TreeWAS – Variant ID: rs1351164

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K22.7 Barrett's oesophagus	0.077	0.923	0.000
K22.8 Other specified diseases of oesophagus	0.076	0.924	0.000
K22 Other diseases of oesophagus	0.073	0.927	0.000
K22.0 Achalasia of cardia	0.070	0.930	0.000
F99 Mental disorder, not otherwise specified	0.000	0.932	0.068
K22.1 Ulcer of oesophagus	0.064	0.936	0.000
K22.4 Dyskinesia of oesophagus	0.060	0.940	0.000
K22.3 Perforation of oesophagus	0.056	0.944	0.000
K22.5 Diverticulum of oesophagus, acquired	0.049	0.951	0.000
K22.9 Disease of oesophagus, unspecified	0.049	0.951	0.000
C73 Malignant neoplasm of thyroid gland	0.040	0.960	0.000
F99-F99 Unspecified mental disorder	0.000	0.971	0.029
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.028	0.972	0.000
C74 Malignant neoplasm of adrenal gland	0.024	0.976	0.000
C75 Malignant neoplasm of other endocrine glands and related structures	0.023	0.976	0.000
S02.20 Fracture of nasal bones (closed)	0.023	0.977	0.000
S02.50 Fracture of tooth (closed)	0.022	0.977	0.000
S02.2 Fracture of nasal bones	0.022	0.978	0.000
S02.5 Fracture of tooth	0.022	0.978	0.000
S02 Fracture of skull and facial bones	0.021	0.979	0.000
C74.0 Cortex of adrenal gland	0.020	0.980	0.000
C74.9 Adrenal gland, unspecified	0.020	0.980	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.020	0.980	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.019	0.981	0.000
C75.0 Parathyroid gland	0.019	0.981	0.000
C75.9 Endocrine gland, unspecified	0.019	0.981	0.000
S02.1 Fracture of base of skull	0.019	0.981	0.000
C74.1 Medulla of adrenal gland	0.018	0.982	0.000
S02.10 Fracture of base of skull (closed)	0.017	0.983	0.000
C75.8 Pluriglandular involvement, unspecified	0.017	0.983	0.000
C75.5 Aortic body and other paraganglia	0.017	0.983	0.000
C75.4 Carotid body	0.017	0.983	0.000
C75.3 Pineal gland	0.017	0.983	0.000
C75.2 Craniopharyngeal duct	0.017	0.983	0.000
C75.1 Pituitary gland	0.017	0.983	0.000
S02.0 Fracture of vault of skull	0.016	0.983	0.000
S02.7 Multiple fractures involving skull and facial bones	0.016	0.984	0.000
S02.21 Fracture of nasal bones (open)	0.016	0.984	0.000
S02.51 Fracture of tooth (open)	0.016	0.984	0.000
S02.8 Fractures of other skull and facial bones	0.015	0.985	0.000
S02.3 Fracture of orbital floor	0.015	0.985	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.014	0.985	0.000
S02.11 Fracture of base of skull (open)	0.014	0.986	0.000
S02.4 Fracture of malar and maxillary bones	0.013	0.987	0.000
S02.00 Fracture of vault of skull (closed)	0.013	0.987	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.012	0.988	0.000
S02.01 Fracture of vault of skull (open)	0.012	0.988	0.000
S02.71 Multiple fractures involving skull and facial bones (open)	0.012	0.988	0.000
S02.81 Fractures of other skull and facial bones (open)	0.011	0.989	0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome	0.010	0.989	0.001
S02.31 Fracture of orbital floor (open)	0.011	0.989	0.000
S02.6 Fracture of mandible	0.011	0.989	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.011	0.989	0.000
S02.30 Fracture of orbital floor (closed)	0.010	0.989	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.010	0.990	0.000
C25.0 Head of pancreas	0.009	0.991	0.000
C25.9 Pancreas, unspecified	0.009	0.991	0.000
L50.9 Urticaria, unspecified	0.000	0.991	0.009
S02.61 Fracture of mandible (open)	0.008	0.992	0.000
C25 Malignant neoplasm of pancreas	0.008	0.992	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.008	0.992	0.000
C25.3 Pancreatic duct	0.007	0.993	0.000
C25.2 Tail of pancreas	0.006	0.993	0.000
C25.8 Overlapping lesion of pancreas	0.006	0.994	0.000
C25.7 Other parts of pancreas	0.006	0.994	0.000
C25.4 Endocrine pancreas	0.006	0.994	0.000
Z80.4 Family history of malignant neoplasm of genital organs	0.006	0.994	0.000
Z80.0 Family history of malignant neoplasm of digestive organs	0.005	0.995	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.000	0.995	0.005
G44.2 Tension-type headache	0.000	0.995	0.005
R56.8 Other and unspecified convulsions	0.005	0.995	0.000
L50 Urticaria	0.000	0.995	0.005
Z80 Family history of malignant neoplasm	0.005	0.995	0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene	0.005	0.995	0.000
Z80.8 Family history of malignant neoplasm of other organs or systems	0.005	0.995	0.000
C25.1 Body of pancreas	0.004	0.996	0.000
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs	0.004	0.996	0.000
L50.1 Idiopathic urticaria	0.000	0.996	0.004
H02.0 Entropion and trichiasis of eyelid	0.000	0.996	0.004
Z80.6 Family history of leukaemia	0.004	0.996	0.000
C78.0 Secondary malignant neoplasm of lung	0.004	0.996	0.000
K13.7 Other and unspecified lesions of oral mucosa	0.000	0.996	0.004
I60.9 Subarachnoid haemorrhage, unspecified	0.004	0.996	0.000
S02.60 Fracture of mandible (closed)	0.003	0.996	0.001
L50.6 Contact urticaria	0.000	0.996	0.004
L50.5 Cholinergic urticaria	0.000	0.996	0.004
L50.4 Vibratory urticaria	0.000	0.996	0.004
L50.3 Dermatographic urticaria	0.000	0.996	0.004
L50.2 Urticaria due to cold and heat	0.000	0.996	0.004
L50.8 Other urticaria	0.000	0.997	0.003
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung	0.003	0.997	0.000
L50.0 Allergic urticaria	0.000	0.997	0.003
Z80.5 Family history of malignant neoplasm of urinary tract	0.003	0.997	0.000
Z80.9 Family history of malignant neoplasm, unspecified	0.003	0.997	0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues	0.003	0.997	0.000
M79.18 Myalgia (Other)	0.000	0.997	0.003
K44 Diaphragmatic hernia	0.003	0.997	0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene	0.003	0.997	0.000
H57 Other disorders of eye and adnexa	0.003	0.997	0.000
H57.9 Disorder of eye and adnexa, unspecified	0.003	0.997	0.000
Z83.5 Family history of eye and ear disorders	0.000	0.997	0.003
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities	0.000	0.997	0.003
O03.9 Complete or unspecified, without complication	0.003	0.997	0.000
E73.9 Lactose intolerance, unspecified	0.002	0.998	0.000
Q18.1 Preauricular sinus and cyst	0.002	0.998	0.000
K22.2 Oesophageal obstruction	0.002	0.998	0.000
M25.54 Pain in joint (Hand)	0.002	0.998	0.000
H57.8 Other specified disorders of eye and adnexa	0.002	0.998	0.000
H57.0 Anomalies of pupillary function	0.002	0.998	0.000
M89.9 Disorder of bone, unspecified	0.000	0.998	0.002
H58.8 Visual disturbances in diseases classified elsewhere	0.002	0.998	0.000
G45.4 Transient global amnesia	0.002	0.998	0.000
M89.98 Disorder of bone, unspecified (Other)	0.000	0.998	0.002
H57.1 Ocular pain	0.002	0.998	0.000
M34.8 Other forms of systemic sclerosis	0.002	0.998	0.000
L51 Erythema multiforme	0.000	0.998	0.002
L50-L54 Urticaria and erythema	0.000	0.998	0.002
K44.1 Diaphragmatic hernia with gangrene	0.002	0.998	0.000
H50.9 Strabismus, unspecified	0.000	0.998	0.002
J32.2 Chronic ethmoidal sinusitis	0.000	0.998	0.002
L51.1 Bullous erythema multiforme	0.000	0.998	0.002
I60.4 Subarachnoid haemorrhage from basilar artery	0.002	0.998	0.000
R56 Convulsions, not elsewhere classified	0.002	0.998	0.000
D10.3 Other and unspecified parts of mouth	0.000	0.998	0.002
Q18 Other congenital malformations of face and neck	0.002	0.998	0.000
M34.9 Systemic sclerosis, unspecified	0.002	0.998	0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.002	0.998	0.000
N99.0 Postprocedural renal failure	0.002	0.998	0.000
J02.9 Acute pharyngitis, unspecified	0.002	0.998	0.000
M79.19 Myalgia (Site unspecified)	0.000	0.998	0.002
L51.9 Erythema multiforme, unspecified	0.000	0.998	0.002
M89.94 Disorder of bone, unspecified (Hand)	0.000	0.998	0.002
N64.8 Other specified disorders of breast	0.002	0.998	0.000
Q18.0 Sinus, fistula and cyst of branchial cleft	0.002	0.998	0.000
Z80.3 Family history of malignant neoplasm of breast	0.002	0.998	0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.002	0.998	0.000
M47.99 Spondylosis, unspecified (Site unspecified)	0.000	0.998	0.002
Q12.0 Congenital cataract	0.002	0.998	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.002	0.998	0.000
K08.8 Other specified disorders of teeth and supporting structures	0.000	0.998	0.002
L52 Erythema nodosum	0.000	0.998	0.002
H55-H59 Other disorders of eye and adnexa	0.002	0.998	0.000
M89.99 Disorder of bone, unspecified (Site unspecified)	0.000	0.998	0.002
M89.92 Disorder of bone, unspecified (Upper arm)	0.000	0.998	0.002
M89.91 Disorder of bone, unspecified (Shoulder region)	0.000	0.998	0.002
M89.90 Disorder of bone, unspecified (Multiple sites)	0.000	0.998	0.002
K14.0 Glossitis	0.000	0.998	0.002
L51.8 Other erythema multiforme	0.000	0.998	0.002
L51.2 Toxic epidermal necrolysis [Lyell]	0.000	0.998	0.002
L51.0 Nonbullous erythema multiforme	0.000	0.998	0.002
I60 Subarachnoid haemorrhage	0.002	0.998	0.000
L54 Erythema in diseases classified elsewhere	0.000	0.998	0.002
M41.9 Scoliosis, unspecified	0.002	0.998	0.000
M34 Systemic sclerosis	0.002	0.998	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.002	0.998	0.000
D68.0 Von Willebrand's disease	0.002	0.998	0.000
R56.0 Febrile convulsions	0.002	0.998	0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.000	0.998	0.002
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.002	0.998	0.000
M79.1 Myalgia	0.000	0.998	0.002
Q18.9 Congenital malformation of face and neck, unspecified	0.002	0.998	0.000
Q18.8 Other specified congenital malformations of face and neck	0.002	0.998	0.000
Q18.7 Microcheilia	0.002	0.998	0.000
Q18.6 Macrocheilia	0.002	0.998	0.000
Q18.5 Microstomia	0.002	0.998	0.000
Q18.4 Macrostomia	0.002	0.998	0.000
Q18.3 Webbing of neck	0.002	0.998	0.000
Q18.2 Other branchial cleft malformations	0.002	0.998	0.000
H58.9 Other specified disorders of eye and adnexa in diseases classified elsewhere	0.002	0.998	0.000
H58.1 Visual disturbances in diseases classified elsewhere	0.002	0.998	0.000
H58.0 Anomalies of pupillary function in diseases classified elsewhere	0.002	0.998	0.000
H55 Nystagmus and other irregular eye movements	0.002	0.998	0.000
M41.92 Scoliosis, unspecified (Cervical region)	0.002	0.998	0.000
M79.15 Myalgia (Pelvic region and thigh)	0.000	0.998	0.002
M34.1 CR(E)ST syndrome	0.002	0.998	0.000
Q12 Congenital lens malformations	0.002	0.998	0.000
M41.94 Scoliosis, unspecified (Thoracic region)	0.002	0.998	0.000
D68.8 Other specified coagulation defects	0.002	0.998	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.000	0.998	0.002
K92.2 Gastro-intestinal haemorrhage, unspecified	0.002	0.998	0.000
M34.0 Progressive systemic sclerosis	0.002	0.998	0.000
M62.80 Other specified disorders of muscle (Multiple sites)	0.002	0.998	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.000	0.998	0.001
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.002	0.998	0.000
H59.9 Postprocedural disorder of eye and adnexa, unspecified	0.002	0.998	0.000
Z83.3 Family history of diabetes mellitus	0.000	0.998	0.002
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.002	0.998	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.002	0.998	0.000
W10.8 Other specified place	0.002	0.998	0.000
I35.0 Aortic (valve) stenosis	0.002	0.998	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.002	0.998	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.002	0.998	0.000
N83.0 Follicular cyst of ovary	0.000	0.998	0.002
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.002	0.998	0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.002	0.998	0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.000	0.998	0.002
L54.8 Erythema in other diseases classified elsewhere	0.000	0.998	0.001
L54.0 Erythema marginatum in acute rheumatic fever	0.000	0.998	0.001
M62.83 Other specified disorders of muscle (Forearm)	0.002	0.998	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.001	0.998	0.000
M50.0 Cervical disk disorder with myelopathy	0.000	0.998	0.002
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.002	0.998	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.000	0.998	0.001
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.000	0.998	0.002
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.002	0.998	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.998	0.002
M79.17 Myalgia (Ankle and foot)	0.000	0.998	0.001
M79.14 Myalgia (Hand)	0.000	0.998	0.001
M79.13 Myalgia (Forearm)	0.000	0.998	0.001
M79.12 Myalgia (Upper arm)	0.000	0.998	0.001
M50.2 Other cervical disk displacement	0.000	0.998	0.002
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.000	0.998	0.002
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.002	0.998	0.000
Q15 Other congenital malformations of eye	0.001	0.998	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.002	0.998	0.000
H50.5 Heterophoria	0.000	0.998	0.002
K11.6 Mucocele of salivary gland	0.002	0.998	0.000
M62.8 Other specified disorders of muscle	0.002	0.998	0.000
Q12.9 Congenital lens malformation, unspecified	0.001	0.998	0.000
Q12.8 Other congenital lens malformations	0.001	0.998	0.000
Q12.4 Spherophakia	0.001	0.998	0.000
Q12.3 Congenital aphakia	0.001	0.998	0.000
Q12.2 Coloboma of lens	0.001	0.998	0.000
Q12.1 Congenital displaced lens	0.001	0.998	0.000
Q15.0 Congenital glaucoma	0.001	0.998	0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.002	0.998	0.000
M62.81 Other specified disorders of muscle (Shoulder region)	0.001	0.998	0.000
M96.8 Other postprocedural musculoskeletal disorders	0.000	0.998	0.001
M79.10 Myalgia (Multiple sites)	0.000	0.998	0.001
M79.11 Myalgia (Shoulder region)	0.000	0.998	0.001
S12.10 Fracture of second cervical vertebra (closed)	0.001	0.998	0.000
H59.0 Vitreous syndrome following cataract surgery	0.001	0.998	0.000
H61.9 Disorder of external ear, unspecified	0.001	0.999	0.000
K74.3 Primary biliary cirrhosis	0.001	0.999	0.000
H50 Other strabismus	0.000	0.999	0.001
S92.30 Fracture of metatarsal bone (closed)	0.000	0.999	0.001
H50.2 Vertical strabismus	0.000	0.999	0.001
Z97.4 Presence of external hearing-aid	0.000	0.999	0.001
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.001	0.999	0.000
D68.6 Other Thrombophilia	0.001	0.999	0.000
M96.0 Pseudarthrosis after fusion or arthrodesis	0.000	0.999	0.001
Z83.6 Family history of diseases of the respiratory system	0.000	0.999	0.001
Q16 Congenital malformations of ear causing impairment of hearing	0.001	0.999	0.000
Q14 Congenital malformations of posterior segment of eye	0.001	0.999	0.000
Q13 Congenital malformations of anterior segment of eye	0.001	0.999	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.001	0.999	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.001	0.999	0.000
I60.8 Other subarachnoid haemorrhage	0.001	0.999	0.000
Y40.9 Systemic antibiotic, unspecified	0.000	0.999	0.001
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.001	0.999	0.000
M62.87 Other specified disorders of muscle (Ankle and foot)	0.001	0.999	0.000
M62.84 Other specified disorders of muscle (Hand)	0.001	0.999	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.001	0.999	0.000
K25.3 Acute without haemorrhage or perforation	0.001	0.999	0.000
Q15.9 Congenital malformation of eye, unspecified	0.001	0.999	0.000
Q15.8 Other specified congenital malformations of eye	0.001	0.999	0.000
Q17 Other congenital malformations of ear	0.001	0.999	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.000	0.999	0.001
M62.82 Other specified disorders of muscle (Upper arm)	0.001	0.999	0.000
E04.9 Non-toxic goitre, unspecified	0.001	0.999	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.001	0.999	0.000
Z83 Family history of other specific disorders	0.000	0.999	0.001
H50.8 Other specified strabismus	0.000	0.999	0.001
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.000	0.999	0.001
Z83.4 Family history of other endocrine, nutritional and metabolic diseases	0.000	0.999	0.001
M13.89 Other specified arthritis (Site unspecified)	0.001	0.999	0.000
E21.0 Primary hyperparathyroidism	0.000	0.999	0.001
G51.0 Bell's palsy	0.001	0.999	0.000
T02.40 Fractures involving multiple regions of both upper limbs (closed)	0.001	0.999	0.000
H50.4 Other and unspecified heterotropia	0.000	0.999	0.001
Q10.0 Congenital ptosis	0.001	0.999	0.000
S13.4 Sprain and strain of cervical spine	0.001	0.999	0.000
I35 Nonrheumatic aortic valve disorders	0.001	0.999	0.000
H50.6 Mechanical strabismus	0.000	0.999	0.001
H50.3 Intermittent heterotropia	0.000	0.999	0.001
I86.8 Varicose veins of other specified sites	0.001	0.999	0.000
N99.3 Prolapse of vaginal vault after hysterectomy	0.001	0.999	0.000
Q10.7 Congenital malformation of orbit	0.001	0.999	0.000
Q10.6 Other congenital malformations of lachrymal apparatus	0.001	0.999	0.000
Q10.5 Congenital stenosis and stricture of lachrymal duct	0.001	0.999	0.000
Q10.4 Absence and agenesis of lachrymal apparatus	0.001	0.999	0.000
Q10.3 Other congenital malformations of eyelid	0.001	0.999	0.000
Q10.2 Congenital entropion	0.001	0.999	0.000
Q10.1 Congenital ectropion	0.001	0.999	0.000
Q51.4 Unicornate uterus	0.001	0.999	0.000
S12.1 Fracture of second cervical vertebra	0.001	0.999	0.000
S12.20 Fracture of other specified cervical vertebra (closed)	0.001	0.999	0.000
J98.4 Other disorders of lung	0.000	0.999	0.001
M87.9 Osteonecrosis, unspecified	0.000	0.999	0.001
Q11.3 Macrophthalmos	0.001	0.999	0.000
Q11.2 Microphthalmos	0.001	0.999	0.000
Q11.1 Other anophthalmos	0.001	0.999	0.000
Q11.0 Cystic eyeball	0.001	0.999	0.000
Q13.9 Congenital malformation of anterior segment of eye, unspecified	0.001	0.999	0.000
Q13.8 Other congenital malformations of anterior segment of eye	0.001	0.999	0.000
Q13.5 Blue sclera	0.001	0.999	0.000
Q13.4 Other congenital corneal malformations	0.001	0.999	0.000
Q13.3 Congenital corneal opacity	0.001	0.999	0.000
Q13.2 Other congenital malformations of iris	0.001	0.999	0.000
Q13.1 Absence of iris	0.001	0.999	0.000
Q13.0 Coloboma of iris	0.001	0.999	0.000
Q14.9 Congenital malformation of posterior segment of eye, unspecified	0.001	0.999	0.000
Q14.8 Other congenital malformations of posterior segment of eye	0.001	0.999	0.000
Q14.3 Congenital malformation of choroid	0.001	0.999	0.000
Q14.2 Congenital malformation of optic disk	0.001	0.999	0.000
Q14.1 Congenital malformation of retina	0.001	0.999	0.000
Q14.0 Congenital malformation of vitreous humour	0.001	0.999	0.000
Q16.9 Congenital malformation of ear causing impairment of hearing, unspecified	0.001	0.999	0.000
Q16.5 Congenital malformation of inner ear	0.001	0.999	0.000
Q16.4 Other congenital malformations of middle ear	0.001	0.999	0.000
Q16.3 Congenital malformation of ear ossicles	0.001	0.999	0.000
Q16.2 Absence of eustachian tube	0.001	0.999	0.000
Q16.1 Congenital absence, atresia and stricture of auditory canal (external)	0.001	0.999	0.000
Q16.0 Congenital absence of (ear) auricle	0.001	0.999	0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.001	0.999	0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.001	0.999	0.000
S13.6 Sprain and strain of joints and ligaments of other and unspecified parts of neck	0.001	0.999	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.000	0.999	0.001
M79.16 Myalgia (Lower leg)	0.000	0.999	0.001
Q17.9 Congenital malformation of ear, unspecified	0.001	0.999	0.000
Q17.8 Other specified congenital malformations of ear	0.001	0.999	0.000
Q17.4 Misplaced ear	0.001	0.999	0.000
Q17.3 Other misshapen ear	0.001	0.999	0.000
Q17.2 Microtia	0.001	0.999	0.000
Q17.1 Macrotia	0.001	0.999	0.000
Q17.0 Accessory auricle	0.001	0.999	0.000
Z59.0 Homelessness	0.001	0.999	0.000
Z83.0 Family history of human immunodeficiency virus [HIV]	0.000	0.999	0.001
L53 Other erythematous conditions	0.000	0.999	0.001
M62.89 Other specified disorders of muscle (Site unspecified)	0.001	0.999	0.000
Q51.3 Bicornate uterus	0.001	0.999	0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.001	0.999	0.000
Z83.1 Family history of other infectious and parasitic diseases	0.000	0.999	0.001
M62.86 Other specified disorders of muscle (Lower leg)	0.001	0.999	0.000
M79.80 Other specified soft tissue disorders (Multiple sites)	0.000	0.999	0.001
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.000	0.999	0.001
S12.90 Fracture of neck, part unspecified (closed)	0.001	0.999	0.000
G96.0 Cerebrospinal fluid leak	0.000	0.999	0.001
H50.1 Divergent concomitant strabismus	0.000	0.999	0.001
I35.8 Other aortic valve disorders	0.001	0.999	0.000
S12.2 Fracture of other specified cervical vertebra	0.001	0.999	0.000
S12.11 Fracture of second cervical vertebra (open)	0.001	0.999	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.001	0.999	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.001	0.999	0.000
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.000	0.999	0.001
M87.98 Osteonecrosis, unspecified (Other)	0.000	0.999	0.001
M87.96 Osteonecrosis, unspecified (Lower leg)	0.000	0.999	0.001
M87.94 Osteonecrosis, unspecified (Hand)	0.000	0.999	0.001
M87.93 Osteonecrosis, unspecified (Forearm)	0.000	0.999	0.001
M87.92 Osteonecrosis, unspecified (Upper arm)	0.000	0.999	0.001
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.000	0.999	0.001
H53.9 Visual disturbance, unspecified	0.000	0.999	0.001
I86.1 Scrotal varices	0.001	0.999	0.000
Q17.5 Prominent ear	0.001	0.999	0.000
S12.9 Fracture of neck, part unspecified	0.001	0.999	0.000
H59.8 Other postprocedural disorders of eye and adnexa	0.001	0.999	0.000
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate	0.000	0.999	0.001
M96.5 Postradiation scoliosis	0.000	0.999	0.001
M96.4 Postsurgical lordosis	0.000	0.999	0.001
M96.3 Postlaminectomy kyphosis	0.000	0.999	0.001
M96.2 Postradiation kyphosis	0.000	0.999	0.001
M50 Cervical disk disorders	0.000	0.999	0.001
M62.88 Other specified disorders of muscle (Other)	0.001	0.999	0.000
C49.2 Connective and soft tissue of lower limb, including hip	0.001	0.999	0.000
E21.3 Hyperparathyroidism, unspecified	0.000	0.999	0.001
I35.9 Aortic valve disorder, unspecified	0.001	0.999	0.000
L53.3 Other chronic figurate erythema	0.000	0.999	0.001
L53.2 Erythema marginatum	0.000	0.999	0.001
L53.1 Erythema annulare centrifugum	0.000	0.999	0.001
L53.0 Toxic erythema	0.000	0.999	0.001
M96.9 Postprocedural musculoskeletal disorder, unspecified	0.000	0.999	0.001
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.001	0.999	0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.000	0.999	0.001
S12 Fracture of neck	0.001	0.999	0.000
S12.21 Fracture of other specified cervical vertebra (open)	0.001	0.999	0.000
I35.1 Aortic (valve) insufficiency	0.001	0.999	0.000
G44 Other headache syndromes	0.000	0.999	0.001
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.001	0.999	0.000
S12.91 Fracture of neck, part unspecified (open)	0.001	0.999	0.000
F43.0 Acute stress reaction	0.001	0.999	0.000
M50.3 Other cervical disk degeneration	0.000	0.999	0.001
R46.4 Slowness and poor responsiveness	0.001	0.999	0.000
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.000	0.999	0.001
M96.65 Fracture of pelvis following insertion of orthopedic implant, joint prosthesis, or bone plate (Fx pelvis following insrt ortho implnt/prosth/bone plt)	0.000	0.999	0.001
M96.63 Fracture of radius or ulna following insertion of orthopedic implant, joint prosthesis, or bone plate	0.000	0.999	0.001
C18.0 Caecum	0.001	0.999	0.000
L53.8 Other specified erythematous conditions	0.000	0.999	0.001
L81.9 Disorder of pigmentation, unspecified	0.001	0.999	0.000
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.001	0.999	0.000
S12.0 Fracture of first cervical vertebra	0.001	0.999	0.000
S13.1 Dislocation of cervical vertebra	0.001	0.999	0.000
Z97.8 Presence of other specified devices	0.000	0.999	0.001
M46.42 Discitis, unspecified (Cervical region)	0.001	0.999	0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.001	0.999	0.000
N81.4 Uterovaginal prolapse, unspecified	0.000	0.999	0.001
S12.8 Fracture of other parts of neck	0.001	0.999	0.000
Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.999	0.001
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.001	0.999	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.001	0.999	0.000
M62.54 Muscle wasting and atrophy, not elsewhere classified (Hand)	0.001	0.999	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.001	0.999	0.000
J98.9 Respiratory disorder, unspecified	0.000	0.999	0.001
L93.0 Discoid lupus erythematosus	0.000	0.999	0.001
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.001	0.999	0.000
S12.7 Multiple fractures of cervical spine	0.001	0.999	0.000
S13.5 Sprain and strain of thyroid region	0.001	0.999	0.000
S13.3 Multiple dislocations of neck	0.001	0.999	0.000
S13.2 Dislocation of other and unspecified parts of neck	0.001	0.999	0.000
S13.0 Traumatic rupture of cervical intervertebral disk	0.001	0.999	0.000
V89.2 Person injured in unspecified motor-vehicle accident, traffic	0.000	0.999	0.001
E73 Lactose intolerance	0.001	0.999	0.000
Q51 Congenital malformations of uterus and cervix	0.001	0.999	0.000
M62.59 Muscle wasting and atrophy, not elsewhere classified (Site unspecified)	0.001	0.999	0.000
S12.01 Fracture of first cervical vertebra (open)	0.001	0.999	0.000
S12.00 Fracture of first cervical vertebra (closed)	0.001	0.999	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.001	0.999	0.000
I86.2 Pelvic varices	0.001	0.999	0.000
M50.8 Other cervical disk disorders	0.000	0.999	0.001
S14.1 Other and unspecified injuries of cervical spinal cord	0.001	0.999	0.000
M46.26 Osteomyelitis of vertebra (Lumbar region)	0.001	0.999	0.000
M62.11 Other rupture of muscle (nontraumatic) (Shoulder region)	0.001	0.999	0.000
M62.58 Muscle wasting and atrophy, not elsewhere classified (Other)	0.001	0.999	0.000
M62.57 Muscle wasting and atrophy, not elsewhere classified (Ankle and foot)	0.001	0.999	0.000
M62.56 Muscle wasting and atrophy, not elsewhere classified (Lower leg)	0.001	0.999	0.000
M62.55 Muscle wasting and atrophy, not elsewhere classified (Pelvic region and thigh)	0.001	0.999	0.000
M62.53 Muscle wasting and atrophy, not elsewhere classified (Forearm)	0.001	0.999	0.000
M62.52 Muscle wasting and atrophy, not elsewhere classified (Upper arm)	0.001	0.999	0.000
M62.51 Muscle wasting and atrophy, not elsewhere classified (Shoulder region)	0.001	0.999	0.000
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)	0.001	0.999	0.000
S12.71 Multiple fractures of cervical spine (open)	0.001	0.999	0.000
S12.81 Fracture of other parts of neck (open)	0.001	0.999	0.000
S12.80 Fracture of other parts of neck (closed)	0.001	0.999	0.000
E73.8 Other lactose intolerance	0.001	0.999	0.000
E73.1 Secondary lactase deficiency	0.001	0.999	0.000
E73.0 Congenital lactase deficiency	0.001	0.999	0.000
G44.8 Other specified headache syndromes	0.000	0.999	0.001
M25.6 Stiffness of joint, not elsewhere classified	0.001	0.999	0.000
M62.1 Other rupture of muscle (nontraumatic)	0.001	0.999	0.000
O30.0 Twin pregnancy	0.000	0.999	0.001
O44.0 Placenta praevia specified as without haemorrhage	0.000	0.999	0.001
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.001	0.999	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.001	0.999	0.000
Q51.6 Embryonic cyst of cervix	0.001	0.999	0.000
Q51.5 Agenesis and aplasia of cervix	0.001	0.999	0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.001	0.999	0.000
Q51.0 Agenesis and aplasia of uterus	0.001	0.999	0.000
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.001	0.999	0.000
Q87.3 Congenital malformation syndromes involving early overgrowth	0.001	0.999	0.000
V09.0 Pedestrian injured in nontraffic accident involving other and unspecified motor vehicles	0.001	0.999	0.000
Z11.0 Special screening examination for intestinal infectious diseases	0.001	0.999	0.000
M62 Other disorders of muscle	0.001	0.999	0.000
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)	0.001	0.999	0.000
G72.0 Drug-induced myopathy	0.001	0.999	0.000
M50.9 Cervical disk disorder, unspecified	0.000	0.999	0.001
V04.1 Traffic accident	0.001	0.999	0.000
D68 Other coagulation defects	0.001	0.999	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.001	0.999	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.001	0.999	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.001	0.999	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.001	0.999	0.000
M46.40 Discitis, unspecified (Multiple sites in spine)	0.001	0.999	0.000
M62.19 Other rupture of muscle (nontraumatic) (Site unspecified)	0.001	0.999	0.000
M62.18 Other rupture of muscle (nontraumatic) (Other)	0.001	0.999	0.000
M62.17 Other rupture of muscle (nontraumatic) (Ankle and foot)	0.001	0.999	0.000
M62.16 Other rupture of muscle (nontraumatic) (Lower leg)	0.001	0.999	0.000
M62.15 Other rupture of muscle (nontraumatic) (Pelvic region and thigh)	0.001	0.999	0.000
M62.14 Other rupture of muscle (nontraumatic) (Hand)	0.001	0.999	0.000
M62.13 Other rupture of muscle (nontraumatic) (Forearm)	0.001	0.999	0.000
M62.12 Other rupture of muscle (nontraumatic) (Upper arm)	0.001	0.999	0.000
M62.10 Other rupture of muscle (nontraumatic) (Multiple sites)	0.001	0.999	0.000
S12.70 Multiple fractures of cervical spine (closed)	0.001	0.999	0.000
C49.1 Connective and soft tissue of upper limb, including shoulder	0.001	0.999	0.000
D68.4 Acquired coagulation factor deficiency	0.001	0.999	0.000
D68.1 Hereditary factor XI deficiency	0.001	0.999	0.000
G44.1 Vascular headache, not elsewhere classified	0.000	0.999	0.001
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.001	0.999	0.000
M62.9 Disorder of muscle, unspecified	0.001	0.999	0.000
M62.4 Contracture of muscle	0.001	0.999	0.000
M62.3 Immobility syndrome (paraplegic)	0.001	0.999	0.000
M62.2 Ischaemic infarction of muscle	0.001	0.999	0.000
M62.0 Diastasis of muscle	0.001	0.999	0.000
Q87.4 Marfan's syndrome	0.001	0.999	0.000
Z04.8 Examination and observation for other specified reasons	0.000	0.999	0.001
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.001	0.999	0.000
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.001	0.999	0.000
M62.09 Diastasis of muscle (Site unspecified)	0.001	0.999	0.000
M62.08 Diastasis of muscle (Other)	0.001	0.999	0.000
M62.07 Diastasis of muscle (Ankle and foot)	0.001	0.999	0.000
M62.06 Diastasis of muscle (Lower leg)	0.001	0.999	0.000
M62.05 Diastasis of muscle (Pelvic region and thigh)	0.001	0.999	0.000
M62.04 Diastasis of muscle (Hand)	0.001	0.999	0.000
M62.03 Diastasis of muscle (Forearm)	0.001	0.999	0.000
M62.02 Diastasis of muscle (Upper arm)	0.001	0.999	0.000
M62.01 Diastasis of muscle (Shoulder region)	0.001	0.999	0.000
M62.00 Diastasis of muscle (Multiple sites)	0.001	0.999	0.000
M62.29 Ischaemic infarction of muscle (Site unspecified)	0.001	0.999	0.000
M62.28 Ischaemic infarction of muscle (Other)	0.001	0.999	0.000
M62.27 Ischaemic infarction of muscle (Ankle and foot)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations