0.000
Y45.2 Propionic acid derivatives	0.008	0.991	0.000
Y44 Agents primarily affecting blood constituents	0.008	0.991	0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.008	0.992	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.008	0.992	0.000
Y45.5 4-Aminophenol derivatives	0.008	0.992	0.000
Y45.4 Antirheumatics	0.008	0.992	0.000
H69.9 Eustachian tube disorder, unspecified	0.000	0.992	0.008
F39 Unspecified mood [affective] disorder	0.008	0.992	0.000
F34 Persistent mood [affective] disorders	0.008	0.992	0.000
Y45.8 Other analgesics and antipyretics	0.008	0.992	0.000
H69.0 Patulous Eustachian tube	0.000	0.992	0.008
F38 Other mood [affective] disorders	0.008	0.992	0.000
Y57.7 Vitamins, not elsewhere classified	0.008	0.992	0.000
Y57.6 Other diagnostic agents	0.008	0.992	0.000
Y57.4 Pharmaceutical excipients	0.008	0.992	0.000
Y57.3 Alcohol deterrents	0.008	0.992	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.008	0.992	0.000
Y57.1 Lipotropic drugs	0.008	0.992	0.000
Y57.0 Appetite depressants [anorectics]	0.008	0.992	0.000
F30.2 Mania with psychotic symptoms	0.008	0.992	0.000
Y57.8 Other drugs and medicaments	0.008	0.992	0.000
H65.3 Chronic mucoid otitis media	0.000	0.992	0.008
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.008	0.992	0.000
Z00-Z13 Persons encountering health services for examination and investigation	0.008	0.992	0.000
Y40.3 Macrolides	0.008	0.992	0.000
Y52.1 Calcium-channel blockers	0.008	0.992	0.000
Y54.9 Mineral salts, not elsewhere classified	0.008	0.992	0.000
Y54.8 Agents affecting uric acid metabolism	0.008	0.992	0.000
Y54.7 Agents affecting calcification	0.008	0.992	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.008	0.992	0.000
Y54.4 Loop [high-ceiling] diuretics	0.008	0.992	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.008	0.992	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.008	0.992	0.000
Y54.0 Mineralocorticoids	0.008	0.992	0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.008	0.992	0.000
Y40.7 Antifungal antibiotics, systemically used	0.008	0.992	0.000
Y40.6 Rifamycins	0.008	0.992	0.000
Y40.4 Tetracyclines	0.008	0.992	0.000
Y40.2 Chloramphenicol group	0.008	0.992	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.008	0.992	0.000
F30.0 Hypomania	0.008	0.992	0.000
H72.8 Other perforations of tympanic membrane	0.000	0.992	0.008
Y48.3 Local anaesthetics	0.008	0.992	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.007	0.992	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.007	0.992	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.007	0.992	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.007	0.992	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.007	0.992	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.007	0.992	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.007	0.992	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.007	0.992	0.000
Y51.0 Anticholinesterase agents	0.007	0.992	0.000
Z08 Follow-up examination after treatment for malignant neoplasm	0.008	0.992	0.000
F30.8 Other manic episodes	0.007	0.992	0.000
F30.1 Mania without psychotic symptoms	0.007	0.992	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.007	0.992	0.000
H69.8 Other specified disorders of Eustachian tube	0.000	0.993	0.007
Y40.9 Systemic antibiotic, unspecified	0.007	0.993	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.007	0.993	0.000
Y41.5 Antiviral drugs	0.007	0.993	0.000
Y41.4 Anthelminthics	0.007	0.993	0.000
Y41.3 Other antiprotozoal drugs	0.007	0.993	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.007	0.993	0.000
Y41.1 Antimycobacterial drugs	0.007	0.993	0.000
Y41.0 Sulphonamides	0.007	0.993	0.000
Y48.5 Therapeutic gases	0.007	0.993	0.000
Y48.4 Anaesthetic, unspecified	0.007	0.993	0.000
Y48.2 Other and unspecified general anaesthetics	0.007	0.993	0.000
Y48.1 Parenteral anaesthetics	0.007	0.993	0.000
Y48.0 Inhaled anaesthetics	0.007	0.993	0.000
Y42.5 Other oestrogens and progestogens	0.007	0.993	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.007	0.993	0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.007	0.993	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.007	0.993	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.007	0.993	0.000
Y52.7 Peripheral vasodilators	0.007	0.993	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.007	0.993	0.000
Z02 Examination and encounter for administrative purposes	0.007	0.993	0.000
F32.0 Mild depressive episode	0.007	0.993	0.000
Y57.5 X-ray contrast media	0.007	0.993	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.007	0.993	0.000
Y46.8 Antispasticity drugs	0.007	0.993	0.000
Y46.7 Anti-Parkinsonism drugs	0.007	0.993	0.000
Y46.6 Other and unspecified antiepileptics	0.007	0.993	0.000
Y46.5 Valproic acid	0.007	0.993	0.000
Y46.4 Iminostilbenes	0.007	0.993	0.000
Y46.3 Deoxybarbiturates	0.007	0.993	0.000
Y46.2 Hydantoin derivatives	0.007	0.993	0.000
Y46.1 Oxazolidinediones	0.007	0.993	0.000
Y46.0 Succinimides	0.007	0.993	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.007	0.993	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.007	0.993	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.007	0.993	0.000
Y47.4 Bromine compounds	0.007	0.993	0.000
Y47.3 Paraldehyde	0.007	0.993	0.000
Y47.2 Chloral derivatives	0.007	0.993	0.000
Y47.1 Benzodiazepines	0.007	0.993	0.000
Y47.0 Barbiturates, not elsewhere classified	0.007	0.993	0.000
Y49.9 Psychotropic drug, unspecified	0.007	0.993	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.007	0.993	0.000
Y49.7 Psychostimulants with abuse potential	0.007	0.993	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.007	0.993	0.000
Y49.5 Other antipsychotics and neuroleptics	0.007	0.993	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.007	0.993	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.007	0.993	0.000
Y49.2 Other and unspecified antidepressants	0.007	0.993	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.007	0.993	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.007	0.993	0.000
Y50.9 Central nervous system stimulant, unspecified	0.007	0.993	0.000
Y50.8 Other central nervous system stimulants	0.007	0.993	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.007	0.993	0.000
Y50.1 Opioid receptor antagonists	0.007	0.993	0.000
Y50.0 Analeptics	0.007	0.993	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.007	0.993	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.007	0.993	0.000
Y55.5 Anticommon cold drugs	0.007	0.993	0.000
Y55.4 Expectorants	0.007	0.993	0.000
Y55.3 Antitussives	0.007	0.993	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.007	0.993	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.007	0.993	0.000
Y55.0 Oxytocic drugs	0.007	0.993	0.000
Y58.9 Other and unspecified bacterial vaccines	0.007	0.993	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.007	0.993	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.007	0.993	0.000
Y58.5 Diphtheria vaccine	0.007	0.993	0.000
Y58.4 Tetanus vaccine	0.007	0.993	0.000
Y58.3 Plague vaccine	0.007	0.993	0.000
Y58.2 Cholera vaccine	0.007	0.993	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.007	0.993	0.000
Y58.0 BCG vaccine	0.007	0.993	0.000
Y59.9 Vaccine or biological substance, unspecified	0.007	0.993	0.000
Y59.8 Other specified vaccines and biological substances	0.007	0.993	0.000
Y59.3 Immunoglobulin	0.007	0.993	0.000
Y59.2 Protozoal vaccines	0.007	0.993	0.000
Y59.1 Rickettsial vaccines	0.007	0.993	0.000
Y59.0 Viral vaccines	0.007	0.993	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.007	0.993	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.007	0.993	0.000
Y53.7 Emetics	0.007	0.993	0.000
Y53.6 Antidiarrhoeal drugs	0.007	0.993	0.000
Y53.5 Digestants	0.007	0.993	0.000
Y53.4 Other laxatives	0.007	0.993	0.000
Y53.3 Saline and osmotic laxatives	0.007	0.993	0.000
Y53.2 Stimulant laxatives	0.007	0.993	0.000
Y53.0 Histamine H2-receptor antagonists	0.007	0.993	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.007	0.993	0.000
Z01.9 Special examination, unspecified	0.007	0.993	0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm	0.007	0.993	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.006	0.993	0.000
Y56.9 Topical agent, unspecified	0.006	0.993	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations